Lista de obras - Jerry E. Chipuk - Dominio Público Uruguay

Activation of Nrf2 Is Required for Normal and ChREBPα-Augmented Glucose-Stimulated β-Cell Proliferation

artículo científico publicado en 2018

Activation of the Mitochondrial Fragmentation Protein DRP1 Correlates with BRAF(V600E) Melanoma

artículo científico publicado en 2015

Aging of Antiviral CD8+ Memory T Cells Fosters Increased Survival, Metabolic Adaptations, and Lymphoid Tissue Homing

scientific article published on 14 December 2018

Anti-apoptotic BCL-2 proteins govern cellular outcome following B-RAF(V600E) inhibition and can be targeted to reduce resistance.

artículo científico publicado en 2014

Apoptosis: Stabbed in the BAX.

artículo científico publicado en 2008

B cell lymphoma-2 (BCL-2) homology domain 3 (BH3) mimetics demonstrate differential activities dependent upon the functional repertoire of pro- and anti-apoptotic BCL-2 family proteins

artículo científico publicado en 2014

BAK activation is necessary and sufficient to drive ceramide synthase-dependent ceramide accumulation following inhibition of BCL2-like proteins

artículo científico publicado en 2013

BAK/BAX activation and cytochrome c release assays using isolated mitochondria

artículo científico publicado en 2013

BCL-2 proteins: melanoma lives on the edge

artículo científico publicado en 2015

BH3 domains of BH3-only proteins differentially regulate Bax-mediated mitochondrial membrane permeabilization both directly and indirectly

artículo científico publicado en 2005

BH3 domains other than Bim and Bid can directly activate Bax/Bak

artículo científico publicado en 2011

Bcl-xL blocks transforming growth factor-beta 1-induced apoptosis by inhibiting cytochrome c release and not by directly antagonizing Apaf-1-dependent caspase activation in prostate epithelial cells

artículo científico publicado en 2001

Born to be alive: a role for the BCL-2 family in melanoma tumor cell survival, apoptosis, and treatment

artículo científico publicado en 2011

Cell death through the ages: The ICDS 25th Anniversary Meeting

artículo científico publicado en 2020

Chemical inhibition of the mitochondrial division dynamin reveals its role in Bax/Bak-dependent mitochondrial outer membrane permeabilization

artículo científico publicado en 2008

Connected to death: the (unexpurgated) mitochondrial pathway of apoptosis

artículo científico publicado en 2005

Death upon a kiss: mitochondrial outer membrane composition and organelle communication govern sensitivity to BAK/BAX-dependent apoptosis

artículo científico publicado en 2013

Direct activation of Bax by p53 mediates mitochondrial membrane permeabilization and apoptosis

artículo científico publicado en 2004

Disruption of mitochondrial electron transport chain function potentiates the pro-apoptotic effects of MAPK inhibition

artículo científico publicado en 2017

Dissecting p53-dependent apoptosis.

artículo científico publicado en 2006

Do inducers of apoptosis trigger caspase-independent cell death?

artículo científico publicado en 2005

Dual suppression of inner and outer mitochondrial membrane functions augments apoptotic responses to oncogenic MAPK inhibition

artículo científico publicado en 2018

Essential versus accessory aspects of cell death: recommendations of the NCCD 2015.

artículo científico publicado en 2014

Examining BCL-2 family function with large unilamellar vesicles

artículo científico publicado en 2012

FBXW7 regulates a mitochondrial transcription program by modulating MITF.

artículo científico publicado en 2018

From zero to sixty: cell death signaling in the city that never sleeps

artículo científico publicado en 2015

GM-CSF controls nonlymphoid tissue dendritic cell homeostasis but is dispensable for the differentiation of inflammatory dendritic cells

artículo científico publicado en 2012

Genetically defining the mechanism of Puma- and Bim-induced apoptosis

artículo científico publicado en 2011

Getting away with murder: how does the BCL-2 family of proteins kill with immunity?

artículo científico publicado en 2013

How do BCL-2 proteins induce mitochondrial outer membrane permeabilization?

artículo científico publicado en 2008

How do I kill thee? Let me count the ways: p53 regulates PARP-1 dependent necrosis

artículo científico

Identification and characterization of a novel rat ov-serpin family member, trespin

scientific journal article

Immune biomarkers are more accurate in prediction of survival in ulcerated than in non-ulcerated primary melanomas

artículo científico publicado en 2015

Inducible nitric oxide synthase drives mTOR pathway activation and proliferation of human melanoma by reversible nitrosylation of TSC2.

scientific article published on 07 January 2014

Late-onset megaconial myopathy in mice lacking group I Paks

artículo científico publicado en 2019

Lymphatic endothelial S1P promotes mitochondrial function and survival in naive T cells.

artículo científico publicado en 2017

MDM2 Integrates Cellular Respiration and Apoptotic Signaling through NDUFS1 and the Mitochondrial Network

artículo científico publicado en 2019

MDM2 and Mitochondrial Function: One Complex Intersection

artículo científico publicado en 2018

Mechanism of apoptosis induction by inhibition of the anti-apoptotic BCL-2 proteins

scholarly article

Mitochondrial Isolation and Real-Time Monitoring of MOMP

Mitochondrial division is requisite to RAS-induced transformation and targeted by oncogenic MAPK pathway inhibitors

artículo científico publicado en 2015

Mitochondrial metabolism in hematopoietic stem cells requires functional FOXO3.

artículo científico publicado en 2015

Mitochondrial origins of fractional control in regulated cell death

artículo científico publicado en 2019

Mitochondrial outer membrane proteins assist Bid in Bax-mediated lipidic pore formation

artículo científico publicado en 2009

Mitochondrial shape governs BAX-induced membrane permeabilization and apoptosis.

artículo científico publicado en 2014

Molecular mechanisms of cell death: recommendations of the Nomenclature Committee on Cell Death 2018.

artículo científico publicado en 2018

PB1-F2 proteins from H5N1 and 20 century pandemic influenza viruses cause immunopathology

artículo científico publicado en 2010

PUMA binding induces partial unfolding within BCL-xL to disrupt p53 binding and promote apoptosis

artículo científico publicado en 2013

PUMA couples the nuclear and cytoplasmic proapoptotic function of p53

artículo científico publicado en 2005

Pharmacologic activation of p53 elicits Bax-dependent apoptosis in the absence of transcription

artículo científico publicado en 2003

Pin1-Induced Proline Isomerization in Cytosolic p53 Mediates BAX Activation and Apoptosis

artículo científico publicado en 2015

Pivotal role for the ubiquitin Y59-E51 loop in lysine 48 polyubiquitination

artículo científico publicado en 2014

Preclinical pharmacological evaluation of a novel multiple kinase inhibitor, ON123300, in brain tumor models

artículo científico publicado en 2014

RAF/MEK/extracellular signal-related kinase pathway suppresses dendritic cell migration and traps dendritic cells in Langerhans cell histiocytosis lesions

artículo científico publicado en 2017

Sensitization to the mitochondrial pathway of apoptosis augments melanoma tumor cell responses to conventional chemotherapeutic regimens.

artículo científico publicado en 2012

Special Issue on Cell Death: Murder, mystery (and a little bit of mayhem) in Manhattan

artículo científico publicado en 2016

Sphingolipid metabolism cooperates with BAK and BAX to promote the mitochondrial pathway of apoptosis

artículo científico publicado en 2012

Survival of HER2-Positive Breast Cancer Cells: Receptor Signaling to Apoptotic Control Centers

artículo científico publicado en 2013

The BCL-2 family reunion

artículo científico publicado en 2010

The Role of BH3-Only Proteins in Tumor Cell Development, Signaling, and Treatment

artículo científico publicado en 2011

The androgen receptor represses transforming growth factor-beta signaling through interaction with Smad3.

artículo científico publicado en 2001

The deadly landscape of pro-apoptotic BCL-2 proteins in the outer mitochondrial membrane

artículo científico

The peroxisomes strike BAK: Regulation of peroxisome integrity by the Bcl-2 family

artículo científico publicado en 2017

Think We Understand the Role of DRP1 in Mitochondrial Biology? Zinc Again!

Why not add some SPARKL to your life (and death)!?

scientific article published on 17 November 2019

p53 and metabolism: Inside the TIGAR.

artículo científico publicado en 2006

p53's believe it or not: lessons on transcription-independent death

artículo científico publicado el 1 de septiembre de 2003

Lista de obras de Jerry E. Chipuk

Activation of Nrf2 Is Required for Normal and ChREBPα-Augmented Glucose-Stimulated β-Cell Proliferation

Activation of the Mitochondrial Fragmentation Protein DRP1 Correlates with BRAF(V600E) Melanoma

Aging of Antiviral CD8+ Memory T Cells Fosters Increased Survival, Metabolic Adaptations, and Lymphoid Tissue Homing

Anti-apoptotic BCL-2 proteins govern cellular outcome following B-RAF(V600E) inhibition and can be targeted to reduce resistance.

Apoptosis: Stabbed in the BAX.

B cell lymphoma-2 (BCL-2) homology domain 3 (BH3) mimetics demonstrate differential activities dependent upon the functional repertoire of pro- and anti-apoptotic BCL-2 family proteins

BAK activation is necessary and sufficient to drive ceramide synthase-dependent ceramide accumulation following inhibition of BCL2-like proteins

BAK/BAX activation and cytochrome c release assays using isolated mitochondria

BCL-2 proteins: melanoma lives on the edge

BH3 domains of BH3-only proteins differentially regulate Bax-mediated mitochondrial membrane permeabilization both directly and indirectly

BH3 domains other than Bim and Bid can directly activate Bax/Bak

Bcl-xL blocks transforming growth factor-beta 1-induced apoptosis by inhibiting cytochrome c release and not by directly antagonizing Apaf-1-dependent caspase activation in prostate epithelial cells

Born to be alive: a role for the BCL-2 family in melanoma tumor cell survival, apoptosis, and treatment

Cell death through the ages: The ICDS 25th Anniversary Meeting

Chemical inhibition of the mitochondrial division dynamin reveals its role in Bax/Bak-dependent mitochondrial outer membrane permeabilization

Connected to death: the (unexpurgated) mitochondrial pathway of apoptosis

Death upon a kiss: mitochondrial outer membrane composition and organelle communication govern sensitivity to BAK/BAX-dependent apoptosis

Direct activation of Bax by p53 mediates mitochondrial membrane permeabilization and apoptosis

Disruption of mitochondrial electron transport chain function potentiates the pro-apoptotic effects of MAPK inhibition

Dissecting p53-dependent apoptosis.

Do inducers of apoptosis trigger caspase-independent cell death?

Dual suppression of inner and outer mitochondrial membrane functions augments apoptotic responses to oncogenic MAPK inhibition

Essential versus accessory aspects of cell death: recommendations of the NCCD 2015.

Examining BCL-2 family function with large unilamellar vesicles

FBXW7 regulates a mitochondrial transcription program by modulating MITF.

From zero to sixty: cell death signaling in the city that never sleeps

GM-CSF controls nonlymphoid tissue dendritic cell homeostasis but is dispensable for the differentiation of inflammatory dendritic cells

Genetically defining the mechanism of Puma- and Bim-induced apoptosis

Getting away with murder: how does the BCL-2 family of proteins kill with immunity?

How do BCL-2 proteins induce mitochondrial outer membrane permeabilization?

How do I kill thee? Let me count the ways: p53 regulates PARP-1 dependent necrosis

Identification and characterization of a novel rat ov-serpin family member, trespin

Immune biomarkers are more accurate in prediction of survival in ulcerated than in non-ulcerated primary melanomas

Inducible nitric oxide synthase drives mTOR pathway activation and proliferation of human melanoma by reversible nitrosylation of TSC2.

Late-onset megaconial myopathy in mice lacking group I Paks

Lymphatic endothelial S1P promotes mitochondrial function and survival in naive T cells.

MDM2 Integrates Cellular Respiration and Apoptotic Signaling through NDUFS1 and the Mitochondrial Network

MDM2 and Mitochondrial Function: One Complex Intersection

Mechanism of apoptosis induction by inhibition of the anti-apoptotic BCL-2 proteins

Mitochondrial Isolation and Real-Time Monitoring of MOMP

Mitochondrial division is requisite to RAS-induced transformation and targeted by oncogenic MAPK pathway inhibitors

Mitochondrial metabolism in hematopoietic stem cells requires functional FOXO3.

Mitochondrial origins of fractional control in regulated cell death

Mitochondrial outer membrane proteins assist Bid in Bax-mediated lipidic pore formation

Mitochondrial shape governs BAX-induced membrane permeabilization and apoptosis.

Molecular mechanisms of cell death: recommendations of the Nomenclature Committee on Cell Death 2018.

PB1-F2 proteins from H5N1 and 20 century pandemic influenza viruses cause immunopathology

PUMA binding induces partial unfolding within BCL-xL to disrupt p53 binding and promote apoptosis

PUMA couples the nuclear and cytoplasmic proapoptotic function of p53

Pharmacologic activation of p53 elicits Bax-dependent apoptosis in the absence of transcription

Pin1-Induced Proline Isomerization in Cytosolic p53 Mediates BAX Activation and Apoptosis

Pivotal role for the ubiquitin Y59-E51 loop in lysine 48 polyubiquitination

Preclinical pharmacological evaluation of a novel multiple kinase inhibitor, ON123300, in brain tumor models

RAF/MEK/extracellular signal-related kinase pathway suppresses dendritic cell migration and traps dendritic cells in Langerhans cell histiocytosis lesions

Sensitization to the mitochondrial pathway of apoptosis augments melanoma tumor cell responses to conventional chemotherapeutic regimens.

Special Issue on Cell Death: Murder, mystery (and a little bit of mayhem) in Manhattan

Sphingolipid metabolism cooperates with BAK and BAX to promote the mitochondrial pathway of apoptosis

Survival of HER2-Positive Breast Cancer Cells: Receptor Signaling to Apoptotic Control Centers

The BCL-2 family reunion

The Role of BH3-Only Proteins in Tumor Cell Development, Signaling, and Treatment

The androgen receptor represses transforming growth factor-beta signaling through interaction with Smad3.

The deadly landscape of pro-apoptotic BCL-2 proteins in the outer mitochondrial membrane

The peroxisomes strike BAK: Regulation of peroxisome integrity by the Bcl-2 family

Think We Understand the Role of DRP1 in Mitochondrial Biology? Zinc Again!

Why not add some SPARKL to your life (and death)!?

p53 and metabolism: Inside the TIGAR.

p53's believe it or not: lessons on transcription-independent death