Lista de obras - Holger Wille - Dominio Público Uruguay

A Neuronal Culture System to Detect Prion Synaptotoxicity

artículo científico publicado en 2016

A novel Gerstmann-Sträussler-Scheinker disease mutation defines a precursor for amyloidogenic 8 kDa PrP fragments and reveals N-terminal structural changes shared by other GSS alleles.

artículo científico publicado en 2018

A synthetic peptide initiates Gerstmann-Sträussler-Scheinker (GSS) disease in transgenic mice

artículo científico publicado en 2000

Alzheimer-like paired helical filaments and antiparallel dimers formed from microtubule-associated protein tau in vitro ⬇️

artículo científico publicado el 1 de agosto de 1992

An easy method for bacterial expression and purification of wild-type and mutant superoxide dismutase 1 (SOD1).

artículo científico publicado en 2017

Assembly of natural and recombinant prion protein into fibrils

artículo científico publicado en 2005

Bioluminescence Imaging of Neuroinflammation in Transgenic Mice After Peripheral Inoculation of Alpha-Synuclein Fibrils

artículo científico publicado en 2017

Colloid formation by drugs in simulated intestinal fluid

artículo científico publicado en 2010

Combining molecular dynamics simulations and experimental analyses in protein misfolding

scientific article published on 01 January 2019

Comparing the Folds of Prions and Other Pathogenic Amyloids

artículo científico publicado en 2018

Conformational diversity of wild-type Tau fibrils specified by templated conformation change

artículo científico publicado en 2008

Deer Prion Proteins Modulate the Emergence and Adaptation of Chronic Wasting Disease Strains.

artículo científico publicado en 2015

Degradation of Fungal Prion HET-s(218-289) Induces Formation of a Generic Amyloid Fold ⬇️

artículo científico publicado el 15 de mayo de 2012

Destabilizing polymorphism in cervid prion protein hydrophobic core determines prion conformation and conversion efficiency

artículo científico publicado en 2017

Diverse, evolving conformer populations drive distinct phenotypes in frontotemporal lobar degeneration caused by the same MAPT-P301L mutation

artículo científico publicado en 2020

Eight prion strains have PrPSc molecules with different conformations ⬇️

artículo científico publicado el 1 de octubre de 1998

Engineering a 2D protein-DNA crystal

artículo científico publicado en 2005

Evolutionary descent of prion genes from the ZIP family of metal ion transporters

artículo científico publicado en 2009

Family reunion--the ZIP/prion gene family

artículo científico publicado en 2010

Full atomistic model of prion structure and conversion

scientific article published on 11 July 2019

Genes contributing to prion pathogenesis

artículo científico publicado en 2008

Homogeneous nanodiscs of native membranes formed by stilbene-maleic-acid copolymers

artículo científico publicado en 2020

In vitro conversion and seeded fibrillization of posttranslationally modified prion protein

artículo científico publicado en 2011

Influence of water, fat, and glycerol on the mechanism of thermal prion inactivation

scientific article published on 18 September 2007

Microtubule-associated protein tau, paired helical filaments, and phosphorylation.

artículo científico publicado en 1993

Molecular properties of complexes formed between the prion protein and synthetic peptides ⬇️

artículo científico publicado el 25 de julio de 1997

Native nanodiscs formed by styrene-maleic acid copolymer derivatives help recover infectious prion multimers bound to brain-derived lipids

artículo científico publicado en 2020

Neuroinvasion of α-Synuclein Prionoids after Intraperitoneal and Intraglossal Inoculation.

artículo científico publicado en 2016

Prion protein with a mutant N-terminal octarepeat region undergoes cobalamin-dependent assembly into high-molecular weight complexes

scientific article published on 07 March 2022

Prion uptake in the gut: identification of the first uptake and replication sites

scientific article (publication date: December 2011)

Protease-Resistant Prions Selectively Decrease Shadoo Protein ⬇️

artículo científico publicado el 17 de noviembre de 2011

Scrapie infectivity is independent of amyloid staining properties of the N-terminally truncated prion protein

artículo científico publicado en 2000

Secretory pathway retention of mutant prion protein induces p38-MAPK activation and lethal disease in mice

artículo científico publicado en 2016

Self-assembling small molecules form nanofibrils that bind procaspase-3 to promote activation

artículo científico publicado en 2011

Self-assembly of recombinant prion protein of 106 residues

artículo científico publicado en 2000

Separation of scrapie prion infectivity from PrP amyloid polymers

artículo científico publicado en 1996

Significance of native PLGA nanoparticles in the treatment of Alzheimer's disease pathology

artículo científico publicado en 2022

Small-molecule aggregates inhibit amyloid polymerization

artículo científico publicado en 2008

Solid-state NMR studies of the secondary structure of a mutant prion protein fragment of 55 residues that induces neurodegeneration

artículo científico publicado en 2001

Somatostatin binds to the human amyloid β peptide and favors the formation of distinct oligomers

artículo científico publicado en 2017

Structural studies of truncated forms of the prion protein PrP.

artículo científico publicado en 2015

Subcellular distribution of the prion protein in sickness and in health

artículo científico publicado en 2015

The CNS in inbred transgenic models of 4-repeat Tauopathy develops consistent tau seeding capacity yet focal and diverse patterns of protein deposition

artículo científico publicado en 2017

The Detection of Infectious Prions: In Vitro Conversion Assays Change the (Folding) Landscape

artículo científico publicado en 2016

The Structural Architecture of an Infectious Mammalian Prion Using Electron Cryomicroscopy

artículo científico publicado en 2016

The Structure of Mammalian Prions and Their Aggregates

artículo científico publicado en 2016

The Structure of PrPSc Prions

artículo científico publicado en 2018

The Structure of the Infectious Prion Protein and Its Propagation

artículo científico

The ZIP5 ectodomain co-localizes with PrP and may acquire a PrP-like fold that assembles into a dimer

artículo científico publicado en 2013

The chicken neural extracellular matrix molecule restrictin: similarity with EGF-, fibronectin type III-, and fibrinogen-like motifs

artículo científico publicado en 1992

The human brain somatostatin interactome: SST binds selectively to P-type family ATPases

artículo científico publicado en 2019

The structure of human prions: from biology to structural models-considerations and pitfalls

artículo científico publicado en 2014

The structure of the infectious prion protein: experimental data and molecular models

artículo científico publicado en 2014

Toll-like receptor-mediated immune response inhibits prion propagation.

artículo científico publicado en 2016

α-Synuclein strains target distinct brain regions and cell types

scientific article published on 02 December 2019

Lista de obras de Holger Wille

A Neuronal Culture System to Detect Prion Synaptotoxicity

A novel Gerstmann-Sträussler-Scheinker disease mutation defines a precursor for amyloidogenic 8 kDa PrP fragments and reveals N-terminal structural changes shared by other GSS alleles.

A synthetic peptide initiates Gerstmann-Sträussler-Scheinker (GSS) disease in transgenic mice

Alzheimer-like paired helical filaments and antiparallel dimers formed from microtubule-associated protein tau in vitro ⬇️

An easy method for bacterial expression and purification of wild-type and mutant superoxide dismutase 1 (SOD1).

Assembly of natural and recombinant prion protein into fibrils

Bioluminescence Imaging of Neuroinflammation in Transgenic Mice After Peripheral Inoculation of Alpha-Synuclein Fibrils

Colloid formation by drugs in simulated intestinal fluid

Combining molecular dynamics simulations and experimental analyses in protein misfolding

Comparing the Folds of Prions and Other Pathogenic Amyloids

Conformational diversity of wild-type Tau fibrils specified by templated conformation change

Deer Prion Proteins Modulate the Emergence and Adaptation of Chronic Wasting Disease Strains.

Degradation of Fungal Prion HET-s(218-289) Induces Formation of a Generic Amyloid Fold ⬇️

Destabilizing polymorphism in cervid prion protein hydrophobic core determines prion conformation and conversion efficiency

Diverse, evolving conformer populations drive distinct phenotypes in frontotemporal lobar degeneration caused by the same MAPT-P301L mutation

Eight prion strains have PrPSc molecules with different conformations ⬇️

Engineering a 2D protein-DNA crystal

Evolutionary descent of prion genes from the ZIP family of metal ion transporters

Family reunion--the ZIP/prion gene family

Full atomistic model of prion structure and conversion

Genes contributing to prion pathogenesis

Homogeneous nanodiscs of native membranes formed by stilbene-maleic-acid copolymers

In vitro conversion and seeded fibrillization of posttranslationally modified prion protein

Influence of water, fat, and glycerol on the mechanism of thermal prion inactivation

Microtubule-associated protein tau, paired helical filaments, and phosphorylation.

Molecular properties of complexes formed between the prion protein and synthetic peptides ⬇️

Native nanodiscs formed by styrene-maleic acid copolymer derivatives help recover infectious prion multimers bound to brain-derived lipids

Neuroinvasion of α-Synuclein Prionoids after Intraperitoneal and Intraglossal Inoculation.

Prion protein with a mutant N-terminal octarepeat region undergoes cobalamin-dependent assembly into high-molecular weight complexes

Prion uptake in the gut: identification of the first uptake and replication sites

Protease-Resistant Prions Selectively Decrease Shadoo Protein ⬇️

Scrapie infectivity is independent of amyloid staining properties of the N-terminally truncated prion protein

Secretory pathway retention of mutant prion protein induces p38-MAPK activation and lethal disease in mice

Self-assembling small molecules form nanofibrils that bind procaspase-3 to promote activation

Self-assembly of recombinant prion protein of 106 residues

Separation of scrapie prion infectivity from PrP amyloid polymers

Significance of native PLGA nanoparticles in the treatment of Alzheimer's disease pathology

Small-molecule aggregates inhibit amyloid polymerization

Solid-state NMR studies of the secondary structure of a mutant prion protein fragment of 55 residues that induces neurodegeneration

Somatostatin binds to the human amyloid β peptide and favors the formation of distinct oligomers

Structural studies of truncated forms of the prion protein PrP.

Subcellular distribution of the prion protein in sickness and in health

The CNS in inbred transgenic models of 4-repeat Tauopathy develops consistent tau seeding capacity yet focal and diverse patterns of protein deposition

The Detection of Infectious Prions: In Vitro Conversion Assays Change the (Folding) Landscape

The Structural Architecture of an Infectious Mammalian Prion Using Electron Cryomicroscopy

The Structure of Mammalian Prions and Their Aggregates

The Structure of PrPSc Prions

The Structure of the Infectious Prion Protein and Its Propagation

The ZIP5 ectodomain co-localizes with PrP and may acquire a PrP-like fold that assembles into a dimer

The chicken neural extracellular matrix molecule restrictin: similarity with EGF-, fibronectin type III-, and fibrinogen-like motifs

The human brain somatostatin interactome: SST binds selectively to P-type family ATPases

The structure of human prions: from biology to structural models-considerations and pitfalls

The structure of the infectious prion protein: experimental data and molecular models

Toll-like receptor-mediated immune response inhibits prion propagation.

α-Synuclein strains target distinct brain regions and cell types