Lista de obras - Alan E Bilsland - Dominio Público Uruguay

A gene expression signature classifying telomerase and ALT immortalization reveals an hTERT regulatory network and suggests a mesenchymal stem cell origin for ALT.

artículo científico publicado en 2009

A multi-targeted approach to suppress tumor-promoting inflammation

artículo científico publicado en 2015

A mutation in a functional Sp1 binding site of the telomerase RNA gene (hTERC) promoter in a patient with Paroxysmal Nocturnal Haemoglobinuria

artículo científico publicado en 2004

Activation of telomerase rna gene promoter activity by NF-Y, Sp1, and the retinoblastoma protein and repression by Sp3.

artículo científico publicado en 2000

Broad targeting of angiogenesis for cancer prevention and therapy

artículo científico publicado en 2015

Broad targeting of resistance to apoptosis in cancer.

artículo científico publicado en 2015

Cancer cell senescence: a new frontier in drug development.

artículo científico

Drug insight: Cancer cell immortality-telomerase as a target for novel cancer gene therapies.

artículo científico publicado en 2004

Dynamic telomerase gene suppression via network effects of GSK3 inhibition

artículo científico publicado en 2009

Evasion of anti-growth signaling: A key step in tumorigenesis and potential target for treatment and prophylaxis by natural compounds.

artículo científico publicado en 2015

Genomic instability in human cancer: Molecular insights and opportunities for therapeutic attack and prevention through diet and nutrition.

artículo científico publicado en 2015

Hypoxic regulation of telomerase gene expression by transcriptional and post-transcriptional mechanisms

artículo científico publicado en 2006

Involvement of NF-Y and Sp1 binding sequences in basal transcription of the human telomerase RNA gene.

artículo científico publicado en 2003

Mathematical model of a telomerase transcriptional regulatory network developed by cell-based screening: analysis of inhibitor effects and telomerase expression mechanisms

artículo científico publicado en 2014

MicroRNA and senescence: the senectome, integration and distributed control

artículo científico publicado en 2013

Modulation of gene expression using zinc finger-based artificial transcription factors

artículo científico publicado en 2010

Modulation of telomerase promoter tumor selectivity in the context of oncolytic adenoviruses.

artículo científico publicado en 2007

Plasma N-acetyl-glucosaminidase in advanced gastro-intestinal adenocarcinoma correlates with age, stage and outcome

artículo científico publicado en 2015

Properties of a telomerase-specific Cre/Lox switch for transcriptionally targeted cancer gene therapy.

artículo científico publicado en 2005

Scoring of senescence signalling in multiple human tumour gene expression datasets, identification of a correlation between senescence score and drug toxicity in the NCI60 panel and a pro-inflammatory signature correlating with survival [...]

artículo científico publicado en 2010

Selective ablation of human cancer cells by telomerase-specific adenoviral suicide gene therapy vectors expressing bacterial nitroreductase

artículo científico publicado en 2003

Synthetic anticancer gene medicine exploits intrinsic antitumor activity of cationic vector to cure established tumors.

artículo científico publicado en 2005

TCEAL7 inhibition of c-Myc activity in alternative lengthening of telomeres regulates hTERT expression

artículo científico publicado en 2010

Targeting the telomere and shelterin complex for cancer therapy: current views and future perspectives.

scientific article published on February 2011

Telomerase-directed molecular therapeutics

artículo científico publicado en 2002

Telomerase-specific suicide gene therapy vectors expressing bacterial nitroreductase sensitize human cancer cells to the pro-drug CB1954.

artículo científico publicado en 2001

Therapeutic targeting of replicative immortality

artículo científico publicado en 2015

Tissue invasion and metastasis: Molecular, biological and clinical perspectives

artículo científico

Transcriptional repression of telomerase RNA gene expression by c-Jun-NH2-kinase and Sp1/Sp3.

artículo científico publicado en 2006

Virotherapy: cancer gene therapy at last?

artículo científico publicado en 2016

Lista de obras de Alan E Bilsland

A gene expression signature classifying telomerase and ALT immortalization reveals an hTERT regulatory network and suggests a mesenchymal stem cell origin for ALT.

A multi-targeted approach to suppress tumor-promoting inflammation

A mutation in a functional Sp1 binding site of the telomerase RNA gene (hTERC) promoter in a patient with Paroxysmal Nocturnal Haemoglobinuria

Activation of telomerase rna gene promoter activity by NF-Y, Sp1, and the retinoblastoma protein and repression by Sp3.

Broad targeting of angiogenesis for cancer prevention and therapy

Broad targeting of resistance to apoptosis in cancer.

Cancer cell senescence: a new frontier in drug development.

Drug insight: Cancer cell immortality-telomerase as a target for novel cancer gene therapies.

Dynamic telomerase gene suppression via network effects of GSK3 inhibition

Evasion of anti-growth signaling: A key step in tumorigenesis and potential target for treatment and prophylaxis by natural compounds.

Genomic instability in human cancer: Molecular insights and opportunities for therapeutic attack and prevention through diet and nutrition.

Hypoxic regulation of telomerase gene expression by transcriptional and post-transcriptional mechanisms

Involvement of NF-Y and Sp1 binding sequences in basal transcription of the human telomerase RNA gene.

Mathematical model of a telomerase transcriptional regulatory network developed by cell-based screening: analysis of inhibitor effects and telomerase expression mechanisms

MicroRNA and senescence: the senectome, integration and distributed control

Modulation of gene expression using zinc finger-based artificial transcription factors

Modulation of telomerase promoter tumor selectivity in the context of oncolytic adenoviruses.

Plasma N-acetyl-glucosaminidase in advanced gastro-intestinal adenocarcinoma correlates with age, stage and outcome

Properties of a telomerase-specific Cre/Lox switch for transcriptionally targeted cancer gene therapy.

Scoring of senescence signalling in multiple human tumour gene expression datasets, identification of a correlation between senescence score and drug toxicity in the NCI60 panel and a pro-inflammatory signature correlating with survival [...]

Selective ablation of human cancer cells by telomerase-specific adenoviral suicide gene therapy vectors expressing bacterial nitroreductase

Synthetic anticancer gene medicine exploits intrinsic antitumor activity of cationic vector to cure established tumors.

TCEAL7 inhibition of c-Myc activity in alternative lengthening of telomeres regulates hTERT expression

Targeting the telomere and shelterin complex for cancer therapy: current views and future perspectives.

Telomerase-directed molecular therapeutics

Telomerase-specific suicide gene therapy vectors expressing bacterial nitroreductase sensitize human cancer cells to the pro-drug CB1954.

Therapeutic targeting of replicative immortality

Tissue invasion and metastasis: Molecular, biological and clinical perspectives

Transcriptional repression of telomerase RNA gene expression by c-Jun-NH2-kinase and Sp1/Sp3.

Virotherapy: cancer gene therapy at last?