Lista de obras - Simon D Wagner - Dominio Público Uruguay

A Double Hit CD10-Negative B-Cell Lymphoma with t(3;8)(q27;q24) Leading to Juxtaposition of the BCL6 and MYC Loci Associated with Good Clinical Outcome.

artículo científico publicado en 2014

A peptide aptamer to antagonize BCL-6 function.

artículo científico publicado en 2006

Alpha6-integrin is expressed on germinal centre B cells and modifies growth of a B-cell line

artículo científico publicado en 2004

An increased fraction of circulating miR-363 and miR-16 is particle bound in patients with chronic lymphocytic leukaemia as compared to normal subjects. ⬇️

artículo científico publicado en 2018

Antibodies generated from human immunoglobulin miniloci in transgenic mice

artículo científico publicado en 1994

Antibody expression from the core region of the human IgH locus reconstructed in transgenic mice using bacteriophage P1 clones

artículo científico publicado en 1996

Apoptosis induces Bcl-XS and cleaved Bcl-XL in chronic lymphocytic leukaemia

artículo científico publicado en 2011

Arrested differentiation, the self-renewing memory lymphocyte, and vaccination.

artículo científico publicado en 2001

BCL-6 is expressed in breast cancer and prevents mammary epithelial differentiation

artículo científico publicado en 2003

BCL-6: rearrangement and mutation in lymphoma.

artículo científico publicado en 2005

Bcl-6 and c-Myc are rarely co-expressed in adult diffuse large B-cell lymphoma.

artículo científico publicado en 2007

CD154 induces a switch in pro-survival Bcl-2 family members in chronic lymphocytic leukaemia.

artículo científico publicado en 2007

CD40 and B-cell receptor signalling induce MAPK family members that can either induce or repress Bcl-6 expression

artículo científico publicado en 2009

CD40L/IL-4-stimulated CLL demonstrates variation in translational regulation of DNA damage response genes including ATM

article

CD49d is an independent prognostic marker that is associated with CXCR4 expression in CLL.

artículo científico publicado en 2010

Cap-translation inhibitor, 4EGI-1, restores sensitivity to ABT-737 apoptosis through cap-dependent and -independent mechanisms in chronic lymphocytic leukemia

artículo científico publicado en 2013

Chronic lymphocytic leukaemia: new biological markers for assessing prognosis.

artículo científico publicado en 2004

Circulating Tfh1 (cTfh1) cell numbers and PD1 expression are elevated in low-grade B-cell non-Hodgkin's lymphoma and cTfh gene expression is perturbed in marginal zone lymphoma

artículo científico publicado en 2018

Codon bias targets mutation.

artículo científico publicado en 1995

Comparison of interleukin-2-inducible kinase (ITK) inhibitors and potential for combination therapies for T-cell lymphoma

scientific article published in Scientific Reports

Defining the prognosis of early stage chronic lymphocytic leukaemia patients

artículo científico publicado en 2011

Enhancement of CD154/IL4 proliferation by the T follicular helper (Tfh) cytokine, IL21 and increased numbers of circulating cells resembling Tfh cells in chronic lymphocytic leukaemia.

artículo científico publicado en 2013

Expression of PD-1 (CD279) and FoxP3 in diffuse large B-cell lymphoma

artículo científico publicado en 2014

Follicular helper T-cells: expanding roles in T-cell lymphoma and targets for treatment.

artículo científico publicado en 2014

Guidelines on the diagnosis and management of Waldenström macroglobulinaemia.

artículo científico publicado en 2014

IKKε and TBK1 in diffuse large B-cell lymphoma: A possible mechanism of action of an IKKε/TBK1 inhibitor to repress NF-κB and IL-10 signalling

artículo científico publicado en 2020

IL-4, IgM, and resistance to BTKi and PI3Kδi in CLL.

artículo científico publicado en 2016

Interleukin-2-inducible T-cell kinase inhibitors modify functional polarization of human peripheral T-cell lymphoma cells

artículo científico publicado en 2019

Interphase FISH using aBCL3probe to diagnose the t(14;19)(q32;q13)-positive small B-cell leukemia

artículo científico publicado en 2008

Nocodazole, a microtubule de-polymerising agent, induces apoptosis of chronic lymphocytic leukaemia cells associated with changes in Bcl-2 phosphorylation and expression

artículo científico publicado en 2005

Novel CTCF binding at a site in exon1A of BCL6 is associated with active histone marks and a transcriptionally active locus

artículo científico publicado en 2013

PD1 cells associate with clusters of proliferating B-cells in marginal zone lymphoma

artículo científico publicado en 2018

POZ-, AT-hook-, and zinc finger-containing protein (PATZ) interacts with human oncogene B cell lymphoma 6 (BCL6) and is required for its negative autoregulation

scientific article published in 2014

POZ-, AT-hook-, and zinc finger-containing protein (PATZ) interacts with human oncogene B cell lymphoma 6 (BCL6) and is required for its negative autoregulation.

artículo científico publicado en 2012

Poly(ADP-ribose) polymerase-1 (Parp-1)-deficient mice demonstrate abnormal antibody responses.

artículo científico publicado en 2008

Poly-(ADP-ribose) polymerase-1 (Parp-1) binds in a sequence-specific manner at the Bcl-6 locus and contributes to the regulation of Bcl-6 transcription

artículo científico publicado en 2007

Post-transcriptional and post-translational regulation of Bcl2.

artículo científico publicado en 2010

Precision medicines for B-cell leukaemias and lymphomas; progress and potential pitfalls

artículo científico publicado en 2013

Regulation of CD38 in proliferating chronic lymphocytic leukemia cells stimulated with CD154 and interleukin-4.

artículo científico publicado en 2007

STAT6-mediated BCL6 repression in primary mediastinal B-cell lymphoma (PMBL).

artículo científico publicado en 2013

Separate cell culture conditions to promote proliferation or quiescent cell survival in chronic lymphocytic leukemia.

artículo científico publicado en 2007

Similar patterns of V kappa gene usage but different degrees of somatic mutation in hairy cell leukemia, prolymphocytic leukemia, Waldenstrom's macroglobulinemia, and myeloma

artículo científico publicado en 1994

Somatic hypermutation of Ig genes in patients with xeroderma pigmentosum (XP-D)

artículo científico publicado en 1996

Somatic hypermutation of immunoglobulin genes

artículo científico publicado en 1996

Specific patterns of chromosomal gains and losses associate with t(3;14), t(8;14), and t(14;18) in diffuse large B-cell lymphoma

artículo científico publicado en 2009

Stromal cells and CD40 ligand (CD154) alter the miRNome and induce miRNA clusters including, miR-125b/miR-99a/let-7c and miR-17-92 in chronic lymphocytic leukaemia

scientific article published on 25 October 2011

Structural and diffusion weighted MRI demonstrates responses to ibrutinib in a mouse model of follicular helper (Tfh) T-cell lymphoma

article

Structure-function studies of an engineered scaffold protein derived from Stefin A. II: Development and applications of the SQT variant

artículo científico publicado en 2011

Structure-function studies of an engineered scaffold protein derived from stefin A. I: Development of the SQM variant.

artículo científico publicado en 2010

Suppression of signal transducer and activator of transcription 3-dependent B lymphocyte terminal differentiation by BCL-6.

artículo científico publicado en 2000

TP53 codon 72 polymorphism in patients with chronic lymphocytic leukaemia: identification of a subgroup with mutated IGHV genes and poor clinical outcome

artículo científico publicado en 2011

Targeting primary mediastinal B-cell lymphoma

artículo científico publicado en 2014

The ansamycin antibiotic, rifamycin SV, inhibits BCL6 transcriptional repression and forms a complex with the BCL6-BTB/POZ domain

artículo científico publicado en 2014

The diversity of antigen-specific monoclonal antibodies from transgenic mice bearing human immunoglobulin gene miniloci

scientific article published on 01 November 1994

The level of BCR-ABL1 kinase activity before treatment does not identify chronic myeloid leukemia patients who fail to achieve a complete cytogenetic response on imatinib

artículo científico publicado en 2009

The new biology of PTCL-NOS and AITL: current status and future clinical impact

artículo científico publicado en 2020

The role of BCL6 in lymphomas and routes to therapy

artículo científico publicado en 2010

The targeting of somatic hypermutation

artículo científico publicado en 1996

V kappa gene segments rearranged in chronic lymphocytic leukemia are distributed over a large portion of the V kappa locus and do not show somatic mutation

artículo científico publicado en 1993

V lambda genes in chronic lymphocytic leukaemia: highly skewed V gene segment usage with similar CDR3 sequences

scientific article published on 01 November 2007

ZEB1 and CtBP form a repressive complex at a distal promoter element of the BCL6 locus

artículo científico publicado en 2010

miR-125b and miR-155 contribute to BCL2 repression and proliferation in response to CD40 ligand (CD154) in human leukemic B-cells

artículo científico publicado en 2011

Lista de obras de Simon D Wagner

A Double Hit CD10-Negative B-Cell Lymphoma with t(3;8)(q27;q24) Leading to Juxtaposition of the BCL6 and MYC Loci Associated with Good Clinical Outcome.

A peptide aptamer to antagonize BCL-6 function.

Alpha6-integrin is expressed on germinal centre B cells and modifies growth of a B-cell line

An increased fraction of circulating miR-363 and miR-16 is particle bound in patients with chronic lymphocytic leukaemia as compared to normal subjects. ⬇️

Antibodies generated from human immunoglobulin miniloci in transgenic mice

Antibody expression from the core region of the human IgH locus reconstructed in transgenic mice using bacteriophage P1 clones

Apoptosis induces Bcl-XS and cleaved Bcl-XL in chronic lymphocytic leukaemia

Arrested differentiation, the self-renewing memory lymphocyte, and vaccination.

BCL-6 is expressed in breast cancer and prevents mammary epithelial differentiation

BCL-6: rearrangement and mutation in lymphoma.

Bcl-6 and c-Myc are rarely co-expressed in adult diffuse large B-cell lymphoma.

CD154 induces a switch in pro-survival Bcl-2 family members in chronic lymphocytic leukaemia.

CD40 and B-cell receptor signalling induce MAPK family members that can either induce or repress Bcl-6 expression

CD40L/IL-4-stimulated CLL demonstrates variation in translational regulation of DNA damage response genes including ATM

CD49d is an independent prognostic marker that is associated with CXCR4 expression in CLL.

Cap-translation inhibitor, 4EGI-1, restores sensitivity to ABT-737 apoptosis through cap-dependent and -independent mechanisms in chronic lymphocytic leukemia

Chronic lymphocytic leukaemia: new biological markers for assessing prognosis.

Circulating Tfh1 (cTfh1) cell numbers and PD1 expression are elevated in low-grade B-cell non-Hodgkin's lymphoma and cTfh gene expression is perturbed in marginal zone lymphoma

Codon bias targets mutation.

Comparison of interleukin-2-inducible kinase (ITK) inhibitors and potential for combination therapies for T-cell lymphoma

Defining the prognosis of early stage chronic lymphocytic leukaemia patients

Enhancement of CD154/IL4 proliferation by the T follicular helper (Tfh) cytokine, IL21 and increased numbers of circulating cells resembling Tfh cells in chronic lymphocytic leukaemia.

Expression of PD-1 (CD279) and FoxP3 in diffuse large B-cell lymphoma

Follicular helper T-cells: expanding roles in T-cell lymphoma and targets for treatment.

Guidelines on the diagnosis and management of Waldenström macroglobulinaemia.

IKKε and TBK1 in diffuse large B-cell lymphoma: A possible mechanism of action of an IKKε/TBK1 inhibitor to repress NF-κB and IL-10 signalling

IL-4, IgM, and resistance to BTKi and PI3Kδi in CLL.

Interleukin-2-inducible T-cell kinase inhibitors modify functional polarization of human peripheral T-cell lymphoma cells

Interphase FISH using aBCL3probe to diagnose the t(14;19)(q32;q13)-positive small B-cell leukemia

Nocodazole, a microtubule de-polymerising agent, induces apoptosis of chronic lymphocytic leukaemia cells associated with changes in Bcl-2 phosphorylation and expression

Novel CTCF binding at a site in exon1A of BCL6 is associated with active histone marks and a transcriptionally active locus

PD1 cells associate with clusters of proliferating B-cells in marginal zone lymphoma

POZ-, AT-hook-, and zinc finger-containing protein (PATZ) interacts with human oncogene B cell lymphoma 6 (BCL6) and is required for its negative autoregulation

POZ-, AT-hook-, and zinc finger-containing protein (PATZ) interacts with human oncogene B cell lymphoma 6 (BCL6) and is required for its negative autoregulation.

Poly(ADP-ribose) polymerase-1 (Parp-1)-deficient mice demonstrate abnormal antibody responses.

Poly-(ADP-ribose) polymerase-1 (Parp-1) binds in a sequence-specific manner at the Bcl-6 locus and contributes to the regulation of Bcl-6 transcription

Post-transcriptional and post-translational regulation of Bcl2.

Precision medicines for B-cell leukaemias and lymphomas; progress and potential pitfalls

Regulation of CD38 in proliferating chronic lymphocytic leukemia cells stimulated with CD154 and interleukin-4.

STAT6-mediated BCL6 repression in primary mediastinal B-cell lymphoma (PMBL).

Separate cell culture conditions to promote proliferation or quiescent cell survival in chronic lymphocytic leukemia.

Similar patterns of V kappa gene usage but different degrees of somatic mutation in hairy cell leukemia, prolymphocytic leukemia, Waldenstrom's macroglobulinemia, and myeloma

Somatic hypermutation of Ig genes in patients with xeroderma pigmentosum (XP-D)

Somatic hypermutation of immunoglobulin genes

Specific patterns of chromosomal gains and losses associate with t(3;14), t(8;14), and t(14;18) in diffuse large B-cell lymphoma

Stromal cells and CD40 ligand (CD154) alter the miRNome and induce miRNA clusters including, miR-125b/miR-99a/let-7c and miR-17-92 in chronic lymphocytic leukaemia

Structural and diffusion weighted MRI demonstrates responses to ibrutinib in a mouse model of follicular helper (Tfh) T-cell lymphoma

Structure-function studies of an engineered scaffold protein derived from Stefin A. II: Development and applications of the SQT variant

Structure-function studies of an engineered scaffold protein derived from stefin A. I: Development of the SQM variant.

Suppression of signal transducer and activator of transcription 3-dependent B lymphocyte terminal differentiation by BCL-6.

TP53 codon 72 polymorphism in patients with chronic lymphocytic leukaemia: identification of a subgroup with mutated IGHV genes and poor clinical outcome

Targeting primary mediastinal B-cell lymphoma

The ansamycin antibiotic, rifamycin SV, inhibits BCL6 transcriptional repression and forms a complex with the BCL6-BTB/POZ domain

The diversity of antigen-specific monoclonal antibodies from transgenic mice bearing human immunoglobulin gene miniloci

The level of BCR-ABL1 kinase activity before treatment does not identify chronic myeloid leukemia patients who fail to achieve a complete cytogenetic response on imatinib

The new biology of PTCL-NOS and AITL: current status and future clinical impact

The role of BCL6 in lymphomas and routes to therapy

The targeting of somatic hypermutation

V kappa gene segments rearranged in chronic lymphocytic leukemia are distributed over a large portion of the V kappa locus and do not show somatic mutation

V lambda genes in chronic lymphocytic leukaemia: highly skewed V gene segment usage with similar CDR3 sequences

ZEB1 and CtBP form a repressive complex at a distal promoter element of the BCL6 locus

miR-125b and miR-155 contribute to BCL2 repression and proliferation in response to CD40 ligand (CD154) in human leukemic B-cells