Lista de obras - Antoni Planas - Dominio Público Uruguay

A Native Ternary Complex Trapped in a Crystal Reveals the Catalytic Mechanism of a Retaining Glycosyltransferase

artículo científico publicado en 2015

A specific chromophoric substrate for activity assays of 1,3-1,4-beta-D-glucan 4-glucanohydrolases.

artículo científico publicado en 1996

A transitional hydrolase to glycosynthase mutant by Glu to Asp substitution at the catalytic nucleophile in a retaining glycosidase.

artículo científico publicado en 2014

Acceptor-dependent regioselectivity of glycosynthase reactions by Streptomyces E383A beta-glucosidase

artículo científico publicado en 2006

Active-site mapping of a Populus xyloglucan endo-transglycosylase with a library of xylogluco-oligosaccharides.

artículo científico publicado en 2008

An engineered E.coli strain for the production of glycoglycerolipids

artículo científico publicado en 2012

Artificial mixed-linked β-glucans produced by glycosynthase-catalyzed polymerization: tuning morphology and degree of polymerization

scientific article published on 30 December 2010

Bacterial 1,3-1,4-beta-glucanases: structure, function and protein engineering.

artículo científico publicado en 2000

Carbohydrate-binding module assisting glycosynthase-catalysed polymerizations.

artículo científico

Catalytic Itinerary in 1,3-1,4-β-Glucanase Unraveled by QM/MM Metadynamics. Charge Is Not Yet Fully Developed at the Oxocarbenium Ion-like Transition State

artículo científico publicado en 2011

Chemical rescue of alpha3-galactosyltransferase. Implications in the mechanism of retaining glycosyltransferases

artículo científico publicado en 2006

Chitin Deacetylases: Structures, Specificities, and Biotech Applications

scientific article published on 22 March 2018

Conformational analyses of the reaction coordinate of glycosidases

artículo científico publicado el 16 de septiembre de 2011

Crystal structure of Bacillus licheniformis 1,3-1,4-beta-D-glucan 4-glucanohydrolase at 1.8 A resolution

artículo científico publicado en 1995

Enzymatic and cell factory approaches to the production of human milk oligosaccharides

scientific article published on 29 March 2019

Enzymatic production of defined chitosan oligomers with a specific pattern of acetylation using a combination of chitin oligosaccharide deacetylases

artículo científico

Essential Mycoplasma Glycolipid Synthase Adheres to the Cell Membrane by Means of an Amphipathic Helix

scientific article published on 08 May 2019

Essential catalytic role of Glu134 in endo-beta-1,3-1,4-D-glucan 4-glucanohydrolase from B. licheniformis as determined by site-directed mutagenesis.

artículo científico publicado en 1992

Expeditious synthesis of a new hexasaccharide using transglycosylation reaction catalyzed by Bacillus (1-->3),(1-->4)-Beta-D-glucan 4-glucanohydrolase

scientific article published on 01 September 1998

Expression and characterization of a Mycoplasma genitalium glycosyltransferase in membrane glycolipid biosynthesis: potential target against mycoplasma infections

artículo científico publicado en 2011

Expression and specificity of a chitin deacetylase from the nematophagous fungus Pochonia chlamydosporia potentially involved in pathogenicity

artículo científico publicado en 2018

Formation of a covalent glycosyl-enzyme species in a retaining glycosyltransferase

artículo científico publicado en 2013

Gene ontology function prediction in mollicutes using protein-protein association networks

artículo científico publicado en 2011

Glycosynthase activity of Bacillus licheniformis 1,3-1,4-beta-glucanase mutants: specificity, kinetics, and mechanism.

artículo científico publicado en 2003

Glycosynthase-type GH18 mutant chitinases at the assisting catalytic residue for polymerization of chitooligosaccharides

artículo científico publicado en 2019

How family 26 glycoside hydrolases orchestrate catalysis on different polysaccharides: structure and activity of a Clostridium thermocellum lichenase, CtLic26A.

artículo científico publicado en 2005

In vitro synthesis of a crystalline (1-->3,1-->4)-beta-D-glucan by a mutated (1-->3,1-->4)-beta-D-glucanase from Bacillus.

artículo científico publicado en 2004

In vitro synthesis of artificial polysaccharides by glycosidases and glycosynthases.

artículo científico publicado en 2007

Iodination of proteins by IPy2BF4, a new tool in protein chemistry.

artículo científico publicado en 2006

Iodine Atoms: A New Molecular Feature for the Design of Potent Transthyretin Fibrillogenesis Inhibitors

artículo científico publicado en 2009

Isatin derivatives, a novel class of transthyretin fibrillogenesis inhibitors

artículo científico publicado en 2009

Kinetic analysis using low-molecular mass xyloglucan oligosaccharides defines the catalytic mechanism of a Populus xyloglucan endotransglycosylase

artículo científico publicado en 2006

Kinetic assay for high-throughput screening of in vitro transthyretin amyloid fibrillogenesis inhibitors.

artículo científico publicado en 2005

Long-lived glycosyl-enzyme intermediate mimic produced by formate re-activation of a mutant endoglucanase lacking its catalytic nucleophile

artículo científico publicado en 2001

Mechanism of Bacillus 1,3-1,4-beta-D-glucan 4-glucanohydrolases: kinetics and pH studies with 4-methylumbelliferyl beta-D-glucan oligosaccharides.

artículo científico publicado en 1997

Mechanism of the family 1 beta-glucosidase from Streptomyces sp: catalytic residues and kinetic studies.

artículo científico publicado en 2001

Mechanism-based labeling defines the free energy change for formation of the covalent glycosyl-enzyme intermediate in a xyloglucan endo-transglycosylase

artículo científico publicado en 2008

Modulation of the fibrillogenesis inhibition properties of two transthyretin ligands by halogenation.

artículo científico publicado en 2013

Mutational analysis of the major loop of Bacillus 1,3-1,4-beta-D-glucan 4-glucanohydrolases. Effects on protein stability and substrate binding

artículo científico publicado en 1997

Oligosaccharide synthesis by coupled endo-glycosynthases of different specificity: a straightforward preparation of two mixed-linkage hexasaccharide substrates of 1,3/1,4-beta-glucanases

artículo científico publicado en 2001

Oxazoline or oxazolinium ion? the protonation state and conformation of the reaction intermediate of chitinase enzymes revisited

scientific article published on 29 November 2018

Prediction and Fourier transform infrared spectroscopy estimation of the secondary structure of a Bacillus licheniformis endo-beta-1,3-1,4-D-glucanase

artículo científico publicado el 30 de abril de 1992

Preparative Scale Production of Recombinant Human Transthyretin for Biophysical Studies of Protein-Ligand and Protein-Protein Interactions

artículo científico publicado en 2020

Probing the mechanism of Bacillus 1,3-1,4-beta-D-glucan 4-glucanohydrolases by chemical rescue of inactive mutants at catalytically essential residues

artículo científico publicado en 1998

Quantitative analysis of post-translational modifications in human serum transthyretin associated with familial amyloidotic polyneuropathy by targeted LC-MS and intact protein MS

scientific article published on 21 April 2015

Rapid monitoring of glycerol in fermentation growth media: Facilitating crude glycerol bioprocess development

artículo científico publicado en 2014

Rational design of a thermostable glycoside hydrolase from family 3 introduces β-glycosynthase activity

artículo científico publicado en 2016

Re-engineering specificity in 1,3-1, 4-β-glucanase to accept branched xyloglucan substrates

artículo científico publicado en 2011

Reengineering the catalytic lysine of aspartate aminotransferase by chemical elaboration of a genetically introduced cysteine

artículo científico publicado en 1991

Retrospective Mapping of SAR Data for TTR Protein in Chemico-Biological Space Using Ligand Efficiency Indices as a Guide to Drug Discovery Strategies.

artículo científico publicado en 2011

Screening Assay for Directed Evolution of Chitin Deacetylases: Application to Vibrio cholerae Deacetylase Mutant Libraries for Engineered Specificity

artículo científico publicado en 2018

Sequential protection-modification method for selective sulfhydryl group derivatization in proteins having more than one cysteine.

artículo científico publicado en 1990

Structural Snapshots and Loop Dynamics along the Catalytic Cycle of Glycosyltransferase GpgS.

artículo científico publicado en 2017

Structural basis for the substrate specificity of a Bacillus 1,3-1,4-beta-glucanase

artículo científico publicado en 2006

Structural basis of chitin oligosaccharide deacetylation

artículo científico publicado en 2014

Structural-Functional Analysis Reveals a Specific Domain Organization in Family GH20 Hexosaminidases

artículo científico publicado en 2015

Structure-function features of a Mycoplasma glycolipid synthase derived from structural data integration, molecular simulations, and mutational analysis

artículo científico publicado en 2013

Structure-function relationships underlying the dual N-acetylmuramic and N-acetylglucosamine specificities of the bacterial peptidoglycan deacetylase PdaC

artículo científico publicado en 2019

Substrate Recognition and Specificity of Chitin Deacetylases and Related Family 4 Carbohydrate Esterases.

artículo científico publicado en 2018

Substrate conformational changes in glycoside hydrolase catalysis. A first-principles molecular dynamics study

article

Substrate distortion in the Michaelis complex of Bacillus 1,3-1,4-beta-glucanase. Insight from first principles molecular dynamics simulations

artículo científico publicado en 2005

Synthesis of 4-methylumbelliferyl-beta-D-glucan oligosaccharides as specific chromophoric substrates of (1-->3), (1-->4)-beta-D-glucan 4-glucanohydrolases

artículo científico publicado en 1995

Synthesis of aryl 3-O-beta-cellobiosyl-beta-D-glucopyranosides for reactivity studies of 1,3-1,4-beta-glucanases

artículo científico publicado en 1998

The conformational free energy landscape of beta-D-glucopyranose. Implications for substrate preactivation in beta-glucoside hydrolases

artículo científico publicado en 2007

The conformational free-energy landscape of β-D-mannopyranose: evidence for a (1)S(5) → B(2,5) → (O)S(2) catalytic itinerary in β-mannosidases

artículo científico publicado en 2010

The crystal structure of the family 6 carbohydrate binding module from Cellvibrio mixtus endoglucanase 5a in complex with oligosaccharides reveals two distinct binding sites with different ligand specificities.

artículo científico

The family 11 carbohydrate-binding module of Clostridium thermocellum Lic26A-Cel5E accommodates beta-1,4- and beta-1,3-1,4-mixed linked glucans at a single binding site

artículo científico publicado en 2004

Thermal stabilization of an endoglucanase by cyclization

artículo científico publicado en 2012

Thermus thermophilus glycoside hydrolase family 57 branching enzyme: crystal structure, mechanism of action, and products formed

scientific journal article

Transthyretin aggregate-specific antibodies recognize cryptic epitopes on patient-derived amyloid fibrils.

artículo científico publicado en 2014

Tuning transthyretin amyloidosis inhibition properties of iododiflunisal by combinatorial engineering of the nonsalicylic ring substitutions.

artículo científico publicado en 2014

Lista de obras de Antoni Planas

A Native Ternary Complex Trapped in a Crystal Reveals the Catalytic Mechanism of a Retaining Glycosyltransferase

A specific chromophoric substrate for activity assays of 1,3-1,4-beta-D-glucan 4-glucanohydrolases.

A transitional hydrolase to glycosynthase mutant by Glu to Asp substitution at the catalytic nucleophile in a retaining glycosidase.

Acceptor-dependent regioselectivity of glycosynthase reactions by Streptomyces E383A beta-glucosidase

Active-site mapping of a Populus xyloglucan endo-transglycosylase with a library of xylogluco-oligosaccharides.

An engineered E.coli strain for the production of glycoglycerolipids

Artificial mixed-linked β-glucans produced by glycosynthase-catalyzed polymerization: tuning morphology and degree of polymerization

Bacterial 1,3-1,4-beta-glucanases: structure, function and protein engineering.

Carbohydrate-binding module assisting glycosynthase-catalysed polymerizations.

Catalytic Itinerary in 1,3-1,4-β-Glucanase Unraveled by QM/MM Metadynamics. Charge Is Not Yet Fully Developed at the Oxocarbenium Ion-like Transition State

Chemical rescue of alpha3-galactosyltransferase. Implications in the mechanism of retaining glycosyltransferases

Chitin Deacetylases: Structures, Specificities, and Biotech Applications

Conformational analyses of the reaction coordinate of glycosidases

Crystal structure of Bacillus licheniformis 1,3-1,4-beta-D-glucan 4-glucanohydrolase at 1.8 A resolution

Enzymatic and cell factory approaches to the production of human milk oligosaccharides

Enzymatic production of defined chitosan oligomers with a specific pattern of acetylation using a combination of chitin oligosaccharide deacetylases

Essential Mycoplasma Glycolipid Synthase Adheres to the Cell Membrane by Means of an Amphipathic Helix

Essential catalytic role of Glu134 in endo-beta-1,3-1,4-D-glucan 4-glucanohydrolase from B. licheniformis as determined by site-directed mutagenesis.

Expeditious synthesis of a new hexasaccharide using transglycosylation reaction catalyzed by Bacillus (1-->3),(1-->4)-Beta-D-glucan 4-glucanohydrolase

Expression and characterization of a Mycoplasma genitalium glycosyltransferase in membrane glycolipid biosynthesis: potential target against mycoplasma infections

Expression and specificity of a chitin deacetylase from the nematophagous fungus Pochonia chlamydosporia potentially involved in pathogenicity

Formation of a covalent glycosyl-enzyme species in a retaining glycosyltransferase

Gene ontology function prediction in mollicutes using protein-protein association networks

Glycosynthase activity of Bacillus licheniformis 1,3-1,4-beta-glucanase mutants: specificity, kinetics, and mechanism.

Glycosynthase-type GH18 mutant chitinases at the assisting catalytic residue for polymerization of chitooligosaccharides

How family 26 glycoside hydrolases orchestrate catalysis on different polysaccharides: structure and activity of a Clostridium thermocellum lichenase, CtLic26A.

In vitro synthesis of a crystalline (1-->3,1-->4)-beta-D-glucan by a mutated (1-->3,1-->4)-beta-D-glucanase from Bacillus.

In vitro synthesis of artificial polysaccharides by glycosidases and glycosynthases.

Iodination of proteins by IPy2BF4, a new tool in protein chemistry.

Iodine Atoms: A New Molecular Feature for the Design of Potent Transthyretin Fibrillogenesis Inhibitors

Isatin derivatives, a novel class of transthyretin fibrillogenesis inhibitors

Kinetic analysis using low-molecular mass xyloglucan oligosaccharides defines the catalytic mechanism of a Populus xyloglucan endotransglycosylase

Kinetic assay for high-throughput screening of in vitro transthyretin amyloid fibrillogenesis inhibitors.

Long-lived glycosyl-enzyme intermediate mimic produced by formate re-activation of a mutant endoglucanase lacking its catalytic nucleophile

Mechanism of Bacillus 1,3-1,4-beta-D-glucan 4-glucanohydrolases: kinetics and pH studies with 4-methylumbelliferyl beta-D-glucan oligosaccharides.

Mechanism of the family 1 beta-glucosidase from Streptomyces sp: catalytic residues and kinetic studies.

Mechanism-based labeling defines the free energy change for formation of the covalent glycosyl-enzyme intermediate in a xyloglucan endo-transglycosylase

Modulation of the fibrillogenesis inhibition properties of two transthyretin ligands by halogenation.

Mutational analysis of the major loop of Bacillus 1,3-1,4-beta-D-glucan 4-glucanohydrolases. Effects on protein stability and substrate binding

Oligosaccharide synthesis by coupled endo-glycosynthases of different specificity: a straightforward preparation of two mixed-linkage hexasaccharide substrates of 1,3/1,4-beta-glucanases

Oxazoline or oxazolinium ion? the protonation state and conformation of the reaction intermediate of chitinase enzymes revisited

Prediction and Fourier transform infrared spectroscopy estimation of the secondary structure of a Bacillus licheniformis endo-beta-1,3-1,4-D-glucanase

Preparative Scale Production of Recombinant Human Transthyretin for Biophysical Studies of Protein-Ligand and Protein-Protein Interactions

Probing the mechanism of Bacillus 1,3-1,4-beta-D-glucan 4-glucanohydrolases by chemical rescue of inactive mutants at catalytically essential residues

Quantitative analysis of post-translational modifications in human serum transthyretin associated with familial amyloidotic polyneuropathy by targeted LC-MS and intact protein MS

Rapid monitoring of glycerol in fermentation growth media: Facilitating crude glycerol bioprocess development

Rational design of a thermostable glycoside hydrolase from family 3 introduces β-glycosynthase activity

Re-engineering specificity in 1,3-1, 4-β-glucanase to accept branched xyloglucan substrates

Reengineering the catalytic lysine of aspartate aminotransferase by chemical elaboration of a genetically introduced cysteine

Retrospective Mapping of SAR Data for TTR Protein in Chemico-Biological Space Using Ligand Efficiency Indices as a Guide to Drug Discovery Strategies.

Screening Assay for Directed Evolution of Chitin Deacetylases: Application to Vibrio cholerae Deacetylase Mutant Libraries for Engineered Specificity

Sequential protection-modification method for selective sulfhydryl group derivatization in proteins having more than one cysteine.

Structural Snapshots and Loop Dynamics along the Catalytic Cycle of Glycosyltransferase GpgS.

Structural basis for the substrate specificity of a Bacillus 1,3-1,4-beta-glucanase

Structural basis of chitin oligosaccharide deacetylation

Structural-Functional Analysis Reveals a Specific Domain Organization in Family GH20 Hexosaminidases

Structure-function features of a Mycoplasma glycolipid synthase derived from structural data integration, molecular simulations, and mutational analysis

Structure-function relationships underlying the dual N-acetylmuramic and N-acetylglucosamine specificities of the bacterial peptidoglycan deacetylase PdaC

Substrate Recognition and Specificity of Chitin Deacetylases and Related Family 4 Carbohydrate Esterases.

Substrate conformational changes in glycoside hydrolase catalysis. A first-principles molecular dynamics study

Substrate distortion in the Michaelis complex of Bacillus 1,3-1,4-beta-glucanase. Insight from first principles molecular dynamics simulations

Synthesis of 4-methylumbelliferyl-beta-D-glucan oligosaccharides as specific chromophoric substrates of (1-->3), (1-->4)-beta-D-glucan 4-glucanohydrolases

Synthesis of aryl 3-O-beta-cellobiosyl-beta-D-glucopyranosides for reactivity studies of 1,3-1,4-beta-glucanases

The conformational free energy landscape of beta-D-glucopyranose. Implications for substrate preactivation in beta-glucoside hydrolases

The conformational free-energy landscape of β-D-mannopyranose: evidence for a (1)S(5) → B(2,5) → (O)S(2) catalytic itinerary in β-mannosidases

The crystal structure of the family 6 carbohydrate binding module from Cellvibrio mixtus endoglucanase 5a in complex with oligosaccharides reveals two distinct binding sites with different ligand specificities.

The family 11 carbohydrate-binding module of Clostridium thermocellum Lic26A-Cel5E accommodates beta-1,4- and beta-1,3-1,4-mixed linked glucans at a single binding site

Thermal stabilization of an endoglucanase by cyclization

Thermus thermophilus glycoside hydrolase family 57 branching enzyme: crystal structure, mechanism of action, and products formed

Transthyretin aggregate-specific antibodies recognize cryptic epitopes on patient-derived amyloid fibrils.

Tuning transthyretin amyloidosis inhibition properties of iododiflunisal by combinatorial engineering of the nonsalicylic ring substitutions.