Lista de obras - Elissa K. Deenick - Dominio Público Uruguay

A divergent transcriptional landscape underpins the development and functional branching of MAIT cells

artículo científico publicado en 2019

A recessive form of hyper-IgE syndrome by disruption of ZNF341-dependent STAT3 transcription and activity

scientific article published on 01 June 2018

Activating PIK3CD mutations impair human cytotoxic lymphocyte differentiation, function and EBV immunity.

artículo científico publicado en 2018

Activating mutations in PIK3CD disrupt the differentiation and function of human and murine CD4+ T cells

scientific article published on 06 February 2019

B cell-intrinsic requirement for STK4 in humoral immunity in mice and human subjects

artículo científico publicado en 2019

B cell-intrinsic signaling through IL-21 receptor and STAT3 is required for establishing long-lived antibody responses in humans

artículo científico publicado en 2010

B cells: we need them now more than ever

scientific article published on 01 July 2020

B-cell-specific STAT3 deficiency: Insight into the molecular basis of autosomal-dominant hyper-IgE syndrome.

artículo científico publicado en 2016

Cytokine-Mediated Regulation of Human Lymphocyte Development and Function: Insights from Primary Immunodeficiencies.

artículo científico publicado en 2017

Decision criteria for resolving isotype switching conflicts by B cells

artículo científico publicado en 2005

Disruption of an antimycobacterial circuit between dendritic and helper T cells in human SPPL2a deficiency

scientific article published on 20 August 2018

Dock8 mutations cripple B cell immunological synapses, germinal centers and long-lived antibody production.

artículo científico publicado en 2009

Dominant-activating germline mutations in the gene encoding the PI(3)K catalytic subunit p110δ result in T cell senescence and human immunodeficiency

artículo científico publicado en 2013

Early commitment of naïve human CD4(+) T cells to the T follicular helper (T(FH)) cell lineage is induced by IL-12.

artículo científico publicado en 2009

Elucidating the effects of disease-causing mutations on STAT3 function in autosomal-dominant hyper-IgE syndrome

scientific article published on 13 May 2016

Erratum: The circulating life of a memory T-follicular helper cell

artículo científico publicado en 2017

Follicular helper T cell differentiation requires continuous antigen presentation that is independent of unique B cell signaling.

artículo científico publicado en 2010

Functional STAT3 deficiency compromises the generation of human T follicular helper cells.

artículo científico publicado en 2012

Generation and characterization of B7-H4/B7S1/B7x-deficient mice

scientific journal article

Germline-activating mutations in PIK3CD compromise B cell development and function

artículo científico publicado en 2018

Human IFN-γ immunity to mycobacteria is governed by both IL-12 and IL-23

artículo científico publicado en 2018

Human T follicular helper (Tfh) cells and disease

artículo científico publicado en 2013

Human Th9 cells: inflammatory cytokines modulate IL-9 production through the induction of IL-21

scientific article published on 08 June 2010

IMMUNODEFICIENCIES. Impairment of immunity to Candida and Mycobacterium in humans with bi-allelic RORC mutations

artículo científico publicado en 2015

Immune Dysregulation and Disease Pathogenesis due to Activating Mutations in PIK3CD-the Goldilocks' Effect

scientific article published on 01 February 2019

Immune dysregulation in human subjects with heterozygous germline mutations in CTLA4

artículo científico publicado en 2014

Immunology: Helpful T cells are sticky

artículo científico publicado en 2008

Molecular Pathogenesis of EBV Susceptibility in XLP as Revealed by Analysis of Female Carriers with Heterozygous Expression of SAP ⬇️

artículo científico publicado el 1 de noviembre de 2011

Monogenic mutations differentially affect the quantity and quality of T follicular helper cells in patients with human primary immunodeficiencies

artículo científico publicado en 2015

Naive and memory human B cells have distinct requirements for STAT3 activation to differentiate into antibody-secreting plasma cells.

artículo científico publicado en 2013

Potent antitumour activity of interleukin-2-Fc fusion proteins requires Fc-mediated depletion of regulatory T-cells

artículo científico publicado en 2017

Regulation of T follicular helper cell formation and function by antigen presenting cells.

artículo científico publicado en 2010

STAT3 is a central regulator of lymphocyte differentiation and function.

artículo científico

STAT3 is a critical cell-intrinsic regulator of human unconventional T cell numbers and function

artículo científico publicado en 2015

Signal Transducer and Activator of Transcription 3 Control of Human T and B Cell Responses

artículo científico publicado en 2018

Signal transducer and activator of transcription 3 (STAT3) mutations underlying autosomal dominant hyper-IgE syndrome impair human CD8(+) T-cell memory formation and function.

scientific article published on 04 July 2013

T cell-B cell interactions in primary immunodeficiencies

artículo científico publicado en 2012

T follicular helper cells have distinct modes of migration and molecular signatures in naive and memory immune responses.

artículo científico publicado en 2015

TCR affinity and negative regulation limit autoimmunity

article

The TORC that Gets the GC Cycling.

artículo científico publicado en 2017

The good, the bad and the ugly - TFH cells in human health and disease

artículo científico

The origins, function, and regulation of T follicular helper cells ⬇️

artículo científico publicado el 2 de julio de 2012

The regulation and role of T follicular helper cells in immunity ⬇️

artículo científico publicado el 1 de diciembre de 2011

The role of SAP and SLAM family molecules in the humoral immune response ⬇️

artículo científico publicado el 22 de noviembre de 2010

The sound of silence: modulating anergy in T lymphocytes.

artículo científico publicado en 2007

Unique and shared signaling pathways cooperate to regulate the differentiation of human CD4+ T cells into distinct effector subsets.

artículo científico publicado en 2016

c-Rel but not NF-κB1 is important for T regulatory cell development

artículo científico publicado en 2010

c-Rel phenocopies PKCtheta but not Bcl-10 in regulating CD8+ T-cell activation versus tolerance.

artículo científico publicado en 2010

Lista de obras de Elissa K. Deenick

A divergent transcriptional landscape underpins the development and functional branching of MAIT cells

A recessive form of hyper-IgE syndrome by disruption of ZNF341-dependent STAT3 transcription and activity

Activating PIK3CD mutations impair human cytotoxic lymphocyte differentiation, function and EBV immunity.

Activating mutations in PIK3CD disrupt the differentiation and function of human and murine CD4+ T cells

B cell-intrinsic requirement for STK4 in humoral immunity in mice and human subjects

B cell-intrinsic signaling through IL-21 receptor and STAT3 is required for establishing long-lived antibody responses in humans

B cells: we need them now more than ever

B-cell-specific STAT3 deficiency: Insight into the molecular basis of autosomal-dominant hyper-IgE syndrome.

Cytokine-Mediated Regulation of Human Lymphocyte Development and Function: Insights from Primary Immunodeficiencies.

Decision criteria for resolving isotype switching conflicts by B cells

Disruption of an antimycobacterial circuit between dendritic and helper T cells in human SPPL2a deficiency

Dock8 mutations cripple B cell immunological synapses, germinal centers and long-lived antibody production.

Dominant-activating germline mutations in the gene encoding the PI(3)K catalytic subunit p110δ result in T cell senescence and human immunodeficiency

Early commitment of naïve human CD4(+) T cells to the T follicular helper (T(FH)) cell lineage is induced by IL-12.

Elucidating the effects of disease-causing mutations on STAT3 function in autosomal-dominant hyper-IgE syndrome

Erratum: The circulating life of a memory T-follicular helper cell

Follicular helper T cell differentiation requires continuous antigen presentation that is independent of unique B cell signaling.

Functional STAT3 deficiency compromises the generation of human T follicular helper cells.

Generation and characterization of B7-H4/B7S1/B7x-deficient mice

Germline-activating mutations in PIK3CD compromise B cell development and function

Human IFN-γ immunity to mycobacteria is governed by both IL-12 and IL-23

Human T follicular helper (Tfh) cells and disease

Human Th9 cells: inflammatory cytokines modulate IL-9 production through the induction of IL-21

IMMUNODEFICIENCIES. Impairment of immunity to Candida and Mycobacterium in humans with bi-allelic RORC mutations

Immune Dysregulation and Disease Pathogenesis due to Activating Mutations in PIK3CD-the Goldilocks' Effect

Immune dysregulation in human subjects with heterozygous germline mutations in CTLA4

Immunology: Helpful T cells are sticky

Molecular Pathogenesis of EBV Susceptibility in XLP as Revealed by Analysis of Female Carriers with Heterozygous Expression of SAP ⬇️

Monogenic mutations differentially affect the quantity and quality of T follicular helper cells in patients with human primary immunodeficiencies

Naive and memory human B cells have distinct requirements for STAT3 activation to differentiate into antibody-secreting plasma cells.

Potent antitumour activity of interleukin-2-Fc fusion proteins requires Fc-mediated depletion of regulatory T-cells

Regulation of T follicular helper cell formation and function by antigen presenting cells.

STAT3 is a central regulator of lymphocyte differentiation and function.

STAT3 is a critical cell-intrinsic regulator of human unconventional T cell numbers and function

Signal Transducer and Activator of Transcription 3 Control of Human T and B Cell Responses

Signal transducer and activator of transcription 3 (STAT3) mutations underlying autosomal dominant hyper-IgE syndrome impair human CD8(+) T-cell memory formation and function.

T cell-B cell interactions in primary immunodeficiencies

T follicular helper cells have distinct modes of migration and molecular signatures in naive and memory immune responses.

TCR affinity and negative regulation limit autoimmunity

The TORC that Gets the GC Cycling.

The good, the bad and the ugly - TFH cells in human health and disease

The origins, function, and regulation of T follicular helper cells ⬇️

The regulation and role of T follicular helper cells in immunity ⬇️

The role of SAP and SLAM family molecules in the humoral immune response ⬇️

The sound of silence: modulating anergy in T lymphocytes.

Unique and shared signaling pathways cooperate to regulate the differentiation of human CD4+ T cells into distinct effector subsets.

c-Rel but not NF-κB1 is important for T regulatory cell development

c-Rel phenocopies PKCtheta but not Bcl-10 in regulating CD8+ T-cell activation versus tolerance.