Lista de obras - John D. Lipscomb - Dominio Público Uruguay

6-phenylpyrrolocytosine as a fluorescent probe to examine nucleotide flipping catalyzed by a DNA repair protein

artículo científico publicado en 2020

A Long-Lived Fe(III)-(Hydroperoxo) Intermediate in the Active H200C Variant of Homoprotocatechuate 2,3-Dioxygenase: Characterization by Mössbauer, Electron Paramagnetic Resonance, and Density Functional Theory Methods.

artículo científico publicado en 2015

A Role of the Putidaredoxin COOH-terminus in P -450 cam (Cytochrome m ) Hydroxylations ⬇️

artículo científico publicado el 1 de octubre de 1974

A hyperactive cobalt-substituted extradiol-cleaving catechol dioxygenase

artículo científico publicado en 2011

A two-electron-shell game: intermediates of the extradiol-cleaving catechol dioxygenases

artículo científico publicado en 2014

Active-site structure of a β-hydroxylase in antibiotic biosynthesis

artículo científico publicado en 2011

Allosteric Control of O2 Reactivity in Rieske Oxygenases

artículo científico publicado en 2005

An Fe2IVO2 Diamond Core Structure for the Key Intermediate Q of Methane Monooxygenase

artículo científico publicado en 1997

An unusual peroxo intermediate of the arylamine oxygenase of the chloramphenicol biosynthetic pathway

artículo científico publicado en 2015

Aromatic ring cleavage by homoprotocatechuate 2,3-dioxygenase: role of His200 in the kinetics of interconversion of reaction cycle intermediates

artículo científico publicado en 2005

Benzoate 1,2-dioxygenase from Pseudomonas putida: single turnover kinetics and regulation of a two-component Rieske dioxygenase

artículo científico publicado en 2002

Biochemical and spectroscopic studies on (S)-2-hydroxypropylphosphonic acid epoxidase: a novel mononuclear non-heme iron enzyme

artículo científico publicado en 2003

CD and MCD studies of the effects of component B variant binding on the biferrous active site of methane monooxygenase.

scientific article published on 16 July 2008

CYTOCHROME P-450***amSUBSTRATE AND EFFECTOR INTERACTIONS

artículo científico publicado en 1973

Catalase (KatA) plays a role in protection against anaerobic nitric oxide in Pseudomonas aeruginosa

artículo científico publicado en 2014

Characterization of an O2 adduct of an active cobalt-substituted extradiol-cleaving catechol dioxygenase

artículo científico publicado en 2011

Cloning, overexpression, and mutagenesis of the gene for homoprotocatechuate 2,3-dioxygenase from Brevibacterium fuscum.

artículo científico publicado en 1997

CmlI N-Oxygenase Catalyzes the Final Three Steps in Chloramphenicol Biosynthesis without Dissociation of Intermediates

artículo científico publicado en 2017

Conversion of extradiol aromatic ring-cleaving homoprotocatechuate 2,3-dioxygenase into an intradiol cleaving enzyme

artículo científico publicado en 2003

Crystal Structure and Resonance Raman Studies of Protocatechuate 3,4- Dioxygenase Complexed with 3,4-Dihydroxyphenylacetate, ⬇️

artículo científico publicado el 23 de septiembre de 1997

Crystal structure of CmlI, the arylamine oxygenase from the chloramphenicol biosynthetic pathway

artículo científico publicado en 2016

Crystal structures of alkylperoxo and anhydride intermediates in an intradiol ring-cleaving dioxygenase.

artículo científico publicado en 2014

Crystal structures of substrate and substrate analog complexes of protocatechuate 3,4-dioxygenase: endogenous Fe3+ ligand displacement in response to substrate binding

artículo científico publicado en 1997

Cyanide and Nitric Oxide Binding to Reduced Protocatechuate 3,4-Dioxygenase: Insight into the Basis for Order-Dependent Ligand Binding by Intradiol Catecholic Dioxygenases ⬇️

artículo científico publicado el 18 de noviembre de 1997

Cyanobacterial aldehyde deformylase oxygenation of aldehydes yields n-1 aldehydes and alcohols in addition to alkanes

scientific article published on October 2013

Cytochrome P450 cam: SS- dimer and -SH derivative reactivities

artículo científico publicado en 1978

Desaturation reactions catalyzed by soluble methane monooxygenase

artículo científico publicado en 2001

Determination of the iron(IV) local spin states of the Q intermediate of soluble methane monooxygenase by Kβ X-ray emission spectroscopy

artículo científico publicado en 2022

Determination of the quaternary structure of protocatechuate 3,4-dioxygenase from Pseudomonas aeruginosa

artículo científico publicado en 1987

Determination of the substrate binding mode to the active site iron of (S)-2-hydroxypropylphosphonic acid epoxidase using 17O-enriched substrates and substrate analogues

artículo científico publicado en 2007

Diiron monooxygenases in natural product biosynthesis

artículo científico publicado en 2018

ENDOR studies of the ligation and structure of the non-heme iron site in ACC oxidase

artículo científico publicado en 2005

Effector proteins from P450(cam) and methane monooxygenase: lessons in tuning nature's powerful reagents

artículo científico publicado en 2003

Electron paramagnetic resonance detection of intermediates in the enzymatic cycle of an extradiol dioxygenase

artículo científico publicado en 2008

Enzyme Substrate Complex of the H200C Variant of Homoprotocatechuate 2,3-Dioxygenase: Mössbauer and Computational Studies

artículo científico publicado en 2016

Equilibrating (L)FeIII-OOAc and (L)FeV(O) Species in Hydrocarbon Oxidations by Bio-Inspired Nonheme Iron Catalysts Using H2O2 and AcOH.

artículo científico publicado en 2017

Finding intermediates in the O2 activation pathways of non-heme iron oxygenases.

artículo científico publicado en 2007

Gating Effects of Component B on Oxygen Activation by the Methane Monooxygenase Hydroxylase Component

artículo científico publicado en 1995

High-Energy-Resolution Fluorescence-Detected X-ray Absorption of the Q Intermediate of Soluble Methane Monooxygenase.

artículo científico publicado en 2017

High-Resolution EXAFS Provides Evidence for a Longer Fe•••Fe Distance in the Q Intermediate of Methane Monooxygenase

article

Hydrogen peroxide sensitivity of catechol-2,3-dioxygenase: a cautionary note on use of xylE reporter fusions under aerobic conditions

artículo científico publicado en 2000

Hydrogen peroxide-coupled cis-diol formation catalyzed by naphthalene 1,2-dioxygenase

artículo científico publicado en 2002

Intermediate P* from soluble methane monooxygenase contains a diferrous cluster

artículo científico publicado en 2013

Intermediate Q from soluble methane monooxygenase hydroxylates the mechanistic substrate probe norcarane: evidence for a stepwise reaction

artículo científico publicado en 2001

Intermediate in the O−O Bond Cleavage Reaction of an Extradiol Dioxygenase † , ‡

artículo científico publicado en 2008

Key amino acid residues in the regulation of soluble methane monooxygenase catalysis by component B.

artículo científico publicado en 2003

Kinetics and Activation Thermodynamics of Methane Monooxygenase CompoundQFormation and Reaction with Substrates†

article

Large Kinetic Isotope Effects in Methane Oxidation Catalyzed by Methane Monooxygenase: Evidence for C−H Bond Cleavage in a Reaction Cycle Intermediate†

article

Life in a sea of oxygen.

artículo científico publicado en 2014

Mechanism for Six-Electron Aryl-N-Oxygenation by the Non-Heme Diiron Enzyme CmlI.

artículo científico publicado en 2016

Mechanistic insights into C-H activation from radical clock chemistry: oxidation of substituted methylcyclopropanes catalyzed by soluble methane monooxygenase from Methylosinus trichosporium OB3b.

artículo científico publicado en 2000

Mechanistic studies of 1-aminocyclopropane-1-carboxylic acid oxidase: single turnover reaction

artículo científico publicado en 2004

Methane monooxygenase component B mutants alter the kinetics of steps throughout the catalytic cycle

artículo científico publicado en 2001

Methane monooxygenase hydroxylase and B component interactions.

artículo científico publicado en 2006

Modulation of substrate binding to naphthalene 1,2-dioxygenase by rieske cluster reduction/oxidation

artículo científico publicado en 2003

Mössbauer and EPR spectroscopy of protocatechuate 3,4-dioxygenase from Pseudomonas aeruginosa

artículo científico publicado en 1976

NO binding to Mn-substituted homoprotocatechuate 2,3-dioxygenase: relationship to O₂ reactivity

artículo científico publicado en 2013

NRVS Studies of the Peroxide Shunt Intermediate in a Rieske Dioxygenase and Its Relation to the Native FeII O2 Reaction.

artículo científico publicado en 2018

Near-IR MCD of the nonheme ferrous active site in naphthalene 1,2-dioxygenase: correlation to crystallography and structural insight into the mechanism of Rieske dioxygenases

artículo científico publicado en 2008

Nuclear Resonance Vibrational Spectroscopy Definition of O2 Intermediates in an Extradiol Dioxygenase: Correlation to Crystallography and Reactivity

scientific article published on 26 November 2018

Oxy intermediates of homoprotocatechuate 2,3-dioxygenase: facile electron transfer between substrates

artículo científico publicado en 2011

Oxygen activation catalyzed by methane monooxygenase hydroxylase component: proton delivery during the O-O bond cleavage steps

artículo científico publicado en 1999

P-450cam hydroxylase: substrate-effector and electron-transport reactions

artículo científico publicado en 1971

Preliminary Crystallographic Analysis of Methane Mono-oxygenase Hydroxylase from Methylosinus trichosporium OB3b

artículo científico publicado en 1994

Preliminary Crystallographic Study of Protocatechuate 3,4-Dioxygenase from Brevibacterium fuscum

artículo científico publicado en 1994

Protocatechuate 3,4-dioxygenase. Inhibitor studies and mechanistic implications

artículo científico publicado en 1977

Purification of a high specific activity methane monooxygenase hydroxylase component from a type II methanotroph

artículo científico publicado en 1988

Radical intermediates in monooxygenase reactions of rieske dioxygenases

artículo científico publicado en 2007

Radiolytic Reduction of Methane Monooxygenase Dinuclear Iron Cluster at 77 K

scientific article published in Journal of Biological Chemistry

Rate-Determining Attack on Substrate Precedes Rieske Cluster Oxidation during Cis-Dihydroxylation by Benzoate Dioxygenase

artículo científico publicado en 2015

Regulation of methane monooxygenase catalysis based on size exclusion and quantum tunneling

artículo científico publicado en 2006

Residues inMethylosinus trichosporiumOB3b Methane Monooxygenase Component B Involved in Molecular Interactions with Reduced- and Oxidized-Hydroxylase Component: A Role for the N-Terminus†

article

Role of the C-terminal region of the B component of Methylosinus trichosporium OB3b methane monooxygenase in the regulation of oxygen activation

artículo científico publicado en 2006

Roles of the Methane Monooxygenase Reductase Component in the Regulation of Catalysis†

article

Roles of the equatorial tyrosyl iron ligand of protocatechuate 3,4-dioxygenase in catalysis

artículo científico publicado en 2005

Salicylate 5-Hydroxylase: Intermediates in Aromatic Hydroxylation by a Rieske Monooxygenase

scientific article published on 15 May 2019

Single-turnover kinetics of homoprotocatechuate 2,3-dioxygenase

artículo científico publicado en 2004

Site-directed mutagenesis and spectroscopic studies of the iron-binding site of (S)-2-hydroxypropylphosphonic acid epoxidase

artículo científico publicado en 2005

Spectroscopic and electronic structure studies of protocatechuate 3,4-dioxygenase: nature of tyrosinate-Fe(III) bonds and their contribution to reactivity

artículo científico publicado en 2002

Spectroscopic and electronic structure study of the enzyme-substrate complex of intradiol dioxygenases: substrate activation by a high-spin ferric non-heme iron site

artículo científico publicado en 2007

Spectroscopic studies of 1-aminocyclopropane-1-carboxylic acid oxidase: molecular mechanism and CO(2) activation in the biosynthesis of ethylene

artículo científico publicado en 2002

Spectroscopic studies of the anaerobic enzyme-substrate complex of catechol 1,2-dioxygenase

artículo científico publicado en 2005

Spectroscopic studies of the effect of ligand donor strength on the Fe-NO bond intradiol dioxygenases.

artículo científico publicado en 2003

Structural Basis for Substrate and Oxygen Activation in Homoprotocatechuate 2,3-Dioxygenase: Roles of Conserved Active Site Histidine 200

artículo científico publicado en 2015

Structural Basis for the Role of Tyrosine 257 of Homoprotocatechuate 2,3-Dioxygenase in Substrate and Oxygen Activation

artículo científico publicado en 2012

Structural and Molecular Characterization of Iron-sensing Hemerythrin-like Domain within F-box and Leucine-rich Repeat Protein 5 (FBXL5)

artículo científico publicado en 2012

Structure of a Dinuclear Iron Cluster-Containing β-Hydroxylase Active in Antibiotic Biosynthesis

artículo científico publicado en 2013

Structure of the key species in the enzymatic oxidation of methane to methanol

artículo científico publicado en 2015

Structures of Competitive Inhibitor Complexes of Protocatechuate 3,4-Dioxygenase: Multiple Exogenous Ligand Binding Orientations within the Active Site, ⬇️

artículo científico publicado el 19 de agosto de 1997

Substrate binding to NO-ferro-naphthalene 1,2-dioxygenase studied by high-resolution Q-band pulsed 2H-ENDOR spectroscopy

artículo científico publicado en 2003

Substrate radical intermediates in soluble methane monooxygenase

artículo científico publicado en 2005

Substrate-mediated oxygen activation by homoprotocatechuate 2,3-dioxygenase: intermediates formed by a tyrosine 257 variant.

artículo científico publicado en 2012

Superoxide anion production by the autoxidation of cytochrome P450cam

article

Swapping metals in Fe- and Mn-dependent dioxygenases: Evidence for oxygen activation without a change in metal redox state

artículo científico publicado en 2008

The axial tyrosinate Fe3+ ligand in protocatechuate 3,4-dioxygenase influences substrate binding and product release: evidence for new reaction cycle intermediates

artículo científico publicado en 1998

The magnetic susceptibility of reduced cytochrome P-450-cam

artículo científico publicado en 1975

Trapping and spectroscopic characterization of an FeIII-superoxo intermediate from a nonheme mononuclear iron-containing enzyme ⬇️

artículo científico publicado el 13 de septiembre de 2010

Two-pronged survival strategy for the major cystic fibrosis pathogen, Pseudomonas aeruginosa, lacking the capacity to degrade nitric oxide during anaerobic respiration.

artículo científico publicado en 2007

Unmasking of Deuterium Kinetic Isotope Effects on the Methane Monooxygenase Compound Q Reaction by Site-Directed Mutagenesis of Component B

artículo científico publicado en 2001

Unprecedented (μ-1,1-Peroxo)diferric Structure for the Ambiphilic Orange Peroxo Intermediate of the Nonheme N-Oxygenase CmlI.

artículo científico publicado en 2017

VTVH-MCD and DFT studies of thiolate bonding to [FeNO]7/[FeO2]8 complexes of isopenicillin N synthase: substrate determination of oxidase versus oxygenase activity in nonheme Fe enzymes

artículo científico publicado en 2007

Versatility of biological non-heme Fe(II) centers in oxygen activation reactions.

artículo científico publicado en 2008

X-ray absorption spectroscopic studies of the Fe(II) active site of catechol 2,3-dioxygenase. Implications for the extradiol cleavage mechanism

article

Lista de obras de John D. Lipscomb

6-phenylpyrrolocytosine as a fluorescent probe to examine nucleotide flipping catalyzed by a DNA repair protein

A Long-Lived Fe(III)-(Hydroperoxo) Intermediate in the Active H200C Variant of Homoprotocatechuate 2,3-Dioxygenase: Characterization by Mössbauer, Electron Paramagnetic Resonance, and Density Functional Theory Methods.

A Role of the Putidaredoxin COOH-terminus in P -450 cam (Cytochrome m ) Hydroxylations ⬇️

A hyperactive cobalt-substituted extradiol-cleaving catechol dioxygenase

A two-electron-shell game: intermediates of the extradiol-cleaving catechol dioxygenases

Active-site structure of a β-hydroxylase in antibiotic biosynthesis

Allosteric Control of O2 Reactivity in Rieske Oxygenases

An Fe2IVO2 Diamond Core Structure for the Key Intermediate Q of Methane Monooxygenase

An unusual peroxo intermediate of the arylamine oxygenase of the chloramphenicol biosynthetic pathway

Aromatic ring cleavage by homoprotocatechuate 2,3-dioxygenase: role of His200 in the kinetics of interconversion of reaction cycle intermediates

Benzoate 1,2-dioxygenase from Pseudomonas putida: single turnover kinetics and regulation of a two-component Rieske dioxygenase

Biochemical and spectroscopic studies on (S)-2-hydroxypropylphosphonic acid epoxidase: a novel mononuclear non-heme iron enzyme

CD and MCD studies of the effects of component B variant binding on the biferrous active site of methane monooxygenase.

CYTOCHROME P-450***amSUBSTRATE AND EFFECTOR INTERACTIONS

Catalase (KatA) plays a role in protection against anaerobic nitric oxide in Pseudomonas aeruginosa

Characterization of an O2 adduct of an active cobalt-substituted extradiol-cleaving catechol dioxygenase

Cloning, overexpression, and mutagenesis of the gene for homoprotocatechuate 2,3-dioxygenase from Brevibacterium fuscum.

CmlI N-Oxygenase Catalyzes the Final Three Steps in Chloramphenicol Biosynthesis without Dissociation of Intermediates

Conversion of extradiol aromatic ring-cleaving homoprotocatechuate 2,3-dioxygenase into an intradiol cleaving enzyme

Crystal Structure and Resonance Raman Studies of Protocatechuate 3,4- Dioxygenase Complexed with 3,4-Dihydroxyphenylacetate, ⬇️

Crystal structure of CmlI, the arylamine oxygenase from the chloramphenicol biosynthetic pathway

Crystal structures of alkylperoxo and anhydride intermediates in an intradiol ring-cleaving dioxygenase.

Crystal structures of substrate and substrate analog complexes of protocatechuate 3,4-dioxygenase: endogenous Fe3+ ligand displacement in response to substrate binding

Cyanide and Nitric Oxide Binding to Reduced Protocatechuate 3,4-Dioxygenase: Insight into the Basis for Order-Dependent Ligand Binding by Intradiol Catecholic Dioxygenases ⬇️

Cyanobacterial aldehyde deformylase oxygenation of aldehydes yields n-1 aldehydes and alcohols in addition to alkanes

Cytochrome P450 cam: SS- dimer and -SH derivative reactivities

Desaturation reactions catalyzed by soluble methane monooxygenase

Determination of the iron(IV) local spin states of the Q intermediate of soluble methane monooxygenase by Kβ X-ray emission spectroscopy

Determination of the quaternary structure of protocatechuate 3,4-dioxygenase from Pseudomonas aeruginosa

Determination of the substrate binding mode to the active site iron of (S)-2-hydroxypropylphosphonic acid epoxidase using 17O-enriched substrates and substrate analogues

Diiron monooxygenases in natural product biosynthesis

ENDOR studies of the ligation and structure of the non-heme iron site in ACC oxidase

Effector proteins from P450(cam) and methane monooxygenase: lessons in tuning nature's powerful reagents

Electron paramagnetic resonance detection of intermediates in the enzymatic cycle of an extradiol dioxygenase

Enzyme Substrate Complex of the H200C Variant of Homoprotocatechuate 2,3-Dioxygenase: Mössbauer and Computational Studies

Equilibrating (L)FeIII-OOAc and (L)FeV(O) Species in Hydrocarbon Oxidations by Bio-Inspired Nonheme Iron Catalysts Using H2O2 and AcOH.

Finding intermediates in the O2 activation pathways of non-heme iron oxygenases.

Gating Effects of Component B on Oxygen Activation by the Methane Monooxygenase Hydroxylase Component

High-Energy-Resolution Fluorescence-Detected X-ray Absorption of the Q Intermediate of Soluble Methane Monooxygenase.

High-Resolution EXAFS Provides Evidence for a Longer Fe•••Fe Distance in the Q Intermediate of Methane Monooxygenase

Hydrogen peroxide sensitivity of catechol-2,3-dioxygenase: a cautionary note on use of xylE reporter fusions under aerobic conditions

Hydrogen peroxide-coupled cis-diol formation catalyzed by naphthalene 1,2-dioxygenase

Intermediate P* from soluble methane monooxygenase contains a diferrous cluster

Intermediate Q from soluble methane monooxygenase hydroxylates the mechanistic substrate probe norcarane: evidence for a stepwise reaction

Intermediate in the O−O Bond Cleavage Reaction of an Extradiol Dioxygenase † , ‡

Key amino acid residues in the regulation of soluble methane monooxygenase catalysis by component B.

Kinetics and Activation Thermodynamics of Methane Monooxygenase CompoundQFormation and Reaction with Substrates†

Large Kinetic Isotope Effects in Methane Oxidation Catalyzed by Methane Monooxygenase: Evidence for C−H Bond Cleavage in a Reaction Cycle Intermediate†

Life in a sea of oxygen.

Mechanism for Six-Electron Aryl-N-Oxygenation by the Non-Heme Diiron Enzyme CmlI.

Mechanistic insights into C-H activation from radical clock chemistry: oxidation of substituted methylcyclopropanes catalyzed by soluble methane monooxygenase from Methylosinus trichosporium OB3b.

Mechanistic studies of 1-aminocyclopropane-1-carboxylic acid oxidase: single turnover reaction

Methane monooxygenase component B mutants alter the kinetics of steps throughout the catalytic cycle

Methane monooxygenase hydroxylase and B component interactions.

Modulation of substrate binding to naphthalene 1,2-dioxygenase by rieske cluster reduction/oxidation

Mössbauer and EPR spectroscopy of protocatechuate 3,4-dioxygenase from Pseudomonas aeruginosa

NO binding to Mn-substituted homoprotocatechuate 2,3-dioxygenase: relationship to O₂ reactivity

NRVS Studies of the Peroxide Shunt Intermediate in a Rieske Dioxygenase and Its Relation to the Native FeII O2 Reaction.

Near-IR MCD of the nonheme ferrous active site in naphthalene 1,2-dioxygenase: correlation to crystallography and structural insight into the mechanism of Rieske dioxygenases

Nuclear Resonance Vibrational Spectroscopy Definition of O2 Intermediates in an Extradiol Dioxygenase: Correlation to Crystallography and Reactivity

Oxy intermediates of homoprotocatechuate 2,3-dioxygenase: facile electron transfer between substrates

Oxygen activation catalyzed by methane monooxygenase hydroxylase component: proton delivery during the O-O bond cleavage steps

P-450cam hydroxylase: substrate-effector and electron-transport reactions

Preliminary Crystallographic Analysis of Methane Mono-oxygenase Hydroxylase from Methylosinus trichosporium OB3b

Preliminary Crystallographic Study of Protocatechuate 3,4-Dioxygenase from Brevibacterium fuscum

Protocatechuate 3,4-dioxygenase. Inhibitor studies and mechanistic implications

Purification of a high specific activity methane monooxygenase hydroxylase component from a type II methanotroph

Radical intermediates in monooxygenase reactions of rieske dioxygenases

Radiolytic Reduction of Methane Monooxygenase Dinuclear Iron Cluster at 77 K

Rate-Determining Attack on Substrate Precedes Rieske Cluster Oxidation during Cis-Dihydroxylation by Benzoate Dioxygenase

Regulation of methane monooxygenase catalysis based on size exclusion and quantum tunneling

Residues inMethylosinus trichosporiumOB3b Methane Monooxygenase Component B Involved in Molecular Interactions with Reduced- and Oxidized-Hydroxylase Component: A Role for the N-Terminus†

Role of the C-terminal region of the B component of Methylosinus trichosporium OB3b methane monooxygenase in the regulation of oxygen activation

Roles of the Methane Monooxygenase Reductase Component in the Regulation of Catalysis†

Roles of the equatorial tyrosyl iron ligand of protocatechuate 3,4-dioxygenase in catalysis

Salicylate 5-Hydroxylase: Intermediates in Aromatic Hydroxylation by a Rieske Monooxygenase

Single-turnover kinetics of homoprotocatechuate 2,3-dioxygenase

Site-directed mutagenesis and spectroscopic studies of the iron-binding site of (S)-2-hydroxypropylphosphonic acid epoxidase

Spectroscopic and electronic structure studies of protocatechuate 3,4-dioxygenase: nature of tyrosinate-Fe(III) bonds and their contribution to reactivity