Filtros de búsqueda

Lista de obras de Frédéric Checler

6-Hydroxydopamine but not 1-methyl-4-phenylpyridinium abolishes alpha-synuclein anti-apoptotic phenotype by inhibiting its proteasomal degradation and by promoting its aggregation

artículo científico publicado en 2006

A survey of the cerebral regionalization and ontogeny of eight exo- and endopeptidases in murines

artículo científico publicado en 1993

ADAM30 Downregulates APP-Linked Defects Through Cathepsin D Activation in Alzheimer's Disease

artículo científico publicado en 2016

APH1 polar transmembrane residues regulate the assembly and activity of presenilin complexes

scientific article published on 15 April 2009

APPepsilon, the epsilon-secretase-derived N-terminal product of the beta-amyloid precursor protein, behaves as a type I protein and undergoes alpha-, beta-, and gamma-secretase cleavages

artículo científico publicado en 2006

Alpha-synuclein and the Parkinson's disease-related mutant Ala53Thr-alpha-synuclein do not undergo proteasomal degradation in HEK293 and neuronal cells

artículo científico publicado en 2000

Alpha-synuclein lowers p53-dependent apoptotic response of neuronal cells. Abolishment by 6-hydroxydopamine and implication for Parkinson's disease

artículo científico publicado en 2002

Alterations of the Endoplasmic Reticulum (ER) Calcium Signaling Molecular Components in Alzheimer's Disease

artículo científico publicado en 2020

Alzheimer's and prion diseases: distinct pathologies, common proteolytic denominators.

artículo científico publicado en 2002

Alzheimer's disease-linked mutation of presenilin 2 (N141I-PS2) drastically lowers APPalpha secretion: control by the proteasome.

artículo científico publicado en 1998

Alzheimer's genetic risk factor FERMT2 (Kindlin-2) controls axonal growth and synaptic plasticity in an APP-dependent manner

artículo científico publicado en 2020

Aminopeptidase A contributes to the N-terminal truncation of amyloid beta-peptide

artículo científico publicado en 2009

Amyloid precursor protein, presenilins, and alpha-synuclein: molecular pathogenesis and pharmacological applications in Alzheimer's disease.

artículo científico publicado en 2002

Amyloid β production is regulated by β2-adrenergic signaling-mediated post-translational modifications of the ryanodine receptor.

artículo científico publicado en 2017

Amyloid-beta42 is preferentially accumulated in muscle fibers of patients with sporadic inclusion-body myositis

artículo científico publicado en 2009

Apoptosis in Parkinson's disease: Is p53 the missing link between genetic and sporadic Parkinsonism? ⬇️

artículo científico publicado el 20 de octubre de 2010

Are N- and C-terminally truncated Aβ species key pathological triggers in Alzheimer's disease?

artículo científico publicado en 2018

Aβ42 oligomers modulate β-secretase through an XBP-1s-dependent pathway involving HRD1.

artículo científico publicado en 2016

BACE1 is at the crossroad of a toxic vicious cycle involving cellular stress and β-amyloid production in Alzheimer's disease

artículo científico publicado en 2012

BACE1- and BACE2-expressing human cells: characterization of beta-amyloid precursor protein-derived catabolites, design of a novel fluorimetric assay, and identification of new in vitro inhibitors

artículo científico publicado en 2003

Behavioral alterations associated with apoptosis and down-regulation of presenilin 1 in the brains of p53-deficient mice

artículo científico publicado en 2000

Behavioral disturbances without amyloid deposits in mice overexpressing human amyloid precursor protein with Flemish (A692G) or Dutch (E693Q) mutation.

artículo científico publicado en 2000

C-terminal fragments of amyloid-beta peptide cause cholinergic axonal degeneration by a toxic effect rather than by physical injury in the nondemented human brain

artículo científico publicado en 2003

Caspase-3-derived C-terminal product of synphilin-1 displays antiapoptotic function via modulation of the p53-dependent cell death pathway.

artículo científico publicado en 2006

Catabolism of endogenous and overexpressed APH1a and PEN2: evidence for artifactual involvement of the proteasome in the degradation of overexpressed proteins

artículo científico publicado en 2006

Catabolism of neurotensin by neural (neuroblastoma clone N1E115) and extraneural (HT29) cell lines

artículo científico publicado en 1986

Cathepsin D displays in vitro beta-secretase-like specificity.

artículo científico publicado en 1997

Cellular prion protein sensitizes neurons to apoptotic stimuli through Mdm2-regulated and p53-dependent caspase 3-like activation

artículo científico publicado en 2003

Cerebrospinal Aβ11-x and 17-x levels as indicators of mild cognitive impairment and patients' stratification in Alzheimer's disease.

artículo científico publicado en 2013

Chronic fornix deep brain stimulation in a transgenic Alzheimer's rat model reduces amyloid burden, inflammation, and neuronal loss

artículo científico publicado en 2018

Combined pharmacological, mutational and cell biology approaches indicate that p53-dependent caspase 3 activation triggered by cellular prion is dependent on its endocytosis.

artículo científico publicado en 2005

Comparison of some biological properties of neurotensin and its natural analogue LANT-6.

artículo científico publicado en 1984

Confocal microscopy reveals thimet oligopeptidase (EC 3.4.24.15) and neurolysin (EC 3.4.24.16) in the classical secretory pathway.

artículo científico publicado en 1999

Constitutive alpha-secretase cleavage of the beta-amyloid precursor protein in the furin-deficient LoVo cell line: involvement of the pro-hormone convertase 7 and the disintegrin metalloprotease ADAM10.

artículo científico publicado en 2001

Contribution of endopeptidase 3.4.24.15 to central neurotensin inactivation

artículo científico publicado en 1997

Correction to: Alzheimer's genetic risk factor FERMT2 (Kindlin-2) controls axonal growth and synaptic plasticity in an APP-dependent manner

scientific article published on 04 January 2021

Cyclooxygenase-2 in the hippocampus is up-regulated in Alzheimer's disease but not in variant Alzheimer's disease with cotton wool plaques in humans

artículo científico publicado en 2003

Days to criterion as an indicator of toxicity associated with human Alzheimer amyloid-beta oligomers

artículo científico publicado en 2010

Degradation of Neurotensin by Rat Brain Synaptic Membranes: Involvement of a Thermolysin-Like Metalloendopeptidase (Enkephalinase), Angiotensin-Converting Enzyme, and Other Unidentified Peptidases ⬇️

artículo científico publicado el 1 de agosto de 1983

Design and characterization of a new cell-permeant inhibitor of the beta-secretase BACE1.

artículo científico publicado en 2005

Design and characterization of a novel cellular prion-derived quenched fluorimetric substrate of alpha-secretase

artículo científico publicado en 2006

Direct α-synuclein promoter transactivation by the tumor suppressor p53.

artículo científico publicado en 2016

Does Intraneuronal Accumulation of Carboxyl-terminal Fragments of the Amyloid Precursor Protein Trigger Early Neurotoxicity in Alzheimer's Disease?

scientific article published on 01 January 2019

ER-stress-associated functional link between Parkin and DJ-1 via a transcriptional cascade involving the tumor suppressor p53 and the spliced X-box binding protein XBP-1.

artículo científico publicado en 2013

ERK1-independent α-secretase cut of β-amyloid precursor protein via M1 muscarinic receptors and PKCα/ε.

artículo científico publicado en 2011

Effect of protein kinase A inhibitors on the production of Abeta40 and Abeta42 by human cells expressing normal and Alzheimer's disease-linked mutated betaAPP and presenilin 1.

artículo científico publicado en 1999

Endogenous beta-amyloid production in presenilin-deficient embryonic mouse fibroblasts

artículo científico publicado en 2001

Endopeptidase 24-16 in murines: tissue distribution, cerebral regionalization, and ontogeny.

artículo científico publicado en 1992

Eph receptors: new players in Alzheimer's disease pathogenesis.

artículo científico publicado en 2014

Evidence that the amyloid-β protein precursor intracellular domain, AICD, derives from β-secretase-generated C-terminal fragment

artículo científico publicado en 2012

Examination of the role of endopeptidase 3.4.24.15 in A beta secretion by human transfected cells.

artículo científico publicado en 1997

Experimental stroke: neurolysin back on stage

artículo científico publicado en 2014

Further characterization of a neurotensin-degrading neutral metalloendopeptidase from rat brain

artículo científico publicado en 1988

Further characterization of a putative serine protease contributing to the γ-secretase cleavage of β-amyloid precursor protein

scholarly article by Marine Peuchmaur published in February 2013

Gamma-secretase-like cleavages of Notch and beta APP are mutually exclusive in human cells

artículo científico publicado en 2002

Glioma tumor grade correlates with parkin depletion in mutant p53-linked tumors and results from loss of function of p53 transcriptional activity.

artículo científico

High-affinity receptor sites and rapid proteolytic inactivation of neurotensin in primary cultured neurons

artículo científico publicado en 1986

Human amyloid-beta causes changes in the levels of endothelial protein kinase C and its alpha isoform in vitro

artículo científico publicado en 2002

Immunohistochemical Analysis of Cerebral Cortical and Vascular Lesions in the Primate Microcebus murinus Reveal Distinct Amyloid β1–42 and β1–40 Immunoreactivity Profiles

artículo científico publicado en 2000

Inactivation of neurotensin by rat brain synaptic membranes partly occurs through cleavage at the Arg8-Arg9 peptide bond by a metalloendopeptidase

artículo científico publicado en 1985

Inactivation of neurotensin by rat brain synaptic membranes. Cleavage at the Pro10-Tyr11 bond by endopeptidase 24.11 (enkephalinase) and a peptidase different from proline-endopeptidase

artículo científico publicado en 1984

Increased expression of neuronal cyclooxygenase-2 in the hippocampus in amyotrophic lateral sclerosis both with and without dementia

artículo científico publicado en 2004

Influence of Genetic Background on Apathy-Like Behavior in Triple Transgenic AD Mice

artículo científico publicado en 2016

Insulin stimulation of amino acid transport in primary cultured rat hepatocytes varies in direct proportion to insulin binding

scientific article published on 01 June 1981

Interplay between parkin and p53 governs a physiological homeostasis that is disrupted in Parkinson's disease and cerebral cancer.

artículo científico publicado en 2013

Intracellular Abeta42 activates p53 promoter: a pathway to neurodegeneration in Alzheimer's disease

artículo científico publicado en 2004

Intraneuronal Abeta42 accumulation in human brain.

artículo científico publicado en 2000

Intraneuronal accumulation of C99 contributes to synaptic alterations, apathy-like behavior, and spatial learning deficits in 3×TgAD and 2×TgAD mice

scientific article published on 12 July 2018

Intraneuronal aggregation of the β-CTF fragment of APP (C99) induces Aβ-independent lysosomal-autophagic pathology.

artículo científico publicado en 2016

Isoform-specific contribution of protein kinase C to prion processing.

artículo científico publicado en 2008

JLK isocoumarin inhibitors: selective gamma-secretase inhibitors that do not interfere with notch pathway in vitro or in vivo

artículo científico publicado en 2003

Journal of Neurochemistry special issue on Alzheimer's disease: 'amyloid cascade hypothesis--20 years on'.

artículo científico publicado en 2011

Laminar specific loss of isocortical presenilin 1 immunoreactivity in Alzheimer's disease. Correlations with the amyloid load and the density of tau-positive neurofibrillary tangles.

artículo científico publicado en 2000

Light and Electron Microscopic Localization of the Neutral Metalloendopeptidase EC 3.4.24.16 in the Mesencephalon of the Rat.

artículo científico publicado en 1992

Localization and Processing of the Amyloid-β Protein Precursor in Mitochondria-Associated Membranes.

artículo científico publicado en 2016

Loss of function of DJ-1 triggered by Parkinson's disease-associated mutation is due to proteolytic resistance to caspase-6.

scientific article published on January 2010

Loss of high affinity neurotensin receptors in substantia nigra from parkinsonian subjects

artículo científico publicado en 1984

Lysosomal dysfunction in a mouse model of Sandhoff disease leads to accumulation of ganglioside-bound amyloid-β peptide

artículo científico publicado en 2012

M1 and M3 muscarinic receptors control physiological processing of cellular prion by modulating ADAM17 phosphorylation and activity.

artículo científico publicado en 2007

MT5-MMP is a new pro-amyloidogenic proteinase that promotes amyloid pathology and cognitive decline in a transgenic mouse model of Alzheimer's disease.

artículo científico publicado en 2015

Melatonin stimulates the nonamyloidogenic processing of βAPP through the positive transcriptional regulation of ADAM10 and ADAM17.

artículo científico publicado en 2014

Monoclonal antibodies allow precipitation of esterasic but not peptidasic activities associated with butyrylcholinesterase

scientific article published on 01 September 1990

Murine T cells expressing high activity of prolyl endopeptidase are susceptible to activation-induced cell death

artículo científico publicado en 2002

Mutant presenilin 1 increases the levels of Alzheimer amyloid beta-peptide Abeta42 in late compartments of the constitutive secretory pathway.

artículo científico publicado en 2000

N-truncated Aβ peptides in complex fluids unraveled by new specific immunoassays

artículo científico publicado en 2012

NFkappaB-dependent control of BACE1 promoter transactivation by Abeta42.

artículo científico publicado en 2008

Neprilysin activity and expression are controlled by nicastrin

artículo científico publicado en 2006

Neurolysin: From Initial Detection to Latest Advances

artículo científico publicado en 2018

Neuromedin N: high affinity interaction with brain neurotensin receptors and rapid inactivation by brain synaptic peptidases

artículo científico publicado en 1986

Neuropathology of preclinical and clinical late-onset Alzheimer's disease

artículo científico publicado en 1998

Neuropeptide specificity and inhibition of recombinant isoforms of the endopeptidase 3.4.24.16 family: comparison with the related recombinant endopeptidase 3.4.24.15.

artículo científico publicado en 1998

Neurotensin and neuromedin N are differently metabolized in ventral tegmental area and nucleus accumbens

artículo científico publicado en 1991

Neurotensin and neuromedin N undergo distinct catabolic processes in murine astrocytes and primary cultured neurons

artículo científico publicado en 1994

Neurotensin and neuromedin N undergo distinct proteolytic inactivation in ventral tegmental area and nucleus accumbens

artículo científico publicado en 1992

Neurotensin metabolism in various tissues of central and peripheral origins: ubiquitous involvement of a novel neurotensin degrading metalloendopeptidase

artículo científico publicado en 1988

Neurotensin receptor localization on neurons bearing the neurotensin-degrading enzyme endopeptidase 24-16.

artículo científico publicado en 1992

Neurotensin-metabolizing peptidases in rat fundus plasma membranes

artículo científico publicado en 1987

New protease inhibitors prevent gamma-secretase-mediated production of Abeta40/42 without affecting Notch cleavage

artículo científico publicado en 2001

Non-cholinergic actions of acetylcholinesterases: a genuine peptidase function or contaminating proteases?

artículo científico publicado en 1990

Novel proline endopeptidase inhibitors do not modify Abeta40/42 formation and degradation by human cells expressing wild-type and swedish mutated beta-amyloid precursor protein

artículo científico publicado en 2000

Nuclear TP53: An unraveled function as transcriptional repressor of PINK1

artículo científico publicado en 2018

Nuclear factor-κB regulates βAPP and β- and γ-secretases differently at physiological and supraphysiological Aβ concentrations

artículo científico publicado en 2012

Nuclear factor-κB regulates βAPP and β- and γ-secretases differently at physiological and supraphysiological Aβ concentrations

artículo científico publicado en 2015

Nuclear factor-κB regulates βAPP and β- and γ-secretases differently at physiological and supraphysiological Aβ concentrations

scientific article published in 2013

Nuclear p53-mediated repression of autophagy involves PINK1 transcriptional down-regulation

artículo científico publicado en 2018

Overexpression of PrPc triggers caspase 3 activation: potentiation by proteasome inhibitors and blockade by anti-PrP antibodies

artículo científico publicado en 2002

Overexpression of Rab11 or constitutively active Rab11 does not affect sAPPalpha and Abeta secretions by wild-type and Swedish mutated betaAPP-expressing HEK293 cells.

artículo científico publicado en 2000

Parkin differently regulates presenilin-1 and presenilin-2 functions by direct control of their promoter transcription

artículo científico publicado en 2013

Pathogenic APP mutations near the gamma-secretase cleavage site differentially affect Abeta secretion and APP C-terminal fragment stability.

artículo científico publicado en 2001

Peptidasic activities associated with acetylcholinesterase are due to contaminating enzymes

scientific article published on 01 September 1989

Peripheral inactivation of neurotensin. Isolation and characterization of a metallopeptidase from rat ileum ⬇️

artículo científico publicado el 15 de agosto de 1988

Pharmacological evidences for DFK167-sensitive presenilin-independent gamma-secretase-like activity

artículo científico publicado en 2009

Phenotype associated with APP duplication in five families

artículo científico publicado en 2006

Phorbol ester-regulated cleavage of normal prion protein in HEK293 human cells and murine neurons

artículo científico publicado en 2000

Post-translational remodeling of ryanodine receptor induces calcium leak leading to Alzheimer's disease-like pathologies and cognitive deficits

artículo científico publicado en 2017

Presenilin 1 and Presenilin 2 Target γ-Secretase Complexes to Distinct Cellular Compartments

artículo científico publicado en 2016

Presenilin 2 deficiency causes a mild pulmonary phenotype and no changes in amyloid precursor protein processing but enhances the embryonic lethal phenotype of presenilin 1 deficiency

scientific journal article

Presenilin-dependent gamma-secretase-mediated control of p53-associated cell death in Alzheimer's disease.

artículo científico publicado en 2006

Presenilin-dependent transcriptional control of the Abeta-degrading enzyme neprilysin by intracellular domains of betaAPP and APLP

scientific journal article

Presenilin-directed inhibitors of gamma-secretase trigger caspase 3 activation in presenilin-expressing and presenilin-deficient cells

artículo científico publicado en 2004

Presenilins at the crossroad of a functional interplay between PARK2/PARKIN and PINK1 to control mitophagy: Implication for neurodegenerative diseases

artículo científico publicado en 2017

Presenilins: structural aspects and posttranslational events.

artículo científico publicado en 1999

Primary cultured neurons devoid of cellular prion display lower responsiveness to staurosporine through the control of p53 at both transcriptional and post-transcriptional levels

artículo científico publicado en 2003

Proamyloidogenic effects of membrane type 1 matrix metalloproteinase involve MMP-2 and BACE-1 activities, and the modulation of APP trafficking

artículo científico publicado en 2018

Production and catabolism of amyloid peptides in Alzheimer's disease ⬇️

artículo científico publicado el 1 de septiembre de 2010

Production and fate of amyloid peptides: recent advances and perspectives.

artículo científico publicado en 2008

Prominent cerebral amyloid angiopathy in transgenic mice overexpressing the london mutant of human APP in neurons.

artículo científico publicado en 2000

Pyk2 overexpression in postsynaptic neurons blocks amyloid β<sub>1-42</sub>-induced synaptotoxicity in microfluidic co-cultures

scientific article published on 28 August 2020

Rat kidney endopeptidase 24.16. Purification, physico-chemical characteristics and differential specificity towards opiates, tachykinins and neurotensin-related peptides

artículo científico publicado en 1993

Regulation of cyclic GMP levels by neurotensin in neuroblastoma clone N1E115.

artículo científico publicado en 1985

Response to Correspondence: Pardossi-Piquard et al., “Presenilin-Dependent Transcriptional Control of the Aβ-Degrading Enzyme Neprilysin by Intracellular Domains of βAPP and APLP.” Neuron 46, 541–554

article

Role of the proteasome in Alzheimer’s disease

Ryanodine receptors: dual contribution to Alzheimer disease?

artículo científico publicado en 2014

Ryanodine receptors: physiological function and deregulation in Alzheimer disease.

artículo científico publicado en 2014

S 17092-1, a highly potent, specific and cell permeant inhibitor of human proline endopeptidase.

artículo científico publicado en 1999

Sox2 functionally interacts with βAPP, the βAPP intracellular domain and ADAM10 at a transcriptional level in human cells

artículo científico publicado en 2015

Specific inhibition of endopeptidase 24.16 by dipeptides

artículo científico publicado en 1991

Study on Aβ34 biology and detection in transgenic mice brains

scientific article published on 11 January 2014

Study on the putative contribution of caspases and the proteasome to the degradation of Aph-1a and Pen-2.

artículo científico publicado en 2007

Synthesis and analgesic effects of N-[3-[(hydroxyamino) carbonyl]-1-oxo-2(R)-benzylpropyl]-L-isoleucyl-L-leucine, a new potent inhibitor of multiple neurotensin/neuromedin N degrading enzymes.

artículo científico publicado en 1993

Synthesis of new 3-alkoxy-7-amino-4-chloro-isocoumarin derivatives as new beta-amyloid peptide production inhibitors and their activities on various classes of protease

artículo científico publicado en 2003

TMP21 is a presenilin complex component that modulates gamma-secretase but not epsilon-secretase activity

artículo científico publicado en 2006

TMP21 regulates Abeta production but does not affect caspase-3, p53, and neprilysin

artículo científico publicado en 2008

TMP21 transmembrane domain regulates gamma-secretase cleavage

artículo científico publicado en 2009

The C-terminal fragment of presenilin 2 triggers p53-mediated staurosporine-induced apoptosis, a function independent of the presenilinase-derived N-terminal counterpart

artículo científico publicado en 2003

The C-terminal fragment of the Alzheimer's disease amyloid protein precursor is degraded by a proteasome-dependent mechanism distinct from gamma-secretase

artículo científico publicado en 2001

The C-terminal products of cellular prion protein processing, C1 and C2, exert distinct influence on p53-dependent staurosporine-induced caspase-3 activation.

artículo científico publicado en 2006

The Endoplasmic Reticulum Stress/Unfolded Protein Response and Their Contributions to Parkinson's Disease Physiopathology

artículo científico publicado en 2020

The OncoAge Consortium: Linking Aging and Oncology from Bench to Bedside and Back Again

scientific article published on 21 February 2019

The Polyherbal Wattana Formula Displays Anti-Amyloidogenic Properties by Increasing α-Secretase Activities

artículo científico publicado en 2017

The Transcription Factor Function of Parkin: Breaking the Dogma

artículo científico publicado en 2018

The alpha-secretase-derived N-terminal product of cellular prion, N1, displays neuroprotective function in vitro and in vivo

artículo científico publicado en 2009

The caspase-derived C-terminal fragment of betaAPP induces caspase-independent toxicity and triggers selective increase of Abeta42 in mammalian cells

artículo científico publicado en 2001

The disintegrin ADAM9 indirectly contributes to the physiological processing of cellular prion by modulating ADAM10 activity

artículo científico publicado en 2005

The extracellular regulated kinase-1 (ERK1) controls regulated alpha-secretase-mediated processing, promoter transactivation, and mRNA levels of the cellular prion protein.

artículo científico publicado en 2011

The extracellular regulated kinase-1 (ERK1) controls regulated α-secretase-mediated processing, promoter transactivation, and mRNA levels of the cellular prion protein

artículo científico publicado en 2013

The gamma/epsilon-secretase-derived APP intracellular domain fragments regulate p53.

artículo científico publicado en 2007

The physiology of the β-amyloid precursor protein intracellular domain AICD.

artículo científico publicado en 2011

The presenilin mystery. The research winner-by-a knockout?

artículo científico publicado en 1999

The transcription factor X-box binding protein-1 in neurodegenerative diseases

artículo científico

The transcription factor XBP1 in memory and cognition: Implications in Alzheimer disease

artículo científico publicado en 2017

The transcription factor XBP1s restores hippocampal synaptic plasticity and memory by control of the Kalirin-7 pathway in Alzheimer model

artículo científico publicado en 2016

The β-secretase-derived C-terminal fragment of βAPP, C99, but not Aβ, is a key contributor to early intraneuronal lesions in triple-transgenic mouse hippocampus

artículo científico publicado en 2012

Transcriptional repression of p53 by parkin and impairment by mutations associated with autosomal recessive juvenile Parkinson's disease.

artículo científico publicado en 2009

Two-steps control of cellular prion physiology by the extracellular regulated kinase-1 (ERK1)

artículo científico publicado en 2012

Unusual phenotypic alteration of beta amyloid precursor protein (betaAPP) maturation by a new Val-715 --> Met betaAPP-770 mutation responsible for probable early-onset Alzheimer's disease

artículo científico publicado en 1999

Variability and heterogeneity in Alzheimer's disease with cotton wool plaques: a clinicopathological study of four autopsy cases

artículo científico publicado en 2003

Vascular and parenchymal Abeta deposition in the aging dog: correlation with behavior.

artículo científico publicado en 2000

Visualization of specific γ-secretase complexes using bimolecular fluorescence complementation

artículo científico publicado en 2014

Wild-type and mutated nicastrins do not display aminopeptidase M- and B-like activities.

artículo científico publicado en 2001

[Radioactive analogs of neurotensin. II. Preparation of tritiated neurotensin from a synthetic multi-unsaturated derivative].

artículo científico publicado en 1983

[TRP11]-neurotensin and xenopsin discriminate between rat and guinea-pig neurotensin receptors

artículo científico publicado en 1982

p53-Dependent Aph-1 and Pen-2 anti-apoptotic phenotype requires the integrity of the gamma-secretase complex but is independent of its activity

artículo científico publicado en 2007

p53-Dependent transcriptional control of cellular prion by presenilins. ⬇️

artículo científico publicado en 2009

p53-dependent control of cell death by nicastrin: lack of requirement for presenilin-dependent gamma-secretase complex

artículo científico publicado en 2009

p53-dependent control of transactivation of the Pen2 promoter by presenilins

artículo científico publicado en 2009

α-Secretase-derived fragment of cellular prion, N1, protects against monomeric and oligomeric amyloid β (Aβ)-associated cell death

artículo científico publicado en 2013

α-synuclein and p53 functional interplay in physiopathological contexts.

artículo científico publicado en 2016

β-Amyloid Precursor Protein Intracellular Domain Controls Mitochondrial Function by Modulating Phosphatase and Tensin Homolog-Induced Kinase 1 Transcription in Cells and in Alzheimer Mice Models

artículo científico publicado en 2017

γ-Secretase-mediated regulation of neprilysin: influence of cell density and aging and modulation by imatinib

artículo científico publicado en 2011

Dominio Público Uruguay está sostenido por:

Acerca de Dominio Público Uruguay

Ayuda