Filtros de búsqueda

Lista de obras de Thomas Knöpfel

A comprehensive concept of optogenetics

artículo científico publicado en 2012

Activation of cerebellar parallel fibers monitored in transgenic mice expressing a fluorescent Ca2+ indicator protein.

artículo científico publicado en 2005

Activation of metabotropic glutamate receptors coupled to inositol phospholipid hydrolysis amplifies NMDA-induced neuronal degeneration in cultured cortical cells

artículo científico publicado en 1995

Activation of metabotropic glutamate receptors induces an outward current which is potentiated by methylxanthines in rat cerebellar Purkinje cells

artículo científico publicado en 1993

Allele-dependent changes of olivocerebellar circuit properties in the absence of the voltage-gated potassium channels Kv3.1 and Kv3.3.

artículo científico publicado en 2004

Alpha-parvalbumin reduces depolarization-induced elevations of cytosolic free calcium in human neuroblastoma cells.

artículo científico publicado en 1996

An NMDA receptor/nitric oxide cascade in presynaptic parallel fiber-Purkinje neuron long-term potentiation

artículo científico publicado en 2007

Assessing spatiotemporal variability of brain spontaneous activity by multiscale entropy and functional connectivity

artículo científico publicado en 2019

Audio-visual experience strengthens multisensory assemblies in adult mouse visual cortex

scientific article published on 12 December 2019

Behavioral motor dysfunction in Kv3-type potassium channel-deficient mice

artículo científico publicado en 2006

Biophysical characterization of the fluorescent protein voltage probe VSFP2.3 based on the voltage-sensing domain of Ci-VSP

artículo científico publicado el 6 de agosto de 2010

Blocking acid-sensing ion channel 1 alleviates Huntington's disease pathology via an ubiquitin-proteasome system-dependent mechanism

artículo científico publicado en 2008

Calcium signaling in mitral cell dendrites of olfactory bulbs of neonatal rats and mice during olfactory nerve Stimulation and beta-adrenoceptor activation.

artículo científico publicado en 2004

Calculation of calcium dynamics from single wavelength fura-2 fluorescence recordings

artículo científico publicado en 1991

Cardiac optogenetics: using light to monitor cardiac physiology

artículo científico publicado en 2017

Cellular localisation of metabotropic glutamate receptors in the mammalian optic nerve: a mechanism for axon-glia communication

artículo científico publicado en 1996

Cellular, and subcellular localization of the mGluR5a metabotropic glutamate receptor in rat spinal cord

artículo científico publicado en 1994

Characterization of a calcium-dependent current generating a slow afterdepolarization of CA3 pyramidal cells in rat hippocampal slice cultures

artículo científico publicado en 1993

Charge movement of a voltage-sensitive fluorescent protein

artículo científico publicado en 2009

Climbing Fibre Responses in Olivo-cerebellar Slice Cultures. I. Microelectrode Recordings from Purkinje Cells

artículo científico publicado en 1990

Climbing Fibre Responses in Olivo-cerebellar Slice Cultures. II. Dynamics of Cytosolic Calcium in Purkinje Cells

article

Climbing fiber-triggered metabotropic slow potentials enhance dendritic calcium transients and simple spike firing in cerebellar Purkinje cells

artículo científico publicado en 2007

Clustering of the group III metabotropic glutamate receptor 4a at parallel fiber synaptic terminals in the rat cerebellar molecular layer

artículo científico publicado en 1999

Combining Cortical Voltage Imaging and Hippocampal Electrophysiology for Investigating Global, Multi-Timescale Activity Interactions in the Brain

scientific article published in 2022

Comparative performance of a genetically-encoded voltage indicator and a blue voltage sensitive dye for large scale cortical voltage imaging

artículo científico publicado en 2015

Continuous presence of nerve growth factor is required for maintenance of cholinergic septal neurons in organotypic slice cultures

article

Contribution of plasma membrane Ca ATPase to cerebellar synapse function

artículo científico publicado en 2010

Corrigendum: Single-Neuron Level One-Photon Voltage Imaging With Sparsely Targeted Genetically Encoded Voltage Indicators

artículo científico publicado en 2019

Cortex-restricted disruption of NMDAR1 impairs neuronal patterns in the barrel cortex

scientific journal article

Cortical Entropy, Mutual Information and Scale-Free Dynamics in Waking Mice

artículo científico publicado en 2016

Cortical signatures of wakeful somatosensory processing

artículo científico publicado en 2018

Cytosolic calcium during glucose deprivation in hippocampal pyramidal cells of rats

artículo científico publicado en 1990

Delayed increase of extracellular arginine, the nitric oxide precursor, following electrical white matter stimulation in rat cerebellar slices

artículo científico publicado en 1992

Delivery of differentiation factors by mesoporous silica particles assists advanced differentiation of transplanted murine embryonic stem cells.

artículo científico publicado en 2013

Design and characterization of a DNA-encoded, voltage-sensitive fluorescent protein.

artículo científico publicado en 2001

Distinct spatiotemporal activity in principal neurons of the mouse olfactory bulb in anesthetized and awake states ⬇️

artículo científico publicado el 28 de marzo de 2013

Diversity of neuronal elements and circuitry in the cerebellar nuclei.

artículo científico

Dynamics of maculo-ocular reflexes in the frog

article

Early sodium elevations induced by combined oxygen and glucose deprivation in pyramidal cortical neurons

artículo científico publicado en 1998

Effect of voltage sensitive fluorescent proteins on neuronal excitability

artículo científico publicado en 2009

Electrotonic coupling of excitable and nonexcitable cells in the heart revealed by optogenetics

artículo científico publicado en 2016

Engineering and characterization of an enhanced fluorescent protein voltage sensor

artículo científico publicado en 2007

Engineering and characterization of an enhanced fluorescent protein voltage sensor

Engineering of a genetically encodable fluorescent voltage sensor exploiting fast Ci-VSP voltage-sensing movements

artículo científico publicado en 2008

Enhanced synaptic inhibition in the cerebellar cortex of the ataxic PMCA2(-/-) knockout mouse

artículo científico publicado en 2013

Evidence Against a Role for Protein Kinase C in the Inhibition of the Calcium-activated Potassium Current IAHPby Muscarinic Stimulants in Rat Hippocampal Neurons

article

Evidence for N-methyl-D-aspartic acid receptor-mediated modulation of the commissural input to central vestibular neurons of the frog

artículo científico publicado en 1987

Excitatory synaptic potentials in neurons of the deep nuclei in olivo-cerebellar slice cultures

artículo científico publicado en 1992

Expanding the toolbox for remote control of neuronal circuits

artículo científico publicado en 2008

Exploration of fluorescent protein voltage probes based on circularly permuted fluorescent proteins

artículo científico publicado en 2009

Exploration of genetically encoded voltage indicators based on a chimeric voltage sensing domain

artículo científico publicado en 2014

Expression and coupling to polyphosphoinositide hydrolysis of group I metabotropic glutamate receptors in early postnatal and adult rat brain

artículo científico publicado en 1997

Facilitated Anion Transport Induces Hyperpolarization of the Cell Membrane That Triggers Differentiation and Cell Death in Cancer Stem Cells

artículo científico publicado en 2015

Functional classification of neurons in the mouse lateral cerebellar nuclei

artículo científico publicado en 2011

Functional contributions of the plasma membrane calcium ATPase and the sodium–calcium exchanger at mouse parallel fibre to Purkinje neuron synapses ⬇️

artículo científico publicado el 9 de noviembre de 2012

Functional integration of calcium regulatory mechanisms at Purkinje neuron synapses

artículo científico publicado en 2012

Functional topology of the mossy fibre-granule cell--Purkinje cell system revealed by imaging of intrinsic fluorescence in mouse cerebellum

artículo científico publicado en 2004

GABAergic synaptic communication in the GABAergic and non-GABAergic cells in the deep cerebellar nuclei.

artículo científico publicado en 2008

Genetically Encoded Fluorescent Calcium and Voltage Indicators

artículo científico publicado en 2019

Genetically encoded fluorescent sensors of membrane potential

artículo científico publicado en 2008

Genetically encoded optical indicators for the analysis of neuronal circuits

artículo científico publicado en 2012

Genetically encoded probes for optical imaging of brain electrical activity

artículo científico

Genetically encoded voltage indicators for large scale cortical imaging come of age.

artículo científico publicado en 2015

Genetically engineered fluorescent voltage reporters

artículo científico

Glutamate uptake controls expression of a slow postsynaptic current mediated by mGluRs in cerebellar Purkinje cells

artículo científico publicado en 2002

Glutamate-induced elevations in intracellular chloride concentration in hippocampal cell cultures derived from EYFP-expressing mice

artículo científico publicado en 2004

GlyT2+ neurons in the lateral cerebellar nucleus.

artículo científico publicado en 2010

High speed functional imaging with source localized multifocal two-photon microscopy

artículo científico publicado en 2018

High-frequency network oscillations in cerebellar cortex.

artículo científico publicado en 2008

Hippocampal LTP triggers proteasome-mediated SPAR degradation in CA1 neurons.

artículo científico publicado en 2011

Imaging brain electric signals with genetically targeted voltage-sensitive fluorescent proteins

artículo científico publicado en 2010

Imaging neural circuit dynamics with a voltage-sensitive fluorescent protein.

artículo científico publicado en 2012

Imaging of Brain Slices with a Genetically Encoded Voltage Indicator.

artículo científico publicado en 2017

Imaging of gene expression during long-term potentiation.

artículo científico publicado en 2004

Imaging the awake visual cortex with a genetically encoded voltage indicator

artículo científico publicado en 2015

Immortalized hypothalamic neurons express metabotropic glutamate receptors positively coupled to cyclic AMP formation

artículo científico publicado en 1996

Immunocytochemical Visualization of the mG1uR1 a Metabotropic Glutamate Receptor at Synapses of Corticothalamic Terminals Originating from Area 17 of the Rat

article

Immunohistochemical distribution of metabotropic glutamate receptor subtypes mGluR1b, mGluR2/3, mGluR4a and mGluR5 in human hippocampus

artículo científico publicado en 1996

Immunohistochemical localization of the mGluR1beta metabotropic glutamate receptor in the adult rodent forebrain: evidence for a differential distribution of mGluR1 splice variants

artículo científico publicado en 1998

In vivo calcium imaging from genetically specified target cells in mouse cerebellum.

artículo científico publicado en 2006

Interaction of Cupidin/Homer2 with two actin cytoskeletal regulators, Cdc42 small GTPase and Drebrin, in dendritic spines

artículo científico publicado en 2009

Interaction of Kv3 potassium channels and resurgent sodium current influences the rate of spontaneous firing of Purkinje neurons.

artículo científico publicado en 2006

Involvement of protein synthesis and degradation in long-term potentiation of Schaffer collateral CA1 synapses.

artículo científico publicado en 2006

L-homocysteic acid but not L-glutamate is an endogenous N-methyl-D-aspartic acid receptor preferring agonist in rat neocortical neurons in vitro

artículo científico publicado en 1987

Light and electron microscopic demonstration of mGluR5 metabotropic glutamate receptor immunoreactive neuronal elements in the rat cerebellar cortex

artículo científico publicado en 1997

Long-term depression at olfactory nerve synapses.

artículo científico publicado en 2005

Mammalian cortical voltage imaging using genetically encoded voltage indicators: a review honoring professor Amiram Grinvald.

artículo científico

Metabotropic glutamate receptor agonists stimulate polyphosphoinositide hydrolysis in primary cultures of rat hepatocytes

article

Metabotropic glutamate receptors in the cerebellum with a focus on their function in Purkinje cells.

artículo científico publicado en 2002

Metabotropic glutamate receptors: a new target for the therapy of neurodegenerative disorders?

artículo científico publicado en 1996

Metabotropic glutamate receptors: electrical and chemical signaling properties.

artículo científico publicado en 2002

Model of very fast (> 75 Hz) network oscillations generated by electrical coupling between the proximal axons of cerebellar Purkinje cells.

artículo científico publicado en 2008

Modulation of excitation by metabotropic glutamate receptors.

artículo científico publicado en 2008

Molecular cloning, functional expression and pharmacological characterization of the human metabotropic glutamate receptor type 4

artículo científico publicado en 1995

Morphological and electrophysiological properties of GABAergic and non-GABAergic cells in the deep cerebellar nuclei.

artículo científico publicado en 2006

Multiphasic responses of cerebellar Purkinje cells to 1S,3R-ACPD: an in vivo study

article

Nanobiotechnology: Remote control of cells

artículo científico publicado en 2010

Olfactory nerve stimulation-evoked mGluR1 slow potentials, oscillations, and calcium signaling in mouse olfactory bulb mitral cells

artículo científico publicado en 2006

Olfactory nerve stimulation-induced calcium signaling in the mitral cell distal dendritic tuft

artículo científico publicado en 2005

Optical Recording of Electrical Activity of Cortical Layer 2/3 Pyramidal Neurons Using A Genetically-Encoded Voltage Probe

Optical imaging as a link between cellular neurophysiology and circuit modeling

artículo científico publicado en 2009

Optical imaging of postsynaptic odor representation in the glomerular layer of the mouse olfactory bulb

artículo científico publicado en 2009

Optical measurement of mGluR1 conformational changes reveals fast activation, slow deactivation, and sensitization.

scholarly article

Optical probing of neuronal circuit dynamics: genetically encoded versus classical fluorescent sensors.

artículo científico publicado en 2006

Optical recordings of membrane potential using genetically targeted voltage-sensitive fluorescent proteins ⬇️

artículo científico publicado el 1 de mayo de 2003

Optical voltage imaging in neurons: moving from technology development to practical tool

scientific article published on 08 November 2019

Optogenetic electrophysiology: a new approach to combine cellular and systems physiology

artículo científico publicado en 2012

Optogenetic monitoring of membrane potentials.

artículo científico publicado en 2010

Optogenetic reporters.

artículo científico publicado en 2012

Optogenetic sensors in the zebrafish heart: a novel in vivo electrophysiological tool to study cardiac arrhythmogenesis

scientific article published on 09 September 2018

Optogenetic targeting of cardiac myocytes and non-myocytes: Tools, challenges and utility.

artículo científico publicado en 2017

Optogenetics enlightens neuroscience drug discovery.

artículo científico publicado en 2015

Organotypic Co-Cultures of Rat Locus Coeruleus and Hippocampus

article

Pharmacological characterization of MCCG and MAP4 at the mGluR1b, mGluR2 and mGluR4a human metabotropic glutamate receptor subtypes

artículo científico publicado en 1995

Pharmacological characterization of synaptic transmission through mGluRs in rat cerebellar slices

artículo científico publicado en 1997

Phenylglycine derivatives antagonize the excitatory response of Purkinje cells to 1S,3R-ACPD: an in vivo and in vitro study

article

Plasma membrane Ca2+ ATPase 2 contributes to short-term synapse plasticity at the parallel fiber to Purkinje neuron synapse

scientific journal article

Potassium conductances in hippocampal neurons blocked by excitatory amino-acid transmitters

artículo científico publicado en 1990

Presynaptic plasma membrane Ca2+ ATPase isoform 2a regulates excitatory synaptic transmission in rat hippocampal CA3

artículo científico publicado en 2007

Presynaptically expressed long-term depression at cerebellar parallel fiber synapses

artículo científico publicado en 2008

Probing neuronal activities with genetically encoded optical indicators: from a historical to a forward-looking perspective.

artículo científico

Profiling of trans-azetidine-2,4-dicarboxylic acid at the human metabotropic glutamate receptors mGlu1b, -2, -4a and -5a

scientific article published on 01 February 1995

Quantification of the density of cooperative neighboring synapses required to evoke endocannabinoid signaling.

artículo científico publicado en 2013

Red-shifted voltage-sensitive fluorescent proteins.

artículo científico publicado en 2009

Reduced expression of the Ca(2+) transporter protein PMCA2 slows Ca(2+) dynamics in mouse cerebellar Purkinje neurones and alters the precision of motor coordination

artículo científico publicado en 2010

Responses to Metabotropic Glutamate Receptor Activation in Cerebellar Purkinje Cells: Induction of an Inward Current

artículo científico publicado en 1992

Route to genetically targeted optical electrophysiology: development and applications of voltage-sensitive fluorescent proteins.

artículo científico publicado en 2015

Screening and Cellular Characterization of Genetically Encoded Voltage Indicators Based on Near-Infrared Fluorescent Proteins

scientific article published on 16 October 2020

Second and third generation voltage-sensitive fluorescent proteins for monitoring membrane potential.

artículo científico publicado en 2009

Sensing Cardiac Electrical Activity With a Cardiac Myocyte--Targeted Optogenetic Voltage Indicator

artículo científico publicado en 2015

Signal transmission in the parallel fiber-Purkinje cell system visualized by high-resolution imaging.

artículo científico publicado en 1994

Single-Neuron Level One-Photon Voltage Imaging With Sparsely Targeted Genetically Encoded Voltage Indicators

scientific article published on 14 February 2019

Sodium imaging of climbing fiber innervation fields in developing mouse Purkinje cells

artículo científico publicado en 2003

Spectrally-resolved response properties of the three most advanced FRET based fluorescent protein voltage probes

artículo científico publicado en 2009

State-Dependent Modulation of Slow Wave Motifs towards Awakening

artículo científico publicado en 2017

Subcellular localization of the voltage-dependent potassium channel Kv3.1b in postnatal and adult rat medial nucleus of the trapezoid body.

artículo científico publicado en 2003

Subcellular resolution three-dimensional light-field imaging with genetically encoded voltage indicators

artículo científico publicado en 2020

The relationship between blood flow and neuronal activity in the rodent olfactory bulb

artículo científico publicado en 2007

The serotonin 2A receptor agonist 25CN-NBOH increases murine heart rate and neck-arterial blood flow in a temperature-dependent manner

artículo científico publicado en 2020

Tolerance and Tachyphylaxis to Head Twitches Induced by the 5-HT2A Agonist 25CN-NBOH in Mice.

artículo científico publicado en 2018

Tools for observing and controlling specific molecular or physiological pathways in intact cells and tissues. Preface

artículo científico publicado en 2012

Toward the second generation of optogenetic tools

artículo científico publicado en 2010

Transfer of Kv3.1 voltage sensor features to the isolated Ci-VSP voltage-sensing domain

artículo científico publicado en 2012

Transgenic Strategies for Sparse but Strong Expression of Genetically Encoded Voltage and Calcium Indicators.

artículo científico publicado en 2017

Transgenic mice expressing a fluorescent in vivo label in a distinct subpopulation of neocortical layer 5 pyramidal cells.

artículo científico publicado en 2004

Transgenic mice expressing a pH and Cl- sensing yellow-fluorescent protein under the control of a potassium channel promoter

artículo científico publicado en 2002

Two new non-competitive mGlu1 receptor antagonists are potent tools to unravel functions of this mGlu receptor subtype

artículo científico publicado en 2007

Two-Photon Imaging of Electrical Activity in Mouse Cortex using a Genetically-Encoded Voltage Indicator

Two-photon voltage imaging using a genetically encoded voltage indicator.

artículo científico publicado en 2013

Voltage imaging of waking mouse cortex reveals emergence of critical neuronal dynamics

artículo científico publicado en 2014

Voltage-imaging and simulation of effects of voltage- and agonist-activated conductances on soma-dendritic voltage coupling in cerebellar Purkinje cells

scientific article published on 01 December 1994

mGluR5 metabotropic glutamate receptor distribution in rat and human spinal cord: a developmental study.

artículo científico publicado en 1997

Dominio Público Uruguay está sostenido por:

Acerca de Dominio Público Uruguay

Ayuda