Lista de obras - Mark H. Kaplan - Dominio Público Uruguay

A conserved enhancer regulates Il9 expression in multiple lineages

artículo científico publicado en 2018

A gut reaction to IL-9.

artículo científico publicado en 2014

Altered STAT4 Isoform Expression in Patients with Inflammatory Bowel Disease.

artículo científico publicado en 2015

Altered cytokine production by dendritic cells from infants with atopic dermatitis ⬇️

artículo científico publicado el 29 de septiembre de 2010

An Inhibitory Role for the Transcription Factor Stat3 in Controlling IL-4 and Bcl6 Expression in Follicular Helper T Cells

artículo científico publicado en 2015

Anti-STAT6 CTL activity in Stat6 (-/-) mice: A cautionary tale

artículo científico publicado en 2013

BATF-Interacting Proteins Dictate Specificity in Th Subset Activity

scientific article published on 26 August 2019

CD4+ T-cell-mediated anti-tumor immunity can be uncoupled from autoimmunity via the STAT4/STAT6 signaling axis

artículo científico publicado en 2009

Calcitriol Regulates the Differentiation of IL-9-Secreting Th9 Cells by Modulating the Transcription Factor PU.1.

scientific article published on 13 January 2020

Covalent Heterobivalent Inhibitor Design for Inhibition of IgE-Dependent Penicillin Allergy in a Murine Model

scientific article published on 17 May 2019

Differential requirement of signal transducer and activator of transcription-4 (Stat4) and Stat6 in a thyrotropin receptor-289-adenovirus-induced model of Graves' hyperthyroidism.

artículo científico publicado en 2005

Distinct requirements for Stat4 and Stat6 in hematopoietic progenitor cell responses to growth factors and chemokines

scientific article published on 01 August 2003

Diverse inflammatory cytokines induce selectin ligand expression on murine CD4 T cells via p38α MAPK.

artículo científico publicado en 2015

Elevated IL-6 expression in CD4 T cells via PKCtheta and NF-kappaB induces Th2 cytokine production

artículo científico publicado en 2009

Endonuclease and redox activities of human apurinic/apyrimidinic endonuclease 1 have distinctive and essential functions in IgA class switch recombination

artículo científico publicado en 2019

Etv5 Regulates IL-10 Production in Th Cells

artículo científico publicado en 2017

Expression Efficiency of Multiple Il9 Reporter Alleles Is Determined by Cell Lineage

scientific article published on 21 May 2020

Expression of a constitutively active Stat6 in vivo alters lymphocyte homeostasis with distinct effects in T and B cells

artículo científico publicado en 2003

Gcn5 is required for PU.1-dependent IL-9 induction in Th9 cells.

artículo científico publicado en 2012

IL-9 by INFERence

artículo científico publicado en 2013

IRF4 Modulates CD8 T Cell Sensitivity to IL-2 Family Cytokines

artículo científico publicado en 2017

Impaired IL-12 responses and enhanced development of Th2 cells in Stat4-deficient mice

artículo científico publicado en 1996

Impaired development of human Th1 cells in patients with deficient expression of STAT4.

artículo científico publicado en 2009

Increased skin barrier disruption by sodium lauryl sulfate in mice expressing a constitutively active STAT6 in T cells.

artículo científico publicado en 2011

Mast Cells Regulate Epidermal Barrier Function and the Development of Allergic Skin Inflammation.

artículo científico

Mechanism for Initiation of Food Allergy: Dependence on skin barrier mutations and environmental allergen co-stimulation.

artículo científico publicado en 2018

Mouse pulmonary interstitial macrophages mediate the pro-tumorigenic effects of IL-9

artículo científico publicado en 2022

Neonatal tolerance in the absence of Stat4- and Stat6- dependent Th cell differentiation

artículo científico publicado en 2002

Opening the Black Box of Immunosuppression

scientific article published on 01 December 2018

Opposing Roles of STAT4 and Dnmt3a in Th1 Gene Regulation ⬇️

artículo científico publicado el 14 de junio de 2013

PARP14 limits severity of allergic skin disease

artículo científico publicado en 2017

PD-1hi CD8+ resident memory T cells balance immunity and fibrotic sequelae

scientific article published on 01 June 2019

PPAR-γ in Macrophages Limits Pulmonary Inflammation and Promotes Host Recovery following Respiratory Viral Infection

scientific article published on 17 April 2019

PU.1 Expression in T Follicular Helper Cells Limits CD40L-Dependent Germinal Center B Cell Development

artículo científico publicado en 2015

PU.1 expression delineates heterogeneity in primary Th2 cells.

artículo científico publicado en 2005

Paracrine IL-2 Is Required for Optimal Type 2 Effector Cytokine Production.

artículo científico publicado en 2017

Platelet-Activating Factor-Induced Reduction in Contact Hypersensitivity Responses Is Mediated by Mast Cells via Cyclooxygenase-2-Dependent Mechanisms

artículo científico publicado en 2018

Predisposition to the development of IL-9–secreting T cells in atopic infants ⬇️

artículo científico publicado el 28 de julio de 2011

ResTORing barrier function in the skin

artículo científico publicado en 2019

Resolution of inflammation by interleukin-9-producing type 2 innate lymphoid cells

artículo científico publicado en 2017

Roles of T Follicular Helper Cells and T Follicular Regulatory Cells in Autoantibody Production in IL-2-Deficient Mice

artículo científico publicado en 2019

STAT3 Activation Impairs the Stability of Th9 Cells

artículo científico publicado en 2017

STAT3 Impairs STAT5 Activation in the Development of IL-9-Secreting T Cells

artículo científico publicado en 2016

STAT4 Regulates the CD8+ Regulatory T Cell/T Follicular Helper Cell Axis and Promotes Atherogenesis in Insulin-Resistant Ldlr-/- Mice.

artículo científico publicado en 2017

STAT4 deficiency reduces the development of atherosclerosis in mice

artículo científico publicado en 2015

STAT4 is critical for immunity but not for antileishmanial activity of antimonials in experimental visceral leishmaniasis.

artículo científico publicado en 2013

STAT4 is required for IL-23 responsiveness in Th17 memory cells and NKT cells

artículo científico publicado en 2014

STAT4 requires the N-terminal domain for efficient phosphorylation

artículo científico publicado en 2003

STAT4: a critical regulator of inflammation in vivo

artículo científico publicado en 2005

STAT5 promotes accessibility and is required for BATF-mediated plasticity at the Il9 locus

artículo científico publicado en 2020

STAT6 and Furin Are Successive Triggers for the Production of TGF-β by T Cells

artículo científico publicado en 2018

STAT6-Dependent Regulation of Th9 Development ⬇️

artículo científico publicado el 16 de diciembre de 2011

STAT6-mediated keratitis and blepharitis: a novel murine model of ocular atopic dermatitis

artículo científico publicado en 2014

Scratching the surface: towards understanding the pathogenesis of atopic dermatitis.

artículo científico publicado en 2008

Signal transducer and activator of transcription (Stat)-6-dependent, but not Stat4-dependent, immunity is required for the development of autoimmunity in Graves' hyperthyroidism

artículo científico publicado en 2004

Signal transducer and activator of transcription 4 limits the development of adaptive regulatory T cells

article

Specifically differentiated T cell subset promotes tumor immunity over fatal immunity.

artículo científico publicado en 2017

Stat4 limits DNA methyltransferase recruitment and DNA methylation of the IL-18Ralpha gene during Th1 differentiation

artículo científico publicado en 2007

Stat6 is required for mediating responses to IL-4 and for development of Th2 cells.

artículo científico publicado en 1996

Stat6-deficient mice develop airway hyperresponsiveness and peribronchial fibrosis during chronic fungal asthma.

artículo científico publicado en 2002

TH9 cells are required for tissue mast cell accumulation during allergic inflammation

artículo científico publicado en 2015

Th9 cell development requires a BATF-regulated transcriptional network

artículo científico publicado en 2013

Th9 cells: differentiation and disease.

artículo científico publicado en 2013

The ETS Family Transcription Factors Etv5 and PU.1 Function in Parallel To Promote Th9 Cell Development

artículo científico publicado en 2016

The Il9 CNS-25 Regulatory Element Controls Mast Cell and Basophil IL-9 Production

artículo científico publicado en 2019

The TNF-family ligand TL1A and its receptor DR3 promote T cell-mediated allergic immunopathology by enhancing differentiation and pathogenicity of IL-9-producing T cells.

artículo científico publicado en 2015

The signal transducer and activator of transcription 6 gene (STAT6) increases the propensity of patients with atopic dermatitis toward disseminated viral skin infections.

artículo científico publicado en 2011

The symphony of the ninth: the development and function of Th9 cells

artículo científico

The transcription factor Etv5 controls TH17 cell development and allergic airway inflammation.

artículo científico publicado en 2014

The transcription factor PU.1 is required for the development of IL-9-producing T cells and allergic inflammation.

artículo científico publicado en 2010

The transcription factor PU.1 regulates γδ T cell homeostasis

artículo científico publicado en 2011

The transcription factor STAT3 is required for T helper 2 cell development

artículo científico publicado en 2011

The transcription factor Twist1 limits T helper 17 and T follicular helper cell development by repressing the gene encoding the interleukin-6 receptor α chain.

artículo científico publicado en 2013

The transcriptional repressor Bcl6 controls the stability of regulatory T cells by intrinsic and extrinsic pathways

artículo científico publicado en 2015

Tissue-resident CD4<sup>+</sup> T helper cells assist the development of protective respiratory B and CD8<sup>+</sup> T cell memory responses

artículo científico publicado en 2021

Topical application of a vitamin D analogue exacerbates atopic dermatitis and induces the atopic dermatitis-like phenotype in Stat6VT mice.

artículo científico publicado en 2013

Transcriptional regulation by STAT6.

artículo científico publicado en 2011

Twist1 regulates Ifng expression in Th1 cells by interfering with Runx3 function.

artículo científico publicado en 2012

Yoking OX40 to regulation of IL-9.

artículo científico publicado en 2012

γδ T cell IFNγ production is directly subverted by Yersinia pseudotuberculosis outer protein YopJ in mice and humans

artículo científico publicado en 2021

Lista de obras de Mark H. Kaplan

A conserved enhancer regulates Il9 expression in multiple lineages

A gut reaction to IL-9.

Altered STAT4 Isoform Expression in Patients with Inflammatory Bowel Disease.

Altered cytokine production by dendritic cells from infants with atopic dermatitis ⬇️

An Inhibitory Role for the Transcription Factor Stat3 in Controlling IL-4 and Bcl6 Expression in Follicular Helper T Cells

Anti-STAT6 CTL activity in Stat6 (-/-) mice: A cautionary tale

BATF-Interacting Proteins Dictate Specificity in Th Subset Activity

CD4+ T-cell-mediated anti-tumor immunity can be uncoupled from autoimmunity via the STAT4/STAT6 signaling axis

Calcitriol Regulates the Differentiation of IL-9-Secreting Th9 Cells by Modulating the Transcription Factor PU.1.

Covalent Heterobivalent Inhibitor Design for Inhibition of IgE-Dependent Penicillin Allergy in a Murine Model

Differential requirement of signal transducer and activator of transcription-4 (Stat4) and Stat6 in a thyrotropin receptor-289-adenovirus-induced model of Graves' hyperthyroidism.

Distinct requirements for Stat4 and Stat6 in hematopoietic progenitor cell responses to growth factors and chemokines

Diverse inflammatory cytokines induce selectin ligand expression on murine CD4 T cells via p38α MAPK.

Elevated IL-6 expression in CD4 T cells via PKCtheta and NF-kappaB induces Th2 cytokine production

Endonuclease and redox activities of human apurinic/apyrimidinic endonuclease 1 have distinctive and essential functions in IgA class switch recombination

Etv5 Regulates IL-10 Production in Th Cells

Expression Efficiency of Multiple Il9 Reporter Alleles Is Determined by Cell Lineage

Expression of a constitutively active Stat6 in vivo alters lymphocyte homeostasis with distinct effects in T and B cells

Gcn5 is required for PU.1-dependent IL-9 induction in Th9 cells.

IL-9 by INFERence

IRF4 Modulates CD8 T Cell Sensitivity to IL-2 Family Cytokines

Impaired IL-12 responses and enhanced development of Th2 cells in Stat4-deficient mice

Impaired development of human Th1 cells in patients with deficient expression of STAT4.

Increased skin barrier disruption by sodium lauryl sulfate in mice expressing a constitutively active STAT6 in T cells.

Mast Cells Regulate Epidermal Barrier Function and the Development of Allergic Skin Inflammation.

Mechanism for Initiation of Food Allergy: Dependence on skin barrier mutations and environmental allergen co-stimulation.

Mouse pulmonary interstitial macrophages mediate the pro-tumorigenic effects of IL-9

Neonatal tolerance in the absence of Stat4- and Stat6- dependent Th cell differentiation

Opening the Black Box of Immunosuppression

Opposing Roles of STAT4 and Dnmt3a in Th1 Gene Regulation ⬇️

PARP14 limits severity of allergic skin disease

PD-1hi CD8+ resident memory T cells balance immunity and fibrotic sequelae

PPAR-γ in Macrophages Limits Pulmonary Inflammation and Promotes Host Recovery following Respiratory Viral Infection

PU.1 Expression in T Follicular Helper Cells Limits CD40L-Dependent Germinal Center B Cell Development

PU.1 expression delineates heterogeneity in primary Th2 cells.

Paracrine IL-2 Is Required for Optimal Type 2 Effector Cytokine Production.

Platelet-Activating Factor-Induced Reduction in Contact Hypersensitivity Responses Is Mediated by Mast Cells via Cyclooxygenase-2-Dependent Mechanisms

Predisposition to the development of IL-9–secreting T cells in atopic infants ⬇️

ResTORing barrier function in the skin

Resolution of inflammation by interleukin-9-producing type 2 innate lymphoid cells

Roles of T Follicular Helper Cells and T Follicular Regulatory Cells in Autoantibody Production in IL-2-Deficient Mice

STAT3 Activation Impairs the Stability of Th9 Cells

STAT3 Impairs STAT5 Activation in the Development of IL-9-Secreting T Cells

STAT4 Regulates the CD8+ Regulatory T Cell/T Follicular Helper Cell Axis and Promotes Atherogenesis in Insulin-Resistant Ldlr-/- Mice.

STAT4 deficiency reduces the development of atherosclerosis in mice

STAT4 is critical for immunity but not for antileishmanial activity of antimonials in experimental visceral leishmaniasis.

STAT4 is required for IL-23 responsiveness in Th17 memory cells and NKT cells

STAT4 requires the N-terminal domain for efficient phosphorylation

STAT4: a critical regulator of inflammation in vivo

STAT5 promotes accessibility and is required for BATF-mediated plasticity at the Il9 locus

STAT6 and Furin Are Successive Triggers for the Production of TGF-β by T Cells

STAT6-Dependent Regulation of Th9 Development ⬇️

STAT6-mediated keratitis and blepharitis: a novel murine model of ocular atopic dermatitis

Scratching the surface: towards understanding the pathogenesis of atopic dermatitis.

Signal transducer and activator of transcription (Stat)-6-dependent, but not Stat4-dependent, immunity is required for the development of autoimmunity in Graves' hyperthyroidism

Signal transducer and activator of transcription 4 limits the development of adaptive regulatory T cells

Specifically differentiated T cell subset promotes tumor immunity over fatal immunity.

Stat4 limits DNA methyltransferase recruitment and DNA methylation of the IL-18Ralpha gene during Th1 differentiation

Stat6 is required for mediating responses to IL-4 and for development of Th2 cells.

Stat6-deficient mice develop airway hyperresponsiveness and peribronchial fibrosis during chronic fungal asthma.

TH9 cells are required for tissue mast cell accumulation during allergic inflammation

Th9 cell development requires a BATF-regulated transcriptional network

Th9 cells: differentiation and disease.

The ETS Family Transcription Factors Etv5 and PU.1 Function in Parallel To Promote Th9 Cell Development

The Il9 CNS-25 Regulatory Element Controls Mast Cell and Basophil IL-9 Production

The TNF-family ligand TL1A and its receptor DR3 promote T cell-mediated allergic immunopathology by enhancing differentiation and pathogenicity of IL-9-producing T cells.

The signal transducer and activator of transcription 6 gene (STAT6) increases the propensity of patients with atopic dermatitis toward disseminated viral skin infections.

The symphony of the ninth: the development and function of Th9 cells

The transcription factor Etv5 controls TH17 cell development and allergic airway inflammation.

The transcription factor PU.1 is required for the development of IL-9-producing T cells and allergic inflammation.

The transcription factor PU.1 regulates γδ T cell homeostasis

The transcription factor STAT3 is required for T helper 2 cell development

The transcription factor Twist1 limits T helper 17 and T follicular helper cell development by repressing the gene encoding the interleukin-6 receptor α chain.

The transcriptional repressor Bcl6 controls the stability of regulatory T cells by intrinsic and extrinsic pathways

Tissue-resident CD4<sup>+</sup> T helper cells assist the development of protective respiratory B and CD8<sup>+</sup> T cell memory responses

Topical application of a vitamin D analogue exacerbates atopic dermatitis and induces the atopic dermatitis-like phenotype in Stat6VT mice.

Transcriptional regulation by STAT6.

Twist1 regulates Ifng expression in Th1 cells by interfering with Runx3 function.

Yoking OX40 to regulation of IL-9.