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Lista de obras de Alexander J. Lazar

A Comprehensive Pan-Cancer Molecular Study of Gynecologic and Breast Cancers

artículo científico publicado en 2018

A Preexisting Rare PIK3CAE545K Subpopulation Confers Clinical Resistance to MEK plus CDK4/6 Inhibition in NRAS Melanoma and Is Dependent on S6K1 Signaling.

artículo científico publicado en 2018

A Subgroup of Melanocytic Nevi on the Distal Lower Extremity (Ankle) Shares Features of Acral Nevi, Dysplastic Nevi, and Melanoma In Situ

artículo científico publicado en 2007

A Window Into Clinical Next-Generation Sequencing-Based Oncology Testing Practices.

artículo científico publicado en 2017

A keratinocyte hypermotility/growth-arrest response involving laminin 5 and p16INK4A activated in wound healing and senescence

artículo científico publicado en 2006

A multicenter phase 1 study of PX-866 in combination with docetaxel in patients with advanced solid tumours.

artículo científico publicado en 2013

A nonrandom association of gastrointestinal stromal tumor (GIST) and desmoid tumor (deep fibromatosis): case series of 28 patients

artículo científico publicado en 2011

A novel AKT3 mutation in melanoma tumours and cell lines

artículo científico publicado en 2008

A randomized, phase II study of preoperative plus postoperative imatinib in GIST: evidence of rapid radiographic response and temporal induction of tumor cell apoptosis

artículo científico publicado en 2008

AXL is a potential therapeutic target in dedifferentiated and pleomorphic liposarcomas

artículo científico publicado en 2015

Activated MET is a molecular prognosticator and potential therapeutic target for malignant peripheral nerve sheath tumors

artículo científico publicado en 2011

Activity of dasatinib against L576P KIT mutant melanoma: molecular, cellular, and clinical correlates

artículo científico publicado en 2009

Activity of temozolomide and bevacizumab in the treatment of locally advanced, recurrent, and metastatic hemangiopericytoma and malignant solitary fibrous tumor

artículo científico publicado en 2011

Adipophilin expression in sebaceous tumors and other cutaneous lesions with clear cell histology: an immunohistochemical study of 117 cases

artículo científico publicado en 2010

American Joint Committee on Cancer acceptance criteria for inclusion of risk models for individualized prognosis in the practice of precision medicine

artículo científico publicado en 2016

An Integrated TCGA Pan-Cancer Clinical Data Resource to Drive High-Quality Survival Outcome Analytics

artículo científico publicado en 2018

An erythematous plaque on the face

artículo científico publicado en 2006

An experimental model for the study of well-differentiated and dedifferentiated liposarcoma; deregulation of targetable tyrosine kinase receptors

artículo científico publicado en 2010

Analysis of Clinical and Molecular Factors Impacting Oncologic Outcomes in Undifferentiated Pleomorphic Sarcoma.

artículo científico publicado en 2016

Analysis of HSP27 and the Autophagy Marker LC3B+ Puncta Following Preoperative Chemotherapy Identifies High-Risk Osteosarcoma Patients

artículo científico publicado en 2018

Analysis of Immune Signatures in Longitudinal Tumor Samples Yields Insight into Biomarkers of Response and Mechanisms of Resistance to Immune Checkpoint Blockade

artículo científico publicado en 2016

Analysis of prognostic factors impacting oncologic outcomes after neoadjuvant tyrosine kinase inhibitor therapy for gastrointestinal stromal tumors

artículo científico publicado en 2014

Analysis of the immune infiltrate in undifferentiated pleomorphic sarcoma of the extremity and trunk in response to radiotherapy: Rationale for combination neoadjuvant immune checkpoint inhibition and radiotherapy

artículo científico publicado en 2017

Analysis of αv integrin protein expression in human eyelid and periorbital squamous cell carcinomas

artículo científico publicado en 2011

Androgen receptor blockade promotes response to BRAF/MEK-targeted therapy

artículo científico publicado en 2022

Angiogenesis-promoting gene patterns in alveolar soft part sarcoma

artículo científico publicado en 2007

Angiosarcoma: a tissue microarray study with diagnostic implications

artículo científico publicado en 2013

Angiosarcoma: clinical and molecular insights

artículo científico publicado en 2010

Antitumor effects of pharmacological EZH2 inhibition on malignant peripheral nerve sheath tumor through the miR-30a and KPNB1 pathway

artículo científico publicado en 2015

Appropriate Use Criteria in Dermatopathology: Initial Recommendations from the American Society of Dermatopathology

artículo científico publicado en 2018

Assessing inter-component heterogeneity of biphasic uterine carcinosarcomas

artículo científico publicado en 2018

Association of intratumoral vascular endothelial growth factor expression and clinical outcome for patients with gastrointestinal stromal tumors treated with imatinib mesylate

artículo científico publicado en 2007

Author Correction: Fecal microbiota transplantation for refractory immune checkpoint inhibitor-associated colitis

artículo científico publicado en 2019

Author Correction: Neoadjuvant immune checkpoint blockade in high-risk resectable melanoma

artículo científico publicado en 2018

Autophagic survival in resistance to histone deacetylase inhibitors: novel strategies to treat malignant peripheral nerve sheath tumors

artículo científico publicado en 2010

Autophagy inhibition and antimalarials promote cell death in gastrointestinal stromal tumor (GIST).

artículo científico publicado en 2010

B cells and tertiary lymphoid structures promote immunotherapy response

artículo científico publicado en 2020

B7-H3 Expression in Merkel Cell Carcinoma-Associated Endothelial Cells Correlates with Locally Aggressive Primary Tumor Features and Increased Vascular Density

scientific article published on 26 February 2019

BCOR-CCNB3 fusions are frequent in undifferentiated sarcomas of male children

artículo científico publicado en 2014

BRAF, NRAS and KIT sequencing analysis of spindle cell melanoma

artículo científico publicado en 2012

Basal cell carcinoma with matrical differentiation: a case study with analysis of beta-catenin

artículo científico publicado en 2005

Beyond BRAF(V600): clinical mutation panel testing by next-generation sequencing in advanced melanoma

artículo científico publicado en 2014

COL1A1:PDGFB chimeric transcripts are not present in indeterminate fibrohistiocytic lesions of the skin

artículo científico publicado en 2010

CTNNB1 45F mutation is a molecular prognosticator of increased postoperative primary desmoid tumor recurrence: an independent, multicenter validation study.

artículo científico publicado en 2013

CTNNB1 genotyping and APC screening in pediatric desmoid tumors: a proposed algorithm

artículo científico publicado en 2012

CXCR4/CXCL12 mediate autocrine cell- cycle progression in NF1-associated malignant peripheral nerve sheath tumors

artículo científico publicado en 2013

Can MDM2 analytical tests performed on core needle biopsy be relied upon to diagnose well-differentiated liposarcoma?

article

Cell-of-Origin Patterns Dominate the Molecular Classification of 10,000 Tumors from 33 Types of Cancer

artículo científico publicado en 2018

Cellular blue nevi of the eyelid: A possible diagnostic pitfall

artículo científico publicado en 2008

Challenges in next generation sequencing analysis of somatic mutations in transplant patients

artículo científico publicado en 2018

Characteristic Ber-EP4 and EMA expression in sebaceoma is immunohistochemically distinct from basal cell carcinoma

artículo científico publicado en 2007

Circulating Tumor DNA Analysis in Patients With Cancer: American Society of Clinical Oncology and College of American Pathologists Joint Review

artículo científico publicado en 2018

Circulating Tumor DNA Analysis in Patients With Cancer: American Society of Clinical Oncology and College of American Pathologists Joint Review.

artículo científico publicado en 2018

Clinical Observations and Molecular Variables of Primary Vascular Leiomyosarcoma

artículo científico publicado en 2015

Clinical characteristics and outcomes with specific BRAF and NRAS mutations in patients with metastatic melanoma

artículo científico publicado en 2013

Clinical outcomes of molecularly confirmed clear cell sarcoma from a single institution and in comparison with data from the Surveillance, Epidemiology, and End Results registry

artículo científico publicado en 2009

Clinical responses to selumetinib (AZD6244; ARRY-142886)-based combination therapy stratified by gene mutations in patients with metastatic melanoma

artículo científico publicado en 2012

Clinical responses to vemurafenib in patients with metastatic papillary thyroid cancer harboring BRAF(V600E) mutation

scientific article published on 17 July 2013

Clinical, Molecular, and Immune Analysis of Dabrafenib-Trametinib Combination Treatment for BRAF Inhibitor-Refractory Metastatic Melanoma: A Phase 2 Clinical Trial

artículo científico publicado en 2016

Clinical, Pathological, and Molecular Variables Predictive of Malignant Peripheral Nerve Sheath Tumor Outcome

article

Clinical, histopathologic, molecular and therapeutic findings in a large kindred with gastrointestinal stromal tumor

artículo científico

Clinicopathologic considerations: how can we fine tune our approach to sarcoma?

artículo científico

Clinicopathological analysis of ATRX, DAXX and NOTCH receptor expression in angiosarcomas.

artículo científico publicado en 2017

Clinicopathological features and clinical outcomes associated with TP53 and BRAFNon-V600 mutations in cutaneous melanoma patients

artículo científico publicado en 2016

Clinicopathological variables of sporadic schwannomas of peripheral nerve in 291 patients and expression of biologically relevant markers.

artículo científico publicado en 2017

Co-targeting PI3K, mTOR, and IGF1R with small molecule inhibitors for treating undifferentiated pleomorphic sarcoma.

artículo científico publicado en 2017

Combined vascular endothelial growth factor receptor/epidermal growth factor receptor blockade with chemotherapy for treatment of local, uterine, and metastatic soft tissue sarcoma

artículo científico publicado en 2008

Combining EGFR and mTOR blockade for the treatment of epithelioid sarcoma

artículo científico publicado en 2011

Comparative Molecular Analysis of Gastrointestinal Adenocarcinomas

artículo científico publicado en 2018

Comparative immunologic characterization of autoimmune giant cell myocarditis with ipilimumab

artículo científico publicado en 2017

Comparison of Laboratory-Developed Tests and FDA-Approved Assays for BRAF, EGFR, and KRAS Testing.

artículo científico publicado en 2017

Complete Soft Tissue Sarcoma Resection is a Viable Treatment Option for Select Elderly Patients

artículo científico publicado en 2009

Complete loss of PTEN protein expression correlates with shorter time to brain metastasis and survival in stage IIIB/C melanoma patients with BRAFV600 mutations

artículo científico publicado en 2014

Complete response of stage IV anal mucosal melanoma expressing KIT Val560Asp to the multikinase inhibitor sorafenib

artículo científico publicado en 2008

Comprehensive Analysis of Alternative Splicing Across Tumors from 8,705 Patients

artículo científico

Comprehensive Characterization of Cancer Driver Genes and Mutations

artículo científico publicado en 2018

Contemporary pathology of gastrointestinal stromal tumors

artículo científico publicado en 2009

Correlation between KIT expression and KIT mutation in melanoma: a study of 173 cases with emphasis on the acral-lentiginous/mucosal type

artículo científico publicado en 2009

Correlative Analyses of the SARC028 Trial Reveal an Association Between Sarcoma-Associated Immune Infiltrate and Response to Pembrolizumab

artículo científico publicado en 2020

Corrigendum

scientific article published on 05 January 2018

Cross species genomic analysis identifies a mouse model as undifferentiated pleomorphic sarcoma/malignant fibrous histiocytoma

artículo científico publicado en 2009

Cutaneous and subcutaneous metastases of gastrointestinal stromal tumors: a series of 5 cases with molecular analysis

artículo científico publicado en 2009

Cutaneous clear cell sarcoma: a clinicopathologic, immunohistochemical, and molecular analysis of 12 cases emphasizing its distinction from dermal melanoma

artículo científico publicado en 2010

Cutaneous digital papillary adenocarcinoma: a clinicopathologic study of 31 cases of a rare neoplasm with new observations

artículo científico publicado en 2012

Cutaneous nodular fasciitis with genetic analysis: a case series

artículo científico publicado en 2016

Dermatofibrosarcoma protuberans COL1A1-PDGFB fusion is identified in virtually all dermatofibrosarcoma protuberans cases when investigated by newly developed multiplex reverse transcription polymerase chain reaction and fluorescence in situ hybridiz

artículo científico publicado en 2007

Dermatofibrosarcoma protuberans and giant cell fibroblastoma exhibit CD99 positivity.

artículo científico publicado en 2008

Dermatofibrosarcoma protuberans with unusual sarcomatous transformation: a series of 4 cases with molecular confirmation

artículo científico publicado en 2011

Desmoid Tumor

article

Desmoid tumor: a disease opportune for molecular insights

artículo científico publicado en 2008

Desmoid tumor: from surgical extirpation to molecular dissection.

scientific article published on July 2009

Detection and characterization of EWSR1/ATF1 and EWSR1/CREB1 chimeric transcripts in clear cell sarcoma (melanoma of soft parts).

artículo científico publicado en 2009

Detection of MDM2 gene amplification or protein expression distinguishes sclerosing mesenteritis and retroperitoneal fibrosis from inflammatory well-differentiated liposarcoma

article

Detection of myxoid liposarcoma-associated FUS-DDIT3 rearrangement variants including a newly identified breakpoint using an optimized RT-PCR assay

artículo científico publicado en 2010

Diagnosis, management, and outcome of patients with dedifferentiated liposarcoma systemic metastasis

artículo científico publicado en 2011

Diagnostic Value of TLE1 in Synovial Sarcoma: A Systematic Review and Meta-Analysis

scientific article published on 29 January 2020

Differential expression of cysteine dioxygenase 1 in complex karyotype liposarcomas

artículo científico publicado en 2014

Distinctive Dermal Clear Cell Mesenchymal Neoplasm: Clinicopathologic Analysis of Five Cases

article

Driver Fusions and Their Implications in the Development and Treatment of Human Cancers

artículo científico publicado en 2018

Dual Roles of RNF2 in Melanoma Progression

artículo científico publicado en 2015

Dual targeting of AKT and mammalian target of rapamycin: a potential therapeutic approach for malignant peripheral nerve sheath tumor

artículo científico publicado en 2009

Dual targeting of mTOR and aurora-A kinase for the treatment of uterine Leiomyosarcoma

artículo científico publicado en 2012

ERG and FLI1 protein expression in epithelioid sarcoma

EWSR1 fusion proteins mediate PAX7 expression in Ewing sarcoma

artículo científico publicado en 2017

EZH2-miR-30d-KPNB1 pathway regulates malignant peripheral nerve sheath tumour cell survival and tumourigenesis

artículo científico publicado en 2014

Efficacy of first-line doxorubicin and ifosfamide in myxoid liposarcoma

artículo científico publicado en 2012

Epidermal growth factor receptor (EGFR) expression in periocular and extraocular sebaceous carcinoma

artículo científico publicado en 2009

Epidermal growth factor receptor blockade in combination with conventional chemotherapy inhibits soft tissue sarcoma cell growth in vitro and in vivo

artículo científico publicado en 2008

Epidermodysplasia verruciformis in the setting of graft-versus-host disease

Epithelioid inflammatory myofibroblastic sarcoma: An aggressive intra-abdominal variant of inflammatory myofibroblastic tumor with nuclear membrane or perinuclear ALK.

artículo científico publicado en 2011

Epithelioid sarcoma and unclassified sarcoma with epithelioid features: clinicopathological variables, molecular markers, and a new experimental model

artículo científico publicado en 2011

Establishment and characterization of a new human myxoid liposarcoma cell line (DL-221) with the FUS-DDIT3 translocation.

artículo científico publicado en 2016

Estrogen receptor alpha and androgen receptor are commonly expressed in well-differentiated liposarcoma

artículo científico publicado en 2014

Evaluation of response after neoadjuvant treatment in soft tissue sarcomas; the European Organization for Research and Treatment of Cancer-Soft Tissue and Bone Sarcoma Group (EORTC-STBSG) recommendations for pathological examination and reporting.

artículo científico publicado en 2015

Evaluation of response after pre-operative radiotherapy in soft tissue sarcomas; the European Organisation for Research and Treatment of Cancer-Soft Tissue and Bone Sarcoma Group (EORTC-STBSG) and Imaging Group recommendations for radiological exami

artículo científico publicado en 2016

Ewing's sarcoma: standard and experimental treatment options

scientific article published on April 2009

Examination of mutations in BRAF, NRAS, and PTEN in primary cutaneous melanoma

artículo científico publicado en 2006

Exploiting antitumor immunity to overcome relapse and improve remission duration

artículo científico publicado en 2011

Expression of 'drugable' tyrosine kinase receptors in malignant peripheral nerve sheath tumour: potential molecular therapeutic targets for a chemoresistant cancer

artículo científico publicado en 2011

Expression of ERG, an Ets family transcription factor, distinguishes cutaneous angiosarcoma from histological mimics

Expression of ERG, an Ets family transcription factor, identifies ERG-rearranged Ewing sarcoma.

artículo científico publicado en 2012

Extensive adipocytic maturation can be seen in myxoid liposarcomas treated with neoadjuvant doxorubicin and ifosfamide and pre-operative radiation therapy

artículo científico publicado en 2012

Extensive survey of STAT6 expression in a large series of mesenchymal tumors

artículo científico publicado en 2015

Extraskeletal Osteosarcomas: A Case Made for Combined Modality Local Therapy With Radiation and Surgery

scientific article published on 01 March 2019

FAP-related desmoid tumors: a series of 44 patients evaluated in a cancer referral center

artículo científico publicado en 2012

FUS rearrangements are rare in ‘pure’ sclerosing epithelioid fibrosarcoma

Fecal microbiota transplantation for refractory immune checkpoint inhibitor-associated colitis

scientific article published on 12 November 2018

Fluorescence in situ hybridization is a useful ancillary diagnostic tool for extraskeletal myxoid chondrosarcoma

Frequency and spectrum of BRAF mutations in a retrospective, single-institution study of 1112 cases of melanoma

artículo científico publicado en 2012

Galectin-3 Expression Is Associated with Tumor Progression and Pattern of Sun Exposure in Melanoma

scientific article published on 01 November 2006

Gankyrin is a predictive and oncogenic factor in well-differentiated and dedifferentiated liposarcoma.

artículo científico publicado en 2014

Gauging NOTCH1 Activation in Cancer Using Immunohistochemistry

artículo científico publicado en 2013

Gene Expression Analysis Identifies Novel Targets for Cervical Cancer Therapy

article

Genetic aberrations in soft tissue leiomyosarcoma

scientific article published on 22 July 2008

Genetic aberrations of gastrointestinal stromal tumors

artículo científico publicado en 2008

Genetic alterations in signaling pathways in melanoma

artículo científico publicado en 2006

Genomic Classification of Cutaneous Melanoma

artículo científico publicado en 2015

Genomic and Functional Approaches to Understanding Cancer Aneuploidy

artículo científico publicado en 2018

Genomic and immune heterogeneity are associated with differential responses to therapy in melanoma.

artículo científico publicado en 2017

Genomic profiling of dedifferentiated liposarcoma compared to matched well-differentiated liposarcoma reveals higher genomic complexity and a common origin.

artículo científico publicado en 2018

Genomic, Pathway Network, and Immunologic Features Distinguishing Squamous Carcinomas

artículo científico publicado en 2018

Genomics, morphoproteomics, and treatment patterns of alveolar soft part sarcoma patients and response to multiple experimental therapies

scientific article published on 03 March 2020

Gut microbiome modulates response to anti-PD-1 immunotherapy in melanoma patients.

artículo científico publicado en 2017

Heterogeneity and immunophenotypic plasticity of malignant cells in human liposarcomas

artículo científico publicado en 2013

High prevalence ofp53 exon 4 mutations in soft tissue sarcoma

artículo científico publicado en 2007

High-Throughput Screening of Myxoid Liposarcoma Cell Lines: Survivin Is Essential for Tumor Growth

artículo científico publicado en 2017

High-resolution genomic mapping reveals consistent amplification of the fibroblast growth factor receptor substrate 2 gene in well-differentiated and dedifferentiated liposarcoma

artículo científico publicado en 2011

Histologic variability in solitary fibrous tumors reflects angiogenic and growth factor signaling pathway alterations

artículo científico publicado en 2015

Histopathologic Evaluation of Atypical Neurofibromatous Tumors and Their Transformation into Malignant Peripheral Nerve Sheath Tumor in Neurofibromatosis 1 Patients - A Consensus Overview.

artículo científico publicado en 2017

Hotspot mutation panel testing reveals clonal evolution in a study of 265 paired primary and metastatic tumors

artículo científico publicado en 2015

How Do We Make Clinical Molecular Testing for Cancer Standard of Care for Pathology Departments?

artículo científico publicado en 2016

Human sebaceous tumors harbor inactivating mutations in LEF1.

artículo científico publicado en 2006

IFN regulatory factor 8 sensitizes soft tissue sarcoma cells to death receptor-initiated apoptosis via repression of FLICE-like protein expression

artículo científico publicado en 2009

IGF-1R and mTOR Blockade: Novel Resistance Mechanisms and Synergistic Drug Combinations for Ewing Sarcoma

artículo científico publicado en 2016

INK4a/ARF [corrected] inactivation with activation of the NF-κB/IL-6 pathway is sufficient to drive the development and growth of angiosarcoma

artículo científico publicado en 2012

Identification of a disease-defining gene fusion in epithelioid hemangioendothelioma

artículo científico publicado en 2011

Identification of preoperative factors associated with outcomes following surgical management of intra-abdominal recurrent or metastatic GIST following neoadjuvant tyrosine kinase inhibitor therapy

artículo científico publicado en 2018

Imatinib mesylate in advanced dermatofibrosarcoma protuberans: pooled analysis of two phase II clinical trials

artículo científico publicado en 2010

Immuno-genomic landscape of osteosarcoma

scientific article published on 21 February 2020

Impact of sentinel lymphadenectomy on survival in a murine model of melanoma

article

Impact of surgical resection for subdiaphragmatic paragangliomas

artículo científico publicado en 2014

Increased H3K9me3 drives dedifferentiated phenotype via KLF6 repression in liposarcoma

artículo científico publicado en 2015

Increased midkine expression correlates with desmoid tumour recurrence: a potential biomarker and therapeutic target

artículo científico publicado en 2011

Increased vascular endothelial growth factor-C expression is insufficient to induce lymphatic metastasis in human soft-tissue sarcomas

artículo científico publicado en 2009

Index report of cutaneous angiosarcomas with strong positivity for tyrosinase mimicking melanoma with further evaluation of melanocytic markers in a large angiosarcoma series

artículo científico publicado en 2017

Insights into developmental mechanisms and cancers in the mammalian intestine derived from serial analysis of gene expression and study of the hepatoma-derived growth factor (HDGF).

artículo científico publicado en 2004

Integrated Molecular and Clinical Analysis of AKT Activation in Metastatic Melanoma

artículo científico publicado en 2009

Integrated molecular analysis of tumor biopsies on sequential CTLA-4 and PD-1 blockade reveals markers of response and resistance.

artículo científico publicado en 2017

Integrated proteomics and genomics analysis reveals a novel mesenchymal to epithelial reverting transition in leiomyosarcoma through regulation of slug

artículo científico publicado en 2010

Integrative Analysis Identifies Four Molecular and Clinical Subsets in Uveal Melanoma

artículo científico publicado en 2017

Integrative Analysis Identifies Four Molecular and Clinical Subsets in Uveal Melanoma

artículo científico publicado en 2018

Integrative genomic characterization and a genomic staging system for gastrointestinal stromal tumors

artículo científico publicado en 2010

Introducing new College of American Pathologists reporting templates for cancer biomarkers

artículo científico publicado en 2013

Involvement of the PI3K/Akt pathway in myxoid/round cell liposarcoma

artículo científico publicado en 2011

Kinetochore size variation in mammalian chromosomes: an image analysis study with evolutionary implications

artículo científico publicado en 1989

Liposarcoma in children and young adults: a multi-institutional experience

artículo científico publicado en 2011

Localized and metastatic myxoid/round cell liposarcoma: clinical and molecular observations

artículo científico publicado en 2013

Locoregional disease patterns in well-differentiated and dedifferentiated retroperitoneal liposarcoma: implications for the extent of resection?

artículo científico publicado en 2014

Long-Term Outcomes for Patients With Desmoid Fibromatosis Treated With Radiation Therapy: A 10-Year Update and Re-evaluation of the Role of Radiation Therapy for Younger Patients

artículo científico publicado en 2018

Long-term outcomes in patients with radiation-associated angiosarcomas of the breast following surgery and radiotherapy for breast cancer

artículo científico publicado en 2012

Loss of H3K27 tri-methylation is a diagnostic marker for malignant peripheral nerve sheath tumors and an indicator for an inferior survival

artículo científico publicado en 2016

Loss of H3K27 tri-methylation is a diagnostic marker for malignant peripheral nerve sheath tumors and an indicator for an inferior survival.

artículo científico publicado en 2016

Loss of PTEN Promotes Resistance to T Cell-Mediated Immunotherapy.

artículo científico publicado en 2015

Lymphocyte Composition and Distribution in Inflammatory, Well-differentiated Retroperitoneal Liposarcoma

article

MAGE-A3 is a Clinically Relevant Target in Undifferentiated Pleomorphic Sarcoma/Myxofibrosarcoma

artículo científico publicado en 2019

MRI may be used as a prognostic indicator in patients with extra-abdominal desmoid tumours

artículo científico publicado en 2015

MUC4 Is a Sensitive and Extremely Useful Marker for Sclerosing Epithelioid Fibrosarcoma

artículo científico publicado en 2012

Machine Learning Identifies Stemness Features Associated with Oncogenic Dedifferentiation

artículo científico publicado en 2018

Malignant peripheral nerve sheath tumour (MPNST): the clinical implications of cellular signalling pathways

scientific article published on 19 October 2009

Mechanisms of resistance to imatinib and sunitinib in gastrointestinal stromal tumor.

artículo científico publicado en 2010

Melanoma staging: Evidence-based changes in the American Joint Committee on Cancer eighth edition cancer staging manual

artículo científico publicado en 2017

Merkel Cell Tumor in a Trichilemmal Cyst: Collision or Association?

article published in 2007

Mesenchymal Chondrosarcoma: a Review with Emphasis on its Fusion-Driven Biology

artículo científico publicado en 2018

Mesenchymal to epithelial transition in sarcomas

artículo científico publicado en 2013

Metastasizing adenocarcinoma and multiple neoplastic proliferations arising in a nevus sebaceus

artículo científico publicado en 2007

Metastatic atypical fibroxanthoma: a series of 11 cases including with minimal and no subcutaneous involvement

artículo científico publicado en 2015

Metastatic basal cell carcinoma exhibits reduced actin expression

artículo científico publicado en 2008

Metastatic hidradenocarcinoma with demonstration of Her-2/neu gene amplification by fluorescence in situ hybridization: potential treatment implications

article

MiR-155 is a liposarcoma oncogene that targets casein kinase-1α and enhances β-catenin signaling

artículo científico publicado en 2012

Mice null for the deubiquitinase USP18 spontaneously develop leiomyosarcomas

artículo científico publicado en 2015

Midkine enhances soft-tissue sarcoma growth: a possible novel therapeutic target

artículo científico publicado en 2008

Modeling Ewing sarcoma tumors in vitro with 3D scaffolds

artículo científico publicado en 2013

Modeling synovial sarcoma metastasis in the mouse: PI3'-lipid signaling and inflammation

artículo científico publicado en 2016

Molecular Profiling Reveals Unique Immune and Metabolic Features of Melanoma Brain Metastases

artículo científico publicado en 2019

Molecular and immunological associations of elevated serum lactate dehydrogenase in metastatic melanoma patients: A fresh look at an old biomarker

artículo científico publicado en 2020

Molecular approaches to resolve diagnostic dilemmas: the case of gastrointestinal stromal tumor and leiomyosarcoma

artículo científico publicado en 2007

Molecular characterization of epithelioid haemangioendotheliomas identifies novel WWTR1-CAMTA1 fusion variants

scientific article published on 14 May 2015

Molecular diagnosis of sarcomas: chromosomal translocations in sarcomas

artículo científico publicado en 2006

Molecular profiling of patient-matched brain and extracranial melanoma metastases implicates the PI3K pathway as a therapeutic target

artículo científico publicado en 2014

Molecular profiling of sarcomas: new vistas for precision medicine.

artículo científico publicado en 2017

Molecular prognosticators of complex karyotype soft tissue sarcoma outcome: a tissue microarray-based study

artículo científico publicado en 2009

Muir-Torre syndrome appropriate use criteria: Effect of patient age on appropriate use scores

scientific article published on 26 April 2019

Multi-site desmoplastic small round cell tumors are genetically related and immune-cold

artículo científico publicado en 2022

Multigene clinical mutational profiling of breast carcinoma using next-generation sequencing

artículo científico publicado en 2015

Multimodality Treatment of Desmoplastic Small Round Cell Tumor: Chemotherapy and Complete Cytoreductive Surgery Improve Patient Survival

artículo científico publicado en 2018

Myxofibrosarcoma.

artículo científico publicado en 2016

NF1+/- Hematopoietic Cells Accelerate Malignant Peripheral Nerve Sheath Tumor Development without Altering Chemotherapy Response.

artículo científico publicado en 2017

NKD2, a negative regulator of Wnt signaling, suppresses tumor growth and metastasis in osteosarcoma

artículo científico publicado en 2015

NRAS mutation status is an independent prognostic factor in metastatic melanoma

artículo científico publicado en 2012

NY-ESO-1 (CTAG1B) expression in mesenchymal tumors

artículo científico publicado en 2014

Neoadjuvant immune checkpoint blockade in high-risk resectable melanoma

artículo científico publicado en 2018

Neoadjuvant plus adjuvant dabrafenib and trametinib versus standard of care in patients with high-risk, surgically resectable melanoma: a single-centre, open-label, randomised, phase 2 trial

artículo científico publicado en 2018

Neoadjuvant treatment of soft-tissue sarcoma: a multimodality approach

artículo científico publicado en 2010

Nephrogenic fibrosing dermopathy with recurrence after allograft failure

article published in 2007

Nevoid melanoma

artículo científico publicado en 2011

New frontiers in the treatment of liposarcoma, a therapeutically resistant malignant cohort

scientific article published on 18 December 2010

New perspectives for staging and prognosis in soft tissue sarcoma

artículo científico publicado en 2008

New strategies in melanoma: molecular testing in advanced disease

artículo científico publicado en 2012

New therapeutic targets in soft tissue sarcoma

artículo científico publicado en 2012

New, tolerable γ-secretase inhibitor takes desmoid down a notch

artículo científico publicado en 2014

Non-Radiographic Risk Factors Differentiating Atypical Lipomatous Tumors from Lipomas

artículo científico publicado en 2016

Noncontact measurement of elasticity for the detection of soft-tissue tumors using phase-sensitive optical coherence tomography combined with a focused air-puff system

artículo científico publicado en 2012

Novel algorithmic approach predicts tumor mutation load and correlates with immunotherapy clinical outcomes using a defined gene mutation set.

artículo científico publicado en 2016

Novel systemic therapies in advanced liposarcoma: a review of recent clinical trial results

artículo científico publicado en 2013

Nuclear PTEN tumor-suppressor functions through maintaining heterochromatin structure

artículo científico publicado en 2015

Nuclear β-catenin localization and mutation of the CTNNB1 gene: a context-dependent association.

artículo científico publicado en 2018

Oncogenic Signaling Pathways in The Cancer Genome Atlas

artículo científico publicado en 2018

Optimizing Treatment of Desmoid Tumors

article

Oral-Cutaneous CD4-Positive T-cell Lymphoma: A Study of Two Patients

artículo científico publicado en 2007

Outcome of Locally Recurrent and Metastatic Angiosarcoma

artículo científico publicado en 2009

Overexpressed PRAME is a potential immunotherapy target in sarcoma subtypes

artículo científico publicado en 2017

PAX3/7-FOXO1 fusion status in older rhabdomyosarcoma patient population by fluorescent in situ hybridization

artículo científico publicado en 2011

PAX7 Expression in Rhabdomyosarcoma, Related Soft Tissue Tumors, and Small Round Blue Cell Neoplasms

artículo científico publicado en 2016

PAX7 expression in sarcomas bearing the EWSR1-NFATC2 translocation

artículo científico publicado en 2018

PRKCI promotes immune suppression in ovarian cancer

artículo científico publicado en 2017

Pan-cancer insights from The Cancer Genome Atlas: the pathologist's perspective

artículo científico publicado en 2017

Papulo-vesicular eruption

artículo científico publicado en 2007

Parallel profiling of immune infiltrate subsets in uveal melanoma versus cutaneous melanoma unveils similarities and differences: A pilot study.

artículo científico publicado en 2017

Pathogenic Germline Variants in 10,389 Adult Cancers

artículo científico publicado en 2018

Pathology of gastrointestinal stromal tumors

artículo científico publicado en 2012

Patterns of recurrence and survival in sporadic, neurofibromatosis Type 1-associated, and radiation-associated malignant peripheral nerve sheath tumors

artículo científico publicado en 2016

Pembrolizumab in advanced soft-tissue sarcoma and bone sarcoma (SARC028): a multicentre, two-cohort, single-arm, open-label, phase 2 trial

artículo científico publicado en 2017

Perspective on Oncogenic Processes at the End of the Beginning of Cancer Genomics

artículo científico publicado en 2018

Phase 1 adaptive dose-finding study of neoadjuvant gemcitabine combined with radiation therapy for patients with high-risk extremity and trunk soft tissue sarcoma

artículo científico publicado en 2015

Phase I study of the combination of sorafenib and temsirolimus in patients with metastatic melanoma

artículo científico publicado en 2012

Phase II study of neoadjuvant checkpoint blockade in patients with surgically resectable undifferentiated pleomorphic sarcoma and dedifferentiated liposarcoma

artículo científico publicado en 2018

Phospholipase D activity is required for suppression of yeast phosphatidylinositol transfer protein defects

artículo científico publicado en 1998

Pilomatrix carcinomas contain mutations in CTNNB1, the gene encoding beta-catenin

artículo científico publicado en 2005

Pitfalls in assessing stromal tumor infiltrating lymphocytes (sTILs) in breast cancer

artículo científico publicado en 2020

Pleomorphic fibroma and dermal atypical lipomatous tumor: are they related?

artículo científico publicado en 2013

Pleomorphic liposarcoma: clinical observations and molecular variables

artículo científico publicado en 2011

Poly (ADP) ribose polymerase inhibition: A potential treatment of malignant peripheral nerve sheath tumor.

artículo científico publicado en 2015

Positive Tumor Response to Combined Checkpoint Inhibitors in a Patient With Refractory Alveolar Soft Part Sarcoma: A Case Report ⬇️

scientific article published on 06 July 2017

Primary Cutaneous Apocrine Carcinoma

Primary Synovial Sarcoma (SS) of the digestive system: a molecular and clinicopathological study of fifteen cases

artículo científico publicado en 2015

Primary chondro-osseous melanoma (chondrosarcomatous and osteosarcomatous melanoma).

artículo científico publicado en 2017

Primary cutaneous adenoid cystic carcinoma: a clinicopathologic and immunohistochemical study of 27 cases.

artículo científico publicado en 2013

Primary intracranial soft tissue sarcomas in children, adolescents, and young adults: single institution experience and review of the literature

artículo científico publicado en 2015

Primary vascular tumors and tumor-like lesions of the kidney: a clinicopathologic analysis of 25 cases.

artículo científico publicado en 2010

Primitive Nonneural Granular Cell Tumors of Skin

artículo científico publicado en 2005

Prognosis of T1 synovial sarcoma depends upon surgery by oncologic surgeons.

artículo científico publicado en 2016

Prognostic model for patient survival in primary anorectal mucosal melanoma: stage at presentation determines relevance of histopathologic features

artículo científico publicado en 2019

Progressive loss of myogenic differentiation in leiomyosarcoma has prognostic value

artículo científico publicado en 2015

Protocol for the examination of specimens from patients with gastrointestinal stromal tumor

artículo científico publicado en 2010

Protocol for the examination of specimens from patients with tumors of soft tissue

artículo científico publicado en 2010

Pseudocystic dermatofibrosarcoma protuberans: report of two cases and demonstration of COL1A1-PDGFB rearrangement

artículo científico publicado en 2012

Publisher Correction: Neoadjuvant immune checkpoint blockade in high-risk resectable melanoma

artículo científico publicado en 2018

R132C IDH1 Mutations Are Found in Spindle Cell Hemangiomas and Not in Other Vascular Tumors or Malformations

RNA interference of PARG could inhibit the metastatic potency of colon carcinoma cells via PI3-kinase/Akt pathway

artículo científico publicado en 2012

ROR2 is a novel prognostic biomarker and a potential therapeutic target in leiomyosarcoma and gastrointestinal stromal tumour

scientific article published on 17 February 2012

Rad51 overexpression contributes to chemoresistance in human soft tissue sarcoma cells: a role for p53/activator protein 2 transcriptional regulation

artículo científico publicado en 2007

Radiation-Associated Undifferentiated Pleomorphic Sarcoma is Associated with Worse Clinical Outcomes than Sporadic Lesions

artículo científico publicado en 2015

Radiation-induced Sarcomas Occurring in Desmoid-type Fibromatosis Are Not Always Derived From the Primary Tumor

artículo científico publicado en 2015

Recurrent PTPRB and PLCG1 mutations in angiosarcoma

artículo científico publicado en 2014

Renal cell carcinoma marker (RCC-Ma) is specific for cutaneous metastasis of renal cell carcinoma

artículo científico publicado en 2007

Report on computational assessment of Tumor Infiltrating Lymphocytes from the International Immuno-Oncology Biomarker Working Group

artículo científico publicado en 2020

Retracted: Vimentin Is a Novel Anti-Cancer Therapeutic Target; Insights from In Vitro and In Vivo Mice Xenograft Studies

artículo científico publicado en 2010

Retroperitoneal undifferentiated pleomorphic sarcoma having microsatellite instability associated with Muir-Torre syndrome: case report and review of literature

artículo científico publicado en 2013

Revealing retroperitoneal liposarcoma morphology using optical coherence tomography

Risk assessment in solitary fibrous tumors: validation and refinement of a risk stratification model.

artículo científico

Role of Elevated PHIP Copy Number as a Prognostic and Progression Marker for Cutaneous Melanoma

artículo científico publicado en 2018

Role of chemotherapy in dedifferentiated liposarcoma of the retroperitoneum: defining the benefit and challenges of the standard

artículo científico publicado en 2017

SAR405838: A Novel and Potent Inhibitor of the MDM2:p53 Axis for the Treatment of Dedifferentiated Liposarcoma.

artículo científico publicado en 2015

Sarcoma Brain Metastases: 28 Years of Experience at a Single Institution

artículo científico publicado en 2016

Sarcoma epidemiology and etiology: potential environmental and genetic factors

artículo científico publicado en 2008

Sarcoma metastases to the skin: a clinicopathologic study of 65 patients

artículo científico publicado en 2011

Sarcoma molecular testing: diagnosis and prognosis.

artículo científico publicado en 2007

Sebaceous neoplasia and Torre-Muir syndrome.

artículo científico publicado en 2007

Sebaceous neoplasia and the Muir-Torre syndrome: important connections with clinical implications.

artículo científico publicado en 2010

Sebaceous tumours contain a subpopulation of cells expressing the keratin 15 stem cell marker

artículo científico publicado en 2007

Short-term treatment with multi-drug regimens combining BRAF/MEK-targeted therapy and immunotherapy results in durable responses in <i>Braf</i>-mutated melanoma

artículo científico publicado en 2021

Single-cell dissection of intratumoral heterogeneity and lineage diversity in metastatic gastric adenocarcinoma

artículo científico publicado en 2021

Site and Tumor Type Predicts DNA Mismatch Repair Status in Cutaneous Sebaceous Neoplasia

artículo científico publicado en 2008

Solitary fibrous tumor: a clinicopathological study of 110 cases and proposed risk assessment model

artículo científico publicado en 2012

Somatic Copy Number Alterations at Oncogenic Loci Show Diverse Correlations with Gene Expression

artículo científico publicado en 2016

Spatial Organization and Molecular Correlation of Tumor-Infiltrating Lymphocytes Using Deep Learning on Pathology Images

artículo científico publicado en 2018

Spatially resolved analyses link genomic and immune diversity and reveal unfavorable neutrophil activation in melanoma

artículo científico publicado en 2020

Specific mutations in the beta-catenin gene (CTNNB1) correlate with local recurrence in sporadic desmoid tumors.

artículo científico publicado en 2008

Staging soft tissue sarcoma: evolution and change.

artículo científico publicado en 2006

Survivin is a viable target for the treatment of malignant peripheral nerve sheath tumors

artículo científico publicado en 2012

Synovial Sarcoma of the Head and Neck: A Single Institution Review.

artículo científico publicado en 2017

Synovial Sarcoma: Advances in Diagnosis and Treatment Identification of New Biologic Targets to Improve Multimodal Therapy.

artículo científico publicado en 2017

T-cell trafficking plays an essential role in tumor immunity

article

T-cell-rich angiomatoid polypoid pseudolymphoma of the skin: a clinicopathologic study of 17 cases and a proposed nomenclature

artículo científico publicado en 2011

TERT promoter mutations in solitary fibrous tumour

artículo científico publicado en 2018

TRAIL and doxorubicin combination induces proapoptotic and antiangiogenic effects in soft tissue sarcoma in vivo

artículo científico publicado en 2010

Targeted next generation sequencing of well-differentiated/dedifferentiated liposarcoma reveals novel gene amplifications and mutations.

artículo científico publicado en 2018

Targeted therapies for sarcomas: new roles for the pathologist

artículo científico

Targeting group I p21-activated kinases to control malignant peripheral nerve sheath tumor growth and metastasis.

artículo científico publicado en 2017

Targeting the Notch pathway: A potential therapeutic approach for desmoid tumors

artículo científico publicado en 2015

Targeting the PI3K/mTOR axis, alone and in combination with autophagy blockade, for the treatment of malignant peripheral nerve sheath tumors

artículo científico publicado en 2012

Telomerase suppresses formation of ALT-associated single-stranded telomeric C-circles

artículo científico publicado en 2013

Telomere dysfunction suppresses spontaneous tumorigenesis in vivo by initiating p53-dependent cellular senescence

artículo científico publicado en 2007

Template for Reporting Results of Biomarker Testing of Specimens From Patients With Gastrointestinal Stromal Tumors

artículo científico publicado en 2015

Template for Reporting Results of Biomarker Testing of Specimens From Patients With Melanoma

artículo científico publicado en 2015

The Cancer Genome Atlas Comprehensive Molecular Characterization of Renal Cell Carcinoma

article

The Cancer Genomics Resource List 2014.

artículo científico publicado en 2014

The Immune Landscape of Cancer

artículo científico publicado en 2018

The Importance of Lymphovascular Invasion in Uterine Adenosarcomas: Analysis of Clinical, Prognostic, and Treatment Outcomes

artículo científico publicado en 2018

The LPP1 and DPP1 gene products account for most of the isoprenoid phosphate phosphatase activities in Saccharomyces cerevisiae

artículo científico publicado en 1999

The SS18-SSX Fusion Oncoprotein Hijacks BAF Complex Targeting and Function to Drive Synovial Sarcoma

artículo científico publicado en 2018

The Skin Allograft Revisited: A Potentially Permanent Wound Coverage Option in the Critically Ill Patient

artículo científico publicado en 2009

The androgen receptor is a therapeutic target in desmoplastic small round cell sarcoma

artículo científico publicado en 2022

The clinical behavior of well differentiated liposarcoma can be extremely variable: A retrospective cohort study at a major sarcoma center

artículo científico publicado en 2018

The expression of c-Met pathway components in unclassified pleomorphic sarcoma/malignant fibrous histiocytoma (UPS/MFH): a tissue microarray study

artículo científico publicado en 2011

The genomic landscape of epithelioid sarcoma cell lines and tumours

artículo científico publicado en 2015

The hepatocyte growth factor receptor as a potential therapeutic target for dedifferentiated liposarcoma

artículo científico publicado en 2015

The long non-coding RNA NEAT1 promotes sarcoma metastasis by regulating RNA splicing pathways

scientific article published on 19 June 2020

The molecular pathology of sarcomas

artículo científico publicado en 2010

The path to a better biomarker: Application of a risk management framework for the implementation of PD-L1 and TILs as immuno-oncology biomarkers in breast cancer clinical trials and daily practice

scientific article published on 04 March 2020

The role of chemotherapy in advanced solitary fibrous tumors: a retrospective analysis

artículo científico publicado en 2013

The role of phosphorylated signal transducer and activator of transcription 3 (pSTAT3) in peripheral nerve sheath tumours.

artículo científico publicado en 2016

The usefulness of p63 detection for differentiating primary from metastatic skin adenocarcinomas

scientific article published on 01 September 2008

Three-dimensional computational analysis of optical coherence tomography images for the detection of soft tissue sarcomas

article

Trends in hepatocyte growth factor, insulin-like growth factor 1, thyroid-stimulating hormone, and leptin expression levels in uveal melanoma patient serum and tumor tissues: correlation to disease progression

artículo científico publicado en 2017

Trichilemmomas show loss of PTEN in Cowden syndrome but only rarely in sporadic tumors

article published in 2012

Tyrosine Kinase Inhibitor and Immune Checkpoint Inhibitor Responses in KIT-Mutant Metastatic Melanoma

artículo científico publicado en 2018

USP6 activation in nodular fasciitis by promoter-swapping gene fusions.

artículo científico publicado en 2017

Undifferentiated "round" cell ("Ewing-like") sarcoma: not always so-round nor Ewing-like

artículo científico publicado en 2017

Unlucky number 13? Differential effects of KIT exon 13 mutation in gastrointestinal stromal tumors

artículo científico publicado en 2008

Unphosphorylated STAT1 promotes sarcoma development through repressing expression of Fas and bad and conferring apoptotic resistance

artículo científico publicado en 2012

Use of clinical next-generation sequencing to identify melanomas harboring SMARCB1 mutations

artículo científico publicado en 2015

Use of p63 expression in distinguishing primary and metastatic cutaneous adnexal neoplasms from metastatic adenocarcinoma to skin

artículo científico publicado en 2007

Uterine leiomyosarcoma management, outcome, and associated molecular biomarkers: a single institution's experience

scientific article published on 20 January 2013

Uterine tumors with neuroectodermal differentiation: a series of 17 cases and review of the literature

artículo científico publicado en 2008

Utility of BRAF V600E Immunohistochemistry Expression Pattern as a Surrogate of BRAF Mutation Status in 154 Patients with Advanced Melanoma

artículo científico publicado en 2015

Validation of potential therapeutic targets in alveolar soft part sarcoma: an immunohistochemical study utilizing tissue microarray

Vimentin is a novel AKT1 target mediating motility and invasion

artículo científico publicado en 2011

Vincristine, Ifosfamide, and Doxorubicin for Initial Treatment of Ewing Sarcoma in Adults.

artículo científico

Wild-type p53 inhibits nuclear factor-kappaB-induced matrix metalloproteinase-9 promoter activation: implications for soft tissue sarcoma growth and metastasis

artículo científico publicado en 2006

Wt1 ablation and Igf2 upregulation in mice result in Wilms tumors with elevated ERK1/2 phosphorylation

artículo científico publicado en 2010

p53 Is a Master Regulator of Proteostasis in SMARCB1-Deficient Malignant Rhabdoid Tumors

scientific article published on 01 February 2019

p53 staining correlates with tumor type and location in sebaceous neoplasms

artículo científico publicado en 2012

‘Difficult to diagnose’ desmoid tumours: a potential role forCTNNB1mutational analysis

article

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