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Lista de obras de Claire J Cairney

A 'synthetic-sickness' screen for senescence re-engagement targets in mutant cancer backgrounds

artículo científico publicado en 2017

A gene expression signature classifying telomerase and ALT immortalization reveals an hTERT regulatory network and suggests a mesenchymal stem cell origin for ALT.

artículo científico publicado en 2009

A small molecule modulator of prion protein increases human mesenchymal stem cell lifespan, ex vivo expansion, and engraftment to bone marrow in NOD/SCID mice

artículo científico publicado en 2012

A systems biology approach to Down syndrome: identification of Notch/Wnt dysregulation in a model of stem cells aging.

artículo científico publicado en 2009

Annexin A8 identifies a subpopulation of transiently quiescent c-kit positive luminal progenitor cells of the ductal mammary epithelium.

artículo científico publicado en 2015

Cancer cell senescence: a new frontier in drug development.

artículo científico

Cell-based screen for altered nuclear phenotypes reveals senescence progression in polyploid cells after Aurora kinase B inhibition

artículo científico publicado en 2015

Dynamic telomerase gene suppression via network effects of GSK3 inhibition

artículo científico publicado en 2009

Ectopically hTERT expressing adult human mesenchymal stem cells are less radiosensitive than their telomerase negative counterpart

scientific article published on 08 January 2007

Identification of a Selective G1-Phase Benzimidazolone Inhibitor by a Senescence-Targeted Virtual Screen Using Artificial Neural Networks

artículo científico publicado en 2015

Isolation, culture, and transfection of melanocytes

artículo científico

Mathematical model of a telomerase transcriptional regulatory network developed by cell-based screening: analysis of inhibitor effects and telomerase expression mechanisms

artículo científico publicado en 2014

Pathway analysis of senescence-associated miRNA targets reveals common processes to different senescence induction mechanisms

scientific article published on 12 February 2009

Scoring of senescence signalling in multiple human tumour gene expression datasets, identification of a correlation between senescence score and drug toxicity in the NCI60 panel and a pro-inflammatory signature correlating with survival [...]

artículo científico publicado en 2010

TCEAL7 inhibition of c-Myc activity in alternative lengthening of telomeres regulates hTERT expression

artículo científico publicado en 2010

Targeting the telomere and shelterin complex for cancer therapy: current views and future perspectives.

scientific article published on February 2011

The PTEN regulator DJ-1 is associated with hTERT expression in clear cell renal cell carcinoma

artículo científico publicado en 2009

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