Lista de obras - Wiep Klaas Smits - Dominio Público Uruguay

#EUROmicroMOOC: using Twitter to share trends in Microbiology worldwide

scientific article published on 01 June 2019

A helicase-containing module defines a family of pCD630-like plasmids in Clostridium difficile

artículo científico publicado en 2017

A single, specific thymine mutation in the ComK-binding site severely decreases binding and transcription activation by the competence transcription factor ComK of Bacillus subtilis.

artículo científico publicado en 2007

An in silico survey of Clostridioides difficile extrachromosomal elements

scientific article published in 2019

Bistability, epigenetics, and bet-hedging in bacteria

artículo científico publicado en 2008

C. difficile 630Δerm Spo0A regulates sporulation, but does not contribute to toxin production, by direct high-affinity binding to target DNA

artículo científico publicado en 2012

Characterization of the virulence of a non-RT027, non-RT078 and binary toxin-positive Clostridium difficile strain associated with severe diarrhea

artículo científico publicado en 2018

Chromosomal replication initiation machinery of low-G+C-content Firmicutes

artículo científico

Clostridioides difficile Phosphoproteomics Shows an Expansion of Phosphorylated Proteins in Stationary Growth Phase

artículo científico publicado en 2022

Clostridium difficile infection ⬇️

Complete genome sequence of BS49 and draft genome sequence of BS34A, Bacillus subtilis strains carrying Tn916

artículo científico publicado en 2015

Complete genome sequence of the Clostridium difficile laboratory strain 630Δerm reveals differences from strain 630, including translocation of the mobile element CTn5.

artículo científico publicado en 2015

Cyclodextrin/Adamantane-Mediated Targeting of Inoculated Bacteria in Mice

artículo científico publicado en 2021

DNA replication proteins as potential targets for antimicrobials in drug-resistant bacterial pathogens.

artículo científico publicado en 2017

Fluorescent imaging of bacterial infections and recent advances made with multimodal radiopharmaceuticals

Functional genomics reveals that Clostridium difficile Spo0A coordinates sporulation, virulence and metabolism

artículo científico publicado en 2014

Genome Location Dictates the Transcriptional Response to PolC Inhibition in Clostridium difficile

artículo científico publicado en 2019

Genome2D: a visualization tool for the rapid analysis of bacterial transcriptome data

artículo científico publicado en 2004

Haem is crucial for medium-dependent metronidazole resistance in clinical isolates of Clostridioides difficile

artículo científico publicado en 2021

Hype or hypervirulence: a reflection on problematic C. difficile strains.

artículo científico publicado en 2013

Identification of the Unwinding Region in the <i>Clostridioides difficile</i> Chromosomal Origin of Replication

artículo científico publicado en 2020

Improving the predictive value of the competence transcription factor (ComK) binding site in Bacillus subtilis using a genomic approach

artículo científico publicado en 2002

Interspecies Interactions between Clostridium difficile and Candida albicans

artículo científico publicado en 2016

Mechanistic Insights in the Success of Fecal Microbiota Transplants for the Treatment of Clostridium difficile Infections.

artículo científico publicado en 2018

Multimodal Tracking of Controlled Staphylococcus aureus Infections in Mice

scientific article published on 02 May 2019

Ordered association of helicase loader proteins with the Bacillus subtilis origin of replication in vivo

artículo científico publicado en 2009

Phenotypic variation in bacteria: the role of feedback regulation

artículo científico publicado en 2006

Plasmid-mediated metronidazole resistance in Clostridioides difficile

artículo científico publicado en 2020

Practical observations on the use of fluorescent reporter systems in Clostridioides difficile ⬇️

artículo científico

Primase is required for helicase activity and helicase alters the specificity of primase in the enteropathogen Clostridium difficile

artículo científico publicado en 2016

Primosomal proteins DnaD and DnaB are recruited to chromosomal regions bound by DnaA in Bacillus subtilis

artículo científico publicado en 2010

Production and secretion stress caused by overexpression of heterologous alpha-amylase leads to inhibition of sporulation and a prolonged motile phase in Bacillus subtilis

artículo científico

Proteomic identification of Axc, a novel beta-lactamase with carbapenemase activity in a meropenem-resistant clinical isolate of Achromobacter xylosoxidans

Proteomic identification of Axc, a novel beta-lactamase with carbapenemase activity in a meropenem-resistant clinical isolate of Achromobacter xylosoxidans.

artículo científico publicado en 2018

Redefining the Clostridioides difficile σB Regulon: σB Activates Genes Involved in Detoxifying Radicals That Can Result from the Exposure to Antimicrobials and Hydrogen Peroxide

scientific article published on 16 September 2020

SNP-ing out the differences: Investigating differences between Clostridium difficile lab strains

artículo científico publicado en 2016

Single cell analysis of gene expression patterns of competence development and initiation of sporulation in Bacillus subtilis grown on chemically defined media.

artículo científico publicado en 2006

Stripping Bacillus: ComK auto-stimulation is responsible for the bistable response in competence development

artículo científico publicado en 2005

TcdC does not significantly repress toxin expression in Clostridium difficile 630ΔErm

artículo científico publicado en 2012

Temporal separation of distinct differentiation pathways by a dual specificity Rap-Phr system in Bacillus subtilis

artículo científico publicado en 2007

The Bacterial Chromatin Protein HupA Can Remodel DNA and Associates with the Nucleoid in Clostridium difficile

artículo científico publicado en 2019

The HtrA-like protease CD3284 modulates virulence of Clostridium difficile

artículo científico publicado en 2014

The Signal Sequence of the Abundant Extracellular Metalloprotease PPEP-1 Can Be Used to Secrete Synthetic Reporter Proteins in Clostridium difficile.

artículo científico publicado en 2016

The evolving epidemic of Clostridium difficile 630

artículo científico publicado en 2018

The transcriptional regulator Rok binds A+T-rich DNA and is involved in repression of a mobile genetic element in Bacillus subtilis.

artículo científico publicado en 2010

Tricksy business: transcriptome analysis reveals the involvement of thioredoxin A in redox homeostasis, oxidative stress, sulfur metabolism, and cellular differentiation in Bacillus subtilis

artículo científico publicado en 2005

Ubiquitous late competence genes in Bacillus species indicate the presence of functional DNA uptake machineries.

artículo científico publicado en 2009

Untwisting of the DNA helix stimulates the endonuclease activity of Bacillus subtilis Nth at AP sites

artículo científico publicado en 2011

Visualization of differential gene expression by improved cyan fluorescent protein and yellow fluorescent protein production in Bacillus subtilis

artículo científico publicado en 2004

When simple sequence comparison fails: the cryptic case of the shared domains of the bacterial replication initiation proteins DnaB and DnaD.

artículo científico publicado en 2010

Lista de obras de Wiep Klaas Smits

#EUROmicroMOOC: using Twitter to share trends in Microbiology worldwide

A helicase-containing module defines a family of pCD630-like plasmids in Clostridium difficile

A single, specific thymine mutation in the ComK-binding site severely decreases binding and transcription activation by the competence transcription factor ComK of Bacillus subtilis.

An in silico survey of Clostridioides difficile extrachromosomal elements

Bistability, epigenetics, and bet-hedging in bacteria

C. difficile 630Δerm Spo0A regulates sporulation, but does not contribute to toxin production, by direct high-affinity binding to target DNA

Characterization of the virulence of a non-RT027, non-RT078 and binary toxin-positive Clostridium difficile strain associated with severe diarrhea

Chromosomal replication initiation machinery of low-G+C-content Firmicutes

Clostridioides difficile Phosphoproteomics Shows an Expansion of Phosphorylated Proteins in Stationary Growth Phase

Clostridium difficile infection ⬇️

Complete genome sequence of BS49 and draft genome sequence of BS34A, Bacillus subtilis strains carrying Tn916

Complete genome sequence of the Clostridium difficile laboratory strain 630Δerm reveals differences from strain 630, including translocation of the mobile element CTn5.

Cyclodextrin/Adamantane-Mediated Targeting of Inoculated Bacteria in Mice

DNA replication proteins as potential targets for antimicrobials in drug-resistant bacterial pathogens.

Fluorescent imaging of bacterial infections and recent advances made with multimodal radiopharmaceuticals

Functional genomics reveals that Clostridium difficile Spo0A coordinates sporulation, virulence and metabolism

Genome Location Dictates the Transcriptional Response to PolC Inhibition in Clostridium difficile

Genome2D: a visualization tool for the rapid analysis of bacterial transcriptome data

Haem is crucial for medium-dependent metronidazole resistance in clinical isolates of Clostridioides difficile

Hype or hypervirulence: a reflection on problematic C. difficile strains.

Identification of the Unwinding Region in the <i>Clostridioides difficile</i> Chromosomal Origin of Replication

Improving the predictive value of the competence transcription factor (ComK) binding site in Bacillus subtilis using a genomic approach

Interspecies Interactions between Clostridium difficile and Candida albicans

Mechanistic Insights in the Success of Fecal Microbiota Transplants for the Treatment of Clostridium difficile Infections.

Multimodal Tracking of Controlled Staphylococcus aureus Infections in Mice

Ordered association of helicase loader proteins with the Bacillus subtilis origin of replication in vivo

Phenotypic variation in bacteria: the role of feedback regulation

Plasmid-mediated metronidazole resistance in Clostridioides difficile

Practical observations on the use of fluorescent reporter systems in Clostridioides difficile ⬇️

Primase is required for helicase activity and helicase alters the specificity of primase in the enteropathogen Clostridium difficile

Primosomal proteins DnaD and DnaB are recruited to chromosomal regions bound by DnaA in Bacillus subtilis

Production and secretion stress caused by overexpression of heterologous alpha-amylase leads to inhibition of sporulation and a prolonged motile phase in Bacillus subtilis

Proteomic identification of Axc, a novel beta-lactamase with carbapenemase activity in a meropenem-resistant clinical isolate of Achromobacter xylosoxidans

Proteomic identification of Axc, a novel beta-lactamase with carbapenemase activity in a meropenem-resistant clinical isolate of Achromobacter xylosoxidans.

Redefining the Clostridioides difficile σB Regulon: σB Activates Genes Involved in Detoxifying Radicals That Can Result from the Exposure to Antimicrobials and Hydrogen Peroxide

SNP-ing out the differences: Investigating differences between Clostridium difficile lab strains

Single cell analysis of gene expression patterns of competence development and initiation of sporulation in Bacillus subtilis grown on chemically defined media.

Stripping Bacillus: ComK auto-stimulation is responsible for the bistable response in competence development

TcdC does not significantly repress toxin expression in Clostridium difficile 630ΔErm

Temporal separation of distinct differentiation pathways by a dual specificity Rap-Phr system in Bacillus subtilis

The Bacterial Chromatin Protein HupA Can Remodel DNA and Associates with the Nucleoid in Clostridium difficile

The HtrA-like protease CD3284 modulates virulence of Clostridium difficile

The Signal Sequence of the Abundant Extracellular Metalloprotease PPEP-1 Can Be Used to Secrete Synthetic Reporter Proteins in Clostridium difficile.

The evolving epidemic of Clostridium difficile 630

The transcriptional regulator Rok binds A+T-rich DNA and is involved in repression of a mobile genetic element in Bacillus subtilis.

Tricksy business: transcriptome analysis reveals the involvement of thioredoxin A in redox homeostasis, oxidative stress, sulfur metabolism, and cellular differentiation in Bacillus subtilis

Ubiquitous late competence genes in Bacillus species indicate the presence of functional DNA uptake machineries.

Untwisting of the DNA helix stimulates the endonuclease activity of Bacillus subtilis Nth at AP sites

Visualization of differential gene expression by improved cyan fluorescent protein and yellow fluorescent protein production in Bacillus subtilis

When simple sequence comparison fails: the cryptic case of the shared domains of the bacterial replication initiation proteins DnaB and DnaD.