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Lista de obras de Antonio Costanzo

A feedback regulatory loop between p63 and Dlx3: implications for epidermal differentiation.

artículo científico publicado en 2009

A myogenic differentiation checkpoint activated by genotoxic stress

artículo científico publicado en 2002

A p38-dependent pathway regulates DeltaNp63 DNA binding to p53-dependent promoters in UV-induced apoptosis of keratinocytes.

artículo científico publicado en 2005

A regulatory feedback loop involving p63 and IRF6 links the pathogenesis of 2 genetically different human ectodermal dysplasias

artículo científico publicado en 2010

A role of p73 in mitotic exit.

artículo científico publicado en 2005

A symphony of regulations centered on p63 to control development of ectoderm-derived structures

scientific article published on 22 May 2011

Actinic keratosis treated with an immune response modifier: a case report of six patients

artículo científico publicado en 2003

Activation of SAPK/JNK by TNF receptor 1 through a noncytotoxic TRAF2-dependent pathway

artículo científico publicado en 1997

Adalimumab for severe psoriasis and psoriatic arthritis: an open-label study in 30 patients previously treated with other biologics

artículo científico publicado en 2007

Adalimumab for the treatment of severe psoriasis and psoriatic arthritis

Additional complexity in p73: induction by mitogens in lymphoid cells and identification of two new splicing variants ε and ζ

scientific article published on 01 May 1999

Adenosine deaminase, a key enzyme in DNA precursors control, is a new p73 target.

artículo científico publicado en 2003

Apoptotic, non-apoptotic, and anti-apoptotic pathways of tumor necrosis factor signalling

artículo científico publicado en 1998

Ascorbate up-regulates MLH1 (Mut L homologue-1) and p73: implications for the cellular response to DNA damage

artículo científico publicado en 2002

CD28 costimulation regulates FOXP3 in a RelA/NF-κB-dependent mechanism.

artículo científico publicado en 2011

CD28 delivers a unique signal leading to the selective recruitment of RelA and p52 NF-kappaB subunits on IL-8 and Bcl-xL gene promoters.

scholarly article

Characterization of a new cancer-associated mutant of p53 with a missense mutation (K351N) in the tetramerization domain.

artículo científico publicado en 2009

Characterization of the hepatitis B virus transactivators: a possible direct role of the virus in the development of hepatocellular carcinoma

artículo científico publicado en 1993

Claudin-1 is a p63 target gene with a crucial role in epithelial development

artículo científico publicado en 2008

Clinical similarity of biosimilar ABP 501 to adalimumab in the treatment of patients with moderate to severe plaque psoriasis: A randomized, double-blind, multicenter, phase III study.

artículo científico publicado en 2017

Clinical similarity of the biosimilar ABP 501 compared with adalimumab after single transition: long-term results from a randomized controlled, double-blind, 52-week, phase III trial in patients with moderate-to-severe plaque psoriasis

artículo científico publicado en 2017

Consecutive use of different biological therapies in the treatment of psoriasis

artículo científico publicado en 2007

Cross-talks in the p53 family: deltaNp63 is an anti-apoptotic target for deltaNp73alpha and p53 gain-of-function mutants

artículo científico publicado en 2006

Crosstalk between skin inflammation and adipose tissue-derived products: pathogenic evidence linking psoriasis to increased adiposity.

artículo científico publicado en 2016

Cytokine expression in circulating T lymphocytes from patients undergoing carotid endarterectomy

artículo científico publicado en 2003

Cytotoxic T lymphocyte response to a wild type hepatitis B virus epitope in patients chronically infected by variant viruses carrying substitutions within the epitope.

artículo científico publicado en 1994

DLX5, FGF8 and the Pin1 isomerase control ΔNp63α protein stability during limb development: a regulatory loop at the basis of the SHFM and EEC congenital malformations

artículo científico publicado en 2014

DN-p73 is activated after DNA damage in a p53-dependent manner to regulate p53-induced cell cycle arrest.

artículo científico publicado en 2002

DNA damage-dependent acetylation of p73 dictates the selective activation of apoptotic target genes.

artículo científico publicado en 2002

DNp73α protects myogenic cells from apoptosis

artículo científico publicado en 2006

DeltaNp63 knockdown mice: A mouse model for AEC syndrome

artículo científico publicado en 2009

Detection of adalimumab and anti-adalimumab levels by ELISA: clinical considerations.

artículo científico publicado en 2014

Detection of replicative intermediates of viral RNA in peripheral blood mononuclear cells from chronic hepatitis C virus carriers

artículo científico publicado en 1993

Developmental factor IRF6 exhibits tumor suppressor activity in squamous cell carcinomas

artículo científico publicado en 2011

Diagnosis and management of moderate to severe adult atopic dermatitis: a Consensus by the Italian Society of Dermatology and Venereology (SIDeMaST), the Italian Association of Hospital Dermatologists (ADOI), the Italian Society of Allergy, Asthma a

artículo científico publicado en 2017

Different applications of monochromatic excimer light in skin diseases

artículo científico publicado en 2009

Differential regulation of E2F1 apoptotic target genes in response to DNA damage.

artículo científico publicado en 2003

Disease-related and drug-induced skin manifestations in inflammatory bowel disease.

artículo científico publicado en 2017

Efalizumab

scientific article published on 10 January 2011

Effectiveness End Points in Real-World Studies on Biological Therapies in Psoriasis: Systematic Review with Focus on Drug Survival

scholarly article by Antonio Costanzo et al published 2018 in Dermatology

Effects of insulin on in vitro vascular cell adhesion molecule-1 expression and in vivo soluble VCAM-1 release

artículo científico publicado en 1999

Efficacy and safety of etanercept in psoriasis after switching from other treatments: an observational study

artículo científico publicado en 2009

Efficacy of Short-Term Cyclosporine Treatment to Control Psoriasis-Related Events during Efalizumab Therapy

Efficacy of efalizumab in psoriasis patients previously treated with tumour necrosis factor blockers.

artículo científico publicado en 2009

Efficacy of monochromatic excimer laser radiation (308 nm) in the treatment of early stage mycosis fungoides.

artículo científico publicado en 2004

Elevated serum levels of 90K/MAC-2 BP predict unresponsiveness to alpha-interferon therapy in chronic HCV hepatitis patients.

artículo científico publicado en 1996

Emerging treatments in the management of psoriasis: biological targeting with ustekinumab

artículo científico publicado en 2009

Endothelial activation by angiotensin II through NFkappaB and p38 pathways: Involvement of NFkappaB-inducible kinase (NIK), free oxygen radicals, and selective inhibition by aspirin

artículo científico publicado en 2003

Erratum: Corrigendum: The antimicrobial peptide LL37 is a T-cell autoantigen in psoriasis

artículo científico publicado en 2015

Etanercept for the treatment of severe childhood psoriasis

artículo científico publicado en 2006

Evidence of increased apoptosis and reduced proliferation in basal cell carcinomas treated with tazarotene.

artículo científico publicado en 2004

FGF8, c-Abl and p300 participate in a pathway that controls stability and function of the ΔNp63α protein.

artículo científico publicado en 2015

Fas/Apo1 mutations and autoimmune lymphoproliferative syndrome in a patient with type 2 autoimmune hepatitis

article by L Pensati et al published October 1997 in Gastroenterology

Foreword: Seminars in Research 2014 Joint Experiences in Rheumatology and Dermatology

artículo científico publicado en 2016

Functionalized gold nanoparticles for topical delivery of methotrexate for the possible treatment of psoriasis.

artículo científico publicado en 2016

Genetic variations in IL6 and IL12B decreasing the risk for psoriasis.

artículo científico publicado en 2013

HIPK2 phosphorylates ΔNp63α and promotes its degradation in response to DNA damage.

artículo científico publicado en 2011

HLA-C*06 and psoriasis: susceptibility, phenotype, course and response to treatment

scientific article published on 01 April 2018

HLA-C*06 and response to ustekinumab in Caucasian patients with psoriasis: Outcome and long-term follow-up.

artículo científico publicado en 2016

Herpes simplex virus disrupts NF-kappaB regulation by blocking its recruitment on the IkappaBalpha promoter and directing the factor on viral genes

artículo científico publicado en 2006

Homeobox gene Dlx3 is regulated by p63 during ectoderm development: relevance in the pathogenesis of ectodermal dysplasias.

artículo científico publicado en 2007

IKKalpha is a p63 transcriptional target involved in the pathogenesis of ectodermal dysplasias

artículo científico publicado en 2008

IL-21 in the pathogenesis and treatment of skin diseases

artículo científico publicado en 2010

IL-21 promotes skin recruitment of CD4(+) cells and drives IFN-γ-dependent epidermal hyperplasia

artículo científico publicado en 2011

IL12B (p40) Gene Polymorphisms Contribute to Ustekinumab Response Prediction in Psoriasis.

artículo científico publicado en 2015

Increased levels of IL-17 in tear fluid of moderate-to-severe psoriatic patients is reduced by adalimumab therapy

artículo científico publicado en 2015

Induction of neuronal differentiation by p73 in a neuroblastoma cell line

artículo científico publicado en 2000

Induction of the DNA-binding activity of c-jun/c-fos heterodimers by the hepatitis B virus transactivator pX

artículo científico

Infection of circulating and liver infiltrating T cells by hepatitis C virus of different subtypes.

artículo científico publicado en 1995

Infliximab in psoriasis and psoriatic arthritis.

artículo científico

Involvement of interleukin-21 in the epidermal hyperplasia of psoriasis

Italian guidelines on the systemic treatments of moderate-to-severe plaque psoriasis.

artículo científico publicado en 2017

Label-free and non-invasive discrimination of HaCaT and melanoma cells in a co-culture model by hyperspectral confocal reflectance microscopy

article

Living matter observations with a novel hyperspectral supercontinuum confocal microscope for VIS to near-IR reflectance spectroscopy

artículo científico publicado en 2013

Living with Chronic Spontaneous Urticaria in Italy: A Narrative Medicine Project to Improve the Pathway of Patient Care.

artículo científico publicado en 2016

Long-term safety of etanercept in psoriasis: Retrospective study focused on infections

artículo científico publicado en 2016

Long-term treatment of plaque psoriasis with efalizumab: an Italian experience

article

Long-term treatment with adalimumab in psoriatic arthritis: serum adalimumab concentration, immunogenicity and the link with clinical response

artículo científico publicado en 2016

Long-term ustekinumab treatment for refractory type I pityriasis rubra pilaris.

artículo científico publicado en 2013

MEK1 inhibition sensitizes primary acute myelogenous leukemia to arsenic trioxide-induced apoptosis.

artículo científico publicado en 2006

Measuring psoriatic disease in clinical practice. An expert opinion position paper.

artículo científico

Mitogen-activated kinase kinase kinase 1 regulates T cell receptor- and CD28-mediated signaling events which lead to NF-kappaB activation

artículo científico publicado en 2000

Multidisciplinary Management of Spondyloarthritis-Related Immune-Mediated Inflammatory Disease.

artículo científico publicado en 2018

Nail Assessment in Psoriasis and Psoriatic Arthritis (NAPPA): development and validation of a tool for assessment of nail psoriasis outcomes.

artículo científico publicado en 2014

Nuclear factor kB-independent cytoprotective pathways originating at tumor necrosis factor receptor-associated factor 2

scientific journal article

Optimization of systemic treatments for chronic plaque psoriasis. Recommendations for switching and transitioning

artículo científico publicado en 2013

PSORS2 Markers Are Not Associated with Psoriatic Arthritis in the Italian Population

article

Patient-relevant needs and treatment goals in nail psoriasis

artículo científico publicado en 2015

Patients with Moderate to Severe Plaque Psoriasis: One Year after the European Medicines Agency Recommendation of Efalizumab Suspension

scientific article published on 13 April 2011

Pharmacogenetics of psoriasis:HLA-Cw6but notLCE3B/3Cdeletion norTNFAIP3polymorphism predisposes to clinical response to interleukin 12/23 blocker ustekinumab

article

Physical interaction with human tumor-derived p53 mutants inhibits p63 activities.

artículo científico publicado en 2002

Prevalence and genomic variability of transfusion transmitted virus in Italian cryptogenic chronic liver disease and healthy blood donors.

artículo científico publicado en 2002

Professor Sergio Chimenti: 1949-2016.

artículo científico publicado en 2016

Programmed cell death in the skin.

artículo científico

Psoriasis, from pathogenesis to therapeutic strategies: IL-21 as a novel potential therapeutic target.

artículo científico publicado en 2012

Psoriasis: from pathogenesis to novel therapeutic approaches

artículo científico publicado el 1 de enero de 2011

Psoriatic arthritis and CARD15 gene polymorphisms: no evidence for association in the Italian population.

artículo científico publicado en 2004

Psychiatric comorbidity and suicidal ideation in psoriasis, melanoma and allergic disorders

artículo científico publicado en 2017

Regulation of Dlx5 and Dlx6 gene expression by p63 is involved in EEC and SHFM congenital limb defects

scientific journal article

RelA/NF-kappaB recruitment on the bax gene promoter antagonizes p73-dependent apoptosis in costimulated T cells.

artículo científico publicado en 2007

Resistance to Fas-mediated apoptosis in human hepatoma cells.

artículo científico publicado en 1995

Role of the HLA-C*06 allele in clinical response to ustekinumab: evidence from real life in a large cohort of European patients.

artículo científico publicado en 2017

S100A8/A9 in psoriatic plaques from patients with psoriatic arthritis

artículo científico publicado en 2016

Safety and efficacy study on etanercept in patients with plaque psoriasis

artículo científico publicado en 2005

Secukinumab shows high efficacy irrespective of HLA-Cw6 status in patients with moderate-to-severe plaque-type psoriasis: SUPREME study

artículo científico publicado en 2018

Sox2 is not required for melanomagenesis, melanoma growth and melanoma metastasis in vivo.

artículo científico publicado en 2017

Structure, function and regulation of p63 and p73.

artículo científico publicado en 1999

Suicide risk and psychiatric comorbidity in patients with psoriasis.

artículo científico publicado en 2016

Superficial and nodular basal cell carcinomas treated with an immune response modifier: a report of seven patients.

artículo científico publicado en 2003

Systemic Therapy of Primary Cutaneous B-cell Lymphoma, Marginal Zone Type, with Rituximab, a Chimeric Anti-CD20 Monoclonal Antibody

artículo científico publicado en 2001

TP63 and TP73 in cancer, an unresolved "family" puzzle of complexity, redundancy and hierarchy

artículo científico publicado en 2014

TRIM8 and p53: making the right decision

artículo científico publicado en 2012

Targeted therapy in nonmelanoma skin cancers.

artículo científico publicado en 2011

Targeting MEK/MAPK signal transduction module potentiates ATO-induced apoptosis in multiple myeloma cells through multiple signaling pathways.

artículo científico publicado en 2008

The antimicrobial peptide LL37 is a T-cell autoantigen in psoriasis

artículo científico publicado en 2014

The impact of methodological approaches for presenting long-term clinical data on estimates of efficacy in psoriasis illustrated by three-year treatment data on infliximab

artículo científico publicado en 2010

The mechanistic basis for psoriasis immunopathogenesis: translating genotype to phenotype. Report of a workshop, Venice, 2012.

artículo científico publicado en 2013

The p53 family protein p73 provides new insights into cancer chemosensitivity and targeting.

artículo científico publicado en 2009

The p53/p63/p73 family of transcription factors: overlapping and distinct functions.

artículo científico publicado en 2000

The p73 gene is an anti-tumoral target of the RARbeta/gamma-selective retinoid tazarotene.

artículo científico publicado en 2004

The tumor suppressor activity of IKKalpha in stratified epithelia is exerted in part via the TGF-beta antiproliferative pathway

artículo científico publicado en 2008

The tyrosine kinase c-Abl regulates p73 in apoptotic response to cisplatin-induced DNA damage

artículo científico publicado en 1999

Topical treatment of basal cell carcinoma with tazarotene: a clinicopathological study on a large series of cases

artículo científico publicado en 2004

Towards a targeted therapy for pyoderma gangrenosum

artículo científico publicado en 2015

Treasure or artifact: a decade of p63 research speaks for itself.

artículo científico publicado en 2010

Treatment of vitiligo with the 308 nm excimer laser.

artículo científico publicado en 2004

Treatment with arsenic trioxide (ATO) and MEK1 inhibitor activates the p73-p53AIP1 apoptotic pathway in leukemia cells.

artículo científico publicado en 2004

Trichostatin A up-regulates p73 and induces Bax-dependent apoptosis in cisplatin-resistant ovarian cancer cells

artículo científico publicado en 2008

Tumor necrosis factor (TNF) receptor 1 signaling downstream of TNF receptor-associated factor 2. Nuclear factor kappaB (NFkappaB)-inducing kinase requirement for activation of activating protein 1 and NFkappaB but not of c-Jun N-terminal kinase/stre

artículo científico publicado en 1997

Two new p73 splice variants, gamma and delta, with different transcriptional activity.

artículo científico publicado en 1998

Use of biological drugs in patients with psoriasis and psoriatic arthritis in Italy: Results from the PSONG survey

artículo científico publicado en 2017

Ustekinumab for treatment of plaque psoriasis in a patient with Down syndrome.

artículo científico publicado en 2012

Ustekinumab treatment of erythrodermic psoriasis occurring after physical stress: a report of two cases.

scientific article published on 26 September 2013

Vav cooperates with CD28 to induce NF-kappaB activation via a pathway involving Rac-1 and mitogen-activated kinase kinase 1.

artículo científico publicado en 2002

Vav-1 and the IKK alpha subunit of I kappa B kinase functionally associate to induce NF-kappa B activation in response to CD28 engagement.

artículo científico publicado en 2003

What happened after the clinical trials: long-term safety and efficacy of ustekinumab in daily clinical practice.

artículo científico publicado en 2014

[Ashy dermatosis: clinico-pathological associations in two cases]

artículo científico publicado en 2008

deltaEF1 repressor controls selectively p53 family members during differentiation.

artículo científico publicado en 2005

p63 and p73 transactivate differentiation gene promoters in human keratinocytes

artículo científico publicado en 2000

p63 is an alternative p53 repressor in melanoma that confers chemoresistance and a poor prognosis.

artículo científico publicado en 2013

p63-dependent and independent mechanisms of nectin-1 and nectin-4 regulation in the epidermis

artículo científico publicado en 2015

p73 is regulated by phosphorylation at the G2/M transition.

artículo científico publicado en 2003