Lista de obras - Albert Giralt - Dominio Público Uruguay

7,8-dihydroxyflavone ameliorates cognitive and motor deficits in a Huntington's disease mouse model through specific activation of the PLCγ1 pathway

artículo científico publicado en 2017

A role for Kalirin-7 in corticostriatal synaptic dysfunction in Huntington's disease

artículo científico publicado en 2015

Activation of Elk-1 participates as a neuroprotective compensatory mechanism in models of Huntington's disease

artículo científico publicado en 2012

Acute drug-induced spine changes in the nucleus accumbens are dependent on β-adducin.

artículo científico publicado en 2016

Age-dependent decline of motor neocortex but not hippocampal performance in heterozygous BDNF mice correlates with a decrease of cortical PSD-95 but an increase of hippocampal TrkB levels.

artículo científico publicado en 2012

Age-dependent maintenance of motor control and corticostriatal innervation by death receptor 3.

artículo científico publicado en 2010

Age-related changes in STriatal-Enriched protein tyrosine Phosphatase levels: Regulation by BDNF.

artículo científico publicado en 2017

Astrocytic BDNF and TrkB regulate severity and neuronal activity in mouse models of temporal lobe epilepsy

artículo científico publicado en 2020

BDNF regulation under GFAP promoter provides engineered astrocytes as a new approach for long-term protection in Huntington's disease.

artículo científico publicado en 2010

Brain-derived neurotrophic factor modulates the severity of cognitive alterations induced by mutant huntingtin: involvement of phospholipaseCgamma activity and glutamate receptor expression

artículo científico publicado en 2008

Caveolin-1 deficiency causes cholesterol-dependent mitochondrial dysfunction and apoptotic susceptibility.

artículo científico publicado en 2011

Cognitive Dysfunction in Huntington's Disease: Humans, Mouse Models and Molecular Mechanisms

artículo científico publicado en 2012

Conditional BDNF Delivery from Astrocytes Rescues Memory Deficits, Spine Density, and Synaptic Properties in the 5xFAD Mouse Model of Alzheimer Disease

scientific article published on 30 January 2019

Conditional BDNF release under pathological conditions improves Huntington's disease pathology by delaying neuronal dysfunction

artículo científico publicado en 2011

Cryostat Slice Irregularities May Introduce Bias in Tissue Thickness Estimation: Relevance for Cell Counting Methods.

artículo científico publicado en 2015

Cyclin-Dependent Kinase 5 Dysfunction Contributes to Depressive-like Behaviors in Huntington's Disease by Altering the DARPP-32 Phosphorylation Status in the Nucleus Accumbens

scientific article published on 13 March 2019

Cytotoxic effect of neuromyelitis optica antibody (NMO-IgG) to astrocytes: an in vitro study

artículo científico publicado en 2009

DARPP-32 interaction with adducin may mediate rapid environmental effects on striatal neurons

artículo científico publicado en 2015

Differential neuroprotective effects of 5'-deoxy-5'-methylthioadenosine

artículo científico publicado en 2014

Disease-specific phenotypes in dopamine neurons from human iPS-based models of genetic and sporadic Parkinson's disease.

artículo científico publicado en 2012

Disruption of striatal glutamatergic transmission induced by mutant huntingtin involves remodeling of both postsynaptic density and NMDA receptor signaling

artículo científico publicado en 2007

Dissociation between CA3-CA1 synaptic plasticity and associative learning in TgNTRK3 transgenic mice.

artículo científico publicado en 2007

Early Downregulation of p75NTR by Genetic and Pharmacological Approaches Delays the Onset of Motor Deficits and Striatal Dysfunction in Huntington's Disease Mice.

artículo científico publicado en 2018

Early L-dopa, but not pramipexole, restores basal ganglia activity in partially 6-OHDA-lesioned rats

artículo científico publicado en 2013

Fingolimod (FTY720) enhances hippocampal synaptic plasticity and memory in Huntington's disease by preventing p75NTR up-regulation and astrocyte-mediated inflammation.

artículo científico publicado en 2015

Helios expression coordinates the development of a subset of striatopallidal medium spiny neurons

artículo científico publicado en 2017

Helios modulates the maturation of a CA1 neuronal subpopulation required for spatial memory formation

artículo científico publicado en 2019

Imbalance of p75(NTR)/TrkB protein expression in Huntington's disease: implication for neuroprotective therapies.

artículo científico publicado en 2013

Increased PKA signaling disrupts recognition memory and spatial memory: role in Huntington's disease

artículo científico publicado en 2011

Long-term memory deficits in Huntington's disease are associated with reduced CBP histone acetylase activity.

artículo científico publicado en 2011

Loss of striatal 90-kDa ribosomal S6 kinase (Rsk) is a key factor for motor, synaptic and transcription dysfunction in Huntington's disease

artículo científico publicado en 2016

Neurobehavioral characterization of Endonuclease G knockout mice reveals a new putative molecular player in the regulation of anxiety

artículo científico publicado en 2013

Neurotrophin receptor p75(NTR) mediates Huntington's disease-associated synaptic and memory dysfunction

artículo científico publicado en 2014

PDE10 inhibition increases GluA1 and CREB phosphorylation and improves spatial and recognition memories in a Huntington's disease mouse model

artículo científico publicado en 2013

PH domain leucine-rich repeat protein phosphatase 1 contributes to maintain the activation of the PI3K/Akt pro-survival pathway in Huntington's disease striatum.

artículo científico publicado en 2009

PKR knockout in the 5xFAD model of Alzheimer's disease reveals beneficial effects on spatial memory and brain lesions.

artículo científico publicado en 2019

PTK2B/Pyk2 overexpression improves a mouse model of Alzheimer's disease.

artículo científico publicado en 2018

Prostaglandin E2 EP1 receptor antagonist improves motor deficits and rescues memory decline in R6/1 mouse model of Huntington's disease

artículo científico publicado en 2013

Prostaglandin E2 EP2 activation reduces memory decline in R6/1 mouse model of Huntington's disease by the induction of BDNF-dependent synaptic plasticity.

artículo científico publicado en 2015

Pyk2 in the amygdala modulates chronic stress sequelae via PSD-95-related micro-structural changes

artículo científico publicado en 2019

Pyk2 is essential for astrocytes mobility following brain lesion

artículo científico publicado en 2015

Pyk2 modulates hippocampal excitatory synapses and contributes to cognitive deficits in a Huntington's disease model

artículo científico publicado en 2017

Reduced calcineurin protein levels and activity in exon-1 mouse models of Huntington's disease: role in excitotoxicity.

artículo científico publicado en 2009

Regulation of hippocampal cGMP levels as a candidate to treat cognitive deficits in Huntington's disease

artículo científico publicado en 2013

Striatal-enriched protein tyrosine phosphatase expression and activity in Huntington's disease: a STEP in the resistance to excitotoxicity

artículo científico publicado en 2011

Targeting CAG repeat RNAs reduces Huntington's disease phenotype independently of huntingtin levels.

artículo científico publicado en 2016

The AMPA receptor positive allosteric modulator S 47445 rescues in vivo CA3-CA1 long-term potentiation and structural synaptic changes in old mice.

artículo científico publicado en 2017

Lista de obras de Albert Giralt

7,8-dihydroxyflavone ameliorates cognitive and motor deficits in a Huntington's disease mouse model through specific activation of the PLCγ1 pathway

A role for Kalirin-7 in corticostriatal synaptic dysfunction in Huntington's disease

Activation of Elk-1 participates as a neuroprotective compensatory mechanism in models of Huntington's disease

Acute drug-induced spine changes in the nucleus accumbens are dependent on β-adducin.

Age-dependent decline of motor neocortex but not hippocampal performance in heterozygous BDNF mice correlates with a decrease of cortical PSD-95 but an increase of hippocampal TrkB levels.

Age-dependent maintenance of motor control and corticostriatal innervation by death receptor 3.

Age-related changes in STriatal-Enriched protein tyrosine Phosphatase levels: Regulation by BDNF.

Astrocytic BDNF and TrkB regulate severity and neuronal activity in mouse models of temporal lobe epilepsy

BDNF regulation under GFAP promoter provides engineered astrocytes as a new approach for long-term protection in Huntington's disease.

Brain-derived neurotrophic factor modulates the severity of cognitive alterations induced by mutant huntingtin: involvement of phospholipaseCgamma activity and glutamate receptor expression

Caveolin-1 deficiency causes cholesterol-dependent mitochondrial dysfunction and apoptotic susceptibility.

Cognitive Dysfunction in Huntington's Disease: Humans, Mouse Models and Molecular Mechanisms

Conditional BDNF Delivery from Astrocytes Rescues Memory Deficits, Spine Density, and Synaptic Properties in the 5xFAD Mouse Model of Alzheimer Disease

Conditional BDNF release under pathological conditions improves Huntington's disease pathology by delaying neuronal dysfunction

Cryostat Slice Irregularities May Introduce Bias in Tissue Thickness Estimation: Relevance for Cell Counting Methods.

Cyclin-Dependent Kinase 5 Dysfunction Contributes to Depressive-like Behaviors in Huntington's Disease by Altering the DARPP-32 Phosphorylation Status in the Nucleus Accumbens

Cytotoxic effect of neuromyelitis optica antibody (NMO-IgG) to astrocytes: an in vitro study

DARPP-32 interaction with adducin may mediate rapid environmental effects on striatal neurons

Differential neuroprotective effects of 5'-deoxy-5'-methylthioadenosine

Disease-specific phenotypes in dopamine neurons from human iPS-based models of genetic and sporadic Parkinson's disease.

Disruption of striatal glutamatergic transmission induced by mutant huntingtin involves remodeling of both postsynaptic density and NMDA receptor signaling

Dissociation between CA3-CA1 synaptic plasticity and associative learning in TgNTRK3 transgenic mice.

Early Downregulation of p75NTR by Genetic and Pharmacological Approaches Delays the Onset of Motor Deficits and Striatal Dysfunction in Huntington's Disease Mice.

Early L-dopa, but not pramipexole, restores basal ganglia activity in partially 6-OHDA-lesioned rats

Fingolimod (FTY720) enhances hippocampal synaptic plasticity and memory in Huntington's disease by preventing p75NTR up-regulation and astrocyte-mediated inflammation.

Helios expression coordinates the development of a subset of striatopallidal medium spiny neurons

Helios modulates the maturation of a CA1 neuronal subpopulation required for spatial memory formation

Imbalance of p75(NTR)/TrkB protein expression in Huntington's disease: implication for neuroprotective therapies.

Increased PKA signaling disrupts recognition memory and spatial memory: role in Huntington's disease

Long-term memory deficits in Huntington's disease are associated with reduced CBP histone acetylase activity.

Loss of striatal 90-kDa ribosomal S6 kinase (Rsk) is a key factor for motor, synaptic and transcription dysfunction in Huntington's disease

Neurobehavioral characterization of Endonuclease G knockout mice reveals a new putative molecular player in the regulation of anxiety

Neurotrophin receptor p75(NTR) mediates Huntington's disease-associated synaptic and memory dysfunction

PDE10 inhibition increases GluA1 and CREB phosphorylation and improves spatial and recognition memories in a Huntington's disease mouse model

PH domain leucine-rich repeat protein phosphatase 1 contributes to maintain the activation of the PI3K/Akt pro-survival pathway in Huntington's disease striatum.

PKR knockout in the 5xFAD model of Alzheimer's disease reveals beneficial effects on spatial memory and brain lesions.

PTK2B/Pyk2 overexpression improves a mouse model of Alzheimer's disease.

Prostaglandin E2 EP1 receptor antagonist improves motor deficits and rescues memory decline in R6/1 mouse model of Huntington's disease

Prostaglandin E2 EP2 activation reduces memory decline in R6/1 mouse model of Huntington's disease by the induction of BDNF-dependent synaptic plasticity.

Pyk2 in the amygdala modulates chronic stress sequelae via PSD-95-related micro-structural changes

Pyk2 is essential for astrocytes mobility following brain lesion

Pyk2 modulates hippocampal excitatory synapses and contributes to cognitive deficits in a Huntington's disease model

Reduced calcineurin protein levels and activity in exon-1 mouse models of Huntington's disease: role in excitotoxicity.

Regulation of hippocampal cGMP levels as a candidate to treat cognitive deficits in Huntington's disease

Striatal-enriched protein tyrosine phosphatase expression and activity in Huntington's disease: a STEP in the resistance to excitotoxicity

Targeting CAG repeat RNAs reduces Huntington's disease phenotype independently of huntingtin levels.

The AMPA receptor positive allosteric modulator S 47445 rescues in vivo CA3-CA1 long-term potentiation and structural synaptic changes in old mice.