Lista de obras - Susana de la Luna - Dominio Público Uruguay

A comprehensive proteomics-based interaction screen that links DYRK1A to RNF169 and to the DNA damage response

scientific article published on 12 April 2019

A new aspartyl protease on 21q22.3, BACE2, is highly similar to Alzheimer's amyloid precursor protein beta-secretase

artículo científico publicado en 2000

A new member of the DP family, DP-3, with distinct protein products suggests a regulatory role for alternative splicing in the cell cycle transcription factor DRTF1/E2F.

artículo científico publicado en 1995

Alu-splice cloning of human Intersectin (ITSN), a putative multivalent binding protein expressed in proliferating and differentiating neurons and overexpressed in Down syndrome

artículo científico publicado en 1999

Characterization of a mouse model overexpressing beta-site APP-cleaving enzyme 2 reveals a new role for BACE2.

artículo científico publicado en 2009

Chromatin-wide profiling of DYRK1A reveals a role as a gene-specific RNA polymerase II CTD kinase.

artículo científico publicado en 2015

Cold shock induces the insertion of a cryptic exon in the neurofibromatosis type 1 (NF1) mRNA

artículo científico publicado en 2000

Complex structure of the nuclear translocation signal of influenza virus polymerase PA subunit

artículo científico publicado en 1994

Construction of cell lines that regulate by temperature the amplification and expression of influenza virus non-structural protein genes

artículo científico publicado en 1986

Cooperation to amplify gene-dosage-imbalance effects

artículo científico publicado en 2006

DYRK family of protein kinases: evolutionary relationships, biochemical properties, and functional roles

artículo científico publicado en 2010

DYRK1A Kinase Positively Regulates Angiogenic Responses in Endothelial Cells.

artículo científico publicado en 2018

DYRK1A accumulates in splicing speckles through a novel targeting signal and induces speckle disassembly

artículo científico publicado en 2003

DYRK1A autophosphorylation on serine residue 520 modulates its kinase activity via 14-3-3 binding

artículo científico publicado en 2007

DYRK1A modulates c-MET in pancreatic ductal adenocarcinoma to drive tumour growth

artículo científico publicado en 2018

DYRK1A overexpression in pancreatic ductal adenocarcinoma contributes to tumor growth

scholarly article by Jeroni Luna et al published June 2015 in Pancreatology

DYRK1A-mediated phosphorylation of GluN2A at Ser(1048) regulates the surface expression and channel activity of GluN1/GluN2A receptors

artículo científico publicado en 2014

Differential expression of members of the RCAN family of calcineurin regulators suggests selective functions for these proteins in the brain

artículo científico publicado en 2007

Distinct mechanisms of nuclear accumulation regulate the functional consequence of E2F transcription factors ⬇️

artículo científico publicado el 1 de noviembre de 1997

Dyrk1A expression pattern supports specific roles of this kinase in the adult central nervous system

artículo científico publicado en 2003

Efficient transformation of mammalian cells with constructs containing a puromycin-resistance marker

article

Epitope mapping of cross-reactive monoclonal antibodies specific for the influenza A virus PA and PB2 polypeptides

artículo científico publicado en 1995

Eukaryotic translation initiation factor 4GI is a cellular target for NS1 protein, a translational activator of influenza virus

artículo científico publicado en 2000

Genome-wide analysis of histidine repeats reveals their role in the localization of human proteins to the nuclear speckles compartment

artículo científico publicado en 2009

Identification of PatL1, a human homolog to yeast P body component Pat1

artículo científico publicado en 2007

Impaired development of neocortical circuits contributes to the neurological alterations in DYRK1A haploinsufficiency syndrome

scientific article published on 01 March 2019

Individual expression of influenza virus PA protein induces degradation of coexpressed proteins.

artículo científico publicado en 1995

Influenza virus NS1 protein interacts with viral transcription-replication complexes in vivo

artículo científico publicado en 1997

Influenza virus naked RNA can be expressed upon transfection into cells co-expressing the three subunits of the polymerase and the nucleoprotein from simian virus 40 recombinant viruses.

artículo científico publicado en 1993

Integration of a growth-suppressing BTB/POZ domain protein with the DP component of the E2F transcription factor

artículo científico publicado en 1999

Intersectin 1 forms a complex with adaptor protein Ruk/CIN85 in vivo independently of epidermal growth factor stimulation

artículo científico publicado en 2009

Intersectin 2, a new multimodular protein involved in clathrin-mediated endocytosis

artículo científico publicado en 2000

Key Role of Amino Acid Repeat Expansions in the Functional Diversification of Duplicated Transcription Factors

artículo científico publicado en 2015

Molecular cloning and sequencing of influenza virus A/Victoria/3/75 polymerase genes: sequence evolution and prediction of possible functional domains

artículo científico publicado en 1989

Monoclonal antibodies against influenza virus PB2 and NP polypeptides interfere with the initiation step of viral mRNA synthesis in vitro

artículo científico publicado en 1994

Mutational analysis of the influenza virus A/Victoria/3/75 PA protein: studies of interaction with PB1 protein and identification of a dominant negative mutant

artículo científico publicado en 1996

Nuclear accumulation of the E2F heterodimer regulated by subunit composition and alternative splicing of a nuclear localization signal

article

Nuclear transport of influenza virus polymerase PA protein.

artículo científico publicado en 1992

Overexpression of tau protein in COS-1 cells results in the stabilization of centrosome-independent microtubules and extension of cytoplasmic processes

artículo científico publicado en 1994

Permanent cell lines established from ts-COS cells that regulate by temperature the amplification and expression of cloned genes

artículo científico publicado en 1987

Permanent cell lines that show temperature-dependent expression of adenovirus virus-associated RNA.

artículo científico publicado en 1989

Phosphorylation of calcipressin 1 increases its ability to inhibit calcineurin and decreases calcipressin half-life

artículo científico publicado en 2003

Regulated segregation of kinase Dyrk1A during asymmetric neural stem cell division is critical for EGFR-mediated biased signaling.

artículo científico publicado en 2010

Regulation of gene amplification and expression in cells that constitutively express a temperature sensitive SV40 T-antigen.

artículo científico publicado en 1985

Renaming the DSCR1/Adapt78 gene family as RCAN: regulators of calcineurin.

artículo científico publicado en 2007

Resistance to foot-and-mouth disease virus mediated by trans-acting cellular products

artículo científico publicado en 1989

Splice variants of the dual specificity tyrosine phosphorylation-regulated kinase 4 (DYRK4) differ in their subcellular localization and catalytic activity

artículo científico publicado en 2010

Sprouty2-mediated inhibition of fibroblast growth factor signaling is modulated by the protein kinase DYRK1A.

artículo científico publicado en 2008

Structural determinants of KvLQT1 control by the KCNE family of proteins

artículo científico publicado en 2001

Synthesis of biologically active influenza virus core proteins using a vaccinia virus-T7 RNA polymerase expression system

artículo científico publicado en 1994

TFIIIC Binding to Alu Elements Controls Gene Expression via Chromatin Looping and Histone Acetylation

artículo científico publicado en 2019

TFIIIC dynamically binds Alu elements to control gene expression through chromatin looping

article

The DYRK Family of Kinases in Cancer: Molecular Functions and Therapeutic Opportunities

artículo científico publicado en 2020

The RCAN carboxyl end mediates calcineurin docking-dependent inhibition via a site that dictates binding to substrates and regulators.

scholarly article

The molecular basis of glutamate formiminotransferase deficiency

scientific journal article

The protein kinase DYRK1A regulates caspase-9-mediated apoptosis during retina development

artículo científico publicado en 2008

pac Gene as Efficient Dominant Marker and Reporter Gene in Mammalian Cells

article

pac gene as efficient dominant marker and reporter gene in mammalian cells

artículo científico publicado en 1992

Lista de obras de Susana de la Luna

A comprehensive proteomics-based interaction screen that links DYRK1A to RNF169 and to the DNA damage response

A new aspartyl protease on 21q22.3, BACE2, is highly similar to Alzheimer's amyloid precursor protein beta-secretase

A new member of the DP family, DP-3, with distinct protein products suggests a regulatory role for alternative splicing in the cell cycle transcription factor DRTF1/E2F.

Alu-splice cloning of human Intersectin (ITSN), a putative multivalent binding protein expressed in proliferating and differentiating neurons and overexpressed in Down syndrome

Characterization of a mouse model overexpressing beta-site APP-cleaving enzyme 2 reveals a new role for BACE2.

Chromatin-wide profiling of DYRK1A reveals a role as a gene-specific RNA polymerase II CTD kinase.

Cold shock induces the insertion of a cryptic exon in the neurofibromatosis type 1 (NF1) mRNA

Complex structure of the nuclear translocation signal of influenza virus polymerase PA subunit

Construction of cell lines that regulate by temperature the amplification and expression of influenza virus non-structural protein genes

Cooperation to amplify gene-dosage-imbalance effects

DYRK family of protein kinases: evolutionary relationships, biochemical properties, and functional roles

DYRK1A Kinase Positively Regulates Angiogenic Responses in Endothelial Cells.

DYRK1A accumulates in splicing speckles through a novel targeting signal and induces speckle disassembly

DYRK1A autophosphorylation on serine residue 520 modulates its kinase activity via 14-3-3 binding

DYRK1A modulates c-MET in pancreatic ductal adenocarcinoma to drive tumour growth

DYRK1A overexpression in pancreatic ductal adenocarcinoma contributes to tumor growth

DYRK1A-mediated phosphorylation of GluN2A at Ser(1048) regulates the surface expression and channel activity of GluN1/GluN2A receptors

Differential expression of members of the RCAN family of calcineurin regulators suggests selective functions for these proteins in the brain

Distinct mechanisms of nuclear accumulation regulate the functional consequence of E2F transcription factors ⬇️

Dyrk1A expression pattern supports specific roles of this kinase in the adult central nervous system

Efficient transformation of mammalian cells with constructs containing a puromycin-resistance marker

Epitope mapping of cross-reactive monoclonal antibodies specific for the influenza A virus PA and PB2 polypeptides

Eukaryotic translation initiation factor 4GI is a cellular target for NS1 protein, a translational activator of influenza virus

Genome-wide analysis of histidine repeats reveals their role in the localization of human proteins to the nuclear speckles compartment

Identification of PatL1, a human homolog to yeast P body component Pat1

Impaired development of neocortical circuits contributes to the neurological alterations in DYRK1A haploinsufficiency syndrome

Individual expression of influenza virus PA protein induces degradation of coexpressed proteins.

Influenza virus NS1 protein interacts with viral transcription-replication complexes in vivo

Influenza virus naked RNA can be expressed upon transfection into cells co-expressing the three subunits of the polymerase and the nucleoprotein from simian virus 40 recombinant viruses.

Integration of a growth-suppressing BTB/POZ domain protein with the DP component of the E2F transcription factor

Intersectin 1 forms a complex with adaptor protein Ruk/CIN85 in vivo independently of epidermal growth factor stimulation

Intersectin 2, a new multimodular protein involved in clathrin-mediated endocytosis

Key Role of Amino Acid Repeat Expansions in the Functional Diversification of Duplicated Transcription Factors

Molecular cloning and sequencing of influenza virus A/Victoria/3/75 polymerase genes: sequence evolution and prediction of possible functional domains

Monoclonal antibodies against influenza virus PB2 and NP polypeptides interfere with the initiation step of viral mRNA synthesis in vitro

Mutational analysis of the influenza virus A/Victoria/3/75 PA protein: studies of interaction with PB1 protein and identification of a dominant negative mutant

Nuclear accumulation of the E2F heterodimer regulated by subunit composition and alternative splicing of a nuclear localization signal

Nuclear transport of influenza virus polymerase PA protein.

Overexpression of tau protein in COS-1 cells results in the stabilization of centrosome-independent microtubules and extension of cytoplasmic processes

Permanent cell lines established from ts-COS cells that regulate by temperature the amplification and expression of cloned genes

Permanent cell lines that show temperature-dependent expression of adenovirus virus-associated RNA.

Phosphorylation of calcipressin 1 increases its ability to inhibit calcineurin and decreases calcipressin half-life

Regulated segregation of kinase Dyrk1A during asymmetric neural stem cell division is critical for EGFR-mediated biased signaling.

Regulation of gene amplification and expression in cells that constitutively express a temperature sensitive SV40 T-antigen.

Renaming the DSCR1/Adapt78 gene family as RCAN: regulators of calcineurin.

Resistance to foot-and-mouth disease virus mediated by trans-acting cellular products

Splice variants of the dual specificity tyrosine phosphorylation-regulated kinase 4 (DYRK4) differ in their subcellular localization and catalytic activity

Sprouty2-mediated inhibition of fibroblast growth factor signaling is modulated by the protein kinase DYRK1A.

Structural determinants of KvLQT1 control by the KCNE family of proteins

Synthesis of biologically active influenza virus core proteins using a vaccinia virus-T7 RNA polymerase expression system

TFIIIC Binding to Alu Elements Controls Gene Expression via Chromatin Looping and Histone Acetylation

TFIIIC dynamically binds Alu elements to control gene expression through chromatin looping

The DYRK Family of Kinases in Cancer: Molecular Functions and Therapeutic Opportunities

The RCAN carboxyl end mediates calcineurin docking-dependent inhibition via a site that dictates binding to substrates and regulators.

The molecular basis of glutamate formiminotransferase deficiency

The protein kinase DYRK1A regulates caspase-9-mediated apoptosis during retina development

pac Gene as Efficient Dominant Marker and Reporter Gene in Mammalian Cells

pac gene as efficient dominant marker and reporter gene in mammalian cells