Lista de obras - Dimitrios Morikis - Dominio Público Uruguay

1H resonance assignments and secondary structure of the carbon monoxide complex of soybean leghemoglobin determined by homonuclear two-dimensional and three-dimensional NMR spectroscopy

scientific article published on 01 January 1994

A New Generation of Potent Complement Inhibitors of the Compstatin Family ⬇️

artículo científico publicado el 26 de abril de 2011

A computational model for the evaluation of complement system regulation under homeostasis, disease, and drug intervention.

artículo científico publicado en 2018

A gain-of-function mutation of Arabidopsis lipid transfer protein 5 disturbs pollen tube tip growth and fertilization

artículo científico publicado en 2009

A multifaceted study of stigma/style cysteine-rich adhesin (SCA)-like Arabidopsis lipid transfer proteins (LTPs) suggests diversified roles for these LTPs in plant growth and reproduction

artículo científico publicado en 2010

A novel mechanism of PKA anchoring revealed by solution structures of anchoring complexes

artículo científico publicado en 2001

A predictive model for HIV type 1 coreceptor selectivity

artículo científico publicado en 2013

A theoretical view of the C3d:CR2 binding controversy.

artículo científico publicado en 2014

Alteration of sperm whale myoglobin heme axial ligation by site-directed mutagenesis

artículo científico publicado en 1990

An evaluation of Poisson-Boltzmann electrostatic free energy calculations through comparison with experimental mutagenesis data.

artículo científico publicado en 2011

Automated computational framework for the analysis of electrostatic similarities of proteins

artículo científico publicado en 2011

Clustering of HIV-1 Subtypes Based on gp120 V3 Loop electrostatic properties ⬇️

artículo científico publicado el 7 de febrero de 2012

Complement: structure, functions, evolution, and viral molecular mimicry

artículo científico publicado en 2003

Compstatin, a peptide inhibitor of complement, exhibits species-specific binding to complement component C3.

artículo científico publicado en 2003

Computational studies of CXCR1, the receptor of IL-8/CXCL8, using molecular dynamics and electrostatics

artículo científico publicado en 2008

Conformational analysis of compstatin analogues with molecular dynamics simulations in explicit water

artículo científico publicado en 2007

Conformational interconversion in compstatin probed with molecular dynamics simulations

artículo científico publicado en 2003

Conformational interconversion in protein crystals

artículo científico publicado el 5 de marzo de 1992

Contribution of specific amino acid changes in penicillin binding protein 1 to amoxicillin resistance in clinical Helicobacter pylori isolates

artículo científico publicado en 2010

De novo peptide design with C3a receptor agonist and antagonist activities: theoretical predictions and experimental validation

artículo científico publicado en 2012

Derivation of ligands for the complement C3a receptor from the C-terminus of C5a

artículo científico publicado en 2014

Design and NMR characterization of active analogues of compstatin containing non-natural amino acids

artículo científico publicado en 2005

Design of a modified mouse protein with ligand binding properties of its human analog by molecular dynamics simulations: the case of C3 inhibition by compstatin

artículo científico publicado en 2011

Development of a quasi-dynamic pharmacophore model for anti-complement peptide analogues

artículo científico publicado en 2005

Electrostatic Similarity Determination Using Multiresolution Analysis

artículo científico publicado en 2011

Electrostatic clustering and free energy calculations provide a foundation for protein design and optimization.

artículo científico publicado en 2010

Electrostatic exploration of the C3d-FH4 interaction using a computational alanine scan

artículo científico publicado en 2011

Electrostatic properties of the structure of the docking and dimerization domain of protein kinase A IIalpha

artículo científico publicado en 2002

Engineering pre-SUMO4 as efficient substrate of SENP2.

scientific article published on April 2014

Factor H-Inspired Design of Peptide Biomarkers of the Complement C3d Protein

artículo científico publicado en 2020

Hydration of the partially folded peptide RN-24 studied by multidimensional NMR.

artículo científico publicado en 1995

Immunophysical exploration of C3d-CR2(CCP1-2) interaction using molecular dynamics and electrostatics

artículo científico publicado en 2007

Influence of electrostatics on the complement regulatory functions of Kaposica, the complement inhibitor of Kaposi's sarcoma-associated herpesvirus

artículo científico publicado en 2010

Insights into the mechanism of C5aR inhibition by PMX53 via implicit solvent molecular dynamics simulations and docking

artículo científico publicado en 2014

Insights into the structure, correlated motions, and electrostatic properties of two HIV-1 gp120 V3 loops

artículo científico publicado en 2012

Integrated Computational and Experimental Approach for Lead Optimization and Design of Compstatin Variants with Improved Activity

article

M13 bacteriophage spheroids as scaffolds for directed synthesis of spiky gold nanostructures

artículo científico publicado en 2018

Molecular analysis of the interaction between staphylococcal virulence factor Sbi-IV and complement C3d.

artículo científico publicado en 2014

Molecular dynamics in drug design: new generations of compstatin analogs.

artículo científico publicado en 2012

Molecular thermodynamics for charged biomacromolecules

NMR evidence for multiple conformations in a highly helical model peptide.

artículo científico publicado en 1993

NMR evidence of charge-dependent interaction between various PND V3 and CCR5 N-terminal peptides

scientific article published on 01 January 2009

New compstatin peptides containing N-terminal extensions and non-natural amino acids exhibit potent complement inhibition and improved solubility characteristics

artículo científico publicado en 2014

Novel compstatin family peptides inhibit complement activation by drusen-like deposits in human retinal pigmented epithelial cell cultures.

artículo científico publicado en 2013

Physical methods for structure, dynamics and binding in immunological research.

artículo científico publicado en 2004

Related protein-protein interaction modules present drastically different surface topographies despite a conserved helical platform

artículo científico publicado en 2003

Resonance raman investigations of site-directed mutants of myoglobin: effects of distal histidine replacement

artículo científico publicado en 1989

Solution structure of a bent alpha-helix

artículo científico publicado en 2007

Solvation effects in calculated electrostatic association free energies for the C3d-CR2 complex and comparison with experimental data

artículo científico publicado en 2010

Species specificity of the complement inhibitor compstatin investigated by all-atom molecular dynamics simulations

artículo científico publicado en 2010

Spectroscopic studies of myoglobin at low pH: heme structure and ligation

artículo científico publicado en 1991

Structural aspects and design of low-molecular-mass complement inhibitors

artículo científico publicado en 2002

The effect of electrostatics on factor H function and related pathologies

artículo científico publicado en 2011

The molecular basis for protein kinase A anchoring revealed by solution NMR

artículo científico publicado en 1999

The pH dependence of stability of the activation helix and the catalytic site of GART.

artículo científico publicado en 2003

The structural basis of compstatin activity examined by structure-function-based design of peptide analogs and NMR.

artículo científico publicado en 2002

The two sides of complement C3d: evolution of electrostatics in a link between innate and adaptive immunity

artículo científico publicado en 2012

Thermodynamic studies on the interaction of the third complement component and its inhibitor, compstatin

artículo científico publicado en 2004

Two SCA (stigma/style cysteine-rich adhesin) isoforms show structural differences that correlate with their levels of in vitro pollen tube adhesion activity

artículo científico publicado en 2007

Viral regulators of complement activation: structure, function and evolution

artículo científico publicado en 2014

pH dependence of stability of the 10th human fibronectin type III domain: a computational study

artículo científico publicado en 2007

Lista de obras de Dimitrios Morikis

1H resonance assignments and secondary structure of the carbon monoxide complex of soybean leghemoglobin determined by homonuclear two-dimensional and three-dimensional NMR spectroscopy

A New Generation of Potent Complement Inhibitors of the Compstatin Family ⬇️

A computational model for the evaluation of complement system regulation under homeostasis, disease, and drug intervention.

A gain-of-function mutation of Arabidopsis lipid transfer protein 5 disturbs pollen tube tip growth and fertilization

A multifaceted study of stigma/style cysteine-rich adhesin (SCA)-like Arabidopsis lipid transfer proteins (LTPs) suggests diversified roles for these LTPs in plant growth and reproduction

A novel mechanism of PKA anchoring revealed by solution structures of anchoring complexes

A predictive model for HIV type 1 coreceptor selectivity

A theoretical view of the C3d:CR2 binding controversy.

Alteration of sperm whale myoglobin heme axial ligation by site-directed mutagenesis

An evaluation of Poisson-Boltzmann electrostatic free energy calculations through comparison with experimental mutagenesis data.

Automated computational framework for the analysis of electrostatic similarities of proteins

Clustering of HIV-1 Subtypes Based on gp120 V3 Loop electrostatic properties ⬇️

Complement: structure, functions, evolution, and viral molecular mimicry

Compstatin, a peptide inhibitor of complement, exhibits species-specific binding to complement component C3.

Computational studies of CXCR1, the receptor of IL-8/CXCL8, using molecular dynamics and electrostatics

Conformational analysis of compstatin analogues with molecular dynamics simulations in explicit water

Conformational interconversion in compstatin probed with molecular dynamics simulations

Conformational interconversion in protein crystals

Contribution of specific amino acid changes in penicillin binding protein 1 to amoxicillin resistance in clinical Helicobacter pylori isolates

De novo peptide design with C3a receptor agonist and antagonist activities: theoretical predictions and experimental validation

Derivation of ligands for the complement C3a receptor from the C-terminus of C5a

Design and NMR characterization of active analogues of compstatin containing non-natural amino acids

Design of a modified mouse protein with ligand binding properties of its human analog by molecular dynamics simulations: the case of C3 inhibition by compstatin

Development of a quasi-dynamic pharmacophore model for anti-complement peptide analogues

Electrostatic Similarity Determination Using Multiresolution Analysis

Electrostatic clustering and free energy calculations provide a foundation for protein design and optimization.

Electrostatic exploration of the C3d-FH4 interaction using a computational alanine scan

Electrostatic properties of the structure of the docking and dimerization domain of protein kinase A IIalpha

Engineering pre-SUMO4 as efficient substrate of SENP2.

Factor H-Inspired Design of Peptide Biomarkers of the Complement C3d Protein

Hydration of the partially folded peptide RN-24 studied by multidimensional NMR.

Immunophysical exploration of C3d-CR2(CCP1-2) interaction using molecular dynamics and electrostatics

Influence of electrostatics on the complement regulatory functions of Kaposica, the complement inhibitor of Kaposi's sarcoma-associated herpesvirus

Insights into the mechanism of C5aR inhibition by PMX53 via implicit solvent molecular dynamics simulations and docking

Insights into the structure, correlated motions, and electrostatic properties of two HIV-1 gp120 V3 loops

Integrated Computational and Experimental Approach for Lead Optimization and Design of Compstatin Variants with Improved Activity

M13 bacteriophage spheroids as scaffolds for directed synthesis of spiky gold nanostructures

Molecular analysis of the interaction between staphylococcal virulence factor Sbi-IV and complement C3d.

Molecular dynamics in drug design: new generations of compstatin analogs.

Molecular thermodynamics for charged biomacromolecules

NMR evidence for multiple conformations in a highly helical model peptide.

NMR evidence of charge-dependent interaction between various PND V3 and CCR5 N-terminal peptides

New compstatin peptides containing N-terminal extensions and non-natural amino acids exhibit potent complement inhibition and improved solubility characteristics

Novel compstatin family peptides inhibit complement activation by drusen-like deposits in human retinal pigmented epithelial cell cultures.

Physical methods for structure, dynamics and binding in immunological research.

Related protein-protein interaction modules present drastically different surface topographies despite a conserved helical platform

Resonance raman investigations of site-directed mutants of myoglobin: effects of distal histidine replacement

Solution structure of a bent alpha-helix

Solvation effects in calculated electrostatic association free energies for the C3d-CR2 complex and comparison with experimental data

Species specificity of the complement inhibitor compstatin investigated by all-atom molecular dynamics simulations

Spectroscopic studies of myoglobin at low pH: heme structure and ligation

Structural aspects and design of low-molecular-mass complement inhibitors

The effect of electrostatics on factor H function and related pathologies

The molecular basis for protein kinase A anchoring revealed by solution NMR

The pH dependence of stability of the activation helix and the catalytic site of GART.

The structural basis of compstatin activity examined by structure-function-based design of peptide analogs and NMR.

The two sides of complement C3d: evolution of electrostatics in a link between innate and adaptive immunity

Thermodynamic studies on the interaction of the third complement component and its inhibitor, compstatin

Two SCA (stigma/style cysteine-rich adhesin) isoforms show structural differences that correlate with their levels of in vitro pollen tube adhesion activity

Viral regulators of complement activation: structure, function and evolution

pH dependence of stability of the 10th human fibronectin type III domain: a computational study