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Lista de obras de Raquel T. Lima

A methanolic extract of Ganoderma lucidum fruiting body inhibits the growth of a gastric cancer cell line and affects cellular autophagy and cell cycle.

artículo científico publicado en 2014

A novel curcumin derivative which inhibits P-glycoprotein, arrests cell cycle and induces apoptosis in multidrug resistance cells.

artículo científico publicado en 2016

Aminodi(hetero)arylamines in the thieno[3,2-b]pyridine series: synthesis, effects in human tumor cells growth, cell cycle analysis, apoptosis and evaluation of toxicity using non-tumor cells.

artículo científico publicado en 2012

Anti-hepatocellular carcinoma activity using human HepG2 cells and hepatotoxicity of 6-substituted methyl 3-aminothieno[3,2-b]pyridine-2-carboxylate derivatives: in vitro evaluation, cell cycle analysis and QSAR studies.

artículo científico publicado en 2011

Bioactive xanthones with effect on P-glycoprotein and prediction of intestinal absorption

Can macroalgae provide promising anti-tumoral compounds? A closer look at Cystoseira tamariscifolia as a source for antioxidant and anti-hepatocarcinoma compounds

artículo científico publicado en 2016

Characterization and antitumor activity of the extracellular carbohydrate polymer from the cyanobacterium Synechocystis ΔsigF mutant

artículo científico publicado en 2019

Cordyceps militaris (L.) Link Fruiting Body Reduces the Growth of a Non-Small Cell Lung Cancer Cell Line by Increasing Cellular Levels of p53 and p21.

artículo científico publicado en 2015

Cytotoxicity and cell death mechanisms induced by a novel bisnaphthalimidopropyl derivative against the NCI-H460 non-small lung cancer cell line

artículo científico publicado en 2013

Data supporting the shedding of larger extracellular vesicles by multidrug resistant tumour cells.

artículo científico publicado en 2016

Deep Sequencing Analysis Reveals Distinctive Non-Coding RNAs When Comparing Tumor Multidrug-Resistant Cells and Extracellular Vesicles with Drug-Sensitive Counterparts

artículo científico publicado en 2020

Design and synthesis of new inhibitors of p53–MDM2 interaction with a chalcone scaffold

Development of noncytotoxic PLGA nanoparticles to improve the effect of a new inhibitor of p53-MDM2 interaction

artículo científico publicado en 2013

EBV interferes with the sensitivity of Burkitt lymphoma Akata cells to etoposide

artículo científico publicado en 2011

Effect of miR-128 in DNA damage of HL-60 acute myeloid leukemia cells.

artículo científico publicado en 2014

Efficient synthesis of 6-(hetero)arylthieno[3,2-b]pyridines by Suzuki-Miyaura coupling. Evaluation of growth inhibition on human tumor cell lines, SARs and effects on the cell cycle

artículo científico publicado en 2010

Enantiomeric resolution of albendazole sulfoxide by semipreparative HPLC and in vitro study of growth inhibitory effects on human cancer cell lines

artículo científico publicado en 2012

Flower extracts of Filipendula ulmaria (L.) Maxim inhibit the proliferation of the NCI-H460 tumour cell line

scholarly article in Industrial Crops and Products, vol. 59, August 2014

Identification of the metabolic alterations associated with the multidrug resistant phenotype in cancer and their intercellular transfer mediated by extracellular vesicles

scientific article published on 17 March 2017

Insights into the in vitro antitumor mechanism of action of a new pyranoxanthone.

artículo científico publicado en 2010

Intercellular Transfer of Cancer Drug Resistance Traits by Extracellular Vesicles

artículo científico

Liposomal therapies in oncology: does one size fit all?

artículo científico publicado en 2018

Methanolic Extract of Ganoderma lucidum Induces Autophagy of AGS Human Gastric Tumor Cells.

artículo científico publicado en 2015

MicroRNA regulation of core apoptosis pathways in cancer.

scientific article published on 08 December 2010

MicroRNAs in Cancer Drug Resistance and Drug Sensitivity

Modulation of Autophagy by a Thioxanthone Decreases the Viability of Melanoma Cells.

artículo científico publicado en 2016

Multidimensional optimization of promising antitumor xanthone derivatives.

artículo científico publicado en 2013

Multidrug resistant tumour cells shed more microvesicle-like EVs and less exosomes than their drug-sensitive counterpart cells

artículo científico publicado en 2015

Mutant fibrinogen A-α-chain associated with hereditary renal amyloidosis and peripheral neuropathy

artículo científico publicado en 2004

New di(hetero)arylethers and di(hetero)arylamines in the thieno[3,2-b]pyridine series: synthesis, growth inhibitory activity on human tumor cell lines and non-tumor cells, effects on cell cycle and on programmed cell death.

artículo científico publicado en 2013

OPNa Overexpression Is Associated with Matrix Calcification in Thyroid Cancer Cell Lines

artículo científico publicado en 2018

Potential small-molecule activators of caspase-7 identified using yeast-based caspase-3 and -7 screening assays

artículo científico publicado en 2014

Predictive Biomarkers and Patient Outcome in Platinum-Resistant (PLD-Treated) Ovarian Cancer

artículo científico publicado en 2020

Prenylated derivatives of baicalein and 3,7-dihydroxyflavone: synthesis and study of their effects on tumor cell lines growth, cell cycle and apoptosis.

artículo científico publicado en 2011

Pyranoxanthones: Synthesis, growth inhibitory activity on human tumor cell lines and determination of their lipophilicity in two membrane models

artículo científico publicado en 2013

Screening a Small Library of Xanthones for Antitumor Activity and Identification of a Hit Compound which Induces Apoptosis

artículo científico publicado en 2016

Simultaneous targeting of P-gp and XIAP with siRNAs increases sensitivity of P-gp overexpressing CML cells to imatinib.

artículo científico publicado en 2011

Solid-phase synthesis of 2'-hydroxychalcones. Effects on cell growth inhibition, cell cycle and apoptosis of human tumor cell lines

artículo científico publicado en 2011

Specific downregulation of bcl-2 and xIAP by RNAi enhances the effects of chemotherapeutic agents in MCF-7 human breast cancer cells.

artículo científico publicado en 2004

Structure based design, synthesis, and evaluation of potential inhibitors of steroid sulfatase

artículo científico publicado en 2014

Suillus luteus methanolic extract inhibits proliferation and increases expression of p-H2A.X in a non-small cell lung cancer cell line

Sulfated small molecules targeting eBV in Burkitt lymphoma: from in silico screening to the evidence of in vitro effect on viral episomal DNA.

artículo científico publicado en 2013

Suppression of spindly delays mitotic exit and exacerbates cell death response of cancer cells treated with low doses of paclitaxel

artículo científico publicado en 2017

Synthesis and Evaluation of the Tumor Cell Growth Inhibitory Potential of New Putative HSP90 Inhibitors.

artículo científico publicado en 2018

Synthesis of a natural chalcone and its prenyl analogs--evaluation of tumor cell growth-inhibitory activities, and effects on cell cycle and apoptosis

artículo científico publicado en 2012

Targeting miR-21 induces autophagy and chemosensitivity of leukemia cells.

artículo científico publicado en 2013

The Antitumor Activity of a Lead Thioxanthone is Associated with Alterations in Cholesterol Localization

artículo científico publicado en 2018

The network of P-glycoprotein and microRNAs interactions

artículo científico publicado en 2013

Treatment of Akata EBV-positive cells with doxorubicin causes more EBV reactivation than treatment with etoposide

artículo científico publicado en 2011

miR-143 overexpression impairs growth of human colon carcinoma xenografts in mice with induction of apoptosis and inhibition of proliferation

artículo científico publicado en 2011

An Aqueous Extract of Tuberaria lignosa Inhibits Cell Growth, Alters the Cell Cycle Profile, and Induces Apoptosis of NCI-H460 Tumor Cells

artículo científico publicado en 2016

Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition)

artículo científico publicado en 2016