Lista de obras - Pernille Harris - Dominio Público Uruguay

(+)-Geodin fromAspergillus terreus

artículo científico publicado en 2011

A homozygous mutation in a consanguineous family consolidates the role of ALDH1A3 in autosomal recessive microphthalmia.

artículo científico publicado en 2013

A pathogenic haplotype, common in Europeans, causes autosomal recessive albinism and uncovers missing heritability in OCA1

artículo científico publicado en 2019

A simple two step procedure for purification of the catalytic domain of chicken tryptophan hydroxylase 1 in a form suitable for crystallization

artículo científico publicado en 2007

A stepwise optimization of crystals of rhamnogalacturonan lyase from Aspergillus aculeatus.

artículo científico publicado en 2002

Advancing Therapeutic Protein Discovery and Development through Comprehensive Computational and Biophysical Characterization

scientific article published on 07 January 2020

Allosteric regulation and communication between subunits in uracil phosphoribosyltransferase from Sulfolobus solfataricus

artículo científico publicado en 2005

Analysis of an industrial production suspension of Bacillus lentus subtilisin crystals by powder diffraction: a powerful quality-control tool

artículo científico publicado en 2014

Application of interpretable artificial neural networks to early monoclonal antibodies development

scientific article published on 18 May 2019

CYP1B1 Mutations in Individuals With Primary Congenital Glaucoma and Residing in Denmark.

artículo científico publicado en 2016

Characterization of Native Reversible Self-Association of a Monoclonal Antibody Mediated by Fab-Fab Interaction

artículo científico publicado en 2019

Cis-trans amide bond rotamers in β-peptoids and peptoids: evaluation of stereoelectronic effects in backbone and side chains.

artículo científico publicado en 2013

Concentrated protein solutions investigated using acoustic levitation and small-angle X-ray scattering

artículo científico publicado en 2020

Concerted bifunctionality of the dCTP deaminase-dUTPase from Methanocaldococcus jannaschii: A structural and pre-steady state kinetic analysis

artículo científico publicado en 2009

Conformational Stability Study of a Therapeutic Peptide Plectasin Using Molecular Dynamics Simulations in Combination with NMR

scientific article published on 31 May 2019

Crystal structure of tryptophan hydroxylase with bound amino acid substrate

artículo científico publicado en 2008

Crystal structure, vibrational spectroscopy and ab initio density functional theory calculations on the ionic liquid forming 1,1,3,3-tetramethylguanidinium bis{(trifluoromethyl)sulfonyl}amide.

artículo científico publicado en 2009

Crystal structures of the all-cysteinyl-coordinated D14C variant of Pyrococcus furiosus ferredoxin: [4Fe-4S] ↔ [3Fe-4S] cluster conversion

artículo científico publicado en 2011

Crystallization and preliminary X-ray analysis of maltose O-acetyltransferase

artículo científico publicado en 2001

Crystallization of [Fe3S4]-ferredoxin from the hyperthermophile archaeon Pyrococcus furiosus

artículo científico publicado en 2003

Effects of thionation and fluorination on cis-trans isomerization in tertiary amides: an investigation of N-alkylglycine (peptoid) rotamers.

artículo científico publicado en 2015

Glucagon-like Peptide 1 Conjugated to Recombinant Human Serum Albumin Variants with Modified Neonatal Fc Receptor Binding Properties. Impact on Molecular Structure and Half-Life

artículo científico publicado en 2017

Insulin fibrillation: The influence and coordination of Zn2.

artículo científico publicado en 2017

Interaction between structurally different heteroexopolysaccharides and β-lactoglobulin studied by solution scattering and analytical ultracentrifugation

artículo científico publicado en 2018

Investigations of Albumin-Insulin Detemir Complexes Using Molecular Dynamics Simulations and Free Energy Calculations

scientific article published on 16 December 2019

Isoform-Specific Substrate Inhibition Mechanism of Human Tryptophan Hydroxylase

artículo científico publicado en 2017

Mechanism of dTTP inhibition of the bifunctional dCTP deaminase:dUTPase encoded by Mycobacterium tuberculosis

artículo científico publicado en 2008

Methyl effect in azumamides provides insight into histone deacetylase inhibition by macrocycles

artículo científico publicado en 2014

Migratory Insertion of Hydrogen Isocyanide in the Pentacyano(methyl)cobaltate(III) Anion

artículo científico publicado en 2003

Mutational Analysis of Divalent Metal Ion Binding in the Active Site of Class II α-Mannosidase from Sulfolobus solfataricus

artículo científico publicado en 2015

NMR Spectroscopic Characterization of Methylcobalt(III) Compounds with Classical Ligands. Crystal Structures of [Co(NH3)5(CH3)]S2O6,trans-[Co(en)2(NH3)(CH3)]S2O6(en = 1,2-Ethanediamine), and [Co(NH3)6]-mer,trans-[Co(NO2)3(NH3)2(CH3)]2-trans- [Co(NO2)

artículo científico publicado en 1997

NMR spectroscopic and X-ray crystallographic study of methylcobalt(III) compounds with saturated amine ligands

artículo científico publicado en 2004

Novofumigatonin, a new orthoester meroterpenoid from Aspergillus novofumigatus

artículo científico publicado en 2008

Oligomerization of a Glucagon-like Peptide 1 Analog: Bridging Experiment and Simulations

artículo científico publicado en 2015

Polycyclic alkaloids via transannular Mannich reactions

artículo científico publicado en 2009

Reaction kinetics of acetone peroxide formation and structure investigations using Raman spectroscopy and X-ray diffraction.

artículo científico publicado en 2009

Remote Loading of (64)Cu(2+) into Liposomes without the Use of Ion Transport Enhancers

artículo científico publicado en 2015

Revealing the Dimeric Crystal and Solution Structure of β-Lactoglobulin at pH 4 and Its pH and Salt Dependent Monomer–Dimer Equilibrium

artículo científico publicado en 2018

Selenomethionine substitution of orotidine-5'-monophosphate decarboxylase causes a change in crystal contacts and space group

artículo científico publicado en 2001

Self-Interaction of Human Serum Albumin: A Formulation Perspective

artículo científico publicado en 2018

Self-Interactions of Two Monoclonal Antibodies: Small-Angle X-ray Scattering, Light Scattering, and Coarse-Grained Modeling

Small angle X-ray scattering and molecular dynamic simulations provide molecular insight for stability of recombinant human transferrin

artículo científico publicado en 2019

Small-angle neutron-scattering studies of the magnetic phase diagram of MnSi

Solution structures of long-acting insulin analogues and their complexes with albumin

scientific article published on 26 February 2019

Stabilization of tryptophan hydroxylase 2 by l-phenylalanine-induced dimerization.

artículo científico publicado en 2016

Structural basis for the catalytic mechanism of a proficient enzyme: orotidine 5'-monophosphate decarboxylase

artículo científico publicado en 2000

Structural characterization of 1,1,3,3-tetramethylguanidinium chloride ionic liquid by reversible SO2 gas absorption.

artículo científico publicado en 2013

Structural study of four complexes of theM-N2S2type derived from diethylphenylazothioformamide and the metals palladium, platinum, copper and nickel

artículo científico publicado en 2007

Structure of Bacillus halmapalus alpha-amylase crystallized with and without the substrate analogue acarbose and maltose.

artículo científico publicado en 2006

Structure of plastocyanin from the cyanobacterium Anabaena variabilis.

artículo científico publicado en 2006

Structure of the dimeric form of CTP synthase from Sulfolobus solfataricus

artículo científico publicado en 2011

Structure-based discovery of a new protein-aggregation breaking excipient

artículo científico publicado en 2019

Substrate binding induces domain movements in orotidine 5'-monophosphate decarboxylase

artículo científico publicado en 2002

Synthesis and characterization of mixed chalcogen triangular complexes with new Mo3(mu3-S)(mu2-Se2)3(4+) and M3(mu3-S)(mu2-Se)3(4+) (M = Mo, W) cluster cores

artículo científico publicado en 2009

The 1.5 A resolution crystal structure of [Fe3S4]-ferredoxin from the hyperthermophilic archaeon Pyrococcus furiosus.

artículo científico publicado en 2004

The CoIII-C bond in (1-thia-4,7-diazacyclodecyl-kappa3N4,N7,C10)(1,4,7-triazacyclononane-kappa3N1,N4,N7)cobalt(III) dithionate hydrate

artículo científico publicado en 2003

The crystal structure of human dopamine β-hydroxylase at 2.9 Å resolution

scientific journal article

The effect of point mutations on the biophysical properties of an anti-microbial peptide: development of a screening protocol for peptide stability screening

artículo científico publicado en 2020

The structure of Lactococcus lactis thioredoxin reductase reveals molecular features of photo-oxidative damage

artículo científico publicado en 2017

The structures of T6, T3R3 and R6 bovine insulin: combining X-ray diffraction and absorption spectroscopy

artículo científico publicado en 2012

Total Synthesis and Full Histone Deacetylase Inhibitory Profiling of Azumamides A–E as Well as β2- epi-Azumamide E and β3-epi-Azumamide E

artículo científico publicado en 2013

Towards accurate structural characterization of metal centres in protein crystals: the structures of Ni and Cu T6bovine insulin derivatives

artículo científico publicado en 2014

Triangular prism-shaped β-peptoid helices as unique biomimetic scaffolds

artículo científico publicado en 2015

Use of 19 F Differential Labelling for the Simultaneous Detection and Monitoring of Three Individual Proteins in a Serum Environment

scientific article published on 04 April 2019

X-ray crystal structure, Raman spectroscopy, and Ab initio density functional theory calculations on 1,1,3,3-tetramethylguanidinium bromide

artículo científico publicado en 2010

Lista de obras de Pernille Harris

(+)-Geodin fromAspergillus terreus

A homozygous mutation in a consanguineous family consolidates the role of ALDH1A3 in autosomal recessive microphthalmia.

A pathogenic haplotype, common in Europeans, causes autosomal recessive albinism and uncovers missing heritability in OCA1

A simple two step procedure for purification of the catalytic domain of chicken tryptophan hydroxylase 1 in a form suitable for crystallization

A stepwise optimization of crystals of rhamnogalacturonan lyase from Aspergillus aculeatus.

Advancing Therapeutic Protein Discovery and Development through Comprehensive Computational and Biophysical Characterization

Allosteric regulation and communication between subunits in uracil phosphoribosyltransferase from Sulfolobus solfataricus

Analysis of an industrial production suspension of Bacillus lentus subtilisin crystals by powder diffraction: a powerful quality-control tool

Application of interpretable artificial neural networks to early monoclonal antibodies development

CYP1B1 Mutations in Individuals With Primary Congenital Glaucoma and Residing in Denmark.

Characterization of Native Reversible Self-Association of a Monoclonal Antibody Mediated by Fab-Fab Interaction

Cis-trans amide bond rotamers in β-peptoids and peptoids: evaluation of stereoelectronic effects in backbone and side chains.

Concentrated protein solutions investigated using acoustic levitation and small-angle X-ray scattering

Concerted bifunctionality of the dCTP deaminase-dUTPase from Methanocaldococcus jannaschii: A structural and pre-steady state kinetic analysis

Conformational Stability Study of a Therapeutic Peptide Plectasin Using Molecular Dynamics Simulations in Combination with NMR

Crystal structure of tryptophan hydroxylase with bound amino acid substrate

Crystal structure, vibrational spectroscopy and ab initio density functional theory calculations on the ionic liquid forming 1,1,3,3-tetramethylguanidinium bis{(trifluoromethyl)sulfonyl}amide.

Crystal structures of the all-cysteinyl-coordinated D14C variant of Pyrococcus furiosus ferredoxin: [4Fe-4S] ↔ [3Fe-4S] cluster conversion

Crystallization and preliminary X-ray analysis of maltose O-acetyltransferase

Crystallization of [Fe3S4]-ferredoxin from the hyperthermophile archaeon Pyrococcus furiosus

Effects of thionation and fluorination on cis-trans isomerization in tertiary amides: an investigation of N-alkylglycine (peptoid) rotamers.

Glucagon-like Peptide 1 Conjugated to Recombinant Human Serum Albumin Variants with Modified Neonatal Fc Receptor Binding Properties. Impact on Molecular Structure and Half-Life

Insulin fibrillation: The influence and coordination of Zn2.

Interaction between structurally different heteroexopolysaccharides and β-lactoglobulin studied by solution scattering and analytical ultracentrifugation

Investigations of Albumin-Insulin Detemir Complexes Using Molecular Dynamics Simulations and Free Energy Calculations

Isoform-Specific Substrate Inhibition Mechanism of Human Tryptophan Hydroxylase

Mechanism of dTTP inhibition of the bifunctional dCTP deaminase:dUTPase encoded by Mycobacterium tuberculosis

Methyl effect in azumamides provides insight into histone deacetylase inhibition by macrocycles

Migratory Insertion of Hydrogen Isocyanide in the Pentacyano(methyl)cobaltate(III) Anion

Mutational Analysis of Divalent Metal Ion Binding in the Active Site of Class II α-Mannosidase from Sulfolobus solfataricus

NMR Spectroscopic Characterization of Methylcobalt(III) Compounds with Classical Ligands. Crystal Structures of [Co(NH3)5(CH3)]S2O6,trans-[Co(en)2(NH3)(CH3)]S2O6(en = 1,2-Ethanediamine), and [Co(NH3)6]-mer,trans-[Co(NO2)3(NH3)2(CH3)]2-trans- [Co(NO2)

NMR spectroscopic and X-ray crystallographic study of methylcobalt(III) compounds with saturated amine ligands

Novofumigatonin, a new orthoester meroterpenoid from Aspergillus novofumigatus

Oligomerization of a Glucagon-like Peptide 1 Analog: Bridging Experiment and Simulations

Polycyclic alkaloids via transannular Mannich reactions

Reaction kinetics of acetone peroxide formation and structure investigations using Raman spectroscopy and X-ray diffraction.

Remote Loading of (64)Cu(2+) into Liposomes without the Use of Ion Transport Enhancers

Revealing the Dimeric Crystal and Solution Structure of β-Lactoglobulin at pH 4 and Its pH and Salt Dependent Monomer–Dimer Equilibrium

Selenomethionine substitution of orotidine-5'-monophosphate decarboxylase causes a change in crystal contacts and space group

Self-Interaction of Human Serum Albumin: A Formulation Perspective

Self-Interactions of Two Monoclonal Antibodies: Small-Angle X-ray Scattering, Light Scattering, and Coarse-Grained Modeling

Small angle X-ray scattering and molecular dynamic simulations provide molecular insight for stability of recombinant human transferrin

Small-angle neutron-scattering studies of the magnetic phase diagram of MnSi

Solution structures of long-acting insulin analogues and their complexes with albumin

Stabilization of tryptophan hydroxylase 2 by l-phenylalanine-induced dimerization.

Structural basis for the catalytic mechanism of a proficient enzyme: orotidine 5'-monophosphate decarboxylase

Structural characterization of 1,1,3,3-tetramethylguanidinium chloride ionic liquid by reversible SO2 gas absorption.

Structural study of four complexes of theM-N2S2type derived from diethylphenylazothioformamide and the metals palladium, platinum, copper and nickel

Structure of Bacillus halmapalus alpha-amylase crystallized with and without the substrate analogue acarbose and maltose.

Structure of plastocyanin from the cyanobacterium Anabaena variabilis.

Structure of the dimeric form of CTP synthase from Sulfolobus solfataricus

Structure-based discovery of a new protein-aggregation breaking excipient

Substrate binding induces domain movements in orotidine 5'-monophosphate decarboxylase

Synthesis and characterization of mixed chalcogen triangular complexes with new Mo3(mu3-S)(mu2-Se2)3(4+) and M3(mu3-S)(mu2-Se)3(4+) (M = Mo, W) cluster cores

The 1.5 A resolution crystal structure of [Fe3S4]-ferredoxin from the hyperthermophilic archaeon Pyrococcus furiosus.

The CoIII-C bond in (1-thia-4,7-diazacyclodecyl-kappa3N4,N7,C10)(1,4,7-triazacyclononane-kappa3N1,N4,N7)cobalt(III) dithionate hydrate

The crystal structure of human dopamine β-hydroxylase at 2.9 Å resolution

The effect of point mutations on the biophysical properties of an anti-microbial peptide: development of a screening protocol for peptide stability screening

The structure of Lactococcus lactis thioredoxin reductase reveals molecular features of photo-oxidative damage

The structures of T6, T3R3 and R6 bovine insulin: combining X-ray diffraction and absorption spectroscopy

Total Synthesis and Full Histone Deacetylase Inhibitory Profiling of Azumamides A–E as Well as β2- epi-Azumamide E and β3-epi-Azumamide E

Towards accurate structural characterization of metal centres in protein crystals: the structures of Ni and Cu T6bovine insulin derivatives

Triangular prism-shaped β-peptoid helices as unique biomimetic scaffolds

Use of 19 F Differential Labelling for the Simultaneous Detection and Monitoring of Three Individual Proteins in a Serum Environment

X-ray crystal structure, Raman spectroscopy, and Ab initio density functional theory calculations on 1,1,3,3-tetramethylguanidinium bromide