Lista de obras - Albert Duschl - Dominio Público Uruguay

A Novel Exposure System Termed NAVETTA for In Vitro Laminar Flow Electrodeposition of Nanoaerosol and Evaluation of Immune Effects in Human Lung Reporter Cells

artículo científico publicado en 2017

A comparison of assays for the response of primary human T-cells upon stimulation with interleukin-2, interleukin-4 and interleukin-7.

artículo científico publicado en 1992

A high-throughput screening method based on stably transformed human cells was used to determine the immunotoxic effects of fluoranthene and other PAHs.

artículo científico publicado en 2008

A murine interleukin-4 antagonistic mutant protein completely inhibits interleukin-4-induced cell proliferation, differentiation, and signal transduction

artículo científico publicado en 1997

A survey on the state of nanosafety research in the European Union and the United States

Active induction of tumor-specific IgE antibodies by oral mimotope vaccination

artículo científico publicado en 2007

Air Pollution and Climate Change Effects on Allergies in the Anthropocene: Abundance, Interaction, and Modification of Allergens and Adjuvants.

artículo científico publicado en 2017

Altered characteristics of silica nanoparticles in bovine and human serum: the importance of nanomaterial characterization prior to its toxicological evaluation

artículo científico publicado en 2013

An antagonistic IL-4 mutant prevents type I allergy in the mouse: inhibition of the IL-4/IL-13 receptor system completely abrogates humoral immune response to allergen and development of allergic symptoms in vivo

scientific article published on 01 April 1998

An antagonistic mutant of interleukin-4 fails to recruit gamma c into the receptor complex. Characterization by specific crosslinking

artículo científico publicado en 1995

An efficient system for the synthesis of bacteriorhodopsin in Halobacterium halobium

artículo científico publicado en 1990

Anion binding to the chloride pump, halorhodopsin, and its implications for the transport mechanism ⬇️

artículo científico publicado el 4 de junio de 1990

Antagonistic mutant proteins of interleukin-4.

artículo científico publicado en 1995

Antibody microarray-based profiling of complex specimens: systematic evaluation of labeling strategies

artículo científico publicado en 2007

Assessment of a panel of interleukin-8 reporter lung epithelial cell lines to monitor the pro-inflammatory response following zinc oxide nanoparticle exposure under different cell culture conditions

artículo científico publicado en 2015

Bacterial endotoxin (lipopolysaccharide) binds to the surface of gold nanoparticles, interferes with biocorona formation and induces human monocyte inflammatory activation.

artículo científico publicado en 2017

Biocompatible micro-sized cell culture chamber for the detection of nanoparticle-induced IL8 promoter activity on a small cell population

artículo científico publicado en 2011

Biological Activity of Masked Endotoxin

artículo científico publicado en 2017

Biological reactivity of zinc oxide nanoparticles with mammalian test systems: an overview.

artículo científico

Both interleukin 4 and interleukin 13 induce tyrosine phosphorylation of the 140-kDa subunit of the interleukin 4 receptor

scientific article published on 01 January 1995

Bovine Serum Albumin Adsorption on TiO2 Colloids: The Effect of Particle Agglomeration and Surface Composition.

artículo científico publicado en 2017

Characterization of intrinsic and extrinsic risk factors for celery allergy in immunosenescence

artículo científico publicado en 2007

Chitosan functionalisation of gold nanoparticles encourages particle uptake and induces cytotoxicity and pro-inflammatory conditions in phagocytic cells, as well as enhancing particle interactions with serum components

artículo científico publicado en 2015

Chlorobenzene induces the NF-kappa B and p38 MAP kinase pathways in lung epithelial cells

artículo científico publicado en 2008

Copper oxide nanoparticle toxicity profiling using untargeted metabolomics

artículo científico publicado en 2016

Correction to: Particle toxicology and health - where are we?

scientific article published on 27 June 2019

Current Trends in Nanoeducation for Industry and Society

Cytokine antagonists and allergy

artículo científico publicado en 1998

Dendritic cells activated by IFN-γ/STAT1 express IL-31 receptor and release proinflammatory mediators upon IL-31 treatment.

artículo científico

Determination of nitration degrees for the birch pollen allergen Bet v 1

artículo científico publicado en 2013

Development of an on-line exposure system to determine freshly produced diesel engine emission-induced cellular effects.

artículo científico publicado en 2013

Differential pro-inflammatory effects of metal oxide nanoparticles and their soluble ions in vitro and in vivo; zinc and copper nanoparticles, but not their ions, recruit eosinophils to the lungs

artículo científico publicado en 2011

Dispersion medium modulates oxidative stress response of human lung epithelial cells upon exposure to carbon nanomaterial samples.

artículo científico publicado en 2009

Early hematological and immunological alterations in gasoline station attendants exposed to benzene

artículo científico publicado en 2015

Enhanced Deposition by Electrostatic Field-Assistance Aggravating Diesel Exhaust Aerosol Toxicity for Human Lung Cells.

artículo científico publicado en 2015

Enzyme adsorption-induced activity changes: a quantitative study on TiO2 model agglomerates.

artículo científico publicado en 2017

Functional reconstitution of halorhodopsin. Properties of halorhodopsin-containing proteoliposomes

artículo científico publicado en 1988

Hardening of the nanoparticle-protein corona in metal (Au, Ag) and oxide (Fe3O4, CoO, and CeO2) nanoparticles.

artículo científico publicado en 2011

Human Th2 but not Th9 cells release IL-31 in a STAT6/NF-κB-dependent way.

artículo científico

IL-1β induces expression of costimulatory molecules and cytokines but not immune feedback regulators in dendritic cells

scientific article published on 07 June 2018

IL-4 and IL-13 induce SOCS-1 gene expression in A549 cells by three functional STAT6-binding motifs located upstream of the transcription initiation site

artículo científico publicado en 2003

IL-4 induces expression of TARC/CCL17 via two STAT6 binding sites

artículo científico publicado en 2006

IL-4 receptor complexes containing or lacking the gamma C chain are inhibited by an overlapping set of antagonistic IL-4 mutant proteins

artículo científico publicado en 1997

Identification of a distal tandem STAT6 element within the CCL17 locus

artículo científico publicado en 2007

Immune Effects of the Nitrated Food Allergen Beta-Lactoglobulin in an Experimental Food Allergy Model

artículo científico publicado en 2019

Impact of nanosilver on various DNA lesions and HPRT gene mutations - effects of charge and surface coating

artículo científico publicado en 2015

In vitro investigation of immunomodulatory effects caused by engineered inorganic nanoparticles – the impact of experimental design and cell choice

scholarly article by Tobias Pfaller et al published January 2009 in Nanotoxicology

Inhibiting the IL-4 receptor: why, how, and for whom?

scientific article published on 01 September 2000

Inhibition of suppressive T cell factor 1 (TCF-1) isoforms in naive CD4+ T cells is mediated by IL-4/STAT6 signaling

artículo científico publicado en 2010

Inhibition of the IL-4/IL-13 receptor system prevents allergic sensitization without affecting established allergy in a mouse model for allergic asthma

artículo científico publicado en 2003

Interaction of differently functionalized fluorescent silica nanoparticles with neural stem- and tissue-type cells

artículo científico publicado en 2013

Interaction of nanoparticles with proteins: relation to bio-reactivity of the nanoparticle.

scientific article published on 19 July 2013

Interactions between effects of environmental chemicals and natural stressors: a review

artículo científico publicado en 2009

Interactions of TiO2 Nanoparticles with Ingredients from Modern Lifestyle Products and Their Effects on Human Skin Cells

artículo científico publicado en 2020

Interconversions of the M, N, and O intermediates in the bacteriorhodopsin photocycle.

artículo científico publicado en 1990

Interleukin-13 selectively induces monocyte chemoattractant protein-1 synthesis and secretion by human endothelial cells. Involvement of IL-4R alpha and Stat6 phosphorylation

scientific article published on 01 July 1997

Interleukin-4 upregulates the heat shock protein Hsp90alpha and enhances transcription of a reporter gene coupled to a single heat shock element

artículo científico publicado en 1996

Is the toxic potential of nanosilver dependent on its size?

artículo científico publicado en 2014

JAK/STAT-dependent gene regulation by cytokines.

artículo científico publicado en 2005

LEF-1 negatively controls interleukin-4 expression through a proximal promoter regulatory element

artículo científico publicado en 2008

MUTZ-3, a monocytic model cell line for interleukin-4 and lipopolysaccharide studies

artículo científico publicado en 1996

Mechanistic insights into silica nanoparticle–allergen interactions on antigen presenting cell function in the context of allergic reactions

artículo científico publicado en 2023

Mouse macrophage development in the absence of the common γ chain: defining receptor complexes responsible for IL-4 and IL-13 signaling

article

NOD1 modulates IL-10 signalling in human dendritic cells

artículo científico publicado en 2017

Nano-immunosafety: issues in assay validation

Nanomaterials in the Context of Type 2 Immune Responses-Fears and Potentials.

artículo científico publicado en 2017

Nanoparticle-allergen interactions mediate human allergic responses: protein corona characterization and cellular responses.

artículo científico publicado en 2016

Nanoparticles and innate immunity: new perspectives on host defence

artículo científico publicado en 2017

Nanotechnology-Based Vaccines for Allergen-Specific Immunotherapy: Potentials and Challenges of Conventional and Novel Adjuvants under Research

scientific article published on 20 May 2020

Nitrated food proteins induce a regulatory immune response associated with allergy prevention after oral exposure in a Balb/c mouse food allergy model

scientific article published on 01 October 2019

Nitration enhances the allergenic potential of proteins.

artículo científico publicado en 2006

Nitration of ovalbumin decreases the risk for sensitization via the oral route in a mouse food allergy model

artículo científico publicado en 2011

Nitration of the birch pollen allergen Bet v 1.0101: efficiency and site-selectivity of liquid and gaseous nitrating agents.

artículo científico

Nitration of the egg-allergen ovalbumin enhances protein allergenicity but reduces the risk for oral sensitization in a murine model of food allergy.

artículo científico publicado en 2010

Nitration of the pollen allergen bet v 1.0101 enhances the presentation of bet v 1-derived peptides by HLA-DR on human dendritic cells

artículo científico publicado en 2012

Nitration of β-Lactoglobulin but Not of Ovomucoid Enhances Anaphylactic Responses in Food Allergic Mice.

artículo científico publicado en 2015

Pan-European inter-laboratory studies on a panel of in vitro cytotoxicity and pro-inflammation assays for nanoparticles.

artículo científico publicado en 2016

Particle toxicology and health - where are we?

article

Patulin influences the expression of Th1/Th2 cytokines by activated peripheral blood mononuclear cells and T cells through depletion of intracellular glutathione

artículo científico publicado en 2008

Phytochemical inhibition of interleukin-4-activated Stat6 and expression of VCAM-1.

artículo científico publicado en 2002

Poly-lactic acid nanoparticles (PLA-NP) promote physiological modifications in lung epithelial cells and are internalized by clathrin-coated pits and lipid rafts

artículo científico publicado en 2017

Prerequisites for Functional Interleukin 31 Signaling and Its Feedback Regulation by Suppressor of Cytokine Signaling 3 (SOCS3).

artículo científico publicado en 2015

Primary and secondary chloride transport in Halobacterium halobium

artículo científico publicado en 1986

Problems and challenges in the development and validation of human cell-based assays to determine nanoparticle-induced immunomodulatory effects

artículo científico publicado en 2011

Properties and photochemistry of a halorhodopsin from the haloalkalophile, Natronobacterium pharaonis

artículo científico publicado en 1990

Recovering What Matters: High Protein Recovery after Endotoxin Removal from LPS-Contaminated Formulations Using Novel Anti-Lipid A Antibody Microparticle Conjugates

artículo científico publicado en 2023

Residual endotoxin contaminations in recombinant proteins are sufficient to activate human CD1c+ dendritic cells

artículo científico publicado en 2014

SOCS-1 and SOCS-3 inhibit IL-4 and IL-13 induced activation of Eotaxin-3/CCL26 gene expression in HEK293 cells

artículo científico publicado en 2005

STAT6-dependent and -independent mechanisms in Th2 polarization

artículo científico publicado en 2012

SWCNT suppress inflammatory mediator responses in human lung epithelium in vitro.

artículo científico publicado en 2008

Signaling mechanisms, interaction partners, and target genes of STAT6.

artículo científico publicado en 2006

Specific inhibition of interleukin-4-dependent Stat6 activation by an intracellularly delivered peptide

artículo científico publicado en 2001

Stabilization of the Dimeric Birch Pollen Allergen Bet v 1 Impacts Its Immunological Properties

artículo científico publicado en 2014

Structure, binding, and antagonists in the IL-4/IL-13 receptor system.

artículo científico publicado en 2002

Styrene induces an inflammatory response in human lung epithelial cells via oxidative stress and NF-kappaB activation.

artículo científico publicado en 2008

Suppressor of cytokine signaling 2 is a feedback inhibitor of TLR-induced activation in human monocyte-derived dendritic cells.

artículo científico publicado en 2011

TGFβ1 mimetic peptide modulates immune response to grass pollen allergens in mice

scientific article published on 20 November 2019

TLR8 and NOD signaling synergistically induce the production of IL-1β and IL-23 in monocyte-derived DCs and enhance the expression of the feedback inhibitor SOCS2.

artículo científico publicado en 2012

The Impact of Nanoparticles on Innate Immune Activation by Live Bacteria

scientific article published on 18 December 2020

The Interleukin-4-Receptor: From Recognition Mechanism to Pharmacological Target Structure

scientific article published on 01 August 2000

The cytotoxic effects of the organophosphates chlorpyrifos and diazinon differ from their immunomodulating effects

artículo científico publicado en 2009

The diesel exhaust component pyrene induces expression of IL-8 but not of eotaxin

artículo científico publicado en 2003

The environmental pollutant pyrene induces the production of IL-4

artículo científico publicado en 2000

The human IgE germline promoter is regulated by interleukin-4, interleukin-13, interferon-alpha and interferon-gamma via an interferon-gamma-activated site and its flanking regions

artículo científico publicado en 1996

The impact of nitration on the structure and immunogenicity of the major birch pollen allergen Bet v 1.0101.

artículo científico publicado en 2014

The impact of the route and frequency of antigen exposure on the IgE response in allergy

scientific article published on 01 April 2001

The interleukin-4/interleukin-13 receptor of human synovial fibroblasts: overexpression of the nonsignaling interleukin-13 receptor alpha2.

artículo científico publicado en 1998

The nanotopography of SiO<sub>2</sub> particles impacts the selectivity and 3D fold of bound allergens

artículo científico publicado en 2021

The oxidative potential of differently charged silver and gold nanoparticles on three human lung epithelial cell types.

artículo científico publicado en 2015

The primary structure of a halorhodopsin from Natronobacterium pharaonis. Structural, functional and evolutionary implications for bacterial rhodopsins and halorhodopsins.

artículo científico publicado en 1990

The protein corona suppresses the cytotoxic and pro-inflammatory response in lung epithelial cells and macrophages upon exposure to nanosilica

scientific article published on 05 March 2019

The role of B7 costimulation in benzene immunotoxicity and its potential association with cancer risk

artículo científico publicado en 2018

The suitability of different cellular in vitro immunotoxicity and genotoxicity methods for the analysis of nanoparticle-induced events

artículo científico publicado en 2010

Time evolution of the nanoparticle protein corona.

artículo científico publicado en 2010

Transmembrane and intracellular signalling by interleukin-4: receptor dimerization and beyond.

artículo científico publicado en 1996

Upon prolonged allergen exposure IL-4 and IL-4Ralpha knockout mice produce specific IgE leading to anaphylaxis

artículo científico publicado en 2001

When Would Immunologists Consider a Nanomaterial to be Safe? Recommendations for Planning Studies on Nanosafety

scientific article published on 02 April 2020

Workflows for automated downstream data analysis and visualization in large-scale computational mass spectrometry.

artículo científico publicado en 2015

Lista de obras de Albert Duschl

A Novel Exposure System Termed NAVETTA for In Vitro Laminar Flow Electrodeposition of Nanoaerosol and Evaluation of Immune Effects in Human Lung Reporter Cells

A comparison of assays for the response of primary human T-cells upon stimulation with interleukin-2, interleukin-4 and interleukin-7.

A high-throughput screening method based on stably transformed human cells was used to determine the immunotoxic effects of fluoranthene and other PAHs.

A murine interleukin-4 antagonistic mutant protein completely inhibits interleukin-4-induced cell proliferation, differentiation, and signal transduction

A survey on the state of nanosafety research in the European Union and the United States

Active induction of tumor-specific IgE antibodies by oral mimotope vaccination

Air Pollution and Climate Change Effects on Allergies in the Anthropocene: Abundance, Interaction, and Modification of Allergens and Adjuvants.

Altered characteristics of silica nanoparticles in bovine and human serum: the importance of nanomaterial characterization prior to its toxicological evaluation

An antagonistic IL-4 mutant prevents type I allergy in the mouse: inhibition of the IL-4/IL-13 receptor system completely abrogates humoral immune response to allergen and development of allergic symptoms in vivo

An antagonistic mutant of interleukin-4 fails to recruit gamma c into the receptor complex. Characterization by specific crosslinking

An efficient system for the synthesis of bacteriorhodopsin in Halobacterium halobium

Anion binding to the chloride pump, halorhodopsin, and its implications for the transport mechanism ⬇️

Antagonistic mutant proteins of interleukin-4.

Antibody microarray-based profiling of complex specimens: systematic evaluation of labeling strategies

Assessment of a panel of interleukin-8 reporter lung epithelial cell lines to monitor the pro-inflammatory response following zinc oxide nanoparticle exposure under different cell culture conditions

Bacterial endotoxin (lipopolysaccharide) binds to the surface of gold nanoparticles, interferes with biocorona formation and induces human monocyte inflammatory activation.

Biocompatible micro-sized cell culture chamber for the detection of nanoparticle-induced IL8 promoter activity on a small cell population

Biological Activity of Masked Endotoxin

Biological reactivity of zinc oxide nanoparticles with mammalian test systems: an overview.

Both interleukin 4 and interleukin 13 induce tyrosine phosphorylation of the 140-kDa subunit of the interleukin 4 receptor

Bovine Serum Albumin Adsorption on TiO2 Colloids: The Effect of Particle Agglomeration and Surface Composition.

Characterization of intrinsic and extrinsic risk factors for celery allergy in immunosenescence

Chitosan functionalisation of gold nanoparticles encourages particle uptake and induces cytotoxicity and pro-inflammatory conditions in phagocytic cells, as well as enhancing particle interactions with serum components

Chlorobenzene induces the NF-kappa B and p38 MAP kinase pathways in lung epithelial cells

Copper oxide nanoparticle toxicity profiling using untargeted metabolomics

Correction to: Particle toxicology and health - where are we?

Current Trends in Nanoeducation for Industry and Society

Cytokine antagonists and allergy

Dendritic cells activated by IFN-γ/STAT1 express IL-31 receptor and release proinflammatory mediators upon IL-31 treatment.

Determination of nitration degrees for the birch pollen allergen Bet v 1

Development of an on-line exposure system to determine freshly produced diesel engine emission-induced cellular effects.

Differential pro-inflammatory effects of metal oxide nanoparticles and their soluble ions in vitro and in vivo; zinc and copper nanoparticles, but not their ions, recruit eosinophils to the lungs

Dispersion medium modulates oxidative stress response of human lung epithelial cells upon exposure to carbon nanomaterial samples.

Early hematological and immunological alterations in gasoline station attendants exposed to benzene

Enhanced Deposition by Electrostatic Field-Assistance Aggravating Diesel Exhaust Aerosol Toxicity for Human Lung Cells.

Enzyme adsorption-induced activity changes: a quantitative study on TiO2 model agglomerates.

Functional reconstitution of halorhodopsin. Properties of halorhodopsin-containing proteoliposomes

Hardening of the nanoparticle-protein corona in metal (Au, Ag) and oxide (Fe3O4, CoO, and CeO2) nanoparticles.

Human Th2 but not Th9 cells release IL-31 in a STAT6/NF-κB-dependent way.

IL-1β induces expression of costimulatory molecules and cytokines but not immune feedback regulators in dendritic cells

IL-4 and IL-13 induce SOCS-1 gene expression in A549 cells by three functional STAT6-binding motifs located upstream of the transcription initiation site

IL-4 induces expression of TARC/CCL17 via two STAT6 binding sites

IL-4 receptor complexes containing or lacking the gamma C chain are inhibited by an overlapping set of antagonistic IL-4 mutant proteins

Identification of a distal tandem STAT6 element within the CCL17 locus

Immune Effects of the Nitrated Food Allergen Beta-Lactoglobulin in an Experimental Food Allergy Model

Impact of nanosilver on various DNA lesions and HPRT gene mutations - effects of charge and surface coating

In vitro investigation of immunomodulatory effects caused by engineered inorganic nanoparticles – the impact of experimental design and cell choice

Inhibiting the IL-4 receptor: why, how, and for whom?

Inhibition of suppressive T cell factor 1 (TCF-1) isoforms in naive CD4+ T cells is mediated by IL-4/STAT6 signaling

Inhibition of the IL-4/IL-13 receptor system prevents allergic sensitization without affecting established allergy in a mouse model for allergic asthma

Interaction of differently functionalized fluorescent silica nanoparticles with neural stem- and tissue-type cells

Interaction of nanoparticles with proteins: relation to bio-reactivity of the nanoparticle.

Interactions between effects of environmental chemicals and natural stressors: a review

Interactions of TiO2 Nanoparticles with Ingredients from Modern Lifestyle Products and Their Effects on Human Skin Cells

Interconversions of the M, N, and O intermediates in the bacteriorhodopsin photocycle.

Interleukin-13 selectively induces monocyte chemoattractant protein-1 synthesis and secretion by human endothelial cells. Involvement of IL-4R alpha and Stat6 phosphorylation

Interleukin-4 upregulates the heat shock protein Hsp90alpha and enhances transcription of a reporter gene coupled to a single heat shock element

Is the toxic potential of nanosilver dependent on its size?

JAK/STAT-dependent gene regulation by cytokines.

LEF-1 negatively controls interleukin-4 expression through a proximal promoter regulatory element

MUTZ-3, a monocytic model cell line for interleukin-4 and lipopolysaccharide studies

Mechanistic insights into silica nanoparticle–allergen interactions on antigen presenting cell function in the context of allergic reactions

Mouse macrophage development in the absence of the common γ chain: defining receptor complexes responsible for IL-4 and IL-13 signaling

NOD1 modulates IL-10 signalling in human dendritic cells

Nano-immunosafety: issues in assay validation

Nanomaterials in the Context of Type 2 Immune Responses-Fears and Potentials.

Nanoparticle-allergen interactions mediate human allergic responses: protein corona characterization and cellular responses.

Nanoparticles and innate immunity: new perspectives on host defence

Nanotechnology-Based Vaccines for Allergen-Specific Immunotherapy: Potentials and Challenges of Conventional and Novel Adjuvants under Research

Nitrated food proteins induce a regulatory immune response associated with allergy prevention after oral exposure in a Balb/c mouse food allergy model

Nitration enhances the allergenic potential of proteins.

Nitration of ovalbumin decreases the risk for sensitization via the oral route in a mouse food allergy model

Nitration of the birch pollen allergen Bet v 1.0101: efficiency and site-selectivity of liquid and gaseous nitrating agents.

Nitration of the egg-allergen ovalbumin enhances protein allergenicity but reduces the risk for oral sensitization in a murine model of food allergy.

Nitration of the pollen allergen bet v 1.0101 enhances the presentation of bet v 1-derived peptides by HLA-DR on human dendritic cells

Nitration of β-Lactoglobulin but Not of Ovomucoid Enhances Anaphylactic Responses in Food Allergic Mice.

Pan-European inter-laboratory studies on a panel of in vitro cytotoxicity and pro-inflammation assays for nanoparticles.

Particle toxicology and health - where are we?

Patulin influences the expression of Th1/Th2 cytokines by activated peripheral blood mononuclear cells and T cells through depletion of intracellular glutathione