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Lista de obras de Nick R Lemoine

A HIF-LIMD1 negative feedback mechanism mitigates the pro-tumorigenic effects of hypoxia

scientific article published on 01 August 2018

A Simple and Efficient Approach to Construct Mutant Vaccinia Virus Vectors.

artículo científico publicado en 2016

A Virus-Infected, Reprogrammed Somatic Cell-Derived Tumor Cell (VIReST) Vaccination Regime Can Prevent Initiation and Progression of Pancreatic Cancer

scientific article published on 25 November 2019

A global insight into a cancer transcriptional space using pancreatic data: importance, findings and flaws.

artículo científico publicado en 2011

A marker-free system for highly efficient construction of vaccinia virus vectors using CRISPR Cas9.

artículo científico publicado en 2015

A multi-gene signature predicts outcome in patients with pancreatic ductal adenocarcinoma

artículo científico publicado en 2014

A novel therapeutic regimen to eradicate established solid tumors with an effective induction of tumor-specific immunity.

artículo científico publicado en 2012

A practical guide for the functional annotation of genetic variations using SNPnexus

artículo científico publicado en 2013

A vaccinia virus armed with interleukin-10 is a promising therapeutic agent for treatment of murine pancreatic cancer

artículo científico publicado en 2014

AGR2 is a novel surface antigen that promotes the dissemination of pancreatic cancer cells through regulation of cathepsins B and D

artículo científico publicado en 2011

Adenovirus-mediated sensitization to the cytotoxic drugs docetaxel and mitoxantrone is dependent on regulatory domains in the E1ACR1 gene-region

artículo científico publicado en 2012

An oncolytic adenovirus defective in pRb-binding (dl922-947) can efficiently eliminate pancreatic cancer cells and tumors in vivo in combination with 5-FU or gemcitabine.

artículo científico publicado en 2011

Anti-stromal treatment together with chemotherapy targets multiple signalling pathways in pancreatic adenocarcinoma

artículo científico publicado en 2016

Arginine deprivation and argininosuccinate synthetase expression in the treatment of cancer.

artículo científico publicado en 2010

CRISPR-Cas9 as a Powerful Tool for Efficient Creation of Oncolytic Viruses

artículo científico publicado en 2016

Combination of anti-angiogenic therapy and virotherapy: arming oncolytic viruses with anti-angiogenic genes.

artículo científico publicado en 2009

Distinct genomic alterations in prostate cancers in Chinese and Western populations suggest alternative pathways of prostate carcinogenesis.

artículo científico publicado en 2010

ER stress protein AGR2 precedes and is involved in the regulation of pancreatic cancer initiation

artículo científico publicado en 2016

Efficacy of oncolytic mutants targeting pRb and p53 pathways is synergistically enhanced when combined with cytotoxic drugs in prostate cancer cells and tumor xenografts

artículo científico publicado en 2010

Efficiently editing the vaccinia virus genome by using the CRISPR-Cas9 system.

artículo científico publicado en 2015

Identification of a Three-Biomarker Panel in Urine for Early Detection of Pancreatic Adenocarcinoma

artículo científico publicado en 2015

Immune-checkpoint blockade: the springboard for immuno-combination therapy.

artículo científico publicado en 2015

Improved potency and selectivity of an oncolytic E1ACR2 and E1B19K deleted adenoviral mutant in prostate and pancreatic cancers

artículo científico publicado en 2010

Lister strain vaccinia virus with thymidine kinase gene deletion is a tractable platform for development of a new generation of oncolytic virus.

artículo científico publicado en 2015

Lister strain vaccinia virus, a potential therapeutic vector targeting hypoxic tumours

artículo científico publicado en 2009

Lister vaccine strain of vaccinia virus armed with the endostatin-angiostatin fusion gene: an oncolytic virus superior to dl1520 (ONYX-015) for human head and neck cancer

artículo científico publicado en 2011

MHC class II molecules on pancreatic cancer cells indicate a potential for neo-antigen-based immunotherapy

scientific article published on 27 May 2022

Modification of the early gene enhancer-promoter improves the oncolytic potency of adenovirus 11.

artículo científico publicado en 2011

New role of Interleukin-10 in enhancing the antitumor efficacy of oncolytic vaccinia virus for treatment of pancreatic cancer

artículo científico publicado en 2015

Novel therapies for pancreatic cancer: setbacks and progress

scientific article published on July 2010

Nuclear translocation of FGFR1 and FGF2 in pancreatic stellate cells facilitates pancreatic cancer cell invasion

artículo científico publicado en 2014

O-miner: an integrative platform for automated analysis and mining of -omics data.

artículo científico publicado en 2012

PRSS3 promotes tumour growth and metastasis of human pancreatic cancer

artículo científico publicado en 2010

Prognostic and therapeutic impact of argininosuccinate synthetase 1 control in bladder cancer as monitored longitudinally by PET imaging

artículo científico publicado en 2013

S100P is a metastasis-associated gene that facilitates transendothelial migration of pancreatic cancer cells

artículo científico publicado en 2012

STAT1 interaction with E3-14.7K in monocytes affects the efficacy of oncolytic adenovirus

artículo científico publicado en 2013

Synergistic and Selective Cancer Cell Killing Mediated by the Oncolytic Adenoviral Mutant AdΔΔ and Dietary Phytochemicals in Prostate Cancer Models

artículo científico publicado en 2012

Systemic Delivery of Oncolytic Viruses: Hopes and Hurdles

artículo científico publicado el 31 de enero de 2012

Targeted radionuclide therapy using a Wnt-targeted replicating adenovirus encoding the Na/I symporter.

artículo científico publicado en 2009

The E1B19K-deleted oncolytic adenovirus mutant AdΔ19K sensitizes pancreatic cancer cells to drug-induced DNA-damage by down-regulating Claspin and Mre11

artículo científico publicado en 2016

The fibroblast growth factor receptor inhibitor PD173074 blocks small cell lung cancer growth in vitro and in vivo

artículo científico publicado en 2009

The oncolytic adenovirus AdΔΔ enhances selective cancer cell killing in combination with DNA-damaging drugs in pancreatic cancer models

artículo científico publicado en 2011

The pancreatic expression database: recent extensions and updates

artículo científico publicado en 2013

Update on oncolytic viral therapy - targeting angiogenesis

artículo científico

Using BioMart as a framework to manage and query pancreatic cancer data.

artículo científico publicado en 2011

Vaccinia virus, a promising new therapeutic agent for pancreatic cancer

artículo científico publicado en 2015

Vascular endothelial growth factor A promotes vaccinia virus entry into host cells via activation of the Akt pathway.

artículo científico publicado en 2012