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Lista de obras de Craig A McArdle

A new photoreactive antagonist cross-links to the N-terminal domain of the gonadotropin-releasing hormone receptor

artículo científico publicado en 1999

ATP-mediated killing of Mycobacterium bovis bacille Calmette-Guérin within human macrophages is calcium dependent and associated with the acidification of mycobacteria-containing phagosomes.

artículo científico publicado en 2001

Acute desensitization of phospholipase C-coupled muscarinic M3 receptors but not gonadotropin-releasing hormone receptors co-expressed in alphaT3-1 cells: implications for mechanisms of rapid desensitization

artículo científico publicado en 1998

Agonist-induced internalization and desensitization of the apelin receptor.

artículo científico publicado en 2016

Agonist-induced internalization and downregulation of gonadotropin-releasing hormone receptors

artículo científico publicado en 2009

Arrestin-mediated ERK activation by gonadotropin-releasing hormone receptors: receptor-specific activation mechanisms and compartmentalization

artículo científico publicado en 2005

Asn102 of the gonadotropin-releasing hormone receptor is a critical determinant of potency for agonists containing C-terminal glycinamide

artículo científico publicado en 1996

C-type natriuretic peptide (CNP) effects in anterior pituitary cell lines: evidence for homologous desensitisation of CNP-stimulated cGMP accumulation in alpha T3-1 gonadotroph-derived cells

artículo científico publicado en 2000

C-type natriuretic peptide (CNP) effects on intracellular calcium [Ca2+]i in mouse gonadotrope-derived alphaT3-1 cell line

artículo científico publicado en 1999

C-type natriuretic peptide (CNP) in the pituitary: is CNP an autocrine regulator of gonadotropes?

artículo científico publicado en 1994

C-type natriuretic peptide: an important neuroendocrine regulator?

artículo científico publicado en 2000

Ca2+ entry in gonadotrophs and alpha T3-1 cells: does store-dependent Ca2+ influx mediate gonadotrophin-releasing hormone action?

artículo científico publicado en 1996

Central role for protein kinase C in oxytocin and epidermal growth factor stimulated cyclooxygenase 2 expression in human myometrial cells

artículo científico publicado en 2014

Chronic regulation of ovarian oxytocin and progesterone release by prostaglandins: opposite effects in bovine granulosa and early luteal cells

artículo científico publicado en 1990

Cyclic guanosine monophosphate production in the pituitary: stimulation by C-type natriuretic peptide and inhibition by gonadotropin-releasing hormone in alpha T3-1 cells

artículo científico publicado en 1993

Decoding GnRH neurohormone pulse frequency by convergent signalling modules

artículo científico publicado en 2011

Decoding neurohormone pulse frequency by convergent signalling modules.

artículo científico

Dependence of gonadotropin-releasing hormone-stimulated luteinizing hormone release upon intracellular Ca2+ pools is revealed by desensitization and thapsigargin blockade

artículo científico publicado en 1992

Desensitization and internalization of human and xenopus gonadotropin-releasing hormone receptors expressed in alphaT4 pituitary cells using recombinant adenovirus

artículo científico publicado en 2000

Desensitization of gonadotropin-releasing hormone action in alphaT3-1 cells due to uncoupling of inositol 1,4,5-trisphosphate generation and Ca2+ mobilization

artículo científico publicado en 1996

Desensitization of gonadotropin-releasing hormone action in the gonadotrope-derived alpha T3-1 cell line

artículo científico publicado en 1995

Differential internalization of mammalian and non-mammalian gonadotropin-releasing hormone receptors. Uncoupling of dynamin-dependent internalization from mitogen-activated protein kinase signaling

artículo científico publicado en 2001

Differential sensitivity of agonist- and antagonist-occupied gonadotropin-releasing hormone receptors to protein kinase C activators. A marker for receptor activation

artículo científico publicado en 1988

Distinct kinin-induced functions are altered in circulating cells of young type 1 diabetic patients

artículo científico publicado en 2010

Dual specificity phosphatases 10 and 16 are positive regulators of EGF-stimulated ERK activity: indirect regulation of ERK signals by JNK/p38 selective MAPK phosphatases

artículo científico publicado en 2012

Dynamic video imaging of cystolic Ca(2+) in the alphaT3-1, gonadotrope-derived cell line

artículo científico publicado en 1992

ERK phosphorylation and nuclear accumulation: insights from single-cell imaging

artículo científico publicado en 2012

Effects of extracellular nucleotides in the pituitary: adenosine triphosphate receptor-mediated intracellular responses in gonadotrope-derived alpha T3-1 cells.

artículo científico publicado en 1996

Effects of gonadotropins, insulin and insulin-like growth factor I on ovarian oxytocin and progesterone production

scientific article published on 01 July 1991

Effects of pituitary adenylate cyclase-activating polypeptide in the pituitary: activation of two signal transduction pathways in the gonadotrope-derived alpha T3-1 cell line

artículo científico publicado en 1994

Encoding and decoding mechanisms of pulsatile hormone secretion.

artículo científico publicado en 2010

Endomorphin-2: a biased agonist at the μ-opioid receptor.

artículo científico publicado en 2012

Enhanced responsiveness of gonadotropes after protein kinase-C activation: postreceptor regulation of gonadotropin releasing hormone action

artículo científico publicado en 1988

Epidermal growth factor receptor and protein kinase C signaling to ERK2: spatiotemporal regulation of ERK2 by dual specificity phosphatases

artículo científico publicado en 2008

Estradiol regulates gonadotropin-releasing hormone receptor number, growth and inositol phosphate production in alpha T3-1 cells

artículo científico publicado en 1992

Evidence for a role of pituitary ATP receptors in the regulation of pituitary function

artículo científico publicado en 1995

Functional interaction between gonadotropin-releasing hormone and PACAP in gonadotropes and alpha T3-1 cells.

artículo científico publicado en 1996

GABAA receptor mediated elevation of Ca2+ and modulation of gonadotrophin-releasing hormone action in alphaT3-1 gonadotropes.

artículo científico publicado en 2000

GnRH and PACAP action in gonadotropes: cross-talk between phosphoinositidase C and adenylyl cyclase mediated signaling pathways

artículo científico publicado en 1996

Gonadotropin-Releasing Hormone Receptor Signaling: Biased and Unbiased

artículo científico publicado el 1 de agosto de 2012

Gonadotropin-releasing hormone and pituitary adenylate cyclase-activating polypeptide affect levels of cyclic adenosine 3',5'-monophosphate-dependent protein kinase A (PKA) subunits in the clonal gonadotrope alphaT3-1 cells: evidence for cross-talk

scientific article published on 01 June 1997

Gonadotropin-releasing hormone and protein kinase C signaling to ERK: spatiotemporal regulation of ERK by docking domains and dual-specificity phosphatases

artículo científico publicado en 2009

Gonadotropin-releasing hormone signaling: An information theoretic approach.

artículo científico publicado en 2017

Homologous and heterologous desensitization of guanylyl cyclase-B signaling in GH3 somatolactotropes

artículo científico publicado en 2013

Homologous down-regulation of gonadotropin-releasing hormone receptors and desensitization of gonadotropes: lack of dependence on protein kinase C

scientific article published on 01 June 1987

Hormone-stimulated redistribution of gonadotrope protein kinase C in vivo: dependence on Ca2+ influx

artículo científico publicado en 1986

IGFBP-1 expression is reduced in human type 2 diabetic glomeruli and modulates β1-integrin/FAK signalling in human podocytes

artículo científico publicado en 2021

Incorporation of an additional glycosylation site enhances expression of functional human gonadotropin-releasing hormone receptor

artículo científico publicado en 1996

Information Transfer in Gonadotropin-releasing Hormone (GnRH) Signaling: EXTRACELLULAR SIGNAL-REGULATED KINASE (ERK)-MEDIATED FEEDBACK LOOPS CONTROL HORMONE SENSING.

artículo científico publicado en 2015

Information transfer by leaky, heterogeneous, protein kinase signaling systems

artículo científico publicado en 2014

Inhibition of intracellular Ca2+ mobilisation by low antiproliferative concentrations of thapsigargin in human vascular smooth-muscle cells

scientific article published on 01 February 1999

Insulin signaling to the glomerular podocyte is critical for normal kidney function

artículo científico publicado en 2010

Internalization and desensitization of the oxytocin receptor is inhibited by Dynamin and clathrin mutants in human embryonic kidney 293 cells

artículo científico publicado en 2005

Internalization of gonadotropin-releasing hormone receptors (GnRHRs): does arrestin binding to the C-terminal tail target GnRHRs for dynamin-dependent internalization?

artículo científico publicado en 2005

Intracellular gonadotropin-releasing hormone receptors in breast cancer and gonadotrope lineage cells

artículo científico publicado en 2006

Involvement of PKC alpha and G-protein-coupled receptor kinase 2 in agonist-selective desensitization of mu-opioid receptors in mature brain neurons.

artículo científico publicado en 2009

Kisspeptin receptor agonist has therapeutic potential for female reproductive disorders

artículo científico publicado en 2020

Loss-of-function mutations in PNPLA6 encoding neuropathy target esterase underlie pubertal failure and neurological deficits in Gordon Holmes syndrome

artículo científico publicado en 2014

Mathematical modeling of gonadotropin-releasing hormone signaling

artículo científico publicado en 2016

Mechanism of action of gonadotropin releasing hormone

artículo científico publicado en 1986

Mechanisms of GnRH-induced extracellular signal-regulated kinase nuclear localization

artículo científico publicado en 2012

Molecular characterisation and functional interrogation of a local natriuretic peptide system in rodent pituitaries, alphaT3-1 and LbetaT2 gonadotroph cells

scientific journal article

Molecular mechanisms of gonadotropin-releasing hormone signaling: integrating cyclic nucleotides into the network.

artículo científico publicado en 2013

Na+ dependence of gonadotropin-releasing hormone action: characterization of the Na+/H+ antiport in pituitary gonadotropes

artículo científico publicado en 1991

Natriuretic peptides stimulate cyclic GMP production in an immortalized LHRH neuronal cell line

artículo científico publicado en 1994

Oestradiol is a potent mitogen and modulator of GnRH signalling in alphaT3-1 cells: are these effects causally related?

artículo científico publicado en 2000

Oxytocin and progesterone release from bovine corpus luteal cells in culture: effects of insulin-like growth factor I, insulin, and prostaglandins

artículo científico publicado en 1989

Oxytocin production and oxytocin messenger ribonucleic acid levels in bovine granulosa cells are regulated by insulin and insulin-like growth factor-I: dependence on developmental status of the ovarian follicle

artículo científico publicado en 1989

Oxytocin receptor-mediated activation of phosphoinositidase C and elevation of cytosolic calcium in the gonadotrope-derived alphaT3-1 cell line

artículo científico publicado en 1997

Oxytocin-stimulated NFAT transcriptional activation in human myometrial cells.

artículo científico publicado en 2012

PAC1 and PACAP expression, signaling, and effect on the growth of HCT8, human colonic tumor cells.

artículo científico publicado en 2002

Phorbol esters reduce gonadotrope responsiveness to protein kinase C activators but not to Ca2+-mobilizing secretagogues. Does protein kinase C mediate gonadotropin-releasing hormone action?

artículo científico publicado en 1987

Pituitary ATP receptors: characterization and functional localization to gonadotropes

scientific article published on 01 September 1994

Pituitary adenylate cyclase-activating peptide and vasoactive intestinal peptide receptor expression in immortalized LHRH neurons

artículo científico publicado en 1997

Pituitary adenylate cyclase-activating polypeptide (PACAP) actions on alphaT3-1 gonadotrophs show desensitization

artículo científico publicado en 1997

Pituitary adenylate cyclase-activating polypeptide effects in pituitary cells: modulation by gonadotropin-releasing hormone in alpha T3-1 cells

artículo científico publicado en 1994

Pituitary adenylate cyclase-activating polypeptide: a key player in reproduction?

scientific article published on 01 September 1994

Plasma membrane expression of GnRH receptors: regulation by antagonists in breast, prostate, and gonadotrope cell lines

artículo científico publicado en 2008

Plasma membrane expression of gonadotropin-releasing hormone receptors: regulation by peptide and nonpeptide antagonists

artículo científico publicado en 2009

Potential use of an estrogen-glucocorticoid receptor chimera as a drug screen for tissue selective estrogenic activity

artículo científico publicado en 2008

Pulsatile and sustained gonadotropin-releasing hormone (GnRH) receptor signaling: does the Ca2+/NFAT signaling pathway decode GnRH pulse frequency?

artículo científico publicado en 2009

Pulsatile and sustained gonadotropin-releasing hormone (GnRH) receptor signaling: does the ERK signaling pathway decode GnRH pulse frequency?

artículo científico publicado en 2010

Pulsatile hormonal signaling to extracellular signal-regulated kinase: exploring system sensitivity to gonadotropin-releasing hormone pulse frequency and width

scientific article published on 30 January 2014

Rapid down-regulation of the type I inositol 1,4,5-trisphosphate receptor and desensitization of gonadotropin-releasing hormone-mediated Ca2+ responses in alpha T3-1 gonadotropes

artículo científico publicado en 2000

Recurrent melanoma after topical tretinoin.

artículo científico publicado en 1989

Regulation of gonadotropin-releasing hormone receptors by protein kinase C: inside out signalling and evidence for multiple active conformations

artículo científico publicado en 2004

Relative roles of calcium derived from intra- and extracellular sources in dynamic luteinizing hormone release from perifused pituitary cells

artículo científico publicado en 1987

Rescue of expression and signaling of human luteinizing hormone G protein-coupled receptor mutants with an allosterically binding small-molecule agonist

artículo científico publicado en 2011

Selective translocation of non-conventional protein kinase C isoenzymes by gonadotropin-releasing hormone (GnRH) in the gonadotrope-derived alpha T3-1 cell line

artículo científico publicado en 1996

Seven-transmembrane receptor signalling and ERK compartmentalization.

artículo científico publicado en 2006

Signaling and antiproliferative effects mediated by GnRH receptors after expression in breast cancer cells using recombinant adenovirus

artículo científico publicado en 2001

Signaling and antiproliferative effects of type I and II gonadotropin-releasing hormone receptors in breast cancer cells

artículo científico publicado en 2004

Signaling to extracellular signal-regulated kinase from ErbB1 kinase and protein kinase C: feedback, heterogeneity, and gating

artículo científico publicado en 2013

Signalling and anti-proliferative effects mediated by gonadotrophin-releasing hormone receptors after expression in prostate cancer cells using recombinant adenovirus

artículo científico publicado en 2003

Signalling, cycling and desensitisation of gonadotrophin-releasing hormone receptors.

artículo científico publicado en 2002

Spatiotemporal regulation of ERK2 by dual specificity phosphatases

artículo científico publicado en 2008

Steroid receptor co-activator interacting protein (SIP) mediates EGF-stimulated expression of the prostaglandin synthase COX2 and prostaglandin release in human myometrium

artículo científico publicado en 2016

Stimulus-induced uncoupling of extracellular signal-regulated kinase phosphorylation from nuclear localization is dependent on docking domain interactions

artículo científico publicado en 2010

The Concise Guide to PHARMACOLOGY 2013/14: overview

artículo científico publicado en 2013

The Concise Guide to PHARMACOLOGY 2015/16: Overview

artículo científico publicado en 2015

The circus in the pituitary

artículo científico publicado en 2001

The gonadotrophin-releasing hormone receptor: signalling, cycling and desensitisation

artículo científico publicado en 2002

The human gonadotropin releasing hormone type I receptor is a functional intracellular GPCR expressed on the nuclear membrane

artículo científico publicado en 2010

The lack of gonadotrophin-releasing hormone (GnRH) receptor desensitisation in alphaT3-1 cells is not due to GnRH receptor reserve or phosphatidylinositol 4,5-bis-phosphate pool size

artículo científico publicado en 1999

The molecular basis of gonadotropin-releasing hormone (GnRH) action in the pituitary gonadotrope

artículo científico publicado en 1987

The molecular mechanism of action of gonadotropin releasing hormone (GnRH) in the pituitary

artículo científico publicado en 1987

The regulation of oxytocin gene expression in early bovine luteal cells

scientific article published on 01 March 1990

The tail of the gonadotrophin-releasing hormone receptor: desensitization at, and distal to, G protein-coupled receptors.

artículo científico publicado en 1999

Use of protein kinase C-depleted cells for investigation of the role of protein kinase C in stimulus-response coupling in the pituitary

scientific article published on 01 January 1989

Using automated imaging to interrogate gonadotrophin-releasing hormone receptor trafficking and function.

artículo científico publicado en 2010

Using high-content microscopy to study gonadotrophin-releasing hormone regulation of ERK.

artículo científico publicado en 2010

Will GnRH antagonists improve prostate cancer treatment?

artículo científico publicado en 2008