Lista de obras - Manel Esteller - Dominio Público Uruguay

109 A novel Werner Syndrome mutation: Pharmacological treatment by read-through of nonsense mutations and epigenetic therapies

scholarly article by A. Ruben et al published September 2015 in European Journal of Cancer

31st Annual Meeting and Associated Programs of the Society for Immunotherapy of Cancer (SITC 2016): part one

artículo científico publicado en 2016

5'-CpG island methylation of the LKB1/STK11 promoter and allelic loss at chromosome 19p13.3 in sporadic colorectal cancer

artículo científico publicado en 2000

A Combined Epigenetic Therapy Equals the Efficacy of Conventional Chemotherapy in Refractory Advanced Non-Small Cell Lung Cancer

artículo científico publicado en 2011

A Comprehensive DNA Methylation Profile of Epithelial-to-Mesenchymal Transition

scientific article published on 08 August 2014

A CpG island hypermethylation profile of primary colorectal carcinomas and colon cancer cell lines

artículo científico publicado en 2004

A DERL3-associated defect in the degradation of SLC2A1 mediates the Warburg effect

artículo científico publicado en 2014

A DNA methylation fingerprint of 1628 human samples

artículo científico publicado en 2011

A DNA methylation map of human cancer at single base-pair resolution.

artículo científico publicado en 2017

A DNA methylation-based definition of biologically distinct breast cancer subtypes

artículo científico publicado en 2014

A Novel Epigenetic Signature for Early Diagnosis in Lung Cancer

artículo científico publicado en 2016

A Prognostic DNA Methylation Signature for Stage I Non–Small-Cell Lung Cancer

article

A gene hypermethylation profile of human cancer

artículo científico publicado en 2001

A genetic defect in exportin-5 traps precursor microRNAs in the nucleus of cancer cells

artículo científico publicado en 2010

A landscape of pharmacogenomic interactions in cancer.

artículo científico publicado en 2016

A microRNA DNA methylation signature for human cancer metastasis

artículo científico publicado en 2008

A microarray-based DNA methylation study of glioblastoma multiforme

artículo científico publicado en 2009

A mouse skin multistage carcinogenesis model reflects the aberrant DNA methylation patterns of human tumors

artículo científico publicado en 2004

A multiplatform approach identifies miR-152-3p as a common epigenetically regulated onco-suppressor in prostate cancer targeting TMEM97.

artículo científico publicado en 2018

A mutation in the POT1 gene is responsible for cardiac angiosarcoma in TP53-negative Li-Fraumeni-like families

artículo científico publicado en 2015

A novel Werner Syndrome mutation: pharmacological treatment by read-through of nonsense mutations and epigenetic therapies

artículo científico publicado en 2015

A precursor microRNA in a cancer cell nucleus: get me out of here!

artículo científico publicado en 2011

A predictor based on the somatic genomic changes of the BRCA1/BRCA2 breast cancer tumors identifies the non-BRCA1/BRCA2 tumors with BRCA1 promoter hypermethylation

article

A profile of methyl-CpG binding domain protein occupancy of hypermethylated promoter CpG islands of tumor suppressor genes in human cancer

artículo científico publicado en 2006

A role for RNAi in the selective correction of DNA methylation defects.

artículo científico publicado en 2009

A role for methyl-CpG binding domain protein 2 in the modulation of the estrogen response of pS2/TFF1 gene

artículo científico publicado en 2010

A systematic profile of DNA methylation in human cancer cell lines

artículo científico publicado en 2003

A truncating mutation of HDAC2 in human cancers confers resistance to histone deacetylase inhibition

artículo científico publicado en 2006

A two-gene epigenetic signature for the prediction of response to neoadjuvant chemotherapy in triple-negative breast cancer patients

article

Aberrant DNA methylation as a cancer-inducing mechanism

artículo científico publicado en 2005

Aberrant DNA methylation in non-small cell lung cancer-associated fibroblasts

artículo científico publicado en 2015

Aberrant DNA methylation profiles in the premature aging disorders Hutchinson-Gilford Progeria and Werner syndrome

artículo científico publicado en 2012

Aberrant epigenetic landscape in cancer: how cellular identity goes awry

artículo científico publicado en 2010

Aberrant epigenetic landscape in intellectual disability.

artículo científico publicado en 2012

Aberrant patterns of DNA methylation, chromatin formation and gene expression in cancer

artículo científico publicado en 2001

Aberrant promoter methylation of multiple genes throughout the clinico-pathologic spectrum of B-cell neoplasia.

artículo científico publicado en 2004

Aberrant promoter methylation of the transcription factor genes PAX5 alpha and beta in human cancers.

artículo científico publicado en 2003

Aberrant regulation of messenger RNA 3'-untranslated region in human cancer.

artículo científico publicado en 2007

Abnormal PcG protein expression in Hodgkin's lymphoma. Relation with E2F6 and NFkappaB transcription factors.

artículo científico publicado en 2004

Abnormalities of E- and P-cadherin and catenin (β-, γ-catenin, and p120ctn) expression in endometrial cancer and endometrial atypical hyperplasia

Abnormalities of the APC/beta-catenin pathway in endometrial cancer

artículo científico publicado en 2002

Absence of Maternal Methylation in Biparental Hydatidiform Moles from Women with NLRP7 Maternal-Effect Mutations Reveals Widespread Placenta-Specific Imprinting.

artículo científico publicado en 2015

Abstract 2130A: Epigenetic silencing of TGFβ1, BCL6, KILLIN and CTSZ is related to trastuzumab resistance in HER2-positive breast cancer models

Abstract 2763: DNA methylation profiling unveils TGF-β hyperresponse in tumor associated fibroblasts from lung cancer patients

Abstract 2770: DERL3 hypermethylation alters rhabdomyosarcoma cell metabolism

Abstract 3820: Epigenetic re-expression of fetal IGF2 as therapeutic target in hepatocellular carcinoma

Abstract 3883: Clonal evolution of a lethal prostate cancer: Integrated whole genome analysis case study

Abstract 432: Loss of MGMT promoter methylation and resistance to cisplatin in non-seminomatous germ cell tumors

Abstract 4734: miR-9-5p expression in breast cancer correlates with hormone receptor status and affects patients survival

Abstract 4784: Effect of epigenetic drugs on chromatin remodeling complexes disrupted in cancer

Abstract 5394: Initial results from TRANSCAN ERA-NET BREMIR project: MicroRNAs expression profiling for identification of breast cancer patients at high risk to develop distant metastases

Abstract 5483: Implications of the type ofBRCA1germline mutation in the treatment of patients with hereditary breast cancer

Abstract A40: Epigenomic profiling identifies NCRNAs as novel tumor suppressors in developmental tumors

Abstract IA19: Cancer epigenomics: From knowledge to applications

Abstract LB-155: Identification of a DNA methylation signature in liquid biopsy for early non-small cell lung cancer (NSCLC) diagnosis

article published in 2016

Advances in the molecular genetics of endometrial cancer (Review).

artículo científico publicado en 1999

Allele-specific histone lysine methylation marks regulatory regions at imprinted mouse genes

artículo científico publicado en 2002

Alterations of the p16INK4a/Rb/cyclin-D1 pathway in vulvar carcinoma, vulvar intraepithelial neoplasia, and lichen sclerosus

Altered expression of adhesion molecules and epithelial-mesenchymal transition in silica-induced rat lung carcinogenesis

artículo científico publicado en 2004

Altered expression of the imprinted transcription factor PLAGL1 deregulates a network of genes in the human IUGR placenta

artículo científico publicado en 2014

An Adenine Code for DNA: A Second Life for N6-Methyladenine

artículo científico

An increase in MECP2 dosage impairs neural tube formation

artículo científico publicado en 2014

An integrated epigenomic analysis for type 2 diabetes susceptibility loci in monozygotic twins

artículo científico publicado en 2014

An integrated genomic analysis of anaplastic meningioma identifies prognostic molecular signatures

scientific article published in Scientific Reports

An integrated genomic analysis of anaplastic meningioma identifies prognostic molecular signatures

Analysis of adenomatous polyposis coli promoter hypermethylation in human cancer

article

Angiostatic activity of DNA methyltransferase inhibitors

artículo científico publicado en 2006

Antitumor activity of a small-molecule inhibitor of the histone kinase Haspin

artículo científico publicado en 2011

Arachidonic and oleic acid exert distinct effects on the DNA methylome.

artículo científico publicado en 2016

Arbitrarily Primed-PCR and Related DNA Methylation Methodologies

Array-based DNA methylation profiling in acute myeloid leukaemia.

artículo científico publicado en 2011

Array-based DNA-methylation profiling in sarcomas with small blue round cell histology provides valuable diagnostic information.

artículo científico publicado en 2018

Assessing associations between the AURKA-HMMR-TPX2-TUBG1 functional module and breast cancer risk in BRCA1/2 mutation carriers

artículo científico publicado en 2015

Associations between whole peripheral blood fatty acids and DNA methylation in humans

artículo científico publicado en 2016

At the crossroad of lifespan, calorie restriction, chromatin and disease: meeting on sirtuins

artículo científico publicado en 2010

B-cell leukemia transdifferentiation to macrophage involves reconfiguration of DNA methylation for long-range regulation

scientific article published on 12 November 2019

BCR-ABL1-induced expression of HSPA8 promotes cell survival in chronic myeloid leukaemia

artículo científico publicado en 2008

BLUEPRINT to decode the epigenetic signature written in blood.

artículo científico publicado en 2012

BMP Inhibition in Seminomas Initiates Acquisition of Pluripotency via NODAL Signaling Resulting in Reprogramming to an Embryonal Carcinoma

artículo científico publicado en 2015

BRCA1 CpG Island Hypermethylation Predicts Sensitivity to Poly(Adenosine Diphosphate)- Ribose Polymerase Inhibitors

BRCA1 as a tumor suppressor linked to the regulation of epigenetic states: keeping oncomiRs under control

artículo científico publicado en 2012

BRCA1 epigenetic inactivation predicts sensitivity to platinum-based chemotherapy in breast and ovarian cancer

artículo científico publicado en 2012

Barcelona Conference on Epigenetics and Cancer: 50 years of histone acetylation

artículo científico publicado en 2015

Beyond genetics--the emerging role of epigenetic changes in hematopoietic malignancies

artículo científico publicado en 2004

Bivalent histone modifications in stem cells poise miRNA loci for CpG island hypermethylation in human cancer

artículo científico publicado en 2011

Breast cancer epigenetics: from DNA methylation to microRNAs

artículo científico publicado en 2010

Bromodomain inhibition shows antitumoral activity in mice and human luminal breast cancer

artículo científico publicado en 2017

Bromodomain inhibitors and cancer therapy: From structures to applications

artículo científico publicado en 2016

CARM1 and BAF155: an example of how chromatin remodeling factors can be relocalized and contribute to cancer

artículo científico publicado en 2014

CD137 (4-1BB) Costimulation Modifies DNA Methylation in CD8+ T Cell-Relevant Genes.

artículo científico publicado en 2017

CHK2-decreased protein expression and infrequent genetic alterations mainly occur in aggressive types of non-Hodgkin lymphomas

artículo científico publicado en 2002

CHL1 hypermethylation as a potential biomarker of poor prognosis in breast cancer.

scientific article published on 02 February 2017

CSL-MAML-dependent Notch1 signaling controls T lineage-specific IL-7R{alpha} gene expression in early human thymopoiesis and leukemia

artículo científico publicado en 2009

CSL–MAML-dependent Notch1 signaling controls T lineage–specific IL-7Rα gene expression in early human thymopoiesis and leukemia.

artículo científico publicado en 2009

Cancer Epigenetics for the 21st Century: What's Next?

artículo científico

Cancer Stem-like Cells Act via Distinct Signaling Pathways in Promoting Late Stages of Malignant Progression.

artículo científico publicado en 2015

Cancer as an epigenetic disease: DNA methylation and chromatin alterations in human tumours

artículo científico publicado en 2002

Cancer epigenetics and methylation

artículo científico publicado en 2002

Cancer epigenetics reaches mainstream oncology ⬇️

artículo científico publicado el 1 de marzo de 2011

Cancer epigenetics: DNA methylation and chromatin alterations in human cancer

artículo científico publicado en 2003

Cancer epigenomics: DNA methylomes and histone-modification maps

artículo científico publicado en 2007

Cancer epigenomics: beyond genomics

artículo científico

Cancer genes hypermethylated in human embryonic stem cells

artículo científico publicado en 2008

Cancer genomics identifies disrupted epigenetic genes

artículo científico

Cancer network activity associated with therapeutic response and synergism

artículo científico publicado en 2016

Cancer, epigenetics and the Nobel Prizes

artículo científico publicado en 2012

Capillary electrophoresis-based method to quantitate DNA–protein interactions ⬇️

artículo científico publicado el 15 de junio de 2003

Caveolin-1 is down-regulated in alveolar rhabdomyosarcomas and negatively regulates tumor growth

artículo científico publicado en 2014

Changes in the pattern of DNA methylation associate with twin discordance in systemic lupus erythematosus

artículo científico publicado en 2009

Characterization of 8p21.3 chromosomal deletions in B-cell lymphoma: TRAIL-R1 and TRAIL-R2 as candidate dosage-dependent tumor suppressor genes.

artículo científico publicado en 2005

Checkpoint kinase 1 (CHK1) protein and mRNA expression is downregulated in aggressive variants of human lymphoid neoplasms

artículo científico publicado en 2005

Chromatin remodeling factor CHD5 is silenced by promoter CpG island hypermethylation in human cancer

artículo científico publicado en 2008

Chromatin remodeling in mammary gland differentiation and breast tumorigenesis

artículo científico publicado en 2010

Chromosomal instability correlates with genome-wide DNA demethylation in human primary colorectal cancers.

artículo científico publicado en 2006

Circadian cycle-dependent MeCP2 and brain chromatin changes

artículo científico publicado en 2015

Cis-acting noncoding RNAs: friends and foes

artículo científico publicado en 2012

Clinical and molecular analyses of Beckwith-Wiedemann syndrome: Comparison between spontaneous conception and assisted reproduction techniques.

artículo científico publicado en 2016

Clinical epigenetics: seizing opportunities for translation

artículo científico publicado en 2019

Clinicopathologic features and genetic alterations in endometrioid carcinoma of the uterus with villoglandular differentiation

Clustering of gene hypermethylation associated with clinical risk groups in neuroblastoma

artículo científico publicado en 2004

Combinatorial effects of splice variants modulate function of Aiolos

artículo científico publicado en 2007

Commensal-Specific CD4(+) Cells From Patients With Crohn's Disease Have a T-Helper 17 Inflammatory Profile.

artículo científico publicado en 2016

Common genetic evolutionary pathways in familial adenomatous polyposis tumors

artículo científico publicado en 2003

Comparative genome-wide DNA methylation analysis of colorectal tumor and matched normal tissues.

artículo científico publicado en 2012

Comprehensive DNA methylation study identifies novel progression-related and prognostic markers for cutaneous melanoma

artículo científico publicado en 2017

Copy number rather than epigenetic alterations are the major dictator of imprinted methylation in tumors

artículo científico publicado en 2017

Correction to: DNA methylation-based reclassification of olfactory neuroblastoma

artículo científico publicado en 2018

Corrigendum: A DERL3-associated defect in the degradation of SLC2A1 mediates the Warburg effect

artículo científico publicado en 2016

CpG island hypermethylation and tumor suppressor genes: a booming present, a brighter future

artículo científico publicado en 2002

CpG island hypermethylation of BRCA1 and loss of pRb as co-occurring events in basal/triple-negative breast cancer

artículo científico publicado en 2011

CpG island hypermethylation of the DNA repair enzyme methyltransferase predicts response to temozolomide in primary gliomas

artículo científico publicado en 2004

CpG island hypermethylation of tumor suppressor microRNAs in human cancer

artículo científico publicado en 2007

CpG island hypermethylation-associated silencing of non-coding RNAs transcribed from ultraconserved regions in human cancer

artículo científico publicado en 2010

CpG island hypermethylation-associated silencing of small nucleolar RNAs in human cancer

artículo científico publicado en 2012

CpG island methylation and histone modifications: biology and clinical significance.

artículo científico publicado en 2006

CpG island promoter hypermethylation of the Ras-effector gene NORE1A occurs in the context of a wild-type K-ras in lung cancer

artículo científico publicado en 2004

CpG island promoter hypermethylation of the pro-apoptotic gene caspase-8 is a common hallmark of relapsed glioblastoma multiforme.

artículo científico publicado en 2007

Cross-talk between aging and cancer: the epigenetic language

artículo científico publicado en 2007

Cyclooxygenase 2 Expression in Colorectal Cancer with DNA Mismatch Repair Deficiency

artículo científico publicado en 2006

DNA Hypermethylation in Somatic Cells Correlates with Higher Reprogramming Efficiency

DNA Methylation and Cancer

DNA Methylomes Reveal Biological Networks Involved in Human Eye Development, Functions and Associated Disorders

artículo científico publicado en 2017

DNA demethylating agents and chromatin-remodelling drugs: which, how and why?

artículo científico publicado en 2003

DNA hypomethylation affects cancer-related biological functions and genes relevant in neuroblastoma pathogenesis

artículo científico publicado en 2012

DNA methylation alterations in grade II- and anaplastic pleomorphic xanthoastrocytoma

artículo científico publicado en 2014

DNA methylation and cancer therapy: new developments and expectations

artículo científico publicado en 2005

DNA methylation and histone modifications in patients with cancer: potential prognostic and therapeutic targets

artículo científico publicado en 2007

DNA methylation and the functional organization of the nuclear compartment

artículo científico publicado en 2009

DNA methylation biomarkers for noninvasive diagnosis of colorectal cancer.

artículo científico publicado en 2013

DNA methylation contributes to natural human variation

artículo científico publicado en 2013

DNA methylation determines nucleosome occupancy in the 5'-CpG islands of tumor suppressor genes

artículo científico publicado en 2013

DNA methylation dynamics in human carotid plaques after cerebrovascular events

artículo científico publicado en 2015

DNA methylation in early neoplasia.

artículo científico

DNA methylation in stem cell renewal and multipotency

artículo científico publicado en 2011

DNA methylation map in circulating leukocytes mirrors subcutaneous adipose tissue methylation pattern: a genome-wide analysis from non-obese and obese patients.

artículo científico publicado en 2017

DNA methylation map of human atherosclerosis

artículo científico publicado en 2014

DNA methylation map of mouse and human brain identifies target genes in Alzheimer's disease.

artículo científico publicado en 2013

DNA methylation markers for prostate cancer with a stem cell twist

artículo científico publicado en 2010

DNA methylation patterns in hereditary human cancers mimic sporadic tumorigenesis

artículo científico publicado en 2001

DNA methylation plasticity contributes to the natural history of metastasis

artículo científico publicado en 2015

DNA methylation plasticity of human adipose-derived stem cells in lineage commitment

artículo científico publicado en 2012

DNA methylation polymorphisms precede any histological sign of atherosclerosis in mice lacking apolipoprotein E.

artículo científico publicado en 2004

DNA methylation profiles and their relationship with cytogenetic status in adult acute myeloid leukemia

artículo científico publicado en 2010

DNA methylation profiling identifies PTRF/Cavin-1 as a novel tumor suppressor in Ewing sarcoma when co-expressed with caveolin-1.

artículo científico publicado en 2016

DNA methylation profiling in breast cancer discordant identical twins identifies DOK7 as novel epigenetic biomarker

artículo científico publicado en 2012

DNA methylation profiling in the clinic: applications and challenges

artículo científico publicado en 2012

DNA methylation signal has a major role in the response of human breast cancer cells to the microenvironment.

artículo científico publicado en 2017

DNA methylation-associated silencing of tumor-suppressor microRNAs in cancer

artículo científico

DNA methylation-based prognosis and epidrivers in hepatocellular carcinoma

artículo científico publicado en 2015

DNA methylation-based reclassification of olfactory neuroblastoma

artículo científico publicado en 2018

DNA methylation: a profile of methods and applications

artículo científico publicado en 2002

DNA methylomes, histone codes and miRNAs: tying it all together

artículo científico publicado en 2008

DNA methyltransferases control telomere length and telomere recombination in mammalian cells

DNA repair capacity is impaired in healthy BRCA1 heterozygous mutation carriers

artículo científico publicado en 2015

DNMT3A mutations mediate the epigenetic reactivation of the leukemogenic factor MEIS1 in acute myeloid leukemia

artículo científico publicado en 2015

DNMT3A mutations mediate the epigenetic reactivation of the leukemogenic factor MEIS1 in acute myeloid leukemia.

artículo científico publicado en 2017

DNMT3B gene amplification predicts resistance to DNA demethylating drugs

artículo científico publicado en 2011

Defective IL-10 production in severe phenotypes of Crohn's disease.

artículo científico publicado en 2009

Detection of aberrant promoter hypermethylation of tumor suppressor genes in serum DNA from non-small cell lung cancer patients

article

Detection of c-erbB-2/neu and fibroblast growth factor-3/INT-2 but not epidermal growth factor receptor gene amplification in endometrial cancer by differential polymerase chain reaction

article

Detection of clonality and genetic alterations in endometrial pipelle biopsy and its surgical specimen counterpart

artículo científico publicado en 1997

Detection of lymph node micrometastases by gene promoter hypermethylation in samples obtained by endosonography- guided fine-needle aspiration biopsy

artículo científico publicado en 2004

Differences and molecular immunohistochemical parameters in the subtypes of infiltrating ductal breast cancer.

artículo científico publicado en 2008

Differential DNA hypermethylation and hypomethylation signatures in colorectal cancer

artículo científico publicado en 2004

Differential hypermethylation of genes in vulvar cancer and lichen sclerosus coexisting or not with vulvar cancer.

artículo científico publicado en 2010

Digital PCR quantification of MGMT methylation refines prediction of clinical benefit from alkylating agents in glioblastoma and metastatic colorectal cancer.

artículo científico publicado en 2015

Direct metabolic regulation of beta-catenin activity by the p85alpha regulatory subunit of phosphoinositide 3-OH kinase

artículo científico publicado en 2005

Discovery of epigenetically silenced genes by methylated DNA immunoprecipitation in colon cancer cells

artículo científico publicado en 2007

Discovery of methylated circulating DNA biomarkers for comprehensive non-invasive monitoring of treatment response in metastatic colorectal cancer

artículo científico publicado en 2017

Discovery of novel DNA methylation biomarkers for non-invasive sporadic breast cancer detection in the Latino population

artículo científico publicado en 2020

Discovery of salermide-related sirtuin inhibitors: binding mode studies and antiproliferative effects in cancer cells including cancer stem cells

artículo científico publicado en 2012

Disrupted microRNA expression caused by Mecp2 loss in a mouse model of Rett syndrome

artículo científico publicado en 2010

Disruption of NIPBL/Scc2 in Cornelia de Lange Syndrome provokes cohesin genome-wide redistribution with an impact in the transcriptome

artículo científico publicado en 2021

Disruption of microRNA nuclear transport in human cancer

artículo científico

Distinct DNA methylomes of newborns and centenarians

artículo científico publicado en 2012

Distinctive gene expression of human lung adenocarcinomas carrying LKB1 mutations.

artículo científico publicado en 2004

Dormant hypermethylated tumour suppressor genes: questions and answers

artículo científico publicado en 2005

Downregulation of miR-130b~301b cluster is mediated by aberrant promoter methylation and impairs cellular senescence in prostate cancer

scientific article published on 06 February 2017

Dynamic epigenetic regulation of the microRNA-200 family mediates epithelial and mesenchymal transitions in human tumorigenesis

artículo científico publicado en 2011

Dynamics of DNA methylation in recent human and great ape evolution

artículo científico publicado en 2013

Dynamics of bivalent chromatin domains upon drug induced reactivation and resilencing in cancer cells

artículo científico publicado en 2011

Dysregulation of microRNAs in cancer: playing with fire

artículo científico publicado en 2010

Dysregulation of the long non-coding RNA transcriptome in a Rett syndrome mouse model

artículo científico publicado en 2013

E47 phosphorylation by p38 MAPK promotes MyoD/E47 association and muscle-specific gene transcription

artículo científico publicado en 2005

EMP3, a myelin-related gene located in the critical 19q13.3 region, is epigenetically silenced and exhibits features of a candidate tumor suppressor in glioma and neuroblastoma.

artículo científico publicado en 2005

EPHA7, a new target gene for 6q deletion in T-cell lymphoblastic lymphomas

artículo científico publicado en 2011

EZH2-mediated epigenetic repression of DNA repair in promoting breast tumor initiating cells

artículo científico publicado en 2011

EZH2: an epigenetic gatekeeper promoting lymphomagenesis

artículo científico publicado en 2013

Early-onset and classical forms of type 2 diabetes show impaired expression of genes involved in muscle branched-chain amino acids metabolism

artículo científico publicado en 2017

Economic Analysis Of Epicup, An Epigenetic Test To Predict The Tissue Of Origin In Cancer Of Unknown Primary Site, From The Spanish Nhs Perspective

article

Economic Analysis Of Epicup, An Epigenetic Test To Predict The Tissue Of Origin In Cancer Of Unknown Primary Site, The Usa Payors Perspective

Effect of genetic ancestry on leukocyte global DNA methylation in cancer patients

artículo científico publicado en 2015

Effects of APOE-ε4 allele load on brain morphology in a cohort of middle-aged healthy individuals with enriched genetic risk for Alzheimer's disease.

artículo científico publicado en 2018

Endometrial carcinoma in tamoxifen-treated breast cancer patient: clinicopathological, immunohistochemical, and genetic analysis

scientific article published on 01 October 1999

Epigenetic Awakening of Viral Mimicry in Cancer

artículo científico publicado en 2020

Epigenetic Homogeneity Within Colorectal Tumors Predicts Shorter Relapse-Free and Overall Survival Times for Patients With Locoregional Cancer

artículo científico publicado en 2016

Epigenetic activation of SOX11 in lymphoid neoplasms by histone modifications.

artículo científico publicado en 2011

Epigenetic activation of a cryptic TBC1D16 transcript enhances melanoma progression by targeting EGFR

artículo científico publicado en 2015

Epigenetic alterations involved in cancer stem cell reprogramming

artículo científico publicado en 2012

Epigenetic alterations leading to TMPRSS4 promoter hypomethylation and protein overexpression predict poor prognosis in squamous lung cancer patients

artículo científico publicado en 2016

Epigenetic alterations of the Wnt/beta-catenin pathway in human disease

artículo científico publicado en 2007

Epigenetic and genetic alterations ofAPCandCDH1genes in lobular breast cancer: Relationships with abnormal E-cadherin and catenin expression and microsatellite instability

article

Epigenetic biomarkers for human cancer: the time is now.

artículo científico publicado en 2008

Epigenetic changes associated with neoplasms of the exocrine and endocrine pancreas

artículo científico publicado en 2014

Epigenetic changes in cancer

artículo científico publicado en 2011

Epigenetic connections between autoimmune disorders and haematological malignancies

artículo científico publicado en 2008

Epigenetic control of nuclear architecture

artículo científico publicado en 2007

Epigenetic control of somatostatin and cortistatin expression by β amyloid peptide.

artículo científico publicado en 2011

Epigenetic differences arise during the lifetime of monozygotic twins

artículo científico publicado en 2005

Epigenetic disruption of cadherin-11 in human cancer metastasis.

artículo científico publicado en 2012

Epigenetic disruption of ribosomal RNA genes and nucleolar architecture in DNA methyltransferase 1 (Dnmt1) deficient cells

artículo científico publicado en 2007

Epigenetic disruption of the PIWI pathway in human spermatogenic disorders

artículo científico publicado en 2012

Epigenetic drugs: More than meets the eye.

artículo científico publicado en 2017

Epigenetic gene regulation in cancer

artículo científico publicado en 2008

Epigenetic gene silencing in cancer: the DNA hypermethylome

artículo científico publicado en 2007

Epigenetic inactivation of LKB1 in primary tumors associated with the Peutz-Jeghers syndrome

Epigenetic inactivation of the BRCA1 interactor SRBC and resistance to oxaliplatin in colorectal cancer.

artículo científico publicado en 2013

Epigenetic inactivation of the ERK inhibitor Spry2 in B-cell diffuse lymphomas.

artículo científico publicado en 2008

Epigenetic inactivation of the Groucho homologue gene TLE1 in hematologic malignancies

artículo científico publicado en 2008

Epigenetic inactivation of the Sotos overgrowth syndrome gene histone methyltransferase NSD1 in human neuroblastoma and glioma

artículo científico publicado en 2009

Epigenetic inactivation of the Wnt antagonist DICKKOPF-1 (DKK-1) gene in human colorectal cancer

artículo científico publicado en 2006

Epigenetic inactivation of the circadian clock gene BMAL1 in hematologic malignancies.

artículo científico publicado en 2009

Epigenetic inactivation of the p53-induced long noncoding RNA TP53 target 1 in human cancer

artículo científico publicado en 2016

Epigenetic inactivation of the premature aging Werner syndrome gene in human cancer

artículo científico publicado en 2006

Epigenetic inactivation of the putative DNA/RNA helicase SLFN11 in human cancer confers resistance to platinum drugs

artículo científico publicado en 2015

Epigenetic inactivation of tumour suppressor coding and non-coding genes in human cancer: an update

artículo científico publicado en 2017

Epigenetic lesions causing genetic lesions in human cancer: promoter hypermethylation of DNA repair genes

artículo científico publicado en 2000

Epigenetic loss of RNA-methyltransferase NSUN5 in glioma targets ribosomes to drive a stress adaptive translational program

artículo científico publicado en 2019

Epigenetic loss of the PIWI/piRNA machinery in human testicular tumorigenesis

artículo científico publicado en 2013

Epigenetic loss of the RNA decapping enzyme NUDT16 mediates C-MYC activation in T-cell acute lymphoblastic leukemia.

artículo científico publicado en 2017

Epigenetic loss of the familial tumor-suppressor gene exostosin-1 (EXT1) disrupts heparan sulfate synthesis in cancer cells

artículo científico publicado en 2004

Epigenetic loss of the transfer RNA-modifying enzyme TYW2 induces ribosome frameshifts in colon cancer

artículo científico publicado en 2020

Epigenetic mechanisms during ageing and neurogenesis as novel therapeutic avenues in human brain disorders.

artículo científico publicado en 2017

Epigenetic mechanisms in neurological diseases: genes, syndromes, and therapies

artículo científico publicado en 2009

Epigenetic modifications and human disease

scientific article (publication date: October 2010)

Epigenetic modifications in breast cancer and their role in personalized medicine

artículo científico

Epigenetic profiling joins personalized cancer medicine

artículo científico

Epigenetic profiling to classify cancer of unknown primary: a multicentre, retrospective analysis

artículo científico publicado en 2016

Epigenetic regulation of miR-212 expression in lung cancer

artículo científico publicado en 2011

Epigenetic regulation of telomeres in human cancer.

artículo científico publicado en 2008

Epigenetic regulation of vitamin D metabolism in human lung adenocarcinoma

scientific article published on April 2014

Epigenetic repression of ROR2 has a Wnt-mediated, pro-tumourigenic role in colon cancer

artículo científico publicado en 2010

Epigenetic signatures associated with different levels of differentiation potential in human stem cells

artículo científico publicado en 2009

Epigenetic silencing of E- and N-cadherins in the stroma of mouse thymic lymphomas

Epigenetic-smoking interaction reveals histologically heterogeneous effects of TRIM27 DNA methylation on overall survival among early-stage NSCLC patients

scientific article published on 03 September 2020

Epigenetics and aging: the targets and the marks

artículo científico publicado en 2007

Epigenetics in Schizophrenia: A Pilot Study of Global DNA Methylation in Different Brain Regions Associated with Higher Cognitive Functions

artículo científico publicado en 2016

Epigenetics of breast cancer

artículo científico publicado en 2011

Epigenetics provides a new generation of oncogenes and tumour-suppressor genes

artículo científico publicado en 2006

Epigenetics provides a new generation of oncogenes and tumour-suppressor genes

article

Epigenome-wide three-way interaction study identifies a complex pattern between TRIM27, KIAA0226, and smoking associated with overall survival of early-stage NSCLC

artículo científico publicado en 2022

Epigenomic analysis detects aberrant super-enhancer DNA methylation in human cancer.

artículo científico publicado en 2016

Epigenomics of human colon cancer.

artículo científico publicado en 2010

Erratum: Corrigendum: A TARBP2 mutation in human cancer impairs microRNA processing and DICER1 function

scholarly article published in Nature Genetics

Erratum: Salermide, a Sirtuin inhibitor with a strong cancer-specific proapoptotic effect

scholarly article published in Oncogene

Erratum: The Polycomb group protein EZH2 directly controls DNA methylation

artículo científico publicado en 2007

Evaluation of responsive gene expression as a sensitive and specific biomarker in patients with ulcerative colitis

artículo científico publicado en 2013

Experimental and Bioinformatic Approaches to Studying DNA Methylation in Cancer

artículo científico publicado en 2022

Exploiting the complexity of the genome and transcriptome using pharmacogenomics towards personalized medicine

artículo científico publicado en 2011

Exploiting tumor vulnerabilities: epigenetics, cancer metabolism and the mTOR pathway in the era of personalized medicine

artículo científico publicado en 2013

Extraordinary Cancer Epigenomics: Thinking Outside the Classical Coding and Promoter Box.

artículo científico publicado en 2016

Fatty liver and fibrosis in glycine N-methyltransferase knockout mice is prevented by nicotinamide

artículo científico publicado en 2010

First Barcelona Conference on Epigenetics and Cancer

artículo científico publicado en 2014

Frequent hypermethylation of the DNA repair gene MGMT in long-term survivors of glioblastoma multiforme.

artículo científico publicado en 2006

Frequent inactivation of PTEN/MMAC1 in primary prostate cancer

article

Frequent loss of endothelin-3 (EDN3) expression due to epigenetic inactivation in human breast cancer

artículo científico publicado en 2009

GATA-4 and GATA-5 transcription factor genes and potential downstream antitumor target genes are epigenetically silenced in colorectal and gastric cancer

artículo científico publicado en 2003

Gene amplification of the histone methyltransferase SETDB1 contributes to human lung tumorigenesis

artículo científico publicado en 2013

Gene amplification-associated overexpression of the RNA editing enzyme ADAR1 enhances human lung tumorigenesis

artículo científico publicado en 2015

Gene amplification-associated overexpression of the RNA editing enzyme ADAR1 enhances human lung tumorigenesis

artículo científico publicado en 2016

Gene promoter hypermethylation in tumors and serum of head and neck cancer patients

article

Gene-Expression Profiles in Hereditary Breast Cancer

article

Generating mutations but providing chemosensitivity: the role of O6-methylguanine DNA methyltransferase in human cancer

artículo científico publicado en 2004

Generation and characterization of rat and mouse monoclonal antibodies specific for MeCP2 and their use in X-inactivation studies

artículo científico publicado en 2011

Genetic analysis of p38 MAP kinases in myogenesis: fundamental role of p38alpha in abrogating myoblast proliferation

artículo científico publicado en 2007

Genetic and epigenetic profile of sporadic pheochromocytomas

artículo científico publicado en 2004

Genetic and epigenetic screening for gene alterations of the chromatin-remodeling factor, SMARCA4/BRG1, in lung tumors.

artículo científico publicado en 2004

Genetic syndromes caused by mutations in epigenetic genes

artículo científico publicado en 2013

Genetic unmasking of an epigenetically silenced microRNA in human cancer cells

artículo científico publicado en 2007

Genetic unmasking of epigenetically silenced tumor suppressor genes in colon cancer cells deficient in DNA methyltransferases

artículo científico publicado en 2003

Genetic variants in epigenetic genes and breast cancer risk.

artículo científico publicado en 2006

Genetics and epigenetics of leukemia and lymphoma: from knowledge to applications, meeting report of the Josep Carreras Leukaemia Research Institute

artículo científico publicado en 2020

Genome-Wide DNA Methylation Analysis Identifies Novel Hypomethylated Non-Pericentromeric Genes with Potential Clinical Implications in ICF Syndrome

artículo científico publicado en 2015

Genome-wide DNA methylation profiling predicts relapse in childhood B-cell acute lymphoblastic leukaemia

artículo científico publicado en 2012

Genome-wide analysis of DNA methylation differences in muscle and fat from monozygotic twins discordant for type 2 diabetes

artículo científico publicado en 2012

Genome-wide and gene-specific epigenomic platforms for hepatocellular carcinoma biomarker development trials

artículo científico publicado en 2014

Genome-wide parent-of-origin DNA methylation analysis reveals the intricacies of human imprinting and suggests a germline methylation-independent mechanism of establishment

artículo científico publicado en 2014

Genome-wide profiling of p53-regulated enhancer RNAs uncovers a subset of enhancers controlled by a lncRNA.

artículo científico publicado en 2015

Genomic DNA hypomethylation as a biomarker for bladder cancer susceptibility in the Spanish Bladder Cancer Study: a case-control study

artículo científico publicado en 2008

Genomic and Molecular Screenings Identify Different Mechanisms for Acquired Resistance to MET Inhibitors in Lung Cancer Cells

artículo científico publicado en 2017

Genomic p16 abnormalities in the progression of chronic myeloid leukemia into blast crisis

artículo científico publicado en 2003

Germ line polymorphisms in cytochrome-P450 1A1 (C4887 CYP1A1) and methylenetetrahydrofolate reductase (MTHFR) genes and endometrial cancer susceptibility

article

Germ-line variants in methyl-group metabolism genes and susceptibility to DNA methylation in normal tissues and human primary tumors.

artículo científico publicado en 2002

German-Catalan workshop on epigenetics and cancer

artículo científico publicado en 2013

Germline missense pathogenic variants in the BRCA1 BRCT domain, p.Gly1706Glu and p.Ala1708Glu, increase cellular sensitivity to PARP inhibitor olaparib by a dominant negative effect.

artículo científico publicado en 2016

Germline mutations in the spindle assembly checkpoint genes BUB1 and BUB3 are infrequent in familial colorectal cancer and polyposis

artículo científico publicado en 2018

Global DNA methylation: a common early event in oral cancer cases with exposure to environmental carcinogens or viral agents.

artículo científico publicado en 2009

Global Impairment of Immediate-Early Genes Expression in Rett Syndrome Models and Patients Linked to Myelination Defects

artículo científico publicado en 2023

Global epigenomic reconfiguration during mammalian brain development

artículo científico publicado en 2013

H3K4me1 marks DNA regions hypomethylated during aging in human stem and differentiated cells

artículo científico publicado en 2014

Head-to-head antisense transcription and R-loop formation promotes transcriptional activation

artículo científico publicado en 2015

Hematoma subgaleal espontáneo como manifestación de una alteración de la función plaquetaria

Heterozygous disruption of Hic1 predisposes mice to a gender-dependent spectrum of malignant tumors

artículo científico publicado en 2003

High rate ofMDR-1 and heterogeneous pattern ofMRP expression without gene amplification in endometrial cancer

article

High-performance capillary electrophoretic method for the quantification of 5-methyl 2'-deoxycytidine in genomic DNA: application to plant, animal and human cancer tissues

artículo científico publicado en 2002

Higher prevalence of cerebral white matter hyperintensities in homozygous APOE-ɛ4 allele carriers aged 45-75: Results from the ALFA study.

artículo científico publicado en 2017

Histone H1 depletion triggers an interferon response in cancer cells via activation of heterochromatic repeats

artículo científico publicado en 2017

Histone H3 and H4 modification profiles in a Rett syndrome mouse model.

artículo científico publicado en 2006

Histone deacetylase inhibitors: understanding a new wave of anticancer agents

artículo científico publicado en 2004

Hot topics in epigenetic mechanisms of aging: 2011.

artículo científico

How epigenetics can explain human metastasis: a new role for microRNAs

artículo científico publicado en 2009

How epigenetics integrates nuclear functions. Workshop on epigenetics and chromatin: transcriptional regulation and beyond

artículo científico publicado en 2005

Human DNA methylomes of neurodegenerative diseases show common epigenomic patterns.

artículo científico publicado en 2016

Human DNA methyltransferase 1 is required for maintenance of the histone H3 modification pattern

artículo científico publicado en 2004

Human native lipoprotein-induced de novo DNA methylation is associated with repression of inflammatory genes in THP-1 macrophages

artículo científico publicado en 2011

Hypermethylation of a small CpGuanine-rich region correlates with loss of activator protein-2alpha expression during progression of breast cancer

artículo científico publicado en 2004

Hypermethylation of the DNA repair gene O(6)-methylguanine DNA methyltransferase and survival of patients with diffuse large B-cell lymphoma

artículo científico publicado en 2002

Hypermethylation of the alternative AWT1 promoter in hematological malignancies is a highly specific marker for acute myeloid leukemias despite high expression levels.

artículo científico publicado en 2014

Hypermethylation of the hMLH1 gene promoter in human gastric cancers with microsatellite instability

article

Hypermethylation of the hMLH1 gene promoter is associated with microsatellite instability in early human gastric neoplasia.

artículo científico publicado en 2001

Hypermethylation of the proapoptotic gene TMS1/ASC: prognostic importance in glioblastoma multiforme

artículo científico publicado en 2006

Hypermethylation-associated Inactivation of the Cellular Retinol-Binding-Protein 1 Gene in Human Cancer.

artículo científico publicado en 2002

Hypermethylation-associated inactivation of p14(ARF) is independent of p16(INK4a) methylation and p53 mutational status

artículo científico publicado en 2000

IDIBELL cancer conference on metastasis and angiogenesis

artículo científico publicado en 2011

IGF2 Is Up-regulated by Epigenetic Mechanisms in Hepatocellular Carcinomas and Is an Actionable Oncogene Product in Experimental Models

artículo científico publicado en 2016

IL-4 orchestrates STAT6-mediated DNA demethylation leading to dendritic cell differentiation

artículo científico publicado en 2016

Identification of (1H)-pyrroles as histone deacetylase inhibitors with antitumoral activity.

artículo científico publicado en 2009

Identification of DNA hypermethylation of SOX9 in association with bladder cancer progression using CpG microarrays

artículo científico publicado en 2007

Identification of HERC5 and its potential role in NSCLC progression

artículo científico publicado en 2014

Identification of PMF1 methylation in association with bladder cancer progression

artículo científico publicado en 2008

Identification of a mononucleotide repeat as a major target for mitochondrial DNA alterations in human tumors

scientific article published on 01 October 2001

Identification of an Immune-specific Class of Hepatocellular Carcinoma, Based on Molecular Features

artículo científico publicado en 2017

Identification of an episignature of human colorectal cancer associated with obesity by genome-wide DNA methylation analysis.

artículo científico publicado en 2018

Identification of inflammatory mediators in patients with Crohn's disease unresponsive to anti-TNFα therapy

artículo científico publicado en 2014

Identification of tri- and tetracyclic pyrimidinediones as sirtuin inhibitors

artículo científico publicado en 2010

Immunohistochemical classification of non-BRCA1/2 tumors identifies different groups that demonstrate the heterogeneity of BRCAX families

artículo científico publicado en 2007

Impaired DICER1 function promotes stemness and metastasis in colon cancer.

artículo científico publicado en 2013

Impaired in vivo binding of MeCP2 to chromatin in the absence of its DNA methyl-binding domain

artículo científico publicado en 2013

Impaired recruitment of the histone methyltransferase DOT1L contributes to the incomplete reactivation of tumor suppressor genes upon DNA demethylation

artículo científico publicado en 2009

Improvement of the Rett syndrome phenotype in a MeCP2 mouse model upon treatment with levodopa and a dopa-decarboxylase inhibitor

artículo científico publicado en 2014

In vivo analysis of DNA methylation patterns recognized by specific proteins: coupling CHIP and bisulfite analysis

artículo científico publicado en 2004

In vivo conditional deletion of HDAC7 reveals its requirement to establish proper B lymphocyte identity and development.

artículo científico publicado en 2016

Inactivation of LKB1/STK11 is a common event in adenocarcinomas of the lung

artículo científico publicado en 2002

Inactivation of glutathione S-transferase P1 gene by promoter hypermethylation in human neoplasia.

artículo científico publicado en 1998

Inactivation of the DNA repair gene O6-methylguanine-DNA methyltransferase by promoter hypermethylation is a common event in primary human neoplasia

article

Inactivation of the DNA repair gene O6-methylguanine-DNA methyltransferase by promoter hypermethylation is associated with G to A mutations in K-ras in colorectal tumorigenesis

article

Inactivation of the DNA-repair gene MGMT and the clinical response of gliomas to alkylating agents

artículo científico publicado en 2000

Inactivation of the apoptosis effector Apaf-1 in malignant melanoma

artículo científico publicado en 2001

Inactivation of the lamin A/C gene by CpG island promoter hypermethylation in hematologic malignancies, and its association with poor survival in nodal diffuse large B-cell lymphoma.

artículo científico publicado en 2005

Inactivation of the tissue inhibitor of metalloproteinases-2 gene by promoter hypermethylation in lymphoid malignancies

artículo científico publicado en 2005

Increased loss of chromosome 9p21 but not p16 inactivation in primary non-small cell lung cancer from smokers

artículo científico publicado en 2001

Infinium DNA Methylation Microarrays on Formalin-Fixed, Paraffin-Embedded Samples.

artículo científico publicado en 2018

Insights from the genetic and transcriptional characterization of a cancer of unknown primary (CUP)

scientific article published on 17 June 2020

Integrating gene expression and epidemiological data for the discovery of genetic interactions associated with cancer risk

artículo científico publicado en 2013

Intronic RNAs mediate EZH2 regulation of epigenetic targets

artículo científico publicado en 2012

Journal club: epigenetic profiling to classify cancer of unknown primary - Authors' reply.

artículo científico publicado en 2017

K-ras and p16 aberrations confer poor prognosis in human colorectal cancer

KAT6B Is a Tumor Suppressor Histone H3 Lysine 23 Acetyltransferase Undergoing Genomic Loss in Small Cell Lung Cancer

artículo científico publicado en 2015

Lack of methylthioadenosine phosphorylase expression in mantle cell lymphoma is associated with shorter survival: implications for a potential targeted therapy

artículo científico publicado en 2006

Late Crohn's disease patients present an increase in peripheral Th17 cells and cytokine production compared with early patients.

artículo científico publicado en 2009

Linkage of DNA Methylation Quantitative Trait Loci to Human Cancer Risk

Long-range epigenetic silencing associates with deregulation of Ikaros targets in colorectal cancer cells

artículo científico publicado en 2011

Loss of E-cadherin mediated cell-cell adhesion as an early trigger of apoptosis induced by photodynamic treatment

artículo científico publicado en 2005

Loss of acetylation at Lys16 and trimethylation at Lys20 of histone H4 is a common hallmark of human cancer

artículo científico publicado en 2005

Loss of chromosome arms 3p and 9p and inactivation ofP16INK4a in normal epithelium of patients with primary lung cancer

article

Loss of heterozygosity analysis at theBRCAloci in tumor samples from patients with familial breast cancer

article

Loss of the glycine N-methyltransferase gene leads to steatosis and hepatocellular carcinoma in mice

artículo científico publicado en 2008

Low-level microsatellite instability in most colorectal carcinomas

scientific article published on 01 February 2002

Lung cancer epigenetics: From knowledge to applications

artículo científico publicado en 2017

Lurbinectedin (PM01183), a new DNA minor groove binder, inhibits growth of orthotopic primary graft of cisplatin-resistant epithelial ovarian cancer

artículo científico publicado en 2012

Lymphangioleiomyomatosis Biomarkers Linked to Lung Metastatic Potential and Cell Stemness

artículo científico publicado en 2015

MGMT hypermethylation: a prognostic foe, a predictive friend

artículo científico publicado en 2007

MLH1 promoter hypermethylation is associated with the microsatellite instability phenotype in sporadic endometrial carcinomas

artículo científico publicado en 1998

Mammalian HP1 Isoforms Have Specific Roles in Heterochromatin Structure and Organization

artículo científico publicado en 2017

MeCP2: the long trip from a chromatin protein to neurological disorders

artículo científico publicado en 2014

Mechanisms of Therapy Resistance in Patient-Derived Xenograft Models of BRCA1-Deficient Breast Cancer

artículo científico publicado en 2016

Mecp2-null mice provide new neuronal targets for Rett syndrome.

artículo científico publicado en 2008

Merkel cell carcinoma of the vulva

artículo científico publicado en 1997

Metallothionein 1E is methylated in malignant melanoma and increases sensitivity to cisplatin-induced apoptosis

article

Metallothionein 1E is methylated in malignant melanoma and increases sensitivity to cisplatin-induced apoptosis.

artículo científico publicado en 2010

Metformin pharmacogenomics: a genome-wide association study to identify genetic and epigenetic biomarkers involved in metformin anticancer response using human lymphoblastoid cell lines

artículo científico publicado en 2016

MethCORR modelling of methylomes from formalin-fixed paraffin-embedded tissue enables characterization and prognostication of colorectal cancer

artículo científico publicado en 2020

Methyl-CpG binding proteins identify novel sites of epigenetic inactivation in human cancer.

artículo científico publicado en 2003

Methyl-CpG-binding proteins in cancer: blaming the DNA methylation messenger

artículo científico publicado en 2005

Methyl-DNA immunoprecipitation (MeDIP): hunting down the DNA methylome.

artículo científico publicado en 2008

Methylation of p16(INK4a) promoters occurs in vivo in histologically normal human mammary epithelia.

artículo científico publicado en 2003

Methylation regulation of Antiviral host factors, Interferon Stimulated Genes (ISGs) and T-cell responses associated with natural HIV control

scientific article published on 06 August 2020

Methylation status of the p15, p16 and MGMT promoter genes in primary cutaneous T-cell lymphomas

article

MiR-193b promoter methylation accurately detects prostate cancer in urine sediments and miR-34b/c or miR-129-2 promoter methylation define subsets of clinically aggressive tumors

scientific article published on 31 January 2017

MiR-204 silencing in intraepithelial to invasive cutaneous squamous cell carcinoma progression

artículo científico publicado en 2016

MiR-221 promotes stemness of breast cancer cells by targeting DNMT3b

artículo científico publicado en 2015

MiR-221/222 target the DNA methyltransferase MGMT in glioma cells

scientific journal article

MicroRNA expression profiling and DNA methylation signature for deregulated microRNA in cutaneous T-cell lymphoma

artículo científico publicado en 2014

MicroRNAs and Epigenetics

artículo científico publicado en 2017

MicroRNAs and cancer epigenetics: a macrorevolution

artículo científico publicado en 2010

Microsatellite instability in inflammatory bowel disease-associated neoplastic lesions is associated with hypermethylation and diminished expression of the DNA mismatch repair gene, hMLH1

article

Modeling lung cancer evolution and preclinical response by orthotopic mouse allografts

artículo científico publicado en 2014

Molecular Detection of Tumor Cells in Bronchoalveolar Lavage Fluid From Patients With Early Stage Lung Cancer

artículo científico publicado en 1999

Molecular analysis of a multistep lung cancer model induced by chronic inflammation reveals epigenetic regulation of p16 and activation of the DNA damage response pathway

artículo científico publicado en 2007

Molecular characterization of the immune class of hepatocellular carcinoma

Molecular detection of neoplastic cells in lymph nodes of metastatic colorectal cancer patients predicts recurrence

artículo científico publicado en 1999

Molecular detection of prostate cancer in urine by GSTP1 hypermethylation

artículo científico publicado en 2001

Molecular-Subtype-Specific Biomarkers Improve Prediction of Prognosis in Colorectal Cancer

artículo científico

Mouse models in epigenetics: insights in development and disease

artículo científico publicado en 2013

Moving Closer to a Prognostic DNA Methylation Signature in Colon Cancer: Figure 1

scientific article published on 01 March 2011

Multiple binding of methyl-CpG and polycomb proteins in long-term gene silencing events

artículo científico publicado en 2007

Multiple markers for melanoma progression regulated by DNA methylation: insights from transcriptomic studies

artículo científico publicado en 2005

Mutations in JMJD1C are involved in Rett syndrome and intellectual disability

artículo científico publicado en 2015

Mutator pathways unleashed by epigenetic silencing in human cancer

artículo científico publicado en 2007

N-BLR, a primate-specific non-coding transcript leads to colorectal cancer invasion and migration

artículo científico publicado en 2017

NID2 and HOXA9 promoter hypermethylation as biomarkers for prevention and early detection in oral cavity squamous cell carcinoma tissues and saliva.

artículo científico publicado en 2011

New insights into the biology and origin of mature aggressive B-cell lymphomas by combined epigenomic, genomic, and transcriptional profiling

artículo científico publicado en 2008

New therapeutic targets in cancer: the epigenetic connection

artículo científico publicado en 2006

Non-CpG island promoter hypomethylation and miR-149 regulate the expression of SRPX2 in colorectal cancer

artículo científico publicado en 2012

Normative data on angular vestibulo-ocular responses in the yaw axis measured using the video head impulse test.

artículo científico publicado en 2015

Notch signaling is essential for ventricular chamber development

artículo científico publicado en 2007

Notch1 Pathway Activation Results from the Epigenetic Abrogation of Notch-Related MicroRNAs in Mycosis Fungoides.

artículo científico publicado en 2015

Novel epigenetically deregulated genes in testicular cancer include homeobox genes and SCGB3A1 (HIN-1).

artículo científico publicado en 2006

Novel insights into DNA methylation features in spermatozoa: stability and peculiarities

artículo científico publicado en 2012

Novel methylation panel for the early detection of colorectal tumors in stool DNA.

artículo científico publicado en 2010

Novel methylation panel for the early detection of neoplasia in high-risk ulcerative colitis and Crohn's colitis patients.

artículo científico publicado en 2013

NuRD-dependent DNA methylation prevents ES cells from accessing a trophectoderm fate

artículo científico publicado en 2012

Obesity and menopause modify the epigenomic profile of breast cancer

artículo científico publicado en 2017

Oncometabolite Accumulation and Epithelial-to-Mesenchymal Transition: The Turn of Fumarate.

artículo científico publicado en 2016

Opening the treasure chest of miR-200s family members

artículo científico publicado en 2009

Opening up the DNA methylome of dementia

artículo científico publicado en 2017

Orthoxenografts of testicular germ cell tumors demonstrate genomic changes associated with cisplatin resistance and identify PDMP as a re-sensitizing agent.

artículo científico publicado en 2018

Oxidation of carboxyamidomethyl cysteine may add complexity to protein identification

artículo científico publicado en 2005

P0265 : IGF2 is an oncogenic driver in HCC and emerges as a potential target for therapies

PM20D1 is a quantitative trait locus associated with Alzheimer’s disease

scientific article published on 07 May 2018

Phase II study of temozolomide (TMZ) in metastatic colorectal cancer (mCRC) patients molecularly selected by MGMT promoter hypermethylation

Point mutation and homozygous deletion of PTEN/MMAC1 in primary bladder cancers

artículo científico publicado en 1998

Polyamines affect histamine synthesis during early stages of IL-3-induced bone marrow cell differentiation.

artículo científico publicado en 2009

Polychlorinated biphenyls affect histone modification pattern in early development of rats: a role for androgen receptor-dependent modulation?

article

Precision medicine based on epigenomics: the paradigm of carcinoma of unknown primary

artículo científico publicado en 2017

Prenatal antidepressant exposure associated with CYP2E1 DNA methylation change in neonates

artículo científico publicado en 2015

Primary intracranial spindle cell sarcoma with rhabdomyosarcoma-like features share a highly distinct methylation profile and DICER1 mutations.

artículo científico publicado en 2018

Procaine is a DNA-demethylating agent with growth-inhibitory effects in human cancer cells.

artículo científico publicado en 2003

Profiling aberrant DNA methylation in hematologic neoplasms: a view from the tip of the iceberg ⬇️

artículo científico publicado el 1 de octubre de 2003

Profiling epigenetic alterations in disease

artículo científico publicado en 2011

Profiling of oxBS-450K 5-hydroxymethylcytosine in human placenta and brain reveals enrichment at imprinted loci.

artículo científico publicado en 2017

Promoter CpG island hypermethylation of the DNA repair enzyme MGMT predicts clinical response to dacarbazine in a phase II study for metastatic colorectal cancer.

artículo científico publicado en 2013

Promoter DNA hypermethylation and gene repression in undifferentiated Arabidopsis cells

artículo científico publicado en 2008

Promoter hypermethylation and BRCA1 inactivation in sporadic breast and ovarian tumors

artículo científico publicado en 2000

Promoter hypermethylation leads to decreased APC mRNA expression in familial polyposis and sporadic colorectal tumours, but does not substitute for truncating mutations

artículo científico publicado en 2008

Promoter hypermethylation of the DNA repair gene O(6)-methylguanine-DNA methyltransferase is associated with the presence of G:C to A:T transition mutations in p53 in human colorectal tumorigenesis

artículo científico publicado en 2001

Promoter hypermethylation of the phosphatase DUSP22 mediates PKA-dependent TAU phosphorylation and CREB activation in Alzheimer's disease

artículo científico publicado en 2014

Proteins that bind methylated DNA and human cancer: reading the wrong words

artículo científico publicado en 2008

Publisher Correction: MethCORR modelling of methylomes from formalin-fixed paraffin-embedded tissue enables characterization and prognostication of colorectal cancer

scientific article published on 03 June 2020

Putative cis-regulatory drivers in colorectal cancer.

artículo científico publicado en 2014

Quantification of global DNA methylation by capillary electrophoresis and mass spectrometry

artículo científico publicado en 2009

RASSF2 hypermethylation is present and related to shorter survival in squamous cervical cancer.

artículo científico publicado en 2013

RETRACTED: A TARBP2 mutation in human cancer impairs microRNA processing and DICER1 function

artículo científico publicado en 2009

RNA-RNA interactions in gene regulation: the coding and noncoding players

artículo científico

Re-Expression of Fetal Igf2 as Epidriver and Target for Therapy in Hcc

Re: A DNA Repair Pathway-Focused Score for Prediction of Outcomes in Ovarian Cancer Treated with Platinum-Based Chemotherapy

Recruitment of CREB1 and histone deacetylase 2 (HDAC2) to the mouse Ltbp-1 promoter regulates its constitutive expression in a dioxin receptor-dependent manner

artículo científico publicado en 2008

Refinement of computational identification of somatic copy number alterations using DNA methylation microarrays illustrated in cancers of unknown primary

artículo científico publicado en 2022

Regulation of DNA methylation patterns by CK2-mediated phosphorylation of Dnmt3a.

artículo científico publicado en 2014

Regulation of SNAIL1 and E-cadherin function by DNMT1 in a DNA methylation-independent context

artículo científico publicado en 2011

Regulation of pri-miRNA Processing by a Long Noncoding RNA Transcribed from an Ultraconserved Region

scholarly article by Julia Liz published in July 2014

Release of Hypoacetylated and Trimethylated Histone H4 Is an Epigenetic Marker of Early Apoptosis

artículo científico publicado en 2006

Relevance of DNA methylation in the management of cancer

artículo científico publicado en 2003

Resistance to Taxanes in Triple-Negative Breast Cancer Associates with the Dynamics of a CD49f+ Tumor-Initiating Population

artículo científico publicado en 2017

Retraction: A TARBP2 mutation in human cancer impairs microRNA processing and DICER1 function

Rett Syndrome: The First Forty Years 1966-2006

artículo científico publicado en 2006

Role of the RB1 family in stabilizing histone methylation at constitutive heterochromatin

artículo científico publicado en 2005

Rolling the Dice to Discover the Role of DICER in Tumorigenesis

S-adenosylmethionine levels regulate the schwann cell DNA methylome.

artículo científico publicado en 2014

SIRT6-dependent cysteine monoubiquitination in the PRE-SET domain of Suv39h1 regulates the NF-κB pathway

artículo científico publicado en 2018

SOCS-1, a negative regulator of cytokine signaling, is frequently silenced by methylation in multiple myeloma

artículo científico publicado en 2002

Salermide, a Sirtuin inhibitor with a strong cancer-specific proapoptotic effect.

artículo científico publicado en 2008

Sarcoma classification by DNA methylation profiling

artículo científico publicado en 2021

Selective inhibition of microRNA accessibility by RBM38 is required for p53 activity

artículo científico publicado en 2011

Sensitization of retinoids and corticoids to epigenetic drugs in MYC-activated lung cancers by antitumor reprogramming.

artículo científico publicado en 2016

Silencing of Kruppel-like factor 2 by the histone methyltransferase EZH2 in human cancer.

artículo científico publicado en 2011

SirT7 auto-ADP-ribosylation regulates glucose starvation response through mH2A1

scientific article published on 24 July 2020

Sirtuin 1 regulation of developmental genes during differentiation of stem cells.

artículo científico publicado en 2010

Small molecule enoxacin is a cancer-specific growth inhibitor that acts by enhancing TAR RNA-binding protein 2-mediated microRNA processing

artículo científico publicado en 2011

Snail mediates E-cadherin repression by the recruitment of the Sin3A/histone deacetylase 1 (HDAC1)/HDAC2 complex

artículo científico publicado en 2004

SnapShot: The Human DNA Methylome in Health and Disease

article

Specific hypermethylation of LINE-1 elements during abnormal overgrowth and differentiation of human placenta

artículo científico publicado en 2006

Standardized approach for microsatellite instability detection in gastric carcinomas

artículo científico publicado en 2004

Stem Cell Technology for (Epi)genetic Brain Disorders.

artículo científico publicado en 2017

Stem cell-like transcriptional reprogramming mediates metastatic resistance to mTOR inhibition.

artículo científico publicado en 2016

Stepwise analysis of MIR9 loci identifies miR-9-5p to be involved in Oestrogen regulated pathways in breast cancer patients

artículo científico publicado en 2017

Study of breast cancer incidence in patients of lymphangioleiomyomatosis.

artículo científico publicado en 2016

Susceptibility to endometrial cancer: influence of allelism at p53, glutathione S-transferase (GSTM1 and GSTT1) and cytochrome P-450 (CYP1A1) loci

artículo científico publicado en 1997

TGF-β oncogenic pathway in HCC: PMEPA1 as a biomarker of treatment response

TRIM28 and Interacting KRAB-ZNFs Control Self-Renewal of Human Pluripotent Stem Cells through Epigenetic Repression of Pro-differentiation Genes

artículo científico publicado en 2017

Targeted Exome Sequencing of Krebs Cycle Genes Reveals Candidate Cancer-Predisposing Mutations in Pheochromocytomas and Paragangliomas.

artículo científico publicado en 2017

Targeting aberrant DNA methylation in mesenchymal stromal cells as a treatment for myeloma bone disease

artículo científico publicado en 2021

Targeting melanoma: unusual epigenetics reveals the dynamic rewiring of metastatic cells.

artículo científico publicado en 2015

Targeting the histone orthography of cancer: drugs for writers, erasers and readers

artículo científico publicado en 2014

The ADAMTS12 metalloprotease gene is epigenetically silenced in tumor cells and transcriptionally activated in the stroma during progression of colon cancer.

artículo científico publicado en 2009

The ALFA project: A research platform to identify early pathophysiological features of Alzheimer's disease

artículo científico publicado en 2016

The B cell transcription program mediates hypomethylation and overexpression of key genes in Epstein-Barr virus-associated proliferative conversion.

artículo científico publicado en 2013

The Breast Cancer Oncogene EMSY Represses Transcription of Antimetastatic microRNA miR-31.

artículo científico publicado en 2014

The Coming of Age of DNA Methylation in Medicine in the Genomics and Postgenomics Era

artículo científico publicado en 2002

The DEXLIFE study methods: identifying novel candidate biomarkers that predict progression to type 2 diabetes in high risk individuals.

artículo científico publicado en 2014

The DNA methylation drift of the atherosclerotic aorta increases with lesion progression

artículo científico publicado en 2015

The DNA methylation landscape of hematological malignancies: an update

artículo científico publicado en 2020

The DNA methylation landscape of human cancer organoids available at the American type culture collection

scientific article published on 12 May 2020

The DNA methylome of glioblastoma multiforme

artículo científico publicado en 2010

The Epigenomic Revolution in Breast Cancer: From Single-Gene to Genome-Wide Next-Generation Approaches

artículo científico publicado en 2017

The Epitranscriptome of Noncoding RNAs in Cancer.

artículo científico publicado en 2017

The Inescapable Influence of Noncoding RNAs in Cancer

artículo científico publicado en 2015

The NCI-60 Methylome and Its Integration into CellMiner

artículo científico publicado en 2016

The PDGFRβ-AKT pathway contributes to CDDP-acquired resistance in testicular germ cell tumors

artículo científico publicado en 2013

The PEG13-DMR and brain-specific enhancers dictate imprinted expression within the 8q24 intellectual disability risk locus

artículo científico publicado en 2014

The Polycomb group protein EZH2 directly controls DNA methylation

artículo científico publicado en 2006

The RNA-binding protein HuR regulates DNA methylation through stabilization of DNMT3b mRNA.

artículo científico publicado en 2009

The Wnt antagonist DICKKOPF-1 gene is induced by 1alpha,25-dihydroxyvitamin D3 associated to the differentiation of human colon cancer cells.

artículo científico publicado en 2007

The absence of p53 is critical for the induction of apoptosis by 5-aza-2'-deoxycytidine

artículo científico publicado en 2004

The activatory long non-coding RNA DBE-T reveals the epigenetic etiology of facioscapulohumeral muscular dystrophy

artículo científico publicado en 2012

The affinity of different MBD proteins for a specific methylated locus depends on their intrinsic binding properties

artículo científico publicado en 2003

The breast cancer oncogene EMSY represses transcription of antimetastatic microRNA miR-31.

artículo científico publicado en 2014

The chromatin remodeling factor CHD8 interacts with elongating RNA polymerase II and controls expression of the cyclin E2 gene

artículo científico publicado en 2009

The chromatin remodeller CHD8 is required for E2F-dependent transcription activation of S-phase genes

artículo científico publicado en 2013

The clinicopathological significance of K-RAS point mutation and gene amplification in endometrial cancer

article

The dioxin receptor is silenced by promoter hypermethylation in human acute lymphoblastic leukemia through inhibition of Sp1 binding.

artículo científico publicado en 2006

The dynamic DNA methylomes of double-stranded DNA viruses associated with human cancer

artículo científico publicado en 2009

The epigenetic basis of twin discordance in age-related diseases

artículo científico publicado en 2007

The epigenetic breakdown of cancer cells: from DNA methylation to histone modifications

artículo científico publicado en 2005

The epigenetic face of systemic lupus erythematosus

artículo científico publicado en 2006

The epigenetic landscape of Alu repeats delineates the structural and functional genomic architecture of colon cancer cells.

artículo científico publicado en 2016

The expression of CSRP2 encoding the LIM domain protein CRP2 is mediated by TGF-beta in smooth muscle and hepatic stellate cells

artículo científico publicado en 2006

The impact of MECP2 mutations in the expression patterns of Rett syndrome patients.

artículo científico publicado en 2004

The impact of chromatin in human cancer: linking DNA methylation to gene silencing

artículo científico publicado en 2002

The interplay between DNA methylation and sequence divergence in recent human evolution.

artículo científico publicado en 2015

The intervening domain from MeCP2 enhances the DNA affinity of the methyl binding domain and provides an independent DNA interaction site.

artículo científico publicado en 2017

The loss of NKX3.1 expression in testicular--and prostate--cancers is not caused by promoter hypermethylation

artículo científico publicado en 2005

The necessity of a human epigenome project

artículo científico publicado en 2006

The novel DNA methylation inhibitor zebularine is effective against the development of murine T-cell lymphoma

artículo científico publicado en 2005

The role of histone deacetylases (HDACs) in human cancer

scientific article published on 07 March 2007

The transcribed pseudogene RPSAP52 enhances the oncofetal HMGA2-IGF2BP2-RAS axis through LIN28B-dependent and independent let-7 inhibition

artículo científico publicado en 2019

The transcription factor Slug represses E-cadherin expression and induces epithelial to mesenchymal transitions: a comparison with Snail and E47 repressors

artículo científico publicado en 2003

The transcription factor Slug repressesE-cadherinexpression and induces epithelial to mesenchymal transitions: a comparison with Snail and E47 repressors

scientific article published in 2016

The transcriptional repressor HDAC7 promotes apoptosis and c-Myc downregulation in particular types of leukemia and lymphoma.

artículo científico publicado en 2015

Thyroid hormone stimulates phosphoglycerate mutase activity and isozyme transition in rat muscle tissues

artículo científico publicado en 1994

Toward understanding and exploiting tumor heterogeneity

artículo científico publicado en 2015

Towards defining the lymphoma methylome

artículo científico publicado en 2006

Towards the human cancer epigenome: a first draft of histone modifications

artículo científico publicado en 2005

Transcriptional analysis of the intestinal mucosa of patients with ulcerative colitis in remission reveals lasting epithelial cell alterations

artículo científico publicado en 2012

Transcriptional profiling of MCF7 breast cancer cells in response to 5-Fluorouracil: relationship with cell cycle changes and apoptosis, and identification of novel targets of p53.

artículo científico publicado en 2006

Transcriptional silencing of the p73 gene in acute lymphoblastic leukemia and Burkitt's lymphoma is associated with 5' CpG island methylation.

artículo científico publicado en 1999

Transcriptional targets of the chromatin-remodelling factor SMARCA4/BRG1 in lung cancer cells.

artículo científico publicado en 2005

Transcriptomic profiling of urine extracellular vesicles reveals alterations of CDH3 in prostate cancer.

artículo científico publicado en 2016

Transforming pathways unleashed by a HDAC2 mutation in human cancer.

artículo científico publicado en 2008

Tumor Cell-SpecificBRCA1andRASSF1AHypermethylation in Serum, Plasma, and Peritoneal Fluid from Ovarian Cancer Patients

Tumor MGMT promoter hypermethylation changes over time limit temozolomide efficacy in a phase II trial for metastatic colorectal cancer

artículo científico

Tumor-Related Molecular Mechanisms of Oxaliplatin Resistance

artículo científico publicado en 2015

Unique genomic profile of fibrolamellar hepatocellular carcinoma

artículo científico publicado en 2015

Unmasking of epigenetically silenced candidate tumor suppressor genes by removal of methyl-CpG-binding domain proteins

artículo científico publicado en 2008

Usefulness of Transcriptional Blood Biomarkers as a Non-invasive Surrogate Marker of Mucosal Healing and Endoscopic Response in Ulcerative Colitis

artículo científico publicado en 2017

VAV3 mediates resistance to breast cancer endocrine therapy.

artículo científico publicado en 2014

Validation of DNA methylation profiling in formalin-fixed paraffin-embedded samples using the Infinium HumanMethylation450 Microarray.

artículo científico publicado en 2014

Validation of a DNA methylation microarray for 450,000 CpG sites in the human genome

artículo científico publicado en 2011

Validation of a DNA methylation microarray for 850,000 CpG sites of the human genome enriched in enhancer sequences

artículo científico publicado en 2015

Variable maternal methylation overlapping the nc886/vtRNA2-1 locus is locked between hypermethylated repeats and is frequently altered in cancer.

artículo científico publicado en 2014

Viral epigenomes in human tumorigenesis.

scientific article published on 25 January 2010

WNT10B functional dualism: beta-catenin/Tcf-dependent growth promotion or independent suppression with deregulated expression in cancer

artículo científico publicado en 2007

Walking pathways with positive feedback loops reveal DNA methylation biomarkers of colorectal cancer

Whole exome sequencing of Rett syndrome-like patients reveals the mutational diversity of the clinical phenotype

artículo científico publicado en 2016

Whole genome grey and white matter DNA methylation profiles in dorsolateral prefrontal cortex.

artículo científico publicado en 2017

Whole-exome sequencing identifies MDH2 as a new familial paraganglioma gene.

artículo científico publicado en 2015

Whole-genome bisulfite DNA sequencing of a DNMT3B mutant patient

artículo científico publicado en 2012

Wnt signaling promoter hypermethylation distinguishes lung primary adenocarcinomas from colorectal metastasis to the lung.

artículo científico publicado en 2006

Writers, readers and erasers of RNA modifications in cancer

artículo científico publicado en 2020

[Introduction to molecular biology of endometrial cancer]

scientific article published on 01 June 1996

and activity of a new small-molecule inhibitor of HDAC6 in mantle cell lymphoma

scholarly article by Montserrat Pérez-Salvia et al published November 2018 in Haematologica

hMLH1 promoter hypermethylation is an early event in human endometrial tumorigenesis

artículo científico publicado en 1999

lncRNAs and microRNAs with a role in cancer development

artículo científico

p14ARF silencing by promoter hypermethylation mediates abnormal intracellular localization of MDM2.

artículo científico publicado en 2001

El secreto de la vida eterna. Todo lo que sabemos para vivir más y mejor

obra escrita por Manel Esteller

El secreto de la vida eterna. Todo lo que sabemos para vivir más y mejor

edición publicada en 2023 de la obra escrita por Manel Esteller

Hablemos de cáncer. Más de 50 respuestas a las principales dudas

edición publicada en 2018 de la obra escrita por Manel Esteller

Hablemos de cáncer. Más de 50 respuestas a las principales dudas

obra escrita por Manel Esteller

No soy mi ADN. El origen de las enfermedades y cómo prevenirlas

obra escrita por Manel Esteller

No soy mi ADN. El origen de las enfermedades y cómo prevenirlas

edición publicada en 2017 de la obra escrita por Manel Esteller

Lista de obras de Manel Esteller

109 A novel Werner Syndrome mutation: Pharmacological treatment by read-through of nonsense mutations and epigenetic therapies

31st Annual Meeting and Associated Programs of the Society for Immunotherapy of Cancer (SITC 2016): part one

5'-CpG island methylation of the LKB1/STK11 promoter and allelic loss at chromosome 19p13.3 in sporadic colorectal cancer

A Combined Epigenetic Therapy Equals the Efficacy of Conventional Chemotherapy in Refractory Advanced Non-Small Cell Lung Cancer

A Comprehensive DNA Methylation Profile of Epithelial-to-Mesenchymal Transition

A CpG island hypermethylation profile of primary colorectal carcinomas and colon cancer cell lines

A DERL3-associated defect in the degradation of SLC2A1 mediates the Warburg effect

A DNA methylation fingerprint of 1628 human samples

A DNA methylation map of human cancer at single base-pair resolution.

A DNA methylation-based definition of biologically distinct breast cancer subtypes

A Novel Epigenetic Signature for Early Diagnosis in Lung Cancer

A Prognostic DNA Methylation Signature for Stage I Non–Small-Cell Lung Cancer

A gene hypermethylation profile of human cancer

A genetic defect in exportin-5 traps precursor microRNAs in the nucleus of cancer cells

A landscape of pharmacogenomic interactions in cancer.

A microRNA DNA methylation signature for human cancer metastasis

A microarray-based DNA methylation study of glioblastoma multiforme

A mouse skin multistage carcinogenesis model reflects the aberrant DNA methylation patterns of human tumors

A multiplatform approach identifies miR-152-3p as a common epigenetically regulated onco-suppressor in prostate cancer targeting TMEM97.

A mutation in the POT1 gene is responsible for cardiac angiosarcoma in TP53-negative Li-Fraumeni-like families

A novel Werner Syndrome mutation: pharmacological treatment by read-through of nonsense mutations and epigenetic therapies

A precursor microRNA in a cancer cell nucleus: get me out of here!

A predictor based on the somatic genomic changes of the BRCA1/BRCA2 breast cancer tumors identifies the non-BRCA1/BRCA2 tumors with BRCA1 promoter hypermethylation

A profile of methyl-CpG binding domain protein occupancy of hypermethylated promoter CpG islands of tumor suppressor genes in human cancer

A role for RNAi in the selective correction of DNA methylation defects.

A role for methyl-CpG binding domain protein 2 in the modulation of the estrogen response of pS2/TFF1 gene

A systematic profile of DNA methylation in human cancer cell lines

A truncating mutation of HDAC2 in human cancers confers resistance to histone deacetylase inhibition

A two-gene epigenetic signature for the prediction of response to neoadjuvant chemotherapy in triple-negative breast cancer patients

Aberrant DNA methylation as a cancer-inducing mechanism

Aberrant DNA methylation in non-small cell lung cancer-associated fibroblasts

Aberrant DNA methylation profiles in the premature aging disorders Hutchinson-Gilford Progeria and Werner syndrome

Aberrant epigenetic landscape in cancer: how cellular identity goes awry

Aberrant epigenetic landscape in intellectual disability.

Aberrant patterns of DNA methylation, chromatin formation and gene expression in cancer

Aberrant promoter methylation of multiple genes throughout the clinico-pathologic spectrum of B-cell neoplasia.

Aberrant promoter methylation of the transcription factor genes PAX5 alpha and beta in human cancers.

Aberrant regulation of messenger RNA 3'-untranslated region in human cancer.

Abnormal PcG protein expression in Hodgkin's lymphoma. Relation with E2F6 and NFkappaB transcription factors.

Abnormalities of E- and P-cadherin and catenin (β-, γ-catenin, and p120ctn) expression in endometrial cancer and endometrial atypical hyperplasia

Abnormalities of the APC/beta-catenin pathway in endometrial cancer

Absence of Maternal Methylation in Biparental Hydatidiform Moles from Women with NLRP7 Maternal-Effect Mutations Reveals Widespread Placenta-Specific Imprinting.

Abstract 2130A: Epigenetic silencing of TGFβ1, BCL6, KILLIN and CTSZ is related to trastuzumab resistance in HER2-positive breast cancer models

Abstract 2763: DNA methylation profiling unveils TGF-β hyperresponse in tumor associated fibroblasts from lung cancer patients

Abstract 2770: DERL3 hypermethylation alters rhabdomyosarcoma cell metabolism

Abstract 3820: Epigenetic re-expression of fetal IGF2 as therapeutic target in hepatocellular carcinoma

Abstract 3883: Clonal evolution of a lethal prostate cancer: Integrated whole genome analysis case study

Abstract 432: Loss of MGMT promoter methylation and resistance to cisplatin in non-seminomatous germ cell tumors

Abstract 4734: miR-9-5p expression in breast cancer correlates with hormone receptor status and affects patients survival

Abstract 4784: Effect of epigenetic drugs on chromatin remodeling complexes disrupted in cancer

Abstract 5394: Initial results from TRANSCAN ERA-NET BREMIR project: MicroRNAs expression profiling for identification of breast cancer patients at high risk to develop distant metastases

Abstract 5483: Implications of the type ofBRCA1germline mutation in the treatment of patients with hereditary breast cancer

Abstract A40: Epigenomic profiling identifies NCRNAs as novel tumor suppressors in developmental tumors

Abstract IA19: Cancer epigenomics: From knowledge to applications

Abstract LB-155: Identification of a DNA methylation signature in liquid biopsy for early non-small cell lung cancer (NSCLC) diagnosis

Advances in the molecular genetics of endometrial cancer (Review).

Allele-specific histone lysine methylation marks regulatory regions at imprinted mouse genes

Alterations of the p16INK4a/Rb/cyclin-D1 pathway in vulvar carcinoma, vulvar intraepithelial neoplasia, and lichen sclerosus

Altered expression of adhesion molecules and epithelial-mesenchymal transition in silica-induced rat lung carcinogenesis

Altered expression of the imprinted transcription factor PLAGL1 deregulates a network of genes in the human IUGR placenta

An Adenine Code for DNA: A Second Life for N6-Methyladenine

An increase in MECP2 dosage impairs neural tube formation

An integrated epigenomic analysis for type 2 diabetes susceptibility loci in monozygotic twins

An integrated genomic analysis of anaplastic meningioma identifies prognostic molecular signatures

An integrated genomic analysis of anaplastic meningioma identifies prognostic molecular signatures

Analysis of adenomatous polyposis coli promoter hypermethylation in human cancer

Angiostatic activity of DNA methyltransferase inhibitors

Antitumor activity of a small-molecule inhibitor of the histone kinase Haspin

Arachidonic and oleic acid exert distinct effects on the DNA methylome.

Arbitrarily Primed-PCR and Related DNA Methylation Methodologies

Array-based DNA methylation profiling in acute myeloid leukaemia.

Array-based DNA-methylation profiling in sarcomas with small blue round cell histology provides valuable diagnostic information.

Assessing associations between the AURKA-HMMR-TPX2-TUBG1 functional module and breast cancer risk in BRCA1/2 mutation carriers

Associations between whole peripheral blood fatty acids and DNA methylation in humans

At the crossroad of lifespan, calorie restriction, chromatin and disease: meeting on sirtuins

B-cell leukemia transdifferentiation to macrophage involves reconfiguration of DNA methylation for long-range regulation

BCR-ABL1-induced expression of HSPA8 promotes cell survival in chronic myeloid leukaemia

BLUEPRINT to decode the epigenetic signature written in blood.

BMP Inhibition in Seminomas Initiates Acquisition of Pluripotency via NODAL Signaling Resulting in Reprogramming to an Embryonal Carcinoma