Lista de obras - Louis Vermeulen - Dominio Público Uruguay

A cancer drug atlas enables synergistic targeting of independent drug vulnerabilities

artículo científico publicado en 2020

A marker-independent lineage-tracing system to quantify clonal dynamics and stem cell functionality in cancer tissue

artículo científico publicado en 2019

A mouse model for peritoneal metastases of colorectal origin recapitulates patient heterogeneity

artículo científico publicado en 2020

A multidimensional network approach reveals microRNAs as determinants of the mesenchymal colorectal cancer subtype.

artículo científico publicado en 2016

Assessing the carcinogenic potential of low-dose exposures to chemical mixtures in the environment: the challenge ahead

artículo científico publicado en 2015

Associations of non-pedunculated T1 colorectal adenocarcinoma outcome with consensus molecular subtypes, immunoscore, and microsatellite status: a multicenter case-cohort study

artículo científico publicado en 2020

Bcl-2 is a critical mediator of intestinal transformation

artículo científico publicado en 2016

Bidirectional interconversion of stem and non-stem cancer cell populations: A reassessment of theoretical models for tumor heterogeneity

artículo científico publicado en 2015

CD44 expression in intestinal epithelium and colorectal cancer is independent of p53 status

artículo científico publicado en 2013

CFTR is a tumor suppressor gene in murine and human intestinal cancer

artículo científico publicado en 2016

Cancer heterogeneity--a multifaceted view

artículo científico publicado en 2013

Cancer stem cell tumor model reveals invasive morphology and increased phenotypical heterogeneity.

artículo científico publicado en 2010

Cancer stem cells--old concepts, new insights.

artículo científico publicado en 2008

Chromosomal copy number heterogeneity predicts survival rates across cancers

artículo científico publicado en 2021

Collagen-rich stroma in aggressive colon tumors induces mesenchymal gene expression and tumor cell invasion

artículo científico publicado en 2016

Colon cancer stem cells dictate tumor growth and resist cell death by production of interleukin-4.

artículo científico publicado en 2007

Colorectal cancer heterogeneity and targeted therapy: a case for molecular disease subtypes

artículo científico publicado en 2015

Consensus molecular subtypes of colorectal cancer are recapitulated in in vitro and in vivo models

artículo científico publicado en 2018

Continuous clonal labeling reveals small numbers of functional stem cells in intestinal crypts and adenomas.

artículo científico publicado en 2013

Correction: Integrative network biology analysis identifies miR-508-3p as the determinant for the mesenchymal identity and a strong prognostic biomarker of ovarian cancer

scientific article published on 01 November 2019

Defining stem cell dynamics in models of intestinal tumor initiation.

artículo científico publicado en 2013

Dissecting cancer heterogeneity--an unsupervised classification approach

artículo científico publicado en 2013

ER-Stress-Induced Differentiation Sensitizes Colon Cancer Stem Cells to Chemotherapy

artículo científico publicado en 2015

Exploiting KRAS-mediated metabolic reprogramming as a therapeutic target

artículo científico publicado en 2021

Exploring cancer stem cell niche directed tumor growth.

artículo científico publicado en 2010

Fusion of intestinal epithelial cells with bone marrow derived cells is dispensable for tissue homeostasis.

artículo científico publicado en 2012

Integrative network biology analysis identifies miR-508-3p as the determinant for the mesenchymal identity and a strong prognostic biomarker of ovarian cancer

artículo científico publicado en 2018

Interconnectivity between molecular subtypes and tumor stage in colorectal cancer

artículo científico publicado en 2020

Intestinal label-retaining cells are secretory precursors expressing Lgr5.

artículo científico publicado en 2013

Intestinal region-specific Wnt signalling profiles reveal interrelation between cell identity and oncogenic pathway activity in cancer development

scientific article published on 03 December 2020

Keeping stem cells in check: a hippo balancing act

artículo científico publicado en 2013

Methylation of cancer-stem-cell-associated Wnt target genes predicts poor prognosis in colorectal cancer patients

artículo científico publicado en 2011

Microenvironmental regulation of stem cells in intestinal homeostasis and cancer

scientific article published on 15 June 2011

Modeling evolutionary dynamics of epigenetic mutations in hierarchically organized tumors

artículo científico publicado en 2011

Mutations in the Ras-Raf Axis underlie the prognostic value of CD133 in colorectal cancer

artículo científico publicado en 2012

One renegade cancer stem cell?

artículo científico publicado en 2009

Polycomb complex PRC1 as gatekeeper of intestinal stem cell identity

artículo científico publicado en 2016

Practical and Robust Identification of Molecular Subtypes in Colorectal Cancer by Immunohistochemistry

artículo científico publicado en 2016

Reconciliation of classification systems defining molecular subtypes of colorectal cancer: interrelationships and clinical implications.

artículo científico publicado en 2014

Serrated neoplasia-role in colorectal carcinogenesis and clinical implications

artículo científico

Stem cell competition: how speeding mutants beat the rest

artículo científico publicado en 2014

Stem cell dynamics in homeostasis and cancer of the intestine

artículo científico publicado en 2014

Stem cell functionality is microenvironmentally defined during tumour expansion and therapy response in colon cancer.

artículo científico publicado en 2018

TGFβ signaling directs serrated adenomas to the mesenchymal colorectal cancer subtype

artículo científico publicado en 2016

Targeting Wnt signaling in colon cancer stem cells

scientific article published on 15 December 2010

The Use of Targeted Therapies for Precision Medicine in Oncology.

artículo científico publicado en 2016

The consensus molecular subtypes of colorectal cancer

artículo científico publicado en 2015

The developing cancer stem-cell model: clinical challenges and opportunities

artículo científico publicado en 2012

The effect of environmental chemicals on the tumor microenvironment

artículo científico publicado en 2015

Turning off the BCL-2 switch to prevent intestinal tumorigenesis

artículo científico publicado en 2016

Wnt Signaling in Cancer Stem Cell Biology

artículo científico publicado en 2016

Wnt activity defines colon cancer stem cells and is regulated by the microenvironment

artículo científico publicado en 2010

Lista de obras de Louis Vermeulen

A cancer drug atlas enables synergistic targeting of independent drug vulnerabilities

A marker-independent lineage-tracing system to quantify clonal dynamics and stem cell functionality in cancer tissue

A mouse model for peritoneal metastases of colorectal origin recapitulates patient heterogeneity

A multidimensional network approach reveals microRNAs as determinants of the mesenchymal colorectal cancer subtype.

Assessing the carcinogenic potential of low-dose exposures to chemical mixtures in the environment: the challenge ahead

Associations of non-pedunculated T1 colorectal adenocarcinoma outcome with consensus molecular subtypes, immunoscore, and microsatellite status: a multicenter case-cohort study

Bcl-2 is a critical mediator of intestinal transformation

Bidirectional interconversion of stem and non-stem cancer cell populations: A reassessment of theoretical models for tumor heterogeneity

CD44 expression in intestinal epithelium and colorectal cancer is independent of p53 status

CFTR is a tumor suppressor gene in murine and human intestinal cancer

Cancer heterogeneity--a multifaceted view

Cancer stem cell tumor model reveals invasive morphology and increased phenotypical heterogeneity.

Cancer stem cells--old concepts, new insights.

Chromosomal copy number heterogeneity predicts survival rates across cancers

Collagen-rich stroma in aggressive colon tumors induces mesenchymal gene expression and tumor cell invasion

Colon cancer stem cells dictate tumor growth and resist cell death by production of interleukin-4.

Colorectal cancer heterogeneity and targeted therapy: a case for molecular disease subtypes

Consensus molecular subtypes of colorectal cancer are recapitulated in in vitro and in vivo models

Continuous clonal labeling reveals small numbers of functional stem cells in intestinal crypts and adenomas.

Correction: Integrative network biology analysis identifies miR-508-3p as the determinant for the mesenchymal identity and a strong prognostic biomarker of ovarian cancer

Defining stem cell dynamics in models of intestinal tumor initiation.

Dissecting cancer heterogeneity--an unsupervised classification approach

ER-Stress-Induced Differentiation Sensitizes Colon Cancer Stem Cells to Chemotherapy

Exploiting KRAS-mediated metabolic reprogramming as a therapeutic target

Exploring cancer stem cell niche directed tumor growth.

Fusion of intestinal epithelial cells with bone marrow derived cells is dispensable for tissue homeostasis.

Integrative network biology analysis identifies miR-508-3p as the determinant for the mesenchymal identity and a strong prognostic biomarker of ovarian cancer

Interconnectivity between molecular subtypes and tumor stage in colorectal cancer

Intestinal label-retaining cells are secretory precursors expressing Lgr5.

Intestinal region-specific Wnt signalling profiles reveal interrelation between cell identity and oncogenic pathway activity in cancer development

Keeping stem cells in check: a hippo balancing act

Methylation of cancer-stem-cell-associated Wnt target genes predicts poor prognosis in colorectal cancer patients

Microenvironmental regulation of stem cells in intestinal homeostasis and cancer

Modeling evolutionary dynamics of epigenetic mutations in hierarchically organized tumors

Mutations in the Ras-Raf Axis underlie the prognostic value of CD133 in colorectal cancer

One renegade cancer stem cell?

Polycomb complex PRC1 as gatekeeper of intestinal stem cell identity

Practical and Robust Identification of Molecular Subtypes in Colorectal Cancer by Immunohistochemistry

Reconciliation of classification systems defining molecular subtypes of colorectal cancer: interrelationships and clinical implications.

Serrated neoplasia-role in colorectal carcinogenesis and clinical implications

Stem cell competition: how speeding mutants beat the rest

Stem cell dynamics in homeostasis and cancer of the intestine

Stem cell functionality is microenvironmentally defined during tumour expansion and therapy response in colon cancer.

TGFβ signaling directs serrated adenomas to the mesenchymal colorectal cancer subtype

Targeting Wnt signaling in colon cancer stem cells

The Use of Targeted Therapies for Precision Medicine in Oncology.

The consensus molecular subtypes of colorectal cancer

The developing cancer stem-cell model: clinical challenges and opportunities

The effect of environmental chemicals on the tumor microenvironment

Turning off the BCL-2 switch to prevent intestinal tumorigenesis

Wnt Signaling in Cancer Stem Cell Biology

Wnt activity defines colon cancer stem cells and is regulated by the microenvironment