Lista de obras - Flavio Curnis - Dominio Público Uruguay

A new chromogranin A-dependent angiogenic switch activated by thrombin

artículo científico publicado en 2012

A stapled chromogranin A-derived peptide is a potent dual ligand for integrins αvβ6 and αvβ8

artículo científico publicado en 2019

Biotinylation sites of tumor necrosis factor-alpha determined by liquid chromatography-mass spectrometry

artículo científico publicado en 2001

Boosting Interleukin-12 Antitumor Activity and Synergism with Immunotherapy by Targeted Delivery with isoDGR-Tagged Nanogold

artículo científico publicado en 2019

Ceruloplasmin functional changes in Parkinson's disease-cerebrospinal fluid

artículo científico publicado en 2015

Chromogranin A Is Preferentially Cleaved into Proangiogenic Peptides in the Bone Marrow of Multiple Myeloma Patients

artículo científico publicado en 2016

Chromogranin A binds to αvβ6-integrin and promotes wound healing in mice.

artículo científico publicado en 2012

Chromogranin A restricts drug penetration and limits the ability of NGR-TNF to enhance chemotherapeutic efficacy.

artículo científico publicado en 2011

Cleavage of chromogranin A N-terminal domain by plasmin provides a new mechanism for regulating cell adhesion

artículo científico publicado en 2002

Combined targeting of perivascular and endothelial tumor cells enhances anti-tumor efficacy of liposomal chemotherapy in neuroblastoma

artículo científico publicado en 2010

Coupling tumor necrosis factor-alpha with alphaV integrin ligands improves its antineoplastic activity

artículo científico publicado en 2004

Critical role of flanking residues in NGR-to-isoDGR transition and CD13/integrin receptor switching

artículo científico publicado en 2010

Critical role of indoleamine 2,3-dioxygenase in tumor resistance to repeated treatments with targeted IFNgamma

artículo científico publicado en 2008

Crucial role for interferon gamma in the synergism between tumor vasculature-targeted tumor necrosis factor alpha (NGR-TNF) and doxorubicin

artículo científico publicado en 2004

Enhancement of tumor necrosis factor alpha antitumor immunotherapeutic properties by targeted delivery to aminopeptidase N (CD13).

artículo científico publicado en 2000

Immunogenic and structural properties of the Asn-Gly-Arg (NGR) tumor neovasculature-homing motif

Improving chemotherapeutic drug penetration in tumors by vascular targeting and barrier alteration

article

IsoDGR-tagged albumin: a new αvβ3 selective carrier for nanodrug delivery to tumors

artículo científico publicado en 2012

Isoaspartate-dependent molecular switches for integrin–ligand recognition ⬇️

artículo científico publicado el 15 de febrero de 2011

Isoaspartate-glycine-arginine: a new tumor vasculature-targeting motif

artículo científico publicado en 2008

Myocardial production of chromogranin A in human heart: a new regulatory peptide of cardiac function

artículo científico publicado en 2007

NGR-tagged nano-gold: A new CD13-selective carrier for cytokine delivery to tumors

artículo científico publicado en 2016

Neuroblastoma-targeted nanocarriers improve drug delivery and penetration, delay tumor growth and abrogate metastatic diffusion

artículo científico publicado en 2015

Novel phage display-derived neuroblastoma-targeting peptides potentiate the effect of drug nanocarriers in preclinical settings.

artículo científico publicado en 2013

Oxidation-induced structural changes of ceruloplasmin foster NGR motif deamidation that promotes integrin binding and signaling

artículo científico publicado en 2013

Peptide-mediated targeting of cytokines to tumor vasculature: the NGR-hTNF example.

artículo científico publicado en 2013

R-CHOP preceded by blood-brain barrier permeabilization with engineered tumor necrosis factor-α in primary CNS lymphoma

scientific article published on 22 May 2019

Role of vasostatin-1 C-terminal region in fibroblast cell adhesion.

artículo científico publicado en 2010

Selective imaging of the angiogenic relevant integrins α5β1 and αvβ3.

artículo científico publicado en 2013

Spatiotemporal Regulation of Tumor Angiogenesis by Circulating Chromogranin A Cleavage and Neuropilin-1 Engagement

scientific article published on 22 February 2019

Spontaneous formation of L-isoaspartate and gain of function in fibronectin.

artículo científico publicado en 2006

Structural basis for the interaction of isoDGR with the RGD-binding site of alphavbeta3 integrin

artículo científico publicado en 2008

Structure-activity relationships of chromogranin A in cell adhesion. Identification of an adhesion site for fibroblasts and smooth muscle cells

artículo científico publicado en 2000

Structure-activity relationships of linear and cyclic peptides containing the NGR tumor-homing motif

artículo científico publicado en 2002

Synergistic antitumor activity of cisplatin, paclitaxel, and gemcitabine with tumor vasculature-targeted tumor necrosis factor-alpha

artículo científico publicado en 2006

Synergistic damage of tumor vessels with ultra low-dose endothelial-monocyte activating polypeptide-II and neovasculature-targeted tumor necrosis factor-alpha

artículo científico publicado en 2008

T Cells Redirected to a Minor Histocompatibility Antigen Instruct Intratumoral TNFα Expression and Empower Adoptive Cell Therapy for Solid Tumors.

artículo científico publicado en 2016

Targeted delivery of IFNgamma to tumor vessels uncouples antitumor from counterregulatory mechanisms

artículo científico publicado en 2005

Targeted drug delivery and penetration into solid tumors

artículo científico publicado en 2011

Targeting TNF- to Neoangiogenic Vessels Enhances Lymphocyte Infiltration in Tumors and Increases the Therapeutic Potential of Immunotherapy

artículo científico publicado en 2012

Targeting Tumor Vasculature with TNF Leads Effector T Cells to the Tumor and Enhances Therapeutic Efficacy of Immune Checkpoint Blockers in Combination with Adoptive Cell Therapy

artículo científico publicado en 2018

The neovasculature homing motif NGR: more than meets the eye.

artículo científico publicado en 2008

Tumor Vasculature Targeting Through NGR Peptide-Based Drug Delivery Systems ⬇️

artículo científico publicado el 1 de agosto de 2011

Lista de obras de Flavio Curnis

A new chromogranin A-dependent angiogenic switch activated by thrombin

A stapled chromogranin A-derived peptide is a potent dual ligand for integrins αvβ6 and αvβ8

Biotinylation sites of tumor necrosis factor-alpha determined by liquid chromatography-mass spectrometry

Boosting Interleukin-12 Antitumor Activity and Synergism with Immunotherapy by Targeted Delivery with isoDGR-Tagged Nanogold

Ceruloplasmin functional changes in Parkinson's disease-cerebrospinal fluid

Chromogranin A Is Preferentially Cleaved into Proangiogenic Peptides in the Bone Marrow of Multiple Myeloma Patients

Chromogranin A binds to αvβ6-integrin and promotes wound healing in mice.

Chromogranin A restricts drug penetration and limits the ability of NGR-TNF to enhance chemotherapeutic efficacy.

Cleavage of chromogranin A N-terminal domain by plasmin provides a new mechanism for regulating cell adhesion

Combined targeting of perivascular and endothelial tumor cells enhances anti-tumor efficacy of liposomal chemotherapy in neuroblastoma

Coupling tumor necrosis factor-alpha with alphaV integrin ligands improves its antineoplastic activity

Critical role of flanking residues in NGR-to-isoDGR transition and CD13/integrin receptor switching

Critical role of indoleamine 2,3-dioxygenase in tumor resistance to repeated treatments with targeted IFNgamma

Crucial role for interferon gamma in the synergism between tumor vasculature-targeted tumor necrosis factor alpha (NGR-TNF) and doxorubicin

Enhancement of tumor necrosis factor alpha antitumor immunotherapeutic properties by targeted delivery to aminopeptidase N (CD13).

Immunogenic and structural properties of the Asn-Gly-Arg (NGR) tumor neovasculature-homing motif

Improving chemotherapeutic drug penetration in tumors by vascular targeting and barrier alteration

IsoDGR-tagged albumin: a new αvβ3 selective carrier for nanodrug delivery to tumors

Isoaspartate-dependent molecular switches for integrin–ligand recognition ⬇️

Isoaspartate-glycine-arginine: a new tumor vasculature-targeting motif

Myocardial production of chromogranin A in human heart: a new regulatory peptide of cardiac function

NGR-tagged nano-gold: A new CD13-selective carrier for cytokine delivery to tumors

Neuroblastoma-targeted nanocarriers improve drug delivery and penetration, delay tumor growth and abrogate metastatic diffusion

Novel phage display-derived neuroblastoma-targeting peptides potentiate the effect of drug nanocarriers in preclinical settings.

Oxidation-induced structural changes of ceruloplasmin foster NGR motif deamidation that promotes integrin binding and signaling

Peptide-mediated targeting of cytokines to tumor vasculature: the NGR-hTNF example.

R-CHOP preceded by blood-brain barrier permeabilization with engineered tumor necrosis factor-α in primary CNS lymphoma

Role of vasostatin-1 C-terminal region in fibroblast cell adhesion.

Selective imaging of the angiogenic relevant integrins α5β1 and αvβ3.

Spatiotemporal Regulation of Tumor Angiogenesis by Circulating Chromogranin A Cleavage and Neuropilin-1 Engagement

Spontaneous formation of L-isoaspartate and gain of function in fibronectin.

Structural basis for the interaction of isoDGR with the RGD-binding site of alphavbeta3 integrin

Structure-activity relationships of chromogranin A in cell adhesion. Identification of an adhesion site for fibroblasts and smooth muscle cells

Structure-activity relationships of linear and cyclic peptides containing the NGR tumor-homing motif

Synergistic antitumor activity of cisplatin, paclitaxel, and gemcitabine with tumor vasculature-targeted tumor necrosis factor-alpha

Synergistic damage of tumor vessels with ultra low-dose endothelial-monocyte activating polypeptide-II and neovasculature-targeted tumor necrosis factor-alpha

T Cells Redirected to a Minor Histocompatibility Antigen Instruct Intratumoral TNFα Expression and Empower Adoptive Cell Therapy for Solid Tumors.

Targeted delivery of IFNgamma to tumor vessels uncouples antitumor from counterregulatory mechanisms

Targeted drug delivery and penetration into solid tumors

Targeting TNF- to Neoangiogenic Vessels Enhances Lymphocyte Infiltration in Tumors and Increases the Therapeutic Potential of Immunotherapy

Targeting Tumor Vasculature with TNF Leads Effector T Cells to the Tumor and Enhances Therapeutic Efficacy of Immune Checkpoint Blockers in Combination with Adoptive Cell Therapy

The neovasculature homing motif NGR: more than meets the eye.

Tumor Vasculature Targeting Through NGR Peptide-Based Drug Delivery Systems ⬇️