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Lista de obras de Julie Forman-Kay

15N H/D-SOLEXSY experiment for accurate measurement of amide solvent exchange rates: application to denatured drkN SH3.

artículo científico publicado en 2010

19F NMR studies of solvent exposure and peptide binding to an SH3 domain

artículo científico publicado en 2006

1H and 15N resonance assignments and secondary structure of the human thioredoxin C62A, C69A, C73A mutant

artículo científico publicado en 1992

A "three-pronged" binding mechanism for the SAP/SH2D1A SH2 domain: structural basis and relevance to the XLP syndrome

artículo científico publicado en 2002

A New Phase in ALS Research

artículo científico publicado en 2016

A hidden competitive advantage of disorder

artículo científico publicado en 2017

A proton nuclear magnetic resonance assignment and secondary structure determination of recombinant human thioredoxin.

artículo científico publicado en 1989

A simple in vivo assay for increased protein solubility

artículo científico publicado en 1999

Affinity and specificity of interactions between Nedd4 isoforms and the epithelial Na+ channel

artículo científico publicado en 2003

Allosteric coupling between the intracellular coupling helix 4 and regulatory sites of the first nucleotide-binding domain of CFTR

artículo científico publicado en 2013

An allosteric conduit facilitates dynamic multisite substrate recognition by the SCF(Cdc4) ubiquitin ligase

artículo científico publicado en 2017

An evolutionary switch in ND2 enables Src kinase regulation of NMDA receptors

artículo científico publicado en 2017

An expanded WW domain recognition motif revealed by the interaction between Smad7 and the E3 ubiquitin ligase Smurf2

artículo científico publicado en 2006

Analysis of deuterium relaxation-derived methyl axis order parameters and correlation with local structure

artículo científico publicado en 1999

Aromatic and methyl NOEs highlight hydrophobic clustering in the unfolded state of an SH3 domain

artículo científico publicado en 2003

Atomic-level characterization of disordered protein ensembles

artículo científico publicado en 2007

Autoinhibition of the HECT-type ubiquitin ligase Smurf2 through its C2 domain

artículo científico publicado en 2007

Backbone 1H and 15N resonance assignments of the N-terminal SH3 domain of drk in folded and unfolded states using enhanced-sensitivity pulsed field gradient NMR techniques

artículo científico publicado en 1994

Backbone dynamics of a free and phosphopeptide-complexed Src homology 2 domain studied by 15N NMR relaxation

artículo científico publicado en 1994

Binding screen for cystic fibrosis transmembrane conductance regulator correctors finds new chemical matter and yields insights into cystic fibrosis therapeutic strategy

artículo científico publicado en 2015

CFTR regulatory region interacts with NBD1 predominantly via multiple transient helices

scientific article published on 29 July 2007

Calculation of ensembles of structures representing the unfolded state of an SH3 domain.

artículo científico publicado en 2001

Calculation of residual dipolar couplings from disordered state ensembles using local alignment

artículo científico publicado en 2008

Characterization of disordered proteins with ENSEMBLE.

artículo científico publicado en 2012

Characterization of the PilN, PilO and PilP type IVa pilus subcomplex ⬇️

artículo científico publicado el 18 de noviembre de 2011

Characterization of the hydrodynamic properties of the folding transition state of an SH3 domain by magnetization transfer NMR spectroscopy

artículo científico publicado en 2006

Characterization of the phosphotyrosine-binding domain of the Drosophila Shc protein

artículo científico publicado en 1996

Clinical presentation and molecular basis of congenital antithrombin deficiency in children: a cohort study

scientific article published on 29 March 2014

Comparative roles of charge, π, and hydrophobic interactions in sequence-dependent phase separation of intrinsically disordered proteins

artículo científico publicado en 2020

Comparison of the backbone dynamics of a folded and an unfolded SH3 domain existing in equilibrium in aqueous buffer.

artículo científico publicado en 1995

Composite low affinity interactions dictate recognition of the cyclin-dependent kinase inhibitor Sic1 by the SCFCdc4 ubiquitin ligase

artículo científico publicado en 2012

Comprehensive NOE characterization of a partially folded large fragment of staphylococcal nuclease Delta131Delta, using NMR methods with improved resolution

artículo científico publicado en 1997

Conformational changes relevant to channel activity and folding within the first nucleotide binding domain of the cystic fibrosis transmembrane conductance regulator

artículo científico publicado en 2012

Conformations of a Metastable SH3 Domain Characterized by smFRET and an Excluded-Volume Polymer Model

artículo científico publicado en 2016

Congenital chloride-losing diarrhea causing mutations in the STAS domain result in misfolding and mistrafficking of SLC26A3.

artículo científico publicado en 2008

Contributions to protein entropy and heat capacity from bond vector motions measured by NMR spin relaxation

artículo científico publicado en 1997

Cooperative interactions and a non-native buried Trp in the unfolded state of an SH3 domain

artículo científico publicado en 2002

Correlation between binding and dynamics at SH2 domain interfaces

article

Correlation between dynamics and high affinity binding in an SH2 domain interaction

artículo científico publicado en 1996

Coupling of tandem Smad ubiquitination regulatory factor (Smurf) WW domains modulates target specificity

artículo científico publicado en 2010

Deletion of Phenylalanine 508 in the First Nucleotide-binding Domain of the Cystic Fibrosis Transmembrane Conductance Regulator Increases Conformational Exchange and Inhibits Dimerization

artículo científico publicado en 2015

Development and characterization of synthetic antibodies binding to the cystic fibrosis conductance regulator

artículo científico publicado en 2016

Differential dynamic engagement within 24 SH3 domain: peptide complexes revealed by co-linear chemical shift perturbation analysis

artículo científico publicado en 2012

Direct Binding of the Corrector VX-809 to Human CFTR NBD1: Evidence of an Allosteric Coupling between the Binding Site and the NBD1:CL4 Interface

artículo científico publicado en 2017

Distribution of molecular size within an unfolded state ensemble using small-angle X-ray scattering and pulse field gradient NMR techniques

artículo científico publicado en 2002

Dramatic stabilization of an SH3 domain by a single substitution: roles of the folded and unfolded states.

artículo científico publicado en 2001

Dynamic Protein Interaction Networks and New Structural Paradigms in Signaling

artículo científico publicado en 2016

Dynamic equilibrium engagement of a polyvalent ligand with a single-site receptor

artículo científico publicado en 2008

Dynamics intrinsic to cystic fibrosis transmembrane conductance regulator function and stability

artículo científico publicado en 2013

Ensemble modeling of protein disordered states: Experimental restraint contributions and validation ⬇️

artículo científico publicado el 17 de noviembre de 2011

Entropy and Information within Intrinsically Disordered Protein Regions

scientific article published on 06 July 2019

Finding Our Way in the Dark Proteome

artículo científico publicado en 2016

Folding of an intrinsically disordered protein by phosphorylation as a regulatory switch

artículo científico publicado en 2015

From sequence and forces to structure, function, and evolution of intrinsically disordered proteins

artículo científico publicado en 2013

High populations of non-native structures in the denatured state are compatible with the formation of the native folded state

artículo científico publicado en 1998

High-affinity binding of the Drosophila Numb phosphotyrosine-binding domain to peptides containing a Gly-Pro-(p)Tyr motif

artículo científico publicado en 1997

Hydration and packing along the folding pathway of SH3 domains by pressure-dependent NMR.

artículo científico publicado en 2006

IDPConformerGenerator: A Flexible Software Suite for Sampling the Conformational Space of Disordered Protein States

artículo científico publicado en 2022

Identification and characterization of human genes encoding Hprp3p and Hprp4p, interacting components of the spliceosome

artículo científico publicado en 1997

Improved structural characterizations of the drkN SH3 domain unfolded state suggest a compact ensemble with native-like and non-native structure

artículo científico publicado en 2007

In support of the BMRB.

artículo científico publicado en 2012

Interaction of the eukaryotic initiation factor 4E with 4E-BP2 at a dynamic bipartite interface

artículo científico publicado en 2013

Interactions between the three CIN85 SH3 domains and ubiquitin: implications for CIN85 ubiquitination

artículo científico publicado en 2008

Interplay of buried histidine protonation and protein stability in prion misfolding

artículo científico publicado en 2017

Liquid-liquid phase separation in cellular signaling systems

artículo científico publicado en 2016

Measurement of side-chain carboxyl pK(a) values of glutamate and aspartate residues in an unfolded protein by multinuclear NMR spectroscopy

artículo científico publicado en 2002

Measuring pK(a) values in protein folding transition state ensembles by NMR spectroscopy

artículo científico publicado en 2005

Megakaryocyte and platelet abnormalities in a patient with a W33C mutation in the conserved SH3-like domain of myosin heavy chain IIA.

artículo científico publicado en 2009

Modulation of Intrinsically Disordered Protein Function by Post-translational Modifications

artículo científico publicado en 2016

Molecular structural analysis of a novel and de-novo mutation in the SERPINC1 gene associated with type 1 antithrombin deficiency.

artículo científico publicado en 2016

Multiple modes of peptide recognition by the PTB domain of the cell fate determinant Numb

artículo científico publicado en 2000

NMR Experiments for Studies of Dilute and Condensed Protein Phases: Application to the Phase-Separating Protein CAPRIN1

artículo científico publicado en 2020

NMR characterization of copper-binding domains 4-6 of ATP7B .

artículo científico publicado en 2010

NMR dynamics-derived insights into the binding properties of a peptide interacting with an SH2 domain

artículo científico publicado en 2005

NMR evidence for differential phosphorylation-dependent interactions in WT and DeltaF508 CFTR.

artículo científico publicado en 2009

NMR spectroscopy to study the dynamics and interactions of CFTR.

artículo científico publicado en 2011

NMR structure of neuromedin C, a neurotransmitter with an amino terminal CuII-, NiII-binding (ATCUN) motif

artículo científico publicado en 1997

NMR studies of tandem WW domains of Nedd4 in complex with a PY motif-containing region of the epithelial sodium channel

scientific journal article

NOE data demonstrating a compact unfolded state for an SH3 domain under non-denaturing conditions.

artículo científico publicado en 1999

Non-cooperative 4E-BP2 folding with exchange between eIF4E-binding and binding-incompatible states tunes cap-dependent translation inhibition

scientific article published on 19 June 2020

Nuclear magnetic resonance structure of an SH2 domain of phospholipase C-gamma 1 complexed with a high affinity binding peptide

artículo científico publicado en 1994

Oxidative Inhibition of Pbp1 Phase Separation

artículo científico publicado en 2019

Oxygen as a paramagnetic probe of clustering and solvent exposure in folded and unfolded states of an SH3 domain

artículo científico publicado en 2007

Phase transition of a disordered nuage protein generates environmentally responsive membraneless organelles

artículo científico publicado en 2015

Phenotypic profiling of CFTR modulators in patient-derived respiratory epithelia

artículo científico publicado en 2017

Phospho-dependent phase separation of FMRP and CAPRIN1 recapitulates regulation of translation and deadenylation

scientific article published on 01 August 2019

Phosphoregulated FMRP phase separation models activity-dependent translation through bidirectional control of mRNA granule formation

artículo científico publicado en 2019

Phosphorylation-dependent 14-3-3 protein interactions regulate CFTR biogenesis

artículo científico publicado en 2012

Pi-Pi contacts are an overlooked protein feature relevant to phase separation

artículo científico publicado en 2018

Polyelectrostatic interactions of disordered ligands suggest a physical basis for ultrasensitivity

artículo científico publicado en 2007

Probing the diverse landscape of protein flexibility and binding ⬇️

artículo científico publicado el 20 de septiembre de 2012

Protein dynamics and conformational disorder in molecular recognition

scientific article published on March 2010

Proteome-wide signatures of function in highly diverged intrinsically disordered regions

artículo científico publicado en 2019

Regulatory R region of the CFTR chloride channel is a dynamic integrator of phospho-dependent intra- and intermolecular interactions

artículo científico publicado en 2013

Relationship between electrostatics and redox function in human thioredoxin: characterization of pH titration shifts using two-dimensional homo- and heteronuclear NMR.

artículo científico publicado en 1992

Role of CBS and Bateman Domains in Phosphorylation-Dependent Regulation of a CLC Anion Channel

artículo científico publicado en 2016

Sensitivity of secondary structure propensities to sequence differences between alpha- and gamma-synuclein: implications for fibrillation

artículo científico publicado en 2006

Sequence determinants of compaction in intrinsically disordered proteins

artículo científico publicado en 2010

Sequence-Specific Polyampholyte Phase Separation in Membraneless Organelles ⬇️

artículo científico publicado en 2016

Sequential assignment of proline-rich regions in proteins: application to modular binding domain complexes

artículo científico publicado en 2000

Side-chain dynamics of the SAP SH2 domain correlate with a binding hot spot and a region with conformational plasticity

artículo científico publicado en 2002

Site-specific contributions to the pH dependence of protein stability

artículo científico publicado en 2003

Slow Dynamics in Folded and Unfolded States of an SH3 Domain ⬇️

artículo científico publicado el 21 de noviembre de 2001

Solution structure and dynamics of the outer membrane enzyme PagP by NMR.

artículo científico publicado en 2002

Solution structure of a Nedd4 WW domain-ENaC peptide complex

artículo científico publicado en 2001

Solution structure of a polypeptide dimer comprising the fourth calcium-binding site of troponin C by nuclear magnetic resonance spectroscopy

article

Stabilization of a nucleotide-binding domain of the cystic fibrosis transmembrane conductance regulator yields insight into disease-causing mutations

artículo científico publicado en 2017

Structural and Dynamic Characterization of the Phosphotyrosine Binding Region of an Src Homology 2 Domain-Phosphopeptide Complex by NMR Relaxation, Proton Exchange, and Chemical Shift Approaches

artículo científico publicado en 1995

Structural and dynamic characterization of an SH2 domain-phosphopeptide complex by NMR approaches

artículo científico publicado en 1995

Structural changes of CFTR R region upon phosphorylation: a plastic platform for intramolecular and intermolecular interactions

artículo científico

Structural characterization of folded and unfolded states of an SH3 domain in equilibrium in aqueous buffer.

artículo científico publicado en 1995

Structural characterization of proteins with an attached ATCUN motif by paramagnetic relaxation enhancement NMR spectroscopy.

artículo científico publicado en 2001

Structural comparison of the unstable drkN SH3 domain and a stable mutant

artículo científico publicado en 2005

Structural determinants for high-affinity binding in a Nedd4 WW3* domain-Comm PY motif complex

artículo científico publicado en 2006

Structural diversity in free and bound states of intrinsically disordered protein phosphatase 1 regulators

artículo científico publicado en 2010

Structural signature of the MYPT1-PP1 interaction.

artículo científico publicado en 2010

Structural studies of FF domains of the transcription factor CA150 provide insights into the organization of FF domain tandem arrays

artículo científico publicado en 2009

Structural, Functional, and Bioinformatic Studies Demonstrate the Crucial Role of an Extended Peptide Binding Site for the SH3 Domain of Yeast Abp1p

artículo científico publicado en 2009

Structure and disorder in an unfolded state under nondenaturing conditions from ensemble models consistent with a large number of experimental restraints

artículo científico publicado en 2009

Structure of a Numb PTB domain-peptide complex suggests a basis for diverse binding specificity

artículo científico publicado en 1998

Structure of a regulatory complex involving the Abl SH3 domain, the Crk SH2 domain, and a Crk-derived phosphopeptide

artículo científico publicado en 2002

Structure/function implications in a dynamic complex of the intrinsically disordered Sic1 with the Cdc4 subunit of an SCF ubiquitin ligase

artículo científico publicado en 2010

Studies on the solution conformation of human thioredoxin using heteronuclear nitrogen-15-proton nuclear magnetic resonance spectroscopy

artículo científico publicado en 1990

Synergy of cAMP and calcium signaling pathways in CFTR regulation

scientific article published on 27 February 2017

Synuclein-gamma targeting peptide inhibitor that enhances sensitivity of breast cancer cells to antimicrotubule drugs

artículo científico publicado en 2007

The 'dynamics' in the thermodynamics of binding

scientific article published on 01 December 1999

The ZIP5 ectodomain co-localizes with PrP and may acquire a PrP-like fold that assembles into a dimer

artículo científico publicado en 2013

The effect of intrachain electrostatic repulsion on conformational disorder and dynamics of the Sic1 protein

artículo científico publicado en 2014

The ubiquitin binding region of the Smurf HECT domain facilitates polyubiquitylation and binding of ubiquitylated substrates

artículo científico publicado en 2009

Theories for Sequence-Dependent Phase Behaviors of Biomolecular Condensates.

artículo científico publicado en 2018

Transient structure and dynamics in the disordered c-Myc transactivation domain affect Bin1 binding

artículo científico publicado en 2012

Tryptophan solvent exposure in folded and unfolded states of an SH3 domain by 19F and 1H NMR.

artículo científico publicado en 2006

What's in a name? Why these proteins are intrinsically disordered: Why these proteins are intrinsically disordered

artículo científico publicado en 2013

c.1058C>T variant in theSERPINC1gene is pathogenic for antithrombin deficiency

article

pE-DB: a database of structural ensembles of intrinsically disordered and of unfolded proteins

artículo científico publicado en 2014

pH titration studies of an SH2 domain-phosphopeptide complex: unusual histidine and phosphate pKa values.

artículo científico publicado en 1997

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