Lista de obras - Graham R. Leggatt - Dominio Público Uruguay

A combination of local inflammation and central memory T cells potentiates immunotherapy in the skin

artículo científico publicado en 2012

Antigen-specific CD4 cells assist CD8 T-effector cells in eliminating keratinocytes.

artículo científico publicado en 2010

Changes to peptide structure, not concentration, contribute to expansion of the lowest avidity cytotoxic T lymphocytes

artículo científico publicado en 2004

Chimeric human papilloma virus-simian/human immunodeficiency virus virus-like-particle vaccines: immunogenicity and protective efficacy in macaques

artículo científico publicado en 2002

Cytotoxic T lymphocyte (CTL) adherence assay (CAA): a non-radioactive assay for murine CTL recognition of peptide-MHC class I complexes

artículo científico publicado en 1997

Elevated frequencies of CD8 T cells expressing PD-1, CTLA-4 and Tim-3 within tumour from perineural squamous cell carcinoma patients

artículo científico publicado en 2017

Enhanced tumor growth in the NaS1 sulfate transporter null mouse

artículo científico publicado en 2009

Epithelial expression of human papillomavirus type 16 E7 protein results in peripheral CD8 T-cell suppression mediated by CD4+CD25+ T cells

artículo científico publicado en 2009

Expression of a single, viral oncoprotein in skin epithelium is sufficient to recruit lymphocytes

artículo científico publicado en 2013

Expression of the HPV16E7 oncoprotein by thymic epithelium is accompanied by disrupted T cell maturation and a failure of the thymus to involute with age

artículo científico publicado en 2003

Functional memory CD8+ T cells can be generated in vivo without evident T help

scientific article published on 01 December 2004

Further characterization of the 38 kDa antigen from Echinococcus granulosus (hydatid disease) cyst fluid: evidence for antigenic heterogeneity and reactivity with anti-P1 antibodies

scientific article published on 01 June 1995

HPV vaccines: the beginning of the end for cervical cancer.

artículo científico publicado en 2007

HPV16 E7-Driven Epithelial Hyperplasia Promotes Impaired Antigen Presentation and Regulatory T-Cell Development

artículo científico publicado en 2019

HPV16-E7 expression in squamous epithelium creates a local immune suppressive environment via CCL2- and CCL5- mediated recruitment of mast cells

artículo científico publicado en 2014

Histone deacetylase inhibitors in the generation of the anti-tumour immune response

artículo científico publicado en 2011

Human growth hormone presented by K14hGH-transgenic skin grafts induces a strong immune response but no graft rejection

scientific article published on 01 December 2004

Human papillomavirus 16 E7 protein inhibits interferon-γ-mediated enhancement of keratinocyte antigen processing and T-cell lysis

artículo científico publicado en 2011

Hydatid immunoblot test and cross-reactivity with sera from patients with cysticercosis

scientific article published on 01 May 1993

IFN-gamma promotes generation of IL-10 secreting CD4+ T cells that suppress generation of CD8 responses in an antigen-experienced host

artículo científico publicado en 2009

IL-1 signalling determines the fate of skin grafts expressing non-self protein in keratinocytes

artículo científico publicado en 2010

Immunosuppressive roles of natural killer T (NKT) cells in the skin

artículo científico publicado en 2014

Impact of sex steroid ablation on viral, tumour and vaccine responses in aged mice.

artículo científico publicado en 2012

Impaired Antigen Presentation and Effectiveness of Combined Active/Passive Immunotherapy for Epithelial Tumors

artículo científico publicado en 2004

Indoleamine 2,3-dioxygenase activity contributes to local immune suppression in the skin expressing human papillomavirus oncoprotein e7.

artículo científico publicado en 2013

Inhibition of cervical cancer cell growth in vitro and in vivo with lentiviral-vector delivered short hairpin RNA targeting human papillomavirus E6 and E7 oncogenes.

artículo científico publicado en 2006

Interferon-gamma enhances cytotoxic T lymphocyte recognition of endogenous peptide in keratinocytes without lowering the requirement for surface peptide

artículo científico publicado en 2002

Invariant NKT Cells in Hyperplastic Skin Induce a Local Immune Suppressive Environment by IFN- Production

artículo científico publicado en 2009

Keratinocytes efficiently process endogenous antigens for cytotoxic T-cell mediated lysis.

artículo científico publicado en 2009

Modulation of antigen presenting cell functions during chronic HPV infection.

artículo científico publicado en 2017

NKT Cell-Driven Enhancement of Antitumor Immunity Induced by Clec9a-Targeted Tailorable Nanoemulsion

artículo científico publicado en 2019

NKT cells inhibit antigen-specific effector CD8 T cell induction to skin viral proteins.

artículo científico publicado en 2011

Nonspecific down-regulation of CD8+ T-cell responses in mice expressing human papillomavirus type 16 E7 oncoprotein from the keratin-14 promoter.

artículo científico publicado en 2001

Papillomavirus virus-like particles for the delivery of multiple cytotoxic T cell epitopes

artículo científico publicado en 2000

Paucity of functional CTL epitopes in the E7 oncoprotein of cervical cancer associated human papillomavirus type 16

artículo científico publicado en 2003

Peptide Dose and/or Structure in Vaccines as a Determinant of T Cell Responses

artículo científico

Polynucleotide viral vaccines: codon optimisation and ubiquitin conjugation enhances prophylactic and therapeutic efficacy.

artículo científico publicado en 2001

Prevention and Treatment of Papillomavirus-Related Cancers Through Immunization ⬇️

artículo científico publicado el 1 de enero de 2011

RNA interference against human papillomavirus oncogenes in cervical cancer cells results in increased sensitivity to cisplatin.

artículo científico publicado en 2005

Recent progress in vaccination against human papillomavirus-mediated cervical cancer

artículo científico publicado en 2015

Regulation of immune responses to HPV infection and during HPV-directed immunotherapy

artículo científico publicado en 2011

Role of intratumoural heterogeneity in cancer drug resistance: molecular and clinical perspectives

artículo científico publicado en 2012

Route of administration of chimeric BPV1 VLP determines the character of the induced immune responses

article

Secondary immunisation with high-dose heterologous peptide leads to CD8 T cell populations with reduced functional avidity

artículo científico publicado en 2007

Secretion of IFN-gamma but not IL-17 by CD1d-restricted NKT cells enhances rejection of skin grafts expressing epithelial cell-derived antigen

artículo científico publicado en 2010

Selective expansion of high- or low-avidity cytotoxic T lymphocytes and efficacy for adoptive immunotherapy.

artículo científico publicado en 1996

Sequence homology between two immunodiagnostic fusion proteins from Echinococcus multilocularis

artículo científico publicado en 1992

Serological evaluation of the 12 kDa subunit of antigen B in Echinococcus granulosus cyst fluid by immunoblot analysis

artículo científico publicado en 1992

Split tolerance to a viral antigen expressed in thymic epithelium and keratinocytes

article

TLR7 stimulation augments T effector-mediated rejection of skin expressing neo-self antigen in keratinocytes

artículo científico publicado en 2008

The kinematics of cytotoxic lymphocytes influence their ability to kill target cells

artículo científico publicado en 2014

The number of long-lasting functional memory CD8+ T cells generated depends on the nature of the initial nonspecific stimulation.

artículo científico publicado en 2002

Tumour susceptibility to innate and adaptive immunotherapy changes during tumour maturation.

artículo científico publicado en 2004

γδ T cells augment rejection of skin grafts by enhancing cross-priming of CD8 T cells to skin-derived antigen

artículo científico publicado en 2012

Lista de obras de Graham R. Leggatt

A combination of local inflammation and central memory T cells potentiates immunotherapy in the skin

Antigen-specific CD4 cells assist CD8 T-effector cells in eliminating keratinocytes.

Changes to peptide structure, not concentration, contribute to expansion of the lowest avidity cytotoxic T lymphocytes

Chimeric human papilloma virus-simian/human immunodeficiency virus virus-like-particle vaccines: immunogenicity and protective efficacy in macaques

Cytotoxic T lymphocyte (CTL) adherence assay (CAA): a non-radioactive assay for murine CTL recognition of peptide-MHC class I complexes

Elevated frequencies of CD8 T cells expressing PD-1, CTLA-4 and Tim-3 within tumour from perineural squamous cell carcinoma patients

Enhanced tumor growth in the NaS1 sulfate transporter null mouse

Epithelial expression of human papillomavirus type 16 E7 protein results in peripheral CD8 T-cell suppression mediated by CD4+CD25+ T cells

Expression of a single, viral oncoprotein in skin epithelium is sufficient to recruit lymphocytes

Expression of the HPV16E7 oncoprotein by thymic epithelium is accompanied by disrupted T cell maturation and a failure of the thymus to involute with age

Functional memory CD8+ T cells can be generated in vivo without evident T help

Further characterization of the 38 kDa antigen from Echinococcus granulosus (hydatid disease) cyst fluid: evidence for antigenic heterogeneity and reactivity with anti-P1 antibodies

HPV vaccines: the beginning of the end for cervical cancer.

HPV16 E7-Driven Epithelial Hyperplasia Promotes Impaired Antigen Presentation and Regulatory T-Cell Development

HPV16-E7 expression in squamous epithelium creates a local immune suppressive environment via CCL2- and CCL5- mediated recruitment of mast cells

Histone deacetylase inhibitors in the generation of the anti-tumour immune response

Human growth hormone presented by K14hGH-transgenic skin grafts induces a strong immune response but no graft rejection

Human papillomavirus 16 E7 protein inhibits interferon-γ-mediated enhancement of keratinocyte antigen processing and T-cell lysis

Hydatid immunoblot test and cross-reactivity with sera from patients with cysticercosis

IFN-gamma promotes generation of IL-10 secreting CD4+ T cells that suppress generation of CD8 responses in an antigen-experienced host

IL-1 signalling determines the fate of skin grafts expressing non-self protein in keratinocytes

Immunosuppressive roles of natural killer T (NKT) cells in the skin

Impact of sex steroid ablation on viral, tumour and vaccine responses in aged mice.

Impaired Antigen Presentation and Effectiveness of Combined Active/Passive Immunotherapy for Epithelial Tumors

Indoleamine 2,3-dioxygenase activity contributes to local immune suppression in the skin expressing human papillomavirus oncoprotein e7.

Inhibition of cervical cancer cell growth in vitro and in vivo with lentiviral-vector delivered short hairpin RNA targeting human papillomavirus E6 and E7 oncogenes.

Interferon-gamma enhances cytotoxic T lymphocyte recognition of endogenous peptide in keratinocytes without lowering the requirement for surface peptide

Invariant NKT Cells in Hyperplastic Skin Induce a Local Immune Suppressive Environment by IFN- Production

Keratinocytes efficiently process endogenous antigens for cytotoxic T-cell mediated lysis.

Modulation of antigen presenting cell functions during chronic HPV infection.

NKT Cell-Driven Enhancement of Antitumor Immunity Induced by Clec9a-Targeted Tailorable Nanoemulsion

NKT cells inhibit antigen-specific effector CD8 T cell induction to skin viral proteins.

Nonspecific down-regulation of CD8+ T-cell responses in mice expressing human papillomavirus type 16 E7 oncoprotein from the keratin-14 promoter.

Papillomavirus virus-like particles for the delivery of multiple cytotoxic T cell epitopes

Paucity of functional CTL epitopes in the E7 oncoprotein of cervical cancer associated human papillomavirus type 16

Peptide Dose and/or Structure in Vaccines as a Determinant of T Cell Responses

Polynucleotide viral vaccines: codon optimisation and ubiquitin conjugation enhances prophylactic and therapeutic efficacy.

Prevention and Treatment of Papillomavirus-Related Cancers Through Immunization ⬇️

RNA interference against human papillomavirus oncogenes in cervical cancer cells results in increased sensitivity to cisplatin.

Recent progress in vaccination against human papillomavirus-mediated cervical cancer

Regulation of immune responses to HPV infection and during HPV-directed immunotherapy

Role of intratumoural heterogeneity in cancer drug resistance: molecular and clinical perspectives

Route of administration of chimeric BPV1 VLP determines the character of the induced immune responses

Secondary immunisation with high-dose heterologous peptide leads to CD8 T cell populations with reduced functional avidity

Secretion of IFN-gamma but not IL-17 by CD1d-restricted NKT cells enhances rejection of skin grafts expressing epithelial cell-derived antigen

Selective expansion of high- or low-avidity cytotoxic T lymphocytes and efficacy for adoptive immunotherapy.

Sequence homology between two immunodiagnostic fusion proteins from Echinococcus multilocularis

Serological evaluation of the 12 kDa subunit of antigen B in Echinococcus granulosus cyst fluid by immunoblot analysis

Split tolerance to a viral antigen expressed in thymic epithelium and keratinocytes

TLR7 stimulation augments T effector-mediated rejection of skin expressing neo-self antigen in keratinocytes

The kinematics of cytotoxic lymphocytes influence their ability to kill target cells

The number of long-lasting functional memory CD8+ T cells generated depends on the nature of the initial nonspecific stimulation.

Tumour susceptibility to innate and adaptive immunotherapy changes during tumour maturation.

γδ T cells augment rejection of skin grafts by enhancing cross-priming of CD8 T cells to skin-derived antigen