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Lista de obras de Paula Soares

"The other side of the coin": understanding noninvasive follicular tumor with papillary-like nuclear features in unifocal and multifocal settings

scientific article published on 08 December 2018

A 30-Year Long-Term Experience in Appendix Neuroendocrine Neoplasms-Granting a Positive Outcome

artículo científico publicado en 2020

A Polymorphism in the Promoter Region of the Selenoprotein S Gene (SEPS1) Contributes to Hashimoto's Thyroiditis Susceptibility

article

A clear cell renal cell carcinoma inhibiting the response to intravitreal antivascular endothelial growth factor therapy in wet age-related macular disease

artículo científico publicado en 2012

A follicular variant of papillary thyroid carcinoma in struma ovarii. Case report with unique molecular alterations.

artículo científico publicado en 2009

A founder SDHB mutation in Portuguese paraganglioma patients

article

A novel germline SDHB mutation in a gastrointestinal stromal tumor patient without bona fide features of the Carney–Stratakis dyad

artículo científico publicado en 2012

A stem cell role for thyroid solid cell nests.

artículo científico publicado en 2005

A subset of colorectal carcinomas express c-KIT protein independently of BRAF and/or KRAS activation

artículo científico publicado en 2007

Abnormalities of the E-cadherin/catenin adhesion complex in classical papillary thyroid carcinoma and in its diffuse sclerosing variant

artículo científico publicado en 2001

Absence of theBRAFand theGRIM-19Mutations in Oncocytic (Hürthle Cell) Solid Cell Nests of the Thyroid

scientific article published on 01 April 2012

Acquisition of BRAF gene mutations is not a requirement for nodal metastasis of papillary thyroid carcinoma

artículo científico publicado en 2008

Adenomas and follicular carcinomas of the thyroid display two major patterns of chromosomal changes

scientific article published on 01 July 2005

Age-Associated Mortality Risk in Papillary Thyroid Cancer: Does BRAF Make a Real Difference?

artículo científico publicado en 2018

Alopecia in women submitted to childhood X-ray epilation for tinea capitis treatment

artículo científico publicado en 2010

An assessment of the clonality of the components of canine mixed mammary tumours by mitochondrial DNA analysis.

artículo científico publicado en 2008

Analysis of GNAQ mutations, proliferation and MAPK pathway activation in uveal melanomas

artículo científico publicado en 2010

BRAF mutations and RET/PTC rearrangements are alternative events in the etiopathogenesis of PTC

artículo científico publicado en 2003

BRAF mutations are associated with some histological types of papillary thyroid carcinoma

artículo científico publicado en 2004

BRAF provides proliferation and survival signals in MSI colorectal carcinoma cells displaying BRAF(V600E) but not KRAS mutations

artículo científico publicado en 2008

BRAFV600Emutation in papillary thyroid carcinoma: a potential target for therapy?

artículo científico publicado en 2009

Benign and malignant thyroid lesions show instability at microsatellite loci

artículo científico publicado en 1997

Biomarkers for Bladder Cancer Diagnosis and Surveillance: A Comprehensive Review

scientific article published on 13 January 2020

C-Cell-Derived Calcitonin-Free Neuroendocrine Carcinoma of the Thyroid

artículo científico publicado en 2014

CDX2 Expression in Some Variants of Papillary Thyroid Carcinoma

artículo científico publicado en 2012

CRABP1, C1QL1 and LCN2 are biomarkers of differentiated thyroid carcinoma, and predict extrathyroidal extension

artículo científico publicado en 2018

Calcitonin receptor expression in medullary thyroid carcinoma

artículo científico publicado en 2017

Chromosomal, epigenetic and microRNA-mediated inactivation of LRP1B, a modulator of the extracellular environment of thyroid cancer cells

artículo científico publicado en 2010

Clinical Validation of a Urine Test (Uromonitor-V2®) for the Surveillance of Non-Muscle-Invasive Bladder Cancer Patients

scientific article published on 24 September 2020

Clinicopathological Features as Prognostic Predictors of Poor Outcome in Papillary Thyroid Carcinoma

artículo científico publicado en 2020

Clonal cytogenetic abnormalities and telomeric associations in a fibroxanthoma of the stomach

scientific article published on 01 November 1992

Coexistence of TERT promoter and BRAF mutations in papillary thyroid carcinoma: added value in patient prognosis?

artículo científico publicado en 2015

Comments on: Mutations in Mitochondrial Control Region DNA in Gastric Tumours of Japanese Patients, Tamura, et al. Eur J Cancer 1999, 35, 316–319

artículo científico publicado en 1999

Comprehensive Assessment of TERT mRNA Expression across a Large Cohort of Benign and Malignant Thyroid Tumours

artículo científico publicado en 2020

Core I gene is overexpressed in Hürthle and non-Hürthle cell microfollicular adenomas and follicular carcinomas of the thyroid

artículo científico publicado en 2004

Corrigendum to "How to Treat a Signal? Current Basis for RET-Genotype-Oriented Choice of Kinase Inhibitors for the Treatment of Medullary Thyroid Cancer".

artículo científico publicado en 2016

Cribriform-Morular Variant of Papillary Thyroid Carcinoma

scientific article published on 01 January 2009

Cribriform-Morular Variant of Papillary Thyroid Carcinoma Displaying Poorly Differentiated Features

artículo científico publicado en 2013

Cribriform-morular variant of thyroid carcinoma: a neoplasm with distinctive phenotype associated with the activation of the WNT/β-catenin pathway

artículo científico publicado en 2018

Cyclic AMP inhibits the proliferation of thyroid carcinoma cell lines through regulation of CDK4 phosphorylation

artículo científico publicado en 2008

Cystic tumor of the atrioventricular node of the heart appears to be the heart equivalent of the solid cell nests (ultimobranchial rests) of the thyroid

scientific article published on 01 March 2005

Cytogenetic findings in eleven gastric carcinomas.

artículo científico publicado en 1993

Differential Expression of HMGA1 and HMGA2 in pituitary neuroendocrine tumors

artículo científico publicado en 2019

Differentiated thyroid cancer in patients with resistance to thyroid hormone syndrome. A novel case and a review of the literature.

artículo científico publicado en 2014

Diffuse (or multinodular) follicular variant of papillary thyroid carcinoma: a clinicopathologic and immunohistochemical analysis of ten cases of an aggressive form of differentiated thyroid carcinoma.

artículo científico publicado en 2001

Dynamin-Related Protein 1 at the Crossroads of Cancer.

artículo científico publicado en 2018

E-cadherin gene (CDH1) promoter methylation as the second hit in sporadic diffuse gastric carcinoma

article

E-cadherin gene alterations are rare events in thyroid tumors

article

E-cadherin loss rather than beta-catenin alterations is a common feature of poorly differentiated thyroid carcinomas.

artículo científico publicado en 2003

EBV interferes with the sensitivity of Burkitt lymphoma Akata cells to etoposide

artículo científico publicado en 2011

ENDOCRINE TUMOURS: Genetic predictors of thyroid cancer outcome

artículo científico publicado en 2016

Erratum to "Gastroenteropancreatic Neuroendocrine Neoplasia Characterization in Portugal: Results from the NETs Study Group of the Portuguese Society of Endocrinology, Diabetes and Metabolism"

scientific article published on 18 June 2020

Erratum: Chromosomal, epigenetic and microRNA-mediated inactivation of LRP1B, a modulator of the extracellular environment of thyroid cancer cells

scientific article published on 08 August 2016

Etiopathogenesis of oncocytomas

artículo científico publicado en 2017

Evaluation of the mTOR pathway in ocular (uvea and conjunctiva) melanoma

artículo científico publicado en 2010

Extended structural variation of a pentanucleotide repeat in the GSTP1 gene: characterisation in a normal population and in thyroid and gastric tumours

article

Fetal adenomas and minimally invasive follicular carcinomas of the thyroid frequently display a triploid or near triploid DNA pattern

article

Follicular thyroid carcinoma with an unusual glomeruloid pattern of growth

artículo científico publicado en 2008

Follicular thyroid lesions: is there a discriminatory potential in the computerized nuclear analysis?

artículo científico publicado en 2018

Four novel MSH2 / MLH1 gene mutations in portuguese HNPCC families

artículo científico publicado en 2000

Frequency of TERT promoter mutations in human cancers

artículo científico publicado en 2013

Frontiers in endocrine disruption: Impacts of organotin on the hypothalamus-pituitary-thyroid axis

artículo científico publicado en 2017

GLUT1, MCT1/4 and CD147 overexpression supports the metabolic reprogramming in papillary renal cell carcinoma

artículo científico publicado en 2016

GNAQ and BRAF mutations show differential activation of the mTOR pathway in human transformed cells.

scientific article published on 23 July 2013

GRIM-19 function in cancer development

artículo científico publicado en 2011

GRIM-19 in Health and Disease.

artículo científico publicado en 2008

Gastroenteropancreatic Neuroendocrine Neoplasia Characterization in Portugal: Results from the NETs Study Group of the Portuguese Society of Endocrinology, Diabetes and Metabolism

artículo científico publicado en 2019

Genetic alterations in poorly differentiated and undifferentiated thyroid carcinomas

artículo científico publicado en 2011

Genetic alterations in thyroid tumors from patients irradiated in childhood for tinea capitis treatment

artículo científico publicado en 2013

Genomic and transcriptomic characterization of the mitochondrial-rich oncocytic phenotype on a thyroid carcinoma background.

artículo científico publicado en 2018

Germline succinate dehydrogenase subunit D mutation segregating with familial non-RET C cell hyperplasia.

artículo científico publicado en 2003

Germline variation of the melanocortin-1 receptor does not explain shared risk for melanoma and thyroid cancer.

artículo científico publicado en 2009

H-RAS 81 polymorphism is significantly associated with aneuploidy in follicular tumors of the thyroid

artículo científico publicado en 2006

Head and neck basal cell carcinoma prevalence in individuals submitted to childhood X-ray epilation for tinea capitis treatment

artículo científico publicado en 2012

Head and neck lesions in a cohort irradiated in childhood for tinea capitis treatment

scientific article published on 01 March 2011

Hobnail Variant of Papillary Thyroid Carcinoma: Clinicopathologic and Molecular Evidence of Progression to Undifferentiated Carcinoma in 2 Cases.

artículo científico publicado en 2016

Hotspot TERT promoter mutations are rare events in testicular germ cell tumors.

artículo científico publicado en 2015

How to Treat a Signal? Current Basis for RET-Genotype-Oriented Choice of Kinase Inhibitors for the Treatment of Medullary Thyroid Cancer

scientific article published on 23 June 2011

IL6-174 G>C Polymorphism (rs1800795) Association with Late Effects of Low Dose Radiation Exposure in the Portuguese Tinea Capitis Cohort

artículo científico publicado en 2016

Identification of a paired box gene 8–peroxisome proliferator-activated receptor gamma (PAX8–PPARγ) rearrangement mosaicism in a patient with an autonomous functioning follicular thyroid carcinoma bearing an activating mutation in the TSH recept

article

Immunohistochemical study of heat shock proteins 27, 60 and 70 in the normal human adrenal and in adrenal tumors with suppressed ACTH production.

artículo científico publicado en 2003

Impact of EGFR genetic variants on glioma risk and patient outcome.

artículo científico publicado en 2011

In vitro transforming potential, intracellular signaling properties, and sensitivity to a kinase inhibitor (sorafenib) of RET proto-oncogene variants Glu511Lys, Ser649Leu, and Arg886Trp

artículo científico publicado en 2011

Increased lymphangiogenesis in Riedel thyroiditis (Immunoglobulin G4-related thyroid disease)

artículo científico publicado en 2014

Inhibitory Effects of Antagonists of Growth Hormone-Releasing Hormone (GHRH) in Thyroid Cancer

artículo científico publicado en 2017

Insights into melanoma: targeting the mTOR pathway for therapeutics

artículo científico

Intragenic mutations in thyroid cancer.

scientific article published on June 2008

Intratumoural lymph vessel density is related to presence of lymph node metastases and separates encapsulated from infiltrative papillary thyroid carcinoma.

artículo científico publicado en 2011

Introduction

Involvement of p53 in cell death following cell cycle arrest and mitotic catastrophe induced by rotenone.

artículo científico publicado en 2011

Is BRAF mutation screening useful for preoperative risk stratification in papillary thyroid cancer?

artículo científico publicado en 2009

Is Low-Dose Radiation Exposure a Risk Factor for Atherosclerotic Disease?

scientific article published on 20 February 2018

Liposomal therapies in oncology: does one size fit all?

artículo científico publicado en 2018

Loss of Y chromosome in gastric carcinoma

artículo científico publicado en 1992

Loss of heterozygosity at 19p13.2 and 2q21 in tumours from familial clusters of non-medullary thyroid carcinoma

artículo científico publicado en 2007

Low frequency of TERT promoter mutations in gastrointestinal stromal tumors (GISTs).

artículo científico publicado en 2014

MEN1 intragenic deletions may represent the most prevalent somatic event in sporadic primary hyperparathyroidism.

artículo científico publicado en 2012

Melanocytic Tumour in a Black Sheep never exposed to Ultraviolet Radiation

artículo científico publicado en 2011

Melanoma treatment in review.

artículo científico publicado en 2018

Microsatellite instability, mitochondrial DNA large deletions, and mitochondrial DNA mutations in gastric carcinoma

artículo científico publicado en 2001

Mitochondrial D-Loop instability in thyroid tumours is not a marker of malignancy

scientific article published on 01 October 2005

Mitochondrial D310 D-Loop instability and histological subtypes in radiation-induced cutaneous basal cell carcinomas.

artículo científico publicado en 2013

Mitochondrial dynamics protein Drp1 is overexpressed in oncocytic thyroid tumors and regulates cancer cell migration

artículo científico publicado en 2015

Molecular Aspects of Thyroid Calcification

artículo científico publicado en 2020

Molecular Markers Involved in Tumorigenesis of Thyroid Carcinoma: Focus on Aggressive Histotypes

artículo científico publicado en 2017

Molecular alterations and expression of succinate dehydrogenase complex in wild-type KIT/PDGFRA/BRAF gastrointestinal stromal tumors.

artículo científico publicado en 2012

Molecular and genotypic characterization of human thyroid follicular cell carcinoma-derived cell lines

artículo científico publicado en 2007

Molecular profiling, including TERT promoter mutations, of acral lentiginous melanomas.

artículo científico publicado en 2016

Mucoepidermoid carcinoma of the thyroid: a tumour histotype characterised by P-cadherin neoexpression and marked abnormalities of E-cadherin/catenins complex.

artículo científico publicado en 2002

Multicentre validation study of nucleic acids extraction from FFPE tissues.

artículo científico publicado en 2010

Multinodular Goiter Progression Toward Malignancy in a Case of DICER1 Syndrome: Histologic and Molecular Alterations.

artículo científico publicado en 2018

Mutation analysis of B-RAF gene in human gliomas.

artículo científico publicado en 2004

NIS expression in thyroid tumors, relation with prognosis clinicopathological and molecular features

artículo científico publicado en 2018

Nrf2 is commonly activated in papillary thyroid carcinoma, and it controls antioxidant transcriptional responses and viability of cancer cells

artículo científico publicado en 2013

OPNa Overexpression Is Associated with Matrix Calcification in Thyroid Cancer Cell Lines

artículo científico publicado en 2018

OXPHOS dysfunction regulates integrin-β1 modifications and enhances cell motility and migration.

artículo científico publicado en 2014

Occurrence of the Cys611Tyr mutation and a novel Arg886Trp substitution in the RET proto-oncogene in multiple endocrine neoplasia type 2 families and sporadic medullary thyroid carcinoma cases originating from the central region of Portugal

artículo científico publicado en 2006

Optimization of methods to assess mitochondrial DNA in archival paraffin-embedded tissues from mammary canine tumors

article by Angélica C. Bertagnolli et al published August 2008 in Jornal brasileiro de patologia e medicina laboratorial

Orthovanadate-induced cell death in RET/PTC1-harboring cancer cells involves the activation of caspases and altered signaling through PI3K/Akt/mTOR.

artículo científico publicado en 2011

Osteopontin expression is correlated with differentiation and good prognosis in medullary thyroid carcinoma

artículo científico publicado en 2016

Osteopontin-a splice variant is overexpressed in papillary thyroid carcinoma and modulates invasive behavior

artículo científico publicado en 2016

Other Rare Tumours and Tumour-Like Lesions

Overexpression of pyruvate dehydrogenase kinase supports dichloroacetate as a candidate for cutaneous melanoma therapy.

artículo científico publicado en 2015

Papillary thyroid microcarcinoma: how to diagnose and manage this epidemic?

artículo científico publicado en 2014

Paraganglioma of seminal vesicle and chromophobe renal cell carcinoma: a case report and literature review.

artículo científico publicado en 2012

Polymorphisms in the TNFA and IL6 genes represent risk factors for autoimmune thyroid disease

artículo científico publicado en 2014

Poorly Differentiated and Undifferentiated Thyroid Carcinomas

artículo científico publicado en 2015

Predictive Biomarkers and Patient Outcome in Platinum-Resistant (PLD-Treated) Ovarian Cancer

artículo científico publicado en 2020

Primary squamous cell carcinoma of the thyroid diagnosed as anaplastic carcinoma: failure in fine-needle aspiration cytology?

artículo científico publicado en 2014

Prognostic Significance of RAS Mutations and P53 Expression in Cutaneous Squamous Cell Carcinomas

artículo científico publicado en 2020

Prognostic biomarkers in thyroid cancer

artículo científico publicado en 2014

Proliferation and survival molecules implicated in the inhibition of BRAF pathway in thyroid cancer cells harbouring different genetic mutations.

artículo científico publicado en 2009

Proliferative activity of human thyroid tumors evaluated by proliferating cell nuclear antigen/cyclin immunohistochemical studies

artículo científico publicado en 1994

RAF-1 promotes survival of thyroid cancer cells harboring RET/PTC1 rearrangement independently of ERK activation

artículo científico publicado en 2015

RE: TERT promoter mutation status as an independent prognostic factor in cutaneous melanoma.

artículo científico publicado en 2015

RET/PTC rearrangement is prevalent in follicular Hürthle cell carcinomas.

artículo científico publicado en 2012

Rare Familial Tumours

Rare Follicular Tumours

Rare Papillary Thyroid Carcinomas

Relative Y-STR mutation rates estimated from the variance inside SNP defined lineages

article

Reliable blood cancer cells' telomere length evaluation by qPCR

artículo científico publicado en 2020

Reply to: Low prevalence of BRAF mutations in radiation-induced thyroid tumors in contrast to sporadic papillary carcinomas

artículo científico publicado en 2005

SDHD promoter mutations are rare events in cutaneous melanomas but SDHD protein expression is downregulated in advanced cutaneous melanoma

artículo científico publicado en 2017

STAT3 negatively regulates thyroid tumorigenesis

scientific journal article

Scalp basal cell carcinoma: A different entity?

artículo científico publicado en 2019

Selenium and Selenoproteins in Immune Mediated Thyroid Disorders

artículo científico publicado en 2018

Signet Ring Cell Carcinoma of the Stomach: A Morphometric, Ultrastructural, and DNA Cytometric Study

artículo científico publicado en 1992

Small Cell Tumours

Small papillary thyroid cancers—is BRAF of prognostic value?

artículo científico publicado en 2011

Somatic and germline mutation in GRIM-19, a dual function gene involved in mitochondrial metabolism and cell death, is linked to mitochondrion-rich (Hurthle cell) tumours of the thyroid.

artículo científico publicado en 2005

Sporadic ret-rearranged papillary carcinoma of the thyroid: a subset of slow growing, less aggressive thyroid neoplasms?

artículo científico publicado en 1998

Stimulated thyroglobulin at recombinant human TSH-aided ablation predicts disease-free status one year later

artículo científico publicado en 2013

Survey of 548 oncogenic fusion transcripts in thyroid tumors supports the importance of the already established thyroid fusions genes

artículo científico publicado en 2012

Synergistic growth inhibition of cancer cells harboring the RET/PTC1 oncogene by staurosporine and rotenone involves enhanced cell death.

artículo científico publicado en 2011

TERT Promoter Mutation as a Potential Predictive Biomarker in BCG-Treated Bladder Cancer Patients

artículo científico publicado en 2020

TERT biology and function in cancer: beyond immortalisation

artículo científico publicado en 2017

TERT promoter mutations are a major indicator of poor outcome in differentiated thyroid carcinomas

artículo científico publicado en 2014

TERT promoter mutations are associated with poor prognosis in cutaneous squamous cell carcinoma

scientific article published on 28 August 2018

TERT promoter mutations in pancreatic endocrine tumours are rare and mainly found in tumours from patients with hereditary syndromes

artículo científico publicado en 2016

TERT promoter mutations in skin cancer: the effects of sun exposure and X-irradiation.

artículo científico publicado en 2014

TERT promoter mutations in soft tissue sarcomas.

artículo científico publicado en 2016

TERT promoter mutations: a genetic signature of benign and malignant thyroid tumours occurring in the context of tinea capitis irradiation

artículo científico publicado en 2016

TERT, BRAF, and NRAS in Primary Thyroid Cancer and Metastatic Disease

artículo científico publicado en 2017

TERTp mutation is associated with a shorter progression free survival in patients with aggressive histology subtypes of follicular-cell derived thyroid carcinoma

artículo científico publicado en 2018

TGF-beta/Smad pathway and BRAF mutation play different roles in circumscribed and infiltrative papillary thyroid carcinoma

artículo científico publicado en 2012

Tackling Thyroid Cancer in Europe-The Challenges and Opportunities

artículo científico publicado en 2022

Telomerase Activation in Hematological Malignancies

artículo científico publicado en 2016

Telomerase and N-Cadherin Differential Importance in Adrenocortical Cancers and Adenomas

artículo científico publicado en 2016

Telomerase expression and proliferative activity suggest a stem cell role for thyroid solid cell nests

artículo científico publicado en 2004

Telomerase promoter mutations in cancer: an emerging molecular biomarker?

artículo científico publicado en 2014

Telomere Maintenance Mechanisms in Cancer.

artículo científico publicado en 2018

The Genetics of Papillary Microcarcinomas of the Thyroid: Diagnostic and Prognostic Implications

artículo científico publicado en 2017

The Role of ATRX in the Alternative Lengthening of Telomeres (ALT) Phenotype

artículo científico publicado en 2016

The biology and the genetics of Hurthle cell tumors of the thyroid.

artículo científico publicado en 2012

The environmental contaminant tributyltin leads to abnormalities in different levels of the hypothalamus-pituitary-thyroid axis in female rats

artículo científico publicado en 2018

The genetics of cutaneous squamous cell carcinogenesis

artículo científico publicado en 2018

The mTOR signalling pathway in human cancer

artículo científico publicado en 2012

The p75 neurotrophin receptor is widely expressed in conventional papillary thyroid carcinoma

artículo científico publicado en 2006

The preeminence of growth pattern and invasiveness and the limited influence of BRAF and RAS mutations in the occurrence of papillary thyroid carcinoma lymph node metastases

artículo científico publicado en 2011

The role of ablative treatment in differentiated thyroid cancer management

scientific article published on 10 February 2017

Therapeutic Options

Thyroid and Parathyroid Glands

Thyroid and parathyroid tumours in patients submitted to X-ray scalp epilation during the tinea capitis eradication campaign in the North of Portugal (1950-1963).

artículo científico publicado en 2014

Thyroid hormone as a regulator of tumor induced angiogenesis

artículo científico publicado en 2010

Tributyltin and Zebrafish: Swimming in Dangerous Water.

artículo científico publicado en 2018

Tumor-in-tumor of the thyroid with basaloid differentiation: a lesion with a solid cell nest neoplastic component?

artículo científico publicado en 2011

Type and prevalence of BRAF mutations are closely associated with papillary thyroid carcinoma histotype and patients’ age but not with tumour aggressiveness

artículo científico publicado en 2005

Unraveling molecular targets of bisphenol A and S in the thyroid gland

scientific article published on 13 July 2018

Vascular invasion in thyroid and gastric carcinomas.

artículo científico publicado en 2003

mTOR Pathway in Papillary Thyroid Carcinoma: Different Contributions of mTORC1 and mTORC2 Complexes for Tumor Behavior and SLC5A5 mRNA Expression.

artículo científico publicado en 2018

mTOR activation in medullary thyroid carcinoma with RAS mutation.

artículo científico publicado en 2014

mTOR pathway activation in cutaneous melanoma is associated with poorer prognosis characteristics.

artículo científico publicado en 2010

mTOR pathway overactivation in BRAF mutated papillary thyroid carcinoma.

artículo científico publicado en 2012

p63 expression in solid cell nests of the thyroid: further evidence for a stem cell origin

artículo científico publicado en 2003

pmTOR is a marker of aggressiveness in papillary thyroid carcinomas

artículo científico publicado en 2016

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