Lista de obras - Stefan Feske - Dominio Público Uruguay

A 10-aa-long sequence in SLP-76 upstream of the Gads binding site is essential for T cell development and function.

artículo científico publicado en 2005

A minimal regulatory domain in the C terminus of STIM1 binds to and activates ORAI1 CRAC channels

artículo científico publicado en 2009

A molecular dissection of lymphocyte unresponsiveness induced by sustained calcium signalling.

artículo científico publicado en 2005

A novel mutation in ORAI1 presenting with combined immunodeficiency and residual T-cell function

artículo científico publicado en 2015

Agonist-selected T cell development requires strong T cell receptor signaling and store-operated calcium entry.

artículo científico publicado en 2013

Antiviral and regulatory T cell immunity in a patient with stromal interaction molecule 1 deficiency

artículo científico publicado en 2011

B cell receptor-mediated calcium signaling is impaired in B lymphocytes of type Ia patients with common variable immunodeficiency

artículo científico publicado en 2010

Biochemical and functional characterization of Orai proteins

artículo científico publicado en 2007

CD4⁺ and CD8⁺ T cell-dependent antiviral immunity requires STIM1 and STIM2.

artículo científico publicado en 2014

CRAC channelopathies

artículo científico publicado en 2010

CRAC channels and disease - From human CRAC channelopathies and animal models to novel drugs

artículo científico publicado en 2019

Ca(2+) influx in T cells: how many ca(2+) channels?

artículo científico publicado en 2013

Ca2+ Signaling but Not Store-Operated Ca2+ Entry Is Required for the Function of Macrophages and Dendritic Cells

artículo científico publicado en 2015

Ca2+ transport and signalling in enamel cells

artículo científico publicado en 2016

Ca2+/calcineurin signalling in cells of the immune system ⬇️

artículo científico publicado el 28 de noviembre de 2003

Calcineurin imposes T cell unresponsiveness through targeted proteolysis of signaling proteins

artículo científico publicado en 2004

Calcium Signaling Controls Pathogenic Th17 Cell-Mediated Inflammation by Regulating Mitochondrial Function

scientific article published on 14 February 2019

Calcium signalling in lymphocyte activation and disease

artículo científico publicado en 2007

Calpain 2 controls turnover of LFA-1 adhesions on migrating T lymphocytes

artículo científico publicado en 2010

Cavβ1 regulates T cell expansion and apoptosis independently of voltage-gated Ca<sup>2+</sup> channel function

artículo científico publicado en 2022

Conformational dynamics of STIM1 activation

artículo científico publicado en 2013

Defective nuclear translocation of nuclear factor of activated T cells and extracellular signal-regulated kinase underlies deficient IL-2 gene expression in Wiskott-Aldrich syndrome

artículo científico publicado en 2005

Dental enamel cells express functional SOCE channels.

artículo científico publicado en 2015

Differential regulation of Ca2+ influx by ORAI channels mediates enamel mineralization

artículo científico publicado en 2019

Diseases caused by mutations in ORAI1 and STIM1

artículo científico publicado en 2015

Dual functions for the endoplasmic reticulum calcium sensors STIM1 and STIM2 in T cell activation and tolerance

artículo científico publicado en 2008

Emerging roles of store-operated Ca²⁺ entry through STIM and ORAI proteins in immunity, hemostasis and cancer

artículo científico publicado en 2013

Essential role of Orai1 store-operated calcium channels in lactation

artículo científico publicado en 2015

Eye on ion channels in immune cells

artículo científico publicado en 2019

Functional Interrogation of Primary Human T Cells via CRISPR Genetic Editing

scholarly article by Xin Chen et al published 1 September 2018 in Journal of Immunology

Hair loss and defective T- and B-cell function in mice lacking ORAI1

artículo científico publicado en 2008

Hemophagocytic lymphohistiocytosis as presenting manifestation of profound combined immunodeficiency due to an ORAI1 mutation

artículo científico publicado en 2017

Immunodeficiency due to mutations in ORAI1 and STIM1.

artículo científico publicado en 2010

Impaired NFAT regulation and its role in a severe combined immunodeficiency

artículo científico publicado en 2000

InsP₃receptors and Orai channels in pancreatic acinar cells: co-localization and its consequences

scientific journal article

Interference with Ca(2+) release activated Ca(2+) (CRAC) channel function delays T-cell arrest in vivo

artículo científico publicado en 2013

Ion channelopathies of the immune system.

artículo científico publicado en 2018

Ion channels in innate and adaptive immunity

artículo científico publicado en 2015

Missense mutation in immunodeficient patients shows the multifunctional roles of coiled-coil domain 3 (CC3) in STIM1 activation

artículo científico publicado en 2015

NFAT control of immune function: New Frontiers for an Abiding Trooper.

artículo científico publicado en 2018

ORAI1 and STIM1 deficiency in human and mice: roles of store-operated Ca2+ entry in the immune system and beyond.

artículo científico publicado en 2009

ORAI1 deficiency and lack of store-operated Ca2+ entry cause immunodeficiency, myopathy, and ectodermal dysplasia

artículo científico publicado en 2009

ORAI1 mutations abolishing store-operated Ca2+ entry cause anhidrotic ectodermal dysplasia with immunodeficiency

artículo científico publicado en 2017

ORAI1, STIM1/2, and RYR1 shape subsecond Ca2+ microdomains upon T cell activation

artículo científico publicado en 2018

Perforin triggers a plasma membrane-repair response that facilitates CTL induction of apoptosis

artículo científico publicado en 2005

Phosphoenolpyruvate Is a Metabolic Checkpoint of Anti-tumor T Cell Responses.

artículo científico publicado en 2015

Polarized but differential localization and recruitment of STIM1, Orai1 and TRPC channels in secretory cells.

artículo científico publicado en 2010

Preserved effector functions of human ORAI1- and STIM1-deficient neutrophils

artículo científico publicado en 2015

Protein kinase C-induced phosphorylation of Orai1 regulates the intracellular Ca2+ level via the store-operated Ca2+ channel.

artículo científico publicado en 2010

Reduced synaptic STIM2 expression and impaired store-operated calcium entry cause destabilization of mature spines in mutant presenilin mice

artículo científico publicado en 2014

Regulation of lymphocyte function by ORAI and STIM proteins in infection and autoimmunity.

artículo científico publicado en 2012

Relative contributions of stromal interaction molecule 1 and CalDAG-GEFI to calcium-dependent platelet activation and thrombosis.

artículo científico publicado en 2011

Ribosome-free terminals of rough ER allow formation of STIM1 puncta and segregation of STIM1 from IP(3) receptors.

artículo científico publicado en 2009

STIM1 and STIM2 Mediate Cancer-Induced Inflammation in T Cell Acute Lymphoblastic Leukemia

artículo científico publicado en 2018

STIM1 and STIM2-mediated Ca(2+) influx regulates antitumour immunity by CD8(+) T cells

artículo científico publicado en 2013

STIM1 controls T cell-mediated immune regulation and inflammation in chronic infection

artículo científico publicado en 2015

STIM1 mutation associated with a syndrome of immunodeficiency and autoimmunity

artículo científico publicado en 2009

STIM1-mediated calcium influx controls antifungal immunity and the metabolic function of non-pathogenic Th17 cells

artículo científico publicado en 2020

STIM2 enhances receptor-stimulated Ca²⁺ signaling by promoting recruitment of STIM1 to the endoplasmic reticulum-plasma membrane junctions.

artículo científico publicado en 2015

STIM2 targets Orai1/STIM1 to the AKAP79 signaling complex and confers coupling of Ca2+ entry with NFAT1 activation

scientific article published on 29 June 2020

Seeing is believing: Visualizing immune cells and calcium signals at different stages of neuroinflammation

artículo científico publicado en 2020

Severe combined immunodeficiency due to defective binding of the nuclear factor of activated T cells in T lymphocytes of two male siblings

artículo científico publicado en 1996

Signalling to transcription: store-operated Ca2+ entry and NFAT activation in lymphocytes.

artículo científico publicado en 2007

Store-Operated Ca(2+) Entry in Follicular T Cells Controls Humoral Immune Responses and Autoimmunity

artículo científico publicado en 2016

Store-Operated Ca2+ Entry Controls Clonal Expansion of T Cells through Metabolic Reprogramming.

artículo científico publicado en 2017

Store-operated CRAC channels regulate gene expression and proliferation in neural progenitor cells

artículo científico publicado en 2014

Store-operated Ca2+ Entry Modulates the Expression of Enamel Genes.

artículo científico publicado en 2015

Store-operated Ca2+ entry (SOCE) regulates melanoma proliferation and cell migration

artículo científico publicado en 2014

Store-operated Ca2+ entry in primary murine lung fibroblasts is independent of classical transient receptor potential (TRPC) channels and contributes to cell migration

artículo científico publicado en 2020

Store-operated Ca2+ entry regulates Ca2+-activated chloride channels and eccrine sweat gland function

scientific article published on 10 October 2016

Store-operated Ca2+ entry through ORAI1 is critical for T cell-mediated autoimmunity and allograft rejection

artículo científico publicado en 2010

T-cell-specific deletion of STIM1 and STIM2 protects mice from EAE by impairing the effector functions of Th1 and Th17 cells

artículo científico publicado en 2010

The duration of nuclear residence of NFAT determines the pattern of cytokine expression in human SCID T cells

scientific article published on 01 July 2000

The volume-regulated anion channel LRRC8C suppresses T cell function by regulating cyclic dinucleotide transport and STING-p53 signaling

artículo científico publicado en 2022

Tissue resident and follicular Treg cell differentiation is regulated by CRAC channels

artículo científico publicado en 2019

Two types of functionally distinct Ca2+ stores in hippocampal neurons

scientific article published on 19 July 2019

Whole-exome sequencing-based discovery of STIM1 deficiency in a child with fatal classic Kaposi sarcoma

artículo científico publicado en 2010

Lista de obras de Stefan Feske

A 10-aa-long sequence in SLP-76 upstream of the Gads binding site is essential for T cell development and function.

A minimal regulatory domain in the C terminus of STIM1 binds to and activates ORAI1 CRAC channels

A molecular dissection of lymphocyte unresponsiveness induced by sustained calcium signalling.

A novel mutation in ORAI1 presenting with combined immunodeficiency and residual T-cell function

Agonist-selected T cell development requires strong T cell receptor signaling and store-operated calcium entry.

Antiviral and regulatory T cell immunity in a patient with stromal interaction molecule 1 deficiency

B cell receptor-mediated calcium signaling is impaired in B lymphocytes of type Ia patients with common variable immunodeficiency

Biochemical and functional characterization of Orai proteins

CD4⁺ and CD8⁺ T cell-dependent antiviral immunity requires STIM1 and STIM2.

CRAC channelopathies

CRAC channels and disease - From human CRAC channelopathies and animal models to novel drugs

Ca(2+) influx in T cells: how many ca(2+) channels?

Ca2+ Signaling but Not Store-Operated Ca2+ Entry Is Required for the Function of Macrophages and Dendritic Cells

Ca2+ transport and signalling in enamel cells

Ca2+/calcineurin signalling in cells of the immune system ⬇️

Calcineurin imposes T cell unresponsiveness through targeted proteolysis of signaling proteins

Calcium Signaling Controls Pathogenic Th17 Cell-Mediated Inflammation by Regulating Mitochondrial Function

Calcium signalling in lymphocyte activation and disease

Calpain 2 controls turnover of LFA-1 adhesions on migrating T lymphocytes

Cavβ1 regulates T cell expansion and apoptosis independently of voltage-gated Ca<sup>2+</sup> channel function

Conformational dynamics of STIM1 activation

Defective nuclear translocation of nuclear factor of activated T cells and extracellular signal-regulated kinase underlies deficient IL-2 gene expression in Wiskott-Aldrich syndrome

Dental enamel cells express functional SOCE channels.

Differential regulation of Ca2+ influx by ORAI channels mediates enamel mineralization

Diseases caused by mutations in ORAI1 and STIM1

Dual functions for the endoplasmic reticulum calcium sensors STIM1 and STIM2 in T cell activation and tolerance

Emerging roles of store-operated Ca²⁺ entry through STIM and ORAI proteins in immunity, hemostasis and cancer

Essential role of Orai1 store-operated calcium channels in lactation

Eye on ion channels in immune cells

Functional Interrogation of Primary Human T Cells via CRISPR Genetic Editing

Hair loss and defective T- and B-cell function in mice lacking ORAI1

Hemophagocytic lymphohistiocytosis as presenting manifestation of profound combined immunodeficiency due to an ORAI1 mutation

Immunodeficiency due to mutations in ORAI1 and STIM1.

Impaired NFAT regulation and its role in a severe combined immunodeficiency

InsP₃receptors and Orai channels in pancreatic acinar cells: co-localization and its consequences

Interference with Ca(2+) release activated Ca(2+) (CRAC) channel function delays T-cell arrest in vivo

Ion channelopathies of the immune system.

Ion channels in innate and adaptive immunity

Missense mutation in immunodeficient patients shows the multifunctional roles of coiled-coil domain 3 (CC3) in STIM1 activation

NFAT control of immune function: New Frontiers for an Abiding Trooper.

ORAI1 and STIM1 deficiency in human and mice: roles of store-operated Ca2+ entry in the immune system and beyond.

ORAI1 deficiency and lack of store-operated Ca2+ entry cause immunodeficiency, myopathy, and ectodermal dysplasia

ORAI1 mutations abolishing store-operated Ca2+ entry cause anhidrotic ectodermal dysplasia with immunodeficiency

ORAI1, STIM1/2, and RYR1 shape subsecond Ca2+ microdomains upon T cell activation

Perforin triggers a plasma membrane-repair response that facilitates CTL induction of apoptosis

Phosphoenolpyruvate Is a Metabolic Checkpoint of Anti-tumor T Cell Responses.

Polarized but differential localization and recruitment of STIM1, Orai1 and TRPC channels in secretory cells.

Preserved effector functions of human ORAI1- and STIM1-deficient neutrophils

Protein kinase C-induced phosphorylation of Orai1 regulates the intracellular Ca2+ level via the store-operated Ca2+ channel.

Reduced synaptic STIM2 expression and impaired store-operated calcium entry cause destabilization of mature spines in mutant presenilin mice

Regulation of lymphocyte function by ORAI and STIM proteins in infection and autoimmunity.

Relative contributions of stromal interaction molecule 1 and CalDAG-GEFI to calcium-dependent platelet activation and thrombosis.

Ribosome-free terminals of rough ER allow formation of STIM1 puncta and segregation of STIM1 from IP(3) receptors.

STIM1 and STIM2 Mediate Cancer-Induced Inflammation in T Cell Acute Lymphoblastic Leukemia

STIM1 and STIM2-mediated Ca(2+) influx regulates antitumour immunity by CD8(+) T cells

STIM1 controls T cell-mediated immune regulation and inflammation in chronic infection

STIM1 mutation associated with a syndrome of immunodeficiency and autoimmunity

STIM1-mediated calcium influx controls antifungal immunity and the metabolic function of non-pathogenic Th17 cells

STIM2 enhances receptor-stimulated Ca²⁺ signaling by promoting recruitment of STIM1 to the endoplasmic reticulum-plasma membrane junctions.

STIM2 targets Orai1/STIM1 to the AKAP79 signaling complex and confers coupling of Ca2+ entry with NFAT1 activation

Seeing is believing: Visualizing immune cells and calcium signals at different stages of neuroinflammation

Severe combined immunodeficiency due to defective binding of the nuclear factor of activated T cells in T lymphocytes of two male siblings

Signalling to transcription: store-operated Ca2+ entry and NFAT activation in lymphocytes.

Store-Operated Ca(2+) Entry in Follicular T Cells Controls Humoral Immune Responses and Autoimmunity

Store-Operated Ca2+ Entry Controls Clonal Expansion of T Cells through Metabolic Reprogramming.

Store-operated CRAC channels regulate gene expression and proliferation in neural progenitor cells

Store-operated Ca2+ Entry Modulates the Expression of Enamel Genes.

Store-operated Ca2+ entry (SOCE) regulates melanoma proliferation and cell migration

Store-operated Ca2+ entry in primary murine lung fibroblasts is independent of classical transient receptor potential (TRPC) channels and contributes to cell migration

Store-operated Ca2+ entry regulates Ca2+-activated chloride channels and eccrine sweat gland function

Store-operated Ca2+ entry through ORAI1 is critical for T cell-mediated autoimmunity and allograft rejection

T-cell-specific deletion of STIM1 and STIM2 protects mice from EAE by impairing the effector functions of Th1 and Th17 cells

The duration of nuclear residence of NFAT determines the pattern of cytokine expression in human SCID T cells

The volume-regulated anion channel LRRC8C suppresses T cell function by regulating cyclic dinucleotide transport and STING-p53 signaling

Tissue resident and follicular Treg cell differentiation is regulated by CRAC channels

Two types of functionally distinct Ca2+ stores in hippocampal neurons

Whole-exome sequencing-based discovery of STIM1 deficiency in a child with fatal classic Kaposi sarcoma