Lista de obras - Jean Rosenbaum - Dominio Público Uruguay

A novel small-molecule screening strategy identifies mitoxantrone as a RhoGTPase inhibitor.

artículo científico publicado en 2013

A protective role for CD154 in hepatic steatosis in mice ⬇️

artículo científico publicado el 9 de noviembre de 2010

A role for thrombin in liver fibrosis

artículo científico publicado en 2004

Abnormal hepatic expression of fibrillin-1 in children with cholestasis

artículo científico publicado en 2002

Adenosine triphosphatase pontin is overexpressed in hepatocellular carcinoma and coregulated with reptin through a new posttranslational mechanism

artículo científico publicado en 2009

Cellular retinol-binding protein-1 expression and modulation during in vivo and in vitro myofibroblastic differentiation of rat hepatic stellate cells and portal fibroblasts

artículo científico publicado en 2002

Closing the gap on drug-induced liver injury

scientific article published on 01 August 2012

Comparison of IMAC and MOAC for phosphopeptide enrichment by column chromatography

artículo científico publicado en 2012

Cytokines pattern after surgical radiofrequency ablation of liver colorectal metastases

artículo científico publicado en 2007

Decreased toxicity of polymorphonuclear neutrophils toward hepatocytes isolated from rats with acute inflammatory reaction

artículo científico publicado en 1990

Design, synthesis and biological evaluation of Pontin ATPase inhibitors through a molecular docking approach.

artículo científico publicado en 2014

Dietary lecithin protects against cholestatic liver disease in cholic acid-fed Abcb4- deficient mice

artículo científico publicado en 2007

Direct evidence that hepatocyte growth factor-induced invasion of hepatocellular carcinoma cells is mediated by urokinase.

artículo científico publicado en 1999

Discoidin domain receptor 1 controls linear invadosome formation via a Cdc42-Tuba pathway

artículo científico publicado en 2014

Distribution of [14C]-trans-resveratrol, a cancer chemopreventive polyphenol, in mouse tissues after oral administration

artículo científico publicado en 2003

Down-regulation of connective tissue growth factor and type I collagen mRNA expression by connective tissue growth factor antisense oligonucleotide during experimental liver fibrosis

artículo científico publicado en 2004

Editorial: Collaborative Efforts to Prevent Alzheimer's Disease

artículo científico publicado en 2017

Effect of simvastatin, an inhibitor of hydroxy-methylglutaryl coenzyme A reductase, on the growth of human Ito cells

artículo científico publicado en 1994

Effects of bile acids on biliary epithelial cell proliferation and portal fibroblast activation using rat liver slices

artículo científico publicado en 2006

Effects of bile acids on biliary epithelial cells: proliferation, cytotoxicity, and cytokine secretion

artículo científico publicado en 2003

Effects of long-term administration of interferon α in two models of liver fibrosis in rats

artículo científico publicado en 1998

Expression and activity of the cytolethal distending toxin of Helicobacter hepaticus

artículo científico publicado en 2004

Expression and cellular localization of fibrillin-1 in normal and pathological human liver

artículo científico publicado en 2001

Expression and cellular localization of the urokinase-type plasminogen activator and its receptor in human hepatocellular carcinoma

scientific article published on 01 February 2000

Expression of collagens type I and IV, osteonectin and transforming growth factor beta-1 (TGFbeta1) in biliary atresia and paucity of intrahepatic bile ducts during infancy

artículo científico publicado en 1999

Expression of hepatocyte growth factor in human hepatocellular carcinoma

scientific article published on 01 January 2001

Expression of leukemia inhibitory factor (LIF) and its receptor gp190 in human liver and in cultured human liver myofibroblasts. Cloning of new isoforms of LIF mRNA

artículo científico publicado en 2004

Expression of protease-activated receptors and tissue factor in human liver

artículo científico publicado en 2005

Extracellular matrix composition and integrin expression in early hepatocarcinogenesis in human cirrhotic liver

scientific article published on 01 March 1997

Extracellular matrix rigidity controls podosome induction in microvascular endothelial cells.

artículo científico publicado en 2012

Fibroblast growth factor 2 and transforming growth factor beta 1 interactions in human liver myofibroblasts

artículo científico publicado en 1995

First identification of small-molecule inhibitors of Pontin by combining virtual screening and enzymatic assay

artículo científico publicado en 2012

Halofuginone suppresses the lung metastasis of chemically induced hepatocellular carcinoma in rats through MMP inhibition.

artículo científico publicado en 2006

Heparan sulfate proteoglycan expression in chronic cholestatic human liver diseases

scientific article published on 01 September 1996

Hepatic lesions observed in hepatitis C virus transgenic mice infected by Helicobacter hepaticus

artículo científico publicado en 2012

Hepatitis C virus proteins do not directly trigger fibrogenic events in cultured human liver myofibroblasts

artículo científico publicado en 2003

Immunohistochemical detection of hcv in cirrhosis, dysplastic nodules, and hepatocellular carcinomas with parallel-tissue quantitative RT-PCR.

artículo científico publicado en 2001

In vivo MR imaging of intravascularly injected magnetically labeled mesenchymal stem cells in rat kidney and liver.

artículo científico publicado en 2004

In vivo silencing of Reptin blocks the progression of human hepatocellular carcinoma in xenografts and is associated with replicative senescence

artículo científico publicado en 2010

Inhibition of rat liver fibrogenesis through noradrenergic antagonism

artículo científico publicado en 2002

Integrative quantitative proteomics unveils proteostasis imbalance in human hepatocellular carcinoma developed on nonfibrotic livers

artículo científico publicado en 2014

Involvement of matrix metalloproteinase type-3 in hepatocyte growth factor-induced invasion of human hepatocellular carcinoma cells

artículo científico publicado en 2002

Liver Reptin/RUVBL2 controls glucose and lipid metabolism with opposite actions on mTORC1 and mTORC2 signalling

artículo científico publicado en 2017

Liver myofibroblasts activate protein C and respond to activated protein C.

artículo científico publicado en 2010

Matrix metalloproteinase 3 is present in the cell nucleus and is involved in apoptosis.

artículo científico publicado en 2006

Metalloproteinase meprin α regulates migration and invasion of human hepatocarcinoma cells and is a mediator of the oncoprotein Reptin

artículo científico publicado en 2016

Mitogenic effect of transforming growth factor-beta 1 on human Ito cells in culture: evidence for mediation by endogenous platelet-derived growth factor

artículo científico publicado en 1993

Myofibroblasts are responsible for collagen synthesis in the stroma of human hepatocellular carcinoma: an in vivo and in vitro study

artículo científico publicado en 1999

Osteonectin/SPARC is overexpressed in human hepatocellular carcinoma

artículo científico publicado en 1999

Overexpression and role of the ATPase and putative DNA helicase RuvB-like 2 in human hepatocellular carcinoma

artículo científico publicado en 2007

PAV-1, a new rat hepatic stellate cell line converts retinol into retinoic acid, a process altered by ethanol.

artículo científico publicado en 2002

Paradoxical pro-invasive effect of the serine proteinase inhibitor tissue factor pathway inhibitor-2 on human hepatocellular carcinoma cells.

artículo científico publicado en 2000

Pentoxifylline inhibits growth and collagen synthesis of cultured human hepatic myofibroblast-like cells

artículo científico publicado en 1997

Physiological type I collagen organization induces the formation of a novel class of linear invadosomes

artículo científico publicado en 2011

Pontin and reptin, two related ATPases with multiple roles in cancer.

artículo científico publicado en 2008

Posttranscriptional regulation of PER1 underlies the oncogenic function of IREα.

artículo científico publicado en 2013

Protease-activated receptor 1 knockout reduces experimentally induced liver fibrosis

artículo científico publicado en 2007

Proteomic analysis of differentially expressed proteins in hepatocellular carcinoma developed in patients with chronic viral hepatitis C.

artículo científico publicado en 2005

Reptin regulates DNA double strand breaks repair in human hepatocellular carcinoma

artículo científico publicado en 2015

Reptin regulates insulin-stimulated Akt phosphorylation in hepatocellular carcinoma via the regulation of SHP-1/PTPN6.

artículo científico publicado en 2017

Restricted expression of membrane type 1-matrix metalloproteinase by myofibroblasts adjacent to human breast cancer cells

artículo científico publicado en 2003

Rnd3/RhoE Is down-regulated in hepatocellular carcinoma and controls cellular invasion

artículo científico

Sorafenib-mediated targeting of the AAA⁺ ATPase p97/VCP leads to disruption of the secretory pathway, endoplasmic reticulum stress, and hepatocellular cancer cell death

artículo científico publicado en 2012

The ARE-associated factor AUF1 binds poly(A) in vitro in competition with PABP.

artículo científico publicado en 2006

The ATPase activity of reptin is required for its effects on tumor cell growth and viability in hepatocellular carcinoma

artículo científico publicado en 2012

The Oxygen Paradox, the French Paradox, and age-related diseases.

artículo científico publicado en 2017

The emergence of the conserved AAA+ ATPases Pontin and Reptin on the signaling landscape

artículo científico publicado en 2013

The grape-derived polyphenol resveratrol differentially affects epidermal and platelet-derived growth factor signaling in human liver myofibroblasts.

artículo científico publicado en 2005

The multifaceted proteins Reptin and Pontin as major players in cancer

artículo científico publicado en 2010

Thrombin up-regulates tissue factor pathway inhibitor-2 synthesis through a cyclooxygenase-2-dependent, epidermal growth factor receptor-independent mechanism

artículo científico publicado en 2003

Vitamin A-guided siRNAs targeting a collagen chaperone can reverse experimental cirrhosis

artículo científico publicado en 2008

[A little less respite for hepatocellular carcinoma?]

scientific article published on 01 November 2007

[Fundamental and translational research on hepatocellular carcinoma in 2008: forces and priorities]

artículo científico publicado en 2009

[Mechanisms of hepatic fibrogenesis]

artículo científico publicado en 2002

Lista de obras de Jean Rosenbaum

A novel small-molecule screening strategy identifies mitoxantrone as a RhoGTPase inhibitor.

A protective role for CD154 in hepatic steatosis in mice ⬇️

A role for thrombin in liver fibrosis

Abnormal hepatic expression of fibrillin-1 in children with cholestasis

Adenosine triphosphatase pontin is overexpressed in hepatocellular carcinoma and coregulated with reptin through a new posttranslational mechanism

Cellular retinol-binding protein-1 expression and modulation during in vivo and in vitro myofibroblastic differentiation of rat hepatic stellate cells and portal fibroblasts

Closing the gap on drug-induced liver injury

Comparison of IMAC and MOAC for phosphopeptide enrichment by column chromatography

Cytokines pattern after surgical radiofrequency ablation of liver colorectal metastases

Decreased toxicity of polymorphonuclear neutrophils toward hepatocytes isolated from rats with acute inflammatory reaction

Design, synthesis and biological evaluation of Pontin ATPase inhibitors through a molecular docking approach.

Dietary lecithin protects against cholestatic liver disease in cholic acid-fed Abcb4- deficient mice

Direct evidence that hepatocyte growth factor-induced invasion of hepatocellular carcinoma cells is mediated by urokinase.

Discoidin domain receptor 1 controls linear invadosome formation via a Cdc42-Tuba pathway

Distribution of [14C]-trans-resveratrol, a cancer chemopreventive polyphenol, in mouse tissues after oral administration

Down-regulation of connective tissue growth factor and type I collagen mRNA expression by connective tissue growth factor antisense oligonucleotide during experimental liver fibrosis

Editorial: Collaborative Efforts to Prevent Alzheimer's Disease

Effect of simvastatin, an inhibitor of hydroxy-methylglutaryl coenzyme A reductase, on the growth of human Ito cells

Effects of bile acids on biliary epithelial cell proliferation and portal fibroblast activation using rat liver slices

Effects of bile acids on biliary epithelial cells: proliferation, cytotoxicity, and cytokine secretion

Effects of long-term administration of interferon α in two models of liver fibrosis in rats

Expression and activity of the cytolethal distending toxin of Helicobacter hepaticus

Expression and cellular localization of fibrillin-1 in normal and pathological human liver

Expression and cellular localization of the urokinase-type plasminogen activator and its receptor in human hepatocellular carcinoma

Expression of collagens type I and IV, osteonectin and transforming growth factor beta-1 (TGFbeta1) in biliary atresia and paucity of intrahepatic bile ducts during infancy

Expression of hepatocyte growth factor in human hepatocellular carcinoma

Expression of leukemia inhibitory factor (LIF) and its receptor gp190 in human liver and in cultured human liver myofibroblasts. Cloning of new isoforms of LIF mRNA

Expression of protease-activated receptors and tissue factor in human liver

Extracellular matrix composition and integrin expression in early hepatocarcinogenesis in human cirrhotic liver

Extracellular matrix rigidity controls podosome induction in microvascular endothelial cells.

Fibroblast growth factor 2 and transforming growth factor beta 1 interactions in human liver myofibroblasts

First identification of small-molecule inhibitors of Pontin by combining virtual screening and enzymatic assay

Halofuginone suppresses the lung metastasis of chemically induced hepatocellular carcinoma in rats through MMP inhibition.

Heparan sulfate proteoglycan expression in chronic cholestatic human liver diseases

Hepatic lesions observed in hepatitis C virus transgenic mice infected by Helicobacter hepaticus

Hepatitis C virus proteins do not directly trigger fibrogenic events in cultured human liver myofibroblasts

Immunohistochemical detection of hcv in cirrhosis, dysplastic nodules, and hepatocellular carcinomas with parallel-tissue quantitative RT-PCR.

In vivo MR imaging of intravascularly injected magnetically labeled mesenchymal stem cells in rat kidney and liver.

In vivo silencing of Reptin blocks the progression of human hepatocellular carcinoma in xenografts and is associated with replicative senescence

Inhibition of rat liver fibrogenesis through noradrenergic antagonism

Integrative quantitative proteomics unveils proteostasis imbalance in human hepatocellular carcinoma developed on nonfibrotic livers

Involvement of matrix metalloproteinase type-3 in hepatocyte growth factor-induced invasion of human hepatocellular carcinoma cells

Liver Reptin/RUVBL2 controls glucose and lipid metabolism with opposite actions on mTORC1 and mTORC2 signalling

Liver myofibroblasts activate protein C and respond to activated protein C.

Matrix metalloproteinase 3 is present in the cell nucleus and is involved in apoptosis.

Metalloproteinase meprin α regulates migration and invasion of human hepatocarcinoma cells and is a mediator of the oncoprotein Reptin

Mitogenic effect of transforming growth factor-beta 1 on human Ito cells in culture: evidence for mediation by endogenous platelet-derived growth factor

Myofibroblasts are responsible for collagen synthesis in the stroma of human hepatocellular carcinoma: an in vivo and in vitro study

Osteonectin/SPARC is overexpressed in human hepatocellular carcinoma

Overexpression and role of the ATPase and putative DNA helicase RuvB-like 2 in human hepatocellular carcinoma

PAV-1, a new rat hepatic stellate cell line converts retinol into retinoic acid, a process altered by ethanol.

Paradoxical pro-invasive effect of the serine proteinase inhibitor tissue factor pathway inhibitor-2 on human hepatocellular carcinoma cells.

Pentoxifylline inhibits growth and collagen synthesis of cultured human hepatic myofibroblast-like cells

Physiological type I collagen organization induces the formation of a novel class of linear invadosomes

Pontin and reptin, two related ATPases with multiple roles in cancer.

Posttranscriptional regulation of PER1 underlies the oncogenic function of IREα.

Protease-activated receptor 1 knockout reduces experimentally induced liver fibrosis

Proteomic analysis of differentially expressed proteins in hepatocellular carcinoma developed in patients with chronic viral hepatitis C.

Reptin regulates DNA double strand breaks repair in human hepatocellular carcinoma

Reptin regulates insulin-stimulated Akt phosphorylation in hepatocellular carcinoma via the regulation of SHP-1/PTPN6.

Restricted expression of membrane type 1-matrix metalloproteinase by myofibroblasts adjacent to human breast cancer cells

Rnd3/RhoE Is down-regulated in hepatocellular carcinoma and controls cellular invasion

Sorafenib-mediated targeting of the AAA⁺ ATPase p97/VCP leads to disruption of the secretory pathway, endoplasmic reticulum stress, and hepatocellular cancer cell death

The ARE-associated factor AUF1 binds poly(A) in vitro in competition with PABP.

The ATPase activity of reptin is required for its effects on tumor cell growth and viability in hepatocellular carcinoma

The Oxygen Paradox, the French Paradox, and age-related diseases.

The emergence of the conserved AAA+ ATPases Pontin and Reptin on the signaling landscape

The grape-derived polyphenol resveratrol differentially affects epidermal and platelet-derived growth factor signaling in human liver myofibroblasts.

The multifaceted proteins Reptin and Pontin as major players in cancer

Thrombin up-regulates tissue factor pathway inhibitor-2 synthesis through a cyclooxygenase-2-dependent, epidermal growth factor receptor-independent mechanism

Vitamin A-guided siRNAs targeting a collagen chaperone can reverse experimental cirrhosis

[A little less respite for hepatocellular carcinoma?]

[Fundamental and translational research on hepatocellular carcinoma in 2008: forces and priorities]

[Mechanisms of hepatic fibrogenesis]