Lista de obras - Kevin M Ryan - Dominio Público Uruguay

A p53-derived apoptotic peptide derepresses p73 to cause tumor regression in vivo.

artículo científico publicado en 2007

Activation of p73 and induction of Noxa by DNA damage requires NF-kappa B.

artículo científico publicado en 2009

Analysis of DRAM-related proteins reveals evolutionarily conserved and divergent roles in the control of autophagy

artículo científico publicado en 2009

Analysis of E-box DNA binding during myeloid differentiation reveals complexes that contain Mad but not Max.

artículo científico

Analysis of macroautophagy by immunohistochemistry

artículo científico publicado en 2012

Androgens modulate autophagy and cell death via regulation of the endoplasmic reticulum chaperone glucose-regulated protein 78/BiP in prostate cancer cells

artículo científico publicado en 2010

Autophagy and cancer

artículo científico

Autophagy and cancer--issues we need to digest

artículo científico publicado en 2012

Autophagy chews Fap to promote apoptosis

artículo científico publicado en 2014

Autophagy in malignant transformation and cancer progression

artículo científico publicado en 2015

Autophagy in tumour cell death

artículo científico

Autophagy, Inflammation, and Metabolism (AIM) Center of Biomedical Research Excellence: supporting the next generation of autophagy researchers and fostering international collaborations

artículo científico publicado en 2018

Autophagy, the innate immune response and cancer

artículo científico publicado en 2020

Autophagy: an adaptable modifier of tumourigenesis

artículo científico publicado en 2010

Cancer: Viruses' backup plan

artículo científico publicado en 2010

Cell cycle arrest and DNA endoreduplication following p21Waf1/Cip1 expression

artículo científico publicado en 1998

Cell-cycle progression is not essential for c-Myc to block differentiation

artículo científico publicado en 1997

Characterization of structural p53 mutants which show selective defects in apoptosis but not cell cycle arrest

artículo científico publicado en 1998

DNA-binding independent cell death from a minimal proapoptotic region of E2F-1.

artículo científico

DRAM links autophagy to p53 and programmed cell death

artículo científico publicado en 2007

DRAM, a p53-induced modulator of autophagy, is critical for apoptosis

artículo científico publicado en 2006

DRAM-1 encodes multiple isoforms that regulate autophagy

artículo científico publicado en 2012

DRAM-3 modulates autophagy and promotes cell survival in the absence of glucose

artículo científico publicado en 2015

Differentiating embryonal stem cells are a rich source of haemopoietic gene products and suggest erythroid preconditioning of primitive haemopoietic stem cells

scientific journal article

Does androgen-ablation therapy (AAT) associated autophagy have a pro-survival effect in LNCaP human prostate cancer cells?

artículo científico publicado en 2012

E2F1 drives chemotherapeutic drug resistance via ABCG2.

artículo científico publicado en 2013

Emerging roles of transcriptional programs in autophagy regulation

artículo científico publicado en 2017

Evidence for the interplay between JNK and p53-DRAM signalling pathways in the regulation of autophagy

artículo científico publicado en 2010

Extracellular adenosine sensing-a metabolic cell death priming mechanism downstream of p53.

artículo científico publicado en 2013

Glucose-starved cells do not engage in prosurvival autophagy

artículo científico publicado en 2013

Growth factor signaling permits hypoxia-induced autophagy by a HIF1α-dependent, BNIP3/3L-independent transcriptional program in human cancer cells

artículo científico publicado en 2009

Guidelines for the use and interpretation of assays for monitoring autophagy

artículo científico publicado en 2012

Guidelines for the use and interpretation of assays for monitoring autophagy in higher eukaryotes

artículo científico publicado en 2008

Hemizygosity of the MAX Gene Locus in HL60 Cells

article

Hypoxia-selective macroautophagy and cell survival signaled by autocrine PDGFR activity

artículo científico publicado en 2009

Hzf and hCAS/CSE1L: making the right choice in p53-mediated tumour suppression

scientific article published on 01 October 2007

Immunohistochemical detection of cytoplasmic LC3 puncta in human cancer specimens

scientific article published on 31 May 2012

Induction of DNA synthesis and apoptosis are separable functions of E2F-1.

artículo científico publicado en 1997

Inhibition of HIF-1- and wild-type p53-stimulated transcription by codon Arg175 p53 mutants with selective loss of functions

artículo científico publicado en 2001

Inhibition of autophagy impairs tumor cell invasion in an organotypic model

artículo científico publicado en 2012

Involvement of RNA Polymerase III in Immune Responses.

artículo científico publicado en 2015

Life and death decisions by E2F-1.

artículo científico publicado en 2004

Loss of autophagy causes a synthetic lethal deficiency in DNA repair.

artículo científico publicado en 2015

Loss of nuclear factor-kappaB is tumor promoting but does not substitute for loss of p53.

artículo científico publicado en 2004

Lysosomal proteins in cell death and autophagy

artículo científico publicado en 2015

MDM2 promotes SUMO-2/3 modification of p53 to modulate transcriptional activity

scientific journal article

Mechanistic and predictive profiling of 5-Fluorouracil resistance in human cancer cells.

artículo científico publicado en 2004

Molecular definitions of autophagy and related processes.

artículo científico publicado en 2017

Molecular mechanisms of cell death: recommendations of the Nomenclature Committee on Cell Death 2018.

artículo científico publicado en 2018

Myc oncogenes: the enigmatic family

artículo científico publicado en 1996

New frontiers in promoting tumour cell death: targeting apoptosis, necroptosis and autophagy

artículo científico

Oncogene-induced sensitization to chemotherapy-induced death requires induction as well as deregulation of E2F1.

artículo científico publicado en 2010

PUMA- and Bax-induced autophagy contributes to apoptosis

artículo científico publicado en 2009

Phosphorylation of Puma modulates its apoptotic function by regulating protein stability

artículo científico publicado en 2010

Pinning a change on p53

scientific article published in Nature

Regulation and function of the p53 tumor suppressor protein

artículo científico publicado en 2001

Retrograde signaling from autophagy modulates stress responses.

artículo científico publicado en 2017

Role of NF-κB in p53-mediated programmed cell death

artículo científico publicado en 2000

Role of autophagy in cancer prevention, development and therapy

artículo científico publicado en 2013

Senescence sensitivity of breast cancer cells is defined by positive feedback loop between CIP2A and E2F1.

artículo científico publicado en 2013

Splicing DNA-damage responses to tumour cell death.

artículo científico publicado en 2004

TSC-22D1 isoforms have opposing roles in mammary epithelial cell survival

scientific journal article

Targeting the p53 family for cancer therapy: 'big brother' joins the fight.

artículo científico publicado en 2007

The alternative product from the human CDKN2A locus, p14(ARF), participates in a regulatory feedback loop with p53 and MDM2.

artículo científico publicado en 1998

The cyclin-dependent kinase PITSLRE/CDK11 is required for successful autophagy

artículo científico publicado en 2011

The multiple roles of autophagy in cancer

artículo científico publicado en 2011

The role of autophagy in tumour development and cancer therapy.

artículo científico publicado en 2009

Transcriptional regulation of autophagy and lysosomal function by bromodomain protein BRD4.

artículo científico publicado en 2017

Tumor antigen LRRC15 impedes adenoviral infection: implications for virus-based cancer therapy

artículo científico publicado en 2008

Tumor regression following intravenous administration of a tumor-targeted p73 gene delivery system

artículo científico publicado en 2011

Ubiquitination and proteasomal degradation of ATG12 regulates its proapoptotic activity

artículo científico publicado en 2014

Using enhanced-mitophagy to measure autophagic flux.

artículo científico publicado en 2014

c-Jun NH2-terminal kinase activation is essential for DRAM-dependent induction of autophagy and apoptosis in 2-methoxyestradiol-treated Ewing sarcoma cells

artículo científico publicado en 2009

iASPP inhibition: increased options in targeting the p53 family for cancer therapy.

artículo científico publicado en 2008

p53 activates ICAM-1 (CD54) expression in an NF-kappaB-independent manner

artículo científico publicado en 2003

p53 and autophagy in cancer: Guardian of the genome meets guardian of the proteome ⬇️

artículo científico publicado el 25 de noviembre de 2010

p53 and metabolism

artículo científico publicado en 2009

p53 and senescence: A little goes a long way

articulo cientifico

p53 and senescence: a little goes a long way.

artículo científico publicado en 2010

p53 and tumor surveillance: Killer finds way to recruit assassins

scientific article published on 15 November 2011

p53 status determines the role of autophagy in pancreatic tumour development

artículo científico publicado en 2013

p53-mediated induction of Noxa and p53AIP1 requires NFkappaB.

artículo científico publicado en 2010

p53-mediated transcriptional regulation and activation of the actin cytoskeleton regulatory RhoC to LIMK2 signaling pathway promotes cell survival

artículo científico publicado en 2010

p73 engages A2B receptor signalling to prime cancer cells to chemotherapy-induced death

artículo científico

p73 regulates DRAM-independent autophagy that does not contribute to programmed cell death

artículo científico publicado en 2007

Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition)

artículo científico publicado en 2016

Lista de obras de Kevin M Ryan

A p53-derived apoptotic peptide derepresses p73 to cause tumor regression in vivo.

Activation of p73 and induction of Noxa by DNA damage requires NF-kappa B.

Analysis of DRAM-related proteins reveals evolutionarily conserved and divergent roles in the control of autophagy

Analysis of E-box DNA binding during myeloid differentiation reveals complexes that contain Mad but not Max.

Analysis of macroautophagy by immunohistochemistry

Androgens modulate autophagy and cell death via regulation of the endoplasmic reticulum chaperone glucose-regulated protein 78/BiP in prostate cancer cells

Autophagy and cancer

Autophagy and cancer--issues we need to digest

Autophagy chews Fap to promote apoptosis

Autophagy in malignant transformation and cancer progression

Autophagy in tumour cell death

Autophagy, Inflammation, and Metabolism (AIM) Center of Biomedical Research Excellence: supporting the next generation of autophagy researchers and fostering international collaborations

Autophagy, the innate immune response and cancer

Autophagy: an adaptable modifier of tumourigenesis

Cancer: Viruses' backup plan

Cell cycle arrest and DNA endoreduplication following p21Waf1/Cip1 expression

Cell-cycle progression is not essential for c-Myc to block differentiation

Characterization of structural p53 mutants which show selective defects in apoptosis but not cell cycle arrest

DNA-binding independent cell death from a minimal proapoptotic region of E2F-1.

DRAM links autophagy to p53 and programmed cell death

DRAM, a p53-induced modulator of autophagy, is critical for apoptosis

DRAM-1 encodes multiple isoforms that regulate autophagy

DRAM-3 modulates autophagy and promotes cell survival in the absence of glucose

Differentiating embryonal stem cells are a rich source of haemopoietic gene products and suggest erythroid preconditioning of primitive haemopoietic stem cells

Does androgen-ablation therapy (AAT) associated autophagy have a pro-survival effect in LNCaP human prostate cancer cells?

E2F1 drives chemotherapeutic drug resistance via ABCG2.

Emerging roles of transcriptional programs in autophagy regulation

Evidence for the interplay between JNK and p53-DRAM signalling pathways in the regulation of autophagy

Extracellular adenosine sensing-a metabolic cell death priming mechanism downstream of p53.

Glucose-starved cells do not engage in prosurvival autophagy

Growth factor signaling permits hypoxia-induced autophagy by a HIF1α-dependent, BNIP3/3L-independent transcriptional program in human cancer cells

Guidelines for the use and interpretation of assays for monitoring autophagy

Guidelines for the use and interpretation of assays for monitoring autophagy in higher eukaryotes

Hemizygosity of the MAX Gene Locus in HL60 Cells

Hypoxia-selective macroautophagy and cell survival signaled by autocrine PDGFR activity

Hzf and hCAS/CSE1L: making the right choice in p53-mediated tumour suppression

Immunohistochemical detection of cytoplasmic LC3 puncta in human cancer specimens

Induction of DNA synthesis and apoptosis are separable functions of E2F-1.

Inhibition of HIF-1- and wild-type p53-stimulated transcription by codon Arg175 p53 mutants with selective loss of functions

Inhibition of autophagy impairs tumor cell invasion in an organotypic model

Involvement of RNA Polymerase III in Immune Responses.

Life and death decisions by E2F-1.

Loss of autophagy causes a synthetic lethal deficiency in DNA repair.

Loss of nuclear factor-kappaB is tumor promoting but does not substitute for loss of p53.

Lysosomal proteins in cell death and autophagy

MDM2 promotes SUMO-2/3 modification of p53 to modulate transcriptional activity

Mechanistic and predictive profiling of 5-Fluorouracil resistance in human cancer cells.

Molecular definitions of autophagy and related processes.

Molecular mechanisms of cell death: recommendations of the Nomenclature Committee on Cell Death 2018.

Myc oncogenes: the enigmatic family

New frontiers in promoting tumour cell death: targeting apoptosis, necroptosis and autophagy

Oncogene-induced sensitization to chemotherapy-induced death requires induction as well as deregulation of E2F1.

PUMA- and Bax-induced autophagy contributes to apoptosis

Phosphorylation of Puma modulates its apoptotic function by regulating protein stability

Pinning a change on p53

Regulation and function of the p53 tumor suppressor protein

Retrograde signaling from autophagy modulates stress responses.

Role of NF-κB in p53-mediated programmed cell death

Role of autophagy in cancer prevention, development and therapy

Senescence sensitivity of breast cancer cells is defined by positive feedback loop between CIP2A and E2F1.

Splicing DNA-damage responses to tumour cell death.

TSC-22D1 isoforms have opposing roles in mammary epithelial cell survival

Targeting the p53 family for cancer therapy: 'big brother' joins the fight.

The alternative product from the human CDKN2A locus, p14(ARF), participates in a regulatory feedback loop with p53 and MDM2.

The cyclin-dependent kinase PITSLRE/CDK11 is required for successful autophagy

The multiple roles of autophagy in cancer

The role of autophagy in tumour development and cancer therapy.

Transcriptional regulation of autophagy and lysosomal function by bromodomain protein BRD4.

Tumor antigen LRRC15 impedes adenoviral infection: implications for virus-based cancer therapy

Tumor regression following intravenous administration of a tumor-targeted p73 gene delivery system

Ubiquitination and proteasomal degradation of ATG12 regulates its proapoptotic activity

Using enhanced-mitophagy to measure autophagic flux.

c-Jun NH2-terminal kinase activation is essential for DRAM-dependent induction of autophagy and apoptosis in 2-methoxyestradiol-treated Ewing sarcoma cells

iASPP inhibition: increased options in targeting the p53 family for cancer therapy.

p53 activates ICAM-1 (CD54) expression in an NF-kappaB-independent manner

p53 and autophagy in cancer: Guardian of the genome meets guardian of the proteome ⬇️

p53 and metabolism

p53 and senescence: A little goes a long way

p53 and senescence: a little goes a long way.