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Lista de obras de Massimo Libra

'Genetic profiling' and ovarian cancer therapy (review).

artículo científico publicado en 2011

A spindle cell variant of diffuse large B-cell lymphoma possesses genotypic and phenotypic markers characteristic of a germinal center B-cell origin

artículo científico publicado en 2006

Absence of human parvovirus B19 DNA in myoepithelial sialadenitis of primary Sjögren's syndrome

artículo científico publicado en 2002

Activation of the osteopontin/matrix metalloproteinase-9 pathway correlates with prostate cancer progression.

artículo científico publicado en 2008

Adherence to the Mediterranean Diet in Maltese Adults

artículo científico publicado en 2020

Adherence to the Mediterranean diet and nasopharyngeal cancer risk in Italy

artículo científico publicado en 2017

Advances in targeting signal transduction pathways

artículo científico publicado en 2012

Akt as a therapeutic target in cancer

artículo científico publicado en 2008

Alteration of Akt activity increases chemotherapeutic drug and hormonal resistance in breast cancer yet confers an achilles heel by sensitization to targeted therapy

artículo científico publicado en 2008

Analysis of TIMP-1 gene polymorphisms in Italian sclerodermic patients.

artículo científico publicado en 2006

Analysis of aberrant somatic hypermutation (SHM) in non-Hodgkin's lymphomas of patients with chronic HCV infection

artículo científico publicado en 2005

Analysis of the B-RafV600E mutation in cutaneous melanoma patients with occupational sun exposure

artículo científico publicado en 2014

Anticancer properties of the novel nitric oxide-donating compound (S,R)-3-phenyl-4,5-dihydro-5-isoxazole acetic acid-nitric oxide in vitro and in vivo.

artículo científico publicado en 2008

Association between Nutrient-Based Dietary Patterns and Bladder Cancer in Italy

scientific article published on 28 May 2020

Association between dietary inflammatory index and Hodgkin's lymphoma in an Italian case-control study

artículo científico publicado en 2018

Association of t(14;18) translocation with HCV infection in gastrointestinal MALT lymphomas.

artículo científico publicado en 2008

Associations of dietary carbohydrates, glycaemic index and glycaemic load with risk of bladder cancer: a case-control study.

artículo científico publicado en 2017

BRAF mutations in papillary thyroid carcinoma and emerging targeted therapies (review).

artículo científico publicado en 2012

Breast cancer risk in women treated with augmentation mammoplasty (review).

artículo científico

Cancer Management during COVID-19 Pandemic: Is Immune Checkpoint Inhibitors-Based Immunotherapy Harmful or Beneficial?

scientific article published on 10 August 2020

Characterization of human melanoma cell lines and melanocytes by proteome analysis

artículo científico publicado en 2011

Coffee, Tea, Cola, and Bladder Cancer Risk: Dose and Time Relationships.

artículo científico publicado en 2015

Combining chemo-, hormonal and targeted therapies to treat breast cancer (Review).

artículo científico publicado en 2008

Comparative study of rapamycin and temsirolimus demonstrates superimposable anti-tumour potency on prostate cancer cells.

artículo científico publicado en 2012

Contributions of the Raf/MEK/ERK, PI3K/PTEN/Akt/mTOR and Jak/STAT pathways to leukemia.

artículo científico publicado en 2008

Correction: Genetic Diversity of the KIR/HLA System and Susceptibility to Hepatitis C Virus-Related Diseases

artículo científico publicado en 2015

Correlation of the risk of breast cancer and disruption of the circadian rhythm (Review).

artículo científico

Critical Roles of EGFR Family Members in Breast Cancer and Breast Cancer Stem Cells: Targets for Therapy

artículo científico publicado en 2016

D1S80 VNTR locus genotypes in a population of Southeastern Sicily: Distribution and genetic disequilibrium

artículo científico publicado en 2004

Dehydroxymethylepoxyquinomicin inhibits expression and production of inflammatory mediators in interleukin-1beta-induced human chondrocytes

artículo científico publicado en 2010

Dehydroxymethylepoxyquinomicin, a novel nuclear factor-kappaB inhibitor, prevents inflammatory injury induced by interferon-gamma and histamine in NCTC 2544 keratinocytes

artículo científico publicado en 2010

Deregulation of the EGFR/PI3K/PTEN/Akt/mTORC1 pathway in breast cancer: possibilities for therapeutic intervention

artículo científico publicado en 2014

Diabetes mellitus and the risk of bladder cancer: an Italian case–control study

artículo científico publicado en 2015

Dietary Inflammatory Index and Risk of Bladder Cancer in a Large Italian Case-control Study

artículo científico publicado en 2016

Dietary inflammatory index and cancer risk in the elderly: A pooled-analysis of Italian case-control studies

scientific article published on 19 February 2019

Dietary inflammatory index and non-Hodgkin lymphoma risk in an Italian case-control study.

artículo científico publicado en 2017

Dietary intakes of carotenoids and other nutrients in the risk of nasopharyngeal carcinoma: a case-control study in Italy

artículo científico publicado en 2012

Dietary water intake and bladder cancer risk: An Italian case–control study

article

Different pediatric brain tumors are associated with different gene expression profiling.

artículo científico publicado en 2015

Differentiation between non-Hodgkin's lymphoma recurrence and second primary lymphoma by VDJ rearrangement analysis

article

Diverse roles of GSK-3: tumor promoter-tumor suppressor, target in cancer therapy

artículo científico

Dominant roles of the Raf/MEK/ERK pathway in cell cycle progression, prevention of apoptosis and sensitivity to chemotherapeutic drugs

artículo científico publicado en 2010

Droplet Digital PCR Analysis of Liquid Biopsy Samples Unveils the Diagnostic Role of hsa-miR-133a-3p and hsa-miR-375-3p in Oral Cancer

artículo científico publicado en 2020

Duration and intensity of tobacco smoking and the risk of papillary and non-papillary transitional cell carcinoma of the bladder

scientific article published on 26 June 2014

Ectopic NGAL expression can alter sensitivity of breast cancer cells to EGFR, Bcl-2, CaM-K inhibitors and the plant natural product berberine

artículo científico publicado en 2012

Effects of Ectopic Expression of NGAL on Doxorubicin Sensitivity

artículo científico publicado el 1 de octubre de 2012

Effects of mutations in Wnt/β-catenin, hedgehog, Notch and PI3K pathways on GSK-3 activity-Diverse effects on cell growth, metabolism and cancer

artículo científico

Effects of resveratrol, curcumin, berberine and other nutraceuticals on aging, cancer development, cancer stem cells and microRNAs

artículo científico publicado en 2017

Emerging MEK inhibitors.

artículo científico publicado en 2010

Emerging Raf inhibitors.

artículo científico publicado en 2009

Emerging targeted therapies for melanoma treatment (review)

artículo científico publicado en 2014

Enhancing therapeutic efficacy by targeting non-oncogene addicted cells with combinations of signal transduction inhibitors and chemotherapy

artículo científico publicado en 2010

Expression of cyclin-dependent kinase inhibitor p27(Kip1) in AIDS-related diffuse large-cell lymphomas is associated with Epstein-Barr virus-encoded latent membrane protein 1.

artículo científico publicado en 2002

Family history of cancer and the risk of bladder cancer: A case–control study from Italy

article

Functional Roles of Matrix Metalloproteinases and Their Inhibitors in Melanoma

artículo científico publicado en 2020

GSK-3 as potential target for therapeutic intervention in cancer

artículo científico publicado en 2014

Gene alterations in the PI3K/PTEN/AKT pathway as a mechanism of drug-resistance (review).

artículo científico

Genetic diversity of the KIR/HLA system and susceptibility to hepatitis C virus-related diseases.

artículo científico publicado en 2015

Genetic insights into the disease mechanisms of type II mixed cryoglobulinemia induced by hepatitis C virus.

artículo científico publicado en 2007

HCV-associated B cell clonalities in the liver do not carry the t(14;18) chromosomal translocation.

artículo científico publicado en 2005

HLA DR-DQ combination associated with the increased risk of developing human HCV positive non-Hodgkin's lymphoma is related to the type II mixed cryoglobulinemia

artículo científico publicado en 2009

Hepatitis B and C viruses and risk of non-Hodgkin lymphoma: a case-control study in Italy

artículo científico publicado en 2016

IL-6-174 G > C and MMP-9-1562 C > T polymorphisms are associated with increased risk of deep vein thrombosis in cancer patients.

artículo científico publicado en 2013

Identification of Modulated MicroRNAs Associated with Breast Cancer, Diet, and Physical Activity

scientific article published on 08 September 2020

Improved outcome with multimodal treatment and imatinib rechallenge in advanced GIST

artículo científico publicado en 2014

In vitro inhibition of enterobacteria-reactive CD4+CD25- T cells and suppression of immunoinflammatory colitis in mice by the novel immunomodulatory agent VGX-1027.

artículo científico publicado en 2008

Increased Levels of NF-kB-Dependent Markers in Cancer-Associated Deep Venous Thrombosis.

artículo científico publicado en 2015

Increased Risk of Nasopharyngeal Carcinoma with Increasing Levels of Diet-Associated Inflammation in an Italian Case-Control Study

artículo científico publicado en 2016

Induction of caspase-independent apoptotic-like cell death of mouse mammary tumor TA3Ha cells in vitro and reduction of their lethality in vivo by the novel chemotherapeutic agent GIT-27NO.

artículo científico publicado en 2010

Involvement of Akt and mTOR in chemotherapeutic- and hormonal-based drug resistance and response to radiation in breast cancer cells

artículo científico publicado en 2011

Involvement of Akt-1 and mTOR in sensitivity of breast cancer to targeted therapy

artículo científico publicado en 2011

Involvement of p53 and Raf/MEK/ERK pathways in hematopoietic drug resistance

artículo científico publicado en 2008

Low frequency of bcl-2 rearrangement in HCV-associated non-Hodgkin's lymphoma tissue

artículo científico publicado en 2003

Malignant melanoma in elderly patients: biological, surgical and medical issues.

artículo científico

Mediterranean Diet and Bladder Cancer Risk in Italy

article

Metabolic disorders and the risk of nasopharyngeal carcinoma: a case-control study in Italy.

artículo científico publicado en 2016

Metabolic syndrome and the risk of urothelial carcinoma of the bladder: a case-control study

artículo científico publicado en 2015

Modulation of YY1 and p53 expression by transforming growth factor-β3 in prostate cell lines

artículo científico publicado en 2011

Molecular analysis of the APC gene in Sicilian patients with familial adenomatous polyposis (F.A.P.).

artículo científico publicado en 2014

Molecular screening in Sicilian families with hereditary non-poliposis colorectal cancer (H.N.P.C.C.) syndrome: identification of a novel mutation in MSH2 gene.

artículo científico publicado en 2014

Multifaceted roles of GSK-3 and Wnt/β-catenin in hematopoiesis and leukemogenesis: opportunities for therapeutic intervention.

artículo científico publicado en 2014

Mutations and deregulation of Ras/Raf/MEK/ERK and PI3K/PTEN/Akt/mTOR cascades which alter therapy response

artículo científico publicado en 2012

New perspectives in HCV therapy: entry inhibitors.

artículo científico publicado en 2010

Novel nitric oxide-donating compound (S,R)-3-phenyl-4,5-dihydro-5-isoxazole acetic acid-nitric oxide (GIT-27NO) induces p53 mediated apoptosis in human A375 melanoma cells.

artículo científico publicado en 2008

PIK3CA mutations in human solid tumors: role in sensitivity to various therapeutic approaches

artículo científico publicado en 2009

Patient-Derived Tumor Organoids for Drug Repositioning in Cancer Care: A Promising Approach in the Era of Tailored Treatment

scientific article published on 04 December 2020

Patients with unrecognized peripheral arterial disease (PAD) assessed by ankle-brachial index (ABI) present a defined profile of proinflammatory markers compared to healthy subjects.

artículo científico publicado en 2012

Phase II study of the antiretroviral activity and safety of the glucocorticoid receptor antagonist mifepristone in HIV-1-infected patients

article

Plasma levels and zymographic activities of matrix metalloproteinases 2 and 9 in type II diabetics with peripheral arterial disease

artículo científico publicado en 2005

Polyphenol-Rich and Alcoholic Beverages and Metabolic Status in Adults Living in Sicily, Southern Italy

artículo científico publicado en 2021

Processed Meat and Risk of Renal Cell and Bladder Cancers

artículo científico publicado en 2018

Prognostic factors in soft tissue sarcomas: a study of 395 patients

artículo científico publicado en 2002

Raf kinase inhibitor protein (RKIP) and phospho-RKIP expression in melanomas

artículo científico publicado el 17 de abril de 2013

Ras/Raf/MEK/ERK and PI3K/PTEN/Akt/mTOR cascade inhibitors: how mutations can result in therapy resistance and how to overcome resistance

artículo científico publicado en 2012

Ras/Raf/MEK/ERK and PI3K/PTEN/Akt/mTOR inhibitors: rationale and importance to inhibiting these pathways in human health

artículo científico publicado en 2011

Red meat and cancer risk in a network of case-control studies focusing on cooking practices

artículo científico publicado en 2013

Regular aspirin use and nasopharyngeal cancer risk: A case-control study in Italy

article

Role of genetic polymorphisms and mutations in colorectal cancer therapy (Review).

artículo científico publicado en 2010

Role of the HLA class II: HCV-related disorders.

artículo científico publicado en 2007

Role of the Transcription Factor Yin Yang 1 and Its Selectively Identified Target Survivin in High-Grade B-Cells Non-Hodgkin Lymphomas: Potential Diagnostic and Therapeutic Targets

artículo científico publicado en 2020

Roles of EGFR and KRAS and their downstream signaling pathways in pancreatic cancer and pancreatic cancer stem cells

artículo científico

Roles of GSK-3 and microRNAs on epithelial mesenchymal transition and cancer stem cells

artículo científico publicado en 2016

Roles of NGAL and MMP-9 in the tumor microenvironment and sensitivity to targeted therapy

artículo científico

Roles of signaling pathways in drug resistance, cancer initiating cells and cancer progression and metastasis

artículo científico publicado en 2014

Roles of the RAF/MEK/ERK and PI3K/PTEN/AKT pathways in malignant transformation and drug resistance

artículo científico publicado en 2006

Roles of the Raf/MEK/ERK and PI3K/PTEN/Akt/mTOR pathways in controlling growth and sensitivity to therapy-implications for cancer and aging

artículo científico publicado en 2011

Roles of the Raf/MEK/ERK pathway in cell growth, malignant transformation and drug resistance

artículo científico publicado en 2007

Roles of the Ras/Raf/MEK/ERK pathway in leukemia therapy.

artículo científico publicado en 2011

Second primary lymphoma or recurrence: a dilemma solved by VDJ rearrangement analysis.

artículo científico publicado en 2004

Solid pseudopapillary tumour of the pancreas

artículo científico publicado en 2003

Stathmin regulates mutant p53 stability and transcriptional activity in ovarian cancer.

artículo científico publicado en 2013

Suppression of PTEN function increases breast cancer chemotherapeutic drug resistance while conferring sensitivity to mTOR inhibitors.

artículo científico publicado en 2008

Targeting GSK3 and Associated Signaling Pathways Involved in Cancer

scientific article published on 30 April 2020

Targeting breast cancer initiating cells: advances in breast cancer research and therapy

artículo científico publicado en 2014

Targeting prostate cancer based on signal transduction and cell cycle pathways.

artículo científico publicado en 2008

Targeting survival cascades induced by activation of Ras/Raf/MEK/ERK, PI3K/PTEN/Akt/mTOR and Jak/STAT pathways for effective leukemia therapy.

artículo científico publicado en 2008

Targeting the RAF/MEK/ERK, PI3K/AKT and p53 pathways in hematopoietic drug resistance.

artículo científico publicado en 2007

Targeting the cancer initiating cell: the ultimate target for cancer therapy.

artículo científico publicado en 2012

Targeting the leukemic stem cell: the Holy Grail of leukemia therapy

artículo científico publicado en 2008

Targeting the translational apparatus to improve leukemia therapy: roles of the PI3K/PTEN/Akt/mTOR pathway

artículo científico publicado en 2011

The Akt/mammalian target of rapamycin signal transduction pathway is activated in high-risk myelodysplastic syndromes and influences cell survival and proliferation

The Effect of Dietary Polyphenols on Vascular Health and Hypertension: Current Evidence and Mechanisms of Action

artículo científico publicado en 2022

The NO-modified HIV protease inhibitor as a valuable drug for hematological malignancies: Role of p70S6K.

artículo científico publicado en 2015

The Raf/MEK/ERK pathway can govern drug resistance, apoptosis and sensitivity to targeted therapy

artículo científico publicado en 2010

The antitumor properties of a nontoxic, nitric oxide-modified version of saquinavir are independent of Akt.

artículo científico publicado en 2009

The therapeutic potential of mTOR inhibitors in breast cancer

artículo científico publicado en 2016

The tumor microenvironment in hepatocellular carcinoma (review).

artículo científico

Therapeutic resistance resulting from mutations in Raf/MEK/ERK and PI3K/PTEN/Akt/mTOR signaling pathways.

artículo científico publicado en 2011

Tobacco smoking, alcohol drinking, and the risk of different histological types of nasopharyngeal cancer in a low-risk population

article published in 2011

Total Nut, Tree Nut, and Peanut Consumption and Metabolic Status in Southern Italian Adults

artículo científico publicado en 2021

Tumor microenvironment in diffuse large B-cell lymphoma: Matrixmetalloproteinases activation is mediated by osteopontin overexpression

artículo científico publicado en 2015

Understanding rituximab function and resistance: implications for tailored therapy.

scientific article published on January 2011

Unique Pattern of Overexpression of Raf-1 Kinase Inhibitory Protein in Its Inactivated Phosphorylated Form in Human Multiple Myeloma

artículo científico publicado en 2011

Uterine cervical carcinoma: role of matrix metalloproteinases (review).

artículo científico publicado en 2009

microRNAs and thyroid cancer: biological and clinical significance (Review).

artículo científico publicado en 2012