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Lista de obras de Leng Han

A ROR1-HER3-lncRNA signalling axis modulates the Hippo-YAP pathway to regulate bone metastasis.

artículo científico publicado en 2017

Abnormal calcium handling properties underlie familial hypertrophic cardiomyopathy pathology in patient-specific induced pluripotent stem cells

artículo científico publicado en 2013

Advanced Datamining Using RNAseq Data

scholarly article

Advances in computational genomics

artículo científico publicado en 2015

Allele-Specific Reprogramming of Cancer Metabolism by the Long Non-coding RNA CCAT2

article

Allele-Specific Reprogramming of Cancer Metabolism by the Long Non-coding RNA CCAT2.

artículo científico publicado en 2016

Alternative applications for distinct RNA sequencing strategies

artículo científico publicado en 2014

An SVM-Based Algorithm for Classifying Promoter-Associated CpG Islands in the Human and Mouse Genomes

Assessing the clinical utility of cancer genomic and proteomic data across tumor types.

artículo científico publicado en 2014

Author Correction: Comprehensive molecular characterization of mitochondrial genomes in human cancers

artículo científico publicado en 2020

CSCD2: an integrated interactional database of cancer-specific circular RNAs

artículo científico publicado en 2022

Characterization of the dual functional effects of heat shock proteins (HSPs) in cancer hallmarks to aid development of HSP inhibitors

artículo científico publicado en 2020

Circular RNAs as promising biomarkers in cancer: detection, function, and beyond

artículo científico publicado en 2019

Comparative analysis of CpG islands in four fish genomes

artículo científico publicado en 2008

Comprehensive characterization of circular RNAs in ~ 1000 human cancer cell lines

artículo científico publicado en 2019

Comprehensive molecular characterization of mitochondrial genomes in human cancers

artículo científico publicado en 2020

Conservation and divergence of DNA methylation in eukaryotes: new insights from single base-resolution DNA methylomes

artículo científico publicado en 2011

Contrast features of CpG islands in the promoter and other regions in the dog genome

artículo científico publicado en 2009

CpG island density and its correlations with genomic features in mammalian genomes

artículo científico publicado en 2008

CpG islands or CpG clusters: how to identify functional GC-rich regions in a genome?

artículo científico publicado en 2009

CpG islands: algorithms and applications in methylation studies

artículo científico publicado en 2009

Dissecting the molecular relationship among various cardiogenic progenitor cells

artículo científico publicado en 2013

Early stem cell engraftment predicts late cardiac functional recovery: preclinical insights from molecular imaging

artículo científico publicado en 2012

Effective combinatorial immunotherapy for penile squamous cell carcinoma

artículo científico publicado en 2020

Efficient gene delivery of primary human cells using peptide linked polyethylenimine polymer hybrid

artículo científico publicado en 2011

Energy stress-induced lncRNA FILNC1 represses c-Myc-mediated energy metabolism and inhibits renal tumor development

artículo científico publicado en 2017

Erythrocytes retain hypoxic adenosine response for faster acclimatization upon re-ascent

artículo científico publicado en 2017

Escherichia coli Metabolite Profiling Leads to the Development of an RNA Interference Strain for Caenorhabditis elegans

scientific article published on 07 January 2020

Features and trend of loss of promoter-associated CpG islands in the human and mouse genomes

artículo científico publicado en 2007

Features of methylation and gene expression in the promoter-associated CpG islands using human methylome data

artículo científico publicado en 2012

Finding the lost treasures in exome sequencing data

artículo científico publicado en 2013

Gene co-expression network analysis reveals common system-level properties of prognostic genes across cancer types

artículo científico publicado en 2014

Gene- and evidence-based candidate gene selection for schizophrenia and gene feature analysis

artículo científico publicado en 2009

Genome-Wide DNA Methylation Profiling in 40 Breast Cancer Cell Lines

Global analysis of tRNA and translation factor expression reveals a dynamic landscape of translational regulation in human cancers

artículo científico publicado en 2018

INO80 facilitates pluripotency gene activation in embryonic stem cell self-renewal, reprogramming, and blastocyst development

artículo científico publicado en 2014

INO80 governs superenhancer-mediated oncogenic transcription and tumor growth in melanoma

artículo científico publicado en 2016

Integrated genomic analysis of recurrence-associated small non-coding RNAs in oesophageal cancer

artículo científico publicado en 2016

LNCediting: a database for functional effects of RNA editing in lncRNAs

scientific article published on 19 September 2016

LncRNA NBR2 engages a metabolic checkpoint by regulating AMPK under energy stress

artículo científico publicado en 2016

Methylation of promoters of microRNAs and their host genes in myelodysplastic syndromes.

artículo científico publicado en 2013

MicroRNA-302 increases reprogramming efficiency via repression of NR2F2.

artículo científico publicado en 2013

Microfluidic single-cell analysis shows that porcine induced pluripotent stem cell-derived endothelial cells improve myocardial function by paracrine activation

artículo científico publicado en 2012

Mining diverse small RNA species in the deep transcriptome

artículo científico publicado en 2014

Multi-omics prediction of immune-related adverse events during checkpoint immunotherapy

scientific article published on 02 October 2020

Nobiletin fortifies mitochondrial respiration in skeletal muscle to promote healthy aging against metabolic challenge

scientific article published on 28 August 2019

Oncogenic lncRNA downregulates cancer cell antigen presentation and intrinsic tumor suppression

artículo científico publicado en 2019

Pathway and Network Analysis of Schizophrenia Candidate Genes under Meta-Analysis Linkage Peaks

article

Patient-specific induced pluripotent stem cells as a model for familial dilated cardiomyopathy.

artículo científico publicado en 2012

Preclinical derivation and imaging of autologously transplanted canine induced pluripotent stem cells

artículo científico

Publisher Correction: Comprehensive molecular characterization of mitochondrial genomes in human cancers

artículo científico publicado en 2020

Publisher Correction: Transcribed ultraconserved region 339 promotes carcinogenesis by modulating tumor suppressor microRNAs

artículo científico publicado en 2018

RNA editing derived epitopes function as cancer antigens to elicit immune responses

scientific article published in Nature Communications

Safe genetic modification of cardiac stem cells using a site-specific integration technique

artículo científico publicado en 2012

Schizophrenia Genes: Characteristics of Function and Protein Interaction Networks

article

Sex-associated molecular differences for cancer immunotherapy

artículo científico publicado en 2020

Single-cell analysis of murine fibroblasts identifies neonatal to adult switching that regulates cardiomyocyte maturation

scientific article published on 22 May 2020

Single-cell and spatial analysis reveal interaction of FAP<sup>+</sup> fibroblasts and SPP1<sup>+</sup> macrophages in colorectal cancer

artículo científico publicado en 2022

Single-cell reconstruction of differentiation trajectory reveals a critical role of ETS1 in human cardiac lineage commitment

artículo científico publicado en 2019

Single-cell reconstruction of the adult human heart during heart failure and recovery reveals the cellular landscape underlying cardiac function

artículo científico publicado en 2020

Small-molecule MMP2/MMP9 inhibitor SB-3CT modulates tumor immune surveillance by regulating PD-L1

artículo científico publicado en 2020

Structural and Functional Insight of Sphingosine 1-Phosphate-Mediated Pathogenic Metabolic Reprogramming in Sickle Cell Disease

artículo científico publicado en 2017

Systematic prioritization and integrative analysis of copy number variations in schizophrenia reveal key schizophrenia susceptibility genes

artículo científico publicado en 2014

TANRIC: An Interactive Open Platform to Explore the Function of lncRNAs in Cancer

artículo científico publicado en 2015

TRIM59 promotes breast cancer motility by suppressing p62-selective autophagic degradation of PDCD10

artículo científico publicado en 2018

Targeting Glucose Metabolism Sensitizes Pancreatic Cancer to MEK Inhibition

artículo científico publicado en 2021

The Genomic Landscape and Clinical Relevance of A-to-I RNA Editing in Human Cancers

artículo científico publicado en 2015

The LINK-A lncRNA activates normoxic HIF1α signalling in triple-negative breast cancer

scientific journal article

The LINK-A lncRNA interacts with PtdIns(3,4,5)P3 to hyperactivate AKT and confer resistance to AKT inhibitors

artículo científico publicado en 2017

The Pan-Cancer analysis of pseudogene expression reveals biologically and clinically relevant tumour subtypes

artículo científico publicado en 2014

The THO complex regulates pluripotency gene mRNA export and controls embryonic stem cell self-renewal and somatic cell reprogramming

scientific journal article

The genetic and pharmacogenomic landscape of snoRNAs in human cancer

artículo científico publicado en 2020

The lncRNA H19 alleviates muscular dystrophy by stabilizing dystrophin

artículo científico publicado en 2020

Transcribed ultraconserved region 339 promotes carcinogenesis by modulating tumor suppressor microRNAs.

artículo científico publicado en 2017

Transcriptional landscape and clinical utility of enhancer RNAs for eRNA-targeted therapy in cancer

scientific article published on 08 October 2019

Variable activation of the DNA damage response pathways in patients undergoing single-photon emission computed tomography myocardial perfusion imaging

artículo científico publicado en 2015

p53-dependent autophagic degradation of TET2 modulates cancer therapeutic resistance

artículo científico publicado en 2018