Lista de obras - Benjamin Werner - Dominio Público Uruguay

A deterministic model for the occurrence and dynamics of multiple mutations in hierarchically organized tissues

artículo científico publicado en 2013

A somatic genetic clock for clonal species

artículo científico publicado en 2024

Author Correction: Quantification of subclonal selection in cancer from bulk sequencing data

scientific article published on 01 September 2018

Detecting truly clonal alterations from multi-region profiling of tumours

artículo científico publicado en 2017

Dynamical trade-offs arise from antagonistic coevolution and decrease intraspecific diversity.

artículo científico publicado en 2017

Dynamics of mutant cells in hierarchical organized tissues

artículo científico publicado en 2011

Dynamics of resistance development to imatinib under increasing selection pressure: a combination of mathematical models and in vitro data

artículo científico publicado en 2011

Evolutionary dynamics of neoantigens in growing tumors

artículo científico publicado en 2020

Evolutionary dynamics of neoantigens in growing tumours

Exploiting evolutionary steering to induce collateral drug sensitivity in cancer

scientific article published on 21 April 2020

Functional versus non-functional intratumor heterogeneity in cancer.

artículo científico publicado en 2016

Identification of neutral tumor evolution across cancer types.

artículo científico publicado en 2016

Measuring single cell divisions in human tissues from multi-region sequencing data

artículo científico publicado en 2020

Measuring the distribution of fitness effects in somatic evolution by combining clonal dynamics with dN/dS ratios

artículo científico publicado en 2020

Ontogenic growth as the root of fundamental differences between childhood and adult cancer

artículo científico publicado en 2015

Phenotypic plasticity and genetic control in colorectal cancer evolution

artículo científico publicado en 2022

Precise age estimation in clonal species using a somatic genetic clock

artículo científico publicado en 2023

Quantification of subclonal selection in cancer from bulk sequencing data

artículo científico publicado en 2018

Reconstructing the in vivo dynamics of hematopoietic stem cells from telomere length distributions

artículo científico publicado en 2015

Replicative cellular age distributions in compartmentalized tissues

scholarly article by Marvin A Böttcher et al published August 2018 in Journal of the Royal Society Interface

Reply to 'Currently available bulk sequencing data do not necessarily support a model of neutral tumor evolution'

article by Benjamin Werner et al published 29 October 2018 in Nature Genetics

Reply to ‘Revisiting signatures of neutral tumor evolution in the light of complexity of cancer genomic data’

scientific article published on 01 December 2018

Reply: Neutral tumor evolution?

Reply: Uncertainties in tumor allele frequencies limit power to infer evolutionary pressures

artículo científico publicado en 2017

Response to the Editor: On the Growth of Hematopoietic Stem Cells and Childhood Leukemias

artículo científico publicado en 2016

Self-tolerance in a minimal model of the idiotypic network.

artículo científico

Should tissue structure suppress or amplify selection to minimize cancer risk?

artículo científico publicado en 2016

Subclonal reconstruction of tumors by using machine learning and population genetics

scientific article published on 02 September 2020

The Cancer Stem Cell Fraction in Hierarchically Organized Tumors Can Be Estimated Using Mathematical Modeling and Patient-Specific Treatment Trajectories.

artículo científico publicado en 2016

The feedback between selection and demography shapes genomic diversity during coevolution

artículo científico publicado en 2019

The impact of random frequency-dependent mutations on the average population fitness ⬇️

artículo científico publicado el 30 de agosto de 2012

Variation of mutational burden in healthy human tissues suggests non-random strand segregation and allows measuring somatic mutation rates

artículo científico publicado en 2018

Lista de obras de Benjamin Werner

A deterministic model for the occurrence and dynamics of multiple mutations in hierarchically organized tissues

A somatic genetic clock for clonal species

Author Correction: Quantification of subclonal selection in cancer from bulk sequencing data

Detecting truly clonal alterations from multi-region profiling of tumours

Dynamical trade-offs arise from antagonistic coevolution and decrease intraspecific diversity.

Dynamics of mutant cells in hierarchical organized tissues

Dynamics of resistance development to imatinib under increasing selection pressure: a combination of mathematical models and in vitro data

Evolutionary dynamics of neoantigens in growing tumors

Evolutionary dynamics of neoantigens in growing tumours

Exploiting evolutionary steering to induce collateral drug sensitivity in cancer

Functional versus non-functional intratumor heterogeneity in cancer.

Identification of neutral tumor evolution across cancer types.

Measuring single cell divisions in human tissues from multi-region sequencing data

Measuring the distribution of fitness effects in somatic evolution by combining clonal dynamics with dN/dS ratios

Ontogenic growth as the root of fundamental differences between childhood and adult cancer

Phenotypic plasticity and genetic control in colorectal cancer evolution

Precise age estimation in clonal species using a somatic genetic clock

Quantification of subclonal selection in cancer from bulk sequencing data

Reconstructing the in vivo dynamics of hematopoietic stem cells from telomere length distributions

Replicative cellular age distributions in compartmentalized tissues

Reply to 'Currently available bulk sequencing data do not necessarily support a model of neutral tumor evolution'

Reply to ‘Revisiting signatures of neutral tumor evolution in the light of complexity of cancer genomic data’

Reply: Neutral tumor evolution?

Reply: Uncertainties in tumor allele frequencies limit power to infer evolutionary pressures

Response to the Editor: On the Growth of Hematopoietic Stem Cells and Childhood Leukemias

Self-tolerance in a minimal model of the idiotypic network.

Should tissue structure suppress or amplify selection to minimize cancer risk?

Subclonal reconstruction of tumors by using machine learning and population genetics

The Cancer Stem Cell Fraction in Hierarchically Organized Tumors Can Be Estimated Using Mathematical Modeling and Patient-Specific Treatment Trajectories.

The feedback between selection and demography shapes genomic diversity during coevolution

The impact of random frequency-dependent mutations on the average population fitness ⬇️

Variation of mutational burden in healthy human tissues suggests non-random strand segregation and allows measuring somatic mutation rates