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Lista de obras de Andrew P Halestrap

A novel postsynaptic density protein: the monocarboxylate transporter MCT2 is co-localized with delta-glutamate receptors in postsynaptic densities of parallel fiber-Purkinje cell synapses

artículo científico publicado en 2001

A pore way to die

artículo científico publicado en 2005

A pore way to die: the role of mitochondria in reperfusion injury and cardioprotection

artículo científico publicado en 2010

A re-evaluation of the role of mitochondrial pyruvate transport in the hormonal control of rat liver mitochondrial pyruvate metabolism

artículo científico publicado en 1984

Abundance and subcellular distribution of MCT1 and MCT4 in heart and fast-twitch skeletal muscles

artículo científico publicado en 2000

Aluminum citrate uptake by immortalized brain endothelial cells: implications for its blood-brain barrier transport.

artículo científico publicado en 2002

Apoptosis and the laws of thermodynamics

artículo científico publicado en 2000

Butyrate can act as a stimulator of growth or inducer of apoptosis in human colonic epithelial cell lines depending on the presence of alternative energy sources

artículo científico publicado en 1997

CD147 is tightly associated with lactate transporters MCT1 and MCT4 and facilitates their cell surface expression

artículo científico publicado en 2000

Calcium, mitochondria and reperfusion injury: a pore way to die.

artículo científico publicado en 2006

Calcium-dependent opening of a non-specific pore in the mitochondrial inner membrane is inhibited at pH values below 7. Implications for the protective effect of low pH against chemical and hypoxic cell damage ⬇️

artículo científico publicado el 15 de septiembre de 1991

Cellular and subcellular distribution of monocarboxylate transporters in cultured brain cells and in the adult brain.

artículo científico publicado en 2005

Cellular and subcellular expression of monocarboxylate transporters in the pigment epithelium and retina of the rat

artículo científico publicado en 1999

Chaotropic agents and increased matrix volume enhance binding of mitochondrial cyclophilin to the inner mitochondrial membrane and sensitize the mitochondrial permeability transition to [Ca2+]

scientific article published on 01 June 1996

Characterisation of human monocarboxylate transporter 4 substantiates its role in lactic acid efflux from skeletal muscle

artículo científico publicado en 2000

Characterization of the enhanced transport of L- and D-lactate into human red blood cells infected with Plasmodium falciparum suggests the presence of a novel saturable lactate proton cotransporter

artículo científico publicado en 1995

Characterization of the high-affinity monocarboxylate transporter MCT2 in Xenopus laevis oocytes

artículo científico publicado en 1999

Characterization of the inhibition by stilbene disulphonates and phloretin of lactate and pyruvate transport into rat and guinea-pig cardiac myocytes suggests the presence of two kinetically distinct carriers in heart cells

artículo científico publicado en 1993

Chloride-independent transport of pyruvate and lactate across the erythrocyte membrane [proceedings]

artículo científico publicado en 1978

Chronic electrical stimulation increases MCT1 and lactate uptake in red and white skeletal muscle

scientific article published on 01 August 1997

Clinically-relevant consecutive treatment with isoproterenol and adenosine protects the failing heart against ischaemia and reperfusion

artículo científico publicado en 2014

Cloning and sequencing of four new mammalian monocarboxylate transporter (MCT) homologues confirms the existence of a transporter family with an ancient past ⬇️

artículo científico publicado el 15 de enero de 1998

Cloning and sequencing of the monocarboxylate transporter from mouse Ehrlich Lettré tumour cell confirms its identity as MCT1 and demonstrates that glycosylation is not required for MCT1 function

artículo científico publicado en 1996

Cloning of the monocarboxylate transporter isoform MCT2 from rat testis provides evidence that expression in tissues is species-specific and may involve post-transcriptional regulation

scientific journal article

Computer simulation of the effects of alpha-cyano-4-hydroxycinnamate on gluconeogenesis from L-lactate in rat liver cells

artículo científico publicado en 1981

Cross-reinnervation changes the expression patterns of the monocarboxylate transporters 1 and 4: An experimental study in slow and fast rat skeletal muscle

artículo científico publicado en 2006

Cyclosporin A and its nonimmunosuppressive analogue N-Me-Val-4-cyclosporin A mitigate glucose/oxygen deprivation-induced damage to rat cultured hippocampal neurons

artículo científico publicado en 1999

Cyclosporin A binding to mitochondrial cyclophilin inhibits the permeability transition pore and protects hearts from ischaemia/reperfusion injury

artículo científico publicado en 1997

Cyclosporin A, but not FK 506, protects mitochondria and neurons against hypoglycemic damage and implicates the mitochondrial permeability transition in cell death.

artículo científico publicado en 1998

Cytochrome c release from isolated rat liver mitochondria can occur independently of outer-membrane rupture: possible role of contact sites

artículo científico publicado en 2000

Derivatives of cinnamic acid interact with the nucleotide binding site of mitochondrial aldehyde dehydrogenase. Effects on the dehydrogenase reaction and stimulation of esterase activity by nucleotides

artículo científico publicado en 1993

Determination of the rate of K(+) movement through potassium channels in isolated rat heart and liver mitochondria

artículo científico publicado en 2008

Differences in the activation of the mitochondrial permeability transition among brain regions in the rat correlate with selective vulnerability

artículo científico publicado en 1999

Differences in the profile of protection afforded by TRO40303 and mild hypothermia in models of cardiac ischemia/reperfusion injury.

artículo científico publicado en 2015

Does the mitochondrial permeability transition have a role in preconditioning?

artículo científico publicado en 2004

Effect of high-intensity exercise training on lactate/H+ transport capacity in human skeletal muscle

artículo científico publicado en 1999

Effects of glucagon and Ca2+ on the metabolism of phosphatidylinositol 4-phosphate and phosphatidylinositol 4,5-bisphosphate in isolated rat hepatocytes and plasma membranes

artículo científico publicado en 1987

Effects of tyrosine kinase inhibitors on protein kinase-independent systems

artículo científico publicado en 1993

Elucidating the molecular mechanism of the permeability transition pore and its role in reperfusion injury of the heart

artículo científico

Energy metabolism during apoptosis. Bcl-2 promotes survival in hematopoietic cells induced to apoptose by growth factor withdrawal by stabilizing a form of metabolic arrest

artículo científico publicado en 1997

Enhanced expression of three monocarboxylate transporter isoforms in the brain of obese mice.

artículo científico publicado en 2007

Evidence that the flux control coefficient of the respiratory chain is high during gluconeogenesis from lactate in hepatocytes from starved rats. Implications for the hormonal control of gluconeogenesis and action of hypoglycaemic agents

artículo científico publicado en 1987

Expression and distribution of lactate/monocarboxylate transporter isoforms in pancreatic islets and the exocrine pancreas

artículo científico publicado en 2001

Expression of the lactate transporter MCT1 in macrophages

artículo científico publicado en 2000

Extent of mitochondrial hexokinase II dissociation during ischemia correlates with mitochondrial cytochrome c release, reactive oxygen species production, and infarct size on reperfusion

artículo científico publicado en 2012

Fluorescence resonance energy transfer studies on the interaction between the lactate transporter MCT1 and CD147 provide information on the topology and stoichiometry of the complex in situ

scientific journal article

Further evidence that cyclosporin A protects mitochondria from calcium overload by inhibiting a matrix peptidyl-prolyl cis-trans isomerase. Implications for the immunosuppressive and toxic effects of cyclosporin

artículo científico publicado en 1991

Glucagon treatment of rats activates the respiratory chain of liver mitochondria at more than one site

artículo científico publicado en 1987

Glucagon treatment of rats inhibits the accumulation of lysophospholipids by liver mitochondria during preparation and subsequent incubation

scientific article published on 01 November 1984

Glutamate loading protects freshly isolated and perfused adult cardiomyocytes against intracellular ROS generation

artículo científico publicado en 2003

Hearts from mice fed a non-obesogenic high-fat diet exhibit changes in their oxidative state, calcium and mitochondria in parallel with increased susceptibility to reperfusion injury

artículo científico publicado en 2014

Hexokinase II and reperfusion injury: TAT-HK2 peptide impairs vascular function in Langendorff-perfused rat hearts.

artículo científico publicado en 2013

Hexokinase II dissociation alone cannot account for changes in heart mitochondrial function, morphology and sensitivity to permeability transition pore opening following ischemia

artículo científico publicado en 2020

Highly differential expression of the monocarboxylate transporters MCT2 and MCT4 in the developing rat brain

scientific journal article

Hormonal regulation of adipose-tissue acetyl-Coenzyme A carboxylase by changes in the polymeric state of the enzyme. The role of long-chain fatty acyl-Coenzyme A thioesters and citrate

artículo científico publicado en 1974

Identification and characterisation of a new class of highly specific and potent inhibitors of the mitochondrial pyruvate carrier.

artículo científico publicado en 2004

Identification and partial purification of the erythrocyte L-lactate transporter

artículo científico publicado en 1992

Identification of key binding site residues of MCT1 for AR-C155858 reveals the molecular basis of its isoform selectivity

artículo científico publicado en 2015

Identification of key binding site residues of MCT1 for AR-C155858 reveals the molecular basis of its isoform selectivity

artículo científico publicado en 2015

Identification of monocarboxylate transporter 8 as a specific thyroid hormone transporter

scientific journal article

Identification of the mitochondrial pyruvate carrier in Saccharomyces cerevisiae.

artículo científico publicado en 2003

Identification of the protein responsible for pyruvate transport into rat liver and heart mitochondria by specific labelling with [3H]N-phenylmaleimide

artículo científico publicado en 1981

In vivo pH in metabolic-defective Ras-transformed fibroblast tumors: key role of the monocarboxylate transporter, MCT4, for inducing an alkaline intracellular pH.

artículo científico publicado en 2011

Increases in muscle MCT are associated with reductions in muscle lactate after a single exercise session in humans

artículo científico publicado en 2002

Inhibition and labelling of the erythrocyte lactate transporter by stilbene disulphonates

artículo científico publicado en 1990

Inhibition of Ca2(+)-induced large-amplitude swelling of liver and heart mitochondria by cyclosporin is probably caused by the inhibitor binding to mitochondrial-matrix peptidyl-prolyl cis-trans isomerase and preventing it interacting with the adeni

artículo científico publicado en 1990

Inhibition of L-lactate transport and band 3-mediated anion transport in erythrocytes by the novel stilbenedisulphonate N,N,N',N'-tetrabenzyl-4,4'-diaminostilbene-2,2'-disulpho nat e (TBenzDS)

artículo científico publicado en 1991

Inhibition of human immunodeficiency virus type 1 replication in human cells by Debio-025, a novel cyclophilin binding agent

artículo científico publicado en 2008

Inhibition of mitochondrial permeability transition pore opening by ischemic preconditioning is probably mediated by reduction of oxidative stress rather than mitochondrial protein phosphorylation.

artículo científico publicado en 2008

Inhibition of mitochondrial pyruvate transport by phenylpyruvate and alpha-ketoisocaproate

artículo científico publicado en 1974

Inhibition of mitochondrial-matrix inorganic pyrophosphatase by physiological [Ca2+], and its role in the hormonal regulation of mitochondrial matrix volume

artículo científico publicado en 1989

Inorganic pyrophosphate is located primarily in the mitochondria of the hepatocyte and increases in parallel with the decrease in light-scattering induced by gluconeogenic hormones, butyrate and ionophore A23187.

artículo científico publicado en 1988

Insulin and the regulation of adipose tissue acetyl-coenzyme A carboxylase

artículo científico publicado en 1973

Interaction of the erythrocyte lactate transporter (monocarboxylate transporter 1) with an integral 70-kDa membrane glycoprotein of the immunoglobulin superfamily

artículo científico publicado en 1997

Intracellular ATP-sensitive K+ channels in mouse pancreatic beta cells: against a role in organelle cation homeostasis

artículo científico publicado en 2006

Intramitochondrial regulation of fatty acid beta-oxidation occurs between flavoprotein and ubiquinone. A role for changes in the matrix volume

artículo científico publicado en 1986

Ischaemic preconditioning inhibits opening of mitochondrial permeability transition pores in the reperfused rat heart

artículo científico publicado en 2003

Isoform-specific regulation of the lactate transporters MCT1 and MCT4 by contractile activity

artículo científico publicado en 2000

Kinetics of the sarcolemmal lactate carrier in single heart cells using BCECF to measure pHi.

artículo científico publicado en 1994

Lactate Transport in Heart in Relation to Myocardial Ischemia ⬇️

artículo científico publicado el 4 de agosto de 1997

Lactate transport in skeletal muscle - role and regulation of the monocarboxylate transporter.

artículo científico publicado en 1999

Lactate-proton co-transport and its contribution to interstitial acidification during hypoxia in isolated rat spinal roots

scientific article published on 01 April 1993

Lactic acid efflux from white skeletal muscle is catalyzed by the monocarboxylate transporter isoform MCT3.

artículo científico publicado en 1998

Liver mitochondrial pyrophosphate concentration is increased by Ca2+ and regulates the intramitochondrial volume and adenine nucleotide content

artículo científico publicado en 1987

Maintenance of complex I and its supercomplexes by NDUF-11 is essential for mitochondrial structure, function and health

artículo científico publicado en 2021

Matrix volume measurements challenge the existence of diazoxide/glibencamide-sensitive KATP channels in rat mitochondria

artículo científico publicado en 2003

Measurement of the intramitochondrial volume in hepatocytes without cell disruption and its elevation by hormones and valinomycin

artículo científico publicado en 1983

Mechanism of action of the antifibrogenic compound gliotoxin in rat liver cells.

artículo científico publicado en 2004

Mechanism of antineoplastic activity of lonidamine

artículo científico publicado en 2016

Mechanisms involved in hormone signal transduction across the mitochondrial membrane

artículo científico publicado en 1985

Mitochondria and cell death.

artículo científico publicado en 2000

Mitochondria and cell death: a pore way to die?

artículo científico publicado en 2000

Mitochondria and preconditioning: a connexin connection?

artículo científico publicado en 2006

Mitochondria: a target for myocardial protection.

artículo científico publicado en 2001

Mitochondrial 'flashes': a radical concept repHined.

artículo científico publicado en 2012

Mitochondrial calcium handling and oxidative stress

artículo científico publicado en 1993

Mitochondrial calcium in health and disease

artículo científico publicado en 2009

Mitochondrial non-specific pores remain closed during cardiac ischaemia, but open upon reperfusion

artículo científico publicado en 1995

Mitochondrial permeability: dual role for the ADP/ATP translocator?

artículo científico publicado en 2004

Mitochondrial pyruvate transport and its hormonal regulation

artículo científico publicado en 1980

Monocarboxylic acid transport

artículo científico

N-terminal protein sequence analysis of the rabbit erythrocyte lactate transporter suggests identity with the cloned monocarboxylate transport protein MCT1.

artículo científico publicado en 1994

Overexpression of monocarboxylate transporter-1 (SLC16A1) in mouse pancreatic β-cells leads to relative hyperinsulinism during exercise

scientific journal article

Oxidative stress, thiol reagents, and membrane potential modulate the mitochondrial permeability transition by affecting nucleotide binding to the adenine nucleotide translocase

artículo científico

Partial inhibition by cyclosporin A of the swelling of liver mitochondria in vivo and in vitro induced by sub-micromolar [Ca2+], but not by butyrate. Evidence for two distinct swelling mechanisms

artículo científico publicado en 1990

Phosphorylation of branched-chain 2-oxo acid dehydrogenase within intact mitochondria [proceedings]

artículo científico publicado en 1980

Physical exercise-induced hypoglycemia caused by failed silencing of monocarboxylate transporter 1 in pancreatic beta cells

artículo científico publicado en 2007

Propofol is cardioprotective in a clinically relevant model of normothermic blood cardioplegic arrest and cardiopulmonary bypass

artículo científico publicado en 2005

Protection by Cyclosporin A of ischemia/reperfusion-induced damage in isolated rat hearts.

artículo científico publicado en 1993

Protection of hearts from reperfusion injury by propofol is associated with inhibition of the mitochondrial permeability transition

artículo científico publicado en 2000

Purification and N-terminal sequencing of peptidyl-prolyl cis-trans-isomerase from rat liver mitochondrial matrix reveals the existence of a distinct mitochondrial cyclophilin ⬇️

artículo científico publicado el 1 de junio de 1992

Purification of aldehyde dehydrogenase from rat liver mitochondria by alpha-cyanocinnamate affinity chromatography

artículo científico publicado en 1989

Pyrophosphate metabolism in the perfused heart and isolated heart mitochondria and its role in regulation of mitochondrial function by calcium

artículo científico publicado en 1993

Pyruvate and ketone-body transport across the mitochondrial membrane. Exchange properties, pH-dependence and mechanism of the carrier ⬇️

artículo científico publicado el 15 de junio de 1978

Pyruvate imbalance mediates metabolic reprogramming and mimics lifespan extension by dietary restriction in Caenorhabditis elegans

artículo científico publicado en 2010

Quantification of active mitochondrial permeability transition pores using GNX-4975 inhibitor titrations provides insights into molecular identity

artículo científico publicado en 2016

Rat liver mitochondria prepared in mannitol media demonstrate increased mitochondrial volumes compared with mitochondria prepared in sucrose media. Relationship to the effect of glucagon on mitochondrial function

artículo científico publicado en 1984

Recent progress in elucidating the molecular mechanism of the mitochondrial permeability transition pore.

scientific article published on 25 March 2008

Reconstitution of the L-lactate carrier from rat and rabbit erythrocyte plasma membranes

artículo científico publicado en 1988

Recruitment of mitochondrial cyclophilin to the mitochondrial inner membrane under conditions of oxidative stress that enhance the opening of a calcium-sensitive non-specific channel

artículo científico publicado en 1994

Regulation of mitochondrial metabolism through changes in matrix volume

scientific article published on 01 May 1994

Regulation of pyruvate metabolism in mammalian tissues

artículo científico publicado en 1979

Regulation of the mitochondrial matrix volume in vivo and in vitro. The role of calcium

artículo científico publicado en 1986

Reversal of permeability transition during recovery of hearts from ischemia and its enhancement by pyruvate

artículo científico publicado en 1999

Reversible and irreversible inhibition, by stilbenedisulphonates, of lactate transport into rat erythrocytes. Identification of some new high-affinity inhibitors

artículo científico publicado en 1991

Role of critical thiol groups on the matrix surface of the adenine nucleotide translocase in the mechanism of the mitochondrial permeability transition pore

artículo científico publicado en 2002

Role of the lactate transporter (MCT1) in skeletal muscles

artículo científico publicado en 1996

Sanglifehrin A acts as a potent inhibitor of the mitochondrial permeability transition and reperfusion injury of the heart by binding to cyclophilin-D at a different site from cyclosporin A.

artículo científico publicado en 2002

Specific inhibition of pyruvate transport in rat liver mitochondria and human erythrocytes by alpha-cyano-4-hydroxycinnamate

scientific journal article

Stimulation of pyruvate transport in metabolizing mitochondria through changes in the transmembrane pH gradient induced by glucagon treatment of rats ⬇️

artículo científico publicado el 15 de junio de 1978

Stimulation of the respiratory chain of rat liver mitochondria between cytochrome c1 and cytochrome c by glucagon treatment of rats ⬇️

artículo científico publicado el 15 de junio de 1978

Studies of the membrane topology of the rat erythrocyte H+/lactate cotransporter (MCT1).

artículo científico publicado en 1996

Studies on the DIDS-binding site of monocarboxylate transporter 1 suggest a homology model of the open conformation and a plausible translocation cycle

scientific journal article

Substrate and inhibitor specificities of the monocarboxylate transporters of single rat heart cells

artículo científico publicado en 1996

Substrate and inhibitor specificity of monocarboxylate transport into heart cells and erythrocytes. Further evidence for the existence of two distinct carriers

artículo científico publicado en 1990

Switching back to normal diet following high-fat diet feeding reduces cardiac vulnerability to ischaemia and reperfusion injury.

artículo científico publicado en 2014

Temperature preconditioning of isolated rat hearts--a potent cardioprotective mechanism involving a reduction in oxidative stress and inhibition of the mitochondrial permeability transition pore

artículo científico publicado en 2007

The 'mitoflash' probe cpYFP does not respond to superoxide

artículo científico publicado en 2014

The C Ring of the F1Fo ATP Synthase Forms the Mitochondrial Permeability Transition Pore: A Critical Appraisal

artículo científico publicado en 2014

The Mitochondrial Pyruvate Carrier: Has It Been Unearthed at Last? ⬇️

artículo científico publicado el 8 de agosto de 2012

The SLC16 gene family – Structure, role and regulation in health and disease ⬇️

artículo científico publicado el 1 de abril de 2013

The SLC16 gene family?from monocarboxylate transporters (MCTs) to aromatic amino acid transporters and beyond ⬇️

artículo científico publicado el 9 de mayo de 2003

The adenine nucleotide translocase: a central component of the mitochondrial permeability transition pore and key player in cell death.

artículo científico publicado en 2003

The anti-tumour agent lonidamine is a potent inhibitor of the mitochondrial pyruvate carrier and plasma membrane monocarboxylate transporters.

artículo científico publicado en 2016

The concentration of the mitochondrial pyruvate carrier in rat liver and heart mitochondria determined with alpha-cyano-beta-(1-phenylindol-3-yl)acrylate

artículo científico publicado en 1984

The effects of glucagon, phenylephrine and insulin on the phosphorylation of cytoplasmic, mitochondrial and membrane-bound proteins of intact liver cells from starved rats

artículo científico publicado en 1982

The effects of ischaemic preconditioning, diazoxide and 5-hydroxydecanoate on rat heart mitochondrial volume and respiration

artículo científico publicado en 2002

The enemy of science is within

artículo científico publicado en 1996

The intramitochondrial volume measured using sucrose as an extramitochondrial marker overestimates the true matrix volume determined with mannitol

artículo científico publicado en 1983

The involvement of mitochondrial pyruvate transport in the pathways of gluconeogenesis from serine and alanine in isolated rat and mouse liver cells

scientific article published on 01 April 1975

The kinetics of transport of lactate and pyruvate into isolated cardiac myocytes from guinea pig. Kinetic evidence for the presence of a carrier distinct from that in erythrocytes and hepatocytes

artículo científico publicado en 1989

The kinetics of transport of lactate and pyruvate into rat hepatocytes. Evidence for the presence of a specific carrier similar to that in erythrocytes

artículo científico publicado en 1988

The kinetics, substrate and inhibitor specificity of the lactate transporter of Ehrlich-Lettre tumour cells studied with the intracellular pH indicator BCECF.

artículo científico publicado en 1994

The kinetics, substrate, and inhibitor specificity of the monocarboxylate (lactate) transporter of rat liver cells determined using the fluorescent intracellular pH indicator, 2',7'-bis(carboxyethyl)-5(6)-carboxyfluorescein

artículo científico publicado en 1996

The mechanism of action of FK 506.

artículo científico publicado en 1990

The mechanism of the hormonal activation of respiration in isolated hepatocytes and its importance in the regulation of gluconeogenesis

artículo científico publicado en 1986

The mechanism of the inhibition of the mitochondrial pyruvate transportater by alpha-cyanocinnamate derivatives ⬇️

artículo científico publicado el 15 de abril de 1976

The mechanism of the stimulation of pyruvate transport into rat liver mitochondria by glucagon

artículo científico publicado el 1 de enero de 1977

The mechanisms by which mild respiratory chain inhibitors inhibit hepatic gluconeogenesis

artículo científico publicado en 1993

The mitochondrial K(ATP) channel--fact or fiction?

artículo científico publicado en 2012

The mitochondrial permeability transition: a current perspective on its identity and role in ischaemia/reperfusion injury.

artículo científico

The mitochondrial phosphate carrier interacts with cyclophilin D and may play a key role in the permeability transition

artículo científico publicado en 2008

The mitochondrial pyruvate carrier. Kinetics and specificity for substrates and inhibitors ⬇️

artículo científico publicado el 1 de abril de 1975

The monocarboxylate transporter family—Role and regulation ⬇️

artículo científico publicado el 9 de diciembre de 2011

The monocarboxylate transporter family—Structure and functional characterization ⬇️

artículo científico publicado el 30 de noviembre de 2011

The nature of the changes in liver mitochondrial function induced by glucagon treatment of rats. The effects of intramitochondrial volume, aging and benzyl alcohol

artículo científico publicado en 1982

The nature of the stimulation of the respiratory chain of rat liver mitochondria by glucagon pretreatment of animals

artículo científico publicado en 1982

The neuroplastin adhesion molecules are accessory proteins that chaperone the monocarboxylate transporter MCT2 to the neuronal cell surface

artículo científico publicado en 2013

The pathway of electron flow through ubiquinol:cytochrome c oxidoreductase in the respiratory chain. Evidence from inhibition studies for a modified ‘Q cycle’ ⬇️

artículo científico publicado el 15 de abril de 1982

The permeability transition pore complex: another view.

artículo científico publicado en 2002

The plasma membrane lactate transporter MCT4, but not MCT1, is up-regulated by hypoxia through a HIF-1alpha-dependent mechanism.

artículo científico publicado en 2006

The proton-linked monocarboxylate transporter (MCT) family: structure, function and regulation

artículo científico publicado en 1999

The regulation of branched-chain 2-oxo acid dehydrogenase of liver, kidney and heart by phosphorylation

artículo científico publicado en 1981

The regulation of the matrix volume of mammalian mitochondria in vivo and in vitro and its role in the control of mitochondrial metabolism

artículo científico

The regulation of the oxidation of fatty acids and other substrates in rat heart mitochondria by changes in the matrix volume induced by osmotic strength, valinomycin and Ca2+.

artículo científico publicado en 1987

The role of charged residues in the transmembrane helices of monocarboxylate transporter 1 and its ancillary protein basigin in determining plasma membrane expression and catalytic activity

artículo científico publicado en 2006

The role of hexokinase in cardioprotection - mechanism and potential for translation

artículo científico publicado en 2015

The role of mitochondria in protection of the heart by preconditioning.

artículo científico publicado en 2007

The role of oxidized cytochrome c in regulating mitochondrial reactive oxygen species production and its perturbation in ischaemia

scientific journal article

The role of the mitochondrial permeability transition pore in heart disease.

artículo científico publicado en 2009

The roles of phosphate and the phosphate carrier in the mitochondrial permeability transition pore

artículo científico publicado en 2012

The rôle of mitochondrial pyruvate transport in the stimulation by glucagon and phenylephrine of gluconeogenesis from L-lactate in isolated rat hepatocytes

artículo científico publicado en 1981

The specificity and metabolic implications of the inhibition of pyruvate transport in isolated mitochondria and intact tissue preparations by alpha-Cyano-4-hydroxycinnamate and related compounds

artículo científico publicado en 1975

Transport Activity of the High-affinity Monocarboxylate Transporter MCT2 Is Enhanced by Extracellular Carbonic Anhydrase IV but Not by Intracellular Carbonic Anhydrase II ⬇️

artículo científico publicado el 16 de junio de 2011

Transport of lactate and other monocarboxylates across mammalian plasma membranes

artículo científico publicado en 1993

Transport of pyruvate nad lactate into human erythrocytes. Evidence for the involvement of the chloride carrier and a chloride-independent carrier ⬇️

artículo científico publicado el 15 de mayo de 1976

Tumour necrosis factor-alpha activation of protein kinase B in WEHI-164 cells is accompanied by increased phosphorylation of Ser473, but not Thr308

artículo científico publicado en 2001

UCPs--unlikely calcium porters.

artículo científico publicado en 2008

Upregulation of the cardiac monocarboxylate transporter MCT1 in a rat model of congestive heart failure

artículo científico publicado en 2001

Urocortin prevents mitochondrial permeability transition in response to reperfusion injury indirectly by reducing oxidative stress

artículo científico publicado en 2007

cDNA cloning of rat mitochondrial cyclophilin.

artículo científico publicado en 1997

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