Lista de obras - Simak Ali - Dominio Público Uruguay

A novel hotspot specific isothermal amplification method for detection of the common PIK3CA p.H1047R breast cancer mutation

scientific article published on 12 March 2020

A novel pyrazolo[1,5-a]pyrimidine is a potent inhibitor of cyclin-dependent protein kinases 1, 2, and 9, which demonstrates antitumor effects in human tumor xenografts following oral administration

artículo científico publicado en 2010

A simple laboratory practical to illustrate RNA mediated gene interference using drosophila cell culture

artículo científico publicado en 2010

ABC-transporter upregulation mediates resistance to the CDK7 inhibitors THZ1 and ICEC0942

artículo científico publicado en 2019

An important role for BRCA1 in breast cancer progression is indicated by its loss in a large proportion of non-familial breast cancers

artículo científico publicado en 1998

Antiestrogens and their therapeutic applications in breast cancer and other diseases

artículo científico publicado en 2011

Author Correction: The responses of cancer cells to PLK1 inhibitors reveal a novel protective role for p53 in maintaining centrosome separation.

artículo científico publicado en 2018

Complete nucleotide sequence of the genomic ovine beta-lactoglobulin gene

artículo científico publicado en 1988

Critical research gaps and translational priorities for the successful prevention and treatment of breast cancer

artículo científico publicado en 2013

Development of a cyclin-dependent kinase inhibitor devoid of ABC transporter-dependent drug resistance

artículo científico publicado en 2013

Development of a novel molecular sensor for imaging estrogen receptor-coactivator protein-protein interactions

artículo científico publicado en 2012

Developmental regulation of the sheep β-lactoglobulin gene in the mammary gland of transgenic mice ⬇️

artículo científico publicado el 1 de enero de 1991

Differential epigenetic reprogramming in response to specific endocrine therapies promotes cholesterol biosynthesis and cellular invasion

artículo científico publicado en 2015

Differential oestrogen receptor binding is associated with clinical outcome in breast cancer

artículo científico publicado en 2012

Discovery of naturally occurring ESR1 mutations in breast cancer cell lines modelling endocrine resistance

artículo científico publicado en 2017

ESR1 mutant breast cancers show elevated basal cytokeratins and immune activation

artículo científico publicado en 2022

Elevated ERK1/ERK2/estrogen receptor cross-talk enhances estrogen-mediated signaling during long-term estrogen deprivation

artículo científico publicado en 2005

Endonuclease FEN1 coregulates ERα activity and provides a novel drug interface in tamoxifen resistant breast cancer

scientific article published on 19 March 2020

Enhanced estrogen receptor (ER) alpha, ERBB2, and MAPK signal transduction pathways operate during the adaptation of MCF-7 cells to long term estrogen deprivation

artículo científico publicado en 2003

Estrogen receptor alpha in human breast cancer: occurrence and significance

artículo científico publicado en 2000

Gene expression in the mammary gland

artículo científico publicado en 1990

Genome-wide alterations of uracil distribution patterns in human DNA upon chemotherapeutic treatments

scientific article published on 21 September 2020

Genomic modelling of the ESR1 Y537S mutation for evaluating function and new therapeutic approaches for metastatic breast cancer.

artículo científico publicado en 2016

Histone deacetylase inhibitor trichostatin A represses estrogen receptor alpha-dependent transcription and promotes proteasomal degradation of cyclin D1 in human breast carcinoma cell lines

artículo científico publicado en 2004

Human Estrogen Receptor β Binds DNA in a Manner Similar to and Dimerizes with Estrogen Receptor α ⬇️

artículo científico publicado el 10 de octubre de 1997

ICI182,780 induces p21Waf1 gene transcription through releasing histone deacetylase 1 and estrogen receptor alpha from Sp1 sites to induce cell cycle arrest in MCF-7 breast cancer cell line

artículo científico publicado en 2004

Immunodetection of multiple species of retinoic acid receptor alpha: evidence for phosphorylation

artículo científico publicado en 1992

Induction of APOBEC3-mediated genomic damage in urothelium implicates BK polyomavirus (BKPyV) as a hit-and-run driver for bladder cancer

artículo científico publicado en 2022

Light-triggered enzymatic reactions in nested vesicle reactors.

artículo científico publicado en 2018

Localization and expression of the human estrogen receptor beta gene in uterine leiomyomata

artículo científico publicado en 1998

Mechanisms of tamoxifen resistance: increased estrogen receptor-HER2/neu cross-talk in ER/HER2-positive breast cancer

artículo científico publicado en 2004

Molecular changes associated with the acquisition of oestrogen hypersensitivity in MCF-7 breast cancer cells on long-term oestrogen deprivation

artículo científico publicado en 2002

Phosphorylation of estrogen receptor-alpha at Ser167 is indicative of longer disease-free and overall survival in breast cancer patients

artículo científico publicado en 2007

Reporter gene assay demonstrates functional differences in estrogen receptor activity in purified breast cancer cells: A pilot study ⬇️

artículo científico publicado el 10 de diciembre de 2003

Retinoic acid receptor-beta: immunodetection and phosphorylation on tyrosine residues

artículo científico publicado en 1992

Ribociclib Induces Broad Chemotherapy Resistance and EGFR Dependency in ESR1 Wildtype and Mutant Breast Cancer

artículo científico publicado en 2021

Shallow WGS of individual CTCs identifies actionable targets for informing treatment decisions in metastatic breast cancer

artículo científico publicado en 2022

Silencing of androgen-regulated genes using a fusion of AR with the PLZF transcriptional repressor

artículo científico publicado en 2004

The DEAD box RNA helicases p68 (Ddx5) and p72 (Ddx17): novel transcriptional co-regulators.

artículo científico publicado en 2008

The cooked food derived carcinogen 2-amino-1-methyl-6-phenylimidazo[4,5-b] pyridine is a potent oestrogen: a mechanistic basis for its tissue-specific carcinogenicity

artículo científico publicado en 2004

The liver receptor homolog-1 regulates estrogen receptor expression in breast cancer cells

artículo científico publicado en 2010

The molecular manipulation of milk composition

artículo científico publicado en 1989

The responses of cancer cells to PLK1 inhibitors reveal a novel protective role for p53 in maintaining centrosome separation

artículo científico publicado en 2017

The transcriptional repressor REV-ERB as a novel target for disease

artículo científico publicado en 2020

Transient over-expression of estrogen receptor-α in breast cancer cells promotes cell survival and estrogen-independent growth

artículo científico publicado en 2010

p53 controls expression of the DNA deaminase APOBEC3B to limit its potential mutagenic activity in cancer cells

artículo científico publicado en 2017

Lista de obras de Simak Ali

A novel hotspot specific isothermal amplification method for detection of the common PIK3CA p.H1047R breast cancer mutation

A novel pyrazolo[1,5-a]pyrimidine is a potent inhibitor of cyclin-dependent protein kinases 1, 2, and 9, which demonstrates antitumor effects in human tumor xenografts following oral administration

A simple laboratory practical to illustrate RNA mediated gene interference using drosophila cell culture

ABC-transporter upregulation mediates resistance to the CDK7 inhibitors THZ1 and ICEC0942

An important role for BRCA1 in breast cancer progression is indicated by its loss in a large proportion of non-familial breast cancers

Antiestrogens and their therapeutic applications in breast cancer and other diseases

Author Correction: The responses of cancer cells to PLK1 inhibitors reveal a novel protective role for p53 in maintaining centrosome separation.

Complete nucleotide sequence of the genomic ovine beta-lactoglobulin gene

Critical research gaps and translational priorities for the successful prevention and treatment of breast cancer

Development of a cyclin-dependent kinase inhibitor devoid of ABC transporter-dependent drug resistance

Development of a novel molecular sensor for imaging estrogen receptor-coactivator protein-protein interactions

Developmental regulation of the sheep β-lactoglobulin gene in the mammary gland of transgenic mice ⬇️

Differential epigenetic reprogramming in response to specific endocrine therapies promotes cholesterol biosynthesis and cellular invasion

Differential oestrogen receptor binding is associated with clinical outcome in breast cancer

Discovery of naturally occurring ESR1 mutations in breast cancer cell lines modelling endocrine resistance

ESR1 mutant breast cancers show elevated basal cytokeratins and immune activation

Elevated ERK1/ERK2/estrogen receptor cross-talk enhances estrogen-mediated signaling during long-term estrogen deprivation

Endonuclease FEN1 coregulates ERα activity and provides a novel drug interface in tamoxifen resistant breast cancer

Enhanced estrogen receptor (ER) alpha, ERBB2, and MAPK signal transduction pathways operate during the adaptation of MCF-7 cells to long term estrogen deprivation

Estrogen receptor alpha in human breast cancer: occurrence and significance

Gene expression in the mammary gland

Genome-wide alterations of uracil distribution patterns in human DNA upon chemotherapeutic treatments

Genomic modelling of the ESR1 Y537S mutation for evaluating function and new therapeutic approaches for metastatic breast cancer.

Histone deacetylase inhibitor trichostatin A represses estrogen receptor alpha-dependent transcription and promotes proteasomal degradation of cyclin D1 in human breast carcinoma cell lines

Human Estrogen Receptor β Binds DNA in a Manner Similar to and Dimerizes with Estrogen Receptor α ⬇️

ICI182,780 induces p21Waf1 gene transcription through releasing histone deacetylase 1 and estrogen receptor alpha from Sp1 sites to induce cell cycle arrest in MCF-7 breast cancer cell line

Immunodetection of multiple species of retinoic acid receptor alpha: evidence for phosphorylation

Induction of APOBEC3-mediated genomic damage in urothelium implicates BK polyomavirus (BKPyV) as a hit-and-run driver for bladder cancer

Light-triggered enzymatic reactions in nested vesicle reactors.

Localization and expression of the human estrogen receptor beta gene in uterine leiomyomata

Mechanisms of tamoxifen resistance: increased estrogen receptor-HER2/neu cross-talk in ER/HER2-positive breast cancer

Molecular changes associated with the acquisition of oestrogen hypersensitivity in MCF-7 breast cancer cells on long-term oestrogen deprivation

Phosphorylation of estrogen receptor-alpha at Ser167 is indicative of longer disease-free and overall survival in breast cancer patients

Reporter gene assay demonstrates functional differences in estrogen receptor activity in purified breast cancer cells: A pilot study ⬇️

Retinoic acid receptor-beta: immunodetection and phosphorylation on tyrosine residues

Ribociclib Induces Broad Chemotherapy Resistance and EGFR Dependency in ESR1 Wildtype and Mutant Breast Cancer

Shallow WGS of individual CTCs identifies actionable targets for informing treatment decisions in metastatic breast cancer

Silencing of androgen-regulated genes using a fusion of AR with the PLZF transcriptional repressor

The DEAD box RNA helicases p68 (Ddx5) and p72 (Ddx17): novel transcriptional co-regulators.

The cooked food derived carcinogen 2-amino-1-methyl-6-phenylimidazo[4,5-b] pyridine is a potent oestrogen: a mechanistic basis for its tissue-specific carcinogenicity

The liver receptor homolog-1 regulates estrogen receptor expression in breast cancer cells

The molecular manipulation of milk composition

The responses of cancer cells to PLK1 inhibitors reveal a novel protective role for p53 in maintaining centrosome separation

The transcriptional repressor REV-ERB as a novel target for disease

Transient over-expression of estrogen receptor-α in breast cancer cells promotes cell survival and estrogen-independent growth

p53 controls expression of the DNA deaminase APOBEC3B to limit its potential mutagenic activity in cancer cells