Lista de obras - Tomás Sobrino - Dominio Público Uruguay

A chronic treatment with CDP-choline improves functional recovery and increases neuronal plasticity after experimental stroke.

artículo científico publicado en 2007

A higher body temperature is associated with haemorrhagic transformation in patients with acute stroke untreated with recombinant tissue-type plasminogen activator (rtPA).

artículo científico publicado en 2012

A novel mechanism of neuroprotection: Blood glutamate grabber

artículo científico

Association between neuroserpin and molecular markers of brain damage in patients with acute ischemic stroke

artículo científico publicado en 2011

Association of growth factors with arterial recanalization and clinical outcome in patients with ischemic stroke treated with tPA

artículo científico publicado en 2010

Blood glutamate EAAT2-cell grabbing therapy in cerebral ischemia

artículo científico publicado en 2018

Blood glutamate grabbing does not reduce the hematoma in an intracerebral hemorrhage model but it is a safe excitotoxic treatment modality.

artículo científico publicado en 2015

Blood levels of glutamate oxaloacetate transaminase are more strongly associated with good outcome in acute ischaemic stroke than glutamate pyruvate transaminase levels

artículo científico publicado en 2011

CDP-choline treatment increases circulating endothelial progenitor cells in acute ischemic stroke.

artículo científico publicado en 2011

CGRP and PTX3 as Predictors of Efficacy of Onabotulinumtoxin Type A in Chronic Migraine: An Observational Study.

artículo científico publicado en 2017

CM352 Reduces Brain Damage and Improves Functional Recovery in a Rat Model of Intracerebral Hemorrhage.

artículo científico publicado en 2017

Cd34+ progenitor cells likely are involved in the good functional recovery after intracerebral hemorrhage in humans

artículo científico publicado en 2011

Central nicotine induces browning through hypothalamic κ opioid receptor

artículo científico publicado en 2019

Chronic periodontitis is associated with lacunar infarct: a case-control study

artículo científico publicado en 2016

Clinical validation of blood/brain glutamate grabbing in acute ischemic stroke

scientific article published on 22 August 2018

Corneal and conjunctival alteration of innate immune expression in first-degree relatives of keratoconus patients

scientific article published on 19 September 2020

Delayed post-ischemic administration of CDP-choline increases EAAT2 association to lipid rafts and affords neuroprotection in experimental stroke.

artículo científico publicado en 2007

Early biomarkers of clinical-diffusion mismatch in acute ischemic stroke

artículo científico publicado en 2011

Easy and Efficient Cell Tagging with Block Copolymer-Based Contrast Agents for Sensitive MRI Detection in Vivo

artículo científico publicado en 2016

Endothelial Progenitor Cells as a Therapeutic Approach for Intracerebral Hemorrhage

artículo científico publicado en 2016

Endothelial progenitor cells as a therapeutic option in intracerebral hemorrhage

artículo científico

Endothelial progenitor cells: a new key for endothelial dysfunction in migraine

artículo científico publicado en 2012

Generation and characterization of the human iPSC line IDISi001-A isolated from blood cells of a CADASIL patient carrying a NOTCH3 mutation.

artículo científico publicado en 2018

Glutamate neurotoxicity is involved in the neurological damage in patients undergoing extracorporeal circulation

artículo científico publicado en 2014

Glutamate oxaloacetate transaminase: a new key in the dysregulation of glutamate in migraine patients

artículo científico publicado en 2013

Heads and Tails of Natriuretic Peptides: Neuroprotective Role of Brain Natriuretic Peptide

artículo científico publicado en 2017

Hepatic damage and glutamate oxaloacetate transaminase elevations during fetal asphyxia

artículo científico publicado en 2017

High blood glutamate oxaloacetate transaminase levels are associated with good functional outcome in acute ischemic stroke.

artículo científico publicado en 2011

High blood pressure and inflammation are associated with poor prognosis in lacunar infarctions

artículo científico publicado en 2006

High plasma glutamate concentrations are associated with infarct growth in acute ischemic stroke.

artículo científico publicado en 2008

High pro-BNP levels predict the occurrence of atrial fibrillation after cryptogenic stroke

artículo científico publicado en 2013

High serum levels of endothelin-1 predict severe cerebral edema in patients with acute ischemic stroke treated with t-PA

artículo científico publicado en 2008

High serum levels of growth factors are associated with good outcome in intracerebral hemorrhage.

artículo científico publicado en 2009

High serum levels of leptin are associated with post-stroke depression.

artículo científico publicado en 2009

High serum levels of pro-brain natriuretic peptide (pro BNP) identify cardioembolic origin in undetermined stroke.

artículo científico publicado en 2009

Higher Expression of Toll-Like Receptors 2 and 4 in Blood Cells of Keratoconus Patiens

artículo científico publicado en 2017

Human recombinant glutamate oxaloacetate transaminase 1 (GOT1) supplemented with oxaloacetate induces a protective effect after cerebral ischemia

artículo científico publicado en 2014

Hyperthermia in human ischemic and hemorrhagic stroke: similar outcome, different mechanisms

artículo científico publicado en 2013

Hyperthermia is a surrogate marker of inflammation-mediated cause of brain damage in acute ischaemic stroke.

artículo científico publicado en 2006

Hypothalamic AMPK-ER Stress-JNK1 Axis Mediates the Central Actions of Thyroid Hormones on Energy Balance.

artículo científico publicado en 2017

Impact of benzodiazepines on brain FDG-PET quantification after single-dose and chronic administration in rats.

artículo científico publicado en 2016

In vivo theranostics at the peri-infarct region in cerebral ischemia.

artículo científico publicado en 2013

In vivo ultrasound-activated delivery of recombinant tissue plasminogen activator from the cavity of sub-micrometric capsules

scientific article published on 13 July 2019

Inclusion criteria update for the rat intraluminal ischaemic model for preclinical studies.

artículo científico publicado en 2017

Increased Endothelial Progenitor Cell Levels are Associated with Good Outcome in Intracerebral Hemorrhage

artículo científico publicado en 2016

Increased body iron stores are associated with poor outcome after thrombolytic treatment in acute stroke.

artículo científico publicado en 2006

Increased expression of Toll-like receptors 2 and 4 is associated with poor outcome in intracerebral hemorrhage

artículo científico publicado en 2012

Increased levels of circulating endothelial progenitor cells in patients with ischaemic stroke treated with statins during acute phase

artículo científico publicado en 2012

Inflammation markers and prediction of post-stroke vascular disease recurrence: the MITICO study.

artículo científico publicado en 2009

Inflammation, edema and poor outcome are associated with hyperthermia in hypertensive intracerebral hemorrhages

artículo científico publicado en 2018

Inflammatory and neuroimmunomodulatory changes in acute cerebral ischemia.

scientific article published on 03 April 2009

Influence of the separation procedure on the properties of magnetic nanoparticles: Gaining in vitro stability and T1–T2 magnetic resonance imaging performance

artículo científico publicado en 2016

Innate Immunity Biomarkers for Early Detection of Keratoconus

artículo científico publicado en 2018

Interleukin-10 facilitates the selection of patients for systemic thrombolysis.

artículo científico publicado en 2013

Intraarterial route increases the risk of cerebral lesions after mesenchymal cell administration in animal model of ischemia

artículo científico publicado en 2017

Iron Deposits in Periaqueductal Gray Matter Are Associated with Poor Response to OnabotulinumtoxinA in Chronic Migraine

artículo científico publicado en 2020

Iron deposition in periaqueductal gray matter as a potential biomarker for chronic migraine

artículo científico publicado en 2019

Iron-related brain damage in patients with intracerebral hemorrhage

artículo científico publicado en 2010

Ischemic preconditioning: a novel target for neuroprotective therapy

artículo científico publicado en 2006

Light-Emitting Diode Photobiomodulation After Cerebral Ischemia

artículo científico publicado en 2019

Low Levels of Caveolin-1 Predict Symptomatic Bleeding After Thrombolytic Therapy in Patients With Acute Ischemic Stroke

artículo científico publicado en 2018

Magnetite Nanoparticles for Stem Cell Labeling with High Efficiency and Long-Term in Vivo Tracking

artículo científico publicado en 2016

Micro- and macroalbuminuria predict hemorrhagic transformation in acute ischemic stroke.

artículo científico publicado en 2006

Microbleed burden and hematoma expansion in acute intracerebral hemorrhage

artículo científico publicado en 2013

Mmp-9 immunoreactivity in acute migraine

artículo científico publicado en 2007

Model of Disc Degeneration in Rat Tail Induced Through a Vascular Isolation of Vertebral Endplates

artículo científico publicado en 2017

Multifunctional Superparamagnetic Stiff Nanoreservoirs for Blood Brain Barrier Applications

artículo científico publicado en 2019

NT-pro-BNP: A novel predictor of stroke risk after transient ischemic attack

scientific article published on 20 June 2019

Neovascularization and functional recovery after intracerebral hemorrhage is conditioned by the Tp53 Arg72Pro single-nucleotide polymorphism

artículo científico publicado en 2016

Neuronal excitotoxicity after carotid angioplasty and stent placement procedures

artículo científico publicado en 2013

Neuroplasticity and cellular therapy in cerebral infarction.

artículo científico publicado en 2007

Neuroprotection afforded by antagonists of endothelin-1 receptors in experimental stroke

artículo científico publicado en 2012

Neuroprotection by glutamate oxaloacetate transaminase in ischemic stroke: an experimental study

artículo científico publicado en 2011

Neuroprotective effect of neuroserpin in rat primary cortical cultures after oxygen and glucose deprivation and tPA.

artículo científico publicado en 2010

Neuroprotective effects of dexmedetomidine conditioning strategies: Evidences from an in vitro model of cerebral ischemia

artículo científico publicado en 2015

Neurorepair versus neuroprotection in stroke.

artículo científico publicado en 2006

Obesity Paradox in Ischemic Stroke: Clinical and Molecular Insights

scientific article published on 13 April 2019

Oxaloacetate: a novel neuroprotective for acute ischemic stroke

artículo científico publicado en 2011

Periodontal inflammation is related to increased serum calcitonin gene-related peptide levels in patients with chronic migraine

artículo científico publicado en 2019

Periodontitis and vascular inflammatory biomarkers: an experimental in vivo study in rats

artículo científico publicado en 2019

Periodontitis as a risk indicator and predictor of poor outcome for lacunar infarct

artículo científico publicado en 2018

Periodontitis is associated with systemic inflammation and vascular endothelial dysfunction in patients with lacunar infarct

artículo científico publicado en 2018

Plasma beta-amyloid 1-40 is associated with the diffuse small vessel disease subtype.

artículo científico publicado en 2009

Platelet derived growth factor-CC isoform is associated with hemorrhagic transformation in ischemic stroke patients treated with tissue plasminogen activator.

artículo científico publicado en 2012

Porphyromonas gingivalis lipopolysaccharide-induced periodontitis and serum amyloid-beta peptides

scientific article published on 16 January 2019

Positron Emission Tomography for the Development and Characterization of Corneal Permanence of Ophthalmic Pharmaceutical Formulations.

artículo científico publicado en 2017

Potential protective role of endogenous glutamate-oxaloacetate transaminase against glutamate excitotoxicity in fetal hypoxic-ischaemic asphyxia

artículo científico publicado en 2015

Prestroke physical activity is associated with good functional outcome and arterial recanalization after stroke due to a large vessel occlusion

artículo científico publicado en 2014

Prognostic value of blood interleukin-6 in the prediction of functional outcome after stroke: a systematic review and meta-analysis.

artículo científico

Protective Effects and Magnetic Resonance Imaging Temperature Mapping of Systemic and Focal Hypothermia in Cerebral Ischemia.

artículo científico publicado en 2016

Proteomic analysis shows differential protein expression in endothelial progenitor cells between healthy subjects and ischemic stroke patients.

artículo científico publicado en 2011

Quick adjustment of imaging tracer payload, for in vivo applications of theranostic nanostructures in the brain.

artículo científico publicado en 2013

RP11-362K2.2:RP11-767I20.1 Genetic Variation Is Associated with Post-Reperfusion Therapy Parenchymal Hematoma. A GWAS Meta-Analysis

artículo científico publicado en 2021

Reported Prestroke Physical Activity Is Associated with Vascular Endothelial Growth Factor Expression and Good Outcomes after Stroke

artículo científico publicado en 2016

Role of adipocytokines in the pathophysiology of migraine. A cross-sectional study

artículo científico publicado en 2017

Role of adipocytokines in the pathophysiology of migraine. A cross-sectional study.

artículo científico publicado en 2017

Serum cellular fibronectin and matrix metalloproteinase-9 as screening biomarkers for the prediction of parenchymal hematoma after thrombolytic therapy in acute ischemic stroke: a multicenter confirmatory study.

artículo científico publicado en 2007

Severe periodontitis is linked with increased peripheral levels of sTWEAK and PTX3 in chronic migraineurs

artículo científico publicado en 2019

Single-Nucleotide Polymorphism 309T>G in the MDM2 Promoter Determines Functional Outcome After Stroke

scientific article published on 01 October 2018

Statins and stroke

scientific article published on 01 June 2008

Stroke with polyvascular atherothrombotic disease

artículo científico publicado en 2009

Study of Protein Expression in Peri-Infarct Tissue after Cerebral Ischemia.

artículo científico publicado en 2015

Subclinical keratoconus and inflammatory molecules from tears.

artículo científico publicado en 2009

Targeting the ischemic penumbra

scientific article published on 16 December 2010

Tear film inflammatory mediators during continuous wear of contact lenses and corneal refractive therapy

artículo científico publicado en 2012

Temperature-Induced Changes in Reperfused Stroke: Inflammatory and Thrombolytic Biomarkers

artículo científico publicado en 2020

Temporal profile and clinical significance of serum neuron-specific enolase and S100 in ischemic and hemorrhagic stroke

artículo científico publicado en 2009

Temporal profile of molecular signatures associated with circulating endothelial progenitor cells in human ischemic stroke

artículo científico publicado en 2012

The Increase of Circulating Endothelial Progenitor Cells After Acute Ischemic Stroke Is Associated With Good Outcome

artículo científico publicado en 2007

The effect of simvastatin on the proteome of detergent-resistant membrane domains: decreases of specific proteins previously related to cytoskeleton regulation, calcium homeostasis and cell fate.

artículo científico publicado en 2010

The human Tp53 Arg72Pro polymorphism explains different functional prognosis in stroke. ⬇️

artículo científico publicado en 2011

The natural tissue plasminogen activator inhibitor neuroserpin and acute ischaemic stroke outcome

artículo científico publicado en 2010

The role of angiogenesis in damage and recovery from ischemic stroke

artículo científico publicado en 2007

Toll-like receptors 2 and 4 in ischemic stroke: outcome and therapeutic values

artículo científico publicado en 2011

Toll-like receptors 7 and 8 expression is associated with poor outcome and greater inflammatory response in acute ischemic stroke

scientific article published on 26 February 2011

Trends in stroke outcomes in the last ten years in a European tertiary hospital

artículo científico publicado en 2018

Usefulness of haptoglobin and serum amyloid A proteins as biomarkers for atherothrombotic ischemic stroke diagnosis confirmation

artículo científico publicado en 2008

Vectorized nanodelivery systems for ischemic stroke: a concept and a need.

artículo científico publicado en 2017

White matter injury restoration after stem cell administration in subcortical ischemic stroke

artículo científico publicado en 2015

Worse Outcome in Stroke Patients Treated with rt-PA Without Early Reperfusion: Associated Factors

artículo científico publicado en 2017

[18F]-FMISO PET/MRI Imaging Shows Ischemic Tissue around Hematoma in Intracerebral Hemorrhage

artículo científico publicado en 2020

dsRNAi-mediated silencing of PIAS2beta specifically kills anaplastic carcinomas by mitotic catastrophe

artículo científico publicado en 2024

proMetalloproteinase-10 is associated with brain damage and clinical outcome in acute ischemic stroke.

artículo científico publicado en 2013

Lista de obras de Tomás Sobrino

A chronic treatment with CDP-choline improves functional recovery and increases neuronal plasticity after experimental stroke.

A higher body temperature is associated with haemorrhagic transformation in patients with acute stroke untreated with recombinant tissue-type plasminogen activator (rtPA).

A novel mechanism of neuroprotection: Blood glutamate grabber

Association between neuroserpin and molecular markers of brain damage in patients with acute ischemic stroke

Association of growth factors with arterial recanalization and clinical outcome in patients with ischemic stroke treated with tPA

Blood glutamate EAAT2-cell grabbing therapy in cerebral ischemia

Blood glutamate grabbing does not reduce the hematoma in an intracerebral hemorrhage model but it is a safe excitotoxic treatment modality.

Blood levels of glutamate oxaloacetate transaminase are more strongly associated with good outcome in acute ischaemic stroke than glutamate pyruvate transaminase levels

CDP-choline treatment increases circulating endothelial progenitor cells in acute ischemic stroke.

CGRP and PTX3 as Predictors of Efficacy of Onabotulinumtoxin Type A in Chronic Migraine: An Observational Study.

CM352 Reduces Brain Damage and Improves Functional Recovery in a Rat Model of Intracerebral Hemorrhage.

Cd34+ progenitor cells likely are involved in the good functional recovery after intracerebral hemorrhage in humans

Central nicotine induces browning through hypothalamic κ opioid receptor

Chronic periodontitis is associated with lacunar infarct: a case-control study

Clinical validation of blood/brain glutamate grabbing in acute ischemic stroke

Corneal and conjunctival alteration of innate immune expression in first-degree relatives of keratoconus patients

Delayed post-ischemic administration of CDP-choline increases EAAT2 association to lipid rafts and affords neuroprotection in experimental stroke.

Early biomarkers of clinical-diffusion mismatch in acute ischemic stroke

Easy and Efficient Cell Tagging with Block Copolymer-Based Contrast Agents for Sensitive MRI Detection in Vivo

Endothelial Progenitor Cells as a Therapeutic Approach for Intracerebral Hemorrhage

Endothelial progenitor cells as a therapeutic option in intracerebral hemorrhage

Endothelial progenitor cells: a new key for endothelial dysfunction in migraine

Generation and characterization of the human iPSC line IDISi001-A isolated from blood cells of a CADASIL patient carrying a NOTCH3 mutation.

Glutamate neurotoxicity is involved in the neurological damage in patients undergoing extracorporeal circulation

Glutamate oxaloacetate transaminase: a new key in the dysregulation of glutamate in migraine patients

Heads and Tails of Natriuretic Peptides: Neuroprotective Role of Brain Natriuretic Peptide

Hepatic damage and glutamate oxaloacetate transaminase elevations during fetal asphyxia

High blood glutamate oxaloacetate transaminase levels are associated with good functional outcome in acute ischemic stroke.

High blood pressure and inflammation are associated with poor prognosis in lacunar infarctions

High plasma glutamate concentrations are associated with infarct growth in acute ischemic stroke.

High pro-BNP levels predict the occurrence of atrial fibrillation after cryptogenic stroke

High serum levels of endothelin-1 predict severe cerebral edema in patients with acute ischemic stroke treated with t-PA

High serum levels of growth factors are associated with good outcome in intracerebral hemorrhage.

High serum levels of leptin are associated with post-stroke depression.

High serum levels of pro-brain natriuretic peptide (pro BNP) identify cardioembolic origin in undetermined stroke.

Higher Expression of Toll-Like Receptors 2 and 4 in Blood Cells of Keratoconus Patiens

Human recombinant glutamate oxaloacetate transaminase 1 (GOT1) supplemented with oxaloacetate induces a protective effect after cerebral ischemia

Hyperthermia in human ischemic and hemorrhagic stroke: similar outcome, different mechanisms

Hyperthermia is a surrogate marker of inflammation-mediated cause of brain damage in acute ischaemic stroke.

Hypothalamic AMPK-ER Stress-JNK1 Axis Mediates the Central Actions of Thyroid Hormones on Energy Balance.

Impact of benzodiazepines on brain FDG-PET quantification after single-dose and chronic administration in rats.

In vivo theranostics at the peri-infarct region in cerebral ischemia.

In vivo ultrasound-activated delivery of recombinant tissue plasminogen activator from the cavity of sub-micrometric capsules

Inclusion criteria update for the rat intraluminal ischaemic model for preclinical studies.

Increased Endothelial Progenitor Cell Levels are Associated with Good Outcome in Intracerebral Hemorrhage

Increased body iron stores are associated with poor outcome after thrombolytic treatment in acute stroke.

Increased expression of Toll-like receptors 2 and 4 is associated with poor outcome in intracerebral hemorrhage

Increased levels of circulating endothelial progenitor cells in patients with ischaemic stroke treated with statins during acute phase

Inflammation markers and prediction of post-stroke vascular disease recurrence: the MITICO study.

Inflammation, edema and poor outcome are associated with hyperthermia in hypertensive intracerebral hemorrhages

Inflammatory and neuroimmunomodulatory changes in acute cerebral ischemia.

Influence of the separation procedure on the properties of magnetic nanoparticles: Gaining in vitro stability and T1–T2 magnetic resonance imaging performance

Innate Immunity Biomarkers for Early Detection of Keratoconus

Interleukin-10 facilitates the selection of patients for systemic thrombolysis.

Intraarterial route increases the risk of cerebral lesions after mesenchymal cell administration in animal model of ischemia

Iron Deposits in Periaqueductal Gray Matter Are Associated with Poor Response to OnabotulinumtoxinA in Chronic Migraine

Iron deposition in periaqueductal gray matter as a potential biomarker for chronic migraine

Iron-related brain damage in patients with intracerebral hemorrhage

Ischemic preconditioning: a novel target for neuroprotective therapy

Light-Emitting Diode Photobiomodulation After Cerebral Ischemia

Low Levels of Caveolin-1 Predict Symptomatic Bleeding After Thrombolytic Therapy in Patients With Acute Ischemic Stroke

Magnetite Nanoparticles for Stem Cell Labeling with High Efficiency and Long-Term in Vivo Tracking

Micro- and macroalbuminuria predict hemorrhagic transformation in acute ischemic stroke.

Microbleed burden and hematoma expansion in acute intracerebral hemorrhage

Mmp-9 immunoreactivity in acute migraine

Model of Disc Degeneration in Rat Tail Induced Through a Vascular Isolation of Vertebral Endplates

Multifunctional Superparamagnetic Stiff Nanoreservoirs for Blood Brain Barrier Applications

NT-pro-BNP: A novel predictor of stroke risk after transient ischemic attack

Neovascularization and functional recovery after intracerebral hemorrhage is conditioned by the Tp53 Arg72Pro single-nucleotide polymorphism

Neuronal excitotoxicity after carotid angioplasty and stent placement procedures

Neuroplasticity and cellular therapy in cerebral infarction.

Neuroprotection afforded by antagonists of endothelin-1 receptors in experimental stroke

Neuroprotection by glutamate oxaloacetate transaminase in ischemic stroke: an experimental study

Neuroprotective effect of neuroserpin in rat primary cortical cultures after oxygen and glucose deprivation and tPA.

Neuroprotective effects of dexmedetomidine conditioning strategies: Evidences from an in vitro model of cerebral ischemia

Neurorepair versus neuroprotection in stroke.

Obesity Paradox in Ischemic Stroke: Clinical and Molecular Insights

Oxaloacetate: a novel neuroprotective for acute ischemic stroke

Periodontal inflammation is related to increased serum calcitonin gene-related peptide levels in patients with chronic migraine