Lista de obras - Mauro Sola-Penna - Dominio Público Uruguay

A Novel Naphthotriazolyl-4-oxoquinoline Derivative that Selectively Controls Breast Cancer Cells Survival Through the Induction of Apoptosis

artículo científico publicado en 2018

A Novel Triazole Derivative Drug Presenting In Vitro and In Vivo Anticancer Properties

artículo científico publicado en 2018

A new class of mechanism-based inhibitors for Trypanosoma cruzi trans-sialidase and their influence on parasite virulence.

artículo científico publicado en 2010

A radioassay for phosphofructokinase-1 activity in cell extracts and purified enzyme

artículo científico publicado en 2002

Acetylsalicylic acid and salicylic acid decrease tumor cell viability and glucose metabolism modulating 6-phosphofructo-1-kinase structure and activity

artículo científico publicado en 2008

Acetylsalicylic acid and salicylic acid present anticancer properties against melanoma by promoting nitric oxide-dependent endoplasmic reticulum stress and apoptosis

artículo científico publicado en 2020

Amylin induces hypoglycemia in mice

artículo científico publicado en 2013

Antidiabetic activity of Sedum dendroideum: metabolic enzymes as putative targets for the bioactive flavonoid kaempferitrin

artículo científico publicado en 2014

Betaine protects urea-induced denaturation of myosin subfragment-1.

artículo científico publicado en 2008

Biosynthesis of O-N-acetylglucosamine-linked glycans in Trypanosoma cruzi. Characterization of the novel uridine diphospho-N-acetylglucosamine:polypeptide N-acetylglucosaminyltransferase-catalyzing formation of N-acetylglucosamine alpha1-->O-threoni

artículo científico publicado en 1998

Calcium influx: a possible role for insulin modulation of intracellular distribution and activity of 6-phosphofructo-1-kinase in human erythrocytes.

artículo científico publicado en 2005

Calmodulin upregulates skeletal muscle 6-phosphofructo-1-kinase reversing the inhibitory effects of allosteric modulators

artículo científico publicado en 2009

Carbohydrate protection of enzyme structure and function against guanidinium chloride treatment depends on the nature of carbohydrate and enzyme

scientific article published on 01 August 1997

Cellular distribution of phosphofructokinase activity and implications to metabolic regulation in human breast cancer.

artículo científico publicado en 2003

Clotrimazole decreases human breast cancer cells viability through alterations in cytoskeleton-associated glycolytic enzymes

artículo científico publicado en 2005

Clotrimazole disrupts glycolysis in human breast cancer without affecting non-tumoral tissues

artículo científico publicado en 2011

Clotrimazole inhibits and modulates heterologous association of the key glycolytic enzyme 6-phosphofructo-1-kinase

scientific article published on 14 January 2007

Clotrimazole is effective for the regression of endometriotic implants in a Wistar rat experimental model of endometriosis

artículo científico publicado en 2018

Clotrimazole potentiates the inhibitory effects of ATP on the key glycolytic enzyme 6-phosphofructo-1-kinase

artículo científico publicado en 2010

Clotrimazole preferentially inhibits human breast cancer cell proliferation, viability and glycolysis

artículo científico publicado en 2012

Counteracting effects of urea and methylamines in function and structure of skeletal muscle myosin.

artículo científico publicado en 2002

Design, Synthesis and Biological Evaluation of 1H-1,2,3-Triazole-Linked-1H-Dibenzo[b,h]xanthenes as Inductors of ROS-Mediated Apoptosis in the Breast Cancer Cell Line MCF-7

artículo científico publicado en 2019

Discrete Fourier Transform-Based Multivariate Image Analysis: Application to Modeling of Aromatase Inhibitory Activity

artículo científico publicado en 2018

Effects of Food Additives on Immune Cells As Contributors to Body Weight Gain and Immune-Mediated Metabolic Dysregulation

artículo científico publicado en 2017

Epinephrine modulates cellular distribution of muscle phosphofructokinase.

artículo científico publicado en 2003

Epithelial Mesenchymal Transition Induces Aberrant Glycosylation through Hexosamine Biosynthetic Pathway Activation

artículo científico publicado en 2016

Exogenous citrate impairs glucose tolerance and promotes visceral adipose tissue inflammation in mice

artículo científico publicado en 2016

Filamentous actin and its associated binding proteins are the stimulatory site for 6-phosphofructo-1-kinase association within the membrane of human erythrocytes.

artículo científico publicado en 2010

Glucuronoxylomannan from Cryptococcus neoformans down-regulates the enzyme 6-phosphofructo-1-kinase of macrophages.

artículo científico publicado en 2011

Herpes simplex type 1 activates glycolysis through engagement of the enzyme 6-phosphofructo-1-kinase (PFK-1).

artículo científico publicado en 2012

Hexokinase and phosphofructokinase activity and intracellular distribution correlate with aggressiveness and invasiveness of human breast carcinoma.

artículo científico publicado en 2015

Identification of chicoric acid as a hypoglycemic agent from Ocimum gratissimum leaf extract in a biomonitoring in vivo study

artículo científico publicado en 2014

Inhibition of yeast glutathione reductase by trehalose: possible implications in yeast survival and recovery from stress.

artículo científico publicado en 2004

Insulin specifically regulates expression of liver and muscle phosphofructokinase isoforms

artículo científico publicado en 2018

Lactate downregulates the glycolytic enzymes hexokinase and phosphofructokinase in diverse tissues from mice

artículo científico publicado en 2010

Lactate favours the dissociation of skeletal muscle 6-phosphofructo-1-kinase tetramers down-regulating the enzyme and muscle glycolysis

artículo científico publicado en 2007

Mayaro virus infection alters glucose metabolism in cultured cells through activation of the enzyme 6-phosphofructo 1-kinase

artículo científico publicado en 2004

Metabolic regulation by lactate.

artículo científico publicado en 2008

Metformin reverses hexokinase and phosphofructokinase downregulation and intracellular distribution in the heart of diabetic mice

scientific article published on 23 June 2012

Microcapsules of alginate/chitosan containing magnetic nanoparticles for controlled release of insulin.

artículo científico publicado en 2010

Modulation of 6-phosphofructo-1-kinase oligomeric equilibrium by calmodulin: formation of active dimers

scientific article published on 22 December 2005

Monosaccharides and Disaccharides Decrease the K m for Phosphorylation of a Membrane-Bound Enzyme ATPase ⬇️

artículo científico publicado el 1 de julio de 1991

Muscle-type 6-phosphofructo-1-kinase and aldolase associate conferring catalytic advantages for both enzymes.

artículo científico publicado en 2011

Nanomicellar Formulation of Clotrimazole Improves Its Antitumor Action toward Human Breast Cancer Cells

artículo científico publicado en 2015

Ocimum basilicum but not Ocimum gratissimum present cytotoxic effects on human breast cancer cell line MCF-7, inducing apoptosis and triggering mTOR/Akt/p70S6K pathway.

artículo científico publicado en 2018

Opposing effects of two osmolytes--trehalose and glycerol--on thermal inactivation of rabbit muscle 6-phosphofructo-1-kinase.

artículo científico publicado en 2005

Phosphatidylinositol-3-kinase as a putative target for anticancer action of clotrimazole

artículo científico publicado en 2015

Phosphofructokinase-P Modulates P44/42 MAPK Levels in HeLa Cells

artículo científico publicado en 2016

Polymeric particles for the controlled release of human amylin

artículo científico publicado en 2012

Preclinical efficacy of the novel competitive NAMPT inhibitor STF-118804 in pancreatic cancer

artículo científico publicado en 2017

Protection against thermal denaturation by trehalose on the plasma membrane H+-ATPase from yeast. Synergetic effect between trehalose and phospholipid environment

artículo científico publicado en 1999

Proteomic analysis of the secretions of Pseudallescheria boydii, a human fungal pathogen with unknown genome

artículo científico publicado en 2011

Reference genes for quantitative PCR in the adipose tissue of mice with metabolic disease.

artículo científico publicado en 2017

Regulation of human erythrocyte metabolism by insulin: cellular distribution of 6-phosphofructo-1-kinase and its implication for red blood cell function.

artículo científico publicado en 2005

Regulation of mammalian muscle type 6-phosphofructo-1-kinase and its implication for the control of the metabolism

artículo científico publicado en 2010

Resveratrol decreases breast cancer cell viability and glucose metabolism by inhibiting 6-phosphofructo-1-kinase.

artículo científico publicado en 2013

Rhodnius prolixus lipophorin: lipid composition and effect of high temperature on physiological role.

artículo científico publicado en 2013

SIRT1-Activating Compounds (STAC) Negatively Regulate Pancreatic Cancer Cell Growth and Viability Through a SIRT1 Lysosomal-Dependent Pathway

artículo científico publicado en 2015

Serotonin activates glycolysis and mitochondria biogenesis in human breast cancer cells through activation of the Jak1/STAT3/ERK1/2 and adenylate cyclase/PKA, respectively

scientific article published on 10 December 2019

Serotonin modulates hepatic 6-phosphofructo-1-kinase in an insulin synergistic manner.

artículo científico publicado en 2011

Serotonin regulates 6-phosphofructo-1-kinase activity in a PLC–PKC–CaMK II- and Janus kinase-dependent signaling pathway ⬇️

artículo científico publicado el 26 de septiembre de 2012

Serotonin regulates an acyl-CoA-binding protein (ACBP) gene expression in the midgut of Rhodnius prolixus.

artículo científico publicado en 2010

Serotonin stimulates mouse skeletal muscle 6-phosphofructo-1-kinase through tyrosine-phosphorylation of the enzyme altering its intracellular localization

scientific journal article

Stabilization against thermal inactivation promoted by sugars on enzyme structure and function: why is trehalose more effective than other sugars?

artículo científico publicado en 1998

Subversion of Schwann Cell Glucose Metabolism by Mycobacterium leprae

artículo científico publicado en 2016

Subversion of Schwann cell glucose metabolism by Mycobacterium leprae

artículo científico publicado en 2016

The Use of NMR Metabolite Profiling and in vivo Hypoglycemic Assay for Comparison of Unfractionated Aqueous Leaf Extracts of Two Ocimum Species

artículo científico publicado en 2016

Therapeutic nanosystems for oral administration of insulin.

artículo científico

Trehalose and glycerol stabilize and renature yeast inorganic pyrophosphatase inactivated by very high temperatures.

artículo científico publicado en 2005

Unique PFK regulatory property from some mosquito vectors of disease, and from Drosophila melanogaster

artículo científico publicado en 2016

Urea increases tolerance of yeast inorganic pyrophosphatase activity to ethanol: the other side of urea interaction with proteins.

artículo científico publicado en 2001

p-Nitrophenylphosphatase activity catalyzed by plasma membrane (Ca(2+) + Mg(2+)ATPase: correlation with structural changes modulated by glycerol and Ca(2+).

artículo científico publicado en 2001

Lista de obras de Mauro Sola-Penna

A Novel Naphthotriazolyl-4-oxoquinoline Derivative that Selectively Controls Breast Cancer Cells Survival Through the Induction of Apoptosis

A Novel Triazole Derivative Drug Presenting In Vitro and In Vivo Anticancer Properties

A new class of mechanism-based inhibitors for Trypanosoma cruzi trans-sialidase and their influence on parasite virulence.

A radioassay for phosphofructokinase-1 activity in cell extracts and purified enzyme

Acetylsalicylic acid and salicylic acid decrease tumor cell viability and glucose metabolism modulating 6-phosphofructo-1-kinase structure and activity

Acetylsalicylic acid and salicylic acid present anticancer properties against melanoma by promoting nitric oxide-dependent endoplasmic reticulum stress and apoptosis

Amylin induces hypoglycemia in mice

Antidiabetic activity of Sedum dendroideum: metabolic enzymes as putative targets for the bioactive flavonoid kaempferitrin

Betaine protects urea-induced denaturation of myosin subfragment-1.

Biosynthesis of O-N-acetylglucosamine-linked glycans in Trypanosoma cruzi. Characterization of the novel uridine diphospho-N-acetylglucosamine:polypeptide N-acetylglucosaminyltransferase-catalyzing formation of N-acetylglucosamine alpha1-->O-threoni

Calcium influx: a possible role for insulin modulation of intracellular distribution and activity of 6-phosphofructo-1-kinase in human erythrocytes.

Calmodulin upregulates skeletal muscle 6-phosphofructo-1-kinase reversing the inhibitory effects of allosteric modulators

Carbohydrate protection of enzyme structure and function against guanidinium chloride treatment depends on the nature of carbohydrate and enzyme

Cellular distribution of phosphofructokinase activity and implications to metabolic regulation in human breast cancer.

Clotrimazole decreases human breast cancer cells viability through alterations in cytoskeleton-associated glycolytic enzymes

Clotrimazole disrupts glycolysis in human breast cancer without affecting non-tumoral tissues

Clotrimazole inhibits and modulates heterologous association of the key glycolytic enzyme 6-phosphofructo-1-kinase

Clotrimazole is effective for the regression of endometriotic implants in a Wistar rat experimental model of endometriosis

Clotrimazole potentiates the inhibitory effects of ATP on the key glycolytic enzyme 6-phosphofructo-1-kinase

Clotrimazole preferentially inhibits human breast cancer cell proliferation, viability and glycolysis

Counteracting effects of urea and methylamines in function and structure of skeletal muscle myosin.

Design, Synthesis and Biological Evaluation of 1H-1,2,3-Triazole-Linked-1H-Dibenzo[b,h]xanthenes as Inductors of ROS-Mediated Apoptosis in the Breast Cancer Cell Line MCF-7

Discrete Fourier Transform-Based Multivariate Image Analysis: Application to Modeling of Aromatase Inhibitory Activity

Effects of Food Additives on Immune Cells As Contributors to Body Weight Gain and Immune-Mediated Metabolic Dysregulation

Epinephrine modulates cellular distribution of muscle phosphofructokinase.

Epithelial Mesenchymal Transition Induces Aberrant Glycosylation through Hexosamine Biosynthetic Pathway Activation

Exogenous citrate impairs glucose tolerance and promotes visceral adipose tissue inflammation in mice

Filamentous actin and its associated binding proteins are the stimulatory site for 6-phosphofructo-1-kinase association within the membrane of human erythrocytes.

Glucuronoxylomannan from Cryptococcus neoformans down-regulates the enzyme 6-phosphofructo-1-kinase of macrophages.

Herpes simplex type 1 activates glycolysis through engagement of the enzyme 6-phosphofructo-1-kinase (PFK-1).

Hexokinase and phosphofructokinase activity and intracellular distribution correlate with aggressiveness and invasiveness of human breast carcinoma.

Identification of chicoric acid as a hypoglycemic agent from Ocimum gratissimum leaf extract in a biomonitoring in vivo study

Inhibition of yeast glutathione reductase by trehalose: possible implications in yeast survival and recovery from stress.

Insulin specifically regulates expression of liver and muscle phosphofructokinase isoforms

Lactate downregulates the glycolytic enzymes hexokinase and phosphofructokinase in diverse tissues from mice

Lactate favours the dissociation of skeletal muscle 6-phosphofructo-1-kinase tetramers down-regulating the enzyme and muscle glycolysis

Mayaro virus infection alters glucose metabolism in cultured cells through activation of the enzyme 6-phosphofructo 1-kinase

Metabolic regulation by lactate.

Metformin reverses hexokinase and phosphofructokinase downregulation and intracellular distribution in the heart of diabetic mice

Microcapsules of alginate/chitosan containing magnetic nanoparticles for controlled release of insulin.

Modulation of 6-phosphofructo-1-kinase oligomeric equilibrium by calmodulin: formation of active dimers

Monosaccharides and Disaccharides Decrease the K m for Phosphorylation of a Membrane-Bound Enzyme ATPase ⬇️

Muscle-type 6-phosphofructo-1-kinase and aldolase associate conferring catalytic advantages for both enzymes.

Nanomicellar Formulation of Clotrimazole Improves Its Antitumor Action toward Human Breast Cancer Cells

Ocimum basilicum but not Ocimum gratissimum present cytotoxic effects on human breast cancer cell line MCF-7, inducing apoptosis and triggering mTOR/Akt/p70S6K pathway.

Opposing effects of two osmolytes--trehalose and glycerol--on thermal inactivation of rabbit muscle 6-phosphofructo-1-kinase.

Phosphatidylinositol-3-kinase as a putative target for anticancer action of clotrimazole

Phosphofructokinase-P Modulates P44/42 MAPK Levels in HeLa Cells

Polymeric particles for the controlled release of human amylin

Preclinical efficacy of the novel competitive NAMPT inhibitor STF-118804 in pancreatic cancer

Protection against thermal denaturation by trehalose on the plasma membrane H+-ATPase from yeast. Synergetic effect between trehalose and phospholipid environment

Proteomic analysis of the secretions of Pseudallescheria boydii, a human fungal pathogen with unknown genome

Reference genes for quantitative PCR in the adipose tissue of mice with metabolic disease.

Regulation of human erythrocyte metabolism by insulin: cellular distribution of 6-phosphofructo-1-kinase and its implication for red blood cell function.

Regulation of mammalian muscle type 6-phosphofructo-1-kinase and its implication for the control of the metabolism

Resveratrol decreases breast cancer cell viability and glucose metabolism by inhibiting 6-phosphofructo-1-kinase.

Rhodnius prolixus lipophorin: lipid composition and effect of high temperature on physiological role.

SIRT1-Activating Compounds (STAC) Negatively Regulate Pancreatic Cancer Cell Growth and Viability Through a SIRT1 Lysosomal-Dependent Pathway

Serotonin activates glycolysis and mitochondria biogenesis in human breast cancer cells through activation of the Jak1/STAT3/ERK1/2 and adenylate cyclase/PKA, respectively

Serotonin modulates hepatic 6-phosphofructo-1-kinase in an insulin synergistic manner.

Serotonin regulates 6-phosphofructo-1-kinase activity in a PLC–PKC–CaMK II- and Janus kinase-dependent signaling pathway ⬇️

Serotonin regulates an acyl-CoA-binding protein (ACBP) gene expression in the midgut of Rhodnius prolixus.

Serotonin stimulates mouse skeletal muscle 6-phosphofructo-1-kinase through tyrosine-phosphorylation of the enzyme altering its intracellular localization

Stabilization against thermal inactivation promoted by sugars on enzyme structure and function: why is trehalose more effective than other sugars?

Subversion of Schwann Cell Glucose Metabolism by Mycobacterium leprae

Subversion of Schwann cell glucose metabolism by Mycobacterium leprae

The Use of NMR Metabolite Profiling and in vivo Hypoglycemic Assay for Comparison of Unfractionated Aqueous Leaf Extracts of Two Ocimum Species

Therapeutic nanosystems for oral administration of insulin.

Trehalose and glycerol stabilize and renature yeast inorganic pyrophosphatase inactivated by very high temperatures.

Unique PFK regulatory property from some mosquito vectors of disease, and from Drosophila melanogaster

Urea increases tolerance of yeast inorganic pyrophosphatase activity to ethanol: the other side of urea interaction with proteins.

p-Nitrophenylphosphatase activity catalyzed by plasma membrane (Ca(2+) + Mg(2+)ATPase: correlation with structural changes modulated by glycerol and Ca(2+).