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Lista de obras de Anne White

-Prenylation of the indole ring improves the cytotoxicity of a short antagonist G analogue against small cell lung cancer

scientific article published on 17 February 2017

11-Dehydrocorticosterone Causes Metabolic Syndrome, Which Is Prevented when 11β-HSD1 Is Knocked Out in Livers of Male Mice

scientific article published on 05 July 2013

11β-Hydroxysteroid dehydrogenase type 1 (11β-HSD1) inhibitors still improve metabolic phenotype in male 11β-HSD1 knockout mice suggesting off-target mechanisms

artículo científico publicado en 2013

A missense mutation disrupting a dibasic prohormone processing site in pro-opiomelanocortin (POMC) increases susceptibility to early-onset obesity through a novel molecular mechanism

artículo científico publicado en 2002

A sensitive radioimmunoassay using a monoclonal antibody that is equipotent for ercalcitriol and calcitriol (1,25-dihydroxy vitamin D2 and D3)

artículo científico publicado en 1990

A study of 19-O-carboxymethyl ether and 19-hemisuccinate derivatives of testosterone: Their immunogenicity and use as iodinated radioligands for radioimmunoassay of testosterone

scientific article published in 1985

ACTH precursors: biological significance and clinical relevance

artículo científico publicado en 1998

Activity of the monocarboxylate transporter 1 inhibitor AZD3965 in small cell lung cancer

artículo científico publicado en 2013

Adrenocortical-pituitary hybrid tumor causing Cushing's syndrome

artículo científico publicado en 2001

Agouti-related protein (83-132) is a competitive antagonist at the human melanocortin-4 receptor: no evidence for differential interactions with pro-opiomelanocortin-derived ligands

artículo científico publicado en 2004

Agouti-related protein is posttranslationally cleaved by proprotein convertase 1 to generate agouti-related protein (AGRP)83-132: interaction between AGRP83-132 and melanocortin receptors cannot be influenced by syndecan-3

scientific journal article

Agouti-related protein: more than a melanocortin-4 receptor antagonist?

artículo científico publicado en 2005

Analysis of co-factor function in a glucocorticoid-resistant small cell carcinoma cell line.

artículo científico publicado en 2004

Analytical and clinical aspects of adrenocorticotrophin determination.

artículo científico publicado en 2003

Atorvastatin administration is associated with dose-related changes in IGF bioavailability.

artículo científico publicado en 2013

Biomarkers for small cell lung cancer: neuroendocrine, epithelial and circulating tumour cells

artículo científico

Brief report: impaired processing of prohormones associated with abnormalities of glucose homeostasis and adrenal function

artículo científico publicado en 1995

CDC7 protein kinase activity is required for mitosis and meiosis in Saccharomyces cerevisiae

artículo científico publicado el 1 de julio de 1991

Central Noradrenergic Lesion Impairs the Adrenocorticotrophin Response to Release of Endogenous Catecholamines

artículo científico publicado en 1992

Central actions of CRF on thermogenesis are mediated by pro-opiomelanocortin products

artículo científico publicado en 1991

Cerebrospinal fluid levels of beta endorphin in painful and painless diabetic polyneuropathy

artículo científico publicado en 1995

Cerebrospinal fluid levels of leptin, proopiomelanocortin, and agouti-related protein in human pregnancy: evidence for leptin resistance

artículo científico publicado en 2012

Characterisation of ACTH related peptides in ectopic Cushing's syndrome.

artículo científico publicado en 2003

Characterisation of monoclonal and polyclonal antibodies to 19-linked conjugates of testosterone with corresponding radioligands

artículo científico publicado en 1986

Characterisation of monoclonal antibodies to adrenocorticotrophin

artículo científico publicado en 1985

Characterisation of the CDC7 gene product of Saccharomyces cerevisiae as a protein kinase needed for the initiation of mitotic DNA synthesis

scientific article published on 01 December 1988

Clinical utility of plasma POMC and AgRP measurements in the differential diagnosis of ACTH-dependent Cushing's syndrome.

artículo científico publicado en 2014

Close relation of fasting insulin-like growth factor binding protein-1 (IGFBP-1) with glucose tolerance and cardiovascular risk in two populations.

artículo científico publicado en 2001

Constitutive synthesis of 1,25-dihydroxyvitamin D3 by a human small cell lung cancer cell line

artículo científico publicado en 1994

Continuous 24-hour leptin, proopiomelanocortin, and amino acid measurements in human cerebrospinal fluid: correlations with plasma leptin, soluble leptin receptor, and amino acid levels

artículo científico publicado en 2014

Correction: Loss of Glucocorticoid Receptor Expression by DNA Methylation Prevents Glucocorticoid Induced Apoptosis in Human Small Cell Lung Cancer Cells

artículo científico publicado en 2013

Cushing syndrome in a child due to pro-opiomelanocortin (POMC) secretion from a yolk sac tumor

artículo científico publicado en 2016

Cushing's Syndrome Due to Phaeochromocytoma Secreting the Precursors of Adrenocorticotropin

Cushing's syndrome due to phaeochromocytoma secreting the precursors of adrenocorticotropin

scientific article published on 01 December 2000

Cushing's syndrome in a 16 year old girl due to ectopic ACTH precursor production from a pancreatic tumour

artículo científico publicado en 2000

Deletion of Lkb1 in pro-opiomelanocortin neurons impairs peripheral glucose homeostasis in mice

artículo científico publicado en 2011

Development of adrenocorticotropin-(1-39) and precursor peptide secretory responses in the fetal sheep during the last third of gestation

artículo científico publicado en 1995

Developmental programming of hypothalamic neuronal circuits: impact on energy balance control

artículo científico publicado en 2015

Differential release of proopiomelanocortin-derived peptides from the human pituitary: evidence from a panel of two-site immunoradiometric assays

artículo científico publicado en 1994

Dissociation of steroid receptor coactivator 1 and nuclear receptor corepressor recruitment to the human glucocorticoid receptor by modification of the ligand-receptor interface: the role of tyrosine 735

artículo científico publicado en 2003

Do we all feel we succeed despite the system?

artículo científico publicado el 18 de junio de 2012

Effect of late hypothalamo-pituitary disconnection on the development of the HPA axis in the ovine fetus and the initiation of parturition

artículo científico publicado en 1994

Effect of variation in CYP11B1 and CYP11B2 on corticosteroid phenotype and hypothalamic-pituitary-adrenal axis activity in hypertensive and normotensive subjects

artículo científico publicado en 2007

Elevated Hypothalamic Glucocorticoid Levels Are Associated With Obesity and Hyperphagia in Male Mice.

artículo científico publicado en 2016

Epidemiology of the insulin-like growth factor system in three ethnic groups.

artículo científico publicado en 2001

Epigenetic changes in fetal hypothalamic energy regulating pathways are associated with maternal undernutrition and twinning

artículo científico publicado en 2012

Epigenetic changes in the hypothalamic pro-opiomelanocortin gene: A mechanism linking maternal undernutrition to obesity in the offspring?

artículo científico publicado el 3 de enero de 2011

Epigenetic changes in the hypothalamic proopiomelanocortin and glucocorticoid receptor genes in the ovine fetus after periconceptional undernutrition.

artículo científico publicado en 2010

Evaluation of CSF and plasma biomarkers of brain melanocortin activity in response to caloric restriction in humans.

artículo científico publicado en 2016

Glucocorticoid receptor over-expression promotes human small cell lung cancer apoptosis in vivo and thereby slows tumor growth

artículo científico publicado en 2010

Glucocorticoid receptor overexpression exerts an antisurvival effect on human small cell lung cancer cells.

artículo científico publicado en 2007

Glucocorticoid receptor-mediated apoptosis in small-cell lung cancer requires interaction with BCL2.

artículo científico publicado en 2013

Glucocorticoid receptor-mediated apoptosis: mechanisms of resistance in cancer cells

scientific article published on 20 May 2011

Growth and hormone profiling in children with congenital melanocytic naevi

artículo científico publicado en 2015

Hyperphagia and early-onset obesity due to a novel homozygous missense mutation in prohormone convertase 1/3.

artículo científico publicado en 2007

IGF-binding protein-1 inhibits IGF effects on adipocyte function: implications for insulin-like actions at the adipocyte

artículo científico publicado en 2002

IGF2 gene polymorphisms and IGF-II concentration are determinants of longitudinal weight trends in type 2 diabetes.

artículo científico publicado en 2013

Identification and functional analysis of SKA2 interaction with the glucocorticoid receptor

artículo científico publicado en 2008

Identification and functional characterization of Candida albicans CDC4.

artículo científico publicado en 2005

Impaired processing of proopiomelanocortin in corticotroph macroadenomas

artículo científico publicado en 1996

Insulin-like growth factor binding protein 5 and apoptosis in mammary epithelial cells

artículo científico publicado en 2003

Insulin-like growth factor-II and insulin-like growth factor binding protein-2 prospectively predict longitudinal elevation of HDL-cholesterol in type 2 diabetes

artículo científico publicado en 2014

Interaction of glucocorticoid receptor isoforms with transcription factors AP-1 and NF-kappaB: lack of effect of glucocorticoid receptor beta.

artículo científico publicado en 1999

International survey on high- and low-dose synacthen test and assessment of accuracy in preparing low-dose synacthen

artículo científico publicado en 2018

Irradiation Decreases the Neuroendocrine Biomarker Pro-Opiomelanocortin in Small Cell Lung Cancer Cells In Vitro and In Vivo

artículo científico publicado en 2016

Loss of glucocorticoid receptor expression by DNA methylation prevents glucocorticoid induced apoptosis in human small cell lung cancer cells

artículo científico publicado en 2011

Low circulating levels of insulin-like growth factor binding protein-1 (IGFBP-1) are closely associated with the presence of macrovascular disease and hypertension in type 2 diabetes.

artículo científico publicado en 2002

Low insulin-like growth factor-II levels predict weight gain in normal weight subjects with type 2 diabetes.

artículo científico publicado en 2006

Maternal overnutrition programs epigenetic changes in the regulatory regions of hypothalamic Pomc in the offspring of rats

scientific article published on 17 May 2018

Maternal undernutrition programs tissue-specific epigenetic changes in the glucocorticoid receptor in adult offspring

artículo científico publicado en 2013

Matrix metalloprotease-3 and -9 proteolyze insulin-like growth factor-binding protein-1.

artículo científico publicado en 2004

Measurement of insulin-like growth factor-II in human plasma using a specific monoclonal antibody-based two-site immunoradiometric assay.

artículo científico publicado en 1993

Mechanisms of activation of the pituitary-adrenal axis by tissue injury in the rat.

artículo científico publicado en 1994

Metabolic Abnormalities of Chronic High-Dose Glucocorticoids Are Not Mediated by Hypothalamic AgRP in Male Mice

artículo científico publicado en 2019

Metabolic pitfalls of CNS Cre-based technology

artículo científico publicado en 2013

Mice lacking pro-opiomelanocortin are sensitive to high-fat feeding but respond normally to the acute anorectic effects of peptide-YY(3-36).

scholarly article

Modification of plasma insulin-like growth factors and binding proteins during oral contraceptive use and the normal menstrual cycle.

artículo científico publicado en 1999

Monoclonal antibodies to testosterone: The effect of immunogen structure on specificity

artículo científico publicado en 1985

Monoclonal antibodies to the carboxy-terminal Ea sequence of pro-insulin-like growth factor-IA (proIGF-IA) recognize proIGF-IA secreted by IM9 B-lymphocytes

artículo científico publicado en 2001

Multiple hormone secretion by a human pancreatic glucagonoma in culture

article

Mutations in the amino-terminal region of proopiomelanocortin (POMC) in patients with early-onset obesity impair POMC sorting to the regulated secretory pathway

artículo científico publicado en 2008

Neuroendocrine and epithelial phenotypes in small-cell lung cancer: implications for metastasis and survival in patients

artículo científico publicado en 2013

Novel carbonic anhydrase IX-targeted therapy enhances the anti-tumour effects of cisplatin in small cell lung cancer.

artículo científico publicado en 2017

POMC: The Physiological Power of Hormone Processing

artículo científico publicado en 2018

Phosphorylated insulin-like growth factor binding protein 1 is increased in pregnant diabetic subjects

scientific article published on 01 February 1999

Processing of proglucagon to GLP-1 in pancreatic α-cells: is this a paracrine mechanism enabling GLP-1 to act on β-cells?

artículo científico publicado en 2011

Procorticotrophin-releasing hormone: endoproteolytic processing and differential release of its derived peptides within AtT20 cells.

artículo científico publicado en 1998

Progestins abrogate estrogen-induced changes in the insulin-like growth factor axis

artículo científico publicado en 2000

Prohormones: their clinical relevance.

artículo científico publicado en 1998

Proopiomelanocortin (POMC), the ACTH/melanocortin precursor, is secreted by human epidermal keratinocytes and melanocytes and stimulates melanogenesis.

artículo científico publicado en 2007

Proopiomelanocortin interference in the measurement of adrenocorticotrophic hormone: a United Kingdom National External Quality Assessment Service study.

artículo científico publicado en 2016

Proopiomelanocortin, agouti-related protein, and leptin in human cerebrospinal fluid: correlations with body weight and adiposity.

artículo científico publicado en 2015

Proopiomelanocortin-derived peptides in rat cerebrospinal fluid and hypothalamic extracts: evidence that secretion is regulated with respect to energy balance

artículo científico publicado en 2003

Purification and characterization of the insulin-like growth factor-binding protein-1 phosphoform found in normal plasma

scientific article published on 01 March 1997

Quantitative mass spectrometry for human melanocortin peptides in vitro and in vivo suggests prominent roles for β-MSH and desacetyl α-MSH in energy homeostasis

article

Rapid glucocorticoid receptor-mediated inhibition of hypothalamic-pituitary-adrenal ultradian activity in healthy males.

artículo científico publicado en 2010

Recurrent pituitary macroadenoma with increased plasma ACTH precursors that cross-react in a commonly used ACTH immunoassay.

artículo científico publicado en 2014

Reduced appetite and body mass index with delayed puberty in a mother and son: association with a rare novel sequence variant in the leptin gene

article

Reduced expression of the KATP channel subunit, Kir6.2, is associated with decreased expression of neuropeptide Y and agouti-related protein in the hypothalami of Zucker diabetic fatty rats

artículo científico publicado en 2007

Reduced insulin-like growth factor binding protein-1 (IGFBP-1) levels correlate with increased cardiovascular risk in non-insulin dependent diabetes mellitus (NIDDM)

scientific article published on 01 February 1996

Regulation of IGF bioavailability in pregnancy.

artículo científico publicado en 2001

Rifampicin: a glucocorticoid receptor ligand?

artículo científico publicado el 1 de octubre de 1998

Selection and optimisation of monoclonal antibodies for a two-site immunoradiometric assay for ACTH

artículo científico publicado en 1986

Selection of high-affinity and high-specificity monoclonal antibodies for 1α,25-dihydroxyvitamin D

artículo científico publicado en 1985

Small-intestinal dysfunction accompanies the complex endocrinopathy of human proprotein convertase 1 deficiency

artículo científico publicado en 2003

Targeting hypoxia in the treatment of small cell lung cancer

artículo científico publicado en 2014

The Role of the Placenta in Fetal Programming

The effect of the local anaesthetic, tetracaine, on the isoprenaline and prostaglandin E1 stimulation of cAMP in normal and malignant cell lines

artículo científico publicado en 1977

The influence of dietary intake on the insulin-like growth factor (IGF) system across three ethnic groups: a population-based study.

artículo científico publicado en 2003

The maternal insulin-like growth factor (IGF) and IGF-binding protein response to trisomic pregnancy during the first trimester: a possible diagnostic tool for trisomy 18 pregnancies

artículo científico publicado en 1997

The oestrogen receptor regulates NFκB and AP-1 activity in a cell-specific manner

artículo científico publicado en 1998

The phosphorylation pattern of insulin-like growth factor-binding protein-1 in normal plasma is different from that in amniotic fluid and changes during pregnancy

scientific article published on 01 December 1994

The synthesis of ACTH and related peptides by tumours

artículo científico publicado en 1990

UbcH7 interacts with the glucocorticoid receptor and mediates receptor autoregulation

artículo científico publicado en 2006

Will treating diabetes with 11β-HSD1 inhibitors affect the HPA axis?

artículo científico publicado en 2010

alpha 2-Macroglobulin: a new component in the insulin-like growth factor/insulin-like growth factor binding protein-1 axis.

artículo científico publicado en 2001