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Lista de obras de David J. Adams

(E)-3-Furan-2-yl-N-p-tolyl-acrylamide and its Derivative DM489 Decrease Neuropathic Pain in Mice Predominantly by α7 Nicotinic Acetylcholine Receptor Potentiation

scientific article published on 19 October 2020

888 α-Conotoxin Vc1.1 Targets GABAB Receptors Modulating CaV2.2 and CaV2.3 Calcium Channels in Sensory Pathways Mediating Chronic Visceral Pain

A Distinct Functional Site in Ω-Neurotoxins: Novel Antagonists of Nicotinic Acetylcholine Receptors from Snake Venom.

artículo científico publicado en 2015

A Novel Lid-Covering Peptide Inhibitor of Nicotinic Acetylcholine Receptors Derived from αD-Conotoxin GeXXA.

artículo científico publicado en 2017

A new level of conotoxin diversity, a non-native disulfide bond connectivity in alpha-conotoxin AuIB reduces structural definition but increases biological activity

artículo científico publicado en 2002

A novel mechanism of inhibition of high-voltage activated calcium channels by α-conotoxins contributes to relief of nerve injury-induced neuropathic pain

artículo científico publicado en 2011

A novel α-conopeptide Eu1.6 inhibits N-type (CaV2.2) calcium channels and exhibits potent analgesic activity

artículo científico publicado en 2018

Adenosine triphosphate acts as both a competitive antagonist and a positive allosteric modulator at recombinant N-methyl-D-aspartate receptors

artículo científico publicado en 2004

Alanine scan of α-conotoxin RegIIA reveals a selective α3β4 nicotinic acetylcholine receptor antagonist.

artículo científico publicado en 2014

Allosteric alpha 1-adrenoreceptor antagonism by the conopeptide rho-TIA.

artículo científico publicado en 2003

Alpha-conotoxin AuIB isomers exhibit distinct inhibitory mechanisms and differential sensitivity to stoichiometry of alpha3beta4 nicotinic acetylcholine receptors.

artículo científico publicado en 2010

Alpha-conotoxins PnIA and [A10L]PnIA stabilize different states of the alpha7-L247T nicotinic acetylcholine receptor.

artículo científico publicado en 2003

Alpha-selenoconotoxins, a new class of potent alpha7 neuronal nicotinic receptor antagonists

artículo científico publicado en 2006

Analgesic alpha-conotoxins Vc1.1 and Rg1A inhibit N-type calcium channels in rat sensory neurons via GABAB receptor activation.

artículo científico publicado en 2008

Analgesic conopeptides targeting G protein-coupled receptors reduce excitability of sensory neurons

artículo científico publicado en 2017

Analgesic conotoxins: block and G protein-coupled receptor modulation of N-type (Ca(V) 2.2) calcium channels

artículo científico publicado en 2012

Analgesic transient receptor potential vanilloid-1-active compounds inhibit native and recombinant T-type calcium channels

artículo científico publicado en 2019

Are 9 10 Nicotinic Acetylcholine Receptors a Pain Target for -Conotoxins?

artículo científico publicado en 2007

Are nicotinic acetylcholine receptors coupled to G proteins?

artículo científico publicado en 2013

Auxiliary subunit regulation of high-voltage activated calcium channels expressed in mammalian cells

artículo científico publicado en 2004

Backbone cyclization of analgesic conotoxin GeXIVA facilitates direct folding of the ribbon isomer

artículo científico publicado en 2017

Basal nonselective cation permeability in rat cardiac microvascular endothelial cells

artículo científico publicado en 2002

Biomedical applications of trastuzumab: as a therapeutic agent and a targeting ligand.

artículo científico

Block of Voltage-Gated Calcium Channels by Peptide Toxins

Bombesin receptors as potential targets for anticancer drug delivery and imaging

scientific article published on 08 July 2019

Bombesin-conjugated nanoparticles improve the cytotoxic efficacy of docetaxel against gastrin-releasing but androgen-independent prostate cancer

artículo científico publicado en 2015

Bradykinin and inositol 1,4,5-trisphosphate-stimulated calcium release from intracellular stores in cultured bovine endothelial cells

artículo científico publicado en 1989

CHAPTER 4. Venoms-Based Drug Discovery: Bioassays, Electrophysiology, High-Throughput Screens and Target Identification

Caffeine‐evoked, calcium‐sensitive membrane currents in rabbit aortic endothelial cells ⬇️

artículo científico publicado el 1 de mayo de 1995

Calcium channels controlling acetylcholine release from preganglionic nerve terminals in rat autonomic ganglia

artículo científico publicado en 2000

Calcium entry through receptor-operated channels in bovine pulmonary artery endothelial cells

artículo científico publicado en 1987

Calcium permeability and modulation of nicotinic acetylcholine receptor-channels in rat parasympathetic neurons

artículo científico publicado en 1992

Calcium-activated potassium channels in native endothelial cells from rabbit aorta: conductance, Ca2+ sensitivity and block ⬇️

artículo científico publicado el 1 de septiembre de 1992

Characteristics of sodium and calcium conductance changes produced by membrane depolarization in an Aplysia neurone ⬇️

artículo científico publicado el 1 de abril de 1979

Chemical and functional identification and characterization of novel sulfated alpha-conotoxins from the cone snail Conus anemone.

artículo científico publicado en 2004

Chemical engineering and structural and pharmacological characterization of the α-scorpion toxin OD1

artículo científico publicado en 2013

Chemical modification of conotoxins to improve stability and activity

artículo científico publicado en 2007

Chemical synthesis and folding of APETx2, a potent and selective inhibitor of acid sensing ion channel 3.

artículo científico publicado en 2009

Ciguatoxin (CTX-1) modulates single tetrodotoxin-sensitive sodium channels in rat parasympathetic neurones

artículo científico publicado en 1998

Ciguatoxin-induced oscillations in membrane potential and action potential firing in rat parasympathetic neurons

artículo científico publicado en 2002

Conotoxin αD-GeXXA utilizes a novel strategy to antagonize nicotinic acetylcholine receptors

artículo científico publicado en 2015

Conotoxins targeting neuronal voltage-gated sodium channel subtypes: potential analgesics?

artículo científico publicado en 2012

Contribution of membrane receptor signalling to chronic visceral pain

artículo científico publicado en 2018

Cyclic RGDfK Peptide Functionalized Polymeric Nanocarriers for Targeting Gemcitabine to Ovarian Cancer Cells

artículo científico publicado en 2016

Cyclic analogues of α-conotoxin Vc1.1 inhibit colonic nociceptors and provide analgesia in a mouse model of chronic abdominal pain

artículo científico publicado en 2017

Cyclic-RGDfK peptide conjugated succinoyl-TPGS nanomicelles for targeted delivery of docetaxel to integrin receptor over-expressing angiogenic tumours

artículo científico publicado en 2015

Determination of the α-Conotoxin Vc1.1 Binding Site on the α9α10 Nicotinic Acetylcholine Receptor

scientific article published on 29 April 2013

Developmental changes in expression of GABAA receptor-channels in rat intrinsic cardiac ganglion neurones

artículo científico publicado en 2005

Dicarba analogues of α-conotoxin RgIA. Structure, stability, and activity at potential pain targets

artículo científico publicado en 2014

Dicarba α-conotoxin Vc1.1 analogues with differential selectivity for nicotinic acetylcholine and GABAB receptors

artículo científico publicado en 2013

Differential Cav2.1 and Cav2.3 channel inhibition by baclofen and α-conotoxin Vc1.1 via GABAB receptor activation

artículo científico publicado en 2014

Dimerization of α-Conotoxins as a Strategy to Enhance the Inhibition of the Human α7 and α9α10 Nicotinic Acetylcholine Receptors

artículo científico publicado en 2020

Distinct activities of novel neurotoxins from Australian venomous snakes for nicotinic acetylcholine receptors

artículo científico publicado en 2007

Divalent ion currents and the delayed potassium conductance in an Aplysia neurone ⬇️

artículo científico publicado el 1 de julio de 1980

Drysdalin, an antagonist of nicotinic acetylcholine receptors highlights the importance of functional rather than structural conservation of amino acid residues

artículo científico publicado en 2019

Effects of arginine 10 to lysine substitution on ω-conotoxin CVIE and CVIF block of Cav2.2 channels.

artículo científico publicado en 2014

Effects of cyclization on stability, structure, and activity of α-conotoxin RgIA at the α9α10 nicotinic acetylcholine receptor and GABA(B) receptor

artículo científico publicado en 2011

Effects of linker sequence modifications on the structure, stability, and biological activity of a cyclic α-conotoxin

scientific article published on 01 November 2016

Embryonic toxin expression in the cone snail Conus victoriae: primed to kill or divergent function?

artículo científico publicado en 2011

Engineering stable peptide toxins by means of backbone cyclization: stabilization of the alpha-conotoxin MII.

artículo científico publicado en 2005

Ethanol reduces excitatory postsynaptic current duration at a crustacean neuromuscular junction

artículo científico publicado en 1977

Formulation and dosage of therapeutic nanosuspension for active targeting of docetaxel (WO 2014210485A1).

artículo científico publicado en 2016

Fulditoxin, representing a new class of dimeric snake toxins, defines novel pharmacology at nicotinic ACh receptors

artículo científico publicado en 2020

Functional Modulation of the Human Voltage-Gated Sodium Channel Na<sub>V</sub>1.8 by Auxiliary β Subunits

scientific article published on 14 December 2020

Functional maturation of isolated neural progenitor cells from the adult rat hippocampus

artículo científico publicado en 2004

Funnel web spider venom produces spontaneous action potentials in nerve

artículo científico publicado en 1977

Hydrophobic residues at position 10 of α-conotoxin PnIA influence subtype selectivity between α7 and α3β2 neuronal nicotinic acetylcholine receptors

artículo científico publicado en 2014

Identification of a Novel Class of Nicotinic Receptor Antagonists

artículo científico publicado en 2006

Identification of a Novel O-Conotoxin Reveals an Unusual and Potent Inhibitor of the Human α9α10 Nicotinic Acetylcholine Receptor

artículo científico publicado en 2017

Identifying key amino acid residues that affect α-conotoxin AuIB inhibition of α3β4 nicotinic acetylcholine receptors.

artículo científico publicado en 2013

Improving Efficacy, Oral Bioavailability, and Delivery of Paclitaxel Using Protein-Grafted Solid Lipid Nanoparticles.

artículo científico publicado en 2016

Inhibition of Human CaV2.3 Channels via μ-, δ- and κ-Opioid Receptor Activation

Inhibition of cholinergic pathways in Drosophila melanogaster by α-conotoxins

artículo científico publicado en 2014

Inhibition of human N- and T-type calcium channels by an ortho-phenoxyanilide derivative, MONIRO-1.

artículo científico publicado en 2017

Inhibition of neuronal nicotinic acetylcholine receptor subtypes by alpha-Conotoxin GID and analogues

artículo científico publicado en 2008

Inhibition of the norepinephrine transporter by the venom peptide chi-MrIA. Site of action, Na+ dependence, and structure-activity relationship

artículo científico publicado en 2003

Inhibitors of calcium buffering depress evoked transmitter release at the squid giant synapse

artículo científico publicado en 1985

Interaction of Synthetic Human SLURP-1 with the Nicotinic Acetylcholine Receptors.

artículo científico publicado en 2017

Interaction of internal anions with potassium channels of the squid giant axon ⬇️

artículo científico publicado el 1 de octubre de 1983

Interactions of the α3β2 Nicotinic Acetylcholine Receptor Interfaces with α-Conotoxin LsIA and its Carboxylated C-terminus Analogue: Molecular Dynamics Simulations

artículo científico publicado en 2020

Intrathecal α-conotoxins Vc1.1, AuIB and MII acting on distinct nicotinic receptor subtypes reverse signs of neuropathic pain

scientific article published on 27 January 2012

Intravenous anaesthetics inhibit nicotinic acetylcholine receptor-mediated currents and Ca2+ transients in rat intracardiac ganglion neurons

artículo científico publicado en 2005

In vivo and in vitro testing of native α-conotoxins from the injected venom of Conus purpurascens.

artículo científico publicado en 2017

Ionic channels in vascular endothelial cells

artículo científico publicado en 1994

Ionic currents in molluscan soma

artículo científico publicado en 1980

Ionic currents in response to membrane depolarization in an Aplysia neurone ⬇️

artículo científico publicado el 1 de abril de 1979

Is the A-ring lactone of brevetoxin PbTx-3 required for sodium channel orphan receptor binding and activity?

artículo científico publicado en 1994

Isolation and characterization of α-conotoxin LsIA with potent activity at nicotinic acetylcholine receptors

artículo científico publicado en 2013

Isolation and structure-activity of mu-conotoxin TIIIA, a potent inhibitor of tetrodotoxin-sensitive voltage-gated sodium channels

artículo científico publicado en 2006

Isolation, characterization and total regioselective synthesis of the novel μO-conotoxin MfVIA from Conus magnificus that targets voltage-gated sodium channels

artículo científico publicado en 2012

Isolation, structure, and activity of GID, a novel alpha 4/7-conotoxin with an extended N-terminal sequence

artículo científico publicado en 2003

Isolation, synthesis and characterization of ω-TRTX-Cc1a, a novel tarantula venom peptide that selectively targets L-type Cav channels

artículo científico publicado en 2014

K(ir) and K(v) channels regulate electrical properties and proliferation of adult neural precursor cells

artículo científico publicado en 2007

Ketamine inhibits synaptic transmission and nicotinic acetylcholine receptor-mediated responses in rat intracardiac ganglia in situ

scientific article published on 03 January 2020

Key Structural Determinants in the Agonist Binding Loops of Human β2 and β4 Nicotinic Acetylcholine Receptor Subunits Contribute to α3β4 Subtype Selectivity of α-Conotoxins

artículo científico publicado en 2016

Kv3.1 channels stimulate adult neural precursor cell proliferation and neuronal differentiation

artículo científico publicado en 2013

Large-conductance calcium-activated potassium channels in neonatal rat intracardiac ganglion neurons

artículo científico publicado en 2001

Less is More: Design of a Highly Stable Disulfide-Deleted Mutant of Analgesic Cyclic α-Conotoxin Vc1.1.

artículo científico publicado en 2015

Liposome reconstitution and modulation of recombinant N-methyl-D-aspartate receptor channels by membrane stretch

artículo científico publicado en 2007

Localization of Nav 1.7 in the normal and injured rodent olfactory system indicates a critical role in olfaction, pheromone sensing and immune function

artículo científico publicado en 2012

M4 Muscarinic Receptor Activation Modulates Calcium Channel Currents in Rat Intracardiac Neurons ⬇️

artículo científico publicado el 1 de octubre de 1997

Mechanism of direct Cav2.2 channel block by the κ-opioid receptor agonist U50488H.

artículo científico publicado en 2016

Mechanisms of conotoxin inhibition of N-type (Ca(v)2.2) calcium channels

artículo científico publicado en 2013

Met-enkephalin-induced mobilization of intracellular Ca2+ in rat intracardiac ganglion neurones

artículo científico publicado en 1999

Modulation of human Nav1.7 channel gating by synthetic α-scorpion toxin OD1 and its analogs

artículo científico publicado en 2015

Molecular Basis for Differential Sensitivity of α-Conotoxin RegIIA at Rat and Human Neuronal Nicotinic Acetylcholine Receptors.

artículo científico publicado en 2015

Molecular Determinants Conferring the Stoichiometric-Dependent Activity of α-Conotoxins at the Human α9α10 Nicotinic Acetylcholine Receptor Subtype

artículo científico publicado en 2018

Molecular and Functional Characterization of Neurogenin-2 Induced Human Sensory Neurons

artículo científico publicado en 2020

Molecular dynamics simulations of dihydro-β-erythroidine bound to the human α4β2 nicotinic acetylcholine receptor

scientific article published on 07 June 2019

Molecular engineering of conotoxins: the importance of loop size to alpha-conotoxin structure and function

artículo científico publicado en 2008

Monoclonal Antibody-Conjugated Dendritic Nanostructures for siRNA Delivery

artículo científico publicado en 2019

Monovalent and divalent cation permeability and block of neuronal nicotinic receptor channels in rat parasympathetic ganglia

artículo científico publicado en 1995

Muscarinic and nicotinic ACh receptor activation differentially mobilize Ca2+ in rat intracardiac ganglion neurons

artículo científico publicado en 2003

NEDD4-2 as a potential candidate susceptibility gene for epileptic photosensitivity

artículo científico publicado en 2007

NMDA receptor subunit-dependent modulation by conantokin-G and Ala7-conantokin-G.

artículo científico publicado en 2005

NMR Structure of μ-Conotoxin GIIIC: Leucine 18 Induces Local Repacking of the N-Terminus Resulting in Reduced Na Channel Potency

scientific article published on 22 October 2018

Neural control of the heart: developmental changes in ionic conductances in mammalian intrinsic cardiac neurons

artículo científico publicado en 2002

Neuronal voltage-gated sodium channel subtypes: key roles in inflammatory and neuropathic pain.

artículo científico publicado en 2006

Neuronally micro-conotoxins from Conus striatus utilize an alpha-helical motif to target mammalian sodium channels

artículo científico publicado en 2008

Novel analgesic ω-conotoxins from the vermivorous cone snail Conus moncuri provide new insights into the evolution of conopeptides

scientific article published in Scientific Reports

Novel mechanism of voltage-gated N-type (Cav2.2) calcium channel inhibition revealed through α-conotoxin Vc1.1 activation of the GABA(B) receptor

artículo científico publicado en 2014

Omega-conotoxin CVIB differentially inhibits native and recombinant N- and P/Q-type calcium channels

artículo científico publicado en 2007

Omega-conotoxin CVID inhibits a pharmacologically distinct voltage-sensitive calcium channel associated with transmitter release from preganglionic nerve terminals

artículo científico publicado en 2003

Overexpressed Ca(v)beta3 inhibits N-type (Cav2.2) calcium channel currents through a hyperpolarizing shift of ultra-slow and closed-state inactivation

artículo científico publicado en 2004

Peptide grafted and self-assembled poly(γ-glutamic acid)-phenylalanine nanoparticles targeting camptothecin to glioma.

artículo científico publicado en 2017

Physiological roles of ion channels in adult neural stem cells and their progeny

artículo científico publicado en 2010

Potassium channels and membrane potential in the modulation of intracellular calcium in vascular endothelial cells

artículo científico publicado en 2004

Pre- and postsynaptic actions of ATP on neurotransmission in rat submandibular ganglia

artículo científico publicado en 2001

Purification of immature neuronal cells from neural stem cell progeny

artículo científico publicado en 2011

Purinergic receptor activation inhibits mitogen-stimulated proliferation in primary neurospheres from the adult mouse subventricular zone

artículo científico publicado en 2007

Reactive oxygen species modulate neuronal excitability in rat intrinsic cardiac ganglia

artículo científico publicado en 2009

RegIIA: an α4/7-conotoxin from the venom of Conus regius that potently blocks α3β4 nAChRs.

artículo científico publicado en 2011

Regulation of neuronal voltage-gated sodium channels by the ubiquitin-protein ligases Nedd4 and Nedd4-2.

artículo científico publicado en 2004

Regulation of the voltage-gated K(+) channels KCNQ2/3 and KCNQ3/5 by serum- and glucocorticoid-regulated kinase-1.

artículo científico publicado en 2008

Regulation of the voltage-gated K(+) channels KCNQ2/3 and KCNQ3/5 by ubiquitination. Novel role for Nedd4-2

scientific journal article

Regulation of voltage-gated ion channels in excitable cells by the ubiquitin ligases Nedd4 and Nedd4-2.

scientific article published on January 2011

Resting membrane potential and potassium currents in cultured parasympathetic neurones from rat intracardiac ganglia ⬇️

artículo científico publicado el 1 de octubre de 1992

Role of CysI–CysIII Disulfide Bond on the Structure and Activity of α-Conotoxins at Human Neuronal Nicotinic Acetylcholine Receptors.

artículo científico publicado en 2017

Scanning mutagenesis of alpha-conotoxin Vc1.1 reveals residues crucial for activity at the alpha9alpha10 nicotinic acetylcholine receptor

artículo científico publicado en 2009

Selective modulation of neuronal nicotinic acetylcholine receptor channel subunits by Go-protein subunits.

artículo científico publicado en 2005

Single Amino Acid Substitutions in α-Conotoxin PnIA Shift Selectivity for Subtypes of the Mammalian Neuronal Nicotinic Acetylcholine Receptor

artículo científico publicado en 1999

Sodium and calcium gating currents in an Aplysia neurone ⬇️

artículo científico publicado el 1 de junio de 1979

Solution structure of mu-conotoxin PIIIA, a preferential inhibitor of persistent tetrodotoxin-sensitive sodium channels

artículo científico publicado en 2002

Solving the alpha-conotoxin folding problem: efficient selenium-directed on-resin generation of more potent and stable nicotinic acetylcholine receptor antagonists.

artículo científico publicado en 2010

Stabilization of α-Conotoxin AuIB: Influences of Disulfide Connectivity and Backbone Cyclization

scientific article published on 20 August 2010

Stoichiometry dependent inhibition of rat α3β4 nicotinic acetylcholine receptor by the ribbon isomer of α-conotoxin AuIB

scientific article published on 21 July 2018

Store-Operated Ca(2+) Entry (SOCE) and Purinergic Receptor-Mediated Ca(2+) Homeostasis in Murine bv2 Microglia Cells: Early Cellular Responses to ATP-Mediated Microglia Activation

artículo científico publicado en 2016

Structural basis of the potency and selectivity of Urotoxin, a potent Kv1 blocker from scorpion venom

artículo científico publicado en 2019

Structure and activity of alpha-conotoxin PeIA at nicotinic acetylcholine receptor subtypes and GABA(B) receptor-coupled N-type calcium channels

artículo científico publicado en 2011

Structure of α-conotoxin BuIA: influences of disulfide connectivity on structural dynamics ⬇️

artículo científico publicado en 2007

Structure-Activity Studies of Cysteine-Rich α-Conotoxins that Inhibit High-Voltage-Activated Calcium Channels via GABA(B) Receptor Activation Reveal a Minimal Functional Motif.

artículo científico publicado en 2016

Structures of muO-conotoxins from Conus marmoreus. I nhibitors of tetrodotoxin (TTX)-sensitive and TTX-resistant sodium channels in mammalian sensory neurons.

artículo científico publicado en 2004

Structure–Activity Studies Reveal the Molecular Basis for GABAB-Receptor Mediated Inhibition of High Voltage-Activated Calcium Channels by α-Conotoxin Vc1.1

artículo científico publicado en 2018

Synthesis, structure elucidation, in vitro biological activity, toxicity, and Caco-2 cell permeability of lipophilic analogues of alpha-conotoxin MII.

artículo científico publicado en 2003

Targeting of N-Type Calcium Channels via GABAB-Receptor Activation by α-Conotoxin Vc1.1 Variants Displaying Improved Analgesic Activity

scholarly article by Fengtao Cai et al published 25 October 2018 in Journal of Medicinal Chemistry

Tertiapin-Q blocks recombinant and native large conductance K+ channels in a use-dependent manner

artículo científico publicado en 2005

The Engineering of an Orally Active Conotoxin for the Treatment of Neuropathic Pain

artículo científico publicado en 2010

The alpha2delta auxiliary subunit reduces affinity of omega-conotoxins for recombinant N-type (Cav2.2) calcium channels

artículo científico publicado en 2004

The doublecortin-expressing population in the developing and adult brain contains multipotential precursors in addition to neuronal-lineage cells.

artículo científico publicado en 2007

The relationship of brevetoxin 'length' and A-ring functionality to binding and activity in neuronal sodium channels

artículo científico publicado en 1995

The synthesis, structural characterization, and receptor specificity of the alpha-conotoxin Vc1.1.

artículo científico publicado en 2006

The tarantula toxin β/δ-TRTX-Pre1a highlights the importance of the S1-S2 voltage-sensor region for sodium channel subtype selectivity.

artículo científico publicado en 2017

The three-dimensional structure of the analgesic alpha-conotoxin, RgIA.

artículo científico publicado en 2008

Total Synthesis of the Analgesic Conotoxin MrVIB through Selenocysteine-Assisted Folding

article

Transforming conotoxins into cyclotides: Backbone cyclization of P-superfamily conotoxins

artículo científico publicado en 2015

Trastuzumab-grafted PAMAM dendrimers for the selective delivery of anticancer drugs to HER2-positive breast cancer

artículo científico publicado en 2016

VIP and PACAP potentiation of nicotinic ACh-evoked currents in rat parasympathetic neurons is mediated by G-protein activation

scientific article published on 01 July 2000

Voltage sensitivity of inhibitory postsynaptic current in Aplysia buccal ganglia

artículo científico publicado en 1976

Voltage-Gated Calcium Channels in Nociception

Voltage-Gated R-Type Calcium Channel Inhibition via Human μ-, δ-, and κ-opioid Receptors Is Voltage-Independently Mediated by Gβγ Protein Subunits

artículo científico publicado en 2015

Voltage-dependent inhibition of recombinant NMDA receptor-mediated currents by 5-hydroxytryptamine

artículo científico publicado en 2005

Voltage-dependent sodium and calcium currents in cultured parasympathetic neurones from rat intracardiac ganglia ⬇️

artículo científico publicado el 1 de octubre de 1992

alpha-conotoxin EpI, a novel sulfated peptide from Conus episcopatus that selectively targets neuronal nicotinic acetylcholine receptors

artículo científico publicado en 1998

muO-conotoxin MrVIB selectively blocks Nav1.8 sensory neuron specific sodium channels and chronic pain behavior without motor deficits

artículo científico publicado en 2006

omega-Conotoxin inhibition of excitatory synaptic transmission evoked by dorsal root stimulation in rat superficial dorsal horn

artículo científico publicado en 2008

α-Conotoxin Vc1.1 Structure-Activity Relationship at the Human α9α10 Nicotinic Acetylcholine Receptor Investigated by Minimal Side Chain Replacement

artículo científico publicado en 2019

α-Conotoxin Vc1.1 inhibits human dorsal root ganglion neuroexcitability and mouse colonic nociception via GABAB receptors.

artículo científico publicado en 2016

α-Conotoxin dendrimers have enhanced potency and selectivity for homomeric nicotinic acetylcholine receptors.

artículo científico publicado en 2015

α-Conotoxins active at α3-containing nicotinic acetylcholine receptors and their molecular determinants for selective inhibition.

artículo científico publicado en 2017

γ-Aminobutyric acid type B (GABAB) receptor expression is needed for inhibition of N-type (Cav2.2) calcium channels by analgesic α-conotoxins

artículo científico publicado en 2012

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