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Lista de obras de Giuseppe Giaccone

"Pseudocavitation" in thymic carcinoma during treatment with sunitinib.

artículo científico publicado en 2013

10th Conference on DNA Topoisomerases in therapy

artículo científico publicado en 1999

18F-fluorodeoxyglucose positron emission tomography in the management of patients with thymic epithelial tumors

artículo científico publicado en 2013

18Fluorodeoxyglucose positron emission tomography, a standard diagnostic tool in lung cancer

artículo científico publicado en 2007

2011 Focused Update of 2009 American Society of Clinical Oncology Clinical Practice Guideline Update on Chemotherapy for Stage IV Non-Small-Cell Lung Cancer

artículo científico publicado en 2011

2011 Focused Update of 2009 American Society of Clinical Oncology Clinical Practice Guideline Update on Chemotherapy for Stage IV Non-Small-Cell Lung Cancer.

artículo científico publicado en 2011

4'-Deoxydoxorubicin, an inactive drug in small cell lung cancer

artículo científico publicado en 1987

4'-EPI-doxorubicin in advanced lung cancer. A phase II trial

artículo científico publicado en 1990

5-Fluorouracil induced Fas upregulation associated with apoptosis in liver metastases of colorectal cancer patients

artículo científico publicado en 2001

A PCR-aided transcript titration assay (PATTY) to measure topoisomerase I gene expression in human tumor specimens

artículo científico publicado en 1999

A Phase Ib/II Study of Ganetespib With Doxorubicin in Advanced Solid Tumors Including Relapsed-Refractory Small Cell Lung Cancer.

artículo científico publicado en 2018

A bone biopsy is mandatory in the optimal management of bone lesions in patients with a long-term history of malignancy of the breast

artículo científico publicado en 2000

A dose-finding and pharmacokinetic study of reversal of multidrug resistance with SDZ PSC 833 in combination with doxorubicin in patients with solid tumors.

artículo científico publicado en 1997

A parallel dose-escalation study of weekly and twice-weekly bortezomib in combination with gemcitabine and cisplatin in the first-line treatment of patients with advanced solid tumors

artículo científico publicado en 2007

A phase 2 trial of dacomitinib (PF-00299804), an oral, irreversible pan-HER (human epidermal growth factor receptor) inhibitor, in patients with advanced non-small cell lung cancer after failure of prior chemotherapy and erlotinib

artículo científico publicado en 2014

A phase I and pharmacokinetic study of LAF389 administered to patients with advanced cancer

artículo científico publicado en 2007

A phase I and pharmacokinetic study of gemcitabine given by 24-h hepatic arterial infusion

artículo científico publicado en 2009

A phase I combination study of olaparib with cisplatin and gemcitabine in adults with solid tumors.

artículo científico publicado en 2012

A phase I dose escalation study with anti-CD44v6 bivatuzumab mertansine in patients with incurable squamous cell carcinoma of the head and neck or esophagus

artículo científico publicado en 2006

A phase I pharmacologic study of necitumumab (IMC-11F8), a fully human IgG1 monoclonal antibody directed against EGFR in patients with advanced solid malignancies.

artículo científico publicado en 2010

A phase I safety and pharmacologic study of a twice weekly dosing regimen of the oral taxane BMS-275183

artículo científico publicado en 2007

A phase I study of PF-04929113 (SNX-5422), an orally bioavailable heat shock protein 90 inhibitor, in patients with refractory solid tumor malignancies and lymphomas

artículo científico publicado en 2011

A phase I study of intravenous artesunate in patients with advanced solid tumor malignancies

artículo científico publicado en 2018

A phase I study of sequential intravenous topotecan and etoposide in lung cancer patients

artículo científico publicado en 2001

A phase I study of the natural killer T-cell ligand alpha-galactosylceramide (KRN7000) in patients with solid tumors

artículo científico publicado en 2002

A phase I-II study of gemcitabine and paclitaxel in advanced non-small-cell lung cancer patients

scientific article published on 01 January 2000

A phase I/II study of pemetrexed with sirolimus in advanced, previously treated non-small cell lung cancer

scientific article published on 01 June 2019

A phase I/II study of sepantronium bromide (YM155, survivin suppressor) with paclitaxel and carboplatin in patients with advanced non-small-cell lung cancer.

artículo científico publicado en 2013

A phase I/II trial of belinostat in combination with cisplatin, doxorubicin, and cyclophosphamide in thymic epithelial tumors: a clinical and translational study.

artículo científico publicado en 2014

A phase II EORTC study of temozolomide in patients with malignant pleural mesothelioma

artículo científico publicado en 2002

A phase II study of YM155, a novel small-molecule suppressor of survivin, in castration-resistant taxane-pretreated prostate cancer

artículo científico publicado en 2011

A phase II study of active specific immunotherapy and 5-FU/Leucovorin as adjuvant therapy for stage III colon carcinoma

artículo científico publicado en 2002

A phase III study of belagenpumatucel-L, an allogeneic tumour cell vaccine, as maintenance therapy for non-small cell lung cancer.

artículo científico publicado en 2015

A population-based assessment of mortality and morbidity patterns among patients with thymoma

artículo científico publicado en 2010

A randomized study of high-dose split course radiotherapy preceded by high-dose chemotherapy versus high-dose radiotherapy only in locally advanced non-small-cell lung cancer. An EORTC Lung Cancer Cooperative Group trial

artículo científico publicado en 1996

A specific missense mutation in GTF2I occurs at high frequency in thymic epithelial tumors

artículo científico publicado en 2014

Accelerated cisplatin and high-dose epirubicin with G-CSF support in patients with relapsed non-small-cell lung cancer: feasibility and efficacy

artículo científico publicado en 2001

Acquired SETD2 mutation and impaired CREB1 activation confer cisplatin resistance in metastatic non-small cell lung cancer

scientific article published on 09 August 2018

Acquired small cell lung cancer resistance to Chk1 inhibitors involves Wee1 up-regulation

artículo científico publicado en 2020

Acute autoimmune hepatitis, myositis, and myasthenic crisis in a patient with thymoma.

artículo científico publicado en 2013

Adenoviral vector-mediated expression of a gene encoding secreted, EpCAM-targeted carboxylesterase-2 sensitises colon cancer spheroids to CPT-11

artículo científico publicado en 2005

Alterations of immune cell subsets in relapsed, thymoma-associated minimal change disease: A case report

artículo científico publicado en 2015

American Society of Clinical Oncology Clinical Practice Guideline Update on Chemotherapy for Stage IV Non-Small-Cell Lung Cancer

artículo científico publicado en 2010

American Society of Clinical Oncology Clinical Practice Guideline update on chemotherapy for stage IV non-small-cell lung cancer

artículo científico publicado en 2009

American Society of Clinical Oncology provisional clinical opinion: epidermal growth factor receptor (EGFR) Mutation testing for patients with advanced non-small-cell lung cancer considering first-line EGFR tyrosine kinase inhibitor therapy.

artículo científico publicado en 2011

An endogenous DNA adduct as a prognostic biomarker for hepatocarcinogenesis and its prevention by Theaphenon E in mice.

artículo científico publicado en 2017

An immune response enriched 72-gene prognostic profile for early-stage non-small-cell lung cancer

artículo científico publicado en 2009

Analysis of deoxycytidine accumulation in gemcitabine treated patients

artículo científico publicado en 2006

Angiogenesis inhibitors. Drug selectivity and target specificity.

artículo científico publicado en 2007

Anti-cytokine autoantibodies are associated with opportunistic infection in patients with thymic neoplasia

artículo científico publicado en 2010

Antiangiogenesis induced tumor cavitation in lung cancer

artículo científico publicado en 2009

Antiangiogenic therapy in nonsmall cell lung cancer.

artículo científico publicado en 2008

Antiproliferative activity of the topoisomerase I inhibitors topotecan and camptothecin, on sub- and postconfluent tumor cell cultures.

artículo científico publicado en 1994

Apoptosis: target of cancer therapy.

artículo científico publicado en 2002

Archival fine-needle aspiration cytopathology (FNAC) samples: untapped resource for clinical molecular profiling

artículo científico publicado en 2010

Are platinum compounds mandatory in the treatment of metastatic non-small cell lung cancer?

artículo científico publicado en 1998

Array comparative genomic hybridization-based characterization of genetic alterations in pulmonary neuroendocrine tumors.

artículo científico publicado en 2010

Assessment of IAP (inhibitor of apoptosis) proteins as predictors of response to chemotherapy in advanced non-small-cell lung cancer patients.

artículo científico publicado en 2001

Assessment of objective responses using volumetric evaluation in advanced thymic malignancies and metastatic non-small cell lung cancer

artículo científico publicado en 2011

Association of polymorphisms in AKT1 and EGFR with clinical outcome and toxicity in non-small cell lung cancer patients treated with gefitinib.

artículo científico publicado en 2010

Atezolizumab for First-Line Treatment of PD-L1-Selected Patients with NSCLC

scientific article published on 01 October 2020

Author's Reply

scientific article published on 01 October 2019

Automated serum peptide profiling using novel magnetic C18 beads off-line coupled to MALDI-TOF-MS

artículo científico publicado en 2007

Bepridil in combination with anthracyclines to reverse anthracycline resistance in cancer patients

artículo científico publicado en 1991

Bioanalysis, pharmacokinetics, and pharmacodynamics of the novel anticancer drug paclitaxel (Taxol).

artículo científico publicado en 1994

Biology and management of malignant pleural mesothelioma.

artículo científico publicado en 2006

Biomarkers in early-stage non-small-cell lung cancer: current concepts and future directions

artículo científico publicado en 2014

Biomarkers of response to epidermal growth factor receptor inhibitors in Non-Small-Cell Lung Cancer Working Group: standardization for use in the clinical trial setting.

artículo científico publicado en 2008

Bone marrow evaluation in small cell carcinoma of the lung

artículo científico publicado en 1987

Bortezomib induces schedule-dependent modulation of gemcitabine pharmacokinetics and pharmacodynamics in non-small cell lung cancer and blood mononuclear cells

artículo científico publicado en 2009

Bortezomib, but not cisplatin, induces mitochondria-dependent apoptosis accompanied by up-regulation of noxa in the non-small cell lung cancer cell line NCI-H460.

artículo científico publicado en 2007

Brain-only metastases of small cell lung cancer; efficacy of whole brain radiotherapy. An EORTC phase II study.

artículo científico publicado en 1998

Broad distribution of the multidrug resistance-related vault lung resistance protein in normal human tissues and tumors

artículo científico publicado en 1996

CPT-11 in human colon-cancer cell lines and xenografts: characterization of cellular sensitivity determinants

artículo científico publicado en 1997

CPT-11 sensitivity in relation to the expression of P170-glycoprotein and multidrug resistance-associated protein

artículo científico publicado en 1998

CRIPTO1 expression in EGFR-mutant NSCLC elicits intrinsic EGFR-inhibitor resistance.

artículo científico publicado en 2014

CRKL mediates EML4-ALK signaling and is a potential therapeutic target for ALK-rearranged lung adenocarcinoma

artículo científico publicado en 2016

CRM1-mediated nuclear export determines the cytoplasmic localization of the antiapoptotic protein Survivin

artículo científico publicado en 2002

CYB5A and autophagy-mediated cell death in pancreatic cancer

artículo científico publicado en 2014

Caelyx in malignant mesothelioma: a phase II EORTC study

artículo científico publicado en 2000

Cancer of the esophagus and gastric cardia: recent advances

artículo científico publicado en 2004

Capillary isoelectric-focusing immunoassays to study dynamic oncoprotein phosphorylation and drug response to targeted therapies in non-small cell lung cancer

artículo científico publicado en 2013

Carboplatin and paclitaxol (Taxol) as an induction regimen for patients with biopsy-proven stage IIIA N2 non-small cell lung cancer. an EORTC phase II study (EORTC 08958).

artículo científico publicado en 2003

Carboplatin dosage formulae can generate inaccurate predictions of Carboplatin exposure in carboplatin/paclitaxel combination regimens

artículo científico publicado en 1998

Case for Stopping Targeted Therapy When Lung Cancer Progresses on Treatment in Hospice-Eligible Patients

artículo científico publicado en 2017

Cathepsin B mediates caspase-independent cell death induced by microtubule stabilizing agents in non-small cell lung cancer cells.

artículo científico publicado en 2004

Cell cycle disturbances and apoptosis induced by topotecan and gemcitabine on human lung cancer cell lines.

artículo científico publicado en 1999

Cell death independent of caspases: a review.

artículo científico publicado en 2005

Challenges in cancer molecular targets and therapeutics.

artículo científico publicado en 2011

Characterization and management of cardiac involvement of thymic epithelial tumors

artículo científico publicado en 2013

Characterization of epidermal growth factor receptor mutations in non-small-cell lung cancer patients of African-American ancestry.

artículo científico publicado en 2010

Characterization of fibroblast growth factor receptor 1 in small-cell lung cancer.

artículo científico publicado en 2014

Characterization of human soft-tissue sarcoma xenografts for use in secondary drug screening

artículo científico publicado en 1998

Checkpoint Kinase 1 Inhibition Enhances Cisplatin Cytotoxicity and Overcomes Cisplatin Resistance in SCLC by Promoting Mitotic Cell Death

scientific article published on 14 February 2019

Chemosensitivity to the indoloquinone EO9 is correlated with DT-diaphorase activity and its gene expression

artículo científico publicado en 1994

Chemosensitizing tumor cells by targeting the Fanconi anemia pathway with an adenovirus overexpressing dominant-negative FANCA.

artículo científico publicado en 2004

Chemotherapy for thymic tumors: induction, consolidation, palliation

scientific article published on February 2011

Chemotherapy of a second instance of carcinoma of the ovary

scientific article published on 01 April 1984

Chemotherapy triggers apoptosis in a caspase-8-dependent and mitochondria-controlled manner in the non-small cell lung cancer cell line NCI-H460.

artículo científico publicado en 2000

Chest irradiation as an attempt to improve the response after induction chemotherapy in small cell lung carcinoma

artículo científico publicado en 1985

Circulating V(alpha24+) Vbeta11+ NKT cell numbers are decreased in a wide variety of diseases that are characterized by autoreactive tissue damage

artículo científico publicado en 2001

Circulating tumor DNA detection is correlated to histologic types in patients with early-stage non-small-cell lung cancer

artículo científico publicado en 2019

Cisplatin and etoposide combination chemotherapy for locally advanced or metastatic thymoma. A phase II study of the European Organization for Research and Treatment of Cancer Lung Cancer Cooperative Group

scientific article published on 01 March 1996

Cisplatin and teniposide chemotherapy for advanced non-small cell lung cancer

artículo científico publicado en 1991

Cisplatin triggers apoptotic or nonapoptotic cell death in Fanconi anemia lymphoblasts in a concentration-dependent manner.

artículo científico publicado en 2003

Cisplatin-containing chemotherapy in the treatment of invasive thymoma: report of five cases

Cisplatin/paclitaxel vs cisplatin/teniposide for advanced non-small-cell lung cancer. The EORTC Lung Cancer Cooperative Group. The European Organization for Research and Treatment of Cancer

artículo científico publicado en 1997

Cixutumumab for patients with recurrent or refractory advanced thymic epithelial tumours: a multicentre, open-label, phase 2 trial

artículo científico publicado en 2014

Clinical and pharmacologic study of multidrug resistance reversal with vinblastine and bepridil

scientific article published on 01 April 1994

Clinical pharmacology of carboplatin administered in combination with paclitaxel

artículo científico publicado en 1997

Clinical resistance to topoisomerase-targeted drugs.

artículo científico publicado en 1998

Combination of gemcitabine and cisplatin for advanced non-small cell lung cancer: a phase II study with emphasis on scheduling

artículo científico publicado en 2001

Combination therapy with gefitinib, an epidermal growth factor receptor tyrosine kinase inhibitor, gemcitabine and cisplatin in patients with advanced solid tumors

artículo científico publicado en 2004

Combined Pan-HER and ALK/ROS1/MET Inhibition with Dacomitinib and Crizotinib in Advanced Non-Small Cell Lung Cancer: Results of a Phase I Study

artículo científico publicado en 2016

Combined Small Cell Carcinoma of the Lung: Is It a Single Entity?

artículo científico publicado en 2017

Combined assessment of EGFR pathway-related molecular markers and prognosis of NSCLC patients

artículo científico publicado en 2008

Comparative proteomics analysis of caspase-9-protein complexes in untreated and cytochrome c/dATP stimulated lysates of NSCLC cells.

artículo científico publicado en 2008

Comparison of Eight Technologies to Determine Genotype at the UGT1A1 (TA)n Repeat Polymorphism: Potential Clinical Consequences of Genotyping Errors?

scientific article published on 30 January 2020

Comparison of methylprednisolone and metoclopramide in the prophylactic treatment of cis-platin-induced nausea and vomiting

artículo científico publicado en 1984

Comparison of two carboplatin-containing regimens with standard chemotherapy for small cell lung cancer in a randomised phase II study. The EORTC Lung Cancer Cooperative group

artículo científico publicado en 1992

Complete remission of metastatic colorectal cancer: a pitfall in a multidrug resistance reversal trial

scientific article published on 01 June 1994

Concurrent molecular alterations in tumors with germ line epidermal growth factor receptor T790M mutations.

artículo científico publicado en 2013

Continuous administration of irinotecan by hepatic arterial infusion: a phase I and pharmacokinetic study.

artículo científico publicado en 2002

Continuous infusion of hepatic arterial irinotecan in pretreated patients with colorectal cancer metastatic to the liver.

artículo científico publicado en 2004

Copy number aberrations of BCL2 and CDKN2A/B identified by array-CGH in thymic epithelial tumors.

artículo científico publicado en 2012

Copy number aberrations of genes regulating normal thymus development in thymic epithelial tumors.

artículo científico publicado en 2013

Cortisol is transported by the multidrug resistance gene product P-glycoprotein

artículo científico publicado en 1993

Cremophor EL pharmacokinetics in a phase I study of paclitaxel (Taxol) and carboplatin in non-small cell lung cancer patients

artículo científico publicado en 2000

Cross-resistance in the 2',2'-difluorodeoxycytidine (gemcitabine)-resistant human ovarian cancer cell line AG6000 to standard and investigational drugs

artículo científico publicado en 2000

Current chemotherapeutic possibilities in pancreaticobiliary cancer

artículo científico publicado en 1999

Cytotoxic effects of anticancer agents on subconfluent and multilayered postconfluent cultures

scientific article published on 01 January 1993

DNA copy number profiles correlate with outcome in colorectal cancer patients treated with fluoropyrimidine/antifolate-based regimens

artículo científico publicado en 2011

DT-diaphorase activity in normal and neoplastic human tissues; an indicator for sensitivity to bioreductive agents?

artículo científico publicado en 1995

DURABLE RESPONSE IN PATIENTS WITH THYMIC CARCINOMA TREATED WITH PEMBROLIZUMAB AFTER PROLONGED FOLLOW-UP

scientific article published on 25 November 2020

Dacomitinib, a new therapy for the treatment of non-small cell lung cancer

artículo científico

Dasatinib sensitises KRAS-mutant cancer cells to mitogen-activated protein kinase kinase inhibitor via inhibition of TAZ activity

scientific article published on 11 June 2018

Decline in the need for blood transfusions in cancer patients due to the use of epoietin alfa during cisplatin based chemotherapy

artículo científico publicado en 2001

Defective differentiation of myeloid and plasmacytoid dendritic cells in advanced cancer patients is not normalized by tyrosine kinase inhibition of the vascular endothelial growth factor receptor.

artículo científico publicado en 2007

Definitive and Adjuvant Radiotherapy in Locally Advanced Non-Small-Cell Lung Cancer: American Society of Clinical Oncology Clinical Practice Guideline Endorsement of the American Society for Radiation Oncology Evidence-Based Clinical Practice Guidel

artículo científico

Design and conduct of early clinical studies of immunotherapy agent combinations: recommendations from the task force on Methodology for the Development of Innovative Cancer Therapies

artículo científico publicado en 2018

Design and conduct of early clinical studies of two or more targeted anticancer therapies: recommendations from the task force on Methodology for the Development of Innovative Cancer Therapies

artículo científico publicado en 2013

Design and conduct of phase II studies of targeted anticancer therapy: recommendations from the task force on methodology for the development of innovative cancer therapies (MDICT)

artículo científico publicado en 2007

Detection and therapeutic implications of c-Met mutations in small cell lung cancer and neuroendocrine tumors

artículo científico publicado en 2013

Detection of cytokeratin-19 transcripts by reverse transcriptase-polymerase chain reaction in lung cancer cell lines and blood of lung cancer patients

artículo científico publicado el 1 de septiembre de 1997

Determinants of CPT-11 and SN-38 activities in human lung cancer cells

artículo científico publicado en 1998

Determination of PF-04928473 in human plasma using liquid chromatography with tandem mass spectrometry.

artículo científico publicado en 2010

Dexrazoxane in anthracycline extravasation

artículo científico publicado en 2000

Differential expression of DNA topoisomerases in non-small cell lung cancer and normal lung

artículo científico publicado en 1995

Differential expression of the c-kit proto-oncogene in germ cell tumours.

artículo científico publicado en 1995

Disorders of serum electrolytes and renal function in patients treated with cis-platinum on an outpatient basis

artículo científico publicado en 1985

Dithiolethione modified valproate and diclofenac increase E-cadherin expression and decrease proliferation of non-small cell lung cancer cells.

scientific article published on 23 July 2009

Docetaxel and cisplatin as induction chemotherapy in patients with pathologically-proven stage IIIA N2 non-small cell lung cancer: a phase II study of the European organization for research and treatment of cancer (EORTC 08984)

artículo científico publicado en 2006

Dose-finding and pharmacokinetic study of cisplatin, gemcitabine, and SU5416 in patients with solid tumors

artículo científico publicado en 2002

Dose-finding and sequencing study of paclitaxel and carboplatin in non-small cell lung cancer

artículo científico publicado en 1995

Dose-finding study of the multitargeted tyrosine kinase inhibitor SU6668 in patients with advanced malignancies

artículo científico publicado en 2005

Dose-intensive chemotherapy with doxorubicin, cyclophosphamide and GM-CSF fails to improve survival of metastatic breast cancer patients

artículo científico publicado en 1996

Downregulation of 18F-FDG uptake in PET as an early pharmacodynamic effect in treatment of non-small cell lung cancer with the mTOR inhibitor everolimus

artículo científico publicado en 2009

Downregulation of CYLD promotes IFN-γ mediated PD-L1 expression in thymic epithelial tumors

artículo científico publicado en 2020

Downstream molecular determinants of response to 5-fluorouracil and antifolate thymidylate synthase inhibitors.

artículo científico publicado en 2000

Doxorubicin and etoposide in the treatment of advanced measurable breast cancer

artículo científico publicado en 1990

Drug Resistance

artículo científico publicado en 1996

Drug development: portals of discovery

artículo científico publicado en 2012

Drug resistance-associated marker Lrp for prediction of response to chemotherapy and prognoses in advanced ovarian carcinoma.

artículo científico publicado en 1995

Drug-induced apoptosis in lung cnacer cells is not mediated by the Fas/FasL (CD95/APO1) signaling pathway.

artículo científico publicado en 2000

EGFR Mutations in Latinos From the United States and Latin America.

artículo científico publicado en 2016

EGFR and KRAS mutation analysis in cytologic samples of lung adenocarcinoma enabled by laser capture microdissection.

artículo científico publicado en 2011

EGFR point mutation confers resistance to gefitinib in a patient with non-small-cell lung cancer

artículo científico publicado en 2005

EMT is associated with, but does not drive resistance to ALK inhibitors among EML4-ALK non-small cell lung cancer

artículo científico publicado en 2015

Early Intervention with epoetin alfa during platinum-based chemotherapy: an analysis of quality-of-life results of a multicenter, randomized, controlled trial compared with population normative data.

artículo científico publicado en 2006

Early intervention with epoetin alfa during platinum-based chemotherapy: an analysis of the results of a multicenter, randomized, controlled trial based on initial hemoglobin level.

artículo científico publicado en 2006

Economic evaluation of antibiotic prophylaxis in small-cell lung cancer patients receiving chemotherapy: an EORTC double-blind placebo-controlled phase III study (08923).

artículo científico publicado en 2003

Effect of food on the pharmacokinetic behavior of the potent oral taxane BMS-275183.

artículo científico publicado en 2008

Effectiveness of intensive clinical and radiological follow-up in patients with surgically resected NSCLC. Analysis of 2661 patients from the prospective MAGRIT trial

artículo científico publicado en 2019

Effects of alpha-galactosylceramide (KRN7000), interleukin-12 and interleukin-7 on phenotype and cytokine profile of human Valpha24+ Vbeta11+ T cells

artículo científico publicado en 1999

Effects of early intervention with epoetin alfa on transfusion requirement, hemoglobin level and survival during platinum-based chemotherapy: Results of a multicenter randomised controlled trial.

artículo científico publicado en 2005

Effects of suramin on human lung cancer cell lines

artículo científico publicado en 1995

Effects of tubulin-inhibiting agents in human lung and breast cancer cell lines with different multidrug resistance phenotypes.

artículo científico publicado en 1998

Efficacy of everolimus (RAD001) in patients with advanced NSCLC previously treated with chemotherapy alone or with chemotherapy and EGFR inhibitors

artículo científico publicado en 2009

Emerging protein kinase inhibitors for non-small cell lung cancer

artículo científico

Endpoints and other considerations in phase I studies of targeted anticancer therapy: recommendations from the task force on Methodology for the Development of Innovative Cancer Therapies (MDICT)

artículo científico publicado en 2007

Enhanced cytotoxicity induced by gefitinib and specific inhibitors of the Ras or phosphatidyl inositol-3 kinase pathways in non-small cell lung cancer cells.

artículo científico publicado en 2006

Enhanced growth inhibition by combined DNA methylation/HDAC inhibitors in lung tumor cells with silenced CDKN2A.

artículo científico publicado en 2010

Epidermal growth factor receptor (EGFR) gene copy number detection in non-small-cell lung cancer; a comparison of fluorescence in situ hybridization and chromogenic in situ hybridization.

artículo científico publicado en 2007

Epidermal growth factor receptor expression analysis in chemotherapy-naive patients with advanced non-small-cell lung cancer treated with gefitinib or placebo in combination with platinum-based chemotherapy

artículo científico publicado en 2008

Epidermal growth factor receptor inhibitors in the treatment of non-small-cell lung cancer.

artículo científico publicado en 2005

Epidermal growth factor receptor mutations and gene amplification in non-small-cell lung cancer: molecular analysis of the IDEAL/INTACT gefitinib trials

artículo científico publicado en 2005

Epirubicin in malignant mesothelioma: a phase II study of the European Organization for Research and Treatment of Cancer Lung Cancer Cooperative Group

artículo científico publicado el 1 de mayo de 1992

Epirubicin in previously untreated patients with small cell lung cancer: a phase II study by the EORTC Lung Cancer Cooperative Group

artículo científico publicado en 1992

Epithelial tumors of the thymic gland are rare malignancies. Foreword

scientific article published on 01 October 2010

Erlotinib as maintenance treatment in advanced non-small-cell lung cancer: a multicentre, randomised, placebo-controlled phase 3 study.

artículo científico publicado en 2010

Erlotinib for frontline treatment of advanced non-small cell lung cancer: a phase II study

artículo científico publicado en 2006

Erlotinib versus docetaxel as second-line treatment of patients with advanced non-small-cell lung cancer and wild-type EGFR tumours (TAILOR): a randomised controlled trial

artículo científico publicado en 2013

Etoposide in malignant pleural mesothelioma: two phase II trials of the EORTC Lung Cancer Cooperative Group

scientific article published on 01 November 1997

Evaluation of KRAS mutations, angiogenic biomarkers, and DCE-MRI in patients with advanced non-small-cell lung cancer receiving sorafenib

artículo científico publicado en 2011

Evolutionarily conserved protein ERH controls CENP-E mRNA splicing and is required for the survival of KRAS mutant cancer cells

artículo científico publicado en 2012

Exercise-induced spontaneous hemothorax insinuates trauma; yet unmasks a lament disorder

artículo científico publicado en 2001

Expression and localization of inhibitor of apoptosis proteins in normal human tissues

artículo científico publicado en 2005

Expression and mutational status of c-kit in thymic epithelial tumors

artículo científico publicado en 2010

Expression of DNA topoisomerase IIalpha and topoisomerase IIbeta genes predicts survival and response to chemotherapy in patients with small cell lung cancer.

artículo científico publicado en 1999

Expression of X-linked inhibitor of apoptosis as a novel prognostic marker in radically resected non-small cell lung cancer patients

scientific article published on 01 August 2001

Expression of drug resistance proteins in breast cancer, in relation to chemotherapy

scientific article published on 01 May 1997

Expression of mesothelin in thymic carcinoma and its potential therapeutic significance

artículo científico publicado en 2016

Expression of the human major vault protein LRP in human lung cancer samples and normal lung tissues

artículo científico publicado en 1996

FANCD2 expression in advanced non-small-cell lung cancer and response to platinum-based chemotherapy.

artículo científico publicado en 2005

FOLFOX3 in heavily pretreated patients with metastatic colorectal cancer.

artículo científico publicado en 2004

Father-son testicular cancer, case report

scientific article published on 01 June 1983

Fluorouracil (5FU) pharmacokinetics in 5FU prodrug formulations with a dihydropyrimidine dehydrogenase inhibitor

artículo científico publicado en 2001

Follicular and epidermal alterations in patients treated with ZD1839 (Iressa), an inhibitor of the epidermal growth factor receptor

artículo científico publicado en 2002

Frequent overexpression of aurora B kinase, a novel drug target, in non-small cell lung carcinoma patients

artículo científico publicado en 2006

From targets to targeted therapies and molecular profiling in non-small cell lung carcinoma.

artículo científico publicado en 2012

Functional analysis of cancer-associated EGFR mutants using a cellular assay with YFP-tagged EGFR intracellular domain

artículo científico publicado en 2007

Ganetespib for small cell lung cancer

artículo científico publicado en 2016

Gefitinib in combination with gemcitabine and cisplatin in advanced non-small-cell lung cancer: a phase III trial--INTACT 1.

artículo científico publicado en 2004

Gefitinib in combination with paclitaxel and carboplatin in advanced non-small-cell lung cancer: a phase III trial--INTACT 2.

artículo científico publicado en 2004

Gemcitabine and paclitaxel combinations in non-small cell lung cancer

scientific article published on 01 August 1998

Gemcitabine and paclitaxel: pharmacokinetic and pharmacodynamic interactions in patients with non-small-cell lung cancer

scientific article published on 01 July 1999

Gemcitabine uptake in glioblastoma multiforme: potential as a radiosensitizer

artículo científico publicado en 2008

Gemcitabine-radiotherapy in patients with locally advanced pancreatic cancer.

artículo científico publicado en 2002

Genomic characteristics in Chinese non-small cell lung cancer patients and its value in prediction of postoperative prognosis

scientific article published on 01 August 2020

Genomic profiling of multiple sequentially acquired tumor metastatic sites from an "exceptional responder" lung adenocarcinoma patient reveals extensive genomic heterogeneity and novel somatic variants driving treatment response

artículo científico publicado en 2016

Genomics-based early-phase clinical trials in oncology: recommendations from the task force on Methodology for the Development of Innovative Cancer Therapies

scientific article published on 15 September 2014

Genotype analysis of the VNTR polymorphism in the SMYD3 histone methyltransferase gene: lack of correlation with the level of histone H3 methylation in NSCLC tissues or with the risk of NSCLC

scientific article published on 01 March 2008

Glioblastoma-induced inhibition of Langerhans cell differentiation from CD34(+) precursors is mediated by IL-6 but unaffected by JAK2/STAT3 inhibition

artículo científico publicado en 2011

Global histone modifications predict prognosis of resected non small-cell lung cancer.

artículo científico publicado en 2007

Glufosfamide administered by 1-hour infusion as a second-line treatment for advanced non-small cell lung cancer; a phase II trial of the EORTC-New Drug Development Group

artículo científico publicado en 2004

Growth, morphology and chemosensitivity studies on postconfluent cells cultured in 'V'-bottomed microtiter plates

artículo científico publicado en 1992

HER1/EGFR-targeted agents: predicting the future for patients with unpredictable outcomes to therapy.

artículo científico publicado en 2005

HER2 mutations in non-small-cell lung cancer can be continually targeted.

artículo científico publicado en 2012

HSP-90 inhibitor ganetespib is synergistic with doxorubicin in small cell lung cancer.

artículo científico publicado en 2013

Health economics: can we afford an unrestricted use of new biological agents in gastrointestinal oncology?

artículo científico publicado en 2005

Heat shock protein 90-sheltered overexpression of insulin-like growth factor 1 receptor contributes to malignancy of thymic epithelial tumors

artículo científico publicado en 2011

Hepatic arterial 5-fluorouracil in patients with liver metastases of colorectal cancer: single-centre experience in 145 patients

artículo científico publicado en 2000

Hepatic arterial chemotherapy for colorectal cancer metastatic to the liver

artículo científico publicado en 2000

Hepatoid carcinoma of the lung with anaplastic lymphoma kinase gene rearrangement.

artículo científico publicado en 2012

High cripto-1 and low miR-205 expression levels as prognostic markers in early stage non-small cell lung cancer

artículo científico publicado en 2017

High mesothelin expression in advanced lung adenocarcinoma is associated with KRAS mutations and a poor prognosis.

artículo científico publicado en 2015

Histone deacetylase inhibitors in cancer therapy

scientific article published on 01 November 2008

Homodimerization antagonizes nuclear export of survivin

artículo científico publicado en 2007

How should we analyse FDG PET studies for monitoring tumour response?

artículo científico publicado en 2006

Human natural killer T cells acquire a memory-activated phenotype before birth

artículo científico publicado en 2000

Hypertension and hand-foot skin reactions related to VEGFR2 genotype and improved clinical outcome following bevacizumab and sorafenib

artículo científico publicado en 2010

Identification of microRNA-21 as a biomarker for chemoresistance and clinical outcome following adjuvant therapy in resectable pancreatic cancer

artículo científico publicado en 2010

Identification of multiple nuclear export sequences in Fanconi anemia group A protein that contribute to CRM1-dependent nuclear export.

artículo científico publicado en 2005

Identification of new drugs in pretreated patients with small cell lung cancer

artículo científico publicado en 1989

Image microarrays (IMA): Digital pathology's missing tool

artículo científico publicado en 2011

Imatinib mesylate in patients with WHO B3 thymomas and thymic carcinomas.

artículo científico publicado en 2009

Immunocytochemical detection of deoxycytidine kinase in haematological malignancies and solid tumours

artículo científico publicado en 2005

Immunohistochemical detection of nuclear survivin in NSCLC: a comparison of commercial antibodies

artículo científico publicado en 2007

Impact of epidermal growth factor receptor and KRAS mutations on clinical outcomes in previously untreated non-small cell lung cancer patients: results of an online tumor registry of clinical trials

artículo científico publicado en 2009

Impact ofABCG2polymorphisms on the clinical outcome and toxicity of gefitinib in non-small-cell lung cancer patients

article

In vitro chemosensitivity testing of multilayered microcultures

artículo científico publicado el 1 de julio de 1992

In vitro evaluation of myelotoxicity induced by antineoplastic drugs

scientific article published on 01 June 1986

In vitro sequence-dependent synergistic effect of suramin and camptothecin.

artículo científico publicado en 1994

Inadequacy of the RECIST criteria for response evaluation in patients with malignant pleural mesothelioma

artículo científico publicado en 2004

Incorporating immune-checkpoint inhibitors into systemic therapy of NSCLC

artículo científico publicado en 2014

Increased expression of differentiation markers can accompany laminin-induced attachment of small cell lung cancer cells.

artículo científico publicado en 1992

Inhibition of AKT1 signaling promotes invasion and metastasis of non-small cell lung cancer cells with K-RAS or EGFR mutations

artículo científico

Insulin-like growth factor-1 receptor and phosphorylated AKT-serine 473 expression in 132 resected thymomas and thymic carcinomas

artículo científico publicado en 2010

International thymic malignancy interest group.

artículo científico publicado en 2010

Intrapulmonary lymph node retrieval: unclear benefit for aggressive pathologic dissection

artículo científico publicado en 2012

Introduction

artículo científico publicado en 2005

Iron absorption during epoetin alfa therapy for chemotherapy-associated anaemia

artículo científico publicado en 2006

Is a patient's self-reported health-related quality of life a prognostic factor for survival in non-small-cell lung cancer patients? A multivariate analysis of prognostic factors of EORTC study 08975

artículo científico publicado en 2006

Kahalalide F induces necrosis-like cell death that involves depletion of ErbB3 and inhibition of Akt signaling.

artículo científico publicado en 2005

Keynote comment: are large-scale cancer-genomics projects ready to use?

artículo científico publicado en 2006

LAMC2 enhances the metastatic potential of lung adenocarcinoma

artículo científico publicado en 2015

Late activation of apoptotic pathways plays a negligible role in mediating the cytotoxic effects of discodermolide and epothilone B in non-small cell lung cancer cells.

artículo científico publicado en 2002

Lessons learned from BATTLE-2 in the war on cancer: the use of Bayesian method in clinical trial design

artículo científico publicado en 2016

LncRNA H19 downregulation confers erlotinib resistance through upregulation of PKM2 and phosphorylation of AKT in EGFR-mutant lung cancers

artículo científico publicado en 2020

Long-term survival and complete response to adriamycin and etoposide in a case of hepatocellular carcinoma

artículo científico publicado en 1986

Long-term survival follow-up of atezolizumab in combination with platinum-based doublet chemotherapy in patients with advanced non-small-cell lung cancer

artículo científico publicado en 2018

Loss of 18q22.3 involving the carboxypeptidase of glutamate-like gene is associated with poor prognosis in resected pancreatic cancer

artículo científico publicado en 2011

Loss of p63 and its microRNA-205 target results in enhanced cell migration and metastasis in prostate cancer

artículo científico publicado en 2012

Lung cancer in 2013: Refining standard practice and admitting uncertainty

artículo científico

Lung cancer vaccines

artículo científico publicado en 2011

Lung cancer. Introduction

artículo científico publicado en 2003

Lung cancer: First-line immunotherapy in lung cancer - taking the first step

artículo científico publicado en 2016

MDR1/P-glycoprotein expression in colorectal cancer

artículo científico publicado en 1995

MEK inhibitors under development for treatment of non-small-cell lung cancer

artículo científico publicado en 2017

MRP gene overexpression in a human doxorubicin-resistant SCLC cell line: alterations in cellular pharmacokinetics and in pattern of cross-resistance.

artículo científico publicado en 1995

MRP is frequently expressed in human lung-cancer cell lines, in non-small-cell lung cancer and in normal lungs

scientific article published on 01 June 1996

Maintenance chemotherapy in small-cell lung cancer: long-term results of a randomized trial. European Organization for Research and Treatment of Cancer Lung Cancer Cooperative Group

artículo científico publicado en 1993

Met amplification and HSP90 inhibitors

artículo científico publicado en 2009

Metastatic lymphoepithelioma-like carcinoma of the lung treated with nivolumab: a case report and focused review of literature

artículo científico publicado en 2016

MicroRNA expression and clinical outcomes in patients treated with adjuvant chemotherapy after complete resection of non-small cell lung carcinoma

artículo científico publicado en 2010

Mitomycin C, teniposide, and cisplatin combination chemotherapy for advanced non-small-cell carcinoma of the lung

artículo científico publicado en 1991

Mitomycin C, vinblastine and cis-platin. An active regimen for advanced non-small cell lung cancer

artículo científico publicado en 1987

Mitoxantrone in malignant pleural mesothelioma: a study by the EORTC Lung Cancer Cooperative Group

artículo científico publicado en 1991

Molecular Pathways: Anticancer Activity by Inhibition of Nucleocytoplasmic Shuttling

artículo científico

Molecular Testing Guideline for Selection of Lung Cancer Patients for EGFR and ALK Tyrosine Kinase Inhibitors

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Molecular Testing Guideline for Selection of Lung Cancer Patients for EGFR and ALK Tyrosine Kinase Inhibitors: Guideline from the College of American Pathologists, International Association for the Study of Lung Cancer, and Association for Molecular

Molecular mechanisms underlying the synergistic interaction of erlotinib, an epidermal growth factor receptor tyrosine kinase inhibitor, with the multitargeted antifolate pemetrexed in non-small-cell lung cancer cells.

artículo científico publicado en 2008

Molecular profiling and targeted therapy for advanced thoracic malignancies: a biomarker-derived, multiarm, multihistology phase II basket trial

artículo científico publicado en 2015

Molecular testing guideline for selection of lung cancer patients for EGFR and ALK tyrosine kinase inhibitors

artículo científico publicado en 2013

Molecular testing guideline for selection of lung cancer patients for EGFR and ALK tyrosine kinase inhibitors: guideline from the College of American Pathologists, International Association for the Study of Lung Cancer, and Association for Molecular

artículo científico publicado en 2013

Morbidity and mortality in the surgery arm of EORTC 08941 trial

artículo científico publicado en 2005

Multi-institutional randomized phase II trial of gefitinib for previously treated patients with advanced non-small-cell lung cancer (The IDEAL 1 Trial) [corrected].

artículo científico publicado en 2003

Multicenter phase II trial of YM155, a small-molecule suppressor of survivin, in patients with advanced, refractory, non-small-cell lung cancer

artículo científico publicado en 2009

Multidrug resistance from the clinical point of view

artículo científico publicado en 1991

Multidrug resistance gene (P-glycoprotein) expression in the human fetus

artículo científico publicado el 1 de noviembre de 1992

Multidrug resistance in breast cancer: mechanisms, strategies.

artículo científico publicado en 1995

Multimodality treatment of malignant germ cell tumours of the mediastinum

artículo científico publicado el 1 de enero de 1991

Multiorgan autoimmune manifestations associated with thymoma.

artículo científico publicado en 2015

Multiple configurations of EGFR exon 20 resistance mutations after first- and third-generation EGFR TKI treatment affect treatment options in NSCLC

artículo científico publicado en 2018

Multiple cycles of high-dose doxorubicin and cyclophosphamide with G-CSF mobilized peripheral blood progenitor cell support in patients with metastatic breast cancer

artículo científico publicado en 1997

Mutant GTF2I induces cell transformation and metabolic alterations in thymic epithelial cells

artículo científico publicado en 2020

Mutations of epigenetic regulatory genes are common in thymic carcinomas

artículo científico publicado en 2014

NUT rearrangement is uncommon in human thymic epithelial tumors

artículo científico publicado en 2012

Natural Killer T cells

artículo científico publicado en 2002

Neuromedin B receptors regulate EGF receptor tyrosine phosphorylation in lung cancer cells.

artículo científico publicado en 2010

New drugs in non-small cell lung cancer. An overview

artículo científico publicado en 1995

Newer opportunities in systemic therapy of lung cancer

artículo científico publicado en 2008

Next generation oncology drug development: opportunities and challenges

artículo científico publicado en 2009

Next-Generation Sequencing: Targeting Targeted Therapies

artículo científico publicado en 2015

Novel Treatments for Thymoma and Thymic Carcinoma.

artículo científico publicado en 2015

Novel agents in the treatment of lung cancer: conference summary statement

artículo científico publicado en 2004

Novel approaches in cancer immunotherapy

artículo científico publicado en 2016

Novel approaches to the treatment of non-small cell lung cancer.

artículo científico publicado en 2002

Nuclear localization of survivin is a positive prognostic factor for survival in advanced non-small-cell lung cancer

scientific article published on 01 November 2004

Nuclear shuttling and TRAF2-mediated retention in the cytoplasm regulate the subcellular localization of cIAP1 and cIAP2.

artículo científico publicado en 2004

Oncogenic drivers, targeted therapies, and acquired resistance in non-small-cell lung cancer

artículo científico

Oncolytic activity of p53-expressing conditionally replicative adenovirus AdDelta24-p53 against human malignant glioma

artículo científico publicado en 2004

Ongoing and future trials of biologic therapies in lung cancer.

artículo científico publicado en 2003

Ongoing clinical trials in lung cancer.

artículo científico publicado en 1996

Oral ifosfamide/mesna versus intravenous ifosfamide/mesna in non-small-cell lung cancer: a randomized phase II trial of the EORTC lung cancer cooperative group

artículo científico publicado en 1996

Overexpression of Bcl2 abrogates chemo- and radiotherapy-induced sensitisation of NCI-H460 non-small-cell lung cancer cells to adenovirus-mediated expression of full-length TRAIL.

artículo científico publicado en 2004

P-glycoprotein--a marker of cancer-cell behavior

scientific article published on 01 November 1995

PI3K as a Potential Therapeutic Target in Thymic Epithelial Tumors

artículo científico publicado en 2016

Paclitaxel for malignant pleural mesothelioma: a phase II study of the EORTC Lung Cancer Cooperative Group

artículo científico publicado en 1996

Paclitaxel triggers cell death primarily via caspase-independent routes in the non-small cell lung cancer cell line NCI-H460.

artículo científico publicado en 2002

Pancreaticobiliary cancer: the future aspects of medical oncology

artículo científico publicado en 1999

Pembrolizumab in patients with thymic carcinoma: a single-arm, single-centre, phase 2 study

artículo científico publicado en 2018

Personalizing therapy in an epidermal growth factor receptor-tyrosine kinase inhibitor-resistant non-small-cell lung cancer using PF-00299804 and trastuzumab

artículo científico publicado en 2010

Pharmacokinetics of S-1, an oral formulation of ftorafur, oxonic acid and 5-chloro-2,4-dihydroxypyridine (molar ratio 1:0.4:1) in patients with solid tumors

artículo científico publicado en 2003

Pharmacokinetics of paclitaxel and carboplatin in a dose-escalating and dose-sequencing study in patients with non-small-cell lung cancer. The European Cancer Centre

artículo científico publicado en 1997

Pharmacological aspects of the enzastaurin-pemetrexed combination in non-small cell lung cancer (NSCLC).

artículo científico publicado en 2010

Pharmacology of the paclitaxel-cisplatin, gemcitabine-cisplatin, and paclitaxel-gemcitabine combinations in patients with advanced non-small cell lung cancer.

artículo científico publicado en 2006

Phase 0 clinical trials: recommendations from the Task Force on Methodology for the Development of Innovative Cancer Therapies

artículo científico publicado en 2008

Phase I and pharmacokinetic study of the novel chemoprotector BNP7787 in combination with cisplatin and attempt to eliminate the hydration schedule.

artículo científico publicado en 2005

Phase I clinical and pharmacokinetic study of oral S-1 in patients with advanced solid tumors

artículo científico publicado en 2000

Phase I evaluation of cediranib, a selective VEGFR signalling inhibitor, in combination with gefitinib in patients with advanced tumours

artículo científico publicado en 2010

Phase I study of the 177Lu-DOTA0-Tyr3-Octreotate (lutathera) in combination with nivolumab in patients with neuroendocrine tumors of the lung

artículo científico publicado en 2020

Phase I trial of 17-dimethylaminoethylamino-17-demethoxygeldanamycin (17-DMAG), a heat shock protein inhibitor, administered twice weekly in patients with advanced malignancies

artículo científico publicado en 2010

Phase I trial of SU14813 in patients with advanced solid malignancies.

artículo científico publicado en 2010

Phase I trial of belinostat with cisplatin and etoposide in advanced solid tumors, with a focus on neuroendocrine and small cell cancers of the lung.

artículo científico publicado en 2018

Phase I trial with BMS-275183, a novel oral taxane with promising antitumor activity

scientific article published on 01 March 2006

Phase II study of 9-hydroxy-2-methyl-ellipticinium acetate (ellipticinium) in patients with advanced carcinoma of the lung. EORTC Lung Cancer Cooperative Group

artículo científico publicado en 1989

Phase II study of ACNU as second-line treatment in small-cell lung cancer. EORTC Lung Cancer Cooperative Group

artículo científico publicado en 1992

Phase II study of ACNU in non-small-cell lung cancer: EORTC study 08872.

artículo científico publicado en 1991

Phase II study of alpha-interferon plus bleomycin in advanced non-small cell lung cancer

artículo científico publicado en 1989

Phase II study of belinostat in patients with recurrent or refractory advanced thymic epithelial tumors

artículo científico publicado en 2011

Phase II study of cisplatin preceding gemcitabine in patients with advanced oesophageal cancer

artículo científico publicado en 2004

Phase II study of divided-dose vinblastine in advanced breast cancer patients

artículo científico publicado en 1988

Phase II study of divided-dose vinblastine in advanced cancer patients

artículo científico publicado en 1989

Phase II study of esorubicin in the treatment of patients with advanced sarcoma

artículo científico publicado en 1989

Phase II study of single-agent navitoclax (ABT-263) and biomarker correlates in patients with relapsed small cell lung cancer

artículo científico publicado en 2012

Phase II study of tailored chemotherapy for advanced colorectal cancer with either 5-fluouracil and leucovorin or oxaliplatin and irinotecan based on the expression of thymidylate synthase and dihydropyrimidine dehydrogenase

artículo científico publicado en 2005

Phase II trial of cisplatin and gemcitabine in patients with advanced gastric cancer.

artículo científico publicado en 2004

Phase III study of adjuvant vaccination with Bec2/bacille Calmette-Guerin in responding patients with limited-disease small-cell lung cancer (European Organisation for Research and Treatment of Cancer 08971-08971B; Silva Study).

artículo científico publicado en 2005

Phase Ib safety and pharmacokinetic evaluation of daily and twice daily oral enzastaurin in combination with pemetrexed in advanced/metastatic cancer.

artículo científico publicado en 2009

Pilot study of teniposide in combination chemotherapy for small cell lung cancer

scientific article published on 01 January 1991

Piperacillin and amikacin in the treatment of infections in neoplasm patients with granulocytopenia

artículo científico publicado en 1989

Plantar erythrodysesthesia with bullous otitis externa, toxicities from sorafenib: a case report

artículo científico publicado en 2009

Plantar erythrodysesthesia with bullous otitis externa, toxicities from sorafenib: a case report

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Polarization of Valpha24+ Vbeta11+ natural killer T cells of healthy volunteers and cancer patients using alpha-galactosylceramide-loaded and environmentally instructed dendritic cells

scientific article published on 01 July 2003

Population pharmacokinetic analysis of sorafenib in patients with solid tumours.

artículo científico publicado en 2011

Population pharmacokinetics of the novel anticancer agent KRN7000.

artículo científico publicado en 2002

Potent expansion of human natural killer T cells using alpha-galactosylceramide (KRN7000)-loaded monocyte-derived dendritic cells, cultured in the presence of IL-7 and IL-15

scientific article published on 01 January 2001

Precision oncology in non-small-cell lung cancer: opportunities and challenges

artículo científico publicado en 2018

Prediction of outcome of non-small cell lung cancer patients treated with chemotherapy and bortezomib by time-course MALDI-TOF-MS serum peptide profiling

artículo científico publicado en 2009

Predictive factors for outcome in a phase II study of gefitinib in second-line treatment of advanced esophageal cancer patients.

artículo científico publicado en 2006

Preliminary results of two dose-finding studies of paclitaxel (Taxol) and carboplatin in non-small cell lung and ovarian cancers: a European Cancer Centre effort

artículo científico publicado en 1994

Prognostic factors in patients with pleural mesothelioma: the European Organization for Research and Treatment of Cancer experience

artículo científico publicado en 1998

Prognostic value of the expression of p53, bcl-2, and bax oncoproteins, and neovascularization in patients with radically resected non-small-cell lung cancer

artículo científico publicado en 1997

Prolonged neoadjuvant chemotherapy with GM-CSF in locally advanced breast cancer

artículo científico publicado en 1999

Prospective, randomized, double-blind, placebo-controlled trial of marimastat after response to first-line chemotherapy in patients with small-cell lung cancer: a trial of the National Cancer Institute of Canada-Clinical Trials Group and the Europea

artículo científico publicado en 2002

Quality assurance of thoracic radiotherapy in EORTC 08941: a randomised trial of surgery versus thoracic radiotherapy in patients with stage IIIA non-small-cell lung cancer (NSCLC) after response to induction chemotherapy

artículo científico publicado en 2006

Quantitative PET imaging of Met-expressing human cancer xenografts with 89Zr-labelled monoclonal antibody DN30.

artículo científico publicado en 2008

Radiotherapy with/without cisplatin following chemotherapy in limited small-cell lung cancer

artículo científico publicado en 1998

Randomised phase 2 study of pembrolizumab plus CC-486 versus pembrolizumab plus placebo in patients with previously treated advanced non-small cell lung cancer

artículo científico publicado en 2019

Randomised trial of sequential versus concurrent chemo-radiotherapy in patients with inoperable non-small cell lung cancer (EORTC 08972-22973)

scientific article published on 03 November 2006

Randomized controlled trial of resection versus radiotherapy after induction chemotherapy in stage IIIA-N2 non-small-cell lung cancer.

artículo científico publicado en 2007

Randomized phase 2 study of gemcitabine and cisplatin with or without vitamin supplementation in patients with advanced esophagogastric cancer.

artículo científico publicado en 2018

Randomized phase III study of cisplatin with or without raltitrexed in patients with malignant pleural mesothelioma: an intergroup study of the European Organisation for Research and Treatment of Cancer Lung Cancer Group and the National Cancer Inst

artículo científico publicado en 2005

Randomized trial of alternating versus sequential radiotherapy/chemotherapy in limited-disease patients with small-cell lung cancer: a European Organization for Research and Treatment of Cancer Lung Cancer Cooperative Group Study

artículo científico publicado el 1 de agosto de 1997

Recombinant human endostatin administered as a 28-day continuous intravenous infusion, followed by daily subcutaneous injections: a phase I and pharmacokinetic study in patients with advanced cancer

scientific article published on 12 July 2005

Reduction of chemotherapy-induced febrile leucopenia by prophylactic use of ciprofloxacin and roxithromycin in small-cell lung cancer patients: an EORTC double-blind placebo-controlled phase III study.

artículo científico publicado en 2001

Refining the treatment of NSCLC according to histological and molecular subtypes

artículo científico

Reinduction chemotherapy in small cell lung cancer

artículo científico publicado en 1987

Reply to A. Stenzinger et al

artículo científico publicado en 2015

Reprint of: Circulating cell-free DNA mutation patterns in early and late stage colon and pancreatic cancer

artículo científico publicado en 2018

Reproducibility of pharmacogenetics findings for paclitaxel in a heterogeneous population of patients with lung cancer

artículo científico publicado en 2019

Reproducibility of the WHO classification of thymomas: practical implications

artículo científico publicado en 2012

Response to crizotinib in ROS1-rearranged non-small-cell lung cancer.

artículo científico publicado en 2012

Response to epidermal growth factor receptor inhibitors in non-small cell lung cancer cells: limited antiproliferative effects and absence of apoptosis associated with persistent activity of extracellular signal-regulated kinase or Akt kinase pathwa

artículo científico publicado en 2003

Response to: intrapulmonary lymph node retrieval.

artículo científico publicado en 2013

Results of the phase II EORTC study comparing paclitaxel/cisplatin with teniposide/cisplatin in patients with non-small cell lung cancer. EORTC Lung Cancer Cooperative Group

scientific article published on 01 October 1996

Role and relevance of TrkB mutations and expression in non-small cell lung cancer

artículo científico publicado en 2011

Role of CYB5A in pancreatic cancer prognosis and autophagy modulation

artículo científico publicado en 2013

Role of XIAP in inhibiting cisplatin-induced caspase activation in non-small cell lung cancer cells: a small molecule Smac mimic sensitizes for chemotherapy-induced apoptosis by enhancing caspase-3 activation.

artículo científico publicado en 2006

Role of cMET expression in non-small-cell lung cancer patients treated with EGFR tyrosine kinase inhibitors

artículo científico publicado en 2008

Role of recombinant interferon-gamma maintenance in responding patients with small cell lung cancer. A randomised phase III study of the EORTC Lung Cancer Cooperative Group

scientific article published on 01 October 1997

STA-9090, a small-molecule Hsp90 inhibitor for the potential treatment of cancer

artículo científico publicado el 1 de diciembre de 2010

Schedule-dependent pharmacodynamic effects of gemcitabine and cisplatin in mice bearing Lewis lung murine non-small cell lung tumours

scientific article published on 01 December 2000

Schedule-dependent synergy of histone deacetylase inhibitors with DNA damaging agents in small cell lung cancer

artículo científico publicado en 2011

Second-line chemotherapy and its evaluation in small cell lung cancer

artículo científico publicado en 1999

Second-line chemotherapy in relapsing or refractory non-small-cell lung cancer: a review

artículo científico publicado en 2000

Selective decrease in circulating V alpha 24+V beta 11+ NKT cells during HIV type 1 infection

artículo científico publicado en 2002

Selumetinib with and without erlotinib in KRAS mutant and KRAS wild-type advanced nonsmall-cell lung cancer.

artículo científico publicado en 2016

Semiautomated laser capture microdissection of lung adenocarcinoma cytology samples.

artículo científico publicado en 2012

Sensitivity and kinase activity of epidermal growth factor receptor (EGFR) exon 19 and others to EGFR-tyrosine kinase inhibitors

artículo científico publicado en 2013

Sequence dependent effect of paclitaxel on gemcitabine metabolism in relation to cell cycle and cytotoxicity in non-small-cell lung cancer cell lines.

artículo científico publicado en 2000

Severe acute lung injury induced by gemcitabine.

artículo científico publicado en 2000

Severe reversible cardiac failure after bortezomib treatment combined with chemotherapy in a non-small cell lung cancer patient: a case report

artículo científico publicado en 2006

Short-term treatment-related symptoms and quality of life: results from an international randomized phase III study of cisplatin with or without raltitrexed in patients with malignant pleural mesothelioma: an EORTC Lung-Cancer Group and National Can

artículo científico publicado en 2006

Signal transduction modulators for cancer therapy: from promise to practice?

artículo científico publicado en 2003

Skin tests predict survival after autologous tumor cell vaccination in metastatic melanoma: experience in 81 patients

scientific article published on 01 August 2000

Small Cell Lung Cancer: Can Recent Advances in Biology and Molecular Biology Be Translated into Improved Outcomes?

artículo científico publicado en 2016

Small-molecule inhibitors of the human epidermal receptor family.

scientific article published on December 2009

Sorafenib is an inhibitor of UGT1A1 but is metabolized by UGT1A9: implications of genetic variants on pharmacokinetics and hyperbilirubinemia.

artículo científico publicado en 2012

Spisulosine (ES-285) given as a weekly three-hour intravenous infusion: results of a phase I dose-escalating study in patients with advanced solid malignancies

artículo científico publicado en 2011

Src as a potential therapeutic target in non-small-cell lung cancer.

artículo científico publicado en 2008

Standard versus alternating non-cross-resistant chemotherapy in extensive small cell lung cancer: an EORTC Phase III trial

scientific article published on 01 August 1996

Standard versus intensified chemotherapy with granulocyte colony-stimulating factor support in small-cell lung cancer: a prospective European Organization for Research and Treatment of Cancer-Lung Cancer Group Phase III Trial-08923.

artículo científico publicado en 2002

Strategies for overcoming resistance to EGFR family tyrosine kinase inhibitors

artículo científico publicado en 2011

Subcellular localization and nucleocytoplasmic transport of the chromosomal passenger proteins before nuclear envelope breakdown

artículo científico publicado en 2006

Subcellular localization of CrmA: identification of a novel leucine-rich nuclear export signal conserved in anti-apoptotic serpins.

artículo científico publicado en 2003

Sunitinib in patients with chemotherapy-refractory thymoma and thymic carcinoma: an open-label phase 2 trial.

artículo científico publicado en 2015

Sunitinib-induced myeloid lineage redistribution in renal cell cancer patients: CD1c+ dendritic cell frequency predicts progression-free survival

artículo científico publicado en 2008

Surgical Resection of SCLC: Prognostic Factors and the Tumor Microenvironment

scientific article published on 05 February 2019

Survival benefit with erlotinib maintenance therapy in patients with advanced non-small-cell lung cancer (NSCLC) according to response to first-line chemotherapy.

artículo científico publicado en 2011

Symptom and quality of life results of an international randomised phase III study of adjuvant vaccination with Bec2/BCG in responding patients with limited disease small-cell lung cancer

artículo científico publicado en 2008

Synergistic effect of KRN7000 with interleukin-15, -7, and -2 on the expansion of human V alpha 24+V beta 11+ T cells in vitro

artículo científico publicado en 2000

Systemic Therapy for Stage IV Non-Small-Cell Lung Cancer: American Society of Clinical Oncology Clinical Practice Guideline Update

artículo científico publicado en 2015

Systemic therapy, clinical outcomes, and overall survival in locally advanced or metastatic pulmonary carcinoid: a brief report.

artículo científico publicado en 2014

TPP1 OB-fold domain protein suppresses cell proliferation and induces cell apoptosis by inhibiting telomerase recruitment to telomeres in human lung cancer cells

scientific article published on 23 April 2019

TRAIL therapy in non-small cell lung cancer cells: sensitization to death receptor-mediated apoptosis by proteasome inhibitor bortezomib.

artículo científico publicado en 2007

TUCAN/CARDINAL/CARD8 and apoptosis resistance in non-small cell lung cancer cells

artículo científico publicado en 2006

TWO SUDDEN DEATHS DURING PROPHYLACTIC ANTIEMETIC TREATMENT WITH HIGH DOSES OF DOMPERIDONE AND METHYLPREDNISOLONE

artículo científico publicado en 1984

Talactoferrin alfa versus placebo in patients with refractory advanced non-small-cell lung cancer (FORTIS-M trial).

artículo científico publicado en 2013

Targeted agents: how to select the winners in preclinical and early clinical studies?

artículo científico publicado en 2011

Targeted therapies: Importance of patient selection for EGFR TKIs in lung cancer

artículo científico publicado en 2010

Targeted therapy for advanced thymic tumors

artículo científico publicado en 2010

Targeting HER1/EGFR in cancer therapy: experience with erlotinib

artículo científico publicado en 2005

Targeting HER2 aberrations as actionable drivers in lung cancers: phase II trial of the pan-HER tyrosine kinase inhibitor dacomitinib in patients with HER2-mutant or amplified tumors

artículo científico publicado en 2015

Targeting the dynamic HSP90 complex in cancer

artículo científico publicado en 2010

Targeting the epigenome in lung cancer: expanding approaches to epigenetic therapy

artículo científico publicado en 2013

Targeting the immune system in non-small-cell lung cancer: bridging the gap between promising concept and therapeutic reality

artículo científico publicado en 2010

Temozolomide in patients with advanced non-small cell lung cancer with and without brain metastases. a phase II study of the EORTC Lung Cancer Group (08965).

artículo científico publicado en 2003

Teniposide (VM26): an effective treatment for brain metastases of small cell carcinoma of the lung

artículo científico publicado en 1988

Teniposide for brain metastases of small-cell lung cancer: a phase II study. European Organization for Research and Treatment of Cancer Lung Cancer Cooperative Group

artículo científico publicado en 1995

Teniposide in the treatment of non-small cell lung carcinoma

artículo científico publicado en 1987

The GYMSSA trial: a prospective randomized trial comparing gastrectomy, metastasectomy plus systemic therapy versus systemic therapy alone

artículo científico publicado en 2009

The IASLC Lung Cancer Staging Project: Proposals for Revision of the TNM Stage Groupings in the Forthcoming (Eighth) Edition of the TNM Classification for Lung Cancer

article

The IASLC/ITMIG Thymic Epithelial Tumors Staging Project: proposal for an evidence-based stage classification system for the forthcoming (8th) edition of the TNM classification of malignant tumors.

artículo científico publicado en 2014

The IASLC/ITMIG Thymic Epithelial Tumors Staging Project: proposals for the N and M components for the forthcoming (8th) edition of the TNM classification of malignant tumors

artículo científico publicado en 2014

The IASLC/ITMIG Thymic Epithelial Tumors Staging Project: proposals for the T Component for the forthcoming (8th) edition of the TNM classification of malignant tumors

artículo científico publicado en 2014

The IASLC/ITMIG thymic malignancies staging project: development of a stage classification for thymic malignancies.

artículo científico publicado en 2013

The ITMIG/IASLC Thymic Epithelial Tumors Staging Project: A Proposed Lymph Node Map for Thymic Epithelial Tumors in the Forthcoming 8th Edition of the TNM Classification of Malignant Tumors

artículo científico publicado en 2014

The Integrated Genomic Landscape of Thymic Epithelial Tumors

artículo científico publicado en 2018

The International Association for the Study of Lung Cancer Lung Cancer Staging Project: Proposals for the Revision of the Clinical and Pathologic Staging of Small Cell Lung Cancer in the Forthcoming Eighth Edition of the TNM Classification for Lung C

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The International Association for the Study of Lung Cancer Thymic Tumors Staging Project: The Impact of the Eighth Edition of the Union for International Cancer Control and American Joint Committee on Cancer TNM Stage Classification of Thymic Tumors

scientific article published on 27 November 2019

The Janus kinases inhibitor AZD1480 attenuates growth of small cell lung cancers in vitro and in vivo

artículo científico publicado en 2013

The activity of raltitrexed (Tomudex) in malignant pleural mesothelioma: an EORTC phase II study (08992)

artículo científico publicado en 2003

The apoptotic pathway triggered by the Fhit protein in lung cancer cell lines is not affected by Bcl-2 or Bcl-x(L) overexpression

artículo científico publicado en 2004

The determination of gemcitabine and 2'-deoxycytidine in human plasma and tissue by APCI tandem mass spectrometry

artículo científico publicado en 2006

The differential diagnosis of primary lung cancer: inter-observer agreement and contribution of specific diagnostic procedures

artículo científico publicado en 1992

The effect of food on the pharmacokinetics of S-1 after single oral administration to patients with solid tumors

artículo científico publicado en 2004

The epidermal growth factor receptor pathway and its inhibition as anticancer therapy.

artículo científico publicado en 2003

The expression of TUCAN, an inhibitor of apoptosis protein, in patients with advanced non-small cell lung cancer treated with chemotherapy

scientific article published on 01 September 2006

The immunoregulatory role of CD1d-restricted natural killer T cells in disease.

artículo científico publicado en 2004

The multilayered postconfluent cell culture as a model for drug screening

artículo científico publicado en 2000

The potential of antiangiogenic therapy in non-small cell lung cancer.

artículo científico publicado en 2007

The proteasomal and apoptotic phenotype determine bortezomib sensitivity of non-small cell lung cancer cells.

artículo científico publicado en 2007

The role of EGFR-TK inhibition in non-small cell lung cancer

artículo científico publicado en 2005

The role of KRAS mutations in resistance to EGFR inhibition in the treatment of cancer.

artículo científico publicado en 2009

The role of gefitinib in lung cancer treatment.

artículo científico publicado en 2004

The role of new agents in the treatment of non-small cell lung cancer.

artículo científico publicado en 2002

The role of talactoferrin alpha in the treatment of non-small cell lung cancer.

scientific article published on September 2010

The use of perfusion CT for the evaluation of therapy combining AZD2171 with gefitinib in cancer patients

artículo científico publicado en 2006

Therapeutic Effects of XPO1 Inhibition in Thymic Epithelial Tumors

artículo científico publicado en 2017

Three-arm randomized study of two cisplatin-based regimens and paclitaxel plus gemcitabine in advanced non-small-cell lung cancer: a phase III trial of the European Organization for Research and Treatment of Cancer Lung Cancer Group--EORTC 08975.

artículo científico publicado en 2003

Thymic epithelial tumors: From biology to treatment

scientific article published on 23 March 2020

Thymic malignancies: from clinical management to targeted therapies

artículo científico publicado en 2011

Thymoma-associated paraneoplastic polymyositis

artículo científico publicado en 2010

Thymoma: update for the new millennium.

artículo científico publicado en 2001

Thymomas. A review of 169 cases, with particular reference to results of surgical treatment

artículo científico publicado en 1986

Thymomas: the need for prospective studies.

artículo científico publicado en 2013

Tissue micro array analysis of ganglioside N-glycolyl GM3 expression and signal transducer and activator of transcription (STAT)-3 activation in relation to dendritic cell infiltration and microvessel density in non-small cell lung cancer

artículo científico publicado en 2009

Topoisomerase IIalpha and other drug resistance markers in advanced non-small cell lung cancer

artículo científico publicado en 2001

Topotecan, a new active drug in the second-line treatment of small-cell lung cancer: a phase II study in patients with refractory and sensitive disease. The European Organization for Research and Treatment of Cancer Early Clinical Studies Group and

scientific article published on 01 May 1997

Treatment of Small-Cell Lung Cancer: American Society of Clinical Oncology Endorsement of the American College of Chest Physicians Guideline

artículo científico publicado en 2016

Treatment of Small-Cell Lung Cancer: American Society of Clinical Oncology Endorsement of the American College of Chest Physicians Guideline

artículo científico publicado en 2015

Treatment of advanced thymoma and thymic carcinoma.

scientific article published on December 2008

Treatment of brain metastases of small-cell lung cancer: comparing teniposide and teniposide with whole-brain radiotherapy--a phase III study of the European Organization for the Research and Treatment of Cancer Lung Cancer Cooperative Group

scientific article published on 01 October 2000

Treatment of malignant thymoma.

artículo científico publicado en 2005

Treatment of nonsmall cell lung cancer: overcoming the resistance to epidermal growth factor receptor inhibitors

artículo científico publicado en 2012

Trends and Characteristics of Young Non-Small Cell Lung Cancer Patients in the United States

artículo científico publicado en 2015

Tumor-intrinsic and tumor-extrinsic factors impacting hsp90- targeted therapy

artículo científico publicado en 2012

Two schedules of teniposide with or without cisplatin in advanced non-small-cell lung cancer: a randomized study of the European Organization for Research and Treatment of Cancer Lung Cancer Cooperative Group

scientific article published on 01 January 1996

Tyrosine kinase inhibitors in lung cancer

artículo científico publicado en 2012

Uncoupling the central spindle-associated function of the chromosomal passenger complex from its role at centromeres

artículo científico publicado en 2006

Understanding molecular diagnostic technology in oncology through the lens of lung cancer

scientific article published on 01 August 2018

Update on Hsp90 inhibitors in clinical trial.

artículo científico publicado en 2009

Validation of a polymerase chain reaction aided transcript titration assay (PATTY) for topoisomerase II in lung cancer samples

scientific article published on 01 September 2000

Why has active immunotherapy not worked in lung cancer?

artículo científico publicado en 2015

[American Society of Clinical Oncology Clinical Practice Guideline update on chemotherapy for stage IV non-small-cell lung cancer]

artículo científico publicado en 2010

[Chemotherapy in advanced forms of carcinoma of the ovary]

artículo científico publicado en 1984

[Monitoring of neuron specific enolase (NSE) in patients with a diagnosis of pulmonary microcytoma. Preliminary results]

scientific article published on 01 October 1987

p53 and P-glycoprotein are often co-expressed and are associated with poor prognosis in breast cancer

artículo científico publicado en 1996

p53 and chemosensitivity.

artículo científico publicado en 1999