Lista de obras - Malgorzata Czyz - Dominio Público Uruguay

17-Aminogeldanamycin Inhibits Constitutive Nuclear Factor-Kappa B (NF-κB) Activity in Patient-Derived Melanoma Cell Lines

artículo científico publicado en 2020

17-Aminogeldanamycin selectively diminishes IRE1α-XBP1s pathway activity and cooperatively induces apoptosis with MEK1/2 and BRAFV600E inhibitors in melanoma cells of different genetic subtypes

scientific article published on 01 August 2019

A non-apoptotic function of caspase-3 in pharmacologically-induced differentiation of K562 cells.

artículo científico publicado en 2009

Accumulation of gamma-globin mRNA and induction of irreversible erythroid differentiation after treatment of CML cell line K562 with new doxorubicin derivatives

artículo científico

Actinomycin D specifically inhibits the interaction between transcription factor Sp1 and its binding site

artículo científico publicado en 1998

Anti-apoptotic proteins on guard of melanoma cell survival ⬇️

artículo científico publicado el 20 de enero de 2013

Aspirin--the prodigious panacea? Molecular mechanisms of the action of acetylsalicylic acid in the organism

artículo científico publicado en 2005

Autoregulation of GAL4 transcription is essential for rapid growth of Kluyveromyces lactis on lactose and galactose

artículo científico

BCL-w: apoptotic and non-apoptotic role in health and disease

scientific article published on 21 April 2020

BH3 mimetics as a strategy to complement anticancer therapies

artículo científico publicado en 2012

BH3 mimetics potentiate pro-apoptotic activity of encorafenib in BRAF<sup>V600E</sup> melanoma cells

artículo científico publicado en 2020

BRAF mutation in progression and therapy of melanoma, papillary thyroid carcinoma and colorectal adenocarcinoma

artículo científico publicado en 2016

Biological evaluation of novel Pt(II) and Pd(II) complexes with pyrazole-containing ligands

artículo científico publicado en 2004

Cell context-dependent activities of parthenolide in primary and metastatic melanoma cells

artículo científico publicado en 2010

Combined effects of doxorubicin and STI571 on growth, differentiation and apoptosis of CML cell line K562.

artículo científico publicado en 2007

Copper(II) complexes with derivatives of pyrazole as potential antioxidant enzyme mimics.

artículo científico publicado en 2012

Cytotoxic effect, differentiation, inhibition of growth and theoretical calculations of an N,N-donor ligands and its platinum(II), palladium(II) and copper(II) complexes

artículo científico publicado en 2007

Dacarbazine, a chemotherapeutic against metastatic melanoma and a reference drug for new treatment modalities

artículo científico publicado en 2011

Deciphering the Functional Role of RIPK4 in Melanoma

artículo científico publicado en 2021

Diminution of miR-340-5p levels is responsible for increased expression of ABCB5 in melanoma cells under oxygen-deprived conditions.

artículo científico publicado en 2015

Dissecting Mechanisms of Melanoma Resistance to BRAF and MEK Inhibitors Revealed Genetic and Non-Genetic Patient- and Drug-Specific Alterations and Remarkable Phenotypic Plasticity

scientific article published on 07 January 2020

Effect of 8-methoxypsoralen and 4,5'-dimethylangelicin on ribonucleic acid synthesis in vitro

artículo científico publicado en 1988

Effects of anthracycline derivatives on human leukemia K562 cell growth and differentiation.

artículo científico publicado en 2005

Effects of anticancer drugs on transcription factor-DNA interactions.

artículo científico publicado en 2005

Effects of anticancer drugs on transcription in vitro.

artículo científico publicado en 2001

Elevated cholesterol reduces acetylsalicylic acid-mediated platelet acetylation

artículo científico publicado en 2007

Evaluation of selected angiogenic and inflammatory markers in endometriosis before and after danazol treatment

artículo científico publicado en 2014

Evidence of inhibition of DNA methylation by fludarabine

artículo científico publicado en 2000

Exogenous growth factors bFGF, EGF and HGF do not influence viability and phenotype of V600EBRAF melanoma cells and their response to vemurafenib and trametinib in vitro

artículo científico publicado en 2017

Expression of miRNAs as Important Element of Melanoma Cell Plasticity in Response to Microenvironmental Stimuli

artículo científico publicado en 2015

Fibroblast Growth Factor Receptor Signaling in Skin Cancers

scientific article published on 04 June 2019

GATA-1 binding to the alphaV promoter negatively regulates expression of the integrin alphaV subunit in human leukemic K562 cells.

artículo científico publicado en 2002

Gene expression profiling identifies microphthalmia-associated transcription factor (MITF) and Dickkopf-1 (DKK1) as regulators of microenvironment-driven alterations in melanoma phenotype

artículo científico publicado en 2014

HGF/c-MET Signaling in Melanocytes and Melanoma

artículo científico publicado en 2018

Increased protein glycation in diabetes mellitus is associated with decreased aspirin-mediated protein acetylation and reduced sensitivity of blood platelets to aspirin

artículo científico publicado en 2005

Induced differentiation of the K562 leukemic cell line

artículo científico publicado en 2005

Inhibition of DNA Methylation by 5-Aza-2′-Deoxycytidine Correlates with Induction of K562 Cells Differentiation ⬇️

artículo científico publicado el 1 de enero de 2000

Inhibition of DNA-dependent RNA synthesis by 8-methoxypsoralen

artículo científico publicado en 1988

Inhibition of RNA synthesis in vitro by 9-aminoacridine carboxamide antitumor agents. Effects on overall RNA synthesis and synthesis of the initiating dinucleotide

artículo científico publicado en 1990

Inhibition of RNA synthesis in vitro by acridines--relation between structure and activity.

artículo científico publicado en 1998

Inhibitors of HSP90 in melanoma

scientific article published on 01 February 2020

Insulin Reduces the Efficacy of Vemurafenib and Trametinib in Melanoma Cells

artículo científico publicado en 2020

MCL-1, BCL-XL and MITF Are Diversely Employed in Adaptive Response of Melanoma Cells to Changes in Microenvironment

artículo científico publicado en 2015

MITF in melanoma: mechanisms behind its expression and activity.

artículo científico publicado en 2014

Melanoma-Derived Extracellular Vesicles Bear the Potential for the Induction of Antigen-Specific Tolerance

artículo científico publicado el 2 de julio de 2019

MiRNA in melanoma-derived exosomes

artículo científico publicado en 2014

Modulation of WNT/β-catenin pathway in melanoma by biologically active components derived from plants.

artículo científico publicado en 2016

Molecular mechanisms of anthracyclines action

artículo científico publicado en 2006

Molecular mechanisms of parthenolide's action: Old drug with a new face

artículo científico publicado en 2010

Natural compounds' activity against cancer stem-like or fast-cycling melanoma cells

artículo científico publicado en 2014

Novel inhibitors of Bcr-Abl

scientific article published on 01 January 2006

PARP1 inhibitor olaparib (Lynparza) exerts synthetic lethal effect against ligase 4-deficient melanomas.

artículo científico publicado en 2016

Parthenolide as Cooperating Agent for Anti-Cancer Treatment of Various Malignancies

artículo científico publicado en 2020

Parthenolide complements the cell death-inducing activity of doxorubicin in melanoma cells

artículo científico publicado en 2013

Parthenolide enhances dacarbazine activity against melanoma cells

artículo científico publicado en 2013

Parthenolide induces MITF-M downregulation and senescence in patient-derived MITF-M(high) melanoma cell populations

artículo científico publicado en 2016

Parthenolide reduces the frequency of ABCB5-positive cells and clonogenic capacity of melanoma cells from anchorage independent melanospheres.

artículo científico publicado en 2012

Parthenolide, a sesquiterpene lactone from the medical herb feverfew, shows anticancer activity against human melanoma cells in vitro.

artículo científico publicado en 2010

Pentoxifylline Inhibits WNT Signalling in β-Cateninhigh Patient-Derived Melanoma Cell Populations

artículo científico publicado en 2016

Phenotypic diversity of patient-derived melanoma populations in stem cell medium.

artículo científico publicado en 2015

Physiologically Relevant Oxygen Concentration (6% O2) as an Important Component of the Microenvironment Impacting Melanoma Phenotype and Melanoma Response to Targeted Therapeutics In Vitro ⬇️

scientific article published on 27 August 2019

Plasticity of Drug-Naïve and Vemurafenib- or Trametinib-Resistant Melanoma Cells in Execution of Differentiation/Pigmentation Program

artículo científico publicado en 2019

Potentiation of arsenic trioxide cytotoxicity by Parthenolide and buthionine sulfoximine in murine and human leukemic cells

artículo científico publicado en 2007

Pro-apoptotic Activity of BH3-only Proteins and BH3 Mimetics: from Theory to Potential Cancer Therapy ⬇️

artículo científico publicado el 1 de octubre de 2012

Pro-survival role of MITF in melanoma

artículo científico publicado en 2014

Proteomics in human cancer research

artículo científico publicado en 2006

Psoralens as probes in the study of the structure and function of nucleic acids

artículo científico publicado en 1989

Regulation of the Tissue Factor Promoter in Endothelial Cells

artículo científico publicado en 1995

Role of miRNAs in Melanoma Metastasis

artículo científico publicado en 2019

STI571 and morpholine derivative of doxorubicin collaborate in inhibition of K562 cell proliferation by inducing differentiation and mitochondrial pathway of apoptosis

artículo científico publicado en 2008

STI571/doxorubicin concentration-dependent switch for diverse caspase actions in CML cell line K562.

artículo científico publicado en 2008

STI571: a summary of targeted therapy

artículo científico publicado en 2006

Selective Sp1 and Sp3 binding is crucial for activity of the integrin alphaV promoter in cultured endothelial cells

artículo científico publicado en 1999

Sequence specificity of formaldehyde-mediated covalent binding of anthracycline derivatives to DNA.

artículo científico publicado en 2005

Specificity and selectivity of the NFkappaB response

artículo científico publicado en 2005

Sphere formation and self-renewal capacity of melanoma cells is affected by the microenvironment

artículo científico publicado en 2012

Structural and Biofunctional Insights into the Cyclo(Pro-Pro-Phe-Phe-) Scaffold from Experimental and In Silico Studies: Melanoma and Beyond

artículo científico publicado en 2022

Superoxide dismutase mimetics: possible clinical applications

artículo científico publicado en 2008

Synthesis and biological evaluation of new bischromone derivatives with antiproliferative activity

artículo científico publicado en 2012

Synthesis and in vitro biological evaluation of new polyamine conjugates as potential anticancer drugs

artículo científico publicado en 2010

Synthesis, X-ray structure, electrochemical properties and cytotoxic effects of new arene ruthenium(II) complexes

Synthesis, physico-chemical properties and biological analysis of newly obtained copper(II) complexes with pyrazole derivatives

artículo científico publicado en 2014

Synthesis, structure, electrochemical properties, cytotoxic effects and antioxidant activity of 5-amino-8-methyl-4H-benzopyran-4-one and its copper(II) complexes

artículo científico publicado en 2012

Synthesis, structure, physico-chemical and biological properties of metal(II) complexes with 5-amino-8-methyl-4H-benzopyran-4-one

artículo científico publicado en 2014

TGF-β signaling pathways in cancers ⬇️

artículo científico publicado el 25 de septiembre de 2013

TYRP1 mRNA level is stable and MITF-M-independent in drug-naïve, vemurafenib- and trametinib-resistant BRAFV600E melanoma cells

scientific article published on 17 October 2019

Targeting NF-κB and HIF-1 pathways for the treatment of cancer: part I.

scientific article published on 28 May 2011

Targeting NF-κB and HIF-1 pathways for the treatment of cancer: part II.

artículo científico publicado en 2011

Tautomerization of 2-nitroso-N-arylanilines by coordination as N,N'-chelate ligands to rhenium(I) complexes and the anticancer activity of newly synthesized oximine rhenium(I) complexes against human melanoma and leukemia cells in vitro

artículo científico publicado en 2010

The Functional Role of Long Non-Coding RNAs in Melanoma

artículo científico publicado en 2021

The effect of a platelet cholesterol modulation on the acetylsalicylic acid-mediated blood platelet inhibition in hypercholesterolemic patients

artículo científico publicado en 2011

The heterogeneous immune microenvironment in breast cancer is affected by hypoxia-related genes

artículo científico publicado en 2013

The synthesis, lipophilicity and cytotoxic effects of new ruthenium(II) arene complexes with chromone derivatives.

artículo científico publicado en 2016

Thymosin beta 4 induces the synthesis of plasminogen activator inhibitor 1 in cultured endothelial cells and increases its extracellular expression

artículo científico publicado en 2003

Transcription factors as targets for DNA-interacting drugs.

artículo científico publicado en 2003

Transcription factors as targets of anticancer drugs.

artículo científico publicado en 1999

Transcription factors in the development and progression of melanoma

artículo científico publicado en 2007

Vemurafenib and trametinib reduce expression of CTGF and IL-8 in V600EBRAF melanoma cells

artículo científico publicado en 2017

WNT Signaling in Melanoma

artículo científico publicado en 2020

Whole-exome sequencing reveals novel genetic variants associated with diverse phenotypes of melanoma cells

scientific article published on 06 January 2019

miRNAs in Melanoma: Tumor Suppressors and Oncogenes with Prognostic Potential

artículo científico publicado en 2016

Lista de obras de Malgorzata Czyz

17-Aminogeldanamycin Inhibits Constitutive Nuclear Factor-Kappa B (NF-κB) Activity in Patient-Derived Melanoma Cell Lines

17-Aminogeldanamycin selectively diminishes IRE1α-XBP1s pathway activity and cooperatively induces apoptosis with MEK1/2 and BRAFV600E inhibitors in melanoma cells of different genetic subtypes

A non-apoptotic function of caspase-3 in pharmacologically-induced differentiation of K562 cells.

Accumulation of gamma-globin mRNA and induction of irreversible erythroid differentiation after treatment of CML cell line K562 with new doxorubicin derivatives

Actinomycin D specifically inhibits the interaction between transcription factor Sp1 and its binding site

Anti-apoptotic proteins on guard of melanoma cell survival ⬇️

Aspirin--the prodigious panacea? Molecular mechanisms of the action of acetylsalicylic acid in the organism

Autoregulation of GAL4 transcription is essential for rapid growth of Kluyveromyces lactis on lactose and galactose

BCL-w: apoptotic and non-apoptotic role in health and disease

BH3 mimetics as a strategy to complement anticancer therapies

BH3 mimetics potentiate pro-apoptotic activity of encorafenib in BRAF<sup>V600E</sup> melanoma cells

BRAF mutation in progression and therapy of melanoma, papillary thyroid carcinoma and colorectal adenocarcinoma

Biological evaluation of novel Pt(II) and Pd(II) complexes with pyrazole-containing ligands

Cell context-dependent activities of parthenolide in primary and metastatic melanoma cells

Combined effects of doxorubicin and STI571 on growth, differentiation and apoptosis of CML cell line K562.

Copper(II) complexes with derivatives of pyrazole as potential antioxidant enzyme mimics.

Cytotoxic effect, differentiation, inhibition of growth and theoretical calculations of an N,N-donor ligands and its platinum(II), palladium(II) and copper(II) complexes

Dacarbazine, a chemotherapeutic against metastatic melanoma and a reference drug for new treatment modalities

Deciphering the Functional Role of RIPK4 in Melanoma

Diminution of miR-340-5p levels is responsible for increased expression of ABCB5 in melanoma cells under oxygen-deprived conditions.

Dissecting Mechanisms of Melanoma Resistance to BRAF and MEK Inhibitors Revealed Genetic and Non-Genetic Patient- and Drug-Specific Alterations and Remarkable Phenotypic Plasticity

Effect of 8-methoxypsoralen and 4,5'-dimethylangelicin on ribonucleic acid synthesis in vitro

Effects of anthracycline derivatives on human leukemia K562 cell growth and differentiation.

Effects of anticancer drugs on transcription factor-DNA interactions.

Effects of anticancer drugs on transcription in vitro.

Elevated cholesterol reduces acetylsalicylic acid-mediated platelet acetylation

Evaluation of selected angiogenic and inflammatory markers in endometriosis before and after danazol treatment

Evidence of inhibition of DNA methylation by fludarabine

Exogenous growth factors bFGF, EGF and HGF do not influence viability and phenotype of V600EBRAF melanoma cells and their response to vemurafenib and trametinib in vitro

Expression of miRNAs as Important Element of Melanoma Cell Plasticity in Response to Microenvironmental Stimuli

Fibroblast Growth Factor Receptor Signaling in Skin Cancers

GATA-1 binding to the alphaV promoter negatively regulates expression of the integrin alphaV subunit in human leukemic K562 cells.

Gene expression profiling identifies microphthalmia-associated transcription factor (MITF) and Dickkopf-1 (DKK1) as regulators of microenvironment-driven alterations in melanoma phenotype

HGF/c-MET Signaling in Melanocytes and Melanoma

Increased protein glycation in diabetes mellitus is associated with decreased aspirin-mediated protein acetylation and reduced sensitivity of blood platelets to aspirin

Induced differentiation of the K562 leukemic cell line

Inhibition of DNA Methylation by 5-Aza-2′-Deoxycytidine Correlates with Induction of K562 Cells Differentiation ⬇️

Inhibition of DNA-dependent RNA synthesis by 8-methoxypsoralen

Inhibition of RNA synthesis in vitro by 9-aminoacridine carboxamide antitumor agents. Effects on overall RNA synthesis and synthesis of the initiating dinucleotide

Inhibition of RNA synthesis in vitro by acridines--relation between structure and activity.

Inhibitors of HSP90 in melanoma

Insulin Reduces the Efficacy of Vemurafenib and Trametinib in Melanoma Cells

MCL-1, BCL-XL and MITF Are Diversely Employed in Adaptive Response of Melanoma Cells to Changes in Microenvironment

MITF in melanoma: mechanisms behind its expression and activity.

Melanoma-Derived Extracellular Vesicles Bear the Potential for the Induction of Antigen-Specific Tolerance

MiRNA in melanoma-derived exosomes

Modulation of WNT/β-catenin pathway in melanoma by biologically active components derived from plants.

Molecular mechanisms of anthracyclines action

Molecular mechanisms of parthenolide's action: Old drug with a new face

Natural compounds' activity against cancer stem-like or fast-cycling melanoma cells

Novel inhibitors of Bcr-Abl

PARP1 inhibitor olaparib (Lynparza) exerts synthetic lethal effect against ligase 4-deficient melanomas.

Parthenolide as Cooperating Agent for Anti-Cancer Treatment of Various Malignancies

Parthenolide complements the cell death-inducing activity of doxorubicin in melanoma cells

Parthenolide enhances dacarbazine activity against melanoma cells

Parthenolide induces MITF-M downregulation and senescence in patient-derived MITF-M(high) melanoma cell populations

Parthenolide reduces the frequency of ABCB5-positive cells and clonogenic capacity of melanoma cells from anchorage independent melanospheres.

Parthenolide, a sesquiterpene lactone from the medical herb feverfew, shows anticancer activity against human melanoma cells in vitro.

Pentoxifylline Inhibits WNT Signalling in β-Cateninhigh Patient-Derived Melanoma Cell Populations

Phenotypic diversity of patient-derived melanoma populations in stem cell medium.

Physiologically Relevant Oxygen Concentration (6% O2) as an Important Component of the Microenvironment Impacting Melanoma Phenotype and Melanoma Response to Targeted Therapeutics In Vitro ⬇️

Plasticity of Drug-Naïve and Vemurafenib- or Trametinib-Resistant Melanoma Cells in Execution of Differentiation/Pigmentation Program

Potentiation of arsenic trioxide cytotoxicity by Parthenolide and buthionine sulfoximine in murine and human leukemic cells

Pro-apoptotic Activity of BH3-only Proteins and BH3 Mimetics: from Theory to Potential Cancer Therapy ⬇️

Pro-survival role of MITF in melanoma

Proteomics in human cancer research

Psoralens as probes in the study of the structure and function of nucleic acids

Regulation of the Tissue Factor Promoter in Endothelial Cells

Role of miRNAs in Melanoma Metastasis

STI571 and morpholine derivative of doxorubicin collaborate in inhibition of K562 cell proliferation by inducing differentiation and mitochondrial pathway of apoptosis

STI571/doxorubicin concentration-dependent switch for diverse caspase actions in CML cell line K562.

STI571: a summary of targeted therapy

Selective Sp1 and Sp3 binding is crucial for activity of the integrin alphaV promoter in cultured endothelial cells

Sequence specificity of formaldehyde-mediated covalent binding of anthracycline derivatives to DNA.

Specificity and selectivity of the NFkappaB response

Sphere formation and self-renewal capacity of melanoma cells is affected by the microenvironment

Structural and Biofunctional Insights into the Cyclo(Pro-Pro-Phe-Phe-) Scaffold from Experimental and In Silico Studies: Melanoma and Beyond

Superoxide dismutase mimetics: possible clinical applications

Synthesis and biological evaluation of new bischromone derivatives with antiproliferative activity