Lista de obras - Filip Lardon - Dominio Público Uruguay

A Comparison of Cell-Free DNA Isolation Kits: Isolation and Quantification of Cell-Free DNA in Plasma.

artículo científico publicado en 2016

A review of the most promising biomarkers in colorectal cancer: one step closer to targeted therapy

artículo científico publicado en 2010

APR-246 (PRIMA-1(MET)) strongly synergizes with AZD2281 (olaparib) induced PARP inhibition to induce apoptosis in non-small cell lung cancer cell lines

artículo científico publicado en 2016

Anti-epidermal growth factor receptor therapy in head and neck squamous cell carcinoma: focus on potential molecular mechanisms of drug resistance

artículo científico

CD70: An emerging target in cancer immunotherapy

artículo científico

Can cervical cancer screening be stopped at 50? The prevalence of HPV in elderly women.

artículo científico publicado en 2004

Cell cycle effect of gemcitabine and its role in the radiosensitizing mechanism in vitro

artículo científico publicado en 2003

Cell cycle effects of vinflunine, the most recent promising Vinca alkaloid, and its interaction with radiation, in vitro

artículo científico publicado en 2005

Chemoradiation interactions under reduced oxygen conditions: Cellular characteristics of an in vitro model

artículo científico publicado en 2009

Circulating Cell-Free DNA and RNA Analysis as Liquid Biopsy: Optimal Centrifugation Protocol.

artículo científico publicado en 2019

Circulating cell-free nucleic acids and platelets as a liquid biopsy in the provision of personalized therapy for lung cancer patients

artículo científico publicado en 2016

Cold Atmospheric Plasma-Treated PBS Eliminates Immunosuppressive Pancreatic Stellate Cells and Induces Immunogenic Cell Death of Pancreatic Cancer Cells

scientific article published on 19 October 2019

Combined Pap and HPV testing in primary screening for cervical abnormalities: should HPV detection be delayed until age 35?

artículo científico publicado en 2005

Combined modality therapy of gemcitabine and radiation

artículo científico publicado en 2005

Comparative analysis of dynamic cell viability, migration and invasion assessments by novel real-time technology and classic endpoint assays

artículo científico publicado en 2012

Comparative study of the radiosensitizing and cell cycle effects of vinflunine and vinorelbine, in vitro

artículo científico publicado en 2008

Comparison of three commonly used PCR-based techniques to analyze MSI status in sporadic colorectal cancer

artículo científico publicado en 2006

Concomitant Chlamydia trachomatis and human papilloma virus infection cannot be attributed solely to sexual behaviour.

artículo científico publicado en 2004

Counting clonogenic assays from normoxic and anoxic irradiation experiments manually or by using densitometric software

artículo científico publicado en 2010

Decrease in nucleoside diphosphate kinase (NDPK/nm23) expression during hematopoietic maturation.

artículo científico publicado en 1998

Decreased expression of ABAT and STC2 hallmarks ER-positive inflammatory breast cancer and endocrine therapy resistance in advanced disease

artículo científico publicado en 2015

Deep sequencing of the TP53 gene reveals a potential risk allele for non-small cell lung cancer and supports the negative prognostic value of TP53 variants.

artículo científico publicado en 2017

Detection of HPV and the role of p16INK4A overexpression as a surrogate marker for the presence of functional HPV oncoprotein E7 in colorectal cancer

artículo científico publicado en 2010

Detection of microsatellite instability in colorectal cancer using an alternative multiplex assay of quasi-monomorphic mononucleotide markers.

artículo científico publicado en 2008

Dual Targeting of Epidermal Growth Factor Receptor and HER3 by MEHD7945A as Monotherapy or in Combination with Cisplatin Partially Overcomes Cetuximab Resistance in Head and Neck Squamous Cell Carcinoma Cell Lines.

artículo científico publicado en 2017

Effect of indomethacin on cell cycle dependent cyclic AMP fluxes in tobacco BY-2 cells.

artículo científico publicado en 1998

Efficacy Screening of Gloriosa Superba Extracts in a Murine Pancreatic Cancer Model Using (18)F-FDG PET/CT for Monitoring Treatment Response

artículo científico publicado en 2016

Expression analysis on archival material revisited: isolation and quantification of RNA extracted from FFPE samples

artículo científico

Expression analysis on archival material: comparison of 5 commercially available RNA isolation kits for FFPE material

artículo científico

Feasibility of collecting self-sampled vaginal swabs by mail: quantity and quality of genomic DNA

artículo científico publicado en 2009

Further mechanistic unravelling of the influence of the cell cycle effects on the radiosensitising mechanism of vinflunine, in vitro

artículo científico publicado en 2007

Generation of dendritic cells from bone marrow progenitors using GM-CSF, TNF-alpha, and additional cytokines: antagonistic effects of IL-4 and IFN-gamma and selective involvement of TNF-alpha receptor-1

scientific article published on 01 August 1997

HPV in cervix and vagina.

artículo científico publicado en 2004

Highly efficient gene delivery by mRNA electroporation in human hematopoietic cells: superiority to lipofection and passive pulsing of mRNA and to electroporation of plasmid cDNA for tumor antigen loading of dendritic cells

artículo científico publicado en 2001

Hypoxia-Induced Cisplatin Resistance in Non-Small Cell Lung Cancer Cells Is Mediated by HIF-1α and Mutant p53 and Can Be Overcome by Induction of Oxidative Stress.

artículo científico publicado en 2018

Immune Checkpoint Modulation in Colorectal Cancer: What's New and What to Expect

artículo científico publicado en 2015

In vitro and in vivo investigations on the antitumour activity of Chelidonium majus.

artículo científico publicado en 2015

In vitro interaction between ecteinascidin 743 (ET-743) and radiation, in relation to its cell cycle effects

artículo científico publicado en 2003

In vitro study on the schedule-dependency of the interaction between pemetrexed, gemcitabine and irradiation in non-small cell lung cancer and head and neck cancer cells

artículo científico publicado en 2010

Interferon gamma selectively inhibits very primitive CD342+CD38- and not more mature CD34+CD38+ human hematopoietic progenitor cells

artículo científico publicado en 1994

Interferon-gamma and interleukin-4 reciprocally regulate the production of monocytes/macrophages and neutrophils through a direct effect on committed monopotential bone marrow progenitor cells

artículo científico publicado en 1993

Interleukin-15 stimulates natural killer cell-mediated killing of both human pancreatic cancer and stellate cells

artículo científico publicado en 2017

KRAS mutation detection and prognostic potential in sporadic colorectal cancer using high-resolution melting analysis

artículo científico publicado en 2010

MDM2 SNP309 and SNP285 Act as Negative Prognostic Markers for Non-small Cell Lung Cancer Adenocarcinoma Patients.

artículo científico publicado en 2017

Microsatellite instability in sporadic colon carcinomas has no independent prognostic value in a Belgian study population

article

Monitoring EGFR TKI resistance in real time using ddPCR-based liquid biopsy: a case report

scientific article published on 31 May 2018

Nonviral transfection of distinct types of human dendritic cells: high-efficiency gene transfer by electroporation into hematopoietic progenitor- but not monocyte-derived dendritic cells

artículo científico publicado en 1998

Overcoming Intrinsic and Acquired Cetuximab Resistance in RAS Wild-Type Colorectal Cancer: An In Vitro Study on the Expression of HER Receptors and the Potential of Afatinib

artículo científico publicado en 2019

Overcoming cetuximab resistance in HNSCC: the role of AURKB and DUSP proteins

artículo científico publicado en 2014

Pharmacological levels of Withaferin A (Withania somnifera) trigger clinically relevant anticancer effects specific to triple negative breast cancer cells

artículo científico publicado en 2014

Phase II multicenter clinical trial of pulmonary metastasectomy and isolated lung perfusion with melphalan in patients with resectable lung metastases

artículo científico publicado en 2014

Poly(I:C) primes primary human glioblastoma cells for an immune response invigorated by PD-L1 blockade

artículo científico publicado en 2017

Preclinical and clinical studies on afatinib in monotherapy and in combination regimens: Potential impact in colorectal cancer

artículo científico publicado en 2016

Preclinical data on the combination of cisplatin and anti-CD70 therapy in non-small cell lung cancer as an excellent match in the era of combination therapy.

artículo científico publicado en 2017

Prevalence of human papillomavirus in elderly women with cervical cancer

artículo científico publicado en 2001

Primary skeletal muscle myoblasts from chronic heart failure patients exhibit loss of anti-inflammatory and proliferative activity.

artículo científico publicado en 2016

Probiotics enhance the clearance of human papillomavirus-related cervical lesions: a prospective controlled pilot study.

artículo científico publicado en 2013

Prospective study of intratumoral microvessel density, p53 expression and survival in colorectal cancer

artículo científico publicado en 1999

RANK/RANKL signaling inhibition may improve the effectiveness of checkpoint blockade in cancer treatment

artículo científico publicado en 2018

Radiosensitization of Non-Small Cell Lung Cancer Cells by the Plk1 Inhibitor Volasertib Is Dependent on the p53 Status

artículo científico publicado en 2019

Retention of the in vitro radiosensitizing potential of gemcitabine under anoxic conditions, in p53 wild-type and p53-deficient non-small-cell lung carcinoma cells

artículo científico publicado en 2011

Review: implications of in vitro research on the effect of radiotherapy and chemotherapy under hypoxic conditions.

artículo científico publicado en 2007

Role of cell cycle perturbations in the combination therapy of chemotherapeutic agents and radiation

scientific article published on September 2010

Selective pulmonary artery perfusion with melphalan is equal to isolated lung perfusion but superior to intravenous melphalan for the treatment of sarcoma lung metastases in a rodent model.

artículo científico publicado en 2012

Simultaneous targeting of EGFR, HER2, and HER4 by afatinib overcomes intrinsic and acquired cetuximab resistance in head and neck squamous cell carcinoma cell lines

artículo científico publicado en 2018

Specialized Blood Collection Tubes for Liquid Biopsy: Improving the Pre-analytical Conditions

scientific article published on 01 February 2020

Specific checkpoints regulate plant cell cycle progression in response to oxidative stress

article

Spotlight on Volasertib: Preclinical and Clinical Evaluation of a Promising Plk1 Inhibitor

artículo científico publicado en 2016

Synthesis and in vivo preclinical evaluation of an (18)F labeled uPA inhibitor as a potential PET imaging agent

artículo científico publicado en 2014

TP53 and MDM2 genetic alterations in non-small cell lung cancer: Evaluating their prognostic and predictive value

artículo científico publicado en 2015

The Benefit of Reactivating p53 under MAPK Inhibition on the Efficacy of Radiotherapy in Melanoma

artículo científico publicado en 2019

The MDM2-inhibitor Nutlin-3 synergizes with cisplatin to induce p53 dependent tumor cell apoptosis in non-small cell lung cancer

artículo científico publicado en 2015

The Prevalence of the Human Papillomavirus in Cervix and Vagina in Low-risk and High-risk Populations

artículo científico publicado en 2004

The Role of c-Met as a Biomarker and Player in Innate and Acquired Resistance in Non-Small-Cell Lung Cancer: Two New Mutations Warrant Further Studies

scientific article published on 04 December 2019

The effect of vancomycin and teicoplanin on normal human bone marrow progenitor cells

artículo científico publicado en 1992

The interaction between ER and NFκB in resistance to endocrine therapy.

artículo científico publicado en 2012

The presence of Y chromosomal deoxyribonucleic acid in the female vaginal swab: possible implications for human papillomavirus testing

artículo científico publicado en 2010

The radiosensitising effect of difluorodeoxyuridine, a metabolite of gemcitabine, in vitro

artículo científico publicado en 2005

The radiosensitising effect of gemcitabine and its main metabolite dFdU under low oxygen conditions is in vitro not dependent on functional HIF-1 protein

artículo científico publicado en 2014

The radiosensitising effect of gemcitabine and the influence of the rescue agent amifostine in vitro

artículo científico publicado en 2003

The relation between deoxycytidine kinase activity and the radiosensitising effect of gemcitabine in eight different human tumour cell lines

artículo científico publicado en 2006

The role of apoptotic cell death in the radiosensitising effect of gemcitabine

artículo científico publicado en 2009

Towards Prognostic Profiling of Non-Small Cell Lung Cancer: New Perspectives on the Relevance of Polo-Like Kinase 1 Expression, the TP53 Mutation Status and Hypoxia

artículo científico publicado en 2017

Tumor cells and tumor-associated macrophages: secreted proteins as potential targets for therapy.

artículo científico publicado en 2011

Tumor infiltrating lymphocytes: an intriguing player in the survival of colorectal cancer patients

artículo científico publicado en 2010

Tumor necrosis factor alpha is a potent synergistic factor for the proliferation of primitive human hematopoietic progenitor cells and induces resistance to transforming growth factor beta but not to interferon gamma

artículo científico publicado en 1996

Unraveling the mechanism of radiosensitization by gemcitabine: the role of TP53.

artículo científico publicado en 2005

Unveiling a CD70-positive subset of cancer-associated fibroblasts marked by pro-migratory activity and thriving regulatory T cell accumulation

scientific article published on 19 March 2018

mRNA-electroporated mature dendritic cells retain transgene expression, phenotypical properties and stimulatory capacity after cryopreservation

artículo científico publicado en 2002

Lista de obras de Filip Lardon

A Comparison of Cell-Free DNA Isolation Kits: Isolation and Quantification of Cell-Free DNA in Plasma.

A review of the most promising biomarkers in colorectal cancer: one step closer to targeted therapy

APR-246 (PRIMA-1(MET)) strongly synergizes with AZD2281 (olaparib) induced PARP inhibition to induce apoptosis in non-small cell lung cancer cell lines

Anti-epidermal growth factor receptor therapy in head and neck squamous cell carcinoma: focus on potential molecular mechanisms of drug resistance

CD70: An emerging target in cancer immunotherapy

Can cervical cancer screening be stopped at 50? The prevalence of HPV in elderly women.

Cell cycle effect of gemcitabine and its role in the radiosensitizing mechanism in vitro

Cell cycle effects of vinflunine, the most recent promising Vinca alkaloid, and its interaction with radiation, in vitro

Chemoradiation interactions under reduced oxygen conditions: Cellular characteristics of an in vitro model

Circulating Cell-Free DNA and RNA Analysis as Liquid Biopsy: Optimal Centrifugation Protocol.

Circulating cell-free nucleic acids and platelets as a liquid biopsy in the provision of personalized therapy for lung cancer patients

Cold Atmospheric Plasma-Treated PBS Eliminates Immunosuppressive Pancreatic Stellate Cells and Induces Immunogenic Cell Death of Pancreatic Cancer Cells

Combined Pap and HPV testing in primary screening for cervical abnormalities: should HPV detection be delayed until age 35?

Combined modality therapy of gemcitabine and radiation

Comparative analysis of dynamic cell viability, migration and invasion assessments by novel real-time technology and classic endpoint assays

Comparative study of the radiosensitizing and cell cycle effects of vinflunine and vinorelbine, in vitro

Comparison of three commonly used PCR-based techniques to analyze MSI status in sporadic colorectal cancer

Concomitant Chlamydia trachomatis and human papilloma virus infection cannot be attributed solely to sexual behaviour.

Counting clonogenic assays from normoxic and anoxic irradiation experiments manually or by using densitometric software

Decrease in nucleoside diphosphate kinase (NDPK/nm23) expression during hematopoietic maturation.

Decreased expression of ABAT and STC2 hallmarks ER-positive inflammatory breast cancer and endocrine therapy resistance in advanced disease

Deep sequencing of the TP53 gene reveals a potential risk allele for non-small cell lung cancer and supports the negative prognostic value of TP53 variants.

Detection of HPV and the role of p16INK4A overexpression as a surrogate marker for the presence of functional HPV oncoprotein E7 in colorectal cancer

Detection of microsatellite instability in colorectal cancer using an alternative multiplex assay of quasi-monomorphic mononucleotide markers.

Dual Targeting of Epidermal Growth Factor Receptor and HER3 by MEHD7945A as Monotherapy or in Combination with Cisplatin Partially Overcomes Cetuximab Resistance in Head and Neck Squamous Cell Carcinoma Cell Lines.

Effect of indomethacin on cell cycle dependent cyclic AMP fluxes in tobacco BY-2 cells.

Efficacy Screening of Gloriosa Superba Extracts in a Murine Pancreatic Cancer Model Using (18)F-FDG PET/CT for Monitoring Treatment Response

Expression analysis on archival material revisited: isolation and quantification of RNA extracted from FFPE samples

Expression analysis on archival material: comparison of 5 commercially available RNA isolation kits for FFPE material

Feasibility of collecting self-sampled vaginal swabs by mail: quantity and quality of genomic DNA

Further mechanistic unravelling of the influence of the cell cycle effects on the radiosensitising mechanism of vinflunine, in vitro

Generation of dendritic cells from bone marrow progenitors using GM-CSF, TNF-alpha, and additional cytokines: antagonistic effects of IL-4 and IFN-gamma and selective involvement of TNF-alpha receptor-1

HPV in cervix and vagina.

Highly efficient gene delivery by mRNA electroporation in human hematopoietic cells: superiority to lipofection and passive pulsing of mRNA and to electroporation of plasmid cDNA for tumor antigen loading of dendritic cells

Hypoxia-Induced Cisplatin Resistance in Non-Small Cell Lung Cancer Cells Is Mediated by HIF-1α and Mutant p53 and Can Be Overcome by Induction of Oxidative Stress.

Immune Checkpoint Modulation in Colorectal Cancer: What's New and What to Expect

In vitro and in vivo investigations on the antitumour activity of Chelidonium majus.

In vitro interaction between ecteinascidin 743 (ET-743) and radiation, in relation to its cell cycle effects

In vitro study on the schedule-dependency of the interaction between pemetrexed, gemcitabine and irradiation in non-small cell lung cancer and head and neck cancer cells

Interferon gamma selectively inhibits very primitive CD342+CD38- and not more mature CD34+CD38+ human hematopoietic progenitor cells

Interferon-gamma and interleukin-4 reciprocally regulate the production of monocytes/macrophages and neutrophils through a direct effect on committed monopotential bone marrow progenitor cells

Interleukin-15 stimulates natural killer cell-mediated killing of both human pancreatic cancer and stellate cells

KRAS mutation detection and prognostic potential in sporadic colorectal cancer using high-resolution melting analysis

MDM2 SNP309 and SNP285 Act as Negative Prognostic Markers for Non-small Cell Lung Cancer Adenocarcinoma Patients.

Microsatellite instability in sporadic colon carcinomas has no independent prognostic value in a Belgian study population

Monitoring EGFR TKI resistance in real time using ddPCR-based liquid biopsy: a case report

Nonviral transfection of distinct types of human dendritic cells: high-efficiency gene transfer by electroporation into hematopoietic progenitor- but not monocyte-derived dendritic cells

Overcoming Intrinsic and Acquired Cetuximab Resistance in RAS Wild-Type Colorectal Cancer: An In Vitro Study on the Expression of HER Receptors and the Potential of Afatinib

Overcoming cetuximab resistance in HNSCC: the role of AURKB and DUSP proteins

Pharmacological levels of Withaferin A (Withania somnifera) trigger clinically relevant anticancer effects specific to triple negative breast cancer cells

Phase II multicenter clinical trial of pulmonary metastasectomy and isolated lung perfusion with melphalan in patients with resectable lung metastases

Poly(I:C) primes primary human glioblastoma cells for an immune response invigorated by PD-L1 blockade

Preclinical and clinical studies on afatinib in monotherapy and in combination regimens: Potential impact in colorectal cancer

Preclinical data on the combination of cisplatin and anti-CD70 therapy in non-small cell lung cancer as an excellent match in the era of combination therapy.

Prevalence of human papillomavirus in elderly women with cervical cancer

Primary skeletal muscle myoblasts from chronic heart failure patients exhibit loss of anti-inflammatory and proliferative activity.

Probiotics enhance the clearance of human papillomavirus-related cervical lesions: a prospective controlled pilot study.

Prospective study of intratumoral microvessel density, p53 expression and survival in colorectal cancer

RANK/RANKL signaling inhibition may improve the effectiveness of checkpoint blockade in cancer treatment

Radiosensitization of Non-Small Cell Lung Cancer Cells by the Plk1 Inhibitor Volasertib Is Dependent on the p53 Status

Retention of the in vitro radiosensitizing potential of gemcitabine under anoxic conditions, in p53 wild-type and p53-deficient non-small-cell lung carcinoma cells

Review: implications of in vitro research on the effect of radiotherapy and chemotherapy under hypoxic conditions.

Role of cell cycle perturbations in the combination therapy of chemotherapeutic agents and radiation

Selective pulmonary artery perfusion with melphalan is equal to isolated lung perfusion but superior to intravenous melphalan for the treatment of sarcoma lung metastases in a rodent model.

Simultaneous targeting of EGFR, HER2, and HER4 by afatinib overcomes intrinsic and acquired cetuximab resistance in head and neck squamous cell carcinoma cell lines

Specialized Blood Collection Tubes for Liquid Biopsy: Improving the Pre-analytical Conditions

Specific checkpoints regulate plant cell cycle progression in response to oxidative stress

Spotlight on Volasertib: Preclinical and Clinical Evaluation of a Promising Plk1 Inhibitor

Synthesis and in vivo preclinical evaluation of an (18)F labeled uPA inhibitor as a potential PET imaging agent

TP53 and MDM2 genetic alterations in non-small cell lung cancer: Evaluating their prognostic and predictive value

The Benefit of Reactivating p53 under MAPK Inhibition on the Efficacy of Radiotherapy in Melanoma

The MDM2-inhibitor Nutlin-3 synergizes with cisplatin to induce p53 dependent tumor cell apoptosis in non-small cell lung cancer

The Prevalence of the Human Papillomavirus in Cervix and Vagina in Low-risk and High-risk Populations

The Role of c-Met as a Biomarker and Player in Innate and Acquired Resistance in Non-Small-Cell Lung Cancer: Two New Mutations Warrant Further Studies

The effect of vancomycin and teicoplanin on normal human bone marrow progenitor cells

The interaction between ER and NFκB in resistance to endocrine therapy.

The presence of Y chromosomal deoxyribonucleic acid in the female vaginal swab: possible implications for human papillomavirus testing

The radiosensitising effect of difluorodeoxyuridine, a metabolite of gemcitabine, in vitro

The radiosensitising effect of gemcitabine and its main metabolite dFdU under low oxygen conditions is in vitro not dependent on functional HIF-1 protein