Lista de obras - Floris Foijer - Dominio Público Uruguay

A haploid genetic screen identifies the G1/S regulatory machinery as a determinant of Wee1 inhibitor sensitivity.

artículo científico publicado en 2015

A living biobank of ovarian cancer ex vivo models reveals profound mitotic heterogeneity

artículo científico publicado en 2020

Abstracts from the 3rd Conference on Aneuploidy and Cancer: Clinical and Experimental Aspects: Berkeley, CA, USA. 26 - 29 January 2017.

artículo científico publicado en 2017

Altering microtubule dynamics is synergistically toxic with spindle assembly checkpoint inhibition

artículo científico publicado en 2020

Analysis of mitosis and antimitotic drug responses in tumors by in vivo microscopy and single-cell pharmacodynamics.

artículo científico publicado en 2011

Anchorage-independent growth of pocket protein-deficient murine fibroblasts requires bypass of G2 arrest and can be accomplished by expression of TBX2.

artículo científico publicado en 2008

Aneuploidy in stem cells

artículo científico publicado en 2016

Aneuploidy renders cancer cells vulnerable to mitotic checkpoint inhibition

artículo científico publicado en 2021

Better check late than never: The chromosome segregation checkpoint (comment on DOI 10.1002/bies.201400140)

artículo científico publicado en 2015

BubR1 allelic effects drive phenotypic heterogeneity in mosaic-variegated aneuploidy progeria syndrome

artículo científico publicado en 2020

CIN and Aneuploidy: Different Concepts, Different Consequences.

artículo científico publicado en 2017

CINcere Modelling: What Have Mouse Models for Chromosome Instability Taught Us?

artículo científico

CINister thoughts ⬇️

artículo científico publicado el 1 de diciembre de 2010

Centrosome Amplification Is Sufficient to Promote Spontaneous Tumorigenesis in Mammals

artículo científico publicado en 2017

Centrosome defects cause microcephaly by activating the 53BP1-USP28-TP53 mitotic surveillance pathway

artículo científico publicado en 2020

Characterization of the condensin component Cnap1 and protein kinase Melk as novel E2F target genes down-regulated by 1,25-dihydroxyvitamin D3.

artículo científico publicado en 2005

Check, double check: the G2 barrier to cancer.

artículo científico publicado en 2006

Chromosomal Instability Characterizes Pediatric Medulloblastoma but Is Not Tolerated in the Developing Cerebellum

artículo científico publicado en 2022

Chromosome instability induced by Mps1 and p53 mutation generates aggressive lymphomas exhibiting aneuploidy-induced stress.

artículo científico publicado en 2014

Copy number alterations assessed at the single-cell level revealed mono- and polyclonal seeding patterns of distant metastasis in a small cell lung cancer patient.

artículo científico publicado en 2017

Deletion of the MAD2L1 spindle assembly checkpoint gene is tolerated in mouse models of acute T-cell lymphoma and hepatocellular carcinoma

artículo científico publicado en 2017

E2F-Family Members Engage the PIDDosome to Limit Hepatocyte Ploidy in Liver Development and Regeneration

artículo científico publicado en 2020

Erratum to: Single-cell whole genome sequencing reveals no evidence for common aneuploidy in normal and Alzheimer's disease neurons.

artículo científico publicado en 2016

FoxM1 repression during human aging leads to mitotic decline and aneuploidy-driven full senescence

scientific article published in Nature Communications

Genetic instability from a single S phase after whole-genome duplication

artículo científico publicado en 2022

How to count chromosomes in a cell: An overview of current and novel technologies

artículo científico publicado en 2015

Identification of Two Protein-Signaling States Delineating Transcriptionally Heterogeneous Human Medulloblastoma.

artículo científico publicado en 2018

In vivo significance of the G2 restriction point.

artículo científico publicado en 2007

Loss of Rb proteins causes genomic instability in the absence of mitogenic signaling

artículo científico publicado en 2010

Loss of p53 suppresses replication-stress-induced DNA breakage in G1/S checkpoint deficient cells

artículo científico publicado en 2018

Mitogen requirement for cell cycle progression in the absence of pocket protein activity

artículo científico publicado en 2005

Non-random Mis-segregation of Human Chromosomes.

artículo científico publicado en 2018

Oncogenic pathways impinging on the G2-restriction point

artículo científico publicado en 2007

Ongoing chromosomal instability and karyotype evolution in human colorectal cancer organoids

artículo científico publicado en 2019

PIDDosome-induced p53-dependent ploidy restriction facilitates hepatocarcinogenesis

artículo científico publicado en 2020

Progression through mitosis promotes PARP inhibitor-induced cytotoxicity in homologous recombination-deficient cancer cells

artículo científico publicado en 2017

Quantification of Aneuploidy in Mammalian Systems

artículo científico publicado en 2019

RNAi screening of subtracted transcriptomes reveals tumor suppression by taurine-activated GABAA receptors involved in volume regulation.

artículo científico publicado en 2018

Replication catastrophe is responsible for intrinsic PAR glycohydrolase inhibitor-sensitivity in patient-derived ovarian cancer models

artículo científico publicado en 2021

Restriction beyond the restriction point: mitogen requirement for G2 passage

artículo científico publicado en 2006

Revisiting the chromosome separation checkpoint (retrospective on DOI 10.1002/bies.201400140).

artículo científico publicado en 2017

Single-cell sequencing reveals karyotype heterogeneity in murine and human malignancies

artículo científico publicado en 2016

Single-cell sequencing to quantify genomic integrity in cancer

artículo científico publicado en 2017

Single-cell whole genome sequencing reveals no evidence for common aneuploidy in normal and Alzheimer's disease neurons

artículo científico publicado en 2016

Spindle checkpoint deficiency is tolerated by murine epidermal cells but not hair follicle stem cells

artículo científico publicado en 2013

TP53 loss initiates chromosomal instability in fallopian tube epithelial cells

artículo científico publicado en 2021

TPX2/Aurora kinase A signaling as a potential therapeutic target in genomically unstable cancer cells

artículo científico publicado en 2018

The H3.3K27M oncohistone affects replication stress outcome and provokes genomic instability in pediatric glioma

artículo científico publicado en 2021

The cGAS Paradox: Contrasting Roles for cGAS-STING Pathway in Chromosomal Instability

scientific article published on 10 October 2019

The p38α Stress Kinase Suppresses Aneuploidy Tolerance by Inhibiting Hif-1α

scientific article published on 01 October 2018

Transient genomic instability drives tumorigenesis through accelerated clonal evolution

artículo científico publicado en 2021

p53 Prohibits Propagation of Chromosome Segregation Errors that Produce Structural Aneuploidies

artículo científico publicado en 2017

Lista de obras de Floris Foijer

A haploid genetic screen identifies the G1/S regulatory machinery as a determinant of Wee1 inhibitor sensitivity.

A living biobank of ovarian cancer ex vivo models reveals profound mitotic heterogeneity

Abstracts from the 3rd Conference on Aneuploidy and Cancer: Clinical and Experimental Aspects: Berkeley, CA, USA. 26 - 29 January 2017.

Altering microtubule dynamics is synergistically toxic with spindle assembly checkpoint inhibition

Analysis of mitosis and antimitotic drug responses in tumors by in vivo microscopy and single-cell pharmacodynamics.

Anchorage-independent growth of pocket protein-deficient murine fibroblasts requires bypass of G2 arrest and can be accomplished by expression of TBX2.

Aneuploidy in stem cells

Aneuploidy renders cancer cells vulnerable to mitotic checkpoint inhibition

Better check late than never: The chromosome segregation checkpoint (comment on DOI 10.1002/bies.201400140)

BubR1﻿﻿ allelic effects drive phenotypic heterogeneity in mosaic-variegated aneuploidy progeria syndrome

CIN and Aneuploidy: Different Concepts, Different Consequences.

CINcere Modelling: What Have Mouse Models for Chromosome Instability Taught Us?

CINister thoughts ⬇️

Centrosome Amplification Is Sufficient to Promote Spontaneous Tumorigenesis in Mammals

Centrosome defects cause microcephaly by activating the 53BP1-USP28-TP53 mitotic surveillance pathway

Characterization of the condensin component Cnap1 and protein kinase Melk as novel E2F target genes down-regulated by 1,25-dihydroxyvitamin D3.

Check, double check: the G2 barrier to cancer.

Chromosomal Instability Characterizes Pediatric Medulloblastoma but Is Not Tolerated in the Developing Cerebellum

Chromosome instability induced by Mps1 and p53 mutation generates aggressive lymphomas exhibiting aneuploidy-induced stress.

Copy number alterations assessed at the single-cell level revealed mono- and polyclonal seeding patterns of distant metastasis in a small cell lung cancer patient.

Deletion of the MAD2L1 spindle assembly checkpoint gene is tolerated in mouse models of acute T-cell lymphoma and hepatocellular carcinoma

E2F-Family Members Engage the PIDDosome to Limit Hepatocyte Ploidy in Liver Development and Regeneration

Erratum to: Single-cell whole genome sequencing reveals no evidence for common aneuploidy in normal and Alzheimer's disease neurons.

FoxM1 repression during human aging leads to mitotic decline and aneuploidy-driven full senescence

Genetic instability from a single S phase after whole-genome duplication

How to count chromosomes in a cell: An overview of current and novel technologies

Identification of Two Protein-Signaling States Delineating Transcriptionally Heterogeneous Human Medulloblastoma.

In vivo significance of the G2 restriction point.

Loss of Rb proteins causes genomic instability in the absence of mitogenic signaling

Loss of p53 suppresses replication-stress-induced DNA breakage in G1/S checkpoint deficient cells

Mitogen requirement for cell cycle progression in the absence of pocket protein activity

Non-random Mis-segregation of Human Chromosomes.

Oncogenic pathways impinging on the G2-restriction point

Ongoing chromosomal instability and karyotype evolution in human colorectal cancer organoids

PIDDosome-induced p53-dependent ploidy restriction facilitates hepatocarcinogenesis

Progression through mitosis promotes PARP inhibitor-induced cytotoxicity in homologous recombination-deficient cancer cells

Quantification of Aneuploidy in Mammalian Systems

RNAi screening of subtracted transcriptomes reveals tumor suppression by taurine-activated GABAA receptors involved in volume regulation.

Replication catastrophe is responsible for intrinsic PAR glycohydrolase inhibitor-sensitivity in patient-derived ovarian cancer models

Restriction beyond the restriction point: mitogen requirement for G2 passage

Revisiting the chromosome separation checkpoint (retrospective on DOI 10.1002/bies.201400140).

Single-cell sequencing reveals karyotype heterogeneity in murine and human malignancies

Single-cell sequencing to quantify genomic integrity in cancer

Single-cell whole genome sequencing reveals no evidence for common aneuploidy in normal and Alzheimer's disease neurons

Spindle checkpoint deficiency is tolerated by murine epidermal cells but not hair follicle stem cells

TP53 loss initiates chromosomal instability in fallopian tube epithelial cells

TPX2/Aurora kinase A signaling as a potential therapeutic target in genomically unstable cancer cells

The H3.3K27M oncohistone affects replication stress outcome and provokes genomic instability in pediatric glioma

The cGAS Paradox: Contrasting Roles for cGAS-STING Pathway in Chromosomal Instability

The p38α Stress Kinase Suppresses Aneuploidy Tolerance by Inhibiting Hif-1α

Transient genomic instability drives tumorigenesis through accelerated clonal evolution

p53 Prohibits Propagation of Chromosome Segregation Errors that Produce Structural Aneuploidies

BubR1 allelic effects drive phenotypic heterogeneity in mosaic-variegated aneuploidy progeria syndrome