Lista de obras - Kazuya Shinmura - Dominio Público Uruguay

8-hydroxyguanine (7,8-dihydro-8-oxoguanine) DNA glycosylase and AP lyase activities of hOGG1 protein and their substrate specificity

scientific article published on 01 October 1997

A novel APC mosaicism in a patient with familial adenomatous polyposis

artículo científico publicado en 2015

A novel STK11 germline mutation in two siblings with Peutz-Jeghers syndrome complicated by primary gastric cancer.

artículo científico publicado en 2005

A novel somatic FGFR3 mutation in primary lung cancer

artículo científico publicado en 2014

A novel splice-site variant of the base excision repair gene MYH is associated with production of an aberrant mRNA transcript encoding a truncated MYH protein not localized in the nucleus.

artículo científico publicado en 2004

A novel tumor-derived SGOL1 variant causes abnormal mitosis and unstable chromatid cohesion

artículo científico publicado en 2011

A single nucleotide polymorphism at the splice donor site of the human MYH base excision repair genes results in reduced translation efficiency of its transcripts

artículo científico publicado en 2002

Aberrant expression and mutation-inducing activity of AID in human lung cancer.

artículo científico publicado en 2011

Abnormal Expressions of DNA Glycosylase Genes NEIL1, NEIL2, and NEIL3 Are Associated with Somatic Mutation Loads in Human Cancer

artículo científico publicado en 2016

Accumulated phosphatidylcholine (16:0/16:1) in human colorectal cancer; possible involvement of LPCAT4.

artículo científico publicado en 2013

Adenine DNA glycosylase activity of 14 human MutY homolog (MUTYH) variant proteins found in patients with colorectal polyposis and cancer

scientific journal article

Adenine excisional repair function of MYH protein on the adenine:8-hydroxyguanine base pair in double-stranded DNA.

artículo científico publicado en 2000

Altered expression of the human base excision repair gene NTH1 in gastric cancer

artículo científico publicado en 2009

Anaplastic changes of diffuse leptomeningeal glioneuronal tumor with polar spongioblastoma pattern

scientific article published on 26 July 2018

Association between CDH1 haplotypes and gastric cancer risk in a Japanese population

artículo científico publicado en 2007

Association between dopamine beta hydroxylase rs5320 polymorphism and smoking behaviour in elderly Japanese

artículo científico publicado en 2012

Association between genetic polymorphisms of the base excision repair gene MUTYH and increased colorectal cancer risk in a Japanese population

artículo científico publicado en 2008

Association between neurexin 1 (NRXN1) polymorphisms and the smoking behavior of elderly Japanese

artículo científico publicado en 2010

Association between neuropeptide Y receptor 2 polymorphism and the smoking behavior of elderly Japanese

artículo científico publicado en 2010

BSND and ATP6V1G3: Novel Immunohistochemical Markers for Chromophobe Renal Cell Carcinoma

artículo científico publicado en 2015

BSND is a Novel Immunohistochemical Marker for Oncocytic Salivary Gland Tumors

artículo científico publicado en 2017

CD44-SLC1A2 fusion transcripts in primary colorectal cancer

artículo científico publicado en 2015

CD74-ROS1 fusion transcripts in resected non-small cell lung carcinoma

artículo científico publicado en 2013

CLCA2 as a novel immunohistochemical marker for differential diagnosis of squamous cell carcinoma from adenocarcinoma of the lung

artículo científico publicado en 2014

Causation of Borrmann type 4 gastric cancer: heritable factors or environmental factors?

scientific article published on 01 January 2003

Characterization of V-set and immunoglobulin domain containing 1 exerting a tumor suppressor function in gastric, lung, and esophageal cancer cells.

artículo científico publicado en 2017

Characterization of adenocarcinoma of the lung in a familial adenomatous polyposis patient.

artículo científico publicado en 2008

Characterization of centrosomal association of nucleophosmin/B23 linked to Crm1 activity

scientific journal article

Chromogenic in situ hybridization (CISH) to detect HER2 gene amplification in breast and gastric cancer: comparison with immunohistochemistry (IHC) and fluorescence in situ hybridization (FISH)

artículo científico publicado en 2012

Clinical analysis of false-negative fine needle aspiration cytology of head and neck cancers

scientific article published on 17 December 2018

Clinical significance of PD-L1 and PD-L2 copy number gains in non-small-cell lung cancer

scientific article published on April 2016

Clinicopathological and Survival Analysis of Japanese Patients with Resected Non-Small-Cell Lung Cancer Harboring NKX2-1, SETDB1, MET, HER2, SOX2, FGFR1, or PIK3CA Gene Amplification

artículo científico publicado en 2015

Cloning of a human homolog of the yeast OGG1 gene that is involved in the repair of oxidative DNA damage

artículo científico publicado en 1997

Defective repair capacity of variant proteins of the DNA glycosylase NTHL1 for 5-hydroxyuracil, an oxidation product of cytosine

scientific article published on 12 December 2018

Detection of kinase amplifications in gastric cancer archives using fluorescence in situ hybridization.

artículo científico publicado en 2012

Detection of lipid peroxidation-induced DNA adducts caused by 4-oxo-2(E)-nonenal and 4-oxo-2(E)-hexenal in human autopsy tissues

artículo científico publicado en 2010

Direct evidence for the role of centrosomally localized p53 in the regulation of centrosome duplication

artículo científico publicado en 2006

Distinct prognostic roles and heterogeneity of TTF1 copy number and TTF1 protein expression in non-small cell lung cancer.

artículo científico publicado en 2017

Downregulation of EphA7 by hypermethylation in colorectal cancer

artículo científico publicado en 2005

E-cadherin gene variants in gastric cancer families whose probands are diagnosed with diffuse gastric cancer

artículo científico publicado en 2002

EML4-ALK fusion transcripts in immunohistochemically ALK-positive non-small cell lung carcinomas.

artículo científico publicado en 2010

EML4-ALK fusion transcripts, but no NPM-, TPM3-, CLTC-, ATIC-, or TFG-ALK fusion transcripts, in non-small cell lung carcinomas

artículo científico publicado en 2008

EPH-EPHRIN in human gastrointestinal cancers

artículo científico publicado en 2010

EPHA2/EFNA1 expression in human gastric cancer.

artículo científico publicado en 2005

Effect of boron neutron capture therapy for recurrent anaplastic meningioma: an autopsy case report

artículo científico publicado en 2014

Effect of splice-site polymorphisms of the TMPRSS4, NPHP4 and ORCTL4 genes on their mRNA expression

artículo científico publicado en 2005

Enhancement of OGG1 protein AP lyase activity by increase of APEX protein

artículo científico publicado en 2001

Familial gastric cancer: clinicopathological characteristics, RER phenotype and germline p53 and E-cadherin mutations

artículo científico publicado en 1999

Fluorescence-labeled methylation-sensitive amplified fragment length polymorphism (FL-MS-AFLP) analysis for quantitative determination of DNA methylation and demethylation status

artículo científico publicado en 2008

Frequent PTPRK-RSPO3 fusions and RNF43 mutations in colorectal traditional serrated adenoma.

artículo científico publicado en 2016

Frequent co-occurrence of mutator phenotype in synchronous, independent multiple cancers of the stomach

scientific article published on 01 December 1995

Functional Evaluation of Nine Missense-Type Variants of the Human DNA Glycosylase Enzyme MUTYH in the Japanese Population

artículo científico publicado en 2015

Genes Located on 18q23 Are Epigenetic Markers and Have Prognostic Significance for Patients with Head and Neck Cancer

article

Genes encoding neuropeptide receptors are epigenetic markers in patients with head and neck cancer: a site-specific analysis.

artículo científico publicado en 2017

Germline alterations in the CDH1 gene in familial gastric cancer in the Japanese population

artículo científico publicado en 2011

Germline p53 mutation in a patient with multiple primary cancers

scientific article published on 01 July 2001

Heterogeneity analysis of PD-L1 expression and copy number status in EBUS-TBNA biopsy specimens of non-small cell lung cancer: Comparative assessment of primary and metastatic sites

artículo científico publicado en 2019

Human DNA glycosylase enzyme TDG repairs thymine mispaired with exocyclic etheno-DNA adducts.

artículo científico publicado en 2014

Human Sgo1 downregulation leads to chromosomal instability in colorectal cancer

artículo científico publicado en 2008

Identification and association study with lung cancer for novel insertion polymorphisms of human endogenous retrovirus

artículo científico publicado en 2013

Identification and characterization of a novel germ line p53 mutation in familial gastric cancer in the Japanese population

artículo científico publicado en 2007

Identification and characterization of a novel germline p53 mutation in a patient with glioblastoma and colon cancer

artículo científico publicado en 2009

Identification of 5 novel germline APC mutations and characterization of clinical phenotypes in Japanese patients with classical and attenuated familial adenomatous polyposis

artículo científico publicado en 2010

Ile-Leu substitution (I415L) in germline E-cadherin gene (CDH1) in Japanese familial gastric cancer

artículo científico publicado en 2003

Impaired 8-hydroxyguanine repair activity of MUTYH variant p.Arg109Trp found in a Japanese patient with early-onset colorectal cancer

scientific article published on 23 March 2014

Impaired suppressive activities of human MUTYH variant proteins against oxidative mutagenesis

artículo científico publicado en 2012

Inactivating mutations of the human base excision repair gene NEIL1 in gastric cancer

artículo científico publicado en 2004

Induction of centrosome amplification and chromosome instability in p53-deficient lung cancer cells exposed to benzo[a]pyrene diol epoxide (B[a]PDE).

artículo científico publicado en 2008

Inverse relationship between the length of the EGFR CA repeat polymorphism in lung carcinoma and protein expression of EGFR in the carcinoma

scientific article published on 01 November 2008

Lipid peroxidation-induced DNA adducts in human gastric mucosa

artículo científico publicado en 2012

Mediastinal mature teratoma with complete gastrointestinal and bronchial walls

artículo científico publicado en 2015

Mesothelial/monocytic incidental cardiac excrescence with bone marrow.

artículo científico publicado en 2018

Microsatellite instability and K-ras mutations in gastric adenomas, with reference to associated gastric cancers

artículo científico publicado en 1999

Mutation Spectrum Induced by 8-Bromoguanine, a Base Damaged by Reactive Brominating Species, in Human Cells

artículo científico publicado en 2017

NEIL1 p.Gln282Stop variant is predominantly localized in the cytoplasm and exhibits reduced activity in suppressing mutations

artículo científico publicado en 2015

Neoadjuvant imatinib treatment and laparoscopic anus-preserving surgery for a large gastrointestinal stromal tumor of the rectum

artículo científico publicado en 2016

Novel roles for LIX1L in promoting cancer cell proliferation through ROS1-mediated LIX1L phosphorylation

artículo científico publicado en 2015

OGG1 protein suppresses G:C-->T:A mutation in a shuttle vector containing 8-hydroxyguanine in human cells

artículo científico publicado en 2001

OGG1, MYH and MTH1 gene variants identified in gastric cancer patients exhibiting both 8-hydroxy-2'-deoxyguanosine accumulation and low inflammatory cell infiltration in their gastric mucosa

artículo científico publicado en 2008

POLQ Overexpression Is Associated with an Increased Somatic Mutation Load and PLK4 Overexpression in Lung Adenocarcinoma

artículo científico publicado en 2019

Prognostic impact of CD73 and A2A adenosine receptor expression in non-small-cell lung cancer

artículo científico publicado en 2017

Promoter methylation of galanin receptors as epigenetic biomarkers for head and neck squamous cell carcinomas

scientific article published on 21 January 2019

RER phenotype and its associated mutations in familial gastric cancer

scientific article published on 01 February 1998

RSPO fusion transcripts in colorectal cancer in Japanese population

artículo científico publicado en 2014

Reduced expression of MUTYH with suppressive activity against mutations caused by 8-hydroxyguanine is a novel predictor of a poor prognosis in human gastric cancer

artículo científico publicado en 2011

Robust quantitative assessments of cytosine modifications and changes in the expressions of related enzymes in gastric cancer

artículo científico publicado en 2014

SASS6 overexpression is associated with mitotic chromosomal abnormalities and a poor prognosis in patients with colorectal cancer

artículo científico publicado en 2015

Site-specific methylation patterns of the GAL and GALR1/2 genes in head and neck cancer: Potential utility as biomarkers for prognosis

artículo científico publicado en 2016

Somatic mutations and single nucleotide polymorphisms of base excision repair genes involved in the repair of 8-hydroxyguanine in damaged DNA.

artículo científico publicado en 2001

Suppression of hydroxyurea-induced centrosome amplification by NORE1A and down-regulation of NORE1A mRNA expression in non-small cell lung carcinoma

artículo científico publicado en 2011

Suppressive activities of OGG1 and MYH proteins against G:C to T:A mutations caused by 8-hydroxyguanine but not by benzo[a]pyrene diol epoxide in human cells in vivo

artículo científico publicado en 2003

TNK2 gene amplification is a novel predictor of a poor prognosis in patients with gastric cancer

artículo científico publicado en 2013

The CRKL gene encoding an adaptor protein is amplified, overexpressed, and a possible therapeutic target in gastric cancer ⬇️

artículo científico publicado el 3 de julio de 2012

Thr199 phosphorylation targets nucleophosmin to nuclear speckles and represses pre-mRNA processing

scientific journal article

Tiam1 mediates neurite outgrowth induced by ephrin-B1 and EphA2

scientific journal article

WDR62 overexpression is associated with a poor prognosis in patients with lung adenocarcinoma

artículo científico publicado en 2017

Lista de obras de Kazuya Shinmura

8-hydroxyguanine (7,8-dihydro-8-oxoguanine) DNA glycosylase and AP lyase activities of hOGG1 protein and their substrate specificity

A novel APC mosaicism in a patient with familial adenomatous polyposis

A novel STK11 germline mutation in two siblings with Peutz-Jeghers syndrome complicated by primary gastric cancer.

A novel somatic FGFR3 mutation in primary lung cancer

A novel splice-site variant of the base excision repair gene MYH is associated with production of an aberrant mRNA transcript encoding a truncated MYH protein not localized in the nucleus.

A novel tumor-derived SGOL1 variant causes abnormal mitosis and unstable chromatid cohesion

A single nucleotide polymorphism at the splice donor site of the human MYH base excision repair genes results in reduced translation efficiency of its transcripts

Aberrant expression and mutation-inducing activity of AID in human lung cancer.

Abnormal Expressions of DNA Glycosylase Genes NEIL1, NEIL2, and NEIL3 Are Associated with Somatic Mutation Loads in Human Cancer

Accumulated phosphatidylcholine (16:0/16:1) in human colorectal cancer; possible involvement of LPCAT4.

Adenine DNA glycosylase activity of 14 human MutY homolog (MUTYH) variant proteins found in patients with colorectal polyposis and cancer

Adenine excisional repair function of MYH protein on the adenine:8-hydroxyguanine base pair in double-stranded DNA.

Altered expression of the human base excision repair gene NTH1 in gastric cancer

Anaplastic changes of diffuse leptomeningeal glioneuronal tumor with polar spongioblastoma pattern

Association between CDH1 haplotypes and gastric cancer risk in a Japanese population

Association between dopamine beta hydroxylase rs5320 polymorphism and smoking behaviour in elderly Japanese

Association between genetic polymorphisms of the base excision repair gene MUTYH and increased colorectal cancer risk in a Japanese population

Association between neurexin 1 (NRXN1) polymorphisms and the smoking behavior of elderly Japanese

Association between neuropeptide Y receptor 2 polymorphism and the smoking behavior of elderly Japanese

BSND and ATP6V1G3: Novel Immunohistochemical Markers for Chromophobe Renal Cell Carcinoma

BSND is a Novel Immunohistochemical Marker for Oncocytic Salivary Gland Tumors

CD44-SLC1A2 fusion transcripts in primary colorectal cancer

CD74-ROS1 fusion transcripts in resected non-small cell lung carcinoma

CLCA2 as a novel immunohistochemical marker for differential diagnosis of squamous cell carcinoma from adenocarcinoma of the lung

Causation of Borrmann type 4 gastric cancer: heritable factors or environmental factors?

Characterization of V-set and immunoglobulin domain containing 1 exerting a tumor suppressor function in gastric, lung, and esophageal cancer cells.

Characterization of adenocarcinoma of the lung in a familial adenomatous polyposis patient.

Characterization of centrosomal association of nucleophosmin/B23 linked to Crm1 activity

Chromogenic in situ hybridization (CISH) to detect HER2 gene amplification in breast and gastric cancer: comparison with immunohistochemistry (IHC) and fluorescence in situ hybridization (FISH)

Clinical analysis of false-negative fine needle aspiration cytology of head and neck cancers

Clinical significance of PD-L1 and PD-L2 copy number gains in non-small-cell lung cancer

Clinicopathological and Survival Analysis of Japanese Patients with Resected Non-Small-Cell Lung Cancer Harboring NKX2-1, SETDB1, MET, HER2, SOX2, FGFR1, or PIK3CA Gene Amplification

Cloning of a human homolog of the yeast OGG1 gene that is involved in the repair of oxidative DNA damage

Defective repair capacity of variant proteins of the DNA glycosylase NTHL1 for 5-hydroxyuracil, an oxidation product of cytosine

Detection of kinase amplifications in gastric cancer archives using fluorescence in situ hybridization.

Detection of lipid peroxidation-induced DNA adducts caused by 4-oxo-2(E)-nonenal and 4-oxo-2(E)-hexenal in human autopsy tissues

Direct evidence for the role of centrosomally localized p53 in the regulation of centrosome duplication

Distinct prognostic roles and heterogeneity of TTF1 copy number and TTF1 protein expression in non-small cell lung cancer.

Downregulation of EphA7 by hypermethylation in colorectal cancer

E-cadherin gene variants in gastric cancer families whose probands are diagnosed with diffuse gastric cancer

EML4-ALK fusion transcripts in immunohistochemically ALK-positive non-small cell lung carcinomas.

EML4-ALK fusion transcripts, but no NPM-, TPM3-, CLTC-, ATIC-, or TFG-ALK fusion transcripts, in non-small cell lung carcinomas

EPH-EPHRIN in human gastrointestinal cancers

EPHA2/EFNA1 expression in human gastric cancer.

Effect of boron neutron capture therapy for recurrent anaplastic meningioma: an autopsy case report

Effect of splice-site polymorphisms of the TMPRSS4, NPHP4 and ORCTL4 genes on their mRNA expression

Enhancement of OGG1 protein AP lyase activity by increase of APEX protein

Familial gastric cancer: clinicopathological characteristics, RER phenotype and germline p53 and E-cadherin mutations

Fluorescence-labeled methylation-sensitive amplified fragment length polymorphism (FL-MS-AFLP) analysis for quantitative determination of DNA methylation and demethylation status

Frequent PTPRK-RSPO3 fusions and RNF43 mutations in colorectal traditional serrated adenoma.

Frequent co-occurrence of mutator phenotype in synchronous, independent multiple cancers of the stomach

Functional Evaluation of Nine Missense-Type Variants of the Human DNA Glycosylase Enzyme MUTYH in the Japanese Population

Genes Located on 18q23 Are Epigenetic Markers and Have Prognostic Significance for Patients with Head and Neck Cancer

Genes encoding neuropeptide receptors are epigenetic markers in patients with head and neck cancer: a site-specific analysis.

Germline alterations in the CDH1 gene in familial gastric cancer in the Japanese population

Germline p53 mutation in a patient with multiple primary cancers

Heterogeneity analysis of PD-L1 expression and copy number status in EBUS-TBNA biopsy specimens of non-small cell lung cancer: Comparative assessment of primary and metastatic sites

Human DNA glycosylase enzyme TDG repairs thymine mispaired with exocyclic etheno-DNA adducts.

Human Sgo1 downregulation leads to chromosomal instability in colorectal cancer

Identification and association study with lung cancer for novel insertion polymorphisms of human endogenous retrovirus

Identification and characterization of a novel germ line p53 mutation in familial gastric cancer in the Japanese population

Identification and characterization of a novel germline p53 mutation in a patient with glioblastoma and colon cancer

Identification of 5 novel germline APC mutations and characterization of clinical phenotypes in Japanese patients with classical and attenuated familial adenomatous polyposis

Ile-Leu substitution (I415L) in germline E-cadherin gene (CDH1) in Japanese familial gastric cancer

Impaired 8-hydroxyguanine repair activity of MUTYH variant p.Arg109Trp found in a Japanese patient with early-onset colorectal cancer

Impaired suppressive activities of human MUTYH variant proteins against oxidative mutagenesis

Inactivating mutations of the human base excision repair gene NEIL1 in gastric cancer

Induction of centrosome amplification and chromosome instability in p53-deficient lung cancer cells exposed to benzo[a]pyrene diol epoxide (B[a]PDE).

Inverse relationship between the length of the EGFR CA repeat polymorphism in lung carcinoma and protein expression of EGFR in the carcinoma

Lipid peroxidation-induced DNA adducts in human gastric mucosa

Mediastinal mature teratoma with complete gastrointestinal and bronchial walls

Mesothelial/monocytic incidental cardiac excrescence with bone marrow.

Microsatellite instability and K-ras mutations in gastric adenomas, with reference to associated gastric cancers

Mutation Spectrum Induced by 8-Bromoguanine, a Base Damaged by Reactive Brominating Species, in Human Cells

NEIL1 p.Gln282Stop variant is predominantly localized in the cytoplasm and exhibits reduced activity in suppressing mutations

Neoadjuvant imatinib treatment and laparoscopic anus-preserving surgery for a large gastrointestinal stromal tumor of the rectum

Novel roles for LIX1L in promoting cancer cell proliferation through ROS1-mediated LIX1L phosphorylation

OGG1 protein suppresses G:C-->T:A mutation in a shuttle vector containing 8-hydroxyguanine in human cells

OGG1, MYH and MTH1 gene variants identified in gastric cancer patients exhibiting both 8-hydroxy-2'-deoxyguanosine accumulation and low inflammatory cell infiltration in their gastric mucosa