Lista de obras - Alexander W. Tarr - Dominio Público Uruguay

A Diverse Panel of Hepatitis C Virus Glycoproteins for Use in Vaccine Research Reveals Extremes of Monoclonal Antibody Neutralization Resistance.

artículo científico publicado en 2015

An alpaca nanobody inhibits hepatitis C virus entry and cell-to-cell transmission

artículo científico publicado en 2013

Analysis of serine codon conservation reveals diverse phenotypic constraints on hepatitis C virus glycoprotein evolution

artículo científico publicado en 2014

Analysis of the binding of hepatitis C virus genotype 1a and 1b E2 glycoproteins to peripheral blood mononuclear cell subsets

artículo científico publicado en 2005

Association of antibodies to hepatitis C virus glycoproteins 1 and 2 (anti-E1E2) with HCV disease.

artículo científico publicado en 2008

B-cell receptors expressed by lymphomas of hepatitis C virus (HCV)-infected patients rarely react with the viral proteins

artículo científico publicado en 2014

Broadly neutralizing antibodies protect against hepatitis C virus quasispecies challenge

artículo científico publicado en 2007

Characterization of host-range and cell entry properties of the major genotypes and subtypes of hepatitis C virus

artículo científico publicado en 2005

Characterization of the hepatitis C virus E2 epitope defined by the broadly neutralizing monoclonal antibody AP33.

artículo científico publicado en 2006

Cloning and Analysis of Authentic Patient-Derived HCV E1/E2 Glycoproteins

artículo científico publicado en 2019

Cloning, expression, and functional analysis of patient-derived hepatitis C virus glycoproteins.

artículo científico publicado en 2007

Colicin import into E. coli cells: a model system for insights into the import mechanisms of bacteriocins

artículo científico publicado en 2014

Cross-genotype AR3-specific neutralizing antibodies confer long-term protection in injecting drug users after HCV clearance

scientific article published on 21 February 2019

Cross-genotype characterization of genetic diversity and molecular adaptation in hepatitis C virus envelope glycoprotein genes

artículo científico publicado en 2007

Determination of the human antibody response to the epitope defined by the hepatitis C virus-neutralizing monoclonal antibody AP33.

artículo científico publicado en 2007

Dramatic potentiation of the antiviral activity of HIV antibodies by cholesterol conjugation

artículo científico publicado en 2014

Elevated serum activity of MBL and ficolin-2 as biomarkers for progression to hepatocellular carcinoma in chronic HCV infection

scientific article published on 12 February 2019

Enhanced nanoparticle uptake into virus infected cells: Could nanoparticles be useful in antiviral therapy?

scientific article published on 13 June 2018

Enterovirus D68 epidemic, UK, 2018, was caused by subclades B3 and D1, predominantly in children and adults, respectively, with both subclades exhibiting extensive genetic diversity

artículo científico publicado en 2022

Entry inhibition of HSV-1 and -2 protects mice from viral lethal challenge

artículo científico publicado en 2017

Evolutionary dynamics of hepatitis C virus envelope genes during chronic infection.

artículo científico publicado en 2005

Expression of human ficolin-2 in hepatocytes confers resistance to infection by diverse hepatotropic viruses

scientific article published on 12 February 2019

Flexible and rapid construction of viral chimeras applied to hepatitis C virus.

artículo científico publicado en 2016

Functional and immunogenic characterization of diverse HCV glycoprotein E2 variants

artículo científico publicado en 2018

Genetic Diversity Underlying the Envelope Glycoproteins of Hepatitis C Virus: Structural and Functional Consequences and the Implications for Vaccine Design

artículo científico publicado en 2015

Hepatitis C Virus Vaccine: Challenges and Prospects

artículo científico publicado en 2020

Hepatitis C patient-derived glycoproteins exhibit marked differences in susceptibility to serum neutralizing antibodies: genetic subtype defines antigenic but not neutralization serotype.

artículo científico publicado en 2011

Hepatitis C virus envelope glycoprotein fitness defines virus population composition following transmission to a new host

artículo científico publicado en 2012

Hepatitis C virus quasispecies and pseudotype analysis from acute infection to chronicity in HIV-1 co-infected individuals

artículo científico publicado en 2016

High resolution sequencing of hepatitis C virus reveals limited intra-hepatic compartmentalization in end-stage liver disease. ⬇️

artículo científico publicado en 2016

Human Bocavirus infection and respiratory tract disease identified in a UK patient cohort

scientific article published on 21 May 2020

Human combinatorial libraries yield rare antibodies that broadly neutralize hepatitis C virus

artículo científico publicado en 2007

Human lectins and their roles in viral infections.

artículo científico publicado en 2015

Human parainfluenza 2 & 4: Clinical and genetic epidemiology in the UK, 2013–2017, reveals distinct disease features and co‐circulating genomic subtypes

artículo científico publicado en 2022

Identification of Conserved Residues in the E2 Envelope Glycoprotein of the Hepatitis C Virus That Are Critical for CD81 Binding

artículo científico publicado en 2006

Identification of New Functional Regions in Hepatitis C Virus Envelope Glycoprotein E2

artículo científico publicado en 2011

Identification of a Broadly Cross-Reacting and Neutralizing Human Monoclonal Antibody Directed against the Hepatitis C Virus E2 Protein

artículo científico publicado en 2008

Immunization with a synthetic consensus hepatitis C virus E2 glycoprotein ectodomain elicits virus-neutralizing antibodies

artículo científico publicado en 2018

InFusion Cloning for the Generation of Biologically Relevant HCV Chimeric Molecular Clones

artículo científico publicado en 2019

Monoclonal Antibody AP33 Defines a Broadly Neutralizing Epitope on the Hepatitis C Virus E2 Envelope Glycoprotein

artículo científico publicado en 2005

Naturally occurring antibodies that recognize linear epitopes in the amino terminus of the hepatitis C virus E2 protein confer noninterfering, additive neutralization

artículo científico publicado en 2012

Non-ionic detergents facilitate non-specific binding of M13 bacteriophage to polystyrene surfaces.

artículo científico publicado en 2015

Novel functional hepatitis C virus glycoprotein isolates identified using an optimized viral pseudotype entry assay.

artículo científico publicado en 2016

Perceptions and Experiences of the University of Nottingham Pilot SARS-CoV-2 Asymptomatic Testing Service: A Mixed-Methods Study

scientific article published on 29 December 2020

Rationally derived inhibitors of hepatitis C virus (HCV) p7 channel activity reveal prospect for bimodal antiviral therapy

artículo científico publicado en 2020

Recombinant human L-ficolin directly neutralizes hepatitis C virus entry.

artículo científico publicado en 2014

Specific interaction of hepatitis C virus glycoproteins with mannan binding lectin inhibits virus entry.

artículo científico publicado en 2010

Structural and antigenic definition of hepatitis C virus E2 glycoprotein epitopes targeted by monoclonal antibodies

artículo científico publicado en 2013

Structural flexibility of a conserved antigenic region in hepatitis C virus glycoprotein E2 recognized by broadly neutralizing antibodies.

artículo científico publicado en 2014

Tagged polymerase chain reaction subtractive hybridization for the enrichment of phage display random peptide libraries.

artículo científico publicado en 2005

Technical considerations for the generation of novel pseudotyped viruses

The HCV Envelope Glycoprotein Down-Modulates NF-κB Signalling and Associates With Stimulation of the Host Endoplasmic Reticulum Stress Pathway

artículo científico publicado en 2022

The P body protein LSm1 contributes to stimulation of hepatitis C virus translation, but not replication, by microRNA-122

artículo científico publicado en 2013

The past, present and future of neutralizing antibodies for hepatitis C virus

artículo científico publicado en 2014

The role of humoral innate immunity in hepatitis C virus infection.

artículo científico

The role of neutralizing antibodies in hepatitis C virus infection.

artículo científico publicado en 2011

Type I interferon rapidly restricts infectious hepatitis C virus particle genesis.

artículo científico publicado en 2014

Lista de obras de Alexander W. Tarr

A Diverse Panel of Hepatitis C Virus Glycoproteins for Use in Vaccine Research Reveals Extremes of Monoclonal Antibody Neutralization Resistance.

An alpaca nanobody inhibits hepatitis C virus entry and cell-to-cell transmission

Analysis of serine codon conservation reveals diverse phenotypic constraints on hepatitis C virus glycoprotein evolution

Analysis of the binding of hepatitis C virus genotype 1a and 1b E2 glycoproteins to peripheral blood mononuclear cell subsets

Association of antibodies to hepatitis C virus glycoproteins 1 and 2 (anti-E1E2) with HCV disease.

B-cell receptors expressed by lymphomas of hepatitis C virus (HCV)-infected patients rarely react with the viral proteins

Broadly neutralizing antibodies protect against hepatitis C virus quasispecies challenge

Characterization of host-range and cell entry properties of the major genotypes and subtypes of hepatitis C virus

Characterization of the hepatitis C virus E2 epitope defined by the broadly neutralizing monoclonal antibody AP33.

Cloning and Analysis of Authentic Patient-Derived HCV E1/E2 Glycoproteins

Cloning, expression, and functional analysis of patient-derived hepatitis C virus glycoproteins.

Colicin import into E. coli cells: a model system for insights into the import mechanisms of bacteriocins

Cross-genotype AR3-specific neutralizing antibodies confer long-term protection in injecting drug users after HCV clearance

Cross-genotype characterization of genetic diversity and molecular adaptation in hepatitis C virus envelope glycoprotein genes

Determination of the human antibody response to the epitope defined by the hepatitis C virus-neutralizing monoclonal antibody AP33.

Dramatic potentiation of the antiviral activity of HIV antibodies by cholesterol conjugation

Elevated serum activity of MBL and ficolin-2 as biomarkers for progression to hepatocellular carcinoma in chronic HCV infection

Enhanced nanoparticle uptake into virus infected cells: Could nanoparticles be useful in antiviral therapy?

Enterovirus D68 epidemic, UK, 2018, was caused by subclades B3 and D1, predominantly in children and adults, respectively, with both subclades exhibiting extensive genetic diversity

Entry inhibition of HSV-1 and -2 protects mice from viral lethal challenge

Evolutionary dynamics of hepatitis C virus envelope genes during chronic infection.

Expression of human ficolin-2 in hepatocytes confers resistance to infection by diverse hepatotropic viruses

Flexible and rapid construction of viral chimeras applied to hepatitis C virus.

Functional and immunogenic characterization of diverse HCV glycoprotein E2 variants

Genetic Diversity Underlying the Envelope Glycoproteins of Hepatitis C Virus: Structural and Functional Consequences and the Implications for Vaccine Design

Hepatitis C Virus Vaccine: Challenges and Prospects

Hepatitis C patient-derived glycoproteins exhibit marked differences in susceptibility to serum neutralizing antibodies: genetic subtype defines antigenic but not neutralization serotype.

Hepatitis C virus envelope glycoprotein fitness defines virus population composition following transmission to a new host

Hepatitis C virus quasispecies and pseudotype analysis from acute infection to chronicity in HIV-1 co-infected individuals

High resolution sequencing of hepatitis C virus reveals limited intra-hepatic compartmentalization in end-stage liver disease. ⬇️

Human Bocavirus infection and respiratory tract disease identified in a UK patient cohort

Human combinatorial libraries yield rare antibodies that broadly neutralize hepatitis C virus

Human lectins and their roles in viral infections.

Human parainfluenza 2 & 4: Clinical and genetic epidemiology in the UK, 2013–2017, reveals distinct disease features and co‐circulating genomic subtypes

Identification of Conserved Residues in the E2 Envelope Glycoprotein of the Hepatitis C Virus That Are Critical for CD81 Binding

Identification of New Functional Regions in Hepatitis C Virus Envelope Glycoprotein E2

Identification of a Broadly Cross-Reacting and Neutralizing Human Monoclonal Antibody Directed against the Hepatitis C Virus E2 Protein

Immunization with a synthetic consensus hepatitis C virus E2 glycoprotein ectodomain elicits virus-neutralizing antibodies

InFusion Cloning for the Generation of Biologically Relevant HCV Chimeric Molecular Clones

Monoclonal Antibody AP33 Defines a Broadly Neutralizing Epitope on the Hepatitis C Virus E2 Envelope Glycoprotein

Naturally occurring antibodies that recognize linear epitopes in the amino terminus of the hepatitis C virus E2 protein confer noninterfering, additive neutralization

Non-ionic detergents facilitate non-specific binding of M13 bacteriophage to polystyrene surfaces.

Novel functional hepatitis C virus glycoprotein isolates identified using an optimized viral pseudotype entry assay.

Perceptions and Experiences of the University of Nottingham Pilot SARS-CoV-2 Asymptomatic Testing Service: A Mixed-Methods Study

Rationally derived inhibitors of hepatitis C virus (HCV) p7 channel activity reveal prospect for bimodal antiviral therapy

Recombinant human L-ficolin directly neutralizes hepatitis C virus entry.

Specific interaction of hepatitis C virus glycoproteins with mannan binding lectin inhibits virus entry.

Structural and antigenic definition of hepatitis C virus E2 glycoprotein epitopes targeted by monoclonal antibodies

Structural flexibility of a conserved antigenic region in hepatitis C virus glycoprotein E2 recognized by broadly neutralizing antibodies.

Tagged polymerase chain reaction subtractive hybridization for the enrichment of phage display random peptide libraries.

Technical considerations for the generation of novel pseudotyped viruses

The HCV Envelope Glycoprotein Down-Modulates NF-κB Signalling and Associates With Stimulation of the Host Endoplasmic Reticulum Stress Pathway

The P body protein LSm1 contributes to stimulation of hepatitis C virus translation, but not replication, by microRNA-122

The past, present and future of neutralizing antibodies for hepatitis C virus

The role of humoral innate immunity in hepatitis C virus infection.

The role of neutralizing antibodies in hepatitis C virus infection.

Type I interferon rapidly restricts infectious hepatitis C virus particle genesis.