Lista de obras - Maurizio Parola - Dominio Público Uruguay

4-Hydroxynonenal as a selective pro-fibrogenic stimulus for activated human hepatic stellate cells

artículo científico publicado en 2004

Adipokines and redox signaling: impact on fatty liver disease

artículo científico publicado en 2011

Age-dependent changes in extracellular matrix turnover: An under evaluated issue in the approach to chronic liver diseases

artículo científico publicado en 2015

Alteration of Na+ homeostasis as a critical step in the development of irreversible hepatocyte injury after adenosine triphosphate depletion

artículo científico publicado en 1995

Angiogenesis and Fibrogenesis in Chronic Liver Diseases

artículo científico publicado en 2015

Beta-catenin triggers nuclear factor kappaB-dependent up-regulation of hepatocyte inducible nitric oxide synthase

artículo científico publicado en 2008

Beta-site APP cleaving enzyme up-regulation induced by 4-hydroxynonenal is mediated by stress-activated protein kinases pathways.

artículo científico publicado en 2005

Biochemical studies on bile duct epithelial cells isolated from rat liver

artículo científico publicado en 1990

Calcium receptors located in fibrotic septa: a new target to reduce portal pressure in liver cirrhosis

artículo científico publicado en 2013

Calcium-dependent diuretic system in preascitic liver cirrhosis

artículo científico publicado en 2010

Celecoxib inactivates epithelial-mesenchymal transition stimulated by hypoxia and/or epidermal growth factor in colon cancer cells

artículo científico publicado en 2011

Corrigendum to “Silibinin improves hepatic and myocardial injury in mice with nonalcoholic steatohepatitis” [Dig. Liver Dis. 44 (2012) 334–342]

scholarly article published in Digestive and Liver Disease

Curcumin limits the fibrogenic evolution of experimental steatohepatitis.

artículo científico publicado en 2009

Dehydroepiandrosterone modulates nuclear factor-kappaB activation in hippocampus of diabetic rats

scientific journal article

Detection of cytochrome P4503A (CYP3A) in human hepatic stellate cells.

artículo científico publicado en 1997

Dissection of the biphasic nature of hypoxia-induced motogenic action in bone marrow-derived human mesenchymal stem cells.

artículo científico publicado en 2011

Dose dependent and divergent effects of superoxide anion on cell death, proliferation, and migration of activated human hepatic stellate cells

artículo científico publicado en 2005

Dose-dependency of clonidine's effects in ascitic cirrhotic rats: comparison with α1-adrenergic agonist midodrine.

artículo científico publicado en 2015

ERK Pathway in Activated, Myofibroblast-Like, Hepatic Stellate Cells: A Critical Signaling Crossroad Sustaining Liver Fibrosis

artículo científico publicado en 2019

Effects of carbon tetrachloride on calcium homeostasis. A critical reconsideration

scientific article published on 01 August 1989

Endocellular polyamine availability modulates epithelial-to-mesenchymal transition and unfolded protein response in MDCK cells.

artículo científico publicado en 2010

Endogenous annexin A1 is a novel protective determinant in nonalcoholic steatohepatitis in mice.

artículo científico publicado en 2014

Expression of Cox-2 in human breast cancer cells as a critical determinant of epithelial-to-mesenchymal transition and invasiveness

artículo científico publicado en 2013

Expression of platelet-derived growth factor in newly formed cholangiocytes during experimental biliary fibrosis in rats

scientific article published on 01 July 1999

Fat-laden macrophages modulate lobular inflammation in nonalcoholic steatohepatitis (NASH).

artículo científico publicado en 2015

H2O2 and 4-hydroxynonenal mediate amyloid beta-induced neuronal apoptosis by activating JNKs and p38MAPK.

artículo científico publicado en 2003

Hepatic myofibroblasts and fibrogenic progression of chronic liver diseases

artículo científico

Hepatic progenitor cells express SerpinB3

artículo científico publicado en 2014

Hepatic wound repair

artículo científico publicado en 2009

Hepatocellular metabolism of 4-hydroxy-2,3-nonenal is impaired in conditions of chronic cholestasis

scientific article published on 01 September 1995

Human hepatic stellate cells express class I alcohol dehydrogenase and aldehyde dehydrogenase but not cytochrome P4502E1.

artículo científico publicado en 1998

Human mesenchymal stem cells as a two-edged sword in hepatic regenerative medicine: engraftment and hepatocyte differentiation versus profibrogenic potential

artículo científico publicado en 2007

Human-induced pluripotent stem cells as a source of hepatocyte-like cells: new kids on the block

artículo científico publicado en 2011

Hypoxia, angiogenesis and liver fibrogenesis in the progression of chronic liver diseases

artículo científico publicado en 2010

Induction of Procollagen Type I Gene Expression and Synthesis in Human Hepatic Stellate Cells by 4-Hydroxy-2,3-Nonenal and Other 4-Hydroxy-2,3-Alkenals Is Related to Their Molecular Structure

article

Inhibition of the high affinity Ca2(+)-ATPase activity in rat liver plasma membranes following carbon tetrachloride intoxication

artículo científico publicado en 1990

Interaction between 4-hydroxy-2,3-alkenals and the platelet-derived growth factor-beta receptor. Reduced tyrosine phosphorylation and downstream signaling in hepatic stellate cells

artículo científico publicado en 2000

Intracellular free iron and acidic pathways mediate TNF-induced death of rat hepatoma cells.

artículo científico publicado en 2005

Intracellular reactive oxygen species are required for directional migration of resident and bone marrow-derived hepatic pro-fibrogenic cells.

artículo científico publicado en 2010

Isolation and characterization of biliary epithelial cells from normal rat liver

artículo científico publicado en 1988

Lipid-induced toxicity stimulates hepatocytes to release angiogenic microparticles that require Vanin-1 for uptake by endothelial cells

artículo científico publicado en 2013

Liver AP-1 activation due to carbon tetrachloride is potentiated by 1,2-dibromoethane but is inhibited by alpha-tocopherol or gadolinium chloride

artículo científico publicado en 1999

Liver fibrogenic cells ⬇️

artículo científico publicado el 1 de abril de 2011

Liver/kidney microsomal antibody type 1 targets CYP2D6 on hepatocyte plasma membrane.

artículo científico publicado en 2000

Mammalian target of rapamycin mediates the angiogenic effects of leptin in human hepatic stellate cells

artículo científico publicado en 2011

Menadione and cumene hydroperoxide induced cytotoxicity in biliary epithelial cells isolated from rat liver

artículo científico publicado en 1990

Mitochondrial damage and its role in causing hepatocyte injury during stimulation of lipid peroxidation by iron nitriloacetate

artículo científico publicado en 1992

Modulation of hepatic fibrogenesis by antioxidants.

artículo científico publicado en 1993

Multiple signaling events in amyloid beta-induced, oxidative stress-dependent neuronal apoptosis

artículo científico publicado en 2003

Myofibroblast - like cells and liver fibrogenesis: Emerging concepts in a rapidly moving scenario.

artículo científico publicado en 2007

Neutral endopeptidase (EC 3.4.24.11) in cirrhotic liver: a new target to treat portal hypertension?

artículo científico publicado en 2005

Of FACT complex and oxidative stress response: a KEAP1/NRF2-dependent novel mechanism sustaining hepatocellular carcinoma progression

scientific article published on 15 October 2019

On the role of lipid peroxidation in the pathogenesis of liver damage induced by long-standing cholestasis

scientific article published on 01 January 1996

Overexpression of Bcl-2 by activated human hepatic stellate cells: resistance to apoptosis as a mechanism of progressive hepatic fibrogenesis in humans.

artículo científico publicado en 2006

Oxidative damage and fibrogenesis

artículo científico publicado en 1997

Oxidative stress-related molecules and liver fibrosis

artículo científico publicado en 2001

Pathogenesis of solute-free water retention in experimental ascitic cirrhosis: is vasopressin the only culprit?

artículo científico publicado en 2015

Phosphatidylinositol 3-kinase is required for platelet-derived growth factor's actions on hepatic stellate cells

artículo científico publicado en 1997

Prevention of severe toxic liver injury and oxidative stress in MCP-1-deficient mice

article

Redox mechanisms in hepatic chronic wound healing and fibrogenesis

artículo científico publicado en 2008

Redox mechanisms switch on hypoxia-dependent epithelial-mesenchymal transition in cancer cells

artículo científico publicado en 2008

Resistin as an intrahepatic cytokine: overexpression during chronic injury and induction of proinflammatory actions in hepatic stellate cells

artículo científico publicado en 2006

SERPINB3 induces epithelial-mesenchymal transition

artículo científico publicado en 2010

SerpinB3 Differently Up-Regulates Hypoxia Inducible Factors -1α and -2α in Hepatocellular Carcinoma: Mechanisms Revealing Novel Potential Therapeutic Targets

scientific article published on 04 December 2019

SerpinB3 and Yap Interplay Increases Myc Oncogenic Activity.

artículo científico publicado en 2015

Silibinin improves hepatic and myocardial injury in mice with nonalcoholic steatohepatitis.

artículo científico publicado en 2011

Stem and progenitor cells in liver regeneration and repair.

scientific article published on February 2011

Stem cells in liver failure

artículo científico

Stimulation of lipid peroxidation increases the intracellular calcium content of isolated hepatocytes

scientific article published on 01 February 1991

Stimulation of lipid peroxidation or 4-hydroxynonenal treatment increases procollagen alpha 1 (I) gene expression in human liver fat-storing cells

artículo científico publicado en 1993

Structure-activity relationships of calmodulin antagonism by triphenylethylene antiestrogens

artículo científico publicado en 1986

The biphasic nature of hypoxia-induced directional migration of activated human hepatic stellate cells

artículo científico publicado en 2011

The mitogen-activated protein kinase ERK5 regulates the development and growth of hepatocellular carcinoma.

artículo científico publicado en 2014

The role of redox mechanisms in hepatic chronic wound healing and fibrogenesis

artículo científico publicado en 2012

The up-regulation of BACE1 mediated by hypoxia and ischemic injury: role of oxidative stress and HIF1alpha

artículo científico publicado en 2009

Thrombopoietin stimulates migration and activates multiple signaling pathways in hepatoblastoma cells.

artículo científico publicado en 2005

Upregulation of proinflammatory and proangiogenic cytokines by leptin in human hepatic stellate cells.

artículo científico publicado en 2005

Vitamin E dietary supplementation inhibits transforming growth factor beta 1 gene expression in the rat liver

artículo científico publicado en 1992

Vitamin E dietary supplementation protects against carbon tetrachloride-induced chronic liver damage and cirrhosis

artículo científico publicado en 1992

[Effects of alpha lipoic acid and pirfenidone on liver cells antioxidant modulation against oxidative damage]

scientific article published on 01 December 2014

n-3 polyunsaturated fatty acids worsen inflammation and fibrosis in experimental nonalcoholic steatohepatitis

artículo científico publicado en 2014

Lista de obras de Maurizio Parola

4-Hydroxynonenal as a selective pro-fibrogenic stimulus for activated human hepatic stellate cells

Adipokines and redox signaling: impact on fatty liver disease

Age-dependent changes in extracellular matrix turnover: An under evaluated issue in the approach to chronic liver diseases

Alteration of Na+ homeostasis as a critical step in the development of irreversible hepatocyte injury after adenosine triphosphate depletion

Angiogenesis and Fibrogenesis in Chronic Liver Diseases

Beta-catenin triggers nuclear factor kappaB-dependent up-regulation of hepatocyte inducible nitric oxide synthase

Beta-site APP cleaving enzyme up-regulation induced by 4-hydroxynonenal is mediated by stress-activated protein kinases pathways.

Biochemical studies on bile duct epithelial cells isolated from rat liver

Calcium receptors located in fibrotic septa: a new target to reduce portal pressure in liver cirrhosis

Calcium-dependent diuretic system in preascitic liver cirrhosis

Celecoxib inactivates epithelial-mesenchymal transition stimulated by hypoxia and/or epidermal growth factor in colon cancer cells

Corrigendum to “Silibinin improves hepatic and myocardial injury in mice with nonalcoholic steatohepatitis” [Dig. Liver Dis. 44 (2012) 334–342]

Curcumin limits the fibrogenic evolution of experimental steatohepatitis.

Dehydroepiandrosterone modulates nuclear factor-kappaB activation in hippocampus of diabetic rats

Detection of cytochrome P4503A (CYP3A) in human hepatic stellate cells.

Dissection of the biphasic nature of hypoxia-induced motogenic action in bone marrow-derived human mesenchymal stem cells.

Dose dependent and divergent effects of superoxide anion on cell death, proliferation, and migration of activated human hepatic stellate cells

Dose-dependency of clonidine's effects in ascitic cirrhotic rats: comparison with α1-adrenergic agonist midodrine.

ERK Pathway in Activated, Myofibroblast-Like, Hepatic Stellate Cells: A Critical Signaling Crossroad Sustaining Liver Fibrosis

Effects of carbon tetrachloride on calcium homeostasis. A critical reconsideration

Endocellular polyamine availability modulates epithelial-to-mesenchymal transition and unfolded protein response in MDCK cells.

Endogenous annexin A1 is a novel protective determinant in nonalcoholic steatohepatitis in mice.

Expression of Cox-2 in human breast cancer cells as a critical determinant of epithelial-to-mesenchymal transition and invasiveness

Expression of platelet-derived growth factor in newly formed cholangiocytes during experimental biliary fibrosis in rats

Fat-laden macrophages modulate lobular inflammation in nonalcoholic steatohepatitis (NASH).

H2O2 and 4-hydroxynonenal mediate amyloid beta-induced neuronal apoptosis by activating JNKs and p38MAPK.

Hepatic myofibroblasts and fibrogenic progression of chronic liver diseases

Hepatic progenitor cells express SerpinB3

Hepatic wound repair

Hepatocellular metabolism of 4-hydroxy-2,3-nonenal is impaired in conditions of chronic cholestasis

Human hepatic stellate cells express class I alcohol dehydrogenase and aldehyde dehydrogenase but not cytochrome P4502E1.

Human mesenchymal stem cells as a two-edged sword in hepatic regenerative medicine: engraftment and hepatocyte differentiation versus profibrogenic potential

Human-induced pluripotent stem cells as a source of hepatocyte-like cells: new kids on the block

Hypoxia, angiogenesis and liver fibrogenesis in the progression of chronic liver diseases

Induction of Procollagen Type I Gene Expression and Synthesis in Human Hepatic Stellate Cells by 4-Hydroxy-2,3-Nonenal and Other 4-Hydroxy-2,3-Alkenals Is Related to Their Molecular Structure

Inhibition of the high affinity Ca2(+)-ATPase activity in rat liver plasma membranes following carbon tetrachloride intoxication

Interaction between 4-hydroxy-2,3-alkenals and the platelet-derived growth factor-beta receptor. Reduced tyrosine phosphorylation and downstream signaling in hepatic stellate cells

Intracellular free iron and acidic pathways mediate TNF-induced death of rat hepatoma cells.

Intracellular reactive oxygen species are required for directional migration of resident and bone marrow-derived hepatic pro-fibrogenic cells.

Isolation and characterization of biliary epithelial cells from normal rat liver

Lipid-induced toxicity stimulates hepatocytes to release angiogenic microparticles that require Vanin-1 for uptake by endothelial cells

Liver AP-1 activation due to carbon tetrachloride is potentiated by 1,2-dibromoethane but is inhibited by alpha-tocopherol or gadolinium chloride

Liver fibrogenic cells ⬇️

Liver/kidney microsomal antibody type 1 targets CYP2D6 on hepatocyte plasma membrane.

Mammalian target of rapamycin mediates the angiogenic effects of leptin in human hepatic stellate cells

Menadione and cumene hydroperoxide induced cytotoxicity in biliary epithelial cells isolated from rat liver

Mitochondrial damage and its role in causing hepatocyte injury during stimulation of lipid peroxidation by iron nitriloacetate

Modulation of hepatic fibrogenesis by antioxidants.

Multiple signaling events in amyloid beta-induced, oxidative stress-dependent neuronal apoptosis

Myofibroblast - like cells and liver fibrogenesis: Emerging concepts in a rapidly moving scenario.

Neutral endopeptidase (EC 3.4.24.11) in cirrhotic liver: a new target to treat portal hypertension?

Of FACT complex and oxidative stress response: a KEAP1/NRF2-dependent novel mechanism sustaining hepatocellular carcinoma progression

On the role of lipid peroxidation in the pathogenesis of liver damage induced by long-standing cholestasis

Overexpression of Bcl-2 by activated human hepatic stellate cells: resistance to apoptosis as a mechanism of progressive hepatic fibrogenesis in humans.

Oxidative damage and fibrogenesis

Oxidative stress-related molecules and liver fibrosis

Pathogenesis of solute-free water retention in experimental ascitic cirrhosis: is vasopressin the only culprit?

Phosphatidylinositol 3-kinase is required for platelet-derived growth factor's actions on hepatic stellate cells

Prevention of severe toxic liver injury and oxidative stress in MCP-1-deficient mice

Redox mechanisms in hepatic chronic wound healing and fibrogenesis

Redox mechanisms switch on hypoxia-dependent epithelial-mesenchymal transition in cancer cells

Resistin as an intrahepatic cytokine: overexpression during chronic injury and induction of proinflammatory actions in hepatic stellate cells

SERPINB3 induces epithelial-mesenchymal transition

SerpinB3 Differently Up-Regulates Hypoxia Inducible Factors -1α and -2α in Hepatocellular Carcinoma: Mechanisms Revealing Novel Potential Therapeutic Targets

SerpinB3 and Yap Interplay Increases Myc Oncogenic Activity.

Silibinin improves hepatic and myocardial injury in mice with nonalcoholic steatohepatitis.

Stem and progenitor cells in liver regeneration and repair.

Stem cells in liver failure

Stimulation of lipid peroxidation increases the intracellular calcium content of isolated hepatocytes

Stimulation of lipid peroxidation or 4-hydroxynonenal treatment increases procollagen alpha 1 (I) gene expression in human liver fat-storing cells

Structure-activity relationships of calmodulin antagonism by triphenylethylene antiestrogens

The biphasic nature of hypoxia-induced directional migration of activated human hepatic stellate cells

The mitogen-activated protein kinase ERK5 regulates the development and growth of hepatocellular carcinoma.

The role of redox mechanisms in hepatic chronic wound healing and fibrogenesis

The up-regulation of BACE1 mediated by hypoxia and ischemic injury: role of oxidative stress and HIF1alpha

Thrombopoietin stimulates migration and activates multiple signaling pathways in hepatoblastoma cells.

Upregulation of proinflammatory and proangiogenic cytokines by leptin in human hepatic stellate cells.

Vitamin E dietary supplementation inhibits transforming growth factor beta 1 gene expression in the rat liver

Vitamin E dietary supplementation protects against carbon tetrachloride-induced chronic liver damage and cirrhosis