Lista de obras - Ana Pombo - Dominio Público Uruguay

3D chromatin regulation of Sonic hedgehog in the limb buds

artículo científico publicado en 2009

A Finer Print Than TADs: PRC1-Mediated Domains.

artículo científico publicado en 2017

A model of the large-scale organization of chromatin

artículo científico

A polymer model explains the complexity of large-scale chromatin folding

artículo científico publicado en 2013

Active RNA polymerases are localized within discrete transcription "factories' in human nuclei

artículo científico publicado en 1996

Active and poised promoter states drive folding of the extended HoxB locus in mouse embryonic stem cells.

artículo científico publicado en 2017

Adenovirus replication and transcription sites are spatially separated in the nucleus of infected cells

artículo científico publicado en 1994

Advances in imaging the interphase nucleus using thin cryosections

artículo científico publicado en 2007

An H3K9/S10 methyl-phospho switch modulates Polycomb and Pol II binding at repressed genes during differentiation

artículo científico publicado en 2014

Bridging the Resolution Gap: Imaging the Same Transcription Factories in Cryosections by Light and Electron Microscopy

article

CD8 alpha is an activation marker for a subset of peripheral CD4 T cells

artículo científico publicado en 2004

Cell cycle: Continuous chromatin changes

artículo científico publicado en 2017

Cell-type specialization is encoded by specific chromatin topologies

artículo científico publicado en 2021

Cellular genomics: which genes are transcribed, when and where?

artículo científico publicado en 2003

Challenges and guidelines toward 4D nucleome data and model standards

artículo científico publicado en 2018

Changes in chromosome organization during PHA-activation of resting human lymphocytes measured by cryo-FISH

artículo científico publicado en 2008

Chromosome organization: new facts, new models

artículo científico publicado en 2007

Code breaking: The RNAPII modification code in pluripotency ⬇️

artículo científico publicado el 1 de abril de 2012

Complex multi-enhancer contacts captured by genome architecture mapping.

artículo científico publicado en 2017

Complexity of chromatin folding is captured by the strings and binders switch model

artículo científico publicado en 2012

Correction: Transcription and Chromatin Organization of a Housekeeping Gene Cluster Containing an Integrated β-Globin Locus Control Region.

artículo científico publicado en 2008

Correlative fluorescence and electron microscopy on ultrathin cryosections: bridging the resolution gap.

artículo científico publicado en 2001

CryoFISH: fluorescence in situ hybridization on ultrathin cryosections

artículo científico publicado en 2010

Dendritic cells interact directly with naive B lymphocytes to transfer antigen and initiate class switching in a primary T-dependent response

artículo científico publicado en 1998

Desmin immunolocalisation in autosomal dominant Emery-Dreifuss muscular dystrophy

artículo científico publicado en 2007

Distribution of different phosphorylated forms of RNA polymerase II in relation to Cajal and PML bodies in human cells: an ultrastructural study

artículo científico publicado en 2005

Erratum: Three-dimensional genome architecture: players and mechanisms

scholarly article published in Nature Reviews Molecular Cell Biology

Eukaryotic gene regulation in three dimensions and its impact on genome evolution

artículo científico publicado en 2008

Examining Topological Domain Influence on Enhancer Function

artículo científico publicado en 2016

FANTOM5 CAGE profiles of human and mouse samples

artículo científico

Fixation-induced redistribution of hyperphosphorylated RNA polymerase II in the nucleus of human cells

artículo científico publicado en 2004

Flipping between Polycomb repressed and active transcriptional states introduces noise in gene expression

artículo científico publicado en 2017

Flipping between Polycomb repressed and active transcriptional states introduces noise in gene expression

article

Formation of new chromatin domains determines pathogenicity of genomic duplications

artículo científico publicado en 2016

From linear genome sequence to three-dimensional organization of the cell nucleus

artículo científico publicado en 2003

Functional analysis of Vif protein shows less restriction of human immunodeficiency virus type 2 by APOBEC3G.

artículo científico publicado en 2005

Functional organisation of the genome during interphase

artículo científico publicado en 2007

Gene activation by metazoan enhancers: Diverse mechanisms stimulate distinct steps of transcription

artículo científico publicado en 2016

Gene positioning

artículo científico publicado en 2010

Genome function and nuclear architecture: from gene expression to nanoscience

artículo científico publicado en 2003

Genomics meets nanoscience: probing genes and the cell nucleus at 10-9 meters

artículo científico publicado en 2002

Hierarchical folding and reorganization of chromosomes are linked to transcriptional changes in cellular differentiation.

artículo científico publicado en 2015

Interaction of proteins with promoter elements of the human U2 snRNA genes in vivo

artículo científico publicado en 2003

Interactions of adenovirus with the nucleus of the host cell

scholarly article by Ana Pombo published in December 1995

Intermingling of chromosome territories in interphase suggests role in translocations and transcription-dependent associations

artículo científico publicado en 2006

Jarid2 is a PRC2 component in embryonic stem cells required for multi-lineage differentiation and recruitment of PRC1 and RNA Polymerase II to developmental regulators.

artículo científico publicado en 2010

Keep Them Close: PRC2 Poises Enhancer-Promoter Interactions at Anterior Neuronal Genes

artículo científico publicado en 2017

LifeTime and improving European healthcare through cell-based interceptive medicine

artículo científico publicado en 2020

Localization of a putative transcriptional regulator (ATRX) at pericentromeric heterochromatin and the short arms of acrocentric chromosomes

artículo científico publicado en 1999

Maternal immune activation results in complex microglial transcriptome signature in the adult offspring that is reversed by minocycline treatment.

artículo científico publicado en 2017

Mean Expression of the X-Chromosome is Associated with Neuronal Density

artículo científico publicado en 2012

Measurement of replication structures at the nanometer scale using super-resolution light microscopy

artículo científico publicado en 2009

Measuring the size of biological nanostructures with spatially modulated illumination microscopy

artículo científico publicado en 2004

Mechanical regulation of transcription controls Polycomb-mediated gene silencing during lineage commitment

artículo científico publicado en 2016

Mechanisms regulating S phase progression in mammalian cells

artículo científico publicado en 2009

Methods for mapping 3D chromosome architecture

artículo científico publicado en 2019

Methylation of RNA polymerase II non-consensus Lysine residues marks early transcription in mammalian cells

artículo científico publicado en 2015

Models of chromosome structure

artículo científico publicado en 2014

Modifications of RNA polymerase II are pivotal in regulating gene expression states

artículo científico publicado en 2009

Nuclear Architecture in Stem Cells

scientific article published on 01 January 2010

Nuclear cell biology ⬇️

artículo científico publicado el 15 de marzo de 2011

Nucleus and gene expression: the structure and function conundrum

article

On the structure of replication and transcription factories

artículo científico publicado en 1995

Phenotypic analysis of peripheral CD4+ CD8+ T cells in the rat

article

Physical mechanisms behind the large scale features of chromatin organization

artículo científico publicado en 2014

Poised transcription factories prime silent uPA gene prior to activation.

artículo científico publicado en 2010

Polycomb associates genome-wide with a specific RNA polymerase II variant, and regulates metabolic genes in ESCs

artículo científico publicado en 2012

Polycomb targets seek closest neighbours

artículo científico publicado en 2011

Polymer models of chromatin organization

artículo científico publicado en 2013

Polymer models of the organization of chromosomes in the nucleus of cells

Polymer physics predicts the effects of structural variants on chromatin architecture

artículo científico publicado en 2018

Polymer physics, scaling and heterogeneity in the spatial organisation of chromosomes in the cell nucleus

Proteomic analysis of mitotic RNA polymerase II reveals novel interactors and association with proteins dysfunctional in disease

artículo científico publicado en 2011

Publisher Correction: LifeTime and improving European healthcare through cell-based interceptive medicine

artículo científico publicado en 2021

R-Loops Enhance Polycomb Repression at a Subset of Developmental Regulator Genes

article

RNA polymerase II primes Polycomb-repressed developmental genes throughout terminal neuronal differentiation.

artículo científico publicado en 2017

Regional and temporal specialization in the nucleus: a transcriptionally-active nuclear domain rich in PTF, Oct1 and PIKA antigens associates with specific chromosomes early in the cell cycle

artículo científico publicado en 1998

Regional specialization in human nuclei: visualization of discrete sites of transcription by RNA polymerase III.

artículo científico publicado en 1999

Replicon clusters are stable units of chromosome structure: evidence that nuclear organization contributes to the efficient activation and propagation of S phase in human cells

artículo científico publicado en 1998

Ring1-mediated ubiquitination of H2A restrains poised RNA polymerase II at bivalent genes in mouse ES cells

article

Ring1B and Suv39h1 delineate distinct chromatin states at bivalent genes during early mouse lineage commitment

artículo científico publicado en 2010

Short RNAs are transcribed from repressed polycomb target genes and interact with polycomb repressive complex-2.

artículo científico publicado en 2010

Specialized transcription factories within mammalian nuclei.

artículo científico publicado en 2000

Splicing speckles are not reservoirs of RNA polymerase II, but contain an inactive form, phosphorylated on serine2 residues of the C-terminal domain

artículo científico publicado en 2006

Stem Cell Epigenetics: Looking Forward

artículo científico publicado en 2014

The localization of sites containing nascent RNA and splicing factors.

artículo científico publicado en 1996

The molecular basis for stability of heterochromatin-mediated silencing in mammals

artículo científico publicado en 2009

The topology of transcription by immobilized polymerases.

artículo científico

Three-dimensional genome architecture: players and mechanisms

artículo científico publicado en 2015

Transcribed enhancers lead waves of coordinated transcription in transitioning mammalian cells

artículo científico publicado en 2015

Transcription and chromatin organization of a housekeeping gene cluster containing an integrated beta-globin locus control region

artículo científico publicado en 2008

Transcription factories: quantitative studies of nanostructures in the mammalian nucleus

artículo científico publicado en 2003

Variant histone H3.3 marks promoters of transcriptionally active genes during mammalian cell division

artículo científico publicado en 2005

Lista de obras de Ana Pombo

3D chromatin regulation of Sonic hedgehog in the limb buds

A Finer Print Than TADs: PRC1-Mediated Domains.

A model of the large-scale organization of chromatin

A polymer model explains the complexity of large-scale chromatin folding

Active RNA polymerases are localized within discrete transcription "factories' in human nuclei

Active and poised promoter states drive folding of the extended HoxB locus in mouse embryonic stem cells.

Adenovirus replication and transcription sites are spatially separated in the nucleus of infected cells

Advances in imaging the interphase nucleus using thin cryosections

An H3K9/S10 methyl-phospho switch modulates Polycomb and Pol II binding at repressed genes during differentiation

Bridging the Resolution Gap: Imaging the Same Transcription Factories in Cryosections by Light and Electron Microscopy

CD8 alpha is an activation marker for a subset of peripheral CD4 T cells

Cell cycle: Continuous chromatin changes

Cell-type specialization is encoded by specific chromatin topologies

Cellular genomics: which genes are transcribed, when and where?

Challenges and guidelines toward 4D nucleome data and model standards

Changes in chromosome organization during PHA-activation of resting human lymphocytes measured by cryo-FISH

Chromosome organization: new facts, new models

Code breaking: The RNAPII modification code in pluripotency ⬇️

Complex multi-enhancer contacts captured by genome architecture mapping.

Complexity of chromatin folding is captured by the strings and binders switch model

Correction: Transcription and Chromatin Organization of a Housekeeping Gene Cluster Containing an Integrated β-Globin Locus Control Region.

Correlative fluorescence and electron microscopy on ultrathin cryosections: bridging the resolution gap.

CryoFISH: fluorescence in situ hybridization on ultrathin cryosections

Dendritic cells interact directly with naive B lymphocytes to transfer antigen and initiate class switching in a primary T-dependent response

Desmin immunolocalisation in autosomal dominant Emery-Dreifuss muscular dystrophy

Distribution of different phosphorylated forms of RNA polymerase II in relation to Cajal and PML bodies in human cells: an ultrastructural study

Erratum: Three-dimensional genome architecture: players and mechanisms

Eukaryotic gene regulation in three dimensions and its impact on genome evolution

Examining Topological Domain Influence on Enhancer Function

FANTOM5 CAGE profiles of human and mouse samples

Fixation-induced redistribution of hyperphosphorylated RNA polymerase II in the nucleus of human cells

Flipping between Polycomb repressed and active transcriptional states introduces noise in gene expression

Flipping between Polycomb repressed and active transcriptional states introduces noise in gene expression

Formation of new chromatin domains determines pathogenicity of genomic duplications

From linear genome sequence to three-dimensional organization of the cell nucleus

Functional analysis of Vif protein shows less restriction of human immunodeficiency virus type 2 by APOBEC3G.

Functional organisation of the genome during interphase

Gene activation by metazoan enhancers: Diverse mechanisms stimulate distinct steps of transcription

Gene positioning

Genome function and nuclear architecture: from gene expression to nanoscience

Genomics meets nanoscience: probing genes and the cell nucleus at 10-9 meters

Hierarchical folding and reorganization of chromosomes are linked to transcriptional changes in cellular differentiation.

Interaction of proteins with promoter elements of the human U2 snRNA genes in vivo

Interactions of adenovirus with the nucleus of the host cell

Intermingling of chromosome territories in interphase suggests role in translocations and transcription-dependent associations

Jarid2 is a PRC2 component in embryonic stem cells required for multi-lineage differentiation and recruitment of PRC1 and RNA Polymerase II to developmental regulators.

Keep Them Close: PRC2 Poises Enhancer-Promoter Interactions at Anterior Neuronal Genes

LifeTime and improving European healthcare through cell-based interceptive medicine

Localization of a putative transcriptional regulator (ATRX) at pericentromeric heterochromatin and the short arms of acrocentric chromosomes

Maternal immune activation results in complex microglial transcriptome signature in the adult offspring that is reversed by minocycline treatment.

Mean Expression of the X-Chromosome is Associated with Neuronal Density

Measurement of replication structures at the nanometer scale using super-resolution light microscopy

Measuring the size of biological nanostructures with spatially modulated illumination microscopy

Mechanical regulation of transcription controls Polycomb-mediated gene silencing during lineage commitment

Mechanisms regulating S phase progression in mammalian cells

Methods for mapping 3D chromosome architecture

Methylation of RNA polymerase II non-consensus Lysine residues marks early transcription in mammalian cells

Models of chromosome structure

Modifications of RNA polymerase II are pivotal in regulating gene expression states

Nuclear Architecture in Stem Cells

Nuclear cell biology ⬇️

Nucleus and gene expression: the structure and function conundrum

On the structure of replication and transcription factories

Phenotypic analysis of peripheral CD4+ CD8+ T cells in the rat

Physical mechanisms behind the large scale features of chromatin organization

Poised transcription factories prime silent uPA gene prior to activation.

Polycomb associates genome-wide with a specific RNA polymerase II variant, and regulates metabolic genes in ESCs

Polycomb targets seek closest neighbours

Polymer models of chromatin organization

Polymer models of the organization of chromosomes in the nucleus of cells

Polymer physics predicts the effects of structural variants on chromatin architecture

Polymer physics, scaling and heterogeneity in the spatial organisation of chromosomes in the cell nucleus

Proteomic analysis of mitotic RNA polymerase II reveals novel interactors and association with proteins dysfunctional in disease

Publisher Correction: LifeTime and improving European healthcare through cell-based interceptive medicine

R-Loops Enhance Polycomb Repression at a Subset of Developmental Regulator Genes

RNA polymerase II primes Polycomb-repressed developmental genes throughout terminal neuronal differentiation.

Regional and temporal specialization in the nucleus: a transcriptionally-active nuclear domain rich in PTF, Oct1 and PIKA antigens associates with specific chromosomes early in the cell cycle

Regional specialization in human nuclei: visualization of discrete sites of transcription by RNA polymerase III.

Replicon clusters are stable units of chromosome structure: evidence that nuclear organization contributes to the efficient activation and propagation of S phase in human cells