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Lista de obras de Shile Huang

A critical role of CDKN3 in Bcr-Abl-mediated tumorigenesis

artículo científico publicado en 2014

A deut of mTORC1/2 for cell adhesion

artículo científico publicado en 2015

A long noncoding RNA critically regulates Bcr-Abl-mediated cellular transformation by acting as a competitive endogenous RNA.

artículo científico publicado en 2014

A new clue to explain resistance to mTOR inhibitors.

artículo científico publicado en 2012

Activation of AMPK and inactivation of Akt result in suppression of mTOR-mediated S6K1 and 4E-BP1 pathways leading to neuronal cell death in in vitro models of Parkinson's disease

artículo científico publicado en 2014

An insight of rapamycin against cadmium's neurotoxicity.

artículo científico publicado en 2017

Artesunate enhances the immune response of rabies vaccine as an adjuvant

scientific article published on 30 September 2019

Avermectin induces P-glycoprotein expression in S2 cells via the calcium/calmodulin/NF-κB pathway

artículo científico publicado en 2013

BAFF activates Erk1/2 promoting cell proliferation and survival by Ca2+-CaMKII-dependent inhibition of PP2A in normal and neoplastic B-lymphoid cells.

artículo científico publicado en 2013

BAFF inhibits autophagy promoting cell proliferation and survival by activating Ca2+-CaMKII-dependent Akt/mTOR signaling pathway in normal and neoplastic B-lymphoid cells

artículo científico publicado en 2018

Biological activities of fusarochromanone: a potent anti-cancer agent

artículo científico publicado en 2014

Both mTORC1 and mTORC2 are involved in the regulation of cell adhesion.

artículo científico publicado en 2015

CaMKII is involved in cadmium activation of MAPK and mTOR pathways leading to neuronal cell death

scientific journal article

Cadmium activates the mitogen-activated protein kinase (MAPK) pathway via induction of reactive oxygen species and inhibition of protein phosphatases 2A and 5

scientific journal article

Cadmium induces mitochondrial ROS inactivation of XIAP pathway leading to apoptosis in neuronal cells

artículo científico publicado en 2020

Cadmium induction of reactive oxygen species activates the mTOR pathway, leading to neuronal cell death

scientific journal article

Cadmium results in accumulation of autophagosomes-dependent apoptosis through activating Akt-impaired autophagic flux in neuronal cells

scientific article published on 19 December 2018

Calcium signaling is involved in cadmium-induced neuronal apoptosis via induction of reactive oxygen species and activation of MAPK/mTOR network.

artículo científico publicado en 2011

Celastrol Attenuates Cadmium-Induced Neuronal Apoptosis via Inhibiting Ca2+ -CaMKII-Dependent Akt/mTOR Pathway

artículo científico publicado en 2016

Celastrol ameliorates Cd-induced neuronal apoptosis by targeting NOX2-derived ROS-dependent PP5-JNK signaling pathway

artículo científico publicado en 2017

Celastrol prevents cadmium-induced neuronal cell death by blocking reactive oxygen species-mediated mammalian target of rapamycin pathway

artículo científico publicado en 2016

Celastrol prevents cadmium-induced neuronal cell death via targeting JNK and PTEN-Akt/mTOR network.

artículo científico publicado en 2013

Ciclopirox activates ATR-Chk1 signaling pathway leading to Cdc25A protein degradation.

artículo científico publicado en 2018

Ciclopirox induces autophagy through reactive oxygen species-mediated activation of JNK signaling pathway

artículo científico publicado en 2014

Ciclopirox inhibits cancer cell proliferation by suppression of Cdc25A.

artículo científico publicado en 2017

Ciclopirox olamine inhibits mTORC1 signaling by activation of AMPK.

artículo científico publicado en 2016

Concerted suppression of STAT3 and GSK3β is involved in growth inhibition of non-small cell lung cancer by Xanthatin

artículo científico publicado en 2013

Correction to: Cryptotanshinone activates AMPK-TSC2 axis leading to inhibition of mTORC1 signaling in cancer cells

artículo científico publicado en 2019

Correction: Suppression of Interferon Lambda Signaling by SOCS-1 Results in Their Excessive Production during Influenza Virus Infection

artículo científico publicado en 2016

Corrigendum to "Maduramicin-activated protein phosphatase 2A results in extracellular signal-regulated kinase 1/2 inhibition, leading to cytotoxicity in myocardial H9c2 cells" [Toxicol. Lett. 284 (2018) 96-102]

scientific article published on 10 September 2018

Crosstalk between Ca2+ signaling and mitochondrial H2O2 is required for rotenone inhibition of mTOR signaling pathway leading to neuronal apoptosis.

artículo científico publicado en 2016

Cryptotanshinone activates p38/JNK and inhibits Erk1/2 leading to caspase-independent cell death in tumor cells

artículo científico publicado en 2012

Cryptotanshinone inhibits cancer cell proliferation by suppressing Mammalian target of rapamycin-mediated cyclin D1 expression and Rb phosphorylation

artículo científico publicado en 2010

Cryptotanshinone inhibits lymphatic endothelial cell tube formation by suppressing VEGFR-3/ERK and small GTPase pathways

artículo científico publicado en 2011

Curcumin disrupts the Mammalian target of rapamycin-raptor complex.

artículo científico publicado en 2009

Curcumin inhibition of integrin (alpha6beta4)-dependent breast cancer cell motility and invasion

artículo científico publicado en 2008

Curcumin inhibits protein phosphatases 2A and 5, leading to activation of mitogen-activated protein kinases and death in tumor cells.

artículo científico publicado en 2012

Curcumin inhibits the mammalian target of rapamycin-mediated signaling pathways in cancer cells

artículo científico publicado en 2006

Current development of the second generation of mTOR inhibitors as anticancer agents

artículo científico publicado en 2011

Dihydroartemisinin inhibits the mammalian target of rapamycin-mediated signaling pathways in tumor cells

scientific article published on 08 August 2013

Downregulation of Integrins in Cancer Cells and Anti-Platelet Properties Are Involved in Holothurian Glycosaminoglycan-Mediated Disruption of the Interaction of Cancer Cells and Platelets in Hematogenous Metastasis

artículo científico publicado en 2015

Editorial [Hot Topic: Novel Protein & Peptide Science (Guest Editor: Shile Huang)]

scientific article published on 01 February 2011

Erratum

scholarly article published in Autophagy

Fisetin, a 3,7,3',4'-Tetrahydroxyflavone Inhibits the PI3K/Akt/mTOR and MAPK Pathways and Ameliorates Psoriasis Pathology in 2D and 3D Organotypic Human Inflammatory Skin Models

scientific article published on 15 September 2019

Fusarochromanone induces G1 cell cycle arrest and apoptosis in COS7 and HEK293 cells

artículo científico publicado en 2014

Fusarochromanone-induced reactive oxygen species results in activation of JNK cascade and cell death by inhibiting protein phosphatases 2A and 5.

artículo científico publicado en 2015

Ganoderma lucidum Polysaccharides as An Anti-cancer Agent

artículo científico publicado en 2017

Hitting the golden TORget: curcumin's effects on mTOR signaling

artículo científico

Host Immune Response to Influenza A Virus Infection.

artículo científico publicado en 2018

Hydrogen peroxide inhibits mTOR signaling by activation of AMPKalpha leading to apoptosis of neuronal cells

artículo científico publicado en 2010

Hydrogen peroxide-induced neuronal apoptosis is associated with inhibition of protein phosphatase 2A and 5, leading to activation of MAPK pathway

scientific journal article

IL-2, IL-4, IFN-γ or TNF-α enhances BAFF-stimulated cell viability and survival by activating Erk1/2 and S6K1 pathways in neoplastic B-lymphoid cells

artículo científico publicado en 2016

Infection of goats with goatpox virus triggers host antiviral defense through activation of innate immune signaling

artículo científico publicado en 2015

Influenza A virus-induced degradation of eukaryotic translation initiation factor 4B contributes to viral replication by suppressing IFITM3 protein expression.

artículo científico publicado en 2014

Inhibition of PI3K/Akt/mTOR signaling by natural products

artículo científico publicado en 2013

Inhibition of mammalian target of rapamycin activates apoptosis signal-regulating kinase 1 signaling by suppressing protein phosphatase 5 activity

artículo científico publicado en 2004

Inhibition of vascular endothelial growth factor-mediated angiogenesis involved in reproductive toxicity induced by sesquiterpenoids of Curcuma zedoaria in rats.

artículo científico publicado en 2013

Inhibitors of mammalian target of rapamycin as novel antitumor agents: from bench to clinic.

artículo científico publicado en 2002

Insulin-like growth factor I-mediated protection from rapamycin-induced apoptosis is independent of Ras-Erk1-Erk2 and phosphatidylinositol 3'-kinase-Akt signaling pathways.

artículo científico publicado en 2003

Interaction of Abl Tyrosine Kinases with SOCS3 Impairs Its Suppressor Function in Tumorigenesis

Iron chelation inhibits mTORC1 signaling involving activation of AMPK and REDD1/Bnip3 pathways

artículo científico publicado en 2020

MAPK and mTOR pathways are involved in cadmium-induced neuronal apoptosis

artículo científico publicado en 2007

Maduramicin inactivation of Akt impairs autophagic flux leading to accumulated autophagosomes-dependent apoptosis in skeletal myoblast cells

scientific article published on 17 July 2019

Maduramicin induces apoptosis and necrosis, and blocks autophagic flux in myocardial H9c2 cells.

artículo científico publicado en 2017

Maduramicin induces apoptosis through ROS-PP5-JNK pathway in skeletal myoblast cells and muscle tissue

scientific article published on 20 June 2019

Maduramicin induces cardiac muscle cell death by the ROS-dependent PTEN/Akt-Erk1/2 signaling pathway

scientific article published on 03 December 2018

Maduramicin inhibits proliferation and induces apoptosis in myoblast cells

artículo científico publicado en 2014

Maduramicin-activated protein phosphatase 2A results in extracellular signal-regulated kinase 1/2 inhibition, leading to cytotoxicity in myocardial H9c2 cells.

artículo científico publicado en 2017

Mechanisms of resistance to rapamycins

artículo científico publicado en 2001

Molecular evidence of cryptotanshinone for treatment and prevention of human cancer

artículo científico publicado en 2013

N-acetyl-L-cysteine protects against cadmium-induced neuronal apoptosis by inhibiting ROS-dependent activation of Akt/mTOR pathway in mouse brain

artículo científico publicado en 2014

Negative regulation of ASK1 by p21Cip1 involves a small domain that includes Serine 98 that is phosphorylated by ASK1 in vivo

artículo científico publicado en 2007

Nitric oxide-mediated cGMP synthesis in Helix neural ganglia.

artículo científico publicado en 1998

Novel lncRNA-IUR suppresses Bcr-Abl-induced tumorigenesis through regulation of STAT5-CD71 pathway

artículo científico publicado en 2019

PKM2 regulates hepatocellular carcinoma cell epithelial-mesenchymal transition and migration upon EGFR activation

artículo científico publicado en 2014

PP2A Level in Colorectal Cancer Cells Predicts the Response of p38 Targeted Therapy

artículo científico publicado en 2015

Rapamycin ameliorates cadmium-induced activation of MAPK pathway and neuronal apoptosis by preventing mitochondrial ROS inactivation of PP2A.

artículo científico publicado en 2016

Rapamycin attenuates BAFF-extended proliferation and survival via disruption of mTORC1/2 signaling in normal and neoplastic B-lymphoid cells

artículo científico publicado en 2017

Rapamycin inhibits B-cell activating factor (BAFF)-stimulated cell proliferation and survival by suppressing Ca2+-CaMKII-dependent PTEN/Akt-Erk1/2 signaling pathway in normal and neoplastic B-lymphoid cells

artículo científico publicado en 2020

Rapamycin inhibits BAFF-stimulated cell proliferation and survival by suppressing mTOR-mediated PP2A-Erk1/2 signaling pathway in normal and neoplastic B-lymphoid cells

artículo científico publicado en 2015

Rapamycin inhibits Erk1/2-mediated neuronal apoptosis caused by cadmium.

artículo científico publicado en 2015

Rapamycin inhibits F-actin reorganization and phosphorylation of focal adhesion proteins

artículo científico publicado en 2008

Rapamycin inhibits IGF-1 stimulated cell motility through PP2A pathway

artículo científico publicado en 2010

Rapamycin inhibits cell motility by suppression of mTOR-mediated S6K1 and 4E-BP1 pathways

artículo científico publicado en 2006

Rapamycin inhibits cytoskeleton reorganization and cell motility by suppressing RhoA expression and activity.

artículo científico publicado en 2010

Rapamycin inhibits lymphatic endothelial cell tube formation by downregulating vascular endothelial growth factor receptor 3 protein expression.

artículo científico publicado en 2012

Rapamycin inhibits mSin1 phosphorylation independently of mTORC1 and mTORC2.

artículo científico publicado en 2015

Rapamycin prevents cadmium-induced neuronal cell death via targeting both mTORC1 and mTORC2 pathways

artículo científico publicado en 2015

Rapamycins: mechanism of action and cellular resistance

artículo científico publicado en 2003

ReishiMax inhibits mTORC1/2 by activating AMPK and inhibiting IGFR/PI3K/Rheb in tumor cells

scientific article published on 28 June 2019

Repositioning the Old Fungicide Ciclopirox for New Medical Uses.

artículo científico publicado en 2016

Resistance to rapamycin: a novel anticancer drug

artículo científico publicado en 2001

Resveratrol inhibits Erk1/2-mediated adhesion of cancer cells via activating PP2A-PTEN signaling network

scientific article published on 01 August 2018

Resveratrol prevents cadmium activation of Erk1/2 and JNK pathways from neuronal cell death via protein phosphatases 2A and 5.

artículo científico publicado en 2015

Rhabdovirus Infection Is Dependent on Serine/Threonine Kinase AP2-Associated Kinase 1

scientific article published on 30 August 2020

Role and Therapeutic Targeting of the PI3K/Akt/mTOR Signaling Pathway in Skin Cancer: A Review of Current Status and Future Trends on Natural and Synthetic Agents Therapy

artículo científico publicado en 2019

Role of mTOR signaling in tumor cell motility, invasion and metastasis

scientific article published on February 2011

Rotenone induction of hydrogen peroxide inhibits mTOR-mediated S6K1 and 4E-BP1/eIF4E pathways, leading to neuronal apoptosis

artículo científico publicado en 2014

SKLB188 inhibits the growth of head and neck squamous cell carcinoma by suppressing EGFR signalling

artículo científico publicado en 2017

Suppression of interferon lambda signaling by SOCS-1 results in their excessive production during influenza virus infection

artículo científico publicado en 2014

Sustained activation of the JNK cascade and rapamycin-induced apoptosis are suppressed by p53/p21(Cip1)

artículo científico publicado en 2003

Targeting mTOR signaling for cancer therapy

artículo científico publicado en 2003

The antitumor activity of the fungicide ciclopirox

artículo científico publicado en 2010

The bromodomain protein BRD4 positively regulates necroptosis via modulating MLKL expression

scientific article published on 15 January 2019

The complexes of mammalian target of rapamycin.

artículo científico publicado en 2010

The fungicide ciclopirox inhibits lymphatic endothelial cell tube formation by suppressing VEGFR-3-mediated ERK signaling pathway

artículo científico publicado en 2011

The role of Cdc25A in the regulation of cell proliferation and apoptosis

scientific journal article

The targets of curcumin.

artículo científico publicado en 2011

Tracing brain genotoxic stress in Parkinson's disease with a novel single-cell genetic sensor

artículo científico publicado en 2022

Understanding of leukemic stem cells and their clinical implications.

artículo científico publicado en 2017

Updates of mTOR inhibitors

artículo científico publicado en 2010

eIF4B is a convergent target and critical effector of oncogenic Pim and PI3K/Akt/mTOR signaling pathways in Abl transformants.

artículo científico publicado en 2016

eIF4B phosphorylation by pim kinases plays a critical role in cellular transformation by Abl oncogenes

artículo científico publicado en 2013

mTOR Signaling in Metabolism and Cancer

artículo científico publicado en 2020

mTOR as a target for cancer therapy.

artículo científico publicado en 2004

p53/p21(CIP1) cooperate in enforcing rapamycin-induced G(1) arrest and determine the cellular response to rapamycin.

artículo científico publicado en 2001

α-Synuclein disrupts stress signaling by inhibiting polo-like kinase Cdc5/Plk2

artículo científico publicado en 2012

Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition)

artículo científico publicado en 2016