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Lista de obras de Sunil Laxman

A minimal "push-pull" bistability model explains oscillations between quiescent and proliferative cell states

scientific article published on 25 July 2018

A tRNA modification balances carbon and nitrogen metabolism by regulating phosphate homeostasis

scientific article published on 01 July 2019

A versatile LC-MS/MS approach for comprehensive, quantitative analysis of central metabolic pathways

artículo científico publicado en 2018

Anabolic SIRT4 Exerts Retrograde Control over TORC1 Signaling by Glutamine Sparing in the Mitochondria

scientific article published on 03 January 2020

Behavior of a metabolic cycling population at the single cell level as visualized by fluorescent gene expression reporters

artículo científico publicado en 2010

Characterization of a novel cAMP-binding, cAMP-specific cyclic nucleotide phosphodiesterase (TcrPDEB1) from Trypanosoma cruzi

artículo científico publicado en 2006

Conceptualizing Eukaryotic Metabolic Sensing and Signaling

artículo científico publicado en 2017

Concerted effort: oscillations in global gene expression during nematode development

artículo científico publicado en 2014

Correction: Metabolic constraints drive self-organization of specialized cell groups

artículo científico publicado en 2020

Correction: Resource plasticity-driven carbon-nitrogen budgeting enables specialization and division of labor in a clonal community

artículo científico publicado en 2021

Cyclic nucleotide signaling mechanisms in trypanosomes: possible targets for therapeutic agents.

artículo científico publicado en 2007

Cyclic nucleotide specific phosphodiesterases of the kinetoplastida: a unified nomenclature.

artículo científico publicado en 2005

Decoding the stem cell quiescence cycle--lessons from yeast for regenerative biology

artículo científico publicado en 2015

Genome-scale reconstruction of Gcn4/ATF4 networks driving a growth program

scientific article published on 30 December 2020

Hydrolysis products of cAMP analogs cause transformation of Trypanosoma brucei from slender to stumpy-like forms.

artículo científico publicado en 2006

Metabolic constraints drive self-organization of specialized cell groups

artículo científico publicado en 2019

Metabolite Regulation of Nuclear Localization of Carbohydrate-response Element-binding Protein (ChREBP): ROLE OF AMP AS AN ALLOSTERIC INHIBITOR

artículo científico publicado en 2016

Methionine at the Heart of Anabolism and Signaling: Perspectives From Budding Yeast

artículo científico publicado en 2019

Methionine coordinates a hierarchically organized anabolic program enabling proliferation

article

Methionine inhibits autophagy and promotes growth by inducing the SAM-responsive methylation of PP2A

artículo científico publicado en 2013

Methionine is a signal of amino acid sufficiency that inhibits autophagy through the methylation of PP2A.

artículo científico publicado en 2013

Methylated PP2A stabilizes Gcn4 to enable a methionine-induced anabolic program

scientific article published on 29 October 2020

Multiple TORC1-associated proteins regulate nitrogen starvation-dependent cellular differentiation in Saccharomyces cerevisiae.

artículo científico publicado en 2011

Npr2 inhibits TORC1 to prevent inappropriate utilization of glutamine for biosynthesis of nitrogen-containing metabolites

artículo científico publicado en 2014

Regulation of Hematopoiesis and Methionine Homeostasis by mTORC1 Inhibitor NPRL2

artículo científico publicado en 2015

Resource plasticity-driven carbon-nitrogen budgeting enables specialization and division of labor in a clonal community

artículo científico publicado en 2020

Steady-state and Flux-based Trehalose Estimation as an Indicator of Carbon Flow from Gluconeogenesis or Glycolysis

artículo científico publicado en 2020

Sulfur amino acids regulate translational capacity and metabolic homeostasis through modulation of tRNA thiolation

artículo científico publicado en 2013

Systems approaches for the study of metabolic cycles in yeast

artículo científico publicado en 2010

The E3 ubiquitin ligase Pib1 regulates effective gluconeogenic shutdown upon glucose availability

scientific article published on 11 October 2019

The Rad53CHK1/CHK2-Spt21NPAT and Tel1ATM axes couple glucose tolerance to histone dosage and subtelomeric silencing

artículo científico publicado en 2020

The glyoxylate shunt is essential for desiccation tolerance in C. elegans and budding yeast

artículo científico publicado en 2016

Thiol trapping and metabolic redistribution of sulfur metabolites enable cells to overcome cysteine overload

artículo científico publicado en 2017

Trypanosome cyclic nucleotide phosphodiesterase 2B binds cAMP through its GAF-A domain

artículo científico publicado en 2004

cAMP Signaling and Regulation by Phosphodiesterases in Trypanosomes

doctoral thesis by Sunil Laxman, 2006

tRNA wobble-uridine modifications as amino acid sensors and regulators of cellular metabolic state

scientific article published on 22 November 2019